Hub : Genes

KIFAP3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0770 0.0260 1.8e-06 0.064 0.049 0.052 0.051 0.057 2.8e-08 1.2e-06 6.1e-07 6.7e-07 1.8e-07
2 GTEx Artery Aorta 0.1400 0.0490 2.8e-04 0.136 NA 0.081 NA 0.101 6.4e-08 NA 3.1e-05 NA 3.5e-06
3 GTEx Artery Tibial 0.2000 0.0466 3.7e-10 0.120 NA 0.183 NA 0.199 1.3e-09 NA 2.7e-14 NA 1.6e-15
4 GTEx Cells Transformed fibroblasts 0.1410 0.0400 4.0e-08 0.045 NA 0.118 NA 0.129 2.5e-04 NA 3.7e-09 NA 7.0e-10
5 GTEx Esophagus Mucosa 0.1800 0.0510 3.1e-07 0.106 NA 0.106 NA 0.121 1.5e-07 NA 1.5e-07 NA 1.9e-08
6 GTEx Muscle Skeletal 0.0461 0.0213 6.2e-03 0.017 NA 0.004 NA 0.008 8.0e-03 NA 1.3e-01 NA 5.0e-02
7 TCGA Colon Adenocarcinoma 0.0660 0.0360 4.6e-03 0.035 0.035 0.041 NA 0.063 4.3e-03 3.9e-03 2.1e-03 NA 1.6e-04
8 TCGA Prostate Adenocarcinoma 0.0441 0.0237 4.0e-04 0.010 0.031 0.015 NA 0.021 3.0e-02 3.0e-04 8.5e-03 NA 2.6e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.0 1.6 5.9 -1.0 0.8 0.3 -2.4 0.6 0.1 -1.7 1.5
Bipolar Disorder or Schizophrenia 0.8 1.8 7.3 0.1 0.9 1.1 -2.7 0.2 -0.1 -1.3 1.9
Depressed Affect (Nagel 2018) 1.0 2.2 4.1 -1.8 -1.9 -2.0 -0.3 -2.0 1.4 0.2 0.6
Depression (Nagel 2018) 0.4 0.6 1.3 -1.0 -1.0 -0.8 0.4 -1.1 0.6 0.4 0.1
Intelligence (Savage-Jansen 2018) 0.5 1.6 2.9 -1.2 -1.0 -1.6 -1.0 -1.2 1.7 -0.8 1.3
Neuroticism (Nagel 2018) 0.3 0.6 1.3 -1.0 -0.7 -0.6 -0.8 -1.1 0.9 0.5 0.5
Schizophrenia (2018) 0.4 0.8 2.3 1.0 0.6 1.1 -1.5 -0.2 -0.2 -0.3 1.2
Schizophrenia vs Biploar Disorder 0.3 0.4 2.4 -0.3 0.2 0.1 -0.6 -0.2 -0.0 -0.3 1.6
Worry (Nagel 2018) 0.1 0.3 1.7 -0.2 0.5 0.5 -1.3 0.1 -0.2 -0.2 0.3
Alzheimer’s Disease (in mother) 0.7 0.9 2.9 -1.1 0.0 -0.6 -1.7 -0.5 1.0 -0.4 1.1
Alzheimer’s Disease (in father) 0.9 1.0 4.2 -0.9 -0.4 -0.4 0.1 -0.9 2.0 1.3 0.0
Alzheimer’s Disease (including proxy) 0.3 0.4 1.1 -0.5 0.7 0.3 -1.0 0.2 1.1 0.0 0.7
Crohns Disease (2017) 0.8 1.7 4.9 2.2 -1.4 -0.1 1.9 -0.8 -1.0 0.9 -0.6
Irritable Bowel Disease (IBD) 1.6 3.9 9.7 3.1 -0.6 0.7 2.7 -0.0 -1.9 2.3 -2.1
Ulcerative Colitis (UC) 2.1 3.9 9.4 2.6 0.2 1.1 2.1 0.6 -1.7 3.1 -2.5
Major Depression (MDD) 1.3 1.6 3.1 -1.8 -0.7 -0.6 -1.3 -1.4 1.5 1.3 1.2
Reaction Time 0.1 0.2 0.5 -0.6 0.0 0.3 -0.6 0.2 0.5 -0.7 0.5
Verbal and Numeric Reasoning (VNR) 0.3 0.7 2.1 -0.3 -1.3 -1.5 0.3 -1.1 0.8 -0.1 0.3
Breast Cancer 0.6 1.5 3.9 -0.6 -1.8 -1.5 0.6 -2.0 0.7 -0.1 1.0
Ovarian Cancer 0.6 0.8 1.2 0.9 0.7 0.9 1.1 0.8 -0.9 1.0 -1.0
Prostate Cancer 0.2 0.2 0.7 -0.0 0.0 -0.1 0.6 0.2 -0.5 0.9 -0.7
Age at First Birth 0.4 0.5 1.6 0.1 -0.8 -0.2 0.9 -0.3 -0.2 1.2 -1.0
Bipolar Disorder (2011) 1.1 1.1 2.5 -0.3 1.6 1.1 -1.3 1.5 -0.7 0.1 -0.4
Body Mass Index (BMI) (2010) 0.3 0.4 0.8 -0.9 -0.3 -0.6 -0.5 -0.9 0.8 0.7 -0.1
Coronary Artery Disease (CAD) 0.4 0.5 2.2 -0.2 1.5 1.1 -0.1 0.7 0.0 0.2 0.1
Crohns Disease (2012) 0.5 0.8 2.6 0.9 -1.6 -0.6 0.7 -0.9 -0.2 -1.1 0.7
Mean Putamen Volume 0.5 0.5 1.4 0.9 -0.6 0.4 0.5 -0.0 -1.1 -1.2 -0.0
Fasting Glucose 0.8 0.9 2.2 -0.1 -0.4 -1.5 -1.1 -1.1 1.3 -0.5 0.6
HbA1C 0.2 0.3 1.1 0.4 0.4 -0.1 0.7 -0.1 0.3 1.1 -0.2
HDL Cholesterol 0.5 0.9 2.3 -0.3 1.5 1.2 -0.6 1.5 -0.5 -0.7 -0.0
LDL Cholesterol 0.3 0.4 1.4 -1.2 0.6 -0.1 -0.9 0.2 0.2 0.1 0.8
Lupus 0.4 0.6 1.6 -0.0 0.9 0.6 -1.0 0.4 -0.4 -1.2 0.8
Neuroticism (2016) 1.5 2.2 4.3 -2.0 -1.8 -2.0 -0.7 -2.1 1.0 0.7 0.2
Primary Biliary Cirrhosis 1.0 1.4 6.0 -1.3 0.5 0.2 -2.4 -0.1 0.6 -1.2 1.1
Rheumatoid Arthritis 0.2 0.3 1.0 -0.9 -0.5 -1.0 -0.1 -0.5 0.4 -0.5 -0.1
Schizophrenia (2014) 0.6 1.4 4.6 0.2 0.6 0.8 -2.2 -0.0 0.2 -1.1 2.0
Triglycerides 0.7 1.1 4.0 -1.0 -0.0 -0.7 -0.9 -0.8 2.0 1.0 0.7
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.7 -0.2 0.9 0.4 -0.4 0.7 -0.5 -0.2 0.1
Ulcerative Colitis 1.2 1.7 4.3 2.1 0.3 1.0 1.2 0.6 -1.9 1.3 -1.2
Blood Eosinophil Count 0.8 6.0 13.8 2.1 2.8 3.7 1.5 3.0 -3.2 0.0 -0.5
Blood Platelet Count 0.2 1.7 4.4 1.3 1.5 2.1 -0.9 1.3 -0.2 -1.5 0.8
Blood Red Count 0.3 3.3 7.6 -1.6 -2.0 -2.5 -1.2 -2.8 0.8 -1.2 1.6
Blood White Count 0.3 2.4 7.2 1.8 -2.3 -0.7 2.7 -1.6 -0.3 0.3 -0.3
Heel T-Score 0.3 2.7 14.1 0.5 0.4 0.3 -3.8 -0.6 2.1 1.4 0.4
BMI 0.1 0.7 3.4 -0.6 -0.4 -0.7 -0.1 -0.2 -0.3 -1.9 1.0
Height 0.3 4.9 19.7 1.7 -1.5 -0.5 2.0 0.4 0.8 3.1 -4.4
Waist Hip Ratio (WHR) 1.9 8.5 31.2 -3.4 -0.9 -2.0 -5.6 -0.8 3.7 2.2 -1.1
Systolic Blood Pressure 0.2 0.9 2.0 -0.4 1.4 0.9 0.0 1.1 -0.9 1.0 -1.2
Smoking Status 0.6 1.3 2.7 -1.0 -0.8 -1.1 -0.3 -1.1 1.3 1.6 -1.4
Allergy or Eczema 0.6 1.6 4.8 -0.8 2.2 1.4 -1.3 1.2 0.3 -1.2 0.9
Cardiovascular Disease 0.4 1.2 2.8 0.1 1.5 0.9 0.1 1.7 -1.6 -1.1 -0.5
Hypothyroidism (self reported) 1.0 2.2 7.7 0.5 2.8 2.2 0.1 1.9 -0.5 0.8 -0.5
Respiratory disease 0.5 1.2 2.1 -1.2 -0.4 -1.0 -1.4 -1.0 1.4 -0.7 1.2
Type 2 Diabetes (T2D) (2018) 0.4 0.8 2.6 -1.6 0.7 -0.3 -1.0 0.5 1.2 -0.7 -0.0
Lung FEV1/FVC ratio 0.1 0.6 1.5 0.7 0.1 0.9 0.6 1.2 -1.1 -0.6 -0.2
Lung FVC 0.5 2.8 6.5 0.4 2.1 1.5 -2.5 2.5 -0.5 -1.5 0.2
Neuroticism 0.3 0.6 1.8 -0.6 -1.0 -0.7 0.2 -1.3 0.8 0.7 0.0
Chronotype (morning person) 0.3 0.7 1.7 1.3 0.0 0.6 0.9 0.1 -1.3 -0.8 0.3
Hair Pigment 0.0 1.3 3.8 1.7 -0.4 0.2 -0.1 0.8 -1.6 0.5 -2.0
Tanning 0.1 1.1 5.5 1.0 -0.6 -0.6 2.3 -0.0 -0.4 0.3 -1.3
Hand grip strength (left) 0.1 0.2 0.5 -0.4 -0.1 -0.6 0.1 -0.2 0.6 -0.3 0.7
Number of treatments/medications taken 0.2 0.4 1.0 -0.8 0.9 0.5 0.4 0.6 1.0 0.3 -0.3
Average weekly spirits intake 1.7 2.1 5.5 0.0 1.4 1.5 1.0 2.4 -1.2 1.1 -2.0
Sensitivity / hurt feelings 0.6 1.1 3.1 -0.9 -0.8 -0.9 -0.6 -1.8 1.5 0.7 0.8
Frequency of depressed mood in last 2 weeks 0.2 0.3 0.6 -0.2 0.6 0.8 0.8 0.5 -0.1 0.5 -0.2
Hearing difficulty/problems: Yes 0.3 0.5 1.2 -0.9 -0.7 -1.1 -0.0 -0.6 1.1 0.1 0.6
Relative age of first facial hair 1.6 3.3 6.4 2.2 0.9 2.1 2.5 1.4 -1.5 2.0 -1.3
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 1.6 0.9 1.0 1.3 0.8 1.1 -0.2 1.2 -1.0
Ever used hormone-replacement therapy (HRT) 1.8 2.4 7.1 -0.6 2.1 1.4 -2.7 1.2 -0.1 -1.3 1.3
Ever had hysterectomy (womb removed) 4.3 4.8 10.8 -3.3 -1.0 -2.0 -3.2 -2.0 2.6 0.6 1.4
Systolic blood pressure, automated reading 0.3 0.8 1.4 0.4 1.1 0.7 1.1 1.2 -0.8 0.2 -1.2
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 0.6 0.1 0.6 0.8 0.4 0.6 0.7 0.5 -0.1
Angina 1.3 1.6 3.6 0.1 1.9 1.5 0.0 1.7 -1.3 -1.3 1.1
Medication for hormone replacement therapy 0.4 0.5 1.5 -0.4 1.2 0.8 0.3 0.9 0.5 0.4 -0.3
Vitamin and mineral supplements 1.0 1.4 3.3 1.3 1.2 1.2 0.3 1.3 -1.1 0.4 -1.8
Supplements: Zinc 0.8 0.9 2.0 1.1 -1.4 -0.2 1.2 -0.8 -0.7 1.0 -0.6
Medication: Co-codamol 0.9 1.0 3.8 -0.2 0.7 0.3 -1.9 0.8 0.1 -1.6 0.8
Medication: Metformin 0.4 0.5 1.2 -0.6 0.1 -0.0 0.9 0.7 1.1 1.1 -0.6
Diabetes (father) 0.5 0.6 1.8 -1.0 -0.2 -0.6 -1.3 -0.5 0.9 -0.9 0.4
Diabetes (mother) 0.2 0.2 0.7 0.6 -0.7 -0.8 -0.3 0.3 -0.3 -0.3 -0.2
Severe depression (siblings) 0.6 0.7 1.4 -1.2 1.2 0.5 -0.9 0.2 1.0 0.8 0.2
Pack years adult smoking proportion 0.1 0.2 0.6 -0.4 0.4 0.3 -0.1 0.4 0.3 0.8 -0.2
Impedance of leg (right) 0.9 4.3 15.4 -0.7 3.9 2.6 -1.6 2.0 -0.1 2.1 -0.6
Leg fat-free mass (left) 0.6 3.0 10.8 0.5 -3.3 -2.4 1.5 -2.1 0.5 -0.5 -0.2
Trunk fat percentage 0.2 0.6 2.2 0.4 0.8 0.5 1.5 0.4 -1.1 -0.8 -0.1
Hand grip strength (right) 0.1 0.4 1.4 -0.2 0.6 -0.3 -0.3 0.1 0.2 -0.9 1.2
Townsend deprivation index at recruitment 0.2 0.3 0.9 -0.5 0.9 0.0 -0.1 0.1 -0.2 0.7 -0.7
Current tobacco smoking 0.7 1.2 2.9 0.7 0.9 1.5 0.1 0.9 -0.6 1.7 -1.5
Average weekly fortified wine intake 0.4 0.5 1.2 0.4 1.1 0.8 -0.1 0.8 -0.7 0.3 -0.7
Maternal smoking around birth 1.0 1.4 5.7 -1.0 1.1 -0.0 -0.3 0.7 -0.3 2.4 -1.6
Fed-up feelings 0.7 1.3 3.3 -1.0 -1.7 -1.6 -0.1 -1.8 0.7 0.4 0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 1.1 -0.3 -1.0 -0.8 1.1 -0.8 0.0 0.0 -0.4
Relative age voice broke 1.4 2.1 4.2 1.6 2.0 2.0 -0.4 1.6 -1.8 -0.1 0.6
Taking other prescription medications 0.4 0.7 3.1 -1.0 -0.2 -0.7 0.3 -0.3 1.8 0.7 -0.5
Age when periods started (menarche) 1.5 3.7 6.6 2.2 1.6 2.2 1.5 2.6 -2.4 -0.6 -1.2
Bilateral oophorectomy (both ovaries removed) 5.0 5.8 11.2 -2.8 -2.0 -2.8 -2.1 -2.9 3.3 0.8 1.4
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.2 7.0 -1.0 -0.1 -0.8 -2.6 -1.4 1.6 -0.5 2.1
Tinnitus: Yes, but not now, but have in the past 0.6 0.7 1.8 -1.4 -0.1 -0.4 -0.4 -1.0 1.1 0.5 0.9
Qualifications: CSEs or equivalent 1.2 1.5 3.4 -0.7 -1.5 -1.6 -0.5 -1.8 1.5 0.3 1.1
Serious illness, injury or assault to yourself 1.7 2.1 5.8 0.8 0.7 1.2 1.4 1.1 -0.3 2.4 -2.2
High blood pressure 0.7 1.9 3.7 1.0 1.9 1.8 0.8 1.8 -1.2 -0.0 -1.4
Hayfever, allergic rhinitis or eczema 0.1 0.2 0.8 -0.2 0.8 0.9 -0.1 0.4 0.4 -0.3 0.2
Multivitamins +/- minerals 0.4 0.5 1.2 -1.1 -0.7 -0.7 -0.3 -0.3 0.9 -0.1 0.7
Stomach or abdominal pain in last month 1.6 2.0 2.9 1.4 1.0 1.4 1.3 1.7 -1.3 1.3 -1.7
Supplements: Glucosamine 0.6 0.7 2.1 -0.7 -0.8 -1.0 -0.4 -0.4 -0.1 -1.5 1.1
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 3.5 -0.1 0.1 0.3 1.1 -0.1 -0.6 1.9 -0.8
Medication: Atenolol 0.8 1.0 2.1 -0.1 1.4 1.3 -0.1 1.5 -1.3 0.1 -0.9
Medication: Levothyroxine sodium 1.7 2.9 8.2 0.7 2.9 2.5 0.3 2.7 -0.8 0.4 -0.7
Sitting height 0.2 1.1 2.5 -0.5 -0.4 -1.1 -1.6 -1.3 1.6 -0.4 0.5
Chronic bronchitis/emphysema (father) 0.4 0.5 1.5 -1.2 0.9 0.3 -0.6 0.1 0.5 0.4 0.7
High blood pressure (mother) 0.7 1.0 2.1 1.1 0.3 0.9 1.5 0.9 -1.0 -1.2 -0.2
Body mass index (BMI) 0.2 0.9 4.8 0.3 -0.7 -0.7 2.2 -0.4 -0.8 -0.5 -0.6
Impedance of leg (left) 0.8 3.7 13.0 -0.5 3.6 2.3 -2.1 1.9 0.0 1.7 -0.1
Leg predicted mass (left) 0.6 3.0 10.8 0.5 -3.3 -2.4 1.5 -2.2 0.5 -0.6 -0.1
Trunk fat mass 0.1 0.5 2.4 0.5 0.2 0.0 1.5 0.2 -0.8 -0.7 -0.4
Waist circumference 0.2 0.7 1.7 -0.8 -0.9 -1.3 0.2 -0.7 1.0 0.5 -0.9
Number of incorrect matches in round 1.6 2.7 7.9 -0.1 1.0 0.9 1.6 1.4 -0.5 2.6 -2.8
Past tobacco smoking 1.3 2.4 4.4 1.8 1.1 1.5 -0.1 1.5 -1.9 -2.1 1.4
Alcohol usually taken with meals 0.1 0.2 1.3 0.6 0.0 0.1 -0.2 -0.0 0.0 -1.2 0.2
Nervous feelings 0.4 0.8 1.7 0.9 1.1 1.3 -0.6 0.8 -0.2 1.2 -0.5
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 0.9 -1.0 0.0 -0.3 -0.7 -0.8 0.7 0.0 0.9
Hearing difficulty/problems with background noise 1.3 2.1 5.3 -1.2 -2.2 -2.3 0.9 -1.7 1.0 -0.0 0.5
Hair/balding pattern: Pattern 2 3.7 4.7 28.3 1.7 -1.5 -0.4 5.3 -0.3 -0.9 0.7 -1.7
Had menopause 0.6 0.7 2.2 -0.6 1.5 0.7 -0.7 0.5 0.5 -1.0 0.8
Had other major operations 0.6 0.8 1.7 0.7 1.3 1.2 -0.9 1.3 -0.1 0.1 -0.3
Forced vital capacity (FVC) 0.2 0.9 5.6 0.0 -0.4 -0.4 -2.4 -0.4 0.4 -0.6 0.6
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.4 7.1 -0.9 -0.1 -0.7 -2.7 -1.2 1.6 -0.7 2.4
Ever unenthusiastic/disinterested for a whole week 2.8 3.4 8.1 -1.4 -2.0 -1.9 -1.4 -2.3 2.8 0.6 1.5
Qualifications: None of the above 0.3 0.7 3.5 -1.9 0.4 -1.0 -0.6 -0.1 0.1 -0.8 -0.4
Financial difficulties in last 2 years 2.1 2.9 5.4 -1.1 -2.3 -2.2 -1.7 -2.0 0.8 -1.4 1.6
Mouth/teeth dental problems 0.3 0.4 1.4 0.3 0.5 0.5 0.1 1.2 -0.5 -1.0 0.0
Heart attack 0.9 1.2 2.4 -0.2 1.2 0.9 1.1 1.5 -1.3 0.4 -1.2
Allergy 0.1 0.3 0.8 0.6 -0.8 -0.8 0.3 -0.2 -0.9 -0.2 0.0
Pain all over the body in last month 1.3 1.4 2.7 1.0 1.0 1.3 0.9 1.6 -0.5 1.1 -1.5
Diabetes (self-reported) 0.3 0.4 1.8 -1.3 0.3 -0.4 -0.3 -0.2 1.1 0.1 -0.1
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 1.7 -0.9 0.1 -0.3 -0.1 -0.4 1.3 -0.0 0.3
Medication: Ramipril 0.9 1.1 1.8 0.9 0.5 0.4 1.4 1.2 -1.1 -1.3 -1.2
Medication: Simvastatin 0.5 0.8 1.9 -0.3 1.3 0.9 1.0 1.4 -0.7 -0.2 -0.8
Fluid intelligence score 0.5 1.1 2.6 -0.4 -1.3 -1.6 -0.9 -1.3 0.9 -0.1 0.7
Illnesses of siblings 0.8 1.1 3.2 -0.5 -0.3 -0.1 -1.8 -1.4 1.1 1.4 0.8
Neuroticism score 0.8 1.7 4.1 -1.1 -1.4 -1.3 -0.9 -2.0 1.5 1.0 0.7
Weight 0.2 1.1 3.2 0.6 -1.4 -1.2 1.8 -0.9 -0.1 -0.1 -0.8
Impedance of arm (right) 0.2 1.1 2.1 0.7 1.5 1.4 -0.8 0.9 -1.1 -0.8 0.7
Arm fat percentage (right) 0.2 0.9 2.7 0.6 0.4 0.2 1.6 0.3 -1.5 -1.3 -0.2
Trunk fat-free mass 0.3 1.9 6.3 0.2 -2.5 -2.1 1.0 -1.5 0.9 0.3 -0.7
Hip circumference 0.5 2.0 9.9 1.3 -1.2 -0.7 3.1 -0.8 -0.9 -0.8 -0.4
Time employed in main current job 1.6 1.8 6.0 -1.1 0.3 -0.2 -2.0 0.1 0.8 -2.5 1.7
Alcohol intake versus 10 years previously 0.9 1.3 2.9 -0.5 -1.6 -1.7 1.4 -1.1 0.3 0.6 -1.0
Father’s age at death 0.7 0.9 2.1 1.0 1.2 1.5 -0.6 0.2 -0.2 -1.2 0.8
Worrier / anxious feelings 0.7 1.4 3.5 -0.8 -1.1 -1.0 -1.1 -1.9 1.1 -0.3 1.5
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 2.1 -0.4 -1.4 -0.8 0.1 -1.3 0.5 -0.5 0.8
Falls in the last year 1.6 2.2 5.3 -2.3 -1.2 -1.7 -0.9 -1.3 1.8 1.5 0.3
Hair/balding pattern: Pattern 3 1.2 1.8 7.6 0.6 1.1 1.3 -2.8 0.7 -0.5 -1.2 1.1
Number of live births 2.3 3.3 7.6 1.7 2.8 2.5 -0.3 2.4 -1.5 1.0 -0.9
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 2.9 0.6 -0.8 -0.3 -1.7 -0.4 0.1 -1.1 0.9
Pulse rate 0.3 0.5 1.1 -1.1 0.6 0.5 -0.8 0.9 0.4 -0.8 0.5
Happiness 1.9 2.3 5.7 0.5 1.1 1.6 -2.0 0.1 -0.5 -2.1 2.4
Noisy workplace 1.9 2.4 8.6 2.2 -1.0 0.4 2.9 0.3 -0.4 0.5 -1.9
Qualifications: A levels/AS levels or equivalent 0.6 1.3 4.5 -0.6 0.1 -0.1 -2.1 0.4 0.4 -1.5 1.6
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.1 2.4 0.6 1.2 1.5 0.9 1.2 -0.5 1.0 -1.1
Mouth/teeth dental problems: Dentures 0.3 0.5 1.4 0.2 0.8 0.7 -1.2 0.5 -1.0 -0.7 -0.0
Asthma 1.5 3.0 7.5 -1.5 -1.1 -1.4 -1.2 -2.0 2.7 -0.7 2.2
Medication: Ibuprofen (e.g. Nurofen) 1.9 2.4 4.1 0.0 -2.0 -1.4 1.9 -1.8 1.2 2.0 -0.8
Medication: Cholesterol lowering 0.6 0.9 2.9 0.4 0.6 0.6 1.7 1.1 -1.1 -0.6 -1.1
Depression (self-reported) 0.9 1.1 2.3 0.3 -1.5 -1.2 1.1 -1.4 0.7 -0.6 0.7
Medication: Lansoprazole 0.1 0.2 0.5 -0.7 0.4 0.2 -0.0 0.5 0.1 -0.5 -0.1
Prospective memory result 0.7 0.9 3.1 0.3 -0.3 -0.2 1.0 0.4 -1.0 1.2 -1.8
Lung cancer (father) 0.2 0.2 0.7 -0.8 0.2 -0.5 -0.2 -0.2 0.5 0.3 -0.2
Illnesses of mother 0.9 1.2 3.1 -0.7 -1.3 -1.2 -0.7 -1.8 1.0 0.3 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.5 1.6 1.3 -1.0 -0.4 -0.8 -0.3 -0.2 -0.3 0.3
Pulse wave Arterial Stiffness index 1.3 1.6 4.9 1.3 0.5 0.7 2.2 0.9 -1.0 0.3 -1.8
Impedance of arm (left) 0.1 0.6 1.1 0.5 1.0 1.1 -0.8 0.4 -0.7 -0.8 0.7
Arm fat mass (right) 0.2 0.7 3.5 0.7 -0.3 -0.3 1.9 -0.1 -0.9 -0.6 -0.5
Trunk predicted mass 0.4 2.0 6.5 0.2 -2.5 -2.2 1.0 -1.6 1.0 0.3 -0.6
Standing height 0.1 1.1 2.8 0.7 -1.7 -1.2 -0.7 -1.1 1.3 0.5 -0.5
Length of working week for main job 2.7 3.0 6.2 -0.8 -2.5 -2.2 -0.8 -2.2 1.2 -1.8 1.4
Exposure to tobacco smoke at home 0.7 0.8 2.0 -1.1 1.1 -0.1 -0.0 0.6 -0.2 1.3 -1.4
Breastfed as a baby 0.6 0.8 3.6 0.2 0.3 0.6 -0.1 0.3 -0.2 1.9 -1.4
Tense / ‘highly strung’ 1.5 2.5 6.7 -1.1 1.5 1.0 -2.6 0.2 1.1 -1.3 2.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.1 4.8 -1.1 0.2 0.0 -1.3 -0.7 0.9 -0.2 2.2
Hair/balding pattern: Pattern 4 6.3 15.3 72.8 -5.5 -0.5 -2.5 -8.5 -1.9 2.0 1.7 1.4
Birth weight of first child 0.4 0.7 1.4 -1.1 -0.5 -1.0 -0.0 -1.0 1.0 -0.2 1.2
Peak expiratory flow (PEF) 0.2 0.4 1.2 0.8 -1.0 -0.7 0.2 -1.1 0.0 0.2 0.1
Pulse wave reflection index 0.7 0.9 2.4 1.5 0.4 0.5 1.2 0.4 -1.3 -0.3 -1.0
Ever highly irritable/argumentative for 2 days 0.3 0.4 2.1 1.4 -0.3 0.5 0.9 0.2 -0.0 0.0 -0.3
Loud music exposure frequency 0.4 0.5 1.5 -0.3 -0.2 -0.2 -1.2 -0.4 0.9 -0.2 1.1
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 2.3 -0.3 -1.5 -0.9 -0.0 -0.8 0.7 0.4 0.4
Mouth/teeth dental problems: Bleeding gums 1.0 1.2 3.2 -0.7 -0.6 -0.9 -1.8 -0.9 1.2 -0.6 1.5
Blood clot in the leg (DVT) 1.3 1.6 5.5 0.8 -0.3 0.2 1.2 0.2 -0.5 2.2 -2.4
Medication: Paracetamol 0.2 0.4 1.1 -0.2 -1.1 -0.9 0.9 -0.4 -0.5 0.0 -0.1
Headache pain in last month 0.4 0.6 2.8 -0.1 -0.3 -0.4 -1.0 -0.4 -0.6 -1.7 0.7
Medication for cholesterol, blood pressure or diabetes 1.4 2.3 5.6 -0.4 -1.7 -1.4 -0.4 -2.4 2.1 1.4 1.2
Glaucoma (self-reported) 0.7 0.8 2.1 -0.7 0.7 0.1 -1.2 0.5 -0.0 -1.5 1.2
Gout (self-reported) 0.5 0.7 2.5 -1.0 -0.6 -0.8 1.6 -0.0 0.3 0.2 -0.9
Hypothyroidism/myxoedema (self-reported) 1.2 2.4 8.0 0.9 2.8 2.4 0.3 2.0 -0.7 0.2 -0.3
Medication: Amlodipine 0.1 0.1 0.4 0.2 0.6 0.4 -0.2 0.2 -0.3 -0.2 -0.2
Medication: Ventolin 100micrograms inhaler 1.0 1.3 1.8 -0.7 -1.3 -1.3 -0.6 -1.4 1.3 -1.0 1.1
Birth weight 0.5 1.0 3.3 1.2 -0.7 -0.5 1.8 0.2 -1.3 -0.8 -0.2
Chronic bronchitis/emphysema (mother) 0.2 0.3 1.4 0.1 1.2 0.5 -0.2 0.6 -0.3 0.1 -0.0
High blood pressure (siblings) 0.7 1.0 5.7 -0.3 -0.8 -1.1 0.0 0.1 0.2 -2.4 0.3
Forced vital capacity (FVC), Best measure 0.1 0.5 2.7 0.7 -0.7 -0.4 -1.6 -0.4 0.5 -0.1 0.3
Body fat percentage 0.2 0.8 2.5 0.3 1.1 0.6 1.6 0.5 -1.1 -0.4 -0.5
Leg fat percentage (right) 0.7 2.7 5.0 0.5 2.2 1.5 2.2 1.5 -1.7 1.1 -1.8
Arm fat-free mass (right) 0.4 2.2 5.5 -0.5 -2.4 -2.3 0.7 -1.9 1.6 0.5 -0.3
Exposure to tobacco smoke outside home 0.5 0.7 3.3 -0.3 0.6 0.4 0.9 0.4 -0.4 1.8 -0.9
Comparative body size at age 10 0.9 2.4 5.9 -0.3 -2.3 -2.4 -0.1 -2.1 0.3 -1.4 1.3
Number of full brothers 0.9 1.1 2.8 1.7 0.3 0.7 1.3 0.3 -1.5 -1.0 -0.1
Worry too long after embarrassment 0.6 1.1 2.7 -0.7 -1.3 -1.2 -0.5 -1.7 0.8 0.4 1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.5 0.6 0.0 0.6 -0.2 -0.4 -0.4 -0.8 1.2
Wheeze or whistling in the chest in last year 0.3 0.5 1.2 -0.8 0.5 0.1 1.0 0.5 0.4 1.1 -0.8
Number of children fathered 0.5 0.6 2.6 -1.6 -0.3 -0.8 0.3 -0.6 0.9 0.6 0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 1.3 -1.0 -0.8 -1.1 0.1 -0.9 0.8 -0.4 0.2
Age at first live birth 1.2 2.0 7.6 -1.0 -0.5 -0.5 -1.7 -1.4 0.7 -1.5 2.8
Pulse wave peak to peak time 1.5 1.8 5.3 -1.3 -0.7 -0.9 -2.3 -1.2 1.3 -0.1 1.7
Health satisfaction 0.2 0.3 0.7 0.6 0.4 0.8 0.5 0.2 -0.8 -0.4 0.2
Shortness of breath walking on level ground 3.1 3.7 6.7 2.1 1.4 2.0 1.6 1.7 -1.8 1.8 -2.6
Qualifications: College or University degree 0.9 2.7 8.9 -1.2 -0.8 -1.1 -1.3 -1.1 2.0 -1.7 3.0
Eye problems/disorders: None of the above 1.2 1.4 4.1 -0.5 -1.8 -1.7 0.1 -2.0 0.3 -0.5 0.6
Mouth/teeth dental problems: Loose teeth 0.8 0.9 2.1 -0.7 1.4 1.0 -0.8 0.9 0.0 1.4 -0.6
Emphysema/chronic bronchitis 0.5 0.6 1.5 -1.2 1.0 -0.0 -1.1 0.4 0.4 -0.2 0.8
Medication for pain relief, constipation, heartburn 0.9 1.5 4.2 1.0 2.0 2.0 -0.7 1.5 -0.5 -0.3 -0.3
Neck or shoulder pain in last month 0.4 0.6 1.5 0.1 -0.7 -0.7 -0.1 -0.8 1.2 -0.1 1.1
Medication: Blood pressure 1.8 3.3 7.2 1.4 1.4 1.7 1.6 2.4 -2.7 -1.2 -1.7
Angina (self-reported) 1.7 2.2 5.2 0.2 2.3 1.7 -0.3 2.0 -1.3 -1.6 1.2
Migraine (self-reported) 0.1 0.1 0.2 -0.2 -0.0 -0.5 -0.0 -0.4 0.1 -0.3 -0.5
Medication: Ibuprofen 1.8 2.1 3.7 -0.5 -1.9 -1.5 0.9 -1.9 1.8 1.8 -0.4
Medication: Allopurinol 0.3 0.4 1.9 -1.4 -0.2 -1.0 0.2 0.3 0.5 -0.2 -0.5
Medication: Omeprazole 0.0 0.1 0.3 -0.2 -0.3 0.0 0.1 0.5 -0.1 0.2 -0.0
Medication: Seretide 50 evohaler 0.3 0.3 0.7 -0.3 0.9 0.2 -0.7 0.7 -0.1 -0.8 0.2
Mean time to correctly identify matches 0.5 0.9 1.7 0.5 1.0 1.3 0.7 1.2 -1.0 -0.2 -1.0
Heart disease (mother) 0.3 0.3 0.7 -0.4 0.8 0.4 -0.8 0.4 0.9 0.5 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.6 0.1 -1.2 -0.9 0.2 -1.3 0.2 0.1 0.2
Whole body fat mass 0.1 0.6 3.0 0.5 -0.1 -0.3 1.7 -0.1 -0.7 -0.5 -0.6
Leg fat mass (right) 0.2 0.9 4.2 0.5 0.2 -0.1 2.1 0.1 -1.0 0.4 -1.3
Arm predicted mass (right) 0.5 2.4 6.7 0.1 -2.6 -2.3 1.1 -1.8 1.3 0.6 -0.6
Pulse rate, automated reading 1.2 3.9 10.5 0.3 3.2 2.3 -0.6 3.1 -1.6 -1.3 -0.7
Alcohol intake frequency. 0.3 0.6 2.6 0.8 -0.2 0.1 0.7 0.3 -1.6 -0.3 -1.0
Comparative height size at age 10 0.6 3.2 6.4 -1.2 -2.1 -2.5 -1.4 -2.5 2.2 0.3 0.4
Number of full sisters 0.5 0.6 1.3 0.1 -1.1 -0.9 0.7 -0.7 -0.6 0.3 -1.0
Suffer from ‘nerves’ 0.6 1.0 1.9 0.9 0.9 1.3 -0.2 1.4 -1.3 -0.5 -0.6
Overall health rating 0.2 0.5 1.6 -0.8 0.3 0.3 1.0 -0.1 0.6 1.3 -0.5
Chest pain or discomfort 0.8 1.2 3.3 0.4 1.8 1.6 0.4 1.5 -0.9 -0.4 0.3
Had major operations 1.2 1.4 3.3 -1.6 -0.3 -0.8 -0.6 -1.3 1.8 1.6 -0.2
Age at last live birth 1.3 1.8 3.4 -1.3 -1.3 -1.2 -1.3 -1.7 0.8 -1.1 1.8
Family relationship satisfaction 0.8 1.0 3.1 0.8 -1.3 -0.4 -0.4 -1.8 0.6 0.8 1.0
Leg pain on walking 1.7 2.1 4.8 1.3 0.3 0.7 1.8 1.0 -1.1 2.0 -2.2
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.1 2.1 1.4 0.4 1.0 1.5 0.8 -0.6 1.3 -1.1
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.3 0.7 0.3 0.8 1.1 0.8 -0.4 -0.1 -1.1
Illness, injury, bereavement, stress in last 2 years 1.4 1.7 3.0 -0.8 -1.1 -1.4 -1.4 -1.7 1.2 -1.2 1.6
Medication: Aspirin 0.3 0.4 1.8 -1.4 -0.2 -0.7 -0.2 -0.3 0.6 -0.2 0.6
Supplements: Vitamin C 0.8 0.9 2.4 -0.4 -1.2 -0.9 -0.6 -1.6 0.8 -0.1 1.2
Knee pain experienced in last month 0.6 0.9 2.1 0.5 0.8 1.1 0.7 1.1 -0.4 1.1 -1.5
Hypertension (Self-reported) 0.9 2.5 4.2 1.3 1.9 1.9 1.1 1.8 -1.5 0.4 -2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 4.0 4.7 14.5 -1.9 0.3 -0.6 -2.5 -0.5 1.0 -3.4 3.8
Illnesses of father: Heart disease 0.5 0.7 1.4 -1.2 -0.8 -0.7 -0.8 -0.4 -0.0 -1.2 1.0
Illnesses of siblings: Diabetes 0.7 0.8 1.7 0.7 0.5 0.5 1.2 1.3 -0.8 0.4 -1.3
Smoking status: Previous 1.8 2.7 4.8 -1.7 -1.8 -2.2 -0.3 -2.1 1.8 1.4 -1.0
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.8 5.9 0.9 -2.4 -1.5 -0.2 -1.9 0.8 -0.5 0.7
Whole body fat-free mass 0.4 2.5 8.8 0.3 -3.0 -2.3 1.1 -1.9 0.9 -0.1 -0.4
Leg fat-free mass (right) 0.8 4.2 15.1 0.4 -3.9 -2.9 1.1 -2.6 0.9 -0.9 0.4
Arm fat percentage (left) 0.2 0.9 3.2 0.7 0.0 -0.1 1.8 -0.1 -1.4 -1.2 -0.2
Average weekly red wine intake 0.9 1.3 6.0 2.5 0.1 1.2 0.8 0.8 -1.1 -0.2 -0.6
Handedness (chirality/laterality): Left-handed 0.4 0.5 2.3 0.1 0.6 0.5 0.1 0.5 -0.4 -0.7 1.5
Mood swings 1.3 2.3 5.1 -1.1 -1.9 -1.7 0.4 -2.3 2.0 0.6 1.0
Loneliness, isolation 1.1 1.5 3.9 -2.0 -1.2 -1.4 -0.4 -1.1 1.6 1.1 0.1
Long-standing illness, disability or infirmity 0.6 0.9 3.1 -0.4 0.7 0.1 1.0 0.6 0.5 1.8 -1.2
Ever had bowel cancer screening 3.2 3.8 6.7 2.6 1.8 2.5 1.4 2.2 -2.5 -0.6 -0.7
Diabetes diagnosed by doctor 0.3 0.5 1.7 -0.3 0.6 0.3 1.0 0.7 0.2 0.7 -1.3
Ever had stillbirth, spontaneous miscarriage or termination 1.8 1.9 4.2 1.5 0.6 1.1 1.2 1.4 -1.7 0.8 -2.1
Friendships satisfaction 0.7 0.8 2.7 0.7 -0.6 0.1 0.3 -1.0 -0.4 -1.4 1.7
Qualifications: nursing, teaching 0.7 1.0 3.0 -0.1 0.8 0.5 -1.7 0.3 0.3 -1.0 1.7
Commuting to job workplace: Walk 0.5 0.5 2.6 0.2 -0.2 -0.0 -0.6 -0.5 0.0 -1.1 1.6
Eye problems/disorders: Cataract 1.1 1.2 3.6 0.4 1.9 1.6 -1.1 1.4 0.0 0.4 -0.3
Mouth/teeth dental problems: Mouth ulcers 1.7 2.7 9.7 0.7 -1.6 -0.8 3.1 -1.0 1.0 2.1 -1.1
Medication for cholesterol 1.5 2.3 4.7 -1.0 -1.5 -1.7 -1.4 -1.8 0.3 -1.7 2.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.4 1.1 1.0 0.2 0.6 0.5 0.9 -0.7 -0.7 -0.0
Back pain experienced in last month 0.4 0.6 1.3 0.3 -1.0 -0.7 0.9 -1.1 0.0 1.0 -0.2
Mineral and other dietary supplements 0.3 0.4 1.8 1.4 0.3 0.2 0.5 0.4 -0.3 -0.4 -0.6
Breast cancer (self-reported) 0.4 0.5 1.4 -0.2 1.0 0.5 -0.7 0.8 0.0 -1.2 0.6
Asthma (self-reported) 1.4 2.8 7.2 -1.5 -1.2 -1.5 -1.0 -2.0 2.7 -0.4 1.9
Osteoporosis (self-reported) 0.8 1.0 2.2 1.5 1.0 1.4 0.4 0.7 -0.6 -1.1 0.8
Osteoarthritis (self-reported) 0.1 0.1 0.7 -0.0 0.0 -0.2 0.3 0.4 -0.4 0.1 -0.9
Medication: Aspirin 0.7 0.9 3.2 -1.8 -0.6 -1.3 -0.3 -0.7 0.7 -0.5 0.7
Medication: Gliclazide 0.7 0.8 2.1 0.6 -0.1 0.1 1.5 0.5 -0.2 1.3 -1.4
Illnesses of father: None of the above (group 1) 2.0 2.5 5.6 1.5 2.4 2.1 -0.3 2.0 -1.7 -0.5 -0.0
Smoking status: Current 0.9 1.5 3.0 0.8 1.1 1.6 0.5 1.1 -0.7 1.7 -1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 3.3 1.1 0.4 0.8 -1.8 0.5 -0.4 0.2 0.1
Whole body water mass 0.5 2.6 8.9 0.2 -3.0 -2.4 1.1 -2.0 1.0 -0.1 -0.3
Leg predicted mass (right) 0.7 3.9 14.3 0.6 -3.8 -2.8 1.2 -2.5 0.7 -0.9 0.3
Arm fat mass (left) 0.2 0.8 2.9 0.5 -0.9 -0.9 1.7 -0.7 -0.6 -0.8 -0.3
Number of self-reported non-cancer illnesses 0.4 0.7 2.0 -0.2 0.9 0.9 0.1 0.7 0.3 1.4 -1.2
Average weekly champagne plus white wine intake 0.7 1.0 2.6 -0.6 1.6 0.9 -1.0 0.8 -0.2 -1.3 1.0
Miserableness 2.3 4.0 9.8 -1.4 -3.1 -3.0 0.7 -2.9 1.3 -0.0 0.6
Guilty feelings 0.8 1.3 7.3 0.4 0.6 0.9 0.7 -0.2 0.7 2.7 -0.5
Wears glasses or contact lenses 0.8 0.9 1.7 1.1 1.3 1.3 -0.4 1.3 -0.5 -0.7 -0.2
Ever taken oral contraceptive pill 0.3 0.3 1.0 0.6 0.2 0.8 -0.3 1.0 -0.6 0.1 0.3
Hearing aid user 0.5 0.5 1.8 -0.5 1.3 0.7 0.1 1.2 -0.0 0.2 -0.7
Mother’s age at death 1.3 1.7 2.5 1.3 1.0 1.5 1.5 1.1 -1.2 0.9 -1.6
Financial situation satisfaction 0.4 0.5 1.5 0.8 0.2 0.5 -0.5 0.6 -0.8 -1.2 0.6
Tinnitus: Yes, now most or all of the time 2.1 2.4 6.0 -1.2 -2.1 -2.4 -0.6 -1.9 1.1 -1.2 0.8
Commuting to job workplace: Public transport 1.3 1.6 2.9 1.7 0.8 1.3 -0.8 1.2 -1.5 -1.7 0.7
Eye problems/disorders: Glaucoma 0.4 0.5 1.8 0.2 1.3 0.9 -0.3 1.0 0.0 -0.4 0.4
Medication: Blood pressure 2.1 3.9 9.6 2.0 0.9 1.5 2.5 1.6 -1.3 1.9 -3.1
Pain type(s) experienced in last month: Hip pain 0.6 0.8 3.3 0.9 -0.2 0.6 1.8 0.5 -0.0 0.9 -0.8
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.1 -1.1 -0.1 0.1 -0.8 -0.2 0.1 -0.4 1.0
High cholesterol (Self-reported) 2.1 3.8 8.0 1.5 2.3 2.5 1.3 2.8 -2.2 -1.2 -0.7
Medication: Bendroflumethiazide 0.3 0.4 1.5 -0.2 -0.6 -0.6 0.6 -0.4 0.5 0.3 -1.2
Medication: Paracetamol 0.1 0.2 0.4 -0.2 -0.6 -0.7 0.4 -0.2 -0.2 0.1 -0.5
Medication: Lisinopril 0.1 0.2 0.6 0.1 -0.2 -0.0 -0.8 -0.7 0.3 -0.2 0.5
Medication: Atorvastatin 0.6 0.8 1.4 0.7 0.9 1.1 1.2 1.1 -0.9 -0.1 0.0
Illnesses of father: High blood pressure 2.8 3.5 6.4 -1.8 -2.3 -2.5 -1.2 -2.5 1.8 -0.6 1.5
Alcohol drinker status: Never 0.9 1.0 2.2 1.0 0.9 1.0 1.0 1.5 -1.3 -0.8 0.3
Ever smoked 0.7 1.2 4.7 -1.1 0.1 0.2 -0.0 -0.2 1.2 2.2 -1.5
Basal metabolic rate 0.4 2.4 7.9 0.2 -2.8 -2.3 1.2 -1.9 0.8 -0.1 -0.3
Leg fat percentage (left) 0.5 1.8 3.9 0.6 2.0 1.2 1.6 1.3 -1.5 0.7 -1.3
Arm fat-free mass (left) 0.4 1.8 4.6 -0.4 -2.1 -2.1 1.0 -1.5 1.2 0.6 -0.5
Number of operations (self-reported) 0.5 0.8 2.0 -1.2 0.3 -0.2 -1.2 -0.2 1.4 1.1 -0.3
Average weekly beer plus cider intake 1.7 2.5 7.5 -2.7 -1.5 -2.1 -0.3 -1.8 0.9 0.3 1.2
Irritability 1.0 1.7 3.8 -0.7 -1.6 -1.4 0.1 -1.9 1.9 0.6 0.6
Risk taking 0.3 0.4 1.6 0.8 0.1 0.7 0.1 0.1 0.3 1.3 -0.7
Ever had prostate specific antigen (PSA) test 0.7 0.8 1.8 0.6 0.9 0.8 -0.5 1.2 -0.9 -1.4 -0.1
Fractured/broken bones in last 5 years 0.7 0.9 1.3 -1.0 -1.1 -1.1 0.1 -1.1 0.7 0.9 -0.8
Age started oral contraceptive pill 1.8 2.2 6.0 0.9 2.5 2.0 1.0 1.8 -0.9 1.0 -0.8
Diastolic blood pressure, automated reading 0.3 1.1 3.4 -0.1 1.8 1.0 -0.8 1.4 -1.0 -0.3 -0.6
Ever depressed for a whole week 1.8 2.2 4.3 -1.4 -0.8 -1.1 -2.0 -1.3 2.1 0.1 2.0
Unable to work because of sickness or disability 0.3 0.4 1.6 -0.3 -1.3 -0.6 -0.3 -0.4 0.7 0.4 -0.2
Commuting to job workplace: Cycle 0.5 0.6 2.2 0.5 -1.5 -1.0 -0.6 -0.2 -0.5 -0.9 0.4
Myopia 0.4 0.5 1.8 -0.4 0.6 0.3 -0.8 -0.7 0.7 0.4 1.4
Vascular/heart problems diagnosed by doctor 0.9 2.5 4.9 -0.9 -2.2 -1.9 -0.8 -2.2 1.6 0.0 1.5
Cholesterol lowering medication 0.7 1.0 3.3 -1.1 1.8 1.1 -0.8 1.4 0.2 0.3 0.3
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 1.1 0.5 -0.5 0.1 0.5 0.6 -1.0 -0.7 -0.1
Pain experienced in last month 0.5 0.8 2.0 -1.4 0.9 0.1 -1.3 0.4 1.0 0.4 1.0
Supplements: Calcium 0.7 0.8 1.9 0.3 0.9 1.4 0.4 0.7 -0.9 1.2 -0.6
Basal cell carcinoma (self-reported) 1.7 2.0 4.2 1.3 2.0 2.0 0.1 1.7 -0.8 -1.5 -0.1
Heart attack/myocardial infarction (self-reported) 0.7 0.9 1.8 -0.5 1.2 0.8 0.8 1.4 -1.0 0.5 -1.1
Deep venous thrombosis (DVT) (self-reported) 1.6 2.1 7.7 0.9 -0.2 0.4 1.4 0.4 -0.9 2.2 -2.8
Heart disease (siblings) 0.4 0.5 1.5 -0.0 0.7 0.0 0.3 0.9 -1.2 -0.5 -0.9
Alcohol drinker status: Previous 0.7 0.8 2.4 0.7 0.5 0.6 1.5 0.3 -0.4 0.5 -1.6
Pack years of smoking 0.1 0.2 0.4 -0.5 0.6 0.5 -0.0 0.6 0.2 0.3 -0.0
Impedance of whole body 0.3 1.6 5.3 -0.2 2.3 1.6 -1.8 1.0 -0.2 0.3 0.5
Leg fat mass (left) 0.2 0.6 3.0 0.4 -0.0 -0.4 1.7 -0.1 -0.8 0.1 -1.0
Arm predicted mass (left) 0.4 2.1 5.4 -0.3 -2.3 -2.2 1.1 -1.7 1.1 0.7 -0.6