[Hub]/) : Traits : Diastolic blood pressure, automated reading :

chr20:61,522,825-62,912,463

Best TWAS P=1.14e-10 · Best GWAS P=1.53e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LIME1 0.04 0.00 bslmm 439 0.01 3.3e-02 -5.9 6.1 1.3e-09 -0.04 0.07 0.75 FALSE
2 GTEx Adipose Subcutaneous TCEA2 0.11 0.06 lasso 2 0.03 9.4e-04 6.4 6.3 4.1e-10 0.99 0.00 1.00 TRUE
3 GTEx Artery Aorta TCEA2 0.09 0.04 lasso 3 0.03 1.3e-02 -3.3 5.4 8.2e-08 0.65 0.04 0.91 FALSE
4 GTEx Brain Cerebellar Hemisphere STMN3 0.39 0.08 lasso 5 0.22 2.1e-06 -5.4 -5.3 1.4e-07 0.03 0.21 0.48 FALSE
5 GTEx Brain Cerebellum STMN3 0.33 0.12 lasso 10 0.20 1.8e-06 -5.9 -5.5 3.4e-08 -0.03 0.10 0.87 FALSE
6 GTEx Brain Cortex STMN3 0.25 0.09 lasso 7 0.11 6.8e-04 -5.7 -6.2 6.4e-10 0.03 0.08 0.74 FALSE
7 GTEx Breast Mammary Tissue GMEB2 0.18 0.02 lasso 5 0.06 3.0e-04 -5.9 -6.4 1.1e-10 -0.26 0.04 0.75 TRUE
8 GTEx Breast Mammary Tissue (Female) GMEB2 0.36 0.06 lasso 4 0.05 1.2e-02 -5.1 -5.7 1.0e-08 -0.05 0.07 0.60 FALSE
9 GTEx Thyroid SLC2A4RG 0.12 0.06 lasso 5 0.04 2.4e-04 -5.9 5.8 7.9e-09 -0.04 0.05 0.94 FALSE
10 METSIM Adipose DNAJC5 0.03 0.00 blup 201 0.01 2.0e-02 -4.0 -5.5 4.2e-08 0.02 0.03 0.78 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TNFRSF6B 0.03 0.01 blup 44 0.02 7.1e-04 -5.9 -5.6 2.8e-08 0.01 0.01 0.96 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC2A4RG 0.03 0.01 blup 48 0.02 2.4e-03 -5.9 5.7 1.3e-08 -0.01 0.01 0.92 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma LIME1 0.02 0.03 blup 47 0.02 6.2e-03 -5.7 -6.3 2.3e-10 0.01 0.02 0.81 TRUE
14 The Cancer Genome Atlas Brain Lower Grade Glioma ZGPAT 0.05 0.04 blup 60 0.05 7.2e-07 -5.9 5.8 6.3e-09 -0.01 0.01 0.99 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma TNFRSF6B 0.02 0.01 enet 7 0.01 6.9e-03 -5.8 -5.5 4.3e-08 0.05 0.01 0.89 FALSE
16 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RTEL1 0.05 0.04 blup 56 0.03 4.2e-03 -3.7 -5.6 2.5e-08 0.08 0.03 0.47 FALSE
17 The Cancer Genome Atlas Pancreatic Adenocarcinoma RGS19 0.11 0.00 blup 48 0.03 1.7e-02 6.1 -5.8 5.3e-09 -0.76 0.01 0.88 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma SLC2A4RG 0.05 0.01 blup 48 0.02 2.0e-03 -4.5 5.3 1.5e-07 -0.03 0.04 0.80 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma ZGPAT 0.05 0.06 lasso 3 0.06 5.5e-07 -5.7 5.7 1.3e-08 -0.06 0.01 0.99 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma LIME1 0.05 0.03 blup 47 0.04 3.9e-05 -5.9 -5.2 1.9e-07 0.06 0.01 0.99 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma ZGPAT 0.05 0.04 blup 60 0.03 2.3e-04 -5.9 6.0 1.5e-09 0.00 0.01 0.99 FALSE