TWAS hub - RN7SL417P

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0660	0.0290	6.8e-04	0.057	NA	0.035	NA	0.045	1.9e-05	NA	7.2e-04	NA	1.3e-04
2	GTEx	Artery Aorta	0.2030	0.0680	2.7e-06	0.037	NA	0.080	NA	0.044	3.8e-03	NA	3.3e-05	NA	1.8e-03
3	GTEx	Artery Tibial	0.1026	0.0357	4.8e-05	0.031	NA	0.020	NA	0.019	1.8e-03	NA	1.0e-02	NA	1.1e-02
4	GTEx	Breast Mammary Tissue	0.1180	0.0500	5.2e-03	-0.002	NA	-0.004	NA	-0.005	4.0e-01	NA	5.6e-01	NA	7.5e-01
5	GTEx	Breast Mammary Tissue (Male)	0.1998	0.1011	2.6e-02	0.122	NA	0.007	NA	0.097	9.5e-04	NA	2.1e-01	NA	3.1e-03
6	GTEx	Breast Mammary Tissue (Female)	0.1393	0.0710	1.4e-02	0.008	NA	0.009	NA	0.011	1.8e-01	NA	1.7e-01	NA	1.5e-01
7	GTEx	Colon Sigmoid	0.1670	0.0770	1.7e-03	0.059	NA	0.085	NA	0.118	3.9e-03	NA	6.1e-04	NA	6.1e-05
8	GTEx	Colon Transverse	0.1550	0.0540	2.6e-05	0.084	NA	0.112	NA	-0.003	8.4e-05	NA	5.6e-06	NA	5.1e-01
9	GTEx	Esophagus Muscularis	0.1010	0.0480	8.2e-04	0.019	NA	0.036	NA	-0.002	2.4e-02	NA	3.1e-03	NA	4.2e-01
10	GTEx	Muscle Skeletal	0.0375	0.0187	7.9e-03	-0.003	NA	-0.003	NA	0.002	8.4e-01	NA	9.1e-01	NA	2.0e-01
11	GTEx	Ovary	0.2100	0.0830	6.2e-03	0.007	NA	0.073	NA	0.053	2.1e-01	NA	7.4e-03	NA	2.0e-02
12	GTEx	Skin Not Sun Exposed Suprapubic	0.3220	0.0880	3.5e-04	0.019	NA	0.071	NA	0.029	2.9e-02	NA	1.0e-04	NA	1.0e-02
13	GTEx	Testis	0.0890	0.0410	1.9e-03	0.077	NA	0.055	NA	0.075	2.7e-04	NA	1.9e-03	NA	3.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Bipolar Disorder or Schizophrenia	11.2	27.4	56.3	-7.5	-6.1	-5.2	-4.5	-5.2	-3.0	-7.0	-4.5	-6.0	1.3	-4.1	-2.7	-7.0
Comparative height size at age 10	9.3	51.4	127.7	9.4	6.2	6.0	5.6	11.3	3.0	10.5	5.9	7.8	-3.8	3.2	5.7	8.6
Impedance of whole body	9.3	47.5	156.2	8.2	6.3	4.7	4.4	12.5	0.4	10.2	4.0	7.5	-3.9	1.1	8.4	7.0
Impedance of leg (right)	8.6	41.8	144.0	7.7	5.2	3.8	3.7	12.0	-0.1	9.8	3.9	6.8	-3.8	0.7	8.1	6.8
Bipolar Disorder (2011)	8.5	8.3	14.8	-3.5	-3.2	-3.3	-2.9	-1.7	-2.8	-3.5	-3.9	-3.5	2.6	-0.8	-0.9	-2.7
Impedance of arm (left)	8.4	38.9	123.2	7.5	6.2	4.7	4.6	11.1	0.8	9.0	3.7	6.8	-3.5	1.4	7.0	6.3
Impedance of leg (left)	8.3	40.2	134.6	7.6	5.2	4.0	3.7	11.6	0.3	9.8	4.0	7.0	-3.5	1.0	7.6	6.4
Schizophrenia (2018)	8.0	16.7	34.8	-5.9	-4.5	-4.1	-3.4	-4.6	-2.3	-5.7	-3.9	-4.6	1.4	-2.2	-0.8	-5.5
Impedance of arm (right)	7.5	34.8	123.2	6.9	5.7	4.0	4.2	11.1	0.2	8.5	3.1	6.1	-3.0	0.9	7.0	6.1
Schizophrenia (2014)	7.4	16.3	34.2	-5.8	-4.6	-4.0	-3.3	-4.3	-2.1	-5.8	-3.8	-4.8	0.5	-2.8	-0.8	-5.1
Forced expiratory volume in 1-second (FEV1), predicted	7.4	15.3	35.8	5.6	4.1	3.0	2.6	5.4	0.9	6.0	2.0	4.3	-0.2	3.0	1.9	5.9
Bipolar Disorder (2018)	7.1	11.2	21.7	-4.7	-4.1	-3.2	-3.0	-2.5	-2.0	-4.0	-2.4	-3.4	0.3	-3.7	-3.3	-4.4
Standing height	6.9	68.4	171.0	12.0	7.7	5.9	5.0	12.4	1.4	13.1	5.6	9.2	-2.3	4.8	6.7	10.6
Height	6.6	126.6	357.2	15.3	9.0	7.7	7.4	18.9	2.3	17.5	6.9	12.4	-2.6	7.0	10.5	13.4
Forced expiratory volume in 1-second (FEV1)	4.8	16.2	36.4	5.1	2.9	3.0	3.2	5.8	2.6	6.0	3.9	4.8	-1.4	3.8	3.5	3.7
Forced expiratory volume in 1-second (FEV1), Best measure	4.7	15.0	37.8	5.0	2.8	2.7	3.5	6.1	2.4	5.9	3.3	4.3	-0.9	3.3	3.0	3.9
Tinnitus: Yes, now most or all of the time	4.3	5.0	10.0	-1.7	-1.7	-3.0	-2.8	-1.6	-3.1	-1.7	-3.2	-2.6	2.4	-1.3	-1.4	-1.1
Medication: Atenolol	4.2	5.2	10.0	-1.7	-2.5	-3.2	-2.5	-0.9	-2.7	-2.0	-2.7	-2.8	2.7	-1.6	-2.4	-0.4
Forced vital capacity (FVC), Best measure	4.1	14.9	28.6	4.6	3.1	3.6	3.8	5.4	3.2	5.3	3.7	4.6	-1.4	3.6	2.8	3.2
Number of full sisters	4.0	4.8	10.4	-2.9	-2.5	-1.8	-1.8	-2.8	-1.0	-3.2	-1.9	-2.6	-0.8	-1.0	1.5	-2.8
Trunk fat percentage	3.9	15.6	47.7	5.1	3.6	1.5	0.8	6.9	-1.0	6.6	2.3	4.3	-3.4	-1.1	3.2	4.7
Forced vital capacity (FVC)	3.8	14.5	27.0	4.5	3.0	3.6	3.5	4.6	3.2	5.2	4.1	4.8	-1.7	3.8	3.1	2.9
Had menopause	3.4	4.3	10.5	-2.2	-2.0	-2.5	-2.1	-0.5	-2.5	-1.8	-2.3	-2.3	1.5	-1.2	0.8	-3.2
Falls in the last year	3.4	4.6	7.5	2.0	1.9	2.1	2.4	2.7	2.3	2.0	2.1	2.2	-0.3	2.1	2.7	1.8
Illnesses of siblings: Diabetes	3.4	4.2	11.9	1.3	1.2	2.4	2.5	1.0	2.7	0.7	3.1	1.4	-3.4	0.1	2.4	1.0
Commuting to job workplace: Walk	3.4	3.7	6.4	-2.4	-1.7	-2.5	-1.4	-0.9	-1.8	-2.3	-2.4	-2.4	2.2	-0.4	-1.5	-1.9
Mean Putamen Volume	3.3	3.7	7.7	-2.5	-2.6	-2.4	-1.6	-1.8	-1.1	-2.1	-1.5	-2.0	1.7	-0.8	-0.5	-2.8
Trunk fat mass	3.2	13.8	40.7	5.2	3.4	1.4	0.6	6.0	-0.9	6.4	2.4	4.0	-3.0	-0.7	2.5	4.8
Qualifications: nursing, teaching	3.2	4.9	10.9	2.9	2.8	2.2	1.9	2.2	0.9	3.3	2.3	2.7	-1.2	-0.1	1.8	2.4
Illnesses of mother	2.9	3.6	7.5	2.5	2.7	2.4	1.9	1.4	1.2	2.1	1.5	2.2	-0.9	1.0	-0.5	2.6
Supplements: Glucosamine	2.8	3.6	5.7	2.0	2.3	2.2	2.2	1.6	2.0	1.9	2.4	2.0	-1.0	1.9	1.2	1.7
Waist Hip Ratio (WHR)	2.7	12.3	28.7	4.9	3.3	3.2	2.4	3.3	1.7	5.4	1.7	4.3	0.6	4.6	2.7	4.0
Commuting to job workplace: Car/motor vehicle	2.6	2.9	6.7	1.5	1.1	2.2	2.0	-0.1	2.5	0.9	2.2	1.4	-2.6	0.0	1.4	1.6
Alzheimer’s Disease (including proxy)	2.5	3.6	5.9	-2.0	-1.7	-2.1	-2.3	-2.4	-2.0	-2.0	-1.9	-2.4	2.0	-0.5	0.6	-1.4
Pulse rate, automated reading	2.5	8.1	13.3	-3.6	-3.2	-3.1	-3.1	-2.5	-2.9	-3.5	-2.8	-3.3	0.8	-2.1	-1.8	-2.9
Type 2 Diabetes (T2D) (2018)	2.4	4.5	8.2	2.7	2.1	2.2	1.3	1.9	0.9	2.5	2.5	2.6	-1.8	0.5	2.9	2.1
Sitting height	2.3	16.3	44.2	6.3	4.3	2.8	1.1	4.7	-0.1	6.7	2.9	4.5	-2.1	0.1	2.6	6.3
Chronic bronchitis/emphysema (father)	2.3	2.7	6.2	-2.2	-1.6	-1.4	-1.5	-1.5	-1.1	-2.5	-1.4	-2.2	0.2	-2.0	-0.7	-1.7
Body fat percentage	2.3	9.0	28.9	3.7	2.5	0.6	0.1	5.4	-1.1	5.1	1.7	3.1	-3.1	-1.5	2.2	3.4
Lung FEV1/FVC ratio	2.2	11.1	38.4	4.8	1.1	-0.7	-0.6	5.6	-2.8	6.2	-0.2	2.8	1.8	1.5	3.5	4.1
Hypothyroidism/myxoedema (self-reported)	2.1	4.0	11.9	2.6	2.3	1.5	0.7	2.8	-0.7	2.3	0.3	1.8	-0.8	-0.1	3.5	2.8
Heel T-Score	2.0	15.8	28.2	-5.2	-4.4	-3.6	-5.3	-3.8	-3.7	-5.2	-3.2	-4.2	-1.8	-3.6	1.1	-4.3
Heel bone mineral density (BMD) T-score, automated (left)	2.0	4.5	9.0	-2.2	-2.0	-2.9	-2.6	-1.2	-3.0	-1.8	-2.4	-2.6	1.9	-1.8	-0.3	-1.1
Medication: Ventolin 100micrograms inhaler	2.0	2.6	6.8	-2.2	-1.9	-1.4	-1.6	-2.6	-0.5	-2.2	-1.0	-1.6	0.0	-0.6	-1.7	-1.7
Medication: Allopurinol	2.0	2.6	7.7	2.1	1.5	0.7	1.3	1.9	0.3	2.0	0.7	1.4	2.2	2.8	0.3	1.5
Eye problems/disorders: Glaucoma	2.0	2.4	6.2	-1.2	-1.1	-1.7	-2.3	-0.5	-2.5	-1.5	-1.9	-1.6	0.7	-2.1	-0.0	-0.7
Worry too long after embarrassment	1.9	3.2	7.3	2.3	1.9	1.5	0.4	0.9	0.3	2.5	2.3	2.1	-2.4	-0.6	-0.1	2.7
Hearing difficulty/problems: Yes	1.8	2.7	8.6	-1.7	-1.6	-1.5	-2.2	-2.7	-1.3	-0.9	-1.0	-1.1	-0.3	-1.3	-0.3	-2.9
Whole body fat mass	1.8	7.4	22.4	3.7	2.3	0.6	-0.2	4.4	-1.1	4.7	1.6	2.8	-2.8	-1.2	1.6	3.6
Peak expiratory flow (PEF)	1.7	3.9	6.3	1.9	1.3	1.9	2.1	2.1	2.5	2.2	2.4	2.3	-1.6	2.0	1.6	1.5
Average weekly champagne plus white wine intake	1.7	2.3	7.5	1.7	2.3	0.9	1.2	2.7	0.1	2.1	0.6	1.5	0.8	-0.4	0.4	1.9
Allergy or Eczema	1.6	4.2	8.6	-2.7	-2.2	-2.1	-0.5	-1.8	-1.4	-2.8	-2.3	-2.9	1.8	-0.7	-0.4	-2.5
Hypothyroidism (self reported)	1.6	3.7	9.5	2.8	2.2	1.0	0.4	3.0	-1.3	2.2	-0.4	1.5	-0.2	-1.2	2.4	3.1
Age at first live birth	1.6	2.8	6.4	2.3	2.1	1.7	1.7	1.6	0.5	2.2	1.2	1.6	-1.5	-0.6	1.0	2.5
Back pain experienced in last month	1.6	2.3	5.7	1.9	2.0	1.8	0.2	0.1	1.3	1.9	1.9	2.4	-1.1	1.0	1.4	0.9
Ever used hormone-replacement therapy (HRT)	1.5	2.0	4.3	-1.4	-1.5	-0.9	-1.4	-1.9	-1.2	-2.1	-0.9	-1.6	-0.4	-1.8	0.4	-1.4
Gout (self-reported)	1.5	2.0	4.3	2.1	1.5	0.7	1.2	1.9	0.2	2.0	0.9	1.3	1.3	1.4	0.5	1.9
Shortness of breath walking on level ground	1.5	1.7	5.0	2.0	1.6	1.4	1.5	1.1	0.9	2.2	0.7	1.5	0.3	1.3	0.0	0.7
Pain all over the body in last month	1.4	1.5	4.7	0.4	0.4	1.4	1.9	0.2	2.2	0.6	1.9	1.0	-1.8	0.5	0.7	-0.2
Number of full brothers	1.4	1.8	4.7	-2.0	-1.4	-1.2	-0.1	-1.6	0.2	-2.2	-0.2	-1.5	0.5	-0.8	-1.1	-1.9
Wheeze or whistling in the chest in last year	1.4	2.5	5.2	-1.9	-1.5	-1.2	-1.4	-2.3	-0.5	-2.2	-0.6	-1.8	-0.9	-0.9	-1.6	-2.1
Eye problems/disorders: None of the above	1.4	1.6	5.2	1.0	0.2	0.9	2.3	0.9	2.1	0.7	1.6	0.7	0.1	1.9	-0.5	0.7
Supplements: Fish oil (including cod liver oil)	1.4	1.8	9.7	1.2	1.7	1.2	1.1	1.3	0.5	1.0	0.1	1.1	-0.1	1.1	3.1	1.2
Irritability	1.4	2.3	7.8	2.4	2.3	1.4	0.4	1.5	-0.5	1.8	0.5	1.6	-0.5	-0.0	0.8	2.8
Age at First Birth	1.3	1.8	4.6	1.0	0.9	2.1	1.8	-0.3	2.2	0.4	1.8	1.3	-2.1	-0.0	-0.3	0.6
Diabetes (father)	1.3	1.6	3.8	1.5	1.3	1.1	1.6	0.5	1.3	1.4	2.0	1.2	-1.4	-0.9	0.4	1.3
Hair/balding pattern: Pattern 2	1.3	1.6	4.1	0.3	0.9	1.7	2.0	0.9	1.8	0.2	1.9	1.1	-1.7	-0.4	-1.0	0.4
Medication: Simvastatin	1.3	1.9	5.3	-0.7	-1.2	-1.6	-2.3	-1.4	-2.1	-0.3	-2.1	-0.7	1.0	-0.4	0.9	-0.7
Guilty feelings	1.3	2.0	4.7	1.3	1.4	1.7	0.2	0.2	1.4	1.7	2.2	2.0	-2.0	0.6	-0.5	0.9
Rheumatoid Arthritis	1.2	1.6	8.0	0.6	0.8	0.9	-0.5	0.4	-0.3	0.8	0.7	0.9	-2.8	-2.5	1.5	0.7
Number of incorrect matches in round	1.2	2.0	5.9	-1.7	-1.2	-0.6	-1.7	-1.8	-0.2	-2.4	-0.6	-1.4	-1.1	-0.5	1.2	-2.2
Hearing difficulty/problems with background noise	1.2	2.0	6.1	-1.6	-0.9	-1.1	-2.5	-2.1	-1.6	-0.7	-1.4	-0.5	-0.4	-0.7	-0.4	-2.0
Hair/balding pattern: Pattern 3	1.2	1.8	5.9	-1.8	-1.5	-0.8	-0.7	-1.9	-0.5	-2.4	-1.2	-1.9	0.7	0.2	0.5	-1.3
Medication: Lansoprazole	1.2	1.4	4.6	0.8	0.8	1.5	1.5	-0.1	1.6	0.8	1.3	1.0	-2.2	-1.2	-0.1	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	5.6	-1.2	-1.1	-0.4	-2.1	-2.4	-0.5	-1.5	-1.0	-0.7	-0.1	0.3	1.4	-2.2
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	6.7	1.7	1.8	0.3	0.5	1.1	-0.9	1.2	-0.4	0.7	2.1	1.5	-0.0	2.6
Glaucoma (self-reported)	1.2	1.4	4.5	-0.5	-0.6	-1.3	-1.8	0.1	-2.1	-0.7	-1.8	-1.1	0.8	-1.3	-0.6	-0.2
Medication: Amlodipine	1.2	1.7	4.0	-1.0	-1.6	-2.0	-1.2	-0.9	-1.3	-0.4	-1.4	-1.3	1.8	-0.4	-1.7	-0.6
Number of children fathered	1.2	1.4	5.6	-1.8	-1.1	-0.2	-1.1	-1.4	-0.1	-1.5	-0.5	-0.7	-0.6	0.8	0.3	-2.4
Alcohol intake frequency.	1.2	2.8	7.4	-1.7	-2.0	-1.6	-2.4	-2.7	-1.4	-1.2	-1.5	-1.3	0.9	-0.0	-0.4	-2.2
Blood Eosinophil Count	1.1	8.7	32.0	-4.1	-3.5	-2.0	-3.5	-3.3	-1.4	-3.3	-1.4	-2.0	-0.7	-2.1	-0.1	-5.7
Angina	1.1	1.4	5.7	1.3	0.9	1.1	1.4	1.3	1.1	1.0	0.6	0.9	0.6	1.2	2.4	0.7
Hand grip strength (right)	1.1	2.9	8.9	0.9	0.6	2.0	2.0	0.4	2.7	1.4	2.1	1.9	-0.8	3.0	1.0	-0.9
Fed-up feelings	1.1	2.0	5.6	2.2	2.0	1.1	-0.0	1.0	-0.1	2.4	0.6	2.0	0.2	0.8	-0.0	2.1
Age when periods started (menarche)	1.1	2.7	9.7	-2.1	-1.3	-0.5	-1.4	-3.1	-0.4	-1.7	-0.4	-0.6	-1.5	-1.4	0.1	-3.0
High blood pressure (mother)	1.1	1.5	5.9	-1.4	-1.5	-1.2	-0.6	-1.4	-0.1	-1.1	-0.5	-1.3	-0.6	-2.4	-0.6	-1.2
Mineral and other dietary supplements	1.1	1.5	3.7	-1.3	-1.6	-1.1	-0.9	-1.3	-0.3	-1.3	-0.4	-1.2	-0.2	-1.7	-1.9	-1.4
Asthma (self-reported)	1.1	2.2	8.5	-2.0	-1.1	-0.4	-0.3	-2.9	0.6	-2.1	-0.3	-1.4	-0.9	-0.6	-2.2	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	4.7	1.7	0.9	0.6	0.9	2.2	0.2	1.7	0.7	1.0	0.5	0.7	-0.1	1.4
Frequency of depressed mood in last 2 weeks	1.0	1.4	3.2	1.8	1.1	-0.0	-0.8	0.9	-1.4	1.8	-0.8	1.0	1.7	0.3	0.6	1.6
Relative age of first facial hair	1.0	2.0	5.2	2.3	1.9	0.9	1.0	1.8	0.4	1.9	1.0	1.3	-0.1	-0.0	-0.4	2.3
Medication: Metformin	1.0	1.4	2.9	1.4	0.8	1.0	1.2	1.6	0.8	1.3	1.4	1.3	-0.1	1.1	1.7	0.7
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	6.1	-1.5	-1.0	-1.9	-2.2	-0.9	-2.5	-1.2	-1.6	-1.7	0.9	-1.3	0.8	-0.9
Qualifications: A levels/AS levels or equivalent	1.0	2.1	7.5	1.8	1.9	1.1	1.7	1.8	0.3	1.7	1.0	1.3	-0.4	0.1	-0.5	2.7
Mouth/teeth dental problems: Dentures	1.0	1.7	4.6	-2.0	-1.8	-0.8	0.1	-0.7	0.1	-2.1	-1.0	-1.3	0.4	-1.0	-0.9	-2.0
Asthma	1.0	2.1	9.0	-1.8	-1.0	-0.3	-0.3	-3.0	0.6	-2.0	-0.2	-1.2	-1.2	-0.5	-1.8	-1.4
Leg fat percentage (right)	1.0	3.8	11.2	1.7	0.7	-0.6	-1.0	3.4	-1.7	3.0	0.7	1.4	-2.9	-2.4	1.5	1.7
Age started oral contraceptive pill	1.0	1.2	3.8	-1.4	-0.7	-1.0	-1.0	0.5	-1.4	-0.8	-1.4	-0.8	0.4	-2.0	-0.1	-1.3
Heart disease (siblings)	1.0	1.2	4.4	-0.2	-0.6	0.6	1.6	0.1	2.1	-0.9	1.3	-0.4	-1.1	2.0	0.5	-0.5
Depressed Affect (Nagel 2018)	0.9	1.9	4.1	1.4	1.7	1.6	0.1	0.4	0.6	1.8	1.9	2.0	-1.3	-0.7	1.8	0.6
Respiratory disease	0.9	1.9	8.4	-1.8	-0.8	-0.0	-0.3	-2.9	0.6	-2.0	-0.3	-1.1	-1.6	-0.8	-1.5	-1.3
Medication: Co-codamol	0.9	1.1	3.3	1.2	1.5	0.9	-0.4	0.3	0.3	1.1	1.2	1.3	-1.3	0.0	0.3	1.8
Severe depression (siblings)	0.9	1.1	2.6	-0.5	-0.7	-1.0	-1.4	-1.0	-1.2	-0.5	-1.2	-0.6	0.2	-1.6	-1.4	-0.9
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	2.8	-0.7	-1.2	-1.1	-1.6	-0.7	-1.6	-0.7	-0.4	-0.9	0.5	-1.7	0.3	-0.5
Serious illness, injury or assault to yourself	0.9	1.1	5.1	0.9	0.0	-0.6	0.8	1.9	-0.5	1.1	-0.9	0.2	2.3	0.7	-1.2	0.6
Body mass index (BMI)	0.9	3.7	8.0	-2.0	-1.8	-2.2	-2.3	-2.8	-0.9	-2.0	-1.0	-1.9	-0.4	-2.0	-2.5	-1.6
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.0	-0.9	-1.3	-1.2	-0.6	-0.5	-0.8	-1.0	-1.2	-1.3	1.4	-0.4	-1.4	-1.1
Fluid intelligence score	0.9	1.8	4.3	1.6	1.6	0.5	-0.3	0.9	-1.0	1.7	0.1	1.0	-1.1	-2.1	1.6	2.0
Weight	0.9	4.4	15.0	3.4	1.7	0.5	-0.0	2.9	-0.4	3.9	1.5	2.2	-1.4	0.1	0.5	3.3
Chronic bronchitis/emphysema (mother)	0.9	1.1	4.0	-1.0	-0.1	-0.2	-1.4	-0.9	-0.5	-0.9	-1.0	-0.2	1.1	1.2	2.0	-1.4
Angina (self-reported)	0.9	1.2	6.1	1.0	0.7	1.0	1.1	1.0	1.1	0.8	0.5	0.8	0.5	1.3	2.5	0.3
Breast cancer (self-reported)	0.9	1.1	5.8	-0.0	-0.3	-1.0	0.4	0.5	-1.2	-0.4	-1.8	-1.0	2.4	-0.3	1.1	0.4
Illnesses of father: High blood pressure	0.9	1.1	3.7	1.1	1.5	0.7	0.7	0.8	0.2	1.1	0.7	0.7	-1.1	-1.9	0.1	1.5
Commuting to job workplace: Cycle	0.9	1.1	2.6	1.2	1.3	1.2	1.2	1.3	0.6	1.0	0.5	1.2	0.3	0.6	1.6	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	5.2	0.3	1.1	1.0	-0.0	-1.2	0.7	1.1	0.6	1.4	0.4	2.3	0.8	-1.2
Alzheimer’s Disease (in father)	0.8	0.9	2.0	-1.2	-1.3	-1.1	-0.1	-0.8	0.1	-1.2	-0.4	-1.4	0.9	0.2	-0.4	-1.3
Body Mass Index (BMI) (2010)	0.8	1.1	4.5	-0.8	-0.8	-0.9	-1.1	-1.6	-0.5	-1.1	-0.1	-1.0	0.3	-2.1	-1.1	-0.3
Blood Red Count	0.8	7.9	18.9	3.6	3.2	2.5	0.6	4.3	-0.3	3.9	1.4	3.6	-0.8	2.1	2.4	3.7
Lung FVC	0.8	3.9	16.0	0.3	-0.1	1.8	2.6	0.8	4.0	0.7	3.0	1.7	-0.4	2.7	0.9	-1.8
Ever had hysterectomy (womb removed)	0.8	0.9	5.1	0.2	-0.3	-0.6	-0.9	0.5	-1.4	0.1	-0.5	-0.5	0.3	-2.3	1.7	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.7	1.5	0.9	0.1	-0.5	1.2	-1.6	1.6	-0.5	0.6	1.2	-0.0	0.6	1.3
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	3.8	0.9	1.3	1.0	1.2	0.4	0.9	0.4	0.9	0.7	-0.3	0.2	1.9	0.6
Multivitamins +/- minerals	0.8	1.0	2.5	-1.1	-0.6	-0.6	-1.3	-1.6	-1.1	-1.1	-1.3	-0.8	0.8	0.2	0.4	-1.3
Medication: Levothyroxine sodium	0.8	1.3	4.2	1.5	0.9	0.8	0.9	2.0	-0.1	1.2	-0.0	0.8	-0.1	-0.0	1.8	1.7
Alcohol usually taken with meals	0.8	1.4	7.1	-0.7	-0.4	-1.3	-0.6	-0.1	-1.7	-0.4	-1.5	-0.9	2.7	-1.1	-0.3	-0.5
Mouth/teeth dental problems	0.8	1.2	2.5	1.4	1.5	1.1	-0.1	0.3	-0.1	1.6	0.6	1.1	-1.1	1.2	1.2	1.2
Allergy	0.8	1.8	6.4	2.1	0.9	0.4	-0.2	2.5	-0.4	2.1	0.8	1.3	0.2	-0.4	0.3	2.0
Illnesses of siblings	0.8	1.1	4.5	0.6	0.9	-0.0	-1.0	0.1	-1.2	1.5	-1.1	1.1	2.1	0.8	-1.0	0.3
Hip circumference	0.8	3.3	9.5	2.1	0.6	-0.5	-0.9	2.6	-1.0	3.1	1.1	1.2	-2.6	-1.9	0.4	2.5
Number of live births	0.8	1.1	4.3	-1.7	-0.9	-0.3	-0.8	-1.6	-0.4	-1.2	-0.4	-0.6	-0.6	-0.5	0.5	-2.1
Prospective memory result	0.8	0.9	4.1	-0.8	-1.1	-0.8	-0.7	-0.9	-0.7	-0.8	-1.1	-0.9	2.0	0.1	-0.8	-0.6
Pulse wave Arterial Stiffness index	0.8	0.9	5.3	1.4	0.8	0.4	0.2	1.5	0.0	0.8	0.6	0.4	-0.2	0.3	-0.3	2.3
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.4	1.3	0.9	-0.1	-1.0	-0.0	-1.5	1.1	-1.1	0.5	1.0	-0.6	0.3	1.5
Blood clot in the leg (DVT)	0.8	1.0	3.0	0.2	1.1	0.8	-0.4	-1.3	0.3	1.0	0.2	1.3	0.4	1.7	1.3	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	3.6	-0.6	-0.3	0.6	1.7	0.0	1.9	-0.9	1.4	-0.2	-1.0	-0.6	-0.2	-0.5
Leg fat mass (right)	0.8	3.0	9.1	2.2	0.9	-0.5	-1.1	2.6	-1.4	3.0	0.7	1.4	-2.1	-1.6	0.9	2.2
Family relationship satisfaction	0.8	1.0	4.0	-1.0	-1.2	-0.7	-0.5	-1.1	-0.3	-0.8	-0.9	-0.7	0.1	-1.5	-0.2	-2.0
Leg pain on walking	0.8	1.0	5.2	-0.4	-0.9	-0.6	-0.6	-0.2	-0.1	0.0	-0.8	-0.0	1.6	2.3	1.0	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	4.0	0.7	0.5	0.6	1.4	1.6	1.0	0.4	0.8	0.6	-0.0	2.0	0.8	0.1
Medication: Aspirin	0.8	1.0	4.6	0.3	-0.2	0.3	1.0	1.2	0.7	0.4	0.2	0.6	1.2	2.1	1.8	-0.3
Knee pain experienced in last month	0.8	1.2	2.8	-1.0	-0.6	-1.4	-1.4	-0.8	-1.6	-0.6	-1.7	-0.7	1.1	-0.5	1.2	-1.2
Eye problems/disorders: Cataract	0.8	0.9	2.9	0.6	1.1	0.7	-0.6	0.4	-0.5	0.8	0.0	0.9	-1.7	-0.9	1.6	1.1
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	2.7	-1.4	-1.2	-1.4	-0.8	-0.8	-0.5	-1.6	-0.7	-1.6	0.6	-1.0	-0.3	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	5.4	-1.2	-0.7	-0.7	0.5	-0.1	0.2	-0.3	0.1	-0.5	2.3	0.8	-0.1	-1.9
Leg fat percentage (left)	0.8	2.9	7.7	1.4	0.6	-0.7	-1.1	2.8	-1.4	2.8	0.7	1.3	-2.5	-2.2	1.1	1.3
Ever depressed for a whole week	0.8	1.0	2.7	-1.2	-1.0	-0.8	-1.4	-1.1	-0.6	-1.1	-1.4	-0.9	-0.0	0.2	-0.0	-1.6
Alcohol drinker status: Previous	0.8	0.9	4.8	0.7	0.5	0.5	-0.7	-0.2	-0.6	1.2	0.2	0.8	-1.5	-0.6	2.2	-0.4
Verbal and Numeric Reasoning (VNR)	0.7	1.6	5.5	1.3	1.5	0.2	0.3	1.5	-0.7	2.3	0.4	1.1	0.4	-1.7	-0.9	1.7
HbA1C	0.7	0.8	2.9	1.1	1.5	0.5	-0.7	0.9	-0.5	1.7	0.2	0.8	0.2	0.5	0.7	1.0
Triglycerides	0.7	1.2	3.3	-0.5	-0.3	-1.6	-1.3	1.0	-1.8	0.1	-1.3	-0.9	1.1	-1.4	-0.4	0.5
Chronotype (morning person)	0.7	1.6	3.0	1.3	1.5	1.2	0.3	1.6	-0.4	1.1	0.7	1.4	-1.3	-1.5	1.5	1.7
Hand grip strength (left)	0.7	1.8	7.4	-0.8	-0.9	0.6	1.2	-0.2	2.5	-0.2	1.0	0.2	-0.2	2.7	-0.1	-2.2
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	3.6	0.8	0.4	0.5	0.1	0.3	0.4	1.0	0.9	1.1	1.0	1.9	0.8	0.4
Diabetes (mother)	0.7	0.9	2.6	-1.0	-1.2	-0.1	0.4	-0.7	1.6	-0.8	0.7	-0.2	-0.7	1.1	-1.0	-1.2
Qualifications: CSEs or equivalent	0.7	0.9	2.3	-1.2	-1.5	-0.9	-0.7	-0.8	0.1	-1.5	-0.7	-1.1	0.6	1.0	0.5	-1.0
Heart attack	0.7	0.9	2.7	1.5	1.1	0.7	0.1	0.4	-0.3	1.6	0.7	1.3	0.7	0.6	0.3	1.3
Breastfed as a baby	0.7	0.9	2.4	-1.2	-0.7	-1.0	-1.1	-1.0	-0.9	-0.8	-0.4	-0.7	0.2	-1.0	1.0	-1.5
Tense / ‘highly strung’	0.7	1.1	2.7	-1.3	-0.9	-0.6	-0.7	-1.4	-0.2	-1.6	-0.8	-1.3	0.2	0.3	-1.2	-1.6
Emphysema/chronic bronchitis	0.7	0.8	2.7	-1.2	-0.4	-0.0	-1.0	-1.7	-0.2	-0.9	-0.7	-0.3	-1.2	-0.1	-0.4	-1.5
Migraine (self-reported)	0.7	0.8	3.9	-0.2	-1.1	0.1	-0.6	-2.0	0.7	0.2	0.6	0.2	-0.9	0.3	-1.5	-1.1
Heart disease (mother)	0.7	0.9	2.8	-0.6	-1.0	-0.8	-1.7	0.3	-1.2	-0.3	-1.1	-0.4	0.5	0.7	1.5	-0.8
Long-standing illness, disability or infirmity	0.7	1.1	2.3	-0.8	-0.7	-1.2	-1.5	-1.2	-1.4	-0.2	-1.5	-0.7	1.3	0.5	1.0	-0.9
Financial situation satisfaction	0.7	0.9	1.9	1.2	0.7	1.1	1.1	0.3	1.1	0.8	1.1	0.8	0.7	1.4	0.4	0.6
Diastolic blood pressure, automated reading	0.7	2.1	8.6	1.5	1.3	-0.4	0.2	2.2	-1.5	0.7	-0.6	-0.1	0.1	-2.5	-0.6	2.9
Myopia	0.7	1.0	3.3	-0.5	-0.3	-1.3	-1.0	0.1	-1.5	0.1	-1.1	-0.4	0.9	-1.8	0.2	-1.1
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.7	1.5	1.2	0.7	0.0	0.5	-0.3	1.6	0.7	1.4	0.7	0.4	0.3	1.4
Leg fat mass (left)	0.7	2.6	8.5	2.0	0.7	-0.5	-1.1	2.3	-1.3	2.9	0.7	1.3	-1.8	-1.4	0.6	2.0
Depression (Nagel 2018)	0.6	0.9	2.9	1.0	0.8	-0.2	-0.4	0.8	-1.5	1.5	-0.4	0.6	1.7	0.2	1.3	0.4
Neuroticism (Nagel 2018)	0.6	1.4	3.9	1.1	1.2	1.4	0.2	0.4	0.7	1.4	2.0	1.7	-1.5	-0.4	0.9	0.8
Alzheimer’s Disease (in mother)	0.6	0.7	1.4	-0.7	-0.3	-0.8	-0.8	-0.6	-1.2	-0.8	-1.2	-1.2	1.1	0.1	1.1	-0.0
Crohns Disease (2017)	0.6	1.4	6.2	-0.4	-0.1	1.2	0.8	-0.9	1.6	-0.8	1.2	0.6	-2.5	-0.3	1.5	-1.4
Irritable Bowel Disease (IBD)	0.6	1.4	4.7	0.1	1.0	1.5	0.5	-0.3	1.0	0.3	1.4	1.4	-1.9	-0.6	2.2	-1.0
LDL Cholesterol	0.6	0.9	7.2	-0.4	-0.6	-0.3	-0.3	-0.4	-0.5	-0.6	0.3	-0.7	-1.2	-2.7	-0.9	-0.4
Neuroticism (2016)	0.6	0.9	2.2	0.0	-1.2	-1.3	-0.8	-0.2	-1.4	-0.6	-0.8	-0.9	0.7	-1.0	-1.5	0.6
Sensitivity / hurt feelings	0.6	1.1	5.2	-1.2	-0.8	-0.0	-0.6	-0.9	0.1	-0.9	0.1	-0.4	-2.3	-1.6	0.4	-1.4
Stomach or abdominal pain in last month	0.6	0.7	5.2	-0.5	-0.8	-0.7	-0.2	0.0	-0.4	-0.4	-0.4	-0.7	1.3	0.7	-2.3	0.0
Waist circumference	0.6	2.0	7.9	2.1	0.8	-0.0	-0.5	1.6	-0.3	2.8	0.9	1.5	-1.7	-0.2	0.2	2.1
Happiness	0.6	0.7	3.9	0.9	-0.0	-0.5	-0.8	0.3	-1.1	1.1	-0.0	0.3	2.0	0.2	-0.4	0.7
Exposure to tobacco smoke outside home	0.6	0.8	2.1	0.7	0.5	1.2	0.8	1.1	0.4	-0.1	0.8	0.4	-1.1	-0.5	1.1	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.8	-0.4	0.3	0.8	-0.1	-1.7	0.6	-0.8	-0.0	0.1	-0.7	-0.0	1.3	-1.5
Medication: Ibuprofen	0.6	0.7	3.5	-0.0	0.0	0.1	-1.1	-1.9	0.7	0.2	1.2	0.7	-1.2	0.4	0.1	-0.2
Medication: Seretide 50 evohaler	0.6	0.7	2.3	-1.0	-0.5	0.2	-0.5	-1.3	0.2	-1.1	0.2	-0.5	-1.5	-1.0	0.5	-0.9
Age at last live birth	0.6	0.8	3.2	-0.6	-0.8	-1.2	0.1	0.7	-1.1	-0.2	-0.9	-0.8	0.4	-1.8	-0.8	-0.6
Average weekly red wine intake	0.6	0.9	3.7	1.2	1.3	-0.0	-0.5	-0.6	-1.2	1.2	-0.3	0.5	-0.4	-1.9	-0.5	0.8
Diabetes diagnosed by doctor	0.6	1.0	3.2	1.3	0.9	0.7	0.1	1.0	-0.4	1.3	0.8	1.2	-0.1	0.5	1.8	1.2
Medication: Aspirin	0.6	0.8	2.8	0.4	0.0	0.3	0.9	1.3	0.4	0.3	-0.0	0.6	1.3	1.7	1.5	0.0
Hearing aid user	0.6	0.7	2.8	-0.0	-0.1	-1.2	-1.7	-0.6	-1.2	0.4	-0.4	-0.2	1.1	-0.9	0.3	-0.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.7	0.9	1.1	1.1	0.4	0.6	0.6	1.0	0.9	1.2	-0.4	0.2	1.3	0.4
Unable to work because of sickness or disability	0.6	0.8	4.5	-0.5	0.1	0.5	0.8	-0.3	1.1	0.7	0.5	0.9	0.8	0.8	-0.5	-2.1
Cholesterol lowering medication	0.6	0.9	1.8	-0.9	-0.8	-0.9	-1.2	-0.7	-0.9	-1.2	-1.3	-0.9	0.5	-0.2	1.3	-0.8
Pack years of smoking	0.6	0.9	2.5	1.4	1.0	0.6	-1.4	0.3	-0.8	1.1	-0.0	0.9	-1.1	-0.3	0.7	1.6
Ulcerative Colitis (UC)	0.5	0.9	2.0	0.5	1.4	1.0	-0.2	0.3	0.2	1.0	1.3	1.4	-1.1	-0.8	1.3	-0.1
Coronary Artery Disease (CAD)	0.5	0.6	2.4	-0.1	0.4	1.0	1.1	0.6	1.5	0.2	0.8	0.7	-1.1	0.2	-0.0	-0.8
Systolic blood pressure, automated reading	0.5	1.4	3.3	-0.9	-0.9	-1.7	-1.0	-0.6	-1.5	-1.0	-1.8	-1.5	1.1	-1.2	-0.5	-0.5
Pack years adult smoking proportion	0.5	0.7	2.9	1.2	0.7	0.3	-1.4	0.3	-0.9	0.9	-0.1	0.6	-0.8	-0.1	0.3	1.7
Had other major operations	0.5	0.6	2.3	0.4	0.5	0.9	1.5	0.3	1.4	0.8	0.7	0.7	0.2	0.7	-0.2	-0.1
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	3.3	0.3	0.4	-0.1	1.1	0.9	0.3	0.5	0.0	0.4	0.1	-1.0	-1.8	1.1
Time employed in main current job	0.5	0.5	1.9	-1.4	-0.6	-0.2	-0.4	0.3	0.1	-1.2	-0.4	-0.7	-0.9	0.1	0.9	-0.8
Pulse rate	0.5	0.8	4.1	-0.4	-0.3	-0.5	-2.0	-0.0	-1.7	-0.5	-1.0	-0.6	-0.9	-1.0	-0.1	0.3
Noisy workplace	0.5	0.7	1.5	-1.1	-0.9	-0.7	-0.8	-0.8	-0.8	-1.2	-0.8	-0.9	-0.2	0.0	-0.1	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.8	0.4	0.2	0.4	-0.6	-1.3	1.0	0.6	1.4	0.9	-1.0	0.4	0.3	0.4
Depression (self-reported)	0.5	0.6	1.9	-0.1	-0.5	-0.6	-1.2	-0.3	-1.0	-0.1	-1.4	-0.7	0.2	-0.7	1.2	-0.6
Pulse wave reflection index	0.5	0.6	3.4	-0.2	-0.3	-0.8	-0.0	-0.3	-0.1	-0.5	-0.3	-0.8	0.5	-1.3	-1.9	0.8
Loud music exposure frequency	0.5	0.6	2.9	-0.2	-0.4	0.6	1.7	-0.5	1.3	-0.6	0.6	-0.2	-0.5	-0.7	-0.5	-0.3
Birth weight	0.5	1.1	5.8	-0.3	-0.3	-0.5	-1.4	-2.4	-1.4	-0.6	-1.5	-0.8	0.5	0.0	0.6	-0.6
High blood pressure (siblings)	0.5	0.7	3.0	-0.4	-0.9	-0.4	0.6	0.1	0.2	-1.2	0.2	-1.2	-1.7	-1.4	0.3	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.4	-0.8	0.2	-0.1	-0.7	-1.0	-0.3	-0.6	-0.3	-0.1	-0.6	-0.8	0.9	-1.6
Health satisfaction	0.5	0.7	2.7	-0.3	-0.9	-0.9	-0.8	-1.6	-0.6	0.2	-0.3	-0.2	1.0	-0.7	-1.0	-1.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.3	0.1	0.7	0.6	1.5	1.1	1.4	0.2	0.5	0.4	-0.1	0.8	0.6	0.1
Mood swings	0.5	0.9	5.3	-0.3	-0.1	-0.3	-2.3	-1.5	-1.3	0.1	-0.4	0.3	-0.2	-0.8	0.9	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.2	-0.8	-0.3	0.4	1.1	0.4	1.1	-1.1	0.3	-0.5	-1.0	0.1	-0.2	-0.9
Osteoarthritis (self-reported)	0.5	0.7	2.2	0.5	0.9	0.8	1.5	-0.1	1.5	0.7	0.8	0.9	0.2	0.2	-0.5	-0.3
Medication: Gliclazide	0.5	0.5	1.9	0.1	0.3	0.8	-0.0	-0.8	0.6	-0.0	1.3	0.6	-1.4	0.3	0.8	0.0
Intelligence (Savage-Jansen 2018)	0.4	1.1	3.8	1.5	1.2	0.1	0.0	1.4	-1.1	1.9	0.2	0.7	0.8	-0.3	0.4	1.7
Major Depression (MDD)	0.4	0.5	2.3	-0.5	-0.9	-0.3	-0.8	-0.3	-0.3	0.0	-0.6	-0.2	0.9	0.4	-0.7	-1.5
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.6	0.6	0.5	0.0	-0.3	-0.1	-0.9	1.0	0.3	0.7	-0.6	-1.3	-0.5	0.6
Blood Platelet Count	0.4	5.1	28.8	-3.3	-2.4	-1.0	0.4	-2.2	0.5	-2.4	-0.9	-1.5	2.3	0.9	0.5	-5.4
Neuroticism	0.4	1.1	2.7	1.2	1.7	1.1	-0.2	0.4	0.3	1.3	1.4	1.4	-1.0	0.3	0.1	1.0
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	2.1	0.4	0.0	0.6	1.3	0.5	1.4	0.7	0.8	0.7	-0.5	0.8	0.6	-0.2
Vitamin and mineral supplements	0.4	0.6	1.0	1.0	0.0	0.3	0.8	0.9	0.9	0.7	0.9	0.4	-0.9	-0.6	-0.8	1.0
Average weekly fortified wine intake	0.4	0.5	2.1	0.2	1.2	0.1	-0.0	0.3	-0.0	-0.0	0.7	0.1	-0.5	-0.9	1.5	1.0
Nervous feelings	0.4	0.7	2.1	-0.9	-0.3	-0.6	-1.4	-1.2	-1.0	-0.8	-0.6	-0.7	0.7	0.1	-0.6	-0.8
Diabetes (self-reported)	0.4	0.6	1.9	0.9	0.7	0.7	-0.0	0.4	-0.2	0.9	1.1	1.1	-0.4	0.5	1.4	0.6
Arm fat percentage (right)	0.4	1.5	4.8	0.7	0.6	-0.7	-0.8	1.8	-1.1	1.5	0.2	0.5	-2.1	-2.2	0.2	1.1
Alcohol intake versus 10 years previously	0.4	0.6	1.4	1.0	0.5	1.0	0.4	-0.0	0.6	0.6	1.2	1.1	-0.4	0.9	-0.7	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.2	-0.0	-0.2	-1.1	-1.4	-0.3	-1.5	0.1	-0.8	-0.6	0.3	-0.7	0.1	1.0
Medication: Cholesterol lowering	0.4	0.7	1.5	0.0	-0.5	-0.9	-1.0	-0.6	-1.2	1.0	-1.0	0.3	1.2	0.7	0.4	-0.5
Lung cancer (father)	0.4	0.4	2.5	-0.6	-0.6	-0.6	-0.5	-0.2	-0.6	-0.7	-0.5	-0.5	0.1	-1.6	0.2	-0.3
Exposure to tobacco smoke at home	0.4	0.5	1.6	0.1	0.2	-0.2	-1.2	0.1	-1.3	-0.2	-0.9	-0.2	0.7	-0.5	0.9	0.7
Birth weight of first child	0.4	0.8	3.1	0.2	-0.3	-1.0	-0.9	0.2	-0.9	0.8	-0.2	0.3	1.8	0.8	-1.5	-0.7
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.3	0.4	0.5	0.2	1.2	0.7	0.7	0.3	0.4	0.4	1.5	0.8	-0.2	0.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.9	-0.5	0.5	1.0	0.8	-0.4	1.3	-0.9	1.0	-0.1	-1.4	-0.4	0.1	-0.4
Comparative body size at age 10	0.4	1.1	4.6	-1.1	-0.0	-0.1	0.2	-2.2	1.1	-1.4	0.8	-0.4	0.7	-0.8	-1.2	-1.6
Qualifications: College or University degree	0.4	1.1	2.3	1.1	1.3	0.8	1.5	0.7	0.8	1.5	1.4	1.1	-0.4	-0.2	-1.1	1.0
Neck or shoulder pain in last month	0.4	0.6	2.7	-1.2	-0.8	-0.6	-1.3	-0.9	-0.4	-0.5	0.0	-0.1	-0.1	0.1	-0.1	-1.6
Medication: Blood pressure	0.4	0.7	1.5	0.9	-0.1	-0.8	-0.7	1.1	-1.2	1.2	-0.4	0.3	1.2	0.1	-0.1	1.1
Medication: Omeprazole	0.4	0.4	1.4	0.8	0.0	-0.3	-0.2	1.2	-0.9	1.2	-0.4	0.3	0.6	0.3	-0.7	0.4
Mean time to correctly identify matches	0.4	0.7	2.9	-1.5	-0.5	-0.1	-0.7	-0.8	0.1	-0.9	-0.1	-0.4	-1.1	-0.3	0.2	-1.7
Chest pain or discomfort	0.4	0.6	1.5	-0.7	-0.6	-0.8	-1.1	-0.5	-0.8	-0.4	-1.2	-0.6	0.7	0.8	0.3	-0.7
Illnesses of father: Heart disease	0.4	0.6	2.9	0.0	-0.1	0.6	0.5	-0.5	1.2	0.1	0.6	0.6	-0.3	1.7	0.7	-0.8
Smoking status: Previous	0.4	0.7	2.9	0.6	0.9	0.7	0.8	-0.0	0.2	0.7	0.8	0.7	-1.2	-1.7	0.4	0.2
Arm fat percentage (left)	0.4	1.7	4.6	1.1	0.9	-0.5	-0.7	2.0	-1.0	1.8	0.4	0.8	-2.1	-1.8	0.0	1.4
Loneliness, isolation	0.4	0.5	3.7	0.2	0.1	-0.3	0.0	0.0	-0.6	0.9	-0.3	0.4	1.9	-0.1	-1.2	-0.6
Ever had bowel cancer screening	0.4	0.5	2.0	-0.3	0.5	0.6	1.0	1.4	0.8	-0.1	1.2	0.2	-0.8	0.0	-0.3	-0.4
Friendships satisfaction	0.4	0.5	1.1	1.0	0.6	0.0	0.2	0.5	-0.6	1.0	0.2	0.2	1.1	-1.0	-0.8	0.7
Arm fat mass (left)	0.4	1.6	3.9	1.4	0.7	-0.5	-1.0	1.4	-1.0	1.9	0.4	0.8	-2.0	-1.6	0.1	1.7
Ever smoked	0.4	0.8	1.8	1.1	1.0	1.0	1.3	1.3	0.5	0.9	0.5	0.6	-0.0	-0.2	1.0	0.7
Average weekly beer plus cider intake	0.4	0.5	2.2	0.6	0.2	0.8	1.5	0.4	0.3	-0.0	0.2	0.2	-1.1	-1.0	0.7	0.7
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.6	-1.5	-0.5	0.6	0.2	-1.4	1.4	-1.2	0.6	-0.1	-1.6	0.3	0.0	-1.9
Basal cell carcinoma (self-reported)	0.4	0.5	2.2	-0.1	0.0	0.4	0.6	0.6	1.2	0.3	0.3	0.6	-1.1	1.5	0.6	-0.4
Breast Cancer	0.3	0.6	2.4	1.2	0.3	0.3	-0.9	0.3	-0.1	0.9	0.2	0.5	-1.6	0.5	-0.4	1.3
Ovarian Cancer	0.3	0.4	1.5	-0.4	-1.2	-0.5	0.3	-0.1	0.3	-1.2	0.1	-1.0	-0.3	-0.5	-0.7	0.2
Fasting Glucose	0.3	0.4	1.7	0.6	0.6	0.1	0.3	0.1	0.2	0.4	-0.2	-0.1	0.7	1.2	-1.3	0.7
HDL Cholesterol	0.3	0.5	2.0	-0.7	-0.4	0.3	1.0	-1.0	1.1	-0.8	0.1	-0.1	0.2	-0.1	-0.1	-1.4
Lupus	0.3	0.5	1.4	0.1	-0.2	-0.0	-0.1	0.5	-0.1	0.7	1.2	0.3	1.2	0.6	-0.9	-1.2
Smoking Status	0.3	0.7	3.4	1.1	0.7	0.3	0.7	1.8	-0.5	0.5	-0.2	0.3	0.6	-1.2	1.0	0.7
Cardiovascular Disease	0.3	1.2	5.2	1.9	0.6	-0.3	0.2	1.2	-0.8	1.5	-0.2	0.4	0.7	-0.9	-0.2	2.3
Medication for hormone replacement therapy	0.3	0.4	1.1	-0.0	-0.9	-0.6	-0.3	-0.6	-0.6	0.2	0.1	-0.3	1.0	0.0	0.8	-1.0
Townsend deprivation index at recruitment	0.3	0.4	1.3	-0.6	-0.5	-0.6	-0.5	-0.6	-0.4	-0.8	-0.7	-0.9	0.0	0.3	-1.1	0.0
Current tobacco smoking	0.3	0.4	1.3	-0.6	-1.1	-0.7	-0.9	0.3	-0.2	-0.8	-0.4	-0.7	0.5	0.8	-0.0	-0.8
Relative age voice broke	0.3	0.5	1.2	0.6	-0.1	-0.9	-0.6	0.3	-1.1	0.8	-0.7	-0.3	0.8	-1.0	-0.7	0.8
High blood pressure	0.3	0.8	2.2	0.9	-0.1	-1.0	-0.5	0.9	-1.5	0.6	-0.7	-0.4	0.8	-1.0	-0.6	1.5
Hayfever, allergic rhinitis or eczema	0.3	0.8	2.2	-1.3	-0.6	-0.3	0.8	-1.0	0.2	-1.5	-0.4	-1.1	0.5	0.2	0.8	-1.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.4	0.6	0.1	0.0	1.0	1.2	0.4	0.4	0.7	0.2	0.8	-0.5	-0.4	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	2.4	0.3	0.4	0.3	-0.6	-0.6	-0.5	0.4	-0.4	0.5	0.9	1.6	0.5	-0.5
Qualifications: None of the above	0.3	0.7	3.7	-0.6	-1.1	0.2	-0.1	0.3	0.9	-1.1	0.5	-0.4	-1.9	-0.4	0.4	-0.8
Medication: Ramipril	0.3	0.3	1.6	0.3	0.2	-0.2	-0.5	0.8	-0.4	1.0	-0.1	0.5	0.3	-0.2	-1.2	0.0
Neuroticism score	0.3	0.7	1.8	1.2	1.3	0.9	-0.6	-0.5	-0.2	1.4	0.7	1.3	-0.5	0.2	-0.4	0.6
Father’s age at death	0.3	0.4	2.1	-0.7	-0.4	-0.4	-0.1	-0.2	0.0	-0.3	-0.2	-0.3	1.4	0.4	1.0	-0.7
Worrier / anxious feelings	0.3	0.7	1.9	0.6	0.3	0.2	-1.2	-1.4	-0.3	1.1	0.7	1.0	0.0	-0.6	-1.3	-0.2
Arm fat mass (right)	0.3	1.3	3.2	1.1	0.5	-0.7	-1.1	1.3	-1.1	1.7	0.3	0.6	-1.8	-1.7	-0.1	1.4
Length of working week for main job	0.3	0.3	1.3	-0.3	-0.2	0.3	0.2	-0.9	0.2	-0.8	-0.2	-0.3	0.6	1.1	0.2	-0.7
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.6	-0.4	-0.0	-0.3	-0.6	0.3	-0.7	0.2	-0.6	0.1	1.3	0.5	0.9	-0.7
Suffer from ‘nerves’	0.3	0.4	1.2	1.1	0.6	0.3	-0.2	0.5	0.0	0.9	0.8	0.6	0.7	0.9	-0.3	0.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.0	-1.0	0.1	-0.2	-0.0	-0.9	-0.5	-0.9	-0.1	-0.5	-0.6	-0.6	0.7	-0.8
Supplements: Vitamin C	0.3	0.3	1.9	-0.1	0.3	-0.1	0.3	0.1	0.2	0.6	0.3	0.5	1.4	0.2	-1.2	-0.0
Hypertension (Self-reported)	0.3	0.8	2.4	0.5	-0.4	-1.1	-0.7	0.6	-1.4	0.3	-0.7	-0.5	0.6	-1.6	-0.8	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	3.3	0.5	-0.3	-0.5	0.5	1.8	0.1	1.3	-0.0	0.6	1.3	0.7	-0.3	-0.0
Miserableness	0.3	0.5	2.2	0.4	0.7	0.7	-0.8	-0.9	-0.1	0.3	0.2	1.0	-0.5	0.5	1.5	-0.3
Wears glasses or contact lenses	0.3	0.3	1.5	-0.0	0.6	-0.0	-1.2	0.1	-0.9	0.3	-0.4	0.3	-0.3	-0.6	0.7	0.0
Commuting to job workplace: Public transport	0.3	0.3	2.0	-0.6	-0.3	-0.5	-0.4	-0.5	-0.3	-0.1	-0.3	-0.0	0.6	-0.6	-1.4	-0.7
Medication: Blood pressure	0.3	0.6	4.6	0.1	-0.0	-0.4	-0.4	0.2	-0.9	-0.1	-0.6	-0.5	-0.5	-2.2	-0.5	1.2
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.0	0.7	0.3	-0.4	0.4	0.9	-0.3	0.6	-0.3	0.1	1.0	0.4	1.0	0.7
Medication: Paracetamol	0.3	0.5	2.2	0.4	0.5	0.7	-0.6	-0.6	0.4	0.7	0.3	1.5	-0.9	0.7	-0.1	0.1
Medication: Atorvastatin	0.3	0.4	2.4	-0.5	-0.2	-0.0	0.0	-1.5	0.1	-0.3	-0.3	-0.1	0.2	0.7	-0.2	-1.2
Alcohol drinker status: Never	0.3	0.3	1.9	-0.6	-0.4	-0.2	0.3	-0.3	0.2	0.2	0.2	0.2	1.4	0.5	-0.9	-0.8
Basal metabolic rate	0.3	1.7	6.3	2.4	0.9	0.2	-0.6	0.2	-0.1	2.1	0.9	1.0	-0.3	0.9	-1.0	2.5
Number of operations (self-reported)	0.3	0.5	2.0	0.7	0.7	0.6	0.0	0.5	-0.2	0.9	0.3	0.6	-0.2	-0.8	1.4	0.6
Risk taking	0.3	0.4	1.3	-0.6	-0.6	0.0	-0.0	-0.6	0.1	-0.6	-0.7	-0.3	0.3	0.7	1.0	-1.1
Fractured/broken bones in last 5 years	0.3	0.4	1.8	0.9	0.7	0.2	0.3	0.9	-0.2	1.3	0.1	0.9	0.3	-0.5	0.6	0.0
Supplements: Calcium	0.3	0.4	2.2	-0.4	-0.6	-0.0	0.3	0.4	0.5	-0.3	0.0	0.0	-0.6	1.5	0.8	-0.7
Schizophrenia vs Biploar Disorder	0.2	0.3	1.0	-0.1	0.3	0.2	-0.6	-1.0	-0.2	-0.5	-0.0	-0.3	-0.9	0.7	0.3	0.2
Prostate Cancer	0.2	0.3	0.7	0.9	0.8	0.8	0.0	-0.7	0.4	0.4	0.6	0.5	-0.6	-0.3	-0.1	0.8
Crohns Disease (2012)	0.2	0.3	1.8	-0.5	-0.2	0.2	0.2	-0.6	0.2	-0.7	0.5	-0.3	-1.4	-0.7	-0.4	-0.6
Primary Biliary Cirrhosis	0.2	0.2	1.1	-0.2	0.3	0.3	-0.5	-0.5	-0.6	-0.3	-0.5	0.0	-0.6	-1.0	0.2	0.4
Ulcerative Colitis	0.2	0.3	0.8	0.3	0.8	0.7	0.2	0.7	0.1	0.6	0.7	0.7	-0.1	-0.4	0.9	0.4
Blood White Count	0.2	1.2	6.2	-1.0	-1.5	-1.4	-1.1	-0.3	-1.1	-0.2	-1.1	-0.4	0.5	-0.4	0.4	-2.5
BMI	0.2	1.0	4.7	0.2	0.1	-1.0	-1.4	-1.4	-0.4	0.1	0.3	-0.3	-0.6	-1.5	-2.2	0.5
Average weekly spirits intake	0.2	0.3	1.4	-0.7	-0.2	-0.3	-0.4	0.0	0.2	-0.5	0.3	-0.5	-0.8	-1.2	-0.2	-0.1
Supplements: Zinc	0.2	0.3	1.3	0.1	0.2	-0.3	-0.4	-0.5	-0.6	0.3	-0.1	-0.2	-0.4	-1.2	-0.8	0.3
Leg fat-free mass (left)	0.2	1.0	4.1	1.8	0.7	0.0	-0.7	-0.7	-0.2	1.2	0.4	0.4	0.1	0.9	-1.3	2.0
Maternal smoking around birth	0.2	0.2	1.4	0.1	-0.1	0.1	0.4	-0.5	0.1	0.0	-0.3	0.1	0.9	1.2	0.4	-0.5
Leg predicted mass (left)	0.2	1.0	3.8	1.7	0.6	-0.0	-0.8	-0.7	-0.3	1.2	0.4	0.4	0.2	0.9	-1.4	2.0
Past tobacco smoking	0.2	0.3	1.6	-0.5	-0.6	-0.6	-0.7	0.1	-0.1	-0.4	-0.3	-0.4	0.4	1.3	-1.0	0.2
Financial difficulties in last 2 years	0.2	0.3	1.6	-0.1	-0.4	-0.1	-1.2	-1.0	-0.7	-0.4	-0.5	-0.3	0.4	0.7	0.1	0.0
Trunk fat-free mass	0.2	1.2	4.4	2.0	0.4	0.2	-0.4	-0.4	0.1	1.6	0.9	0.6	0.1	1.2	-1.1	2.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.6	0.2	-0.4	-0.2	0.0	0.2	0.4	0.1	-0.5	0.2	1.3	0.7	-0.5	-0.3
Trunk predicted mass	0.2	1.1	4.2	2.0	0.4	0.2	-0.5	-0.5	0.1	1.5	0.9	0.6	0.1	1.2	-1.1	2.1
Hair/balding pattern: Pattern 4	0.2	0.5	1.6	0.1	0.3	-0.4	-1.3	-0.4	-0.6	1.1	-0.2	0.4	-1.0	-1.0	-0.6	-0.5
Arm fat-free mass (right)	0.2	1.2	4.4	2.1	0.5	0.2	-0.8	-0.5	0.0	1.8	1.0	0.9	-0.2	0.9	-0.9	1.9
Pulse wave peak to peak time	0.2	0.3	1.9	-0.6	-0.4	-0.0	0.2	-0.6	-0.0	0.1	-0.3	0.2	0.0	-0.1	0.8	-1.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.3	-0.5	-0.2	-0.4	0.1	-0.1	-0.7	-0.6	-0.8	-1.1	0.3	-1.0	-0.3	-0.3
Arm predicted mass (right)	0.2	1.2	4.2	2.1	0.4	-0.0	-1.1	-0.4	-0.3	1.7	0.7	0.8	0.0	0.8	-1.1	1.9
Overall health rating	0.2	0.5	1.7	-0.1	-0.4	-0.5	-1.1	-1.3	-0.7	0.3	-0.3	0.1	0.3	-0.5	-1.2	-0.6
Had major operations	0.2	0.3	1.1	0.5	0.4	0.5	0.4	-0.2	0.6	0.6	1.1	0.8	0.3	0.1	0.2	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.9	0.1	-0.5	-0.3	0.7	0.8	0.0	0.1	-0.4	-0.1	0.7	-0.2	-0.9	-0.5
Whole body fat-free mass	0.2	1.1	3.9	1.8	0.5	0.0	-0.7	-0.8	-0.1	1.3	0.7	0.5	0.2	1.1	-1.5	2.0
Leg fat-free mass (right)	0.2	1.0	3.8	1.4	0.4	0.0	-0.8	-1.4	0.1	0.7	0.4	0.3	0.5	1.3	-2.0	1.5
Medication for cholesterol	0.2	0.3	1.3	-0.2	0.6	0.1	0.4	0.0	0.6	0.0	0.1	0.1	0.8	1.2	-0.9	-0.1
Smoking status: Current	0.2	0.3	0.9	-0.2	-0.9	-0.5	-0.6	0.4	-0.2	-0.6	-0.3	-0.5	0.7	0.9	0.5	-0.6
Whole body water mass	0.2	1.1	3.8	1.8	0.4	0.0	-0.7	-0.9	-0.0	1.3	0.7	0.5	0.2	1.1	-1.5	1.9
Leg predicted mass (right)	0.2	1.0	3.6	1.3	0.4	0.0	-0.8	-1.5	0.1	0.7	0.3	0.3	0.4	1.3	-1.9	1.5
Number of self-reported non-cancer illnesses	0.2	0.3	0.8	0.8	0.5	-0.0	0.3	-0.3	-0.4	0.9	-0.5	0.5	0.8	0.0	-0.8	0.0
High cholesterol (Self-reported)	0.2	0.4	1.7	-0.2	-0.4	-0.2	-1.0	-1.3	-0.6	-0.0	-0.5	0.1	0.2	0.3	1.3	-0.7
Medication: Bendroflumethiazide	0.2	0.3	1.2	-0.1	-0.7	-0.5	-1.1	0.1	-0.6	-0.2	-0.7	-0.2	0.6	0.8	0.6	-0.1
Medication: Lisinopril	0.2	0.3	1.0	0.3	0.3	-0.3	-0.6	0.2	-0.6	0.4	-0.3	0.2	-1.0	-0.8	0.5	0.3
Arm fat-free mass (left)	0.2	0.8	2.8	1.7	0.3	-0.1	-1.0	-0.4	-0.3	1.5	0.6	0.6	-0.3	0.6	-0.3	1.6
Pain experienced in last month	0.2	0.3	1.4	-0.2	-0.4	-0.2	0.6	1.2	0.0	-0.5	-0.6	-0.7	0.5	0.1	0.3	0.4
Arm predicted mass (left)	0.2	0.8	2.4	1.6	0.1	-0.4	-1.2	-0.5	-0.6	1.4	0.4	0.4	-0.0	0.4	-0.7	1.5
Worry (Nagel 2018)	0.1	0.2	0.9	0.2	0.6	0.5	-0.3	0.1	0.1	0.1	1.0	0.5	-0.7	-0.3	-0.1	0.3
Reaction Time	0.1	0.2	1.5	-0.5	0.0	0.4	0.1	-0.3	0.5	-0.1	0.3	-0.1	-0.6	0.5	-1.2	-0.2
Systolic Blood Pressure	0.1	0.7	2.2	0.5	-0.5	-1.1	0.0	-0.1	-0.7	0.5	-1.1	-0.4	1.1	-0.9	-1.5	0.9
Hair Pigment	0.1	2.7	7.8	1.5	1.3	2.3	2.5	0.9	2.1	0.4	1.7	1.1	-2.8	-0.6	0.9	1.1
Number of treatments/medications taken	0.1	0.2	0.6	0.8	0.1	0.3	-0.4	-0.2	-0.1	0.6	0.1	0.5	-0.6	0.2	-0.4	0.6
Taking other prescription medications	0.1	0.1	0.5	0.2	-0.5	0.1	0.3	0.2	0.3	0.4	-0.1	0.2	0.5	0.7	0.2	-0.5
Medication: Paracetamol	0.1	0.2	1.0	0.1	0.1	0.1	-0.7	-0.3	-0.1	0.4	-0.2	1.0	-0.4	0.7	-0.7	-0.0
Headache pain in last month	0.1	0.1	0.5	0.7	0.0	-0.0	0.1	-0.4	-0.1	0.7	0.1	0.0	0.2	0.5	0.1	0.4
Osteoporosis (self-reported)	0.1	0.2	0.5	-0.3	-0.4	-0.1	0.5	0.3	0.5	-0.7	0.1	-0.4	-0.5	0.1	0.6	0.2
Illnesses of father: None of the above (group 1)	0.1	0.2	0.6	0.3	0.2	0.1	-0.0	0.6	-0.5	0.2	-0.1	0.3	0.8	0.7	-0.2	0.5
Ever taken oral contraceptive pill	0.1	0.1	0.5	0.1	0.2	-0.0	-0.2	0.1	-0.5	0.2	-0.7	0.1	0.2	-0.1	0.2	0.1
Mother’s age at death	0.1	0.1	0.6	0.2	0.4	0.3	0.2	0.2	0.2	0.4	-0.0	0.4	-0.2	0.4	0.8	-0.3
Tanning	0.0	0.5	4.0	0.3	0.4	0.7	0.7	0.1	0.2	0.0	0.3	0.7	-0.6	-2.0	-0.4	0.1

Hub : Genes

RN7SL417P

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Trait associations