TWAS hub - LOC284751

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1370	0.0350	1.1e-07	0.040	0.072	0.076	0.078	0.074	1.2e-05	3.8e-09	1.5e-09	9.1e-10	2.3e-09
2	NTR	Blood	0.0755	0.0174	1.6e-13	0.044	0.053	0.059	0.051	0.051	4.9e-14	1.6e-16	2.8e-18	4.3e-16	4.0e-16

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Breastfed as a baby	10.9	13.5	13.7	-3.7	-3.6
Serious illness, injury or assault to yourself	8.4	10.2	12.7	2.8	3.6
Tinnitus: Yes, now most or all of the time	7.5	8.8	12.6	2.2	3.5
Ever highly irritable/argumentative for 2 days	6.6	7.9	8.3	2.7	2.9
Asthma	6.3	12.4	12.9	3.6	3.5
Relative age of first facial hair	5.8	11.8	19.5	4.4	2.0
Asthma (self-reported)	5.7	11.4	12.6	3.5	3.2
Respiratory disease	5.3	11.7	12.1	3.4	3.5
Allergy	4.4	10.1	11.0	-3.3	-3.1
Hearing difficulty/problems with background noise	3.8	6.0	7.8	-2.1	-2.8
Medication: Ventolin 100micrograms inhaler	3.6	4.6	7.3	1.4	2.7
Ever had stillbirth, spontaneous miscarriage or termination	3.5	3.8	5.2	2.3	1.5
Arm fat-free mass (right)	3.4	17.2	24.8	-5.0	-3.1
Falls in the last year	3.3	4.4	4.9	2.0	2.2
Arm predicted mass (right)	3.2	16.4	23.8	-4.9	-3.0
Hayfever/allergic rhinitis (self-reported)	3.1	4.1	7.3	2.7	1.0
Trunk fat-free mass	3.0	17.4	26.3	-5.1	-2.9
Peak expiratory flow (PEF)	3.0	6.9	10.5	-1.8	-3.2
Impedance of arm (right)	2.9	13.4	19.3	4.4	2.7
Trunk predicted mass	2.8	16.2	25.0	-5.0	-2.7
Alzheimer’s Disease (in mother)	2.7	3.2	4.8	1.3	2.2
Blood White Count	2.7	20.0	20.2	-4.5	-4.5
Bilateral oophorectomy (both ovaries removed)	2.7	3.2	3.3	-1.8	-1.7
Breast Cancer	2.6	6.3	9.0	-1.9	-3.0
Taking other prescription medications	2.6	4.1	5.2	-1.7	-2.3
Arm fat-free mass (left)	2.6	13.4	20.2	-4.5	-2.6
Arm predicted mass (left)	2.6	13.4	19.4	-4.4	-2.7
Hearing difficulty/problems: Yes	2.5	3.8	5.8	-1.4	-2.4
Whole body water mass	2.5	14.4	21.4	-4.6	-2.7
Myopia	2.5	3.6	6.4	2.5	0.9
Type 2 Diabetes (T2D) (2012)	2.4	2.7	4.0	2.0	1.2
Medication: Levothyroxine sodium	2.4	4.1	5.9	-2.4	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.0	5.7	-2.1	-2.4
Whole body fat-free mass	2.4	13.6	20.3	-4.5	-2.6
Hearing aid user	2.3	2.7	2.8	-1.6	-1.7
Age started oral contraceptive pill	2.3	2.9	3.6	-1.5	-1.9
Type 2 Diabetes (T2D) (2018)	2.2	4.1	7.3	1.0	2.7
Ever used hormone-replacement therapy (HRT)	2.2	2.8	3.0	-1.7	-1.6
Deep venous thrombosis (DVT) (self-reported)	2.2	2.8	4.9	0.9	2.2
Relative age voice broke	2.1	3.2	5.9	2.4	0.7
Sitting height	2.1	15.3	15.8	-4.0	-3.8
Qualifications: O levels/GCSEs or equivalent	2.1	3.4	5.6	1.1	2.4
Basal metabolic rate	2.1	11.8	17.3	-4.2	-2.5
Alzheimer’s Disease (including proxy)	2.0	2.9	4.5	1.1	2.1
Number of full brothers	2.0	2.6	3.6	1.2	1.9
Crohns Disease (2017)	1.9	4.2	8.1	0.5	2.8
Blood Eosinophil Count	1.9	14.9	23.2	-2.6	-4.8
Impedance of arm (left)	1.9	8.7	14.0	3.7	1.9
Number of children fathered	1.9	2.2	3.7	0.9	1.9
Major Depression (MDD)	1.8	2.2	2.3	1.5	1.5
Qualifications: A levels/AS levels or equivalent	1.8	4.0	4.4	1.9	2.1
Blood clot in the leg (DVT)	1.8	2.3	4.0	0.8	2.0
Gout (self-reported)	1.8	2.5	3.7	-1.1	-1.9
Mouth/teeth dental problems: Mouth ulcers	1.8	2.8	5.5	2.3	0.3
Osteoporosis (self-reported)	1.8	2.2	2.7	-1.3	-1.6
Systolic blood pressure, automated reading	1.7	5.1	5.3	-2.2	-2.3
Chronic bronchitis/emphysema (father)	1.7	2.0	3.9	2.0	0.4
Sensitivity / hurt feelings	1.6	2.7	4.1	-1.2	-2.0
Medication: Co-codamol	1.6	1.8	1.9	-1.3	-1.4
Leg fat-free mass (left)	1.6	8.5	11.9	-3.5	-2.2
Leg predicted mass (left)	1.6	8.2	11.7	-3.4	-2.2
Age at last live birth	1.6	2.3	3.1	1.3	1.8
Leg predicted mass (right)	1.6	8.4	11.0	-3.3	-2.4
Impedance of whole body	1.6	8.1	13.1	3.6	1.8
Hair/balding pattern: Pattern 3	1.5	2.2	3.9	-2.0	0.7
Lung cancer (father)	1.5	1.8	3.6	1.9	0.2
Diabetes diagnosed by doctor	1.5	2.5	5.0	-0.1	2.2
Blood Red Count	1.4	13.3	20.7	-2.4	-4.5
Number of treatments/medications taken	1.4	2.5	3.1	-1.3	-1.8
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	2.7	-0.6	-1.6
Leg fat-free mass (right)	1.4	7.7	10.1	-3.2	-2.3
Average weekly spirits intake	1.3	1.6	3.1	-1.8	-0.3
Hair/balding pattern: Pattern 2	1.3	1.6	3.1	1.7	-0.4
Weight	1.3	6.2	8.9	-3.0	-1.9
Medication: Cholesterol lowering	1.3	2.0	3.1	-0.9	-1.8
Standing height	1.3	12.6	14.5	-3.8	-3.3
Supplements: Vitamin C	1.3	1.5	1.7	-1.2	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.6	3.1	-0.2	-1.8
Illnesses of father: None of the above (group 1)	1.3	1.6	1.7	-1.3	-1.2
Mother’s age at death	1.3	1.6	2.0	1.4	1.1
Irritable Bowel Disease (IBD)	1.2	2.9	5.7	0.3	2.4
Coronary Artery Disease (CAD)	1.2	1.5	2.5	-0.7	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	2.2	1.5	1.0
Father’s age at death	1.2	1.6	3.1	-1.8	-0.3
Hair/balding pattern: Pattern 4	1.2	2.8	5.3	-2.3	-0.6
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	2.6	0.2	1.6
Hip circumference	1.1	4.9	7.0	-2.6	-1.7
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	2.2	1.1	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	1.8	1.3	0.9
Diabetes (mother)	1.0	1.3	2.3	1.5	0.5
Maternal smoking around birth	1.0	1.4	2.6	0.5	1.6
Illnesses of mother	1.0	1.3	2.0	-1.4	-0.7
Pulse wave Arterial Stiffness index	1.0	1.1	2.0	-0.5	-1.4
Comparative body size at age 10	1.0	2.7	3.0	-1.5	-1.7
Worry too long after embarrassment	1.0	1.6	2.1	-1.1	-1.5
Heart disease (mother)	1.0	1.2	1.9	-0.7	-1.4
Had major operations	1.0	1.2	1.9	0.7	1.4
Back pain experienced in last month	1.0	1.4	1.6	-1.3	-1.1
Medication: Gliclazide	1.0	1.1	2.2	0.1	1.5
Smoking status: Current	1.0	1.7	3.3	1.8	0.2
Medication: Bendroflumethiazide	1.0	1.5	2.8	-0.4	-1.7
Body Mass Index (BMI) (2010)	0.9	1.3	2.3	-1.5	-0.4
Crohns Disease (2012)	0.9	1.4	2.8	0.0	1.7
Systolic Blood Pressure	0.9	4.6	5.7	-2.4	-1.9
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.8	-1.4	-0.5
Angina	0.9	1.1	1.2	-1.1	-1.0
Current tobacco smoking	0.9	1.4	2.8	1.7	0.2
Hayfever, allergic rhinitis or eczema	0.9	1.9	2.9	1.7	1.0
Qualifications: None of the above	0.9	2.0	3.9	-0.3	-2.0
Mouth/teeth dental problems	0.9	1.4	2.0	-1.4	-0.9
Diabetes (self-reported)	0.9	1.4	2.0	-0.9	1.4
Fluid intelligence score	0.9	1.8	3.0	0.8	1.7
Loud music exposure frequency	0.9	1.0	1.9	0.3	1.4
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.2	-0.2	1.5
Medication: Paracetamol	0.9	1.4	2.0	1.4	0.9
Mouth/teeth dental problems: Loose teeth	0.9	1.0	1.8	-1.3	-0.5
Medication: Allopurinol	0.9	1.2	2.2	-0.4	-1.5
Illnesses of father: High blood pressure	0.9	1.1	1.9	0.5	1.4
Alcohol drinker status: Never	0.9	1.1	1.2	0.9	1.1
Ovarian Cancer	0.8	1.1	2.1	0.2	1.5
Medication for hormone replacement therapy	0.8	0.8	1.0	-1.0	-0.8
Supplements: Zinc	0.8	0.9	1.0	-1.0	-0.9
Hand grip strength (right)	0.8	2.2	2.3	-1.5	-1.4
Trunk fat mass	0.8	3.3	3.8	-1.9	-1.7
Financial difficulties in last 2 years	0.8	1.1	2.0	-1.4	0.3
Noisy workplace	0.8	1.0	1.3	1.1	0.9
Prospective memory result	0.8	1.0	1.9	0.2	-1.4
Glaucoma (self-reported)	0.8	0.9	1.6	1.3	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	1.3	-1.1	0.8
Breast cancer (self-reported)	0.8	0.9	1.8	-1.4	-0.3
Alcohol drinker status: Previous	0.8	1.0	1.5	0.6	-1.2
Bipolar Disorder (2018)	0.7	1.0	1.2	0.9	1.1
Intelligence (Savage-Jansen 2018)	0.7	2.2	3.2	1.8	1.0
Medication: Metformin	0.7	1.0	1.1	-1.0	1.0
Impedance of leg (left)	0.7	3.3	5.8	2.4	1.0
Waist circumference	0.7	2.6	3.1	-1.8	-1.5
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	1.1	-1.1	-1.0
Alcohol intake versus 10 years previously	0.7	1.0	2.0	1.4	0.2
Number of live births	0.7	1.0	1.3	1.1	0.9
Pulse rate	0.7	1.2	2.3	0.3	1.5
Birth weight of first child	0.7	1.3	2.3	1.5	-0.6
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	2.5	-1.6	-0.5
Wheeze or whistling in the chest in last year	0.7	1.2	1.2	1.1	1.1
Angina (self-reported)	0.7	0.9	1.0	-1.0	-0.9
Migraine (self-reported)	0.7	0.9	1.2	-1.1	-0.7
Whole body fat mass	0.7	2.7	3.8	-2.0	-1.3
Comparative height size at age 10	0.7	4.1	5.8	-2.4	-1.6
Ever had bowel cancer screening	0.7	0.8	1.1	1.0	0.8
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.2	1.1	0.8
Fractured/broken bones in last 5 years	0.7	0.9	0.9	-0.9	-1.0
Diastolic blood pressure, automated reading	0.7	2.1	3.2	-1.0	-1.8
Basal cell carcinoma (self-reported)	0.7	0.8	1.4	1.2	0.4
Bipolar Disorder or Schizophrenia	0.6	1.5	1.7	1.3	1.1
Schizophrenia vs Biploar Disorder	0.6	0.7	1.3	1.2	0.4
Age at First Birth	0.6	0.8	0.9	-0.9	-0.9
Hypothyroidism (self reported)	0.6	1.3	2.5	-1.6	-0.4
Impedance of leg (right)	0.6	2.9	4.4	2.1	1.2
Average weekly fortified wine intake	0.6	0.7	1.2	0.4	1.1
Nervous feelings	0.6	1.1	1.8	1.3	0.7
Medication: Lansoprazole	0.6	0.7	1.3	-0.1	-1.2
Length of working week for main job	0.6	0.6	1.3	-1.1	-0.1
Birth weight	0.6	1.2	1.4	1.1	-1.2
Exposure to tobacco smoke outside home	0.6	0.9	1.6	-0.3	-1.3
Illnesses of father: Heart disease	0.6	0.8	1.3	-0.6	-1.1
Friendships satisfaction	0.6	0.7	1.2	0.4	1.1
Average weekly champagne plus white wine intake	0.6	0.9	1.4	-0.6	1.2
Financial situation satisfaction	0.6	0.8	1.3	0.4	1.1
Medication: Blood pressure	0.6	1.1	1.5	1.2	-0.8
Medication: Lisinopril	0.6	0.8	1.4	-0.3	-1.2
Number of operations (self-reported)	0.6	0.8	1.3	-0.6	-1.1
Ever depressed for a whole week	0.6	0.7	1.2	1.1	0.5
Cholesterol lowering medication	0.6	0.8	0.9	0.9	1.0
Verbal and Numeric Reasoning (VNR)	0.5	1.1	1.4	1.2	0.9
Heel T-Score	0.5	3.9	5.4	-1.6	-2.3
Height	0.5	9.6	10.8	-3.3	-2.9
Age when periods started (menarche)	0.5	1.1	2.2	-0.1	-1.5
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.1	0.4	1.0
Pulse wave peak to peak time	0.5	0.6	1.1	0.2	1.0
Leg fat mass (right)	0.5	2.0	3.2	-1.8	-0.9
Pulse rate, automated reading	0.5	1.6	1.7	1.3	1.2
Number of full sisters	0.5	0.6	0.9	1.0	0.5
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.8	-0.5	-0.9
Mood swings	0.5	1.0	1.4	-0.7	-1.2
Medication: Paracetamol	0.5	0.8	1.0	1.0	0.7
Medication: Atorvastatin	0.5	0.6	0.7	-0.8	-0.7
Risk taking	0.5	0.8	1.2	0.6	1.1
Ever had prostate specific antigen (PSA) test	0.5	0.5	0.8	-0.5	0.9
Pack years of smoking	0.5	0.7	1.4	-1.2	-0.1
Mean Putamen Volume	0.4	0.4	0.9	0.9	0.1
Fasting Glucose	0.4	0.5	0.5	0.7	0.7
Triglycerides	0.4	0.7	0.8	0.9	0.8
Frequency of depressed mood in last 2 weeks	0.4	0.5	0.8	0.9	0.5
Ever had hysterectomy (womb removed)	0.4	0.5	0.8	-0.3	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	1.7	-0.2	-1.3
High blood pressure	0.4	1.2	1.9	-0.7	-1.4
Multivitamins +/- minerals	0.4	0.5	0.7	0.4	0.9
Medication: Atenolol	0.4	0.5	0.8	-0.3	-0.9
Past tobacco smoking	0.4	0.8	1.4	-1.2	0.4
Happiness	0.4	0.5	0.6	0.7	0.8
Mouth/teeth dental problems: Dentures	0.4	0.6	1.1	1.0	0.4
Headache pain in last month	0.4	0.7	1.3	-0.3	-1.1
Age at first live birth	0.4	0.7	1.3	0.4	1.1
Shortness of breath walking on level ground	0.4	0.5	0.9	-0.2	-1.0
Neck or shoulder pain in last month	0.4	0.5	1.0	0.1	1.0
Mean time to correctly identify matches	0.4	0.7	1.4	-0.2	-1.2
Alcohol intake frequency.	0.4	1.0	1.8	1.3	-0.4
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.7	-0.3	-0.9
Hypertension (Self-reported)	0.4	1.1	1.8	-0.6	-1.4
Medication for cholesterol	0.4	0.7	1.4	-0.0	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	1.6	1.3	-0.1
Wears glasses or contact lenses	0.4	0.4	0.5	0.7	-0.6
Pain type(s) experienced in last month: Hip pain	0.4	0.6	1.1	1.0	0.2
Ever smoked	0.4	0.6	0.9	0.9	-0.6
Vascular/heart problems diagnosed by doctor	0.4	1.1	1.9	0.5	1.4
Leg fat mass (left)	0.4	1.6	2.5	-1.6	-0.8
Schizophrenia (2018)	0.3	0.7	1.0	1.0	0.6
Prostate Cancer	0.3	0.4	0.8	0.2	0.9
Schizophrenia (2014)	0.3	0.6	0.9	0.9	0.5
BMI	0.3	1.7	3.3	-1.8	-0.2
Waist Hip Ratio (WHR)	0.3	1.4	2.8	1.7	-0.2
Smoking Status	0.3	0.7	1.0	1.0	-0.7
Allergy or Eczema	0.3	0.9	1.5	1.2	0.5
Chronotype (morning person)	0.3	0.8	1.4	0.4	1.2
Pack years adult smoking proportion	0.3	0.4	0.7	-0.8	0.3
Townsend deprivation index at recruitment	0.3	0.5	0.6	0.8	0.6
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.3	-0.5	-0.5
Forced vital capacity (FVC)	0.3	1.3	2.3	-0.6	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.1	0.5	-1.1
Neuroticism score	0.3	0.7	1.1	-0.5	-1.1
Tense / ‘highly strung’	0.3	0.5	0.7	-0.9	-0.5
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.6	0.8	0.2
Qualifications: College or University degree	0.3	1.1	2.1	0.2	1.4
Medication: Blood pressure	0.3	0.5	0.7	-0.6	-0.8
Knee pain experienced in last month	0.3	0.5	0.7	-0.8	-0.6
Smoking status: Previous	0.3	0.5	1.0	0.3	-1.0
Qualifications: nursing, teaching	0.3	0.4	0.8	-0.9	-0.3
High cholesterol (Self-reported)	0.3	0.5	0.9	0.3	-0.9
Commuting to job workplace: Cycle	0.3	0.3	0.4	0.6	0.6
Depressed Affect (Nagel 2018)	0.2	0.5	0.8	-0.5	-0.9
Depression (Nagel 2018)	0.2	0.3	0.5	0.7	0.4
Alzheimer’s Disease (in father)	0.2	0.2	0.3	0.4	0.5
Rheumatoid Arthritis	0.2	0.2	0.4	-0.4	-0.6
Hand grip strength (left)	0.2	0.5	0.8	-0.4	-0.9
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.4	-0.7	0.1
Vitamin and mineral supplements	0.2	0.2	0.3	-0.5	-0.5
Qualifications: CSEs or equivalent	0.2	0.2	0.3	0.5	0.4
Supplements: Glucosamine	0.2	0.2	0.5	-0.1	0.7
Body mass index (BMI)	0.2	1.0	1.8	-1.3	-0.5
Had menopause	0.2	0.3	0.6	0.8	-0.1
Medication: Ramipril	0.2	0.3	0.5	0.3	-0.7
Worrier / anxious feelings	0.2	0.3	0.7	0.1	-0.8
Depression (self-reported)	0.2	0.2	0.2	-0.5	-0.4
Arm fat mass (right)	0.2	0.9	1.3	-1.2	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.5	0.7	0.4
Pulse wave reflection index	0.2	0.2	0.5	-0.1	-0.7
Medication: Amlodipine	0.2	0.2	0.4	-0.1	-0.7
High blood pressure (siblings)	0.2	0.3	0.4	-0.5	-0.6
Forced vital capacity (FVC), Best measure	0.2	0.9	1.0	-0.9	-1.0
Leg fat percentage (right)	0.2	0.6	0.9	-1.0	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.4	-0.6	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.5	-0.3	0.7
Health satisfaction	0.2	0.2	0.4	-0.2	0.6
Emphysema/chronic bronchitis	0.2	0.2	0.4	-0.1	0.6
Medication: Ibuprofen	0.2	0.2	0.3	0.2	-0.6
Suffer from ‘nerves’	0.2	0.3	0.5	-0.7	-0.4
Chest pain or discomfort	0.2	0.3	0.5	0.7	-0.2
Illnesses of siblings: Diabetes	0.2	0.3	0.6	0.1	-0.7
Average weekly red wine intake	0.2	0.2	0.4	-0.2	0.6
Arm fat mass (left)	0.2	1.0	1.5	-1.2	-0.7
Number of self-reported non-cancer illnesses	0.2	0.4	0.5	0.5	-0.7
Miserableness	0.2	0.4	0.8	0.0	-0.9
Commuting to job workplace: Public transport	0.2	0.3	0.4	-0.4	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.3	-0.4	-0.5
Supplements: Calcium	0.2	0.2	0.3	-0.3	-0.5
Neuroticism (Nagel 2018)	0.1	0.2	0.4	-0.1	-0.6
Worry (Nagel 2018)	0.1	0.1	0.3	0.5	0.1
Ulcerative Colitis (UC)	0.1	0.2	0.4	-0.1	0.6
Reaction Time	0.1	0.1	0.2	0.5	0.2
Bipolar Disorder (2011)	0.1	0.1	0.2	0.5	-0.1
HbA1C	0.1	0.1	0.2	-0.4	-0.0
LDL Cholesterol	0.1	0.2	0.2	0.5	-0.4
Neuroticism (2016)	0.1	0.2	0.3	0.3	0.5
Primary Biliary Cirrhosis	0.1	0.2	0.3	0.5	-0.4
Blood Platelet Count	0.1	1.5	1.7	1.2	1.3
Cardiovascular Disease	0.1	0.3	0.6	0.2	-0.7
Lung FEV1/FVC ratio	0.1	0.7	0.9	-1.0	-0.6
Lung FVC	0.1	0.7	1.3	0.4	-1.1
Neuroticism	0.1	0.3	0.3	-0.4	-0.6
Hair Pigment	0.1	3.8	5.8	-1.3	-2.4
Severe depression (siblings)	0.1	0.2	0.2	-0.3	0.5
Trunk fat percentage	0.1	0.5	0.9	-0.4	-0.9
Fed-up feelings	0.1	0.1	0.1	-0.4	-0.3
High blood pressure (mother)	0.1	0.2	0.3	-0.2	0.5
Alcohol usually taken with meals	0.1	0.1	0.1	-0.3	-0.4
Had other major operations	0.1	0.2	0.3	-0.6	-0.1
Heart attack	0.1	0.1	0.3	0.5	0.1
Pain all over the body in last month	0.1	0.1	0.1	-0.4	0.3
Medication: Simvastatin	0.1	0.1	0.3	0.5	-0.0
Illnesses of siblings	0.1	0.1	0.1	0.3	0.3
Time employed in main current job	0.1	0.1	0.2	-0.4	-0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.6	-0.3	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.3	-0.2	-0.5
Exposure to tobacco smoke at home	0.1	0.1	0.2	0.5	0.0
Body fat percentage	0.1	0.2	0.3	-0.5	-0.5
Eye problems/disorders: None of the above	0.1	0.1	0.1	0.4	-0.2
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	-0.4	-0.2
Medication: Omeprazole	0.1	0.1	0.3	0.5	0.0
Overall health rating	0.1	0.1	0.2	0.1	0.5
Family relationship satisfaction	0.1	0.1	0.2	0.4	0.1
Leg pain on walking	0.1	0.1	0.1	0.4	0.2
Medication: Aspirin	0.1	0.1	0.2	-0.5	-0.1
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	0.5	0.0
Long-standing illness, disability or infirmity	0.1	0.2	0.4	-0.7	0.1
Commuting to job workplace: Walk	0.1	0.1	0.1	0.2	0.4
Eye problems/disorders: Cataract	0.1	0.2	0.2	-0.3	-0.5
Mineral and other dietary supplements	0.1	0.1	0.2	-0.5	-0.2
Osteoarthritis (self-reported)	0.1	0.2	0.3	-0.6	0.1
Medication: Aspirin	0.1	0.1	0.2	-0.5	0.0
Eye problems/disorders: Glaucoma	0.1	0.2	0.2	0.4	-0.4
Leg fat percentage (left)	0.1	0.4	0.6	-0.8	-0.5
Average weekly beer plus cider intake	0.1	0.2	0.3	0.3	0.5
Unable to work because of sickness or disability	0.1	0.1	0.2	-0.0	-0.4
HDL Cholesterol	0.0	0.0	0.0	0.2	0.2
Lupus	0.0	0.1	0.1	0.3	0.0
Ulcerative Colitis	0.0	0.1	0.1	0.1	0.4
Tanning	0.0	0.1	0.2	-0.5	0.0
Diabetes (father)	0.0	0.0	0.1	-0.2	0.2
Stomach or abdominal pain in last month	0.0	0.0	0.1	-0.3	0.1
Number of incorrect matches in round	0.0	0.0	0.0	0.0	-0.2
Arm fat percentage (right)	0.0	0.1	0.1	0.3	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.1	0.3	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.1	0.1	0.2	-0.3
Medication: Seretide 50 evohaler	0.0	0.1	0.1	0.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.1	0.1	0.1	-0.3
Arm fat percentage (left)	0.0	0.0	0.0	0.1	0.1
Loneliness, isolation	0.0	0.1	0.1	0.3	0.0
Guilty feelings	0.0	0.0	0.0	-0.0	-0.2
Ever taken oral contraceptive pill	0.0	0.0	0.0	0.1	0.2
Irritability	0.0	0.1	0.1	-0.4	0.1
Pain experienced in last month	0.0	0.1	0.1	0.4	-0.0
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.1	0.3	-0.1
Heart disease (siblings)	0.0	0.0	0.1	-0.2	-0.2

Hub : Genes

LOC284751

Models

Trait associations