[Hub]/) : Traits : Trunk fat-free mass : ← →

chr14:24,039,559-25,605,046

Best TWAS P=4.46e-15 · Best GWAS P=1.11e-14 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	METSIM	Adipose	ADCY4	0.07	0.03	lasso	5	0.03	2.2e-05	7.4	7.8	4.5e-15	0.71	0.04	0.95	TRUE
17	GTEx	Spleen	NFATC4	0.45	0.00	enet	24	0.00	2.5e-01	5.1	-6.4	1.5e-10	-0.22	0.07	0.05	TRUE
25	The Cancer Genome Atlas	Colon Adenocarcinoma	ADCY4	0.07	0.02	lasso	4	0.03	4.7e-03	5.0	5.9	3.4e-09	0.70	0.03	0.76	TRUE
11	GTEx	Heart Left Ventricle	CBLN3	0.35	0.23	lasso	8	0.21	1.5e-11	5.2	-5.5	3.4e-08	-0.16	1.00	0.00	TRUE
15	GTEx	Nerve Tibial	KHNYN	0.34	0.10	lasso	8	0.15	1.6e-10	4.9	5.5	4.2e-08	0.10	1.00	0.00	TRUE
7	GTEx	Breast Mammary Tissue	LTB4R	0.30	0.18	lasso	4	0.16	2.3e-08	5.4	-5.4	7.5e-08	-0.63	0.77	0.22	TRUE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY4	0.06	0.06	lasso	6	0.09	3.0e-10	6.5	7.6	3.7e-14	0.75	0.06	0.94	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	ADCY4	0.07	0.09	lasso	3	0.08	4.4e-10	5.4	6.7	2.7e-11	0.73	0.88	0.12	FALSE
9	GTEx	Heart Atrial Appendage	ADCY4	0.28	0.14	lasso	4	0.10	2.1e-05	7.2	6.2	4.6e-10	0.48	0.08	0.81	FALSE
34	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R2	0.04	0.04	lasso	1	0.02	2.5e-02	6.2	-6.2	7.7e-10	-0.70	0.04	0.52	FALSE
23	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ADCY4	0.03	0.01	blup	75	0.03	1.1e-03	4.9	6.1	1.3e-09	0.71	0.06	0.70	FALSE
33	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R	0.04	0.01	blup	73	0.01	4.2e-02	6.2	-5.9	3.3e-09	-0.63	0.01	0.46	FALSE
13	GTEx	Lung	LTB4R	0.19	0.15	lasso	6	0.12	2.0e-09	5.2	-5.7	1.1e-08	-0.66	0.99	0.01	FALSE
14	GTEx	Muscle Skeletal	CBLN3	0.14	0.13	enet	7	0.13	4.8e-13	5.2	-5.7	1.1e-08	-0.13	1.00	0.00	FALSE
18	GTEx	Thyroid	ADCY4	0.13	0.13	lasso	6	0.09	1.0e-07	4.2	5.7	1.2e-08	0.51	0.37	0.63	FALSE
30	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LTB4R	0.16	0.05	blup	73	0.08	4.9e-04	3.7	-5.7	1.4e-08	-0.70	0.03	0.56	FALSE
22	YFS	Blood	KHNYN	0.36	0.20	enet	50	0.29	1.2e-96	4.7	5.6	1.8e-08	0.14	1.00	0.00	FALSE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	CBLN3	0.24	0.14	enet	8	0.13	4.0e-08	5.2	-5.6	2.7e-08	-0.14	0.33	0.67	FALSE
2	GTEx	Adipose Subcutaneous	ADCY4	0.08	0.04	lasso	3	0.03	3.3e-03	5.2	5.5	3.5e-08	0.62	0.20	0.26	FALSE
1	GTEx	Adipose Subcutaneous	KHNYN	0.30	0.14	lasso	2	0.14	7.1e-12	5.2	5.5	4.6e-08	0.09	1.00	0.00	FALSE
12	GTEx	Lung	KHNYN	0.14	0.08	lasso	5	0.05	9.7e-05	4.9	5.3	8.7e-08	0.08	0.66	0.01	FALSE
21	METSIM	Adipose	RABGGTA	0.10	0.06	lasso	9	0.08	5.5e-12	5.7	5.3	9.1e-08	0.62	0.99	0.01	FALSE
24	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CBLN3	0.34	0.15	lasso	5	0.14	2.4e-07	5.2	-5.3	9.6e-08	-0.17	0.32	0.65	FALSE
8	GTEx	Breast Mammary Tissue (Female)	CBLN3	0.42	0.20	lasso	4	0.28	5.9e-09	5.2	-5.3	1.0e-07	-0.08	0.84	0.02	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	LTB4R	0.08	0.05	lasso	8	0.05	1.7e-05	4.9	-5.3	1.3e-07	-0.58	0.63	0.16	FALSE
4	GTEx	Adipose Subcutaneous	LTB4R	0.14	0.12	lasso	3	0.12	1.3e-09	5.2	-5.2	1.5e-07	-0.61	0.93	0.07	FALSE
16	GTEx	Ovary	CBLN3	0.62	0.38	lasso	19	0.39	1.2e-10	5.1	-5.2	2.0e-07	-0.10	0.96	0.00	FALSE
3	GTEx	Adipose Subcutaneous	CBLN3	0.65	0.39	lasso	23	0.37	6.1e-32	5.1	-5.2	2.2e-07	-0.10	1.00	0.00	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	CBLN3	0.30	0.26	lasso	1	0.24	1.4e-17	5.2	-5.2	2.2e-07	-0.11	0.32	0.68	FALSE
6	GTEx	Artery Tibial	KHNYN	0.38	0.12	lasso	5	0.18	8.8e-14	4.9	5.2	2.3e-07	0.09	1.00	0.00	FALSE
5	GTEx	Artery Aorta	KHNYN	0.19	0.20	lasso	4	0.20	1.8e-11	4.7	5.2	2.4e-07	0.07	1.00	0.00	FALSE
10	GTEx	Heart Atrial Appendage	CBLN3	0.58	0.40	lasso	5	0.38	2.3e-18	5.2	-5.2	2.4e-07	-0.11	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CBLN3	0.37	0.35	lasso	4	0.34	4.4e-15	5.2	-5.2	2.6e-07	-0.09	0.32	0.68	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	CBLN3	0.38	0.30	lasso	9	0.30	2.7e-32	5.1	-5.2	2.6e-07	-0.12	0.33	0.67	FALSE
19	GTEx	Thyroid	LTB4R	0.30	0.18	lasso	2	0.17	1.0e-12	5.2	-5.1	2.8e-07	-0.60	1.00	0.00	FALSE