[Hub]/) : Traits : Trunk fat-free mass :

chr14:20,843,889-24,016,366

Best TWAS P=1.14e-11 · Best GWAS P=5.48e-14 conditioned to 2.77e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ARHGEF40 0.34 0.32 enet 17 0.31 1.5e-17 -6.9 -6.8 1.1e-11 0.94 0.00 1.00 TRUE
2 GTEx Testis TOX4 0.31 0.00 enet 24 0.04 6.8e-03 -6.1 -6.3 3.4e-10 -0.07 0.08 0.05 TRUE
3 YFS Blood MRPL52 0.44 0.22 enet 27 0.28 2.2e-93 -4.1 5.7 1.3e-08 -0.03 1.00 0.00 TRUE
4 The Cancer Genome Atlas Breast Invasive Carcinoma METTL3 0.03 0.04 lasso 1 0.04 3.1e-08 -5.8 -5.8 4.9e-09 -0.06 0.08 0.92 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma METTL3 0.04 0.04 lasso 2 0.04 2.5e-05 -5.9 -5.9 3.5e-09 -0.05 0.05 0.91 FALSE
6 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma HOMEZ 0.19 0.01 blup 41 0.05 6.0e-03 2.9 5.3 1.2e-07 0.01 0.01 0.36 FALSE
7 The Cancer Genome Atlas Testicular Germ Cell Tumors METTL3 0.17 0.03 lasso 2 0.04 1.5e-02 -5.9 -5.8 7.0e-09 -0.05 0.02 0.39 FALSE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors RAB2B 0.12 0.04 blup 52 0.07 2.1e-03 -3.3 -5.3 1.5e-07 -0.08 0.01 0.36 TRUE
9 The Cancer Genome Atlas Thyroid Carcinoma HOMEZ 0.08 0.04 blup 42 0.04 7.6e-05 2.9 5.5 3.6e-08 0.01 0.07 0.21 TRUE