[Hub]/) : Traits : Wheeze or whistling in the chest in last year : →

chr2:102,118,712-103,686,111

Best TWAS P=4.28e-31 · Best GWAS P=1.34e-24 conditioned to 0.0362

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Colon Transverse	IL18R1	0.14	0.00	enet	41	0.00	2.1e-01	2.99	7.0	1.8e-12	-0.33	0.07	0.09	FALSE
2	GTEx	Whole Blood	IL18R1	0.06	0.00	enet	14	0.01	2.1e-02	-8.83	5.2	2.1e-07	-0.51	0.14	0.23	FALSE
3	ROSMAP	Brain Pre-frontal Cortex	IL1RL2	0.08	0.02	enet	33	0.03	2.3e-04	4.42	-5.7	1.3e-08	0.27	0.17	0.17	FALSE
4	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IL1RL1	0.04	0.03	lasso	7	0.03	8.1e-04	-8.84	-9.5	3.2e-21	0.67	0.15	0.46	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL18R1	0.05	0.01	blup	108	0.03	1.8e-07	-8.80	5.9	2.9e-09	-0.43	0.82	0.16	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	IL1RL1	0.02	0.01	blup	78	0.01	1.5e-03	9.46	-9.9	4.5e-23	0.61	0.04	0.77	FALSE
7	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IL1RL1	0.04	0.04	lasso	8	0.04	1.7e-05	-9.75	-10.7	7.3e-27	0.78	0.01	0.98	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL18R1	0.06	0.01	blup	108	0.04	2.6e-05	-0.98	-5.1	3.0e-07	0.21	0.02	0.85	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL18RAP	0.03	0.02	blup	94	0.02	1.2e-03	-8.80	9.4	8.2e-21	-0.71	0.00	0.92	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL1	0.08	0.08	enet	9	0.08	1.2e-09	-9.74	-11.1	9.3e-29	0.71	0.00	1.00	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IL1RL2	0.04	0.04	enet	5	0.03	1.9e-04	-7.98	-8.2	2.9e-16	0.39	0.06	0.41	FALSE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IL1RL1	0.18	0.06	blup	78	0.15	3.7e-09	9.46	-11.5	1.4e-30	0.64	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Lung Adenocarcinoma	IL1RL1	0.03	0.01	blup	78	0.02	4.7e-03	-9.59	-11.6	4.3e-31	0.77	0.01	0.94	TRUE
14	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IL1RL1	0.19	0.05	blup	78	0.10	7.1e-05	9.54	-10.8	3.9e-27	0.68	0.05	0.86	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	IL1R1	0.36	0.19	enet	28	0.23	1.1e-23	-6.18	5.1	2.7e-07	-0.40	0.10	0.90	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	IL1RL1	0.05	0.03	enet	6	0.03	9.7e-04	-9.74	-9.9	2.7e-23	0.66	0.01	0.99	FALSE