[Hub]/) : Traits : Trunk predicted mass :

chr14:24,039,559-25,605,046

Best TWAS P=7.44e-15 · Best GWAS P=1.99e-14 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous KHNYN 0.30 0.14 lasso 2 0.14 7.1e-12 5.1 5.4 8.4e-08 0.09 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous ADCY4 0.08 0.04 lasso 3 0.03 3.3e-03 5.1 5.4 5.6e-08 0.62 0.20 0.27 FALSE
3 GTEx Adipose Subcutaneous CBLN3 0.65 0.39 lasso 23 0.37 6.1e-32 5.1 -5.1 2.9e-07 -0.10 1.00 0.00 FALSE
4 GTEx Adipose Subcutaneous LTB4R 0.14 0.12 lasso 3 0.12 1.3e-09 5.1 -5.2 2.4e-07 -0.61 0.92 0.08 FALSE
5 GTEx Breast Mammary Tissue LTB4R 0.30 0.18 lasso 4 0.16 2.3e-08 5.3 -5.3 1.2e-07 -0.63 0.78 0.21 TRUE
6 GTEx Breast Mammary Tissue (Female) CBLN3 0.42 0.20 lasso 4 0.28 5.9e-09 5.1 -5.2 1.8e-07 -0.08 0.84 0.02 FALSE
7 GTEx Heart Atrial Appendage ADCY4 0.28 0.14 lasso 4 0.10 2.1e-05 7.1 6.1 9.5e-10 0.48 0.09 0.80 FALSE
8 GTEx Heart Atrial Appendage CBLN3 0.58 0.40 lasso 5 0.38 2.3e-18 5.1 -5.1 2.9e-07 -0.11 1.00 0.00 FALSE
9 GTEx Heart Left Ventricle CBLN3 0.35 0.23 lasso 8 0.21 1.5e-11 5.1 -5.5 4.6e-08 -0.16 1.00 0.00 TRUE
10 GTEx Lung KHNYN 0.14 0.08 lasso 5 0.05 9.7e-05 4.7 5.2 2.2e-07 0.08 0.66 0.01 FALSE
11 GTEx Lung LTB4R 0.19 0.15 lasso 6 0.12 2.0e-09 5.1 -5.6 1.9e-08 -0.66 0.99 0.01 FALSE
12 GTEx Muscle Skeletal CBLN3 0.14 0.13 enet 7 0.13 4.8e-13 5.1 -5.7 1.5e-08 -0.13 1.00 0.00 FALSE
13 GTEx Nerve Tibial KHNYN 0.34 0.10 lasso 8 0.15 1.6e-10 4.7 5.3 9.9e-08 0.10 1.00 0.00 TRUE
14 GTEx Ovary CBLN3 0.62 0.38 lasso 19 0.39 1.2e-10 5.1 -5.2 2.1e-07 -0.10 0.96 0.00 FALSE
15 GTEx Spleen NFATC4 0.45 0.00 enet 24 0.00 2.5e-01 5.1 -6.3 3.5e-10 -0.22 0.07 0.06 TRUE
16 GTEx Thyroid ADCY4 0.13 0.13 lasso 6 0.09 1.0e-07 4.2 5.6 1.8e-08 0.51 0.36 0.64 FALSE
17 METSIM Adipose ADCY4 0.07 0.03 lasso 5 0.03 2.2e-05 7.3 7.8 7.4e-15 0.71 0.04 0.96 TRUE
18 METSIM Adipose RABGGTA 0.10 0.06 lasso 9 0.08 5.5e-12 5.7 5.3 9.3e-08 0.62 0.99 0.01 FALSE
19 YFS Blood KHNYN 0.36 0.20 enet 50 0.29 1.2e-96 4.5 5.4 5.8e-08 0.14 1.00 0.00 FALSE
20 The Cancer Genome Atlas Bladder Urothelial Carcinoma ADCY4 0.03 0.01 blup 75 0.03 1.1e-03 4.8 6.0 2.3e-09 0.71 0.05 0.72 FALSE
21 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CBLN3 0.34 0.15 lasso 5 0.14 2.4e-07 5.1 -5.3 1.1e-07 -0.17 0.34 0.63 FALSE
22 The Cancer Genome Atlas Colon Adenocarcinoma ADCY4 0.07 0.02 lasso 4 0.03 4.7e-03 4.9 5.8 5.4e-09 0.70 0.03 0.76 TRUE
23 The Cancer Genome Atlas Colon Adenocarcinoma CBLN3 0.24 0.14 enet 8 0.13 4.0e-08 5.1 -5.5 3.3e-08 -0.14 0.35 0.65 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma ADCY4 0.06 0.06 lasso 6 0.09 3.0e-10 6.5 7.5 6.0e-14 0.75 0.06 0.94 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma ADCY4 0.07 0.09 lasso 3 0.08 4.4e-10 5.3 6.6 4.8e-11 0.73 0.88 0.12 FALSE
26 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LTB4R 0.16 0.05 blup 73 0.08 4.9e-04 3.6 -5.7 1.6e-08 -0.70 0.03 0.56 FALSE
27 The Cancer Genome Atlas Stomach Adenocarcinoma CBLN3 0.30 0.26 lasso 1 0.24 1.4e-17 5.1 -5.1 2.9e-07 -0.11 0.34 0.66 FALSE
28 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R 0.04 0.01 blup 73 0.01 4.2e-02 6.1 -5.9 3.8e-09 -0.63 0.01 0.46 FALSE
29 The Cancer Genome Atlas Stomach Adenocarcinoma LTB4R2 0.04 0.04 lasso 1 0.02 2.5e-02 6.1 -6.1 9.9e-10 -0.70 0.04 0.52 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma LTB4R 0.08 0.05 lasso 8 0.05 1.7e-05 4.8 -5.2 2.1e-07 -0.58 0.63 0.16 FALSE