[Hub]/) : Traits : Diastolic blood pressure, automated reading :

chr2:134,513,621-137,435,625

Best TWAS P=5.23e-09 · Best GWAS P=4.45e-08 conditioned to 0.915

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC100129961 0.17 0.14 enet 9 0.14 2.6e-17 5.3 5.8 5.2e-09 0.93 0.03 0.97 TRUE
2 GTEx Brain Cerebellar Hemisphere AC016725.4 0.27 0.18 lasso 4 0.24 8.3e-07 -5.4 5.4 6.1e-08 0.63 0.03 0.92 FALSE
3 GTEx Nerve Tibial AC016725.4 0.15 0.06 lasso 6 0.02 8.1e-03 -5.4 5.5 3.1e-08 0.64 0.04 0.96 FALSE
4 GTEx Testis CCNT2 0.31 0.26 lasso 6 0.26 9.3e-12 -5.2 -5.2 2.6e-07 -0.60 0.02 0.98 FALSE
5 GTEx Testis AC016725.4 0.18 0.09 lasso 6 0.09 6.3e-05 5.2 -5.2 1.6e-07 -0.94 0.05 0.95 FALSE
6 GTEx Thyroid CCNT2 0.09 0.10 lasso 2 0.09 1.8e-07 -5.4 -5.3 9.0e-08 -0.61 0.03 0.97 FALSE
7 ROSMAP Brain Pre-frontal Cortex CCNT2 0.06 0.03 enet 27 0.05 1.6e-06 -4.9 -5.4 6.4e-08 -0.70 0.06 0.94 FALSE
8 ROSMAP Brain Pre-frontal Cortex TMEM163 0.19 0.16 lasso 14 0.23 6.2e-29 -3.5 5.5 4.5e-08 0.68 0.92 0.05 FALSE
9 YFS Blood DARS 0.17 0.19 enet 36 0.19 8.2e-60 -4.8 -5.3 1.1e-07 -0.39 0.02 0.97 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ACMSD 0.04 0.01 blup 46 0.02 2.2e-03 -5.4 -5.7 1.5e-08 -0.87 0.02 0.88 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma DARS 0.04 0.02 blup 40 0.01 2.1e-02 -5.0 -5.5 4.3e-08 -0.42 0.01 0.94 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma DARS 0.22 0.15 enet 13 0.19 4.1e-18 -4.7 -5.3 1.4e-07 -0.31 0.03 0.96 FALSE