[Hub]/) : Traits : Diastolic blood pressure, automated reading : ← →

chr20:61,522,825-62,912,463

Best TWAS P=1.14e-10 · Best GWAS P=1.53e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LIME1	0.04	0.00	bslmm	439	0.01	3.3e-02	-5.9	6.1	1.3e-09	-0.04	0.07	0.75	FALSE
2	GTEx	Adipose Subcutaneous	TCEA2	0.11	0.06	lasso	2	0.03	9.4e-04	6.4	6.3	4.1e-10	0.99	0.00	1.00	TRUE
3	GTEx	Artery Aorta	TCEA2	0.09	0.04	lasso	3	0.03	1.3e-02	-3.3	5.4	8.2e-08	0.65	0.04	0.91	FALSE
4	GTEx	Brain Cerebellar Hemisphere	STMN3	0.39	0.08	lasso	5	0.22	2.1e-06	-5.4	-5.3	1.4e-07	0.03	0.21	0.48	FALSE
5	GTEx	Brain Cerebellum	STMN3	0.33	0.12	lasso	10	0.20	1.8e-06	-5.9	-5.5	3.4e-08	-0.03	0.10	0.87	FALSE
6	GTEx	Brain Cortex	STMN3	0.25	0.09	lasso	7	0.11	6.8e-04	-5.7	-6.2	6.4e-10	0.03	0.08	0.74	FALSE
7	GTEx	Breast Mammary Tissue	GMEB2	0.18	0.02	lasso	5	0.06	3.0e-04	-5.9	-6.4	1.1e-10	-0.26	0.04	0.75	TRUE
8	GTEx	Breast Mammary Tissue (Female)	GMEB2	0.36	0.06	lasso	4	0.05	1.2e-02	-5.1	-5.7	1.0e-08	-0.05	0.07	0.60	FALSE
9	GTEx	Thyroid	SLC2A4RG	0.12	0.06	lasso	5	0.04	2.4e-04	-5.9	5.8	7.9e-09	-0.04	0.05	0.94	FALSE
10	METSIM	Adipose	DNAJC5	0.03	0.00	blup	201	0.01	2.0e-02	-4.0	-5.5	4.2e-08	0.02	0.03	0.78	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TNFRSF6B	0.03	0.01	blup	44	0.02	7.1e-04	-5.9	-5.6	2.8e-08	0.01	0.01	0.96	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC2A4RG	0.03	0.01	blup	48	0.02	2.4e-03	-5.9	5.7	1.3e-08	-0.01	0.01	0.92	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIME1	0.02	0.03	blup	47	0.02	6.2e-03	-5.7	-6.3	2.3e-10	0.01	0.02	0.81	TRUE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZGPAT	0.05	0.04	blup	60	0.05	7.2e-07	-5.9	5.8	6.3e-09	-0.01	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	TNFRSF6B	0.02	0.01	enet	7	0.01	6.9e-03	-5.8	-5.5	4.3e-08	0.05	0.01	0.89	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RTEL1	0.05	0.04	blup	56	0.03	4.2e-03	-3.7	-5.6	2.5e-08	0.08	0.03	0.47	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RGS19	0.11	0.00	blup	48	0.03	1.7e-02	6.1	-5.8	5.3e-09	-0.76	0.01	0.88	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC2A4RG	0.05	0.01	blup	48	0.02	2.0e-03	-4.5	5.3	1.5e-07	-0.03	0.04	0.80	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZGPAT	0.05	0.06	lasso	3	0.06	5.5e-07	-5.7	5.7	1.3e-08	-0.06	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	LIME1	0.05	0.03	blup	47	0.04	3.9e-05	-5.9	-5.2	1.9e-07	0.06	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	ZGPAT	0.05	0.04	blup	60	0.03	2.3e-04	-5.9	6.0	1.5e-09	0.00	0.01	0.99	FALSE