Best TWAS P=2.99e-10 · Best GWAS P=4.46e-11 conditioned to 1.77e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ZNF827 | 0.13 | 0.14 | enet | 11 | 0.10 | 6.5e-06 | 4.4 | -5.1 | 2.7e-07 | 0.01 | 0.28 | 0.70 | TRUE |
| 2 | GTEx | Vagina | HHIP-AS1 | 0.16 | 0.10 | lasso | 7 | 0.06 | 1.8e-02 | -4.9 | -5.5 | 3.6e-08 | 0.79 | 0.03 | 0.75 | FALSE |
| 3 | NTR | Blood | MMAA | 0.04 | 0.00 | bslmm | 343 | 0.01 | 1.1e-04 | 2.3 | -6.3 | 3.0e-10 | 0.42 | 0.09 | 0.35 | TRUE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | OTUD4 | 0.15 | 0.06 | blup | 31 | 0.05 | 8.3e-03 | -4.3 | 5.4 | 6.3e-08 | -0.80 | 0.01 | 0.50 | FALSE |