Best TWAS P=2.12e-16 · Best GWAS P=4.14e-17 conditioned to 0.251
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | TMEM9B | 0.12 | 0.03 | enet | 18 | 0.06 | 2.8e-04 | 6.70 | 5.2 | 2.4e-07 | -0.15 | 0.01 | 0.84 | FALSE |
| 2 | GTEx | Brain Cortex | RP11-152H18.3 | 0.41 | 0.04 | enet | 25 | 0.11 | 7.6e-04 | 4.02 | -6.1 | 8.4e-10 | 0.03 | 0.05 | 0.62 | TRUE |
| 3 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | 7.75 | 8.0 | 9.0e-16 | -0.86 | 0.04 | 0.77 | FALSE |
| 4 | GTEx | Testis | SBF2 | 0.10 | 0.01 | lasso | 5 | 0.02 | 5.0e-02 | 7.25 | -7.7 | 1.2e-14 | 0.82 | 0.07 | 0.82 | FALSE |
| 5 | NTR | Blood | ADM | 0.04 | 0.04 | enet | 13 | 0.04 | 1.6e-13 | 7.71 | -8.2 | 2.1e-16 | 0.88 | 0.09 | 0.91 | TRUE |
| 6 | NTR | Blood | WEE1 | 0.02 | 0.00 | bslmm | 367 | 0.00 | 1.0e-02 | 0.42 | -6.1 | 8.1e-10 | 0.33 | 0.10 | 0.20 | FALSE |
| 7 | ROSMAP | Brain Pre-frontal Cortex | SBF2-AS1 | 0.03 | 0.00 | bslmm | 362 | 0.01 | 4.4e-03 | -1.72 | 7.2 | 8.4e-13 | -0.59 | 0.04 | 0.64 | FALSE |
| 8 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | 7.91 | -8.0 | 1.9e-15 | 0.85 | 0.10 | 0.90 | FALSE |
| 9 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF143 | 0.02 | 0.02 | lasso | 2 | 0.02 | 4.5e-03 | 6.45 | -6.6 | 4.7e-11 | 0.07 | 0.01 | 0.94 | TRUE |