[Hub]/) : Traits : Trunk fat-free mass :

chr14:34,480,400-36,571,554

Best TWAS P=8.4e-13 · Best GWAS P=5.2e-10 conditioned to 0.127

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP2R3C 0.21 0.12 lasso 10 0.14 2.6e-11 -6.2 5.6 2.7e-08 -0.95 0.00 1.00 FALSE
2 GTEx Adipose Subcutaneous FAM177A1 0.19 0.06 lasso 8 0.11 3.6e-09 2.6 5.3 1.1e-07 -0.67 0.04 0.96 FALSE
3 GTEx Artery Tibial RP11-85K15.2 0.06 0.01 lasso 6 0.02 2.1e-02 -5.8 -5.8 7.1e-09 0.67 0.04 0.76 FALSE
4 GTEx Cells Transformed fibroblasts PPP2R3C 0.31 0.10 lasso 10 0.18 4.0e-13 -6.2 5.8 6.0e-09 -0.87 0.00 1.00 FALSE
5 GTEx Cells Transformed fibroblasts CFL2 0.14 0.08 enet 39 0.11 9.9e-09 -3.2 -7.2 8.4e-13 0.30 0.59 0.04 TRUE
6 GTEx Skin Sun Exposed Lower leg FAM177A1 0.19 0.04 lasso 10 0.10 1.7e-08 -4.6 5.1 2.8e-07 -0.72 0.01 0.99 FALSE
7 NTR Blood NFKBIA 0.26 0.09 lasso 10 0.12 3.4e-36 -4.8 -6.6 3.9e-11 0.42 0.84 0.15 TRUE
8 NTR Blood PPP2R3C 0.06 0.04 lasso 5 0.04 4.2e-14 4.4 -5.3 1.1e-07 0.37 0.95 0.04 FALSE
9 YFS Blood KIAA0391 0.29 0.36 lasso 7 0.38 5.8e-132 -6.2 -6.0 2.1e-09 0.99 0.00 1.00 FALSE
10 YFS Blood NFKBIA 0.24 0.11 enet 33 0.17 3.5e-53 -4.6 -6.6 3.8e-11 0.51 0.87 0.12 FALSE
11 YFS Blood PPP2R3C 0.53 0.46 bslmm 383 0.60 2.4e-254 4.4 -6.1 8.9e-10 0.63 0.95 0.05 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA0391 0.07 0.04 blup 110 0.04 1.9e-05 -3.5 5.6 2.4e-08 -0.83 0.03 0.97 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma PPP2R3C 0.08 0.04 blup 51 0.07 7.8e-09 -5.0 6.1 1.3e-09 -0.82 0.01 0.99 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma KIAA0391 0.12 0.11 enet 14 0.14 2.0e-13 -4.1 5.7 1.4e-08 -0.77 0.70 0.30 FALSE