[Hub]/) : Traits : Trunk predicted mass :

chr7:90,624,416-93,160,671

Best TWAS P=1.24e-71 · Best GWAS P=3.1e-65 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CDK6 0.12 0.10 lasso 2 0.10 1.9e-12 16.86 16.9 7.2e-64 1.00 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex KRIT1 0.04 0.01 blup 318 0.02 1.2e-03 4.89 -6.2 5.8e-10 -0.23 0.60 0.02 TRUE
3 GTEx Adipose Subcutaneous GATAD1 0.21 0.14 enet 10 0.16 3.4e-13 8.55 -6.3 2.1e-10 -0.37 1.00 0.00 FALSE
4 GTEx Adipose Visceral Omentum GATAD1 0.12 0.08 lasso 5 0.06 7.5e-04 8.55 -8.7 4.9e-18 -0.46 0.82 0.06 FALSE
5 GTEx Adrenal Gland GATAD1 0.40 0.22 lasso 7 0.25 2.0e-09 8.55 -9.7 2.6e-22 -0.47 0.69 0.06 FALSE
6 GTEx Artery Aorta KRIT1 0.15 0.00 enet 24 0.03 1.3e-02 0.63 -7.6 2.2e-14 -0.28 0.12 0.05 FALSE
7 GTEx Artery Aorta GATAD1 0.09 0.08 enet 4 0.07 7.4e-05 8.55 -8.7 3.4e-18 -0.42 0.53 0.04 TRUE
8 GTEx Artery Coronary GATAD1 0.12 0.15 lasso 3 0.12 8.0e-05 8.40 -8.8 1.4e-18 -0.41 0.19 0.20 FALSE
9 GTEx Artery Tibial GATAD1 0.14 0.04 enet 17 0.04 4.1e-04 8.55 -8.2 1.7e-16 -0.38 0.70 0.10 FALSE
10 GTEx Artery Tibial AC000120.7 0.08 0.06 lasso 4 0.06 3.2e-05 4.72 -6.0 1.8e-09 -0.26 0.96 0.00 TRUE
11 GTEx Artery Tibial AC007566.10 0.13 0.04 lasso 5 0.00 3.1e-01 5.93 -7.0 1.7e-12 -0.15 0.08 0.03 FALSE
12 GTEx Brain Caudate basal ganglia GATAD1 0.21 0.09 lasso 4 0.08 2.3e-03 6.67 -9.7 2.0e-22 -0.43 0.08 0.20 FALSE
13 GTEx Brain Cortex AC000120.7 0.12 0.08 enet 16 0.07 7.0e-03 4.82 -6.7 1.7e-11 -0.42 0.14 0.05 TRUE
14 GTEx Breast Mammary Tissue (Female) AC007566.10 0.04 -0.01 lasso 2 0.01 2.0e-01 1.52 -8.3 9.5e-17 -0.37 0.02 0.24 FALSE
15 GTEx Cells Transformed fibroblasts GATAD1 0.23 0.20 lasso 4 0.22 1.4e-16 8.55 -11.3 1.2e-29 -0.58 0.99 0.01 FALSE
16 GTEx Colon Transverse GATAD1 0.13 0.00 enet 16 0.05 3.0e-03 8.55 -9.6 7.3e-22 -0.38 0.21 0.12 FALSE
17 GTEx Esophagus Mucosa GATAD1 0.16 0.05 enet 16 0.08 7.3e-06 8.55 -9.1 7.3e-20 -0.42 0.82 0.05 FALSE
18 GTEx Esophagus Muscularis GATAD1 0.18 0.10 enet 33 0.13 1.6e-08 8.55 -7.2 8.5e-13 -0.32 0.98 0.00 FALSE
19 GTEx Esophagus Muscularis FAM133B 0.07 0.01 enet 2 0.01 1.2e-01 -11.49 -11.6 5.1e-31 -0.46 0.06 0.45 FALSE
20 GTEx Lung GATAD1 0.15 0.12 lasso 2 0.11 1.1e-08 8.55 -8.5 1.4e-17 -0.42 0.99 0.00 FALSE
21 GTEx Muscle Skeletal CYP51A1 0.10 0.18 enet 21 0.17 5.0e-16 4.90 -5.6 2.7e-08 -0.24 1.00 0.00 FALSE
22 GTEx Muscle Skeletal PEX1 0.06 0.03 lasso 5 0.02 2.7e-03 6.84 7.5 9.4e-14 0.30 0.55 0.10 FALSE
23 GTEx Muscle Skeletal GATAD1 0.05 0.00 enet 13 0.01 2.4e-02 3.75 -8.4 4.6e-17 -0.38 0.48 0.02 FALSE
24 GTEx Nerve Tibial GATAD1 0.30 0.19 lasso 5 0.23 1.8e-16 8.55 -6.6 5.5e-11 -0.35 1.00 0.00 FALSE
25 GTEx Pancreas GATAD1 0.12 0.13 lasso 2 0.14 2.0e-06 8.55 -7.7 1.2e-14 -0.40 0.20 0.40 FALSE
26 GTEx Pituitary KRIT1 0.21 -0.01 enet 14 0.20 1.1e-05 0.37 -5.8 6.0e-09 -0.09 0.28 0.07 TRUE
27 GTEx Skin Not Sun Exposed Suprapubic GATAD1 0.22 0.27 lasso 4 0.26 1.1e-14 8.55 -8.7 2.8e-18 -0.42 1.00 0.00 FALSE
28 GTEx Skin Sun Exposed Lower leg PEX1 0.18 0.06 enet 41 0.03 1.5e-03 -9.19 -9.5 3.1e-21 -0.39 0.20 0.18 FALSE
29 GTEx Skin Sun Exposed Lower leg GATAD1 0.30 0.10 enet 14 0.16 7.0e-13 8.55 -8.4 3.5e-17 -0.39 1.00 0.00 FALSE
30 GTEx Spleen PEX1 0.18 0.00 enet 38 0.05 2.4e-02 4.94 -8.7 4.9e-18 -0.32 0.08 0.06 FALSE
31 GTEx Spleen AC000120.7 0.10 0.07 lasso 5 0.04 3.9e-02 5.07 -5.2 1.5e-07 -0.23 0.15 0.08 TRUE
32 GTEx Stomach GATAD1 0.30 0.13 lasso 5 0.15 8.6e-08 8.55 -8.8 8.8e-19 -0.46 0.98 0.00 FALSE
33 GTEx Testis CDK6 0.10 0.10 lasso 3 0.09 8.0e-05 16.97 -17.9 1.2e-71 -0.92 0.03 0.96 TRUE
34 GTEx Thyroid GATAD1 0.18 0.06 lasso 4 0.06 3.3e-05 8.55 -8.4 5.7e-17 -0.43 0.94 0.04 FALSE
35 METSIM Adipose GATAD1 0.10 0.05 lasso 7 0.06 9.4e-10 3.75 -6.6 4.5e-11 -0.40 1.00 0.00 FALSE
36 ROSMAP Brain Pre-frontal Cortex ANKIB1 0.03 0.03 enet 8 0.03 2.6e-04 4.97 -5.2 2.1e-07 -0.28 0.70 0.01 FALSE
37 ROSMAP Brain Pre-frontal Cortex KRIT1 0.04 0.03 bslmm 311 0.01 9.0e-03 4.96 8.9 5.9e-19 0.49 0.75 0.05 FALSE
38 ROSMAP Brain Pre-frontal Cortex MTERF 0.04 0.00 blup 375 0.02 7.5e-04 2.09 5.6 2.6e-08 0.21 0.09 0.30 TRUE
39 ROSMAP Brain Pre-frontal Cortex GATAD1 0.17 0.15 lasso 4 0.16 6.0e-20 8.42 -8.7 3.1e-18 -0.43 1.00 0.00 TRUE
40 YFS Blood CYP51A1 0.03 0.06 blup 288 0.05 1.2e-16 4.92 -6.6 4.2e-11 -0.31 1.00 0.00 FALSE
41 YFS Blood GATAD1 0.01 0.01 blup 297 0.01 5.1e-04 8.55 -11.2 6.9e-29 -0.55 0.73 0.10 FALSE
42 The Cancer Genome Atlas Breast Invasive Carcinoma GATAD1 0.06 0.04 lasso 6 0.04 2.2e-09 8.17 -7.5 7.5e-14 -0.31 0.83 0.17 FALSE
43 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CYP51A1 0.07 0.04 lasso 2 0.04 4.3e-05 4.97 -5.2 2.0e-07 -0.27 0.04 0.94 FALSE
44 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GATAD1 0.04 0.04 lasso 2 0.03 2.8e-04 8.17 -7.9 3.3e-15 -0.36 0.14 0.17 FALSE
45 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C7orf64 0.06 0.02 blup 36 0.02 6.0e-02 7.04 6.1 9.3e-10 0.22 0.04 0.05 FALSE