[Hub]/) : Traits : Age when periods started (menarche) : ← →

chr1:43,042,125-45,109,101

Best TWAS P=2.88e-11 · Best GWAS P=2.54e-11 conditioned to 0.0951

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ELOVL1 0.04 0.01 enet 11 0.01 6.3e-03 -3.9 5.2 2.0e-07 -0.34 0.66 0.10 FALSE
2 GTEx Heart Left Ventricle TIE1 0.22 0.04 lasso 11 0.04 5.3e-03 -3.8 5.6 2.5e-08 -0.62 0.31 0.64 FALSE
3 GTEx Heart Left Ventricle MED8 0.08 0.01 lasso 3 0.01 1.2e-01 -6.7 6.7 2.9e-11 -0.89 0.03 0.87 TRUE
4 GTEx Lung HYI 0.18 0.04 enet 22 0.06 1.8e-05 -4.6 5.5 3.7e-08 -0.48 0.95 0.02 FALSE
5 GTEx Muscle Skeletal ST3GAL3 0.10 0.01 enet 27 0.01 1.6e-02 -6.7 6.3 3.3e-10 -0.73 0.01 0.99 FALSE
6 GTEx Muscle Skeletal RP11-7O11.3 0.05 0.02 lasso 3 0.02 7.2e-03 4.5 -5.2 2.4e-07 0.55 0.13 0.20 FALSE
7 GTEx Nerve Tibial MED8 0.13 0.07 enet 11 0.16 3.6e-11 -4.5 -6.1 1.1e-09 0.52 0.93 0.06 FALSE
8 GTEx Pancreas HYI 0.22 0.16 enet 9 0.20 9.7e-09 4.6 5.9 3.7e-09 -0.33 0.96 0.01 FALSE
9 GTEx Stomach HYI 0.16 0.06 lasso 6 0.07 4.1e-04 4.6 5.6 1.9e-08 -0.30 0.37 0.16 FALSE
10 ROSMAP Brain Pre-frontal Cortex TMEM125 0.02 0.01 lasso 4 0.01 7.4e-03 -3.7 5.2 1.8e-07 -0.71 0.06 0.84 FALSE
11 The Cancer Genome Atlas Rectum Adenocarcinoma HYI 0.23 0.08 blup 34 0.14 3.1e-04 4.6 5.3 1.4e-07 -0.35 0.01 0.56 FALSE