Hub : Genes

CASP9

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0890 0.0260 5.6e-07 0.068 0.057 0.072 0.054 0.074 1.1e-08 1.9e-07 4.0e-09 3.2e-07 2.3e-09
2 GTEx Adipose Subcutaneous 0.1060 0.0330 6.8e-05 0.120 NA 0.110 NA 0.107 5.2e-10 NA 2.9e-09 NA 4.8e-09
3 GTEx Adipose Visceral Omentum 0.1040 0.0440 6.0e-03 0.046 NA 0.038 NA 0.054 1.9e-03 NA 4.7e-03 NA 8.9e-04
4 GTEx Artery Aorta 0.1310 0.0550 7.9e-03 0.025 NA 0.006 NA 0.026 1.5e-02 NA 1.4e-01 NA 1.4e-02
5 GTEx Artery Coronary 0.1520 0.0650 7.6e-03 0.115 NA 0.037 NA 0.039 1.1e-04 NA 2.2e-02 NA 1.8e-02
6 GTEx Breast Mammary Tissue 0.1420 0.0470 8.2e-04 0.152 NA 0.100 NA 0.144 3.1e-08 NA 8.4e-06 NA 7.2e-08
7 GTEx Breast Mammary Tissue (Male) 0.0925 0.0730 1.4e-01 0.029 NA 0.001 NA 0.037 7.3e-02 NA 3.0e-01 NA 4.9e-02
8 GTEx Breast Mammary Tissue (Female) 0.1584 0.0754 3.0e-02 0.116 NA 0.074 NA 0.089 2.5e-04 NA 3.1e-03 NA 1.3e-03
9 GTEx Cells Transformed fibroblasts 0.2300 0.0490 4.2e-08 0.139 NA 0.133 NA 0.138 1.5e-10 NA 3.7e-10 NA 1.5e-10
10 GTEx Colon Sigmoid 0.2120 0.0820 1.3e-03 -0.007 NA 0.013 NA 0.013 7.5e-01 NA 1.1e-01 NA 1.1e-01
11 GTEx Esophagus Mucosa 0.1660 0.0410 1.6e-06 0.105 NA 0.158 NA 0.157 1.7e-07 NA 1.0e-10 NA 1.1e-10
12 GTEx Esophagus Muscularis 0.1580 0.0430 5.9e-06 0.154 NA 0.107 NA 0.141 1.2e-09 NA 5.0e-07 NA 6.7e-09
13 GTEx Heart Atrial Appendage 0.2530 0.0590 2.8e-07 0.210 NA 0.246 NA 0.242 8.2e-10 NA 2.1e-11 NA 3.2e-11
14 GTEx Heart Left Ventricle 0.2248 0.0544 2.0e-06 0.128 NA 0.209 NA 0.200 2.6e-07 NA 2.3e-11 NA 6.4e-11
15 GTEx Liver 0.4630 0.1010 4.3e-05 0.190 NA 0.130 NA 0.215 5.4e-06 NA 1.8e-04 NA 1.1e-06
16 GTEx Lung 0.1590 0.0405 4.3e-06 0.102 NA 0.114 NA 0.110 3.4e-08 NA 4.9e-09 NA 8.9e-09
17 GTEx Muscle Skeletal 0.0703 0.0245 1.1e-03 0.049 NA 0.054 NA 0.066 1.5e-05 NA 4.6e-06 NA 4.5e-07
18 GTEx Nerve Tibial 0.0948 0.0358 2.4e-03 0.090 NA 0.010 NA 0.035 6.7e-07 NA 6.4e-02 NA 1.6e-03
19 GTEx Ovary 0.3340 0.1120 2.0e-03 0.071 NA 0.004 NA 0.060 8.0e-03 NA 2.5e-01 NA 1.4e-02
20 GTEx Pancreas 0.2650 0.0680 6.1e-06 0.160 NA 0.154 NA 0.166 2.8e-07 NA 4.8e-07 NA 1.6e-07
21 GTEx Prostate 0.3000 0.1060 1.5e-03 0.033 NA -0.011 NA 0.029 5.1e-02 NA 8.4e-01 NA 6.3e-02
22 GTEx Spleen 0.3390 0.0980 3.6e-04 0.241 NA 0.158 NA 0.216 7.3e-07 NA 7.3e-05 NA 3.0e-06
23 GTEx Stomach 0.2450 0.0680 2.3e-05 0.056 NA 0.106 NA 0.101 1.1e-03 NA 9.4e-06 NA 1.5e-05
24 GTEx Testis 0.2130 0.0650 4.7e-05 0.146 NA 0.120 NA 0.138 5.2e-07 NA 5.6e-06 NA 1.1e-06
25 GTEx Thyroid 0.1670 0.0450 2.8e-07 0.064 NA 0.105 NA 0.099 1.2e-05 NA 2.2e-08 NA 5.0e-08
26 GTEx Uterus 0.4840 0.1110 3.5e-05 0.193 NA 0.191 NA 0.223 9.3e-05 NA 1.0e-04 NA 2.5e-05
27 METSIM Adipose 0.1092 0.0242 5.4e-11 0.065 0.100 0.090 0.104 0.086 4.6e-10 9.5e-15 2.3e-13 3.1e-15 9.1e-13
28 ROSMAP Brain Pre-frontal Cortex 0.0477 0.0204 5.3e-03 0.016 0.013 0.018 0.017 0.017 3.5e-03 8.0e-03 2.1e-03 2.3e-03 2.8e-03
29 YFS Blood 0.0438 0.0126 4.3e-09 0.040 0.027 0.044 0.038 0.043 5.3e-13 2.2e-09 3.7e-14 1.3e-12 6.7e-14
30 TCGA Bladder Urothelial Carcinoma 0.0460 0.0240 3.8e-05 0.053 0.061 0.048 NA 0.022 2.8e-05 6.7e-06 5.8e-05 NA 4.9e-03
31 TCGA Breast Invasive Carcinoma 0.0814 0.0347 2.1e-11 0.059 0.060 0.047 NA 0.060 3.6e-12 2.4e-12 5.4e-10 NA 2.9e-12
32 TCGA Colon Adenocarcinoma 0.1480 0.0700 3.5e-06 0.104 0.105 0.100 NA 0.093 1.4e-06 1.2e-06 2.1e-06 NA 5.0e-06
33 TCGA Head and Neck Squamous Cell Carcinoma 0.0454 0.0264 2.4e-04 0.033 0.027 0.020 NA 0.027 1.2e-04 5.0e-04 2.2e-03 NA 4.9e-04
34 TCGA Kidney Renal Clear Cell Carcinoma 0.0616 0.0344 3.9e-05 0.036 0.045 0.037 NA 0.039 5.2e-05 7.3e-06 4.8e-05 NA 2.9e-05
35 TCGA Kidney Renal Papillary Cell Carcinoma 0.0890 0.0430 4.4e-05 0.065 0.057 0.080 NA 0.061 1.4e-04 3.5e-04 2.6e-05 NA 2.3e-04
36 TCGA Brain Lower Grade Glioma 0.0341 0.0176 1.9e-04 0.039 0.042 0.038 NA 0.041 2.4e-05 1.4e-05 3.2e-05 NA 1.9e-05
37 TCGA Lung Adenocarcinoma 0.0723 0.0419 1.6e-04 0.029 0.032 0.022 NA 0.019 2.4e-04 1.2e-04 1.2e-03 NA 2.5e-03
38 TCGA Lung Squamous Cell Carcinoma 0.0293 0.0183 2.0e-03 0.018 0.008 0.010 NA 0.008 3.7e-03 3.6e-02 2.2e-02 NA 3.9e-02
39 TCGA Pancreatic Adenocarcinoma 0.1240 0.0620 8.5e-04 0.016 0.051 0.022 NA 0.019 7.1e-02 3.6e-03 4.2e-02 NA 5.1e-02
40 TCGA Prostate Adenocarcinoma 0.1960 0.0705 0.0e+00 0.179 0.201 0.175 NA 0.180 2.4e-18 1.2e-20 5.2e-18 NA 1.7e-18
41 TCGA Soft Tissue Sarcoma 0.0540 0.0370 5.6e-03 0.022 0.025 0.000 NA 0.019 1.7e-02 1.2e-02 3.0e-01 NA 2.4e-02
42 TCGA Testicular Germ Cell Tumors 0.3660 0.1400 3.3e-03 0.038 0.017 0.044 NA 0.065 1.8e-02 8.3e-02 1.1e-02 NA 2.6e-03
43 TCGA Thyroid Carcinoma 0.1390 0.0510 8.2e-14 0.133 0.152 0.149 NA 0.154 6.5e-13 1.2e-14 2.3e-14 NA 8.8e-15

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43
Bipolar Disorder (2018) 0.9 1.5 3.8 -1.1 1.5 1.1 1.3 1.4 1.3 2.0 1.3 1.1 1.0 1.5 1.4 1.3 1.3 1.3 1.0 1.3 1.3 0.9 1.7 1.6 1.9 0.4 -1.0 0.7 1.0 1.4 0.3 -0.3 1.4 0.2 0.9 1.0 1.0 1.3 1.4 1.0 1.0 1.1 1.2 1.3 0.3 1.3
Bipolar Disorder or Schizophrenia 0.7 1.6 4.2 -1.1 1.6 1.6 1.2 1.7 1.4 2.1 1.3 1.3 0.2 1.5 1.4 1.6 1.4 1.0 1.5 1.3 1.3 1.0 1.6 1.6 2.0 0.8 -1.1 0.8 1.0 1.6 0.2 -0.3 1.4 0.6 1.2 1.0 1.2 1.3 1.3 1.5 1.0 1.3 1.3 1.3 0.4 1.3
Depressed Affect (Nagel 2018) 0.8 1.7 6.8 1.8 -1.4 -2.5 0.3 -1.4 -1.4 -1.6 -0.2 0.4 -0.0 -0.9 -1.4 -1.5 -0.1 -1.1 -1.0 -0.5 -1.4 -1.8 -1.2 -2.1 -1.5 -2.6 2.3 -2.2 -2.0 -0.2 0.1 2.1 -0.9 1.6 0.8 0.5 0.3 -0.2 -0.0 -0.3 0.4 0.4 -0.8 -0.2 -0.2 -0.2
Depression (Nagel 2018) 0.3 0.5 2.6 0.3 0.1 -1.6 0.7 -0.3 0.1 -0.6 0.5 0.4 0.2 0.2 0.1 -0.3 0.7 0.3 -0.0 0.4 0.0 -0.5 0.3 -0.5 -0.6 -1.2 0.8 0.6 -1.0 0.2 1.2 0.9 0.2 0.8 1.2 0.7 1.2 0.5 0.8 -0.1 1.0 1.0 0.4 0.5 1.1 0.5
Intelligence (Savage-Jansen 2018) 1.1 3.5 10.2 -1.2 1.5 0.3 2.4 1.1 1.6 1.5 2.3 2.5 1.3 2.0 1.6 1.4 2.4 0.7 1.2 2.3 1.7 1.1 1.6 1.0 1.4 1.2 0.0 1.1 0.7 1.3 2.4 1.1 2.2 1.9 2.4 2.5 2.2 2.3 2.3 3.2 2.5 2.6 2.2 2.6 -0.7 2.3
Neuroticism (Nagel 2018) 0.5 1.1 5.6 1.4 -1.0 -1.6 0.5 -0.8 -1.0 -1.0 0.2 0.7 0.4 -0.7 -1.0 -0.9 0.3 -1.1 -0.6 -0.2 -1.1 -1.4 -0.8 -1.6 -0.9 -2.4 2.2 -1.4 -1.6 0.2 0.3 2.0 -0.5 1.6 1.0 0.7 0.6 0.0 0.4 -0.2 0.9 0.8 -0.7 0.2 -0.1 0.2
Schizophrenia (2018) 0.2 0.5 1.3 -0.5 0.8 1.1 0.5 1.0 0.7 1.1 0.6 0.8 -0.5 0.7 0.7 0.9 0.7 0.1 1.1 0.7 0.7 0.5 0.7 0.7 1.1 0.7 -0.6 0.7 0.5 0.9 0.1 -0.1 0.7 0.6 0.8 0.5 0.7 0.6 0.6 1.1 0.4 0.7 0.7 0.6 0.2 0.6
Schizophrenia vs Biploar Disorder 0.2 0.2 1.3 -0.6 0.3 0.9 0.2 0.2 0.5 0.2 0.3 0.2 0.1 0.4 0.6 0.3 0.2 0.6 0.6 0.3 0.5 0.4 0.4 0.2 0.1 0.9 -0.6 -0.1 0.8 1.1 -0.2 -0.3 0.4 -0.1 0.3 0.1 0.2 0.3 0.3 0.4 -0.1 0.4 0.7 0.3 -0.0 0.3
Worry (Nagel 2018) 1.2 2.5 5.5 -1.1 1.4 0.8 1.8 1.8 1.4 1.6 1.9 2.0 1.4 1.6 1.5 1.7 2.4 1.0 2.0 1.8 1.4 0.7 1.7 0.6 1.8 0.3 0.2 0.9 1.0 2.3 1.5 0.6 1.9 0.9 2.0 1.8 2.0 1.9 2.1 1.4 2.2 1.9 1.4 2.0 0.1 1.9
Alzheimer’s Disease (in mother) 0.4 0.5 1.6 -0.8 0.7 -0.2 0.5 0.1 0.9 1.1 0.7 0.6 -0.2 0.8 0.9 0.6 0.9 0.7 0.4 0.7 0.9 1.1 0.6 0.7 1.1 1.3 -1.0 1.1 0.8 0.7 0.5 -0.6 1.0 -0.5 0.0 0.4 0.5 0.6 0.6 0.4 0.6 0.3 0.4 0.8 0.2 0.6
Alzheimer’s Disease (in father) 0.6 0.7 2.3 0.2 0.2 -1.0 1.3 0.7 0.3 0.6 1.0 1.2 0.0 0.7 0.2 0.4 0.4 0.7 0.5 0.9 0.2 -0.6 0.0 0.2 0.5 -0.3 0.8 -1.0 -0.3 0.9 1.4 0.9 0.5 1.3 1.5 1.3 1.3 1.0 0.8 1.0 1.0 0.9 0.8 0.7 0.8 1.0
Alzheimer’s Disease (including proxy) 0.2 0.3 1.2 -0.6 0.6 -0.5 0.4 0.5 0.7 1.1 0.5 0.5 0.4 0.6 0.6 0.6 0.5 0.8 0.3 0.6 0.7 0.6 0.4 0.8 1.1 0.8 -0.5 0.1 0.6 0.7 0.7 -0.7 0.7 -0.4 0.1 0.4 0.4 0.5 0.3 0.3 0.3 0.0 0.3 0.4 0.3 0.5
Crohns Disease (2017) 1.7 3.8 10.1 1.7 -2.2 0.6 -2.2 -2.4 -2.2 -1.9 -2.5 -2.0 -3.2 -2.4 -2.1 -2.3 -2.4 -1.8 -1.6 -2.5 -2.1 -1.9 -2.3 -2.2 -2.0 -0.5 0.7 -1.0 -0.8 -1.7 -1.1 1.2 -2.3 0.4 -1.2 -2.0 -1.5 -2.4 -1.9 -1.8 -2.4 -1.4 -1.6 -2.1 2.2 -2.4
Irritable Bowel Disease (IBD) 0.3 0.7 12.3 -0.1 -0.3 1.9 -0.6 -0.4 -0.3 0.0 -0.7 -0.4 -2.2 -0.5 -0.3 -0.3 -0.5 -0.1 0.2 -0.6 -0.3 -0.2 -0.6 -0.5 -0.2 0.9 -0.4 0.1 0.8 -0.2 -0.1 1.1 -0.3 0.7 0.2 -0.6 0.2 -0.6 0.0 -0.5 -1.0 0.4 0.5 -0.2 3.5 -0.6
Ulcerative Colitis (UC) 1.4 2.7 13.1 -1.7 1.6 2.4 1.4 1.6 1.6 1.8 1.4 1.3 -0.3 1.5 1.5 1.7 1.5 1.6 2.0 1.5 1.6 1.3 1.2 1.3 1.8 1.8 -1.0 1.1 1.8 1.2 0.9 0.8 1.7 1.1 1.8 1.1 2.0 1.4 2.0 1.2 0.9 2.1 2.4 1.7 3.6 1.4
Major Depression (MDD) 0.5 0.6 2.6 -0.6 0.1 0.7 -0.9 1.0 0.3 1.0 -0.5 -0.6 0.5 -0.3 0.3 0.7 -0.3 0.4 0.3 -0.4 0.3 1.3 0.8 1.0 1.2 0.3 -1.0 -0.1 1.0 0.5 -0.2 -1.6 -0.0 -1.3 -0.9 -1.0 -0.9 -0.6 -0.6 -0.6 -1.0 -1.0 -0.4 -0.6 -0.4 -0.5
Reaction Time 0.8 1.5 3.7 -0.7 1.1 0.9 1.3 0.8 1.0 0.8 1.3 1.5 -0.9 1.2 1.0 0.9 1.3 0.7 1.4 1.3 1.0 0.2 1.4 0.3 0.7 0.9 -0.4 1.3 0.8 1.6 1.9 1.2 1.2 1.4 1.9 1.4 1.9 1.3 1.3 1.7 1.3 1.8 1.7 1.4 1.1 1.3
Verbal and Numeric Reasoning (VNR) 0.9 2.1 4.2 -1.7 1.8 -0.2 1.5 1.1 1.8 1.7 1.7 1.3 1.5 1.7 1.8 1.6 1.8 1.0 1.0 1.8 1.8 2.1 1.9 1.7 1.6 1.1 -1.1 1.7 1.3 0.8 1.4 -1.0 1.7 -0.4 0.7 1.3 1.0 1.7 1.5 1.6 1.4 1.3 1.6 1.7 -0.4 1.7
Breast Cancer 0.5 1.2 5.3 -0.6 0.1 -0.1 -1.8 0.7 0.0 0.4 -1.3 -1.7 0.1 -0.9 0.1 0.3 -0.7 -0.3 0.1 -1.0 0.1 0.9 0.4 0.4 0.6 1.2 -2.3 1.9 0.6 -0.2 -0.8 -1.6 -0.5 -1.9 -1.8 -1.9 -1.4 -1.3 -1.0 -1.5 -1.6 -1.2 -0.5 -0.8 1.1 -1.3
Ovarian Cancer 0.3 0.3 1.3 0.6 -0.5 -1.1 -0.4 -0.4 -0.5 -0.5 -0.6 -0.5 0.0 -0.4 -0.5 -0.5 -0.5 0.5 -0.7 -0.6 -0.5 -0.6 -0.9 -0.3 -0.4 -0.4 0.4 0.6 -0.7 -0.9 -0.4 -0.2 -0.7 -0.3 -0.5 -0.6 -0.5 -0.6 -0.8 -0.6 -0.5 -0.9 -0.7 -0.8 -0.5 -0.6
Prostate Cancer 1.2 1.7 4.9 1.6 -1.8 -2.2 -1.1 -0.8 -1.7 -1.5 -1.4 -1.0 -0.1 -1.6 -1.7 -1.5 -1.0 -1.3 -1.5 -1.5 -1.7 -1.8 -1.1 -1.3 -1.5 -1.1 1.0 0.1 -1.4 -1.4 -0.9 0.7 -1.5 0.3 -1.0 -1.0 -1.2 -1.4 -1.3 -1.4 -0.7 -1.2 -1.7 -1.3 0.2 -1.4
Age at First Birth 1.6 2.3 6.8 -1.3 1.7 1.1 1.6 1.4 1.6 1.8 1.9 1.9 0.6 1.9 1.6 1.6 1.7 1.1 1.7 1.9 1.6 0.7 1.3 1.5 1.8 0.9 -1.0 0.4 1.0 2.6 1.4 -0.5 1.7 0.3 1.6 1.8 1.7 1.9 1.4 1.9 1.4 1.1 1.6 1.3 -0.2 1.9
Bipolar Disorder (2011) 1.3 1.3 3.3 -1.4 1.5 0.8 0.8 1.2 1.4 1.8 0.9 0.7 0.3 1.1 1.4 1.4 1.5 0.6 1.2 1.1 1.4 1.3 1.4 1.5 1.8 1.1 -1.6 1.5 1.5 1.3 0.2 -0.7 1.4 -0.5 0.3 0.5 0.8 0.9 1.0 0.9 0.8 0.6 0.9 1.0 0.3 0.9
Body Mass Index (BMI) (2010) 1.3 1.8 5.1 1.5 -1.5 -0.2 -1.1 -1.4 -1.5 -1.1 -1.5 -1.2 -0.6 -1.4 -1.6 -1.4 -1.5 -0.2 -2.0 -1.5 -1.5 -1.1 -1.6 -0.5 -1.0 -1.7 1.0 -0.7 -1.2 -1.1 -1.1 -0.1 -1.6 -0.7 -1.4 -1.3 -1.2 -1.4 -1.5 -2.2 -1.1 -1.8 -1.9 -1.7 1.0 -1.5
Coronary Artery Disease (CAD) 0.3 0.3 2.2 0.7 -0.3 -0.4 0.8 0.2 -0.3 -0.7 0.4 0.5 -0.9 0.1 -0.2 -0.0 0.0 -0.4 -0.0 0.0 -0.4 -0.6 0.1 0.1 -0.2 -1.1 1.5 0.2 -0.7 -0.0 1.1 0.9 -0.1 0.7 0.7 0.7 0.6 0.4 0.2 -0.0 0.9 0.2 -0.4 0.1 -0.4 0.4
Crohns Disease (2012) 2.4 3.9 7.2 1.3 -1.8 0.4 -2.5 -2.4 -1.9 -1.9 -2.6 -2.7 -2.2 -2.3 -1.7 -2.1 -2.5 -1.2 -1.8 -2.5 -1.8 -1.1 -1.8 -1.9 -2.0 -0.3 -0.1 0.8 -0.7 -2.6 -2.3 -0.2 -2.3 -0.9 -2.1 -2.6 -2.2 -2.6 -2.3 -2.1 -2.6 -2.0 -1.9 -2.3 0.7 -2.5
Mean Putamen Volume 0.1 0.1 1.4 -0.0 -0.0 0.4 0.2 0.3 0.0 0.2 0.2 0.3 0.2 0.2 -0.0 0.2 0.4 -0.3 0.2 0.2 0.0 -0.5 -0.2 0.3 0.2 -0.3 0.1 -0.3 0.3 1.2 -0.4 0.2 0.2 0.1 0.2 0.3 0.2 0.2 0.3 -0.2 0.3 0.1 -0.1 0.1 0.4 0.2
Fasting Glucose 1.0 1.2 7.2 -0.9 1.1 -0.4 1.3 0.9 1.1 0.9 -0.1 -0.1 -0.0 1.7 1.1 0.9 1.3 1.3 1.0 1.4 1.1 0.8 1.1 0.9 1.0 1.1 -0.1 0.7 0.9 0.6 -0.0 0.4 1.3 0.8 1.0 1.5 0.8 1.2 1.0 2.7 1.0 1.2 1.3 1.4 -2.2 0.1
HbA1C 1.4 1.5 3.4 1.8 -1.3 -0.5 -1.1 -1.6 -1.6 -1.5 -1.4 -1.0 -1.5 -1.2 -1.4 -1.5 -1.5 -0.6 -1.5 -1.4 -1.7 -1.3 -1.5 -1.2 -1.2 -1.0 1.1 -0.4 -1.2 -1.8 -0.5 0.8 -1.6 0.3 -0.6 -0.9 -0.9 -1.3 -1.3 -1.0 -1.1 -1.0 -1.4 -1.3 -0.2 -1.2
HDL Cholesterol 0.4 0.7 2.3 1.0 -0.9 -0.1 -0.7 -1.2 -1.1 -0.8 -0.7 -0.4 -0.3 -0.9 -1.1 -1.2 -0.6 -1.4 -1.0 -0.7 -1.0 -1.1 -0.9 -1.5 -1.1 -0.5 1.0 -0.5 -0.7 -1.2 -0.2 0.8 -0.9 0.4 -0.3 -0.3 -0.6 -0.7 -0.6 -0.5 -0.4 -0.4 -1.0 -0.7 -0.0 -0.8
LDL Cholesterol 1.1 1.7 5.7 -0.3 0.8 -0.0 1.9 0.5 0.9 0.9 1.7 1.7 0.1 1.4 1.0 0.7 1.4 0.9 1.0 1.5 0.8 0.3 1.2 0.5 0.9 -0.1 0.4 0.3 0.5 1.2 1.6 1.4 1.5 1.5 1.8 1.8 2.0 1.7 1.9 1.3 2.4 2.1 1.2 2.0 0.3 1.8
Lupus 2.7 4.1 12.0 0.3 -1.2 0.7 -2.9 -0.7 -1.2 -1.4 -2.9 -3.2 -1.5 -2.2 -1.2 -1.1 -2.4 -0.4 -1.4 -2.6 -1.2 0.4 -1.4 -0.3 -1.4 0.4 -1.6 -0.2 0.1 -2.1 -2.5 -1.8 -2.1 -2.2 -3.0 -3.4 -2.9 -2.9 -2.8 -2.4 -3.5 -2.8 -1.6 -2.7 0.1 -2.8
Neuroticism (2016) 0.5 0.7 6.4 0.8 -0.3 0.3 1.0 -0.6 -0.3 -0.5 0.6 1.2 -2.5 0.3 -0.3 -0.4 0.4 -0.1 0.1 0.4 -0.4 -0.7 -0.5 -1.0 -0.6 -0.9 1.6 -0.5 -0.2 0.2 0.1 2.0 -0.0 1.6 1.3 1.0 0.8 0.5 0.4 1.0 0.8 1.0 0.3 0.6 -0.5 0.7
Primary Biliary Cirrhosis 0.1 0.1 1.7 -0.2 0.0 0.8 -0.4 0.4 -0.0 -0.3 -0.3 -0.5 -0.5 -0.2 0.0 0.3 -0.3 -0.6 0.3 -0.2 0.0 0.0 0.1 0.1 -0.3 0.4 -0.4 0.1 0.2 -0.3 0.0 -0.5 -0.2 -0.4 -0.4 -0.4 -0.7 -0.2 -0.4 0.2 -0.6 -0.3 -0.0 -0.2 -1.3 -0.3
Rheumatoid Arthritis 0.2 0.3 1.8 0.1 -0.4 -1.3 -0.6 -0.2 -0.4 0.1 -0.5 -0.5 -0.4 -0.3 -0.4 -0.3 -0.6 -0.3 -0.4 -0.5 -0.5 -0.3 -0.4 0.6 0.1 -0.4 0.2 -0.5 -0.2 -0.1 -0.0 -0.6 -0.3 -0.4 -0.8 -0.5 -0.8 -0.5 -0.5 -0.6 -0.6 -0.8 -0.7 -0.7 0.0 -0.5
Schizophrenia (2014) 0.5 1.1 3.3 -0.9 1.2 1.8 0.8 1.5 1.0 1.6 0.9 0.9 -0.3 1.0 1.1 1.3 1.0 0.6 1.5 1.0 1.0 0.8 1.0 1.1 1.5 1.2 -0.9 1.1 0.9 1.2 0.4 -0.3 1.0 0.4 0.9 0.7 0.9 0.9 0.9 1.3 0.6 1.0 1.1 0.9 0.6 0.9
Triglycerides 0.1 0.2 1.4 0.2 -0.1 -0.9 0.6 0.3 -0.1 0.0 0.1 0.1 -0.4 -0.0 0.1 0.0 0.1 0.2 -0.3 0.2 -0.1 0.0 0.1 0.4 0.0 -0.6 0.2 -0.2 -0.2 0.2 0.1 0.8 0.1 0.6 0.5 0.1 0.6 0.1 0.5 0.0 0.5 0.8 0.3 0.4 1.2 0.2
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.8 -0.0 -0.4 0.4 -0.2 0.6 -0.3 -0.1 -0.7 -0.9 -0.5 -0.5 -0.6 0.1 -0.6 -0.4 -0.5 -0.8 -0.4 -0.1 -0.4 0.8 0.0 -0.6 -0.1 0.4 -0.7 -1.2 -1.3 -0.7 -0.7 -0.9 -1.0 -1.2 -1.0 -0.8 -0.8 -1.1 -1.0 -1.1 -0.9 -1.0 -0.4 -1.0
Ulcerative Colitis 0.4 0.5 7.3 -0.9 0.6 1.3 0.1 0.5 0.5 0.8 0.1 0.2 0.1 0.2 0.5 0.6 0.4 1.0 0.8 0.2 0.5 0.6 0.6 0.5 0.9 1.2 -0.7 0.7 0.9 -0.1 -0.2 0.4 0.6 0.4 0.4 -0.0 0.5 0.1 0.6 0.1 -0.3 0.7 1.0 0.5 2.7 0.2
Blood Eosinophil Count 0.7 5.1 12.5 1.7 -2.3 -0.2 -2.6 -1.7 -2.4 -2.3 -2.8 -2.6 -0.4 -2.9 -2.3 -2.2 -2.6 -1.8 -3.1 -2.8 -2.4 -1.2 -2.6 -1.9 -2.3 -1.1 0.7 -1.8 -1.4 -3.5 -2.4 0.0 -2.6 -0.6 -2.0 -2.6 -2.4 -2.8 -2.8 -2.4 -3.0 -2.6 -2.3 -3.0 0.1 -2.8
Blood Platelet Count 0.1 1.3 2.6 1.1 -1.4 -0.2 -1.2 -0.0 -1.5 -0.8 -1.5 -0.9 -1.3 -1.6 -1.5 -1.0 -1.3 -1.1 -1.1 -1.5 -1.4 -1.0 -1.6 -1.0 -0.9 -0.5 0.7 -1.5 -0.7 -1.1 -0.6 0.5 -1.2 0.3 -1.1 -1.2 -1.2 -1.5 -1.4 -0.9 -1.4 -1.4 -1.4 -1.4 0.5 -1.5
Blood Red Count 3.7 35.7 57.3 -6.4 6.9 1.9 5.7 6.9 7.0 6.6 6.5 5.2 6.9 6.6 6.9 7.1 7.1 6.3 6.3 6.8 7.1 7.0 7.6 6.6 6.8 5.4 -3.9 4.6 6.0 3.8 4.4 -2.0 7.2 -0.2 4.4 4.9 5.9 6.5 6.8 4.8 5.5 5.9 7.0 6.6 2.7 6.4
Blood White Count 0.2 1.2 5.1 0.7 -0.3 -1.1 1.7 0.5 -0.2 -0.1 1.1 1.7 1.3 0.3 -0.2 -0.0 0.7 -0.7 -0.3 0.9 -0.2 -0.8 -0.1 -0.5 -0.2 -1.5 2.2 -1.3 -0.7 0.4 2.2 1.7 0.5 2.0 1.7 1.7 1.2 1.1 0.7 1.6 1.4 0.8 0.2 0.5 -1.4 1.1
Heel T-Score 2.3 18.3 121.0 -5.5 5.2 11.0 1.9 5.0 5.2 4.7 3.2 1.9 -0.9 4.1 5.2 5.4 3.3 4.8 5.0 3.7 5.3 5.8 4.3 4.0 4.8 6.4 -5.0 3.6 5.4 4.2 0.7 -3.2 4.4 -2.1 1.3 1.6 2.3 3.3 3.0 2.6 1.0 2.3 4.9 3.5 1.2 3.2
BMI 1.8 10.2 28.1 0.6 -2.0 -0.1 -4.8 -1.8 -1.9 -1.7 -4.3 -5.0 -1.9 -3.2 -1.9 -2.1 -3.7 -1.0 -2.6 -3.8 -1.9 -0.2 -2.0 -0.7 -1.6 0.3 -2.5 1.1 0.2 -3.0 -3.0 -3.4 -3.1 -4.4 -5.3 -5.0 -4.6 -4.2 -4.2 -4.7 -4.8 -4.9 -3.2 -4.1 0.5 -4.3
Height 0.5 10.2 19.1 -1.8 2.6 -2.1 3.9 3.2 3.0 3.9 4.0 4.0 3.5 3.4 2.9 3.2 3.6 2.5 3.6 3.9 2.8 1.5 3.2 2.2 3.9 0.8 0.5 1.8 1.8 3.3 3.9 0.7 3.6 1.6 3.5 4.0 4.0 4.0 4.3 2.9 4.4 3.9 3.0 4.0 1.8 4.0
Waist Hip Ratio (WHR) 0.2 1.1 8.6 -0.7 0.4 -0.6 -1.0 0.8 0.4 0.4 -0.7 -1.2 1.4 -0.5 0.4 0.5 -0.1 -0.2 -0.1 -0.4 0.4 1.4 0.5 0.9 0.2 0.1 -1.7 0.4 0.7 -0.2 -2.9 -2.4 -0.2 -2.4 -1.7 -1.4 -1.3 -0.7 -0.7 -1.0 -1.0 -1.1 -0.4 -0.6 -0.6 -0.7
Systolic Blood Pressure 2.1 10.3 44.0 4.6 -2.8 -4.7 2.0 -3.4 -3.1 -3.4 0.6 2.4 -1.6 -1.0 -3.0 -3.4 -0.8 -3.1 -2.3 -0.2 -3.1 -4.3 -2.0 -5.1 -3.4 -5.0 6.6 -3.4 -4.5 -2.0 3.5 6.3 -1.4 5.5 2.9 2.8 1.3 0.6 0.4 2.2 2.5 1.9 -1.7 0.7 -3.8 0.7
Smoking Status 1.5 3.5 8.6 2.7 -2.4 -2.2 -0.9 -2.2 -2.3 -2.4 -1.5 -0.7 -1.5 -1.9 -2.3 -2.5 -2.0 -2.0 -1.8 -1.7 -2.4 -2.9 -2.5 -2.9 -2.5 -1.9 2.3 -2.4 -2.4 -1.0 0.4 2.2 -2.1 1.7 -0.2 -0.7 -0.9 -1.5 -1.5 -0.3 -0.8 -0.6 -1.7 -1.3 -0.9 -1.5
Allergy or Eczema 1.1 3.0 14.7 2.4 -1.6 -3.8 1.4 -1.9 -1.4 -1.1 0.7 1.6 0.3 -0.1 -1.4 -1.6 0.4 -1.6 -0.9 0.3 -1.5 -2.5 -1.1 -2.1 -1.0 -3.1 3.5 -2.6 -2.1 0.1 2.4 2.7 -0.4 2.5 1.6 1.8 1.2 0.7 0.7 0.4 2.2 0.9 -1.1 0.3 -0.7 0.7
Cardiovascular Disease 0.5 1.5 8.4 0.7 0.3 -2.9 1.9 -0.3 0.0 -0.3 1.4 1.6 1.8 0.7 0.2 -0.3 0.7 -0.2 -0.3 1.2 -0.0 -0.2 0.6 -1.0 -0.4 -1.3 1.8 0.7 -0.7 -0.9 1.6 1.6 0.6 1.6 1.5 1.9 1.2 1.4 1.1 1.7 2.0 1.4 0.3 1.2 -1.9 1.5
Hypothyroidism (self reported) 0.1 0.3 1.8 0.2 -0.2 0.1 -0.9 -0.8 -0.2 -0.2 -0.6 -0.7 1.3 -0.7 -0.2 -0.5 -0.6 -0.0 -0.5 -0.5 -0.2 -0.3 -0.6 -0.8 -0.1 0.1 -0.2 0.8 -0.2 -0.0 -0.4 -0.3 -0.4 -0.2 -0.2 -0.6 -0.1 -0.5 -0.5 -0.7 -0.5 -0.5 -0.2 -0.4 0.3 -0.6
Respiratory disease 0.3 0.8 3.0 -0.4 0.6 0.3 1.1 0.3 0.7 0.4 1.2 1.1 0.9 0.9 0.8 0.6 1.1 1.3 0.9 1.1 0.7 0.5 0.7 -0.1 0.3 -0.0 0.5 -0.5 0.4 0.7 1.7 0.3 0.8 0.6 1.1 1.3 1.1 1.2 1.0 1.3 1.1 1.1 1.0 0.9 -0.3 1.2
Type 2 Diabetes (T2D) (2018) 0.5 0.9 2.9 -1.0 1.1 -0.4 0.7 1.1 1.1 0.6 1.0 0.4 1.7 0.9 1.2 1.1 1.1 1.0 0.7 1.0 1.1 1.3 1.0 1.3 0.5 0.5 -0.8 1.1 1.1 0.4 -1.0 -0.5 0.8 -0.8 0.2 0.6 0.9 1.0 1.1 0.0 0.9 0.9 1.0 0.9 1.5 1.0
Lung FEV1/FVC ratio 1.3 6.4 14.2 2.3 -2.6 -0.9 -2.6 -3.8 -2.6 -3.3 -2.9 -2.7 -3.0 -2.9 -2.6 -3.2 -2.9 -2.8 -2.4 -2.9 -2.7 -2.5 -3.2 -3.1 -3.4 -2.1 1.0 -1.8 -2.3 -1.4 -1.8 0.3 -3.0 -0.4 -2.0 -2.6 -2.3 -2.9 -2.7 -2.5 -2.4 -2.1 -2.5 -2.6 -0.2 -2.9
Lung FVC 0.7 3.8 10.2 -2.2 2.4 1.1 1.6 2.7 2.4 2.3 1.8 1.1 2.7 2.2 2.3 2.5 1.7 2.3 1.2 2.0 2.3 3.2 2.7 3.1 2.2 1.5 -1.9 2.6 2.0 -0.5 -0.8 -1.6 2.2 -1.4 0.3 1.1 1.1 1.7 1.8 0.8 1.3 1.3 1.7 2.0 0.4 1.8
Neuroticism 0.5 1.2 5.2 1.4 -1.1 -1.6 0.6 -1.0 -1.0 -1.0 0.2 0.8 0.5 -0.5 -1.0 -1.0 0.3 -0.7 -0.4 -0.1 -1.0 -1.6 -0.9 -1.8 -0.8 -1.9 2.3 -2.0 -1.4 0.3 0.6 2.2 -0.4 1.9 1.2 0.9 0.6 0.2 0.4 0.4 0.9 0.9 -0.4 0.3 -0.7 0.3
Chronotype (morning person) 3.1 7.1 27.9 -0.9 -0.2 0.3 -4.0 -0.8 -0.3 -0.4 -3.1 -4.5 0.8 -2.3 -0.2 -0.4 -2.3 -0.9 -1.8 -2.5 -0.3 2.3 0.4 1.2 -0.6 1.2 -3.4 3.2 1.0 -2.7 -3.3 -4.3 -1.7 -5.3 -5.0 -4.4 -3.6 -3.1 -2.5 -4.5 -3.3 -3.3 -1.8 -2.3 2.4 -3.1
Hair Pigment 0.0 1.2 6.4 1.4 -1.0 -0.6 -0.8 -0.5 -1.0 -1.3 -0.8 -0.7 -2.5 -0.5 -1.0 -0.8 -1.0 -0.3 -1.0 -0.9 -1.1 -1.3 -1.2 -1.3 -1.2 -1.9 2.2 -0.2 -1.6 -0.2 -0.9 0.9 -1.3 0.5 0.2 -0.6 -0.5 -0.9 -1.1 -0.3 -0.5 -0.8 -1.3 -1.1 -1.9 -0.8
Tanning 0.3 3.3 7.2 -2.3 2.2 1.5 1.0 2.5 2.3 2.4 1.4 0.7 1.8 1.8 2.3 2.4 1.4 2.2 2.6 1.6 2.3 1.9 2.4 2.7 2.1 2.5 -2.3 1.2 2.5 1.7 0.7 -1.5 2.0 -1.1 0.3 0.6 1.0 1.4 1.7 0.7 0.8 1.2 2.1 1.7 1.6 1.4
Hand grip strength (left) 0.3 0.8 2.5 -1.1 0.9 0.8 0.7 0.7 1.1 1.3 0.9 0.6 0.1 1.1 1.1 0.9 0.6 0.7 1.2 1.0 1.1 0.7 0.9 0.6 1.3 0.9 -0.9 0.9 1.2 1.6 0.4 -0.7 1.1 -0.6 -0.1 0.6 0.1 0.9 0.9 0.8 0.7 0.6 0.6 1.1 -0.7 0.9
Number of treatments/medications taken 3.0 5.4 9.9 2.7 -2.6 -2.2 -1.8 -2.8 -2.8 -3.0 -2.2 -1.6 -0.3 -2.7 -2.8 -2.9 -2.2 -2.8 -3.1 -2.4 -2.8 -2.0 -2.6 -2.9 -3.1 -2.6 2.5 -1.6 -2.5 -3.0 -1.8 1.5 -2.6 0.4 -1.5 -1.5 -1.9 -2.3 -2.2 -1.8 -1.5 -1.7 -2.6 -2.0 -1.0 -2.2
Average weekly spirits intake 1.7 2.1 4.3 1.7 -1.8 -1.1 -1.3 -1.6 -1.8 -2.1 -1.5 -1.1 -0.3 -1.8 -1.7 -1.8 -1.5 -2.0 -1.2 -1.6 -1.7 -1.7 -1.6 -2.0 -2.0 -1.3 1.1 -1.3 -1.7 -1.0 -0.9 0.4 -1.6 0.1 -0.9 -1.0 -1.3 -1.5 -1.6 -0.9 -0.9 -1.2 -1.9 -1.5 -1.8 -1.4
Sensitivity / hurt feelings 2.9 5.0 13.0 3.0 -2.9 -1.4 -1.0 -2.4 -2.9 -2.6 -1.8 -1.0 -1.4 -2.4 -2.9 -2.8 -1.9 -2.3 -2.7 -2.1 -3.0 -2.9 -2.9 -2.9 -2.7 -3.6 2.9 -3.5 -2.9 -1.6 -0.3 2.2 -2.4 1.4 -0.8 -0.9 -1.6 -1.8 -1.6 -1.5 -1.0 -1.2 -2.6 -1.8 -1.1 -1.8
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.8 0.5 -0.2 -1.4 1.3 0.1 -0.1 -0.4 0.8 1.1 0.2 0.4 -0.0 -0.1 0.6 0.1 0.1 0.7 -0.1 -0.5 0.2 -0.6 -0.3 -1.2 1.3 -0.4 -0.8 0.0 1.7 1.6 0.3 1.5 1.6 1.1 1.4 0.8 0.9 0.2 1.2 1.1 0.4 0.7 0.6 0.9
Hearing difficulty/problems: Yes 1.2 1.9 5.5 -0.1 0.8 -0.1 2.3 1.3 0.6 0.9 1.8 2.0 -1.7 1.6 0.7 0.9 1.1 0.4 1.2 1.7 0.6 -0.7 0.7 0.8 0.7 -1.2 1.2 -1.9 -0.5 2.1 1.3 0.6 1.1 1.2 1.5 2.2 1.1 1.9 1.3 2.1 1.9 1.2 0.7 1.3 -2.3 1.9
Relative age of first facial hair 0.2 0.3 1.4 -0.2 0.4 -0.1 0.8 -0.1 0.4 -0.3 0.7 0.7 0.1 0.7 0.4 0.1 0.6 0.0 0.3 0.7 0.4 0.5 0.5 -0.6 -0.3 0.2 0.6 1.1 -0.0 -0.1 0.6 0.5 0.4 0.4 1.2 0.8 1.1 0.7 0.6 0.5 0.9 0.9 0.7 0.5 -0.0 0.7
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 4.0 0.4 -1.1 -0.5 -0.9 0.2 -0.8 -0.4 -0.9 -0.8 -0.2 -0.9 -0.9 -0.6 -0.9 -0.9 -1.2 -0.9 -0.8 -0.4 -0.4 0.1 -0.4 -1.3 0.1 -2.0 -0.3 0.1 -0.2 -1.1 -0.9 -1.1 -1.3 -0.9 -1.4 -0.9 -1.2 -1.3 -1.1 -1.8 -1.4 -1.5 -0.4 -0.9
Ever used hormone-replacement therapy (HRT) 0.5 0.6 2.9 0.2 -0.0 0.1 1.1 -0.3 0.1 0.6 0.8 1.3 -1.1 0.5 0.1 -0.1 0.9 -0.1 0.2 0.7 0.1 -0.5 -0.2 -0.2 0.7 -0.0 1.3 -0.4 -0.1 0.9 0.8 1.3 0.7 1.7 1.4 1.3 1.1 0.8 0.9 1.1 1.1 1.1 0.4 0.8 -0.0 0.9
Ever had hysterectomy (womb removed) 1.0 1.2 4.1 -1.7 1.1 1.8 -0.6 1.3 1.1 1.5 -0.1 -0.5 0.7 0.3 1.0 1.2 0.6 1.3 1.0 0.2 1.1 1.7 1.0 1.2 1.4 2.0 -1.7 1.1 1.5 0.2 -1.8 -1.4 0.7 -1.2 -0.6 -0.7 -0.3 -0.1 0.1 -0.3 -1.1 -0.3 0.9 0.0 1.6 -0.1
Systolic blood pressure, automated reading 1.8 5.3 19.8 3.5 -2.4 -3.4 0.8 -2.6 -2.5 -2.6 -0.1 1.1 -0.8 -1.2 -2.5 -2.7 -0.9 -2.7 -1.9 -0.6 -2.5 -3.5 -1.8 -3.8 -2.7 -3.6 4.5 -2.6 -3.3 -1.2 2.6 4.2 -1.4 3.3 1.3 1.4 0.3 -0.1 -0.1 0.8 1.5 0.9 -1.7 0.1 -2.4 -0.1
Eye problems/disorders: Diabetes related eye disease 2.5 2.8 8.2 0.5 -1.0 -0.5 -2.3 -1.2 -1.0 -1.0 -2.0 -2.3 -0.0 -1.8 -1.1 -1.1 -2.1 -1.2 -1.3 -1.8 -1.1 -0.1 -0.7 -0.8 -1.1 -0.2 -0.6 0.7 -0.3 -1.8 -1.4 -1.9 -1.7 -2.5 -2.9 -2.4 -2.7 -2.0 -2.2 -2.4 -2.4 -2.6 -1.9 -2.0 -0.8 -2.0
Angina 0.9 1.1 4.4 1.1 -0.8 -1.7 -0.6 -2.1 -1.0 -1.8 -0.7 -0.6 -0.5 -0.9 -1.0 -1.5 -1.2 -1.1 -1.5 -0.8 -1.0 -0.9 -1.2 -1.8 -1.9 -0.9 1.0 0.1 -0.9 -1.4 -1.2 1.2 -1.3 0.6 -0.1 -0.4 -0.7 -0.7 -0.8 -0.0 -0.7 -0.0 -0.4 -0.5 -0.9 -0.7
Medication for hormone replacement therapy 0.3 0.3 1.0 1.0 -0.6 0.6 0.2 -0.7 -0.6 -0.3 -0.0 0.2 -1.0 -0.4 -0.6 -0.7 -0.1 -0.4 -0.7 -0.2 -0.6 -0.7 -0.9 -0.8 -0.3 -1.0 0.9 -0.2 -0.6 -0.1 -0.8 0.7 -0.3 0.5 0.1 0.3 0.0 -0.0 0.1 -0.3 0.5 0.2 -0.7 0.2 -0.0 0.0
Vitamin and mineral supplements 0.4 0.6 1.7 -0.6 0.6 -0.3 0.7 0.7 0.8 0.5 0.7 0.5 0.5 0.7 0.8 0.8 0.6 1.0 1.0 0.8 0.8 0.7 1.3 0.5 0.5 0.5 -1.0 1.3 0.5 1.3 1.3 -0.7 0.6 -0.3 0.6 0.5 0.8 0.7 0.7 0.5 0.9 0.5 0.6 0.4 0.3 0.7
Supplements: Zinc 0.1 0.2 1.7 -0.2 0.0 0.2 0.1 0.7 0.0 0.4 0.1 -0.1 0.7 0.1 0.0 0.4 0.2 0.5 -0.1 0.1 0.0 -0.1 0.1 0.9 0.5 -0.6 -0.0 -1.3 0.2 0.5 -0.0 -0.5 0.1 -0.4 -0.4 -0.0 -0.2 0.1 0.0 -0.5 -0.2 -0.5 -0.2 -0.3 0.5 0.1
Medication: Co-codamol 3.2 3.7 7.9 2.0 -2.0 -1.4 -1.8 -2.4 -2.2 -1.8 -1.9 -1.5 -0.9 -2.0 -2.2 -2.4 -2.1 -2.0 -2.8 -2.0 -2.2 -1.5 -2.2 -1.9 -1.9 -2.0 1.6 -1.4 -1.9 -2.2 -1.9 0.3 -2.2 -0.1 -1.6 -1.3 -2.2 -1.9 -2.2 -1.2 -2.0 -2.2 -2.3 -2.2 -1.6 -1.9
Medication: Metformin 0.3 0.5 4.6 0.1 0.4 -1.6 0.7 -0.0 0.3 0.0 0.7 0.5 2.1 0.3 0.4 0.2 0.6 0.8 -0.2 0.6 0.3 0.3 0.0 0.6 -0.1 -1.1 0.2 -0.8 0.1 0.6 0.1 0.0 0.3 -0.3 0.4 0.6 1.1 0.7 0.7 -0.7 0.8 0.4 0.3 0.3 1.7 0.7
Diabetes (father) 1.8 2.3 5.8 0.8 -1.3 -0.9 -1.6 -1.0 -1.2 -1.1 -1.8 -1.9 0.2 -1.7 -1.3 -1.1 -1.9 -1.3 -2.0 -1.7 -1.3 -0.3 -0.9 -0.0 -1.0 -1.3 -0.4 0.4 -1.0 -1.6 -1.0 -1.4 -1.7 -1.7 -2.1 -1.9 -2.0 -1.8 -2.0 -2.3 -1.9 -2.4 -1.9 -2.2 -0.1 -1.8
Diabetes (mother) 0.1 0.1 0.9 -0.2 0.3 0.8 -0.1 0.6 0.2 0.3 -0.0 -0.0 -0.2 0.1 0.2 0.5 0.0 0.8 0.0 0.1 0.2 0.8 0.4 1.0 0.2 0.4 -0.4 -0.0 0.1 -0.7 -0.6 -0.6 0.1 -0.3 -0.3 -0.1 -0.2 -0.0 -0.2 0.3 -0.3 -0.2 0.1 -0.1 -0.1 -0.0
Severe depression (siblings) 0.4 0.5 3.8 1.0 -0.5 -2.0 0.5 0.2 -0.7 0.1 0.1 0.7 -1.4 -0.1 -0.6 -0.3 -0.3 -0.4 0.0 -0.1 -0.7 -1.1 -0.6 -0.6 0.1 -0.6 1.3 -1.0 -0.6 -0.7 0.0 0.9 -0.3 1.1 0.4 0.6 -0.1 0.0 -0.4 0.5 -0.0 -0.4 -0.7 -0.4 -1.2 0.1
Pack years adult smoking proportion 0.4 0.6 2.6 0.9 -0.3 -0.5 1.1 0.3 -0.3 -0.2 0.6 1.2 -1.3 0.2 -0.3 -0.2 0.3 -0.8 0.7 0.5 -0.3 -1.2 -0.5 -0.6 -0.5 -0.3 1.4 -0.8 -0.4 0.7 0.9 1.6 0.0 1.6 1.0 1.2 0.6 0.7 0.3 1.4 0.7 0.7 0.1 0.5 -1.1 0.7
Impedance of leg (right) 2.5 12.2 22.9 -3.3 4.0 2.3 3.8 3.2 3.8 3.2 4.1 4.0 2.3 3.8 3.7 3.8 4.1 3.0 3.7 4.2 3.9 3.2 3.9 2.6 3.2 3.0 -0.8 1.6 3.0 2.8 2.1 1.0 4.2 1.7 4.0 3.7 4.2 4.1 4.3 4.0 3.4 4.6 4.8 4.5 1.3 4.1
Leg fat-free mass (left) 0.9 4.9 11.0 1.9 -2.4 -1.4 -2.6 -1.6 -2.3 -1.4 -2.7 -2.7 -1.2 -2.4 -2.2 -2.2 -2.7 -1.4 -2.2 -2.7 -2.3 -1.6 -2.2 -1.4 -1.5 -1.7 0.6 -0.2 -1.6 -2.2 -1.2 -1.3 -2.6 -1.8 -3.1 -2.5 -2.9 -2.7 -2.8 -3.0 -2.3 -3.3 -3.2 -3.0 -0.2 -2.7
Trunk fat percentage 0.3 1.1 5.1 -0.9 0.5 1.2 -1.4 0.5 0.4 0.6 -0.9 -1.3 0.0 -0.2 0.4 0.3 -0.3 0.6 -0.5 -0.6 0.5 1.2 0.7 0.8 0.6 1.5 -1.8 1.9 1.5 -0.8 -0.7 -1.9 -0.1 -2.3 -2.0 -1.4 -1.5 -0.8 -0.9 -1.0 -1.4 -1.4 -0.3 -0.5 -0.3 -0.9
Hand grip strength (right) 0.3 0.8 2.0 -0.6 0.7 0.2 1.2 0.1 0.8 0.9 1.1 1.2 -0.4 1.3 0.8 0.4 0.7 1.0 1.0 1.1 0.8 0.0 0.6 0.0 0.9 0.6 0.0 0.2 0.6 1.4 0.7 0.2 1.0 0.6 1.0 1.1 0.9 1.1 1.1 1.3 1.1 1.1 0.9 1.1 -0.5 1.2
Townsend deprivation index at recruitment 2.2 3.0 15.1 2.7 -1.8 -1.2 0.5 -1.7 -2.0 -2.0 -0.3 0.7 -3.3 -0.9 -1.9 -1.9 -0.9 -1.7 -1.1 -0.7 -2.0 -2.6 -2.4 -2.5 -2.2 -2.0 3.0 -1.4 -2.1 -1.1 0.3 3.9 -1.3 3.3 1.4 0.9 0.5 -0.3 -0.3 1.0 0.5 0.9 -0.7 -0.0 -0.4 -0.3
Current tobacco smoking 2.5 4.1 12.4 3.1 -2.6 -3.2 -0.2 -2.0 -2.4 -2.5 -1.0 0.1 -2.1 -1.6 -2.5 -2.4 -1.6 -1.9 -1.4 -1.3 -2.5 -3.1 -2.1 -3.0 -2.6 -2.6 3.4 -2.8 -2.9 -0.5 1.9 3.5 -1.9 2.9 1.0 0.1 0.2 -1.0 -0.8 0.0 -0.0 0.4 -1.3 -0.8 -0.1 -1.0
Average weekly fortified wine intake 0.4 0.5 2.0 0.8 -0.6 -0.8 0.6 -0.4 -0.5 -0.8 0.2 0.5 -0.1 0.1 -0.5 -0.6 0.3 0.4 -0.3 0.1 -0.5 -1.2 -1.0 -0.5 -0.8 -1.0 1.2 -1.3 -0.8 -0.1 -0.5 0.9 -0.4 1.2 0.9 0.6 0.3 0.2 -0.2 0.9 0.1 0.1 -0.0 -0.3 -1.4 0.2
Maternal smoking around birth 0.3 0.5 3.5 -0.4 0.9 1.1 0.5 0.9 0.6 1.1 0.5 0.2 -0.3 0.7 0.7 0.7 0.3 1.0 0.8 0.5 0.6 0.3 0.7 0.6 1.0 1.0 -0.5 1.9 0.4 -0.4 -0.0 -0.3 0.7 -0.1 0.1 0.4 0.6 0.5 0.5 0.1 0.6 0.3 0.4 0.6 1.1 0.5
Fed-up feelings 0.7 1.2 5.6 1.5 -1.3 -1.8 0.3 -1.2 -1.3 -1.4 -0.2 0.3 -0.1 -0.6 -1.2 -1.3 -0.5 -0.1 -0.9 -0.5 -1.3 -1.3 -1.4 -1.9 -1.4 -1.6 2.4 -1.1 -1.4 -1.6 -0.0 2.1 -0.9 1.9 1.0 0.4 0.4 -0.3 -0.2 -0.1 -0.1 0.3 -0.4 -0.4 0.4 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 2.3 0.4 -0.1 -1.5 0.6 -0.5 -0.2 -0.8 0.4 0.4 -0.3 0.2 -0.1 -0.4 0.4 0.2 -0.1 0.3 -0.2 -0.7 -0.1 -0.6 -0.7 -0.7 1.1 0.6 -0.8 -0.5 0.4 1.2 0.0 0.9 0.9 0.6 0.9 0.4 0.5 -0.1 0.7 0.7 0.2 0.3 0.8 0.4
Relative age voice broke 0.5 0.7 3.9 0.6 -0.5 1.0 -0.7 -0.8 -0.8 -1.3 -0.9 -0.9 -2.0 -0.6 -0.7 -0.9 -1.0 -0.6 -0.8 -0.9 -0.7 -0.5 -0.6 -1.2 -1.3 -0.0 0.3 1.0 -0.6 -0.9 -0.5 0.1 -1.0 -0.3 -0.5 -0.8 -0.8 -0.9 -1.0 -0.6 -1.0 -0.8 -0.6 -1.0 -0.6 -0.9
Taking other prescription medications 0.8 1.2 3.3 1.5 -1.3 -1.4 -0.4 -1.6 -1.4 -1.2 -0.7 -0.1 0.3 -1.0 -1.4 -1.6 -0.5 -1.1 -1.6 -0.8 -1.3 -1.2 -1.4 -1.8 -1.1 -1.5 1.7 -1.1 -1.1 -1.2 -0.7 1.8 -1.0 1.3 0.3 -0.1 -0.1 -0.7 -0.6 -0.0 -0.2 -0.1 -0.8 -0.6 0.1 -0.7
Age when periods started (menarche) 0.9 2.2 6.5 1.5 -1.7 -1.8 -1.5 -2.6 -1.6 -1.7 -1.6 -1.4 0.0 -1.8 -1.7 -2.0 -1.5 -1.1 -2.2 -1.7 -1.6 -1.3 -1.7 -1.8 -1.8 -1.1 0.9 -1.0 -1.6 -1.4 -1.5 1.1 -1.6 0.2 -1.0 -1.4 -0.9 -1.6 -1.1 -1.8 -1.0 -0.6 -1.1 -0.9 1.8 -1.6
Bilateral oophorectomy (both ovaries removed) 1.8 2.1 8.6 -1.8 1.1 2.8 -1.4 1.4 0.9 1.3 -0.7 -1.3 -0.7 0.1 0.9 1.1 -0.3 1.5 0.5 -0.4 1.0 2.1 0.7 1.5 1.1 2.2 -2.4 0.6 1.7 -0.5 -2.3 -2.9 0.2 -2.3 -1.9 -1.5 -1.6 -0.7 -1.0 -0.4 -2.3 -1.6 0.3 -0.9 -0.6 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 2.6 6.0 32.7 -3.3 3.1 5.7 0.8 2.9 3.0 2.4 1.6 0.8 0.9 2.4 3.0 3.0 1.8 3.1 2.7 2.0 3.1 3.5 2.5 2.3 2.5 3.9 -3.1 3.3 3.2 1.6 -0.0 -1.9 2.4 -1.2 0.9 0.6 1.6 1.7 1.6 1.1 0.5 1.3 3.0 1.8 1.7 1.6
Tinnitus: Yes, but not now, but have in the past 2.6 2.8 7.3 2.3 -2.0 -1.0 -0.7 -1.7 -2.0 -2.7 -1.2 -0.5 -1.6 -1.7 -2.1 -1.9 -1.7 -2.1 -1.6 -1.4 -2.0 -1.9 -2.1 -2.6 -2.6 -2.1 2.5 -1.4 -2.4 -1.6 -1.0 1.7 -1.9 1.1 -0.3 -0.5 -0.9 -1.2 -1.4 -0.4 -0.7 -0.6 -1.4 -1.1 -1.7 -1.2
Qualifications: CSEs or equivalent 1.4 1.8 4.7 0.9 -1.3 -0.9 -1.8 -1.3 -1.2 -1.2 -1.7 -1.5 0.2 -1.7 -1.3 -1.3 -1.6 -1.6 -1.3 -1.7 -1.2 -0.4 -0.9 -1.4 -1.4 0.3 -0.1 0.3 -0.6 -1.7 -0.9 -0.5 -1.6 -0.9 -1.9 -1.7 -2.2 -1.7 -1.8 -0.8 -1.9 -1.5 -1.4 -1.4 -1.4 -1.8
Serious illness, injury or assault to yourself 0.9 1.1 2.9 -1.5 1.2 0.7 0.2 1.7 1.3 1.4 0.6 0.3 0.9 1.1 1.2 1.5 1.0 1.4 1.3 0.8 1.4 1.6 1.4 1.4 1.3 1.0 -1.2 -0.1 1.5 1.0 -0.0 -1.6 1.1 -1.0 -0.1 0.1 0.4 0.7 0.7 0.4 0.1 0.2 1.0 0.5 0.5 0.6
High blood pressure 0.9 2.4 7.6 2.1 -1.4 -2.8 -0.2 -2.1 -1.7 -2.5 -0.6 -0.3 0.2 -1.2 -1.6 -2.1 -1.2 -1.7 -2.3 -0.9 -1.8 -1.4 -1.2 -2.2 -2.5 -2.6 2.1 -0.6 -2.3 -2.3 -0.1 1.8 -1.4 1.3 0.1 0.1 -0.6 -0.6 -0.8 0.0 0.2 -0.1 -1.3 -0.4 -2.3 -0.6
Hayfever, allergic rhinitis or eczema 0.7 1.5 7.5 1.4 -0.8 -2.7 1.5 -0.7 -0.6 -0.2 0.9 1.5 0.7 0.4 -0.6 -0.7 1.0 -0.8 -0.2 0.7 -0.6 -1.6 -0.4 -1.1 -0.0 -2.5 2.3 -1.6 -1.0 1.0 2.2 1.6 0.2 1.5 1.3 1.6 1.3 0.9 1.0 0.2 2.2 0.9 -0.6 0.6 -0.1 1.0
Multivitamins +/- minerals 0.2 0.3 1.7 0.4 -0.5 1.0 -0.5 -0.3 -0.5 -0.2 -0.5 -0.4 -1.0 -0.4 -0.5 -0.4 -0.2 -0.7 -0.2 -0.5 -0.5 -0.6 -1.3 -0.6 -0.1 -0.3 0.8 -1.0 0.0 -0.1 -0.7 0.5 -0.3 0.3 -0.3 -0.4 -0.3 -0.5 -0.4 -0.6 -0.4 -0.4 -0.5 -0.4 0.1 -0.5
Stomach or abdominal pain in last month 0.5 0.6 2.5 0.1 0.3 -0.7 1.0 0.5 0.2 -0.1 0.9 1.1 -0.2 0.7 0.2 0.4 0.6 1.2 0.6 0.7 0.1 -0.5 -0.2 -0.4 0.1 -0.2 1.0 -0.6 -0.2 0.1 0.6 1.1 0.4 1.3 1.6 1.2 1.4 0.9 0.9 0.6 1.1 1.0 0.7 0.4 0.9 0.9
Supplements: Glucosamine 0.4 0.5 2.0 0.6 -0.8 -0.0 -1.0 -0.8 -0.7 -0.7 -0.8 -0.6 0.1 -0.8 -0.7 -0.9 -0.7 -0.9 -0.8 -0.8 -0.7 -0.4 -0.7 -1.0 -0.6 -0.2 0.0 -0.9 -0.3 -0.4 0.1 0.2 -0.6 0.0 -0.5 -0.8 -0.8 -0.9 -0.8 -0.3 -0.7 -0.5 -0.7 -0.5 -1.4 -0.8
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 1.5 0.0 0.3 0.0 0.6 0.0 0.2 0.3 0.4 0.3 1.2 0.1 0.1 0.1 0.5 0.2 -0.2 0.3 0.2 -0.0 -0.0 0.7 0.6 -0.8 0.5 0.9 -0.1 0.1 -0.6 -0.6 0.3 -0.3 0.1 0.3 0.5 0.4 0.5 -0.6 0.7 0.0 -0.1 0.0 0.8 0.4
Medication: Atenolol 3.2 4.0 7.2 2.2 -2.3 -1.7 -1.9 -2.7 -2.4 -2.4 -2.2 -1.7 -1.0 -2.5 -2.4 -2.6 -2.4 -2.6 -2.6 -2.3 -2.4 -1.8 -2.0 -2.4 -2.4 -2.0 1.3 -2.2 -1.8 -1.8 -0.5 1.5 -2.3 0.9 -1.0 -1.7 -1.6 -2.2 -2.0 -1.6 -1.8 -1.4 -1.9 -1.9 0.0 -2.2
Medication: Levothyroxine sodium 0.2 0.4 1.7 -0.5 0.1 0.2 -0.8 0.1 0.1 0.2 -0.4 -0.7 1.3 -0.4 0.2 -0.0 -0.7 0.7 -0.4 -0.3 0.2 0.2 0.1 0.3 0.4 0.6 -0.8 -0.0 0.4 -0.0 -0.9 -1.2 -0.2 -1.0 -0.7 -0.7 -0.7 -0.4 -0.8 -0.4 -1.2 -1.1 -0.1 -0.9 -0.4 -0.4
Sitting height 1.6 11.1 19.0 -2.5 3.3 0.8 3.9 4.0 3.4 4.3 4.1 3.9 3.2 3.9 3.4 3.8 3.8 3.3 3.5 4.1 3.4 2.8 3.9 3.4 4.4 1.5 0.1 2.1 2.5 2.7 3.2 -0.2 3.9 1.0 3.1 3.8 3.6 4.0 4.0 3.3 3.8 3.5 3.3 3.7 1.2 4.1
Chronic bronchitis/emphysema (father) 2.5 3.0 10.4 -2.2 2.2 1.3 1.0 2.6 2.0 2.6 1.3 1.1 1.0 1.5 2.0 2.2 1.7 0.8 1.9 1.6 2.1 2.1 2.0 2.0 2.6 3.2 -1.8 2.5 2.5 -0.0 0.1 -1.3 1.9 -0.5 0.5 0.7 0.5 1.3 1.2 2.1 0.5 0.9 1.7 1.4 -0.9 1.3
High blood pressure (mother) 0.2 0.3 3.0 0.2 -0.1 -1.7 0.0 0.6 -0.3 -0.3 -0.0 -0.1 0.9 -0.1 -0.2 0.1 -0.2 -1.0 -0.0 -0.1 -0.3 0.1 0.1 0.3 -0.3 -1.1 0.4 -0.9 -0.5 -0.6 -0.3 -0.2 -0.2 0.0 -0.1 0.0 -0.4 -0.1 -0.1 0.2 0.0 -0.3 -0.5 -0.3 -1.3 -0.0
Body mass index (BMI) 1.4 5.9 18.4 0.7 -1.6 -0.1 -3.5 -1.0 -1.6 -1.0 -3.2 -3.6 -1.5 -2.4 -1.6 -1.6 -2.8 -0.9 -2.1 -2.9 -1.6 -0.4 -1.5 -0.7 -1.0 0.1 -1.6 0.6 -0.1 -2.5 -2.0 -2.6 -2.3 -3.4 -4.3 -3.6 -3.7 -3.1 -3.2 -3.6 -3.4 -4.0 -2.8 -3.1 0.1 -3.2
Impedance of leg (left) 3.1 14.9 26.0 -3.3 4.2 2.1 4.4 3.4 4.0 3.5 4.7 4.6 2.4 4.2 3.9 4.0 4.6 3.3 4.2 4.7 4.1 2.9 4.2 2.6 3.6 2.8 -0.5 1.4 2.9 3.6 3.0 1.4 4.5 2.2 4.7 4.4 4.9 4.7 4.8 4.4 4.2 5.1 5.1 4.9 1.4 4.7
Leg predicted mass (left) 1.0 5.2 11.4 2.0 -2.5 -1.5 -2.6 -1.7 -2.4 -1.5 -2.8 -2.7 -1.2 -2.4 -2.3 -2.3 -2.8 -1.4 -2.3 -2.7 -2.4 -1.8 -2.3 -1.5 -1.6 -1.8 0.7 -0.3 -1.7 -2.2 -1.2 -1.2 -2.7 -1.7 -3.1 -2.6 -2.9 -2.7 -2.9 -3.1 -2.4 -3.4 -3.3 -3.1 -0.2 -2.7
Trunk fat mass 0.3 1.4 6.2 -0.3 -0.2 0.6 -1.8 0.2 -0.1 0.3 -1.4 -1.7 -0.2 -0.7 -0.2 -0.2 -1.0 0.3 -0.8 -1.1 -0.1 0.7 0.1 0.4 0.3 0.8 -1.4 1.5 0.9 -1.1 -0.9 -2.0 -0.7 -2.4 -2.5 -1.8 -1.9 -1.3 -1.4 -1.6 -1.7 -2.0 -1.0 -1.2 -0.1 -1.4
Waist circumference 1.1 4.1 14.5 0.1 -1.1 -0.4 -3.1 -0.2 -0.9 -0.5 -2.6 -3.0 -0.1 -1.9 -0.9 -0.8 -2.0 -0.5 -1.6 -2.3 -0.9 0.4 -0.8 0.0 -0.5 0.3 -1.8 0.4 0.1 -1.7 -2.2 -3.0 -1.7 -3.5 -3.8 -3.2 -3.1 -2.5 -2.5 -3.2 -2.8 -3.3 -2.1 -2.5 0.5 -2.6
Number of incorrect matches in round 0.1 0.2 1.6 0.2 0.2 -1.3 0.4 0.7 0.1 0.6 0.3 0.3 0.4 0.3 0.1 0.3 0.4 0.3 0.5 0.3 0.1 0.0 0.6 0.2 0.8 -1.0 0.5 0.5 0.2 0.3 0.6 -0.1 0.4 -0.2 -0.1 0.3 0.3 0.4 0.5 -0.4 0.9 0.1 -0.4 0.5 0.0 0.4
Past tobacco smoking 0.1 0.1 1.0 -0.2 0.2 0.6 0.0 0.6 0.2 0.3 0.1 0.1 0.6 0.2 0.1 0.4 0.2 0.6 0.2 0.1 0.2 0.8 0.4 0.4 0.4 0.3 -0.0 0.2 0.4 -0.2 0.0 -0.0 0.2 -0.3 0.1 -0.0 0.4 0.1 0.2 -0.5 0.1 0.0 0.2 0.0 1.0 0.1
Alcohol usually taken with meals 2.3 3.7 8.8 -2.4 2.5 2.9 1.9 2.0 2.4 2.3 2.0 1.4 0.7 2.3 2.4 2.5 2.0 2.2 1.8 2.2 2.4 2.3 2.1 3.0 2.3 1.9 -1.7 1.5 2.2 1.3 0.1 -1.6 2.2 -0.9 0.6 1.4 1.1 2.0 1.6 1.6 1.1 0.9 1.9 1.6 -0.5 2.0
Nervous feelings 0.8 1.6 3.2 -1.5 1.5 0.9 1.1 1.3 1.4 1.6 1.4 1.2 1.6 1.2 1.4 1.4 1.7 0.9 1.3 1.4 1.4 1.2 1.7 1.0 1.8 0.4 -0.5 0.5 1.5 1.2 1.0 -0.3 1.6 -0.1 1.0 1.0 1.2 1.3 1.6 0.7 1.2 1.2 1.3 1.4 0.9 1.3
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 4.0 1.2 -0.8 -1.7 0.8 -0.9 -0.8 -1.0 0.2 0.7 -1.3 -0.0 -0.8 -0.9 -0.1 -0.8 -0.5 0.0 -0.9 -1.4 -0.6 -1.1 -1.1 -1.8 2.0 -0.8 -1.5 -0.4 0.6 1.5 -0.4 1.4 0.7 0.8 0.3 0.3 0.2 0.4 0.5 0.5 -0.5 0.1 -0.8 0.3
Hearing difficulty/problems with background noise 1.1 1.8 7.1 1.6 -1.4 -2.2 -0.2 -0.7 -1.6 -1.4 -0.8 -0.4 -2.5 -1.1 -1.6 -1.3 -1.4 -1.6 -1.1 -1.0 -1.6 -1.9 -1.1 -0.9 -1.5 -2.7 1.9 -2.5 -1.9 -0.1 -0.1 0.9 -1.4 0.6 -0.3 -0.2 -0.9 -0.8 -0.9 -0.7 -0.5 -0.8 -1.4 -1.1 -1.1 -0.7
Hair/balding pattern: Pattern 2 0.7 1.0 4.1 -0.1 0.4 0.3 1.4 -0.1 0.4 0.3 1.3 1.7 0.2 0.9 0.3 0.1 0.7 0.1 0.8 1.1 0.4 -0.5 0.3 -0.3 0.4 -0.3 1.2 -0.3 -0.1 0.8 2.0 1.2 0.9 1.5 1.5 1.6 1.2 1.3 1.2 1.4 1.3 1.3 0.8 1.1 -0.5 1.3
Had menopause 0.3 0.4 1.8 -0.3 0.3 0.4 0.8 1.3 0.4 1.0 0.7 0.8 0.8 0.4 0.4 0.8 0.8 0.4 0.5 0.6 0.4 0.3 0.5 1.1 1.0 -0.2 0.8 -0.4 0.3 1.0 0.5 0.1 0.8 0.1 0.4 0.7 0.7 0.7 0.8 -0.1 0.7 0.4 0.2 0.6 0.9 0.7
Had other major operations 1.5 1.9 3.7 1.5 -1.7 -1.5 -1.1 -1.4 -1.7 -1.6 -1.3 -1.0 -1.1 -1.6 -1.6 -1.5 -1.5 -1.9 -1.9 -1.4 -1.7 -1.4 -1.5 -1.3 -1.6 -1.9 1.1 -1.5 -1.3 -1.3 -1.0 0.9 -1.5 0.5 -0.9 -0.9 -1.3 -1.3 -1.3 -0.8 -1.0 -1.0 -1.5 -1.2 -0.9 -1.3
Forced vital capacity (FVC) 0.4 1.5 3.0 -0.9 1.0 -0.1 1.7 1.5 1.1 1.7 1.6 1.7 1.7 1.5 1.0 1.4 1.0 1.0 1.0 1.5 1.1 1.3 1.6 1.4 1.6 0.2 0.2 0.7 0.5 0.1 1.0 0.2 1.4 0.6 1.2 1.5 1.4 1.5 1.6 0.9 1.2 1.4 1.2 1.4 1.1 1.6
Heel bone mineral density (BMD) T-score, automated (right) 4.3 9.9 42.8 -3.8 3.8 6.5 1.7 3.6 3.8 3.2 2.5 1.7 0.8 3.1 3.8 3.9 2.7 3.6 3.9 2.9 3.9 3.9 3.4 2.9 3.3 4.6 -3.5 3.4 3.9 3.2 1.6 -1.7 3.3 -1.0 1.7 1.5 2.5 2.5 2.5 1.9 1.4 2.3 4.0 2.8 2.3 2.5
Ever unenthusiastic/disinterested for a whole week 0.1 0.2 2.5 -0.4 0.2 0.9 0.2 0.8 0.2 0.2 0.2 0.2 0.8 0.1 0.2 0.5 0.4 -0.0 0.1 0.2 0.2 0.3 -0.2 0.4 0.2 -0.4 0.3 -0.9 0.6 0.3 -1.6 0.0 0.3 -0.3 -0.1 0.1 -0.1 0.2 0.1 -0.2 -0.2 -0.1 -0.0 0.0 -0.1 0.2
Qualifications: None of the above 0.1 0.2 2.2 -0.1 0.0 -1.1 0.3 -0.3 0.1 -0.1 0.3 0.4 -0.6 -0.1 0.0 -0.1 0.2 -0.4 -0.1 0.3 0.1 -0.1 0.4 0.0 -0.2 -0.3 0.3 -1.5 0.4 0.7 1.1 0.6 0.2 0.1 0.0 0.4 0.1 0.3 0.3 0.3 0.1 0.3 0.3 0.3 -0.2 0.3
Financial difficulties in last 2 years 0.1 0.2 0.7 -0.5 0.3 -0.6 0.4 0.7 0.4 0.5 0.3 0.2 0.4 0.2 0.4 0.4 0.6 0.2 0.1 0.3 0.4 0.8 0.5 0.5 0.4 -0.7 -0.2 0.5 0.2 0.4 -0.9 -0.8 0.2 -0.5 -0.0 0.1 0.0 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.3
Mouth/teeth dental problems 0.5 0.8 3.0 -0.8 1.0 1.1 0.5 1.3 1.0 1.0 0.6 0.3 0.8 0.7 1.0 1.1 0.7 -0.1 1.4 0.7 1.0 1.1 1.5 0.8 0.9 1.1 -0.9 1.6 0.8 1.1 1.7 -0.8 0.8 -0.6 -0.0 0.3 0.2 0.6 0.7 0.7 0.7 0.6 0.6 1.0 -0.6 0.6
Heart attack 0.5 0.6 2.3 0.9 -0.5 -1.5 -0.2 -1.2 -0.7 -1.2 -0.3 -0.0 -0.8 -0.6 -0.6 -0.8 -0.6 -0.5 -0.4 -0.5 -0.6 -0.8 -0.9 -1.4 -1.4 -0.1 0.8 0.6 -0.8 -1.0 -1.2 1.5 -0.7 1.4 0.6 0.1 0.1 -0.4 -0.5 0.9 -0.2 0.4 0.1 -0.1 -0.1 -0.3
Allergy 0.6 1.4 8.6 -1.0 0.4 1.4 -1.5 0.8 0.3 0.2 -1.1 -1.6 -0.3 -0.6 0.2 0.6 -1.0 0.4 0.0 -0.8 0.3 1.2 0.1 1.1 0.2 1.9 -2.1 1.1 0.7 -0.8 -2.9 -1.7 -0.4 -1.7 -1.5 -1.7 -1.5 -1.1 -1.2 -0.6 -2.1 -1.3 0.0 -1.0 0.1 -1.1
Pain all over the body in last month 0.9 1.0 2.1 0.7 -0.9 -0.4 -1.0 -0.7 -0.9 -0.9 -1.1 -1.1 -1.0 -0.9 -0.9 -1.0 -1.1 -0.8 -1.3 -1.1 -1.0 -0.3 -1.1 -0.6 -1.0 -1.0 0.1 -0.5 -0.8 -1.1 -1.3 -0.5 -1.2 -0.8 -1.4 -1.0 -1.5 -1.1 -1.4 -0.7 -1.4 -1.4 -1.1 -1.4 -0.4 -1.1
Diabetes (self-reported) 0.4 0.5 1.5 -0.2 0.7 -0.6 1.2 0.8 0.6 0.3 1.1 1.0 0.7 0.9 0.7 0.7 0.9 0.7 0.3 1.1 0.6 0.4 0.3 1.0 0.1 -0.6 0.3 0.1 0.3 1.0 -0.3 -0.1 0.6 -0.1 0.7 1.1 1.1 1.1 0.9 0.2 1.1 0.6 0.6 0.6 0.7 1.2
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 3.5 0.1 0.1 -0.3 0.4 0.9 0.2 0.6 0.4 0.5 1.9 0.4 0.2 0.5 0.7 0.2 0.3 0.4 0.3 0.2 0.1 0.4 0.7 -0.1 0.3 0.1 0.5 0.2 0.4 -0.3 0.2 -0.2 0.3 0.4 0.3 0.4 0.1 0.4 0.5 -0.2 -0.1 -0.0 -0.5 0.4
Medication: Ramipril 0.4 0.5 3.8 0.7 -0.0 0.4 1.0 -0.2 -0.2 -0.3 0.7 1.1 -0.8 0.3 -0.2 -0.2 0.3 -0.4 -0.0 0.5 -0.3 -0.6 -0.2 -0.6 -0.3 -1.1 1.3 -0.4 -1.0 0.1 -0.3 1.0 0.1 1.3 1.0 1.1 0.5 0.7 0.3 1.2 0.9 0.6 0.0 0.5 -1.9 0.7
Medication: Simvastatin 1.2 1.7 4.2 -0.7 1.3 -0.5 1.7 0.8 1.2 1.0 1.7 1.7 2.0 1.2 1.2 1.0 1.4 0.8 0.7 1.6 1.1 1.0 1.6 1.1 1.0 0.3 0.0 -0.2 0.8 1.0 1.6 0.5 1.6 0.8 1.5 1.7 2.0 1.7 1.8 0.9 1.9 1.7 1.4 1.7 1.1 1.7
Fluid intelligence score 0.4 0.8 2.6 -0.0 0.4 -1.1 1.6 0.1 0.4 0.5 1.3 1.6 0.5 0.8 0.4 0.2 1.1 -0.1 0.2 1.1 0.4 0.2 0.3 -0.1 0.5 -0.6 1.1 -0.1 -0.3 0.1 1.1 0.7 0.7 1.3 1.5 1.6 1.2 1.2 1.0 1.5 1.4 1.2 0.7 0.9 -0.5 1.3
Illnesses of siblings 1.3 1.8 5.3 -0.2 0.7 1.6 2.0 0.6 0.8 1.2 1.7 2.0 -0.0 1.5 0.8 0.7 1.5 0.7 1.2 1.6 0.7 -0.3 0.4 0.3 1.3 -0.2 0.9 0.1 0.1 1.9 2.3 1.1 1.3 1.8 2.2 2.1 1.9 1.7 1.6 1.8 2.0 1.6 1.1 1.4 -0.3 1.8
Neuroticism score 0.3 0.6 3.5 0.9 -0.8 -0.4 0.4 -0.6 -0.8 -0.7 0.1 0.5 0.2 -0.5 -0.8 -0.8 0.1 -0.3 -0.4 -0.2 -0.8 -1.1 -0.6 -1.4 -0.6 -1.6 1.9 -1.6 -1.0 -0.4 0.2 1.5 -0.3 1.2 0.6 0.5 0.2 0.0 0.2 0.0 0.4 0.4 -0.5 0.0 -0.6 0.1
Weight 0.7 3.5 12.1 0.7 -1.4 -0.7 -2.7 -0.5 -1.3 -0.4 -2.4 -2.7 -0.7 -1.8 -1.3 -1.1 -2.2 -0.5 -1.6 -2.2 -1.3 -0.4 -1.1 -0.3 -0.4 -0.3 -0.8 0.5 -0.2 -1.8 -1.3 -2.2 -1.8 -2.8 -3.5 -2.7 -2.9 -2.4 -2.4 -3.1 -2.5 -3.2 -2.4 -2.4 0.5 -2.4
Impedance of arm (right) 1.1 5.1 14.3 -1.1 1.8 1.1 3.0 0.7 1.8 1.1 2.9 3.2 0.5 2.5 1.8 1.4 2.8 1.0 1.5 2.7 1.8 1.1 1.9 0.7 0.9 0.8 1.0 0.3 0.7 1.7 1.9 2.4 2.4 2.8 3.5 3.2 3.0 2.9 2.9 3.8 2.9 3.7 2.9 3.3 -1.0 2.9
Arm fat percentage (right) 0.6 2.3 8.2 0.2 -0.7 0.5 -2.3 -0.6 -0.7 -0.4 -1.9 -2.2 -1.1 -1.3 -0.8 -0.9 -1.5 -0.5 -1.5 -1.7 -0.7 0.2 -0.6 -0.2 -0.4 0.7 -1.4 0.8 0.3 -1.6 -1.1 -1.8 -1.3 -2.4 -2.9 -2.3 -2.5 -1.9 -2.0 -1.9 -2.2 -2.4 -1.6 -1.7 -0.6 -2.0
Trunk fat-free mass 0.8 4.5 11.0 1.9 -2.4 -2.1 -2.4 -1.0 -2.2 -1.1 -2.5 -2.5 -0.7 -2.4 -2.2 -1.8 -2.7 -1.2 -1.6 -2.5 -2.2 -1.7 -2.1 -1.1 -1.2 -1.8 0.6 -0.5 -1.8 -1.8 -1.0 -1.4 -2.5 -1.8 -3.0 -2.5 -2.7 -2.5 -2.5 -3.3 -2.2 -3.2 -3.1 -2.9 0.8 -2.5
Hip circumference 0.5 2.3 6.8 0.8 -1.4 -0.6 -2.2 -0.5 -1.3 -0.7 -2.0 -2.1 -1.0 -1.5 -1.3 -1.1 -1.7 -0.3 -1.4 -1.9 -1.3 -0.6 -1.0 -0.7 -0.5 -0.1 -0.4 0.3 -0.4 -1.8 -0.2 -1.2 -1.5 -1.8 -2.6 -2.1 -2.1 -2.0 -1.9 -2.5 -1.9 -2.5 -2.0 -1.9 0.6 -2.0
Time employed in main current job 0.3 0.4 3.1 0.1 0.1 0.7 0.6 -0.2 0.1 0.4 0.4 0.8 -1.8 0.2 0.0 0.0 0.3 -0.4 0.4 0.3 0.1 -0.3 0.3 0.0 0.2 0.7 0.0 -0.7 -0.0 0.7 1.5 0.9 0.4 1.3 0.9 0.6 0.7 0.4 0.5 1.0 0.5 0.9 0.5 0.6 -0.2 0.4
Alcohol intake versus 10 years previously 0.5 0.8 3.6 -0.1 -0.2 0.2 -1.4 0.0 -0.4 -0.1 -1.2 -1.4 -0.5 -0.8 -0.3 -0.3 -0.6 0.1 -0.9 -1.0 -0.3 0.6 -0.4 -0.1 0.1 -0.2 -0.9 0.3 0.5 -1.4 -1.7 -0.5 -0.6 -1.0 -1.3 -1.5 -0.9 -1.1 -0.7 -1.6 -1.3 -0.8 -0.4 -0.7 1.9 -1.2
Father’s age at death 0.7 1.0 7.3 -1.0 0.5 0.8 -0.9 0.8 0.6 0.9 -0.5 -1.0 0.7 -0.2 0.6 0.8 0.2 0.4 0.2 -0.2 0.6 1.2 0.4 1.5 0.8 0.4 -2.0 -0.3 1.5 0.8 -0.3 -1.5 0.3 -2.0 -1.5 -1.1 -0.4 -0.4 0.1 -2.0 -0.4 -0.5 0.0 0.1 2.7 -0.4
Worrier / anxious feelings 0.2 0.5 1.2 -0.1 0.1 0.4 1.0 0.8 0.2 0.4 0.8 1.1 1.1 0.5 0.2 0.5 1.0 -0.1 0.6 0.7 0.2 0.0 0.7 -0.1 0.4 -0.4 0.9 -0.7 0.1 0.6 -0.3 0.7 0.6 0.8 0.8 1.0 0.5 0.8 0.8 1.1 0.9 0.8 0.3 0.7 -1.1 0.9
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 2.8 -1.1 1.1 -0.4 0.5 1.7 1.0 1.1 0.6 0.2 0.5 1.0 1.1 1.2 0.8 1.0 0.8 0.8 1.0 1.4 0.9 1.6 1.1 0.1 -0.4 1.0 0.9 0.2 -1.2 -1.4 0.8 -0.9 -0.2 0.2 0.0 0.6 0.4 0.2 -0.0 -0.2 0.5 0.3 -0.4 0.6
Falls in the last year 1.3 1.8 6.4 1.9 -1.8 -1.5 -0.0 -1.0 -1.7 -1.8 -0.5 0.3 -0.6 -1.1 -1.8 -1.6 -0.9 -1.3 -1.0 -0.8 -1.7 -1.9 -1.7 -2.1 -1.6 -1.5 2.3 -2.5 -1.9 -0.8 0.0 2.3 -1.2 2.2 1.3 0.3 0.4 -0.5 -0.6 0.2 -0.2 0.0 -0.8 -1.0 -0.1 -0.5
Hair/balding pattern: Pattern 3 1.0 1.5 4.4 0.4 -0.6 0.4 -1.6 -0.7 -0.7 -1.0 -1.5 -1.7 -2.1 -0.9 -0.7 -0.7 -1.5 -0.5 -0.9 -1.4 -0.7 -0.1 -0.6 -0.6 -0.9 0.1 -0.7 1.4 -0.3 -1.0 -1.6 -1.3 -1.4 -1.6 -1.5 -1.7 -1.5 -1.5 -1.7 -1.6 -1.8 -1.8 -1.1 -1.7 -0.3 -1.5
Number of live births 0.7 1.0 4.9 -0.9 0.4 0.3 -1.5 -0.0 0.4 0.0 -0.9 -1.5 0.7 -0.5 0.3 0.1 -0.3 0.4 -0.4 -0.7 0.4 1.1 0.9 1.4 0.2 1.3 -1.6 1.5 1.3 -0.7 -0.6 -1.6 -0.0 -2.2 -1.8 -1.6 -0.9 -0.9 -0.5 -1.4 -0.9 -0.9 -0.2 -0.4 1.0 -0.9
Forced expiratory volume in 1-second (FEV1) 0.2 0.5 1.2 -0.5 0.5 -0.6 1.0 0.5 0.6 0.9 1.0 1.0 1.1 0.9 0.5 0.6 0.6 0.5 0.6 0.9 0.6 0.8 0.8 0.8 0.8 -0.3 0.3 0.4 0.1 0.0 0.3 0.1 0.8 0.2 0.7 0.9 0.8 0.9 1.1 0.3 0.8 1.0 0.7 0.9 1.0 1.0
Pulse rate 0.1 0.2 1.2 0.5 -0.5 0.1 -0.4 0.9 -0.5 -0.2 -0.6 -0.4 0.5 -0.8 -0.5 0.0 -0.3 -0.3 0.3 -0.6 -0.4 -0.3 -0.7 -0.4 -0.4 0.2 0.2 -0.1 -0.5 -0.9 -0.4 -0.2 -0.5 -0.0 -0.5 -0.5 -0.3 -0.6 -0.6 -0.4 -0.4 -0.6 -0.5 -0.6 1.1 -0.6
Happiness 0.5 0.6 5.8 -0.6 0.6 0.6 0.6 1.3 0.8 1.2 0.7 0.6 2.4 0.5 0.8 1.1 0.7 0.4 1.0 0.8 0.8 1.1 0.7 0.5 1.3 0.4 -0.6 0.5 0.7 0.7 -0.5 -0.7 0.7 -0.5 0.1 0.5 0.2 0.7 0.5 0.3 0.5 0.2 0.3 0.6 -0.3 0.7
Noisy workplace 4.5 5.6 8.6 2.5 -2.8 -0.5 -2.4 -2.1 -2.8 -2.7 -2.7 -2.1 -1.9 -2.8 -2.8 -2.7 -2.9 -2.5 -2.5 -2.8 -2.8 -2.2 -2.9 -2.3 -2.6 -1.9 1.2 -2.0 -2.4 -2.4 -1.1 0.7 -2.8 0.2 -1.7 -2.1 -2.5 -2.7 -2.9 -1.6 -2.4 -2.5 -2.9 -2.8 -1.9 -2.7
Qualifications: A levels/AS levels or equivalent 0.2 0.4 2.0 -0.2 0.4 -0.3 0.6 -0.7 0.3 0.3 0.6 0.5 1.4 0.8 0.3 0.2 0.9 0.8 0.1 0.6 0.3 -0.1 -0.2 -0.1 0.5 -0.6 0.2 0.4 -0.1 0.6 -0.7 0.5 0.6 0.7 1.0 0.7 1.2 0.6 0.9 -0.0 1.2 0.8 0.4 0.6 1.4 0.6
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 5.8 0.1 -0.4 0.3 -0.4 -0.2 -0.3 -0.7 -0.3 -0.2 -0.1 -0.5 -0.3 -0.2 -0.4 -1.1 0.3 -0.4 -0.3 -0.0 -0.3 -0.8 -0.6 0.1 0.1 -1.3 -0.7 -0.5 0.1 -0.5 -0.4 0.2 -0.1 -0.2 -0.8 -0.3 -1.0 0.9 -1.0 -0.8 -0.3 -0.8 -2.4 -0.3
Mouth/teeth dental problems: Dentures 1.1 1.8 3.6 1.3 -1.6 -0.1 -1.4 -1.5 -1.6 -1.5 -1.5 -1.2 -0.9 -1.5 -1.6 -1.7 -1.7 -0.8 -1.8 -1.6 -1.6 -1.2 -1.7 -1.2 -1.4 -1.1 0.8 -1.2 -1.1 -1.5 -1.0 0.2 -1.6 -0.1 -1.1 -1.2 -1.1 -1.5 -1.6 -1.5 -1.5 -1.6 -1.6 -1.9 0.3 -1.5
Asthma 0.2 0.4 1.6 0.5 -0.1 0.2 0.6 -0.9 -0.2 -0.5 0.5 0.7 0.0 0.2 -0.1 -0.5 0.3 0.2 -0.3 0.3 -0.2 -0.4 -0.4 -1.2 -0.7 -0.8 1.0 -0.3 -0.5 -0.1 1.3 1.1 0.1 1.0 0.8 0.9 0.6 0.5 0.4 0.7 0.8 0.8 0.3 0.6 -0.2 0.5
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 3.4 1.2 -1.4 -1.8 -0.6 -1.4 -1.2 -1.3 -0.8 -0.7 -0.5 -1.2 -1.1 -1.3 -0.7 -0.7 -1.0 -1.0 -1.3 -1.4 -1.3 -1.3 -1.4 -1.8 1.6 -1.2 -1.2 -0.5 -0.1 0.9 -1.0 0.3 -0.4 -0.5 -0.3 -0.9 -0.5 -1.6 -0.1 -0.5 -1.2 -0.7 0.9 -0.8
Medication: Cholesterol lowering 1.8 2.7 4.9 -1.5 1.9 -0.4 2.0 1.2 1.9 1.5 2.2 2.0 0.7 1.8 1.9 1.7 1.6 1.4 1.7 2.2 1.8 1.5 2.1 1.2 1.3 1.0 -0.6 0.4 1.1 1.7 1.5 0.2 2.0 0.6 1.6 2.0 1.8 2.1 1.9 2.1 1.8 1.9 2.2 2.2 -0.2 2.1
Depression (self-reported) 0.5 0.6 2.3 -1.0 0.9 0.5 0.5 0.9 0.9 0.8 0.6 0.2 1.4 0.7 0.9 0.9 0.7 1.5 0.9 0.7 0.8 0.8 1.2 0.8 1.0 0.1 -0.4 0.6 1.2 0.3 0.5 -0.6 0.8 -0.6 0.5 0.3 0.9 0.6 0.7 -0.5 0.5 0.1 0.6 0.2 1.3 0.6
Medication: Lansoprazole 2.8 3.1 10.0 2.5 -2.0 -0.5 0.4 -2.2 -2.1 -1.9 -0.5 0.8 -2.5 -1.0 -2.2 -2.3 -0.9 -2.2 -2.0 -0.8 -2.1 -2.7 -2.2 -2.2 -1.9 -2.9 3.2 -2.8 -2.9 -0.5 1.0 2.7 -1.3 2.7 1.0 0.7 0.1 -0.5 -0.6 0.5 0.2 -0.1 -1.3 -0.8 -0.9 -0.4
Prospective memory result 0.9 1.1 4.1 0.1 -0.3 1.1 -1.7 0.4 -0.5 -0.5 -1.5 -1.8 -0.1 -1.1 -0.5 -0.1 -1.1 -0.4 -0.2 -1.3 -0.5 0.4 -0.1 0.3 -0.4 0.3 -1.2 1.0 0.0 -0.8 -1.2 -0.8 -0.6 -1.3 -1.7 -1.9 -1.1 -1.5 -1.0 -2.0 -1.1 -1.2 -0.9 -0.8 1.4 -1.5
Lung cancer (father) 0.3 0.4 2.1 -0.1 -0.2 0.2 -0.6 0.5 -0.3 -0.3 -0.7 -0.8 0.3 -0.5 -0.2 0.0 -0.4 0.2 -0.5 -0.6 -0.3 0.2 -0.3 -0.1 -0.2 -0.0 -0.2 0.3 -0.4 -1.0 -1.5 -1.0 -0.5 -0.9 -0.7 -0.8 -0.7 -0.6 -0.8 -0.7 -0.8 -1.1 -0.6 -1.1 -0.1 -0.6
Illnesses of mother 1.2 1.5 4.9 -1.2 1.1 2.2 1.0 1.0 1.3 1.4 1.2 1.1 1.0 1.5 1.3 1.3 1.5 1.2 1.3 1.3 1.3 0.7 1.0 1.0 1.3 1.4 -0.9 0.3 1.7 1.9 1.7 -0.1 1.4 0.0 0.8 1.0 1.2 1.2 1.2 0.9 1.1 1.0 1.3 1.3 0.4 1.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.4 1.3 -0.2 0.3 -0.3 1.1 0.7 0.5 0.5 0.9 1.0 0.9 0.8 0.4 0.6 0.7 0.2 0.6 0.8 0.4 0.6 0.5 0.9 0.6 -0.3 0.4 0.5 0.1 0.2 0.4 0.1 0.7 0.3 0.8 0.9 1.0 0.8 1.0 0.2 1.1 0.8 0.4 0.7 0.7 0.9
Pulse wave Arterial Stiffness index 0.8 1.0 5.5 0.1 -0.4 -0.4 -1.3 -0.0 -0.4 -0.6 -1.2 -1.6 0.9 -1.3 -0.5 -0.2 -0.8 -0.7 -0.6 -1.1 -0.4 0.3 -0.3 0.3 -0.6 0.6 -0.8 0.3 -0.7 -0.9 -1.0 -1.0 -0.8 -1.3 -1.3 -1.5 -0.6 -1.2 -0.7 -2.3 -1.0 -0.9 -0.6 -0.9 2.3 -1.3
Impedance of arm (left) 1.6 7.5 16.8 -2.0 2.6 2.0 3.3 1.7 2.7 1.9 3.4 3.5 1.1 3.1 2.6 2.4 3.5 1.8 2.4 3.3 2.7 2.0 2.7 1.7 1.9 1.6 0.2 1.2 1.8 2.3 2.0 1.8 3.2 2.3 3.7 3.4 3.5 3.4 3.5 4.0 3.2 4.1 3.6 3.8 -0.4 3.4
Arm fat mass (right) 0.5 2.1 8.7 0.3 -0.8 0.0 -2.1 -0.3 -0.7 -0.1 -1.8 -2.1 -0.8 -1.2 -0.7 -0.7 -1.5 -0.2 -1.2 -1.6 -0.7 0.0 -0.6 -0.1 -0.1 0.4 -1.2 0.6 0.3 -1.4 -0.7 -1.9 -1.2 -2.5 -3.0 -2.2 -2.4 -1.8 -1.8 -2.3 -2.0 -2.5 -1.7 -1.7 0.2 -1.8
Trunk predicted mass 0.8 4.7 10.9 2.0 -2.5 -2.1 -2.4 -1.0 -2.3 -1.2 -2.6 -2.5 -0.8 -2.4 -2.2 -1.9 -2.8 -1.3 -1.7 -2.6 -2.3 -1.8 -2.1 -1.2 -1.3 -1.9 0.7 -0.6 -1.9 -1.9 -0.9 -1.3 -2.5 -1.8 -3.0 -2.4 -2.7 -2.6 -2.6 -3.3 -2.2 -3.1 -3.1 -2.9 0.8 -2.6
Standing height 0.1 1.4 3.4 0.1 0.3 -1.5 1.6 1.1 0.6 1.3 1.4 1.8 1.5 1.0 0.5 0.9 1.1 0.8 1.2 1.3 0.5 -0.2 0.8 0.7 1.2 -0.8 1.6 -0.2 -0.3 1.4 1.8 0.7 1.0 1.0 1.3 1.7 1.5 1.4 1.6 0.9 1.8 1.5 0.6 1.3 0.9 1.5
Length of working week for main job 0.3 0.3 2.6 0.7 -0.3 -0.4 0.3 -0.8 -0.5 0.3 0.1 0.5 -1.6 -0.1 -0.4 -0.7 -0.1 -0.7 -0.3 0.0 -0.4 -1.0 -0.3 -0.9 0.1 -0.3 0.7 0.3 -0.5 -0.1 0.7 0.9 -0.2 1.1 0.6 0.5 0.1 0.1 -0.0 0.8 0.4 0.1 -0.5 -0.0 -1.0 0.2
Exposure to tobacco smoke at home 0.2 0.2 2.8 0.2 0.1 0.5 0.1 0.5 -0.1 0.4 -0.0 -0.0 -1.7 -0.1 -0.1 0.1 0.1 0.2 0.4 -0.0 -0.1 -0.5 -0.4 0.1 0.4 -0.5 0.0 0.6 -0.1 0.5 -0.8 0.2 -0.1 0.2 0.1 0.0 0.3 0.0 0.1 -0.6 0.2 -0.1 -0.1 -0.1 1.4 -0.1
Breastfed as a baby 0.4 0.4 2.0 0.8 -0.9 -0.5 0.3 -0.4 -0.7 -0.9 -0.0 0.4 -1.2 -0.2 -0.8 -0.6 -0.4 -0.4 -0.4 -0.2 -0.8 -1.4 -1.0 -0.1 -0.9 -1.4 1.1 -0.8 -1.3 0.2 0.1 0.9 -0.6 0.8 0.3 0.4 0.0 -0.1 -0.1 0.0 -0.1 0.1 -0.3 -0.3 -0.1 -0.0
Tense / ‘highly strung’ 0.1 0.2 0.7 -0.7 0.4 0.4 -0.3 0.4 0.3 0.6 -0.1 -0.2 0.3 0.0 0.3 0.5 0.2 0.7 0.6 -0.0 0.3 0.6 0.5 0.2 0.7 0.4 -0.5 0.1 0.8 -0.3 -0.5 -0.6 0.4 -0.7 -0.4 -0.3 -0.4 -0.1 -0.0 -0.6 -0.2 -0.5 -0.1 -0.0 -0.4 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 2.2 -0.0 -0.3 -0.0 -0.4 0.3 -0.3 -0.3 -0.6 -0.6 1.1 -0.3 -0.3 -0.1 -0.4 0.1 -0.1 -0.6 -0.3 -0.3 -0.3 -0.1 -0.1 -0.5 0.5 -0.6 0.4 -0.5 -1.5 -0.5 -0.4 -1.0 -0.9 -0.6 -1.0 -0.6 -0.6 -0.9 -0.8 -1.0 -0.8 -0.7 -0.8 -0.6
Hair/balding pattern: Pattern 4 0.7 1.7 5.2 0.1 -0.6 1.0 -1.9 -0.6 -0.6 0.1 -1.7 -2.0 0.5 -1.3 -0.6 -0.5 -1.0 -0.6 -1.2 -1.5 -0.6 0.3 -0.8 0.6 0.1 -0.1 -1.2 -0.4 -0.1 -1.2 -1.8 -1.8 -1.0 -1.9 -2.3 -2.1 -1.8 -1.7 -1.6 -2.3 -1.9 -2.1 -1.5 -1.6 0.4 -1.7
Birth weight of first child 0.6 1.1 5.6 -1.3 0.9 2.4 0.5 1.0 1.2 1.4 0.7 0.5 1.2 1.1 1.1 1.1 1.0 1.0 1.2 0.8 1.2 0.7 1.1 1.3 1.2 1.3 -1.4 0.1 1.4 2.0 0.4 -1.3 1.1 -1.2 -0.2 0.3 0.3 0.7 0.7 0.1 0.5 0.1 0.6 0.6 0.2 0.7
Peak expiratory flow (PEF) 0.0 0.1 0.6 -0.3 -0.0 -0.1 -0.2 -0.7 0.2 0.1 -0.0 -0.2 0.0 0.1 0.1 -0.2 -0.2 0.3 -0.3 0.0 0.1 0.4 -0.0 0.0 0.1 -0.2 -0.3 0.2 0.2 0.1 -0.1 -0.5 -0.0 -0.5 -0.2 -0.2 -0.2 -0.0 -0.0 -0.4 -0.2 -0.2 0.0 -0.2 0.2 -0.0
Pulse wave reflection index 0.6 0.7 2.9 -1.1 0.9 1.7 -0.1 0.9 0.8 0.7 0.1 -0.6 0.5 0.3 0.8 0.8 0.4 0.6 0.0 0.2 0.7 1.3 1.1 1.6 0.8 0.7 -1.4 1.5 0.5 0.3 -0.0 -1.6 0.5 -1.6 -0.5 -0.4 0.0 0.1 0.3 -1.6 0.0 -0.3 0.2 0.1 1.4 0.1
Ever highly irritable/argumentative for 2 days 0.8 0.9 3.2 -0.3 0.4 -0.6 1.3 0.4 0.5 0.2 1.1 1.4 -0.1 0.8 0.5 0.5 1.1 1.3 0.9 1.0 0.5 0.1 0.2 -0.1 0.1 0.4 0.3 -0.6 0.6 0.5 -0.3 1.5 0.8 1.7 1.8 1.3 1.4 1.1 1.2 1.7 1.0 1.7 1.2 1.1 0.4 1.1
Loud music exposure frequency 0.5 0.6 3.8 1.1 -0.8 -0.4 0.3 -0.3 -0.8 -0.3 -0.0 0.4 -1.6 -0.1 -0.8 -0.5 -0.3 -0.6 -0.5 -0.2 -0.8 -1.3 -1.3 -0.4 -0.3 -1.5 1.3 -1.9 -0.8 0.3 -0.5 0.8 -0.3 0.7 0.1 0.5 -0.1 0.0 -0.1 -0.2 0.4 -0.3 -1.0 -0.2 -0.8 0.0
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 2.0 0.5 -0.2 -0.4 0.6 -0.8 -0.2 -0.1 0.3 0.8 1.3 0.2 -0.3 -0.5 0.3 -0.5 -0.3 0.2 -0.2 -0.5 -0.4 -1.0 0.1 -0.2 0.9 0.0 -0.2 -0.3 0.2 0.9 0.0 1.2 1.4 0.7 1.1 0.3 0.2 0.6 0.6 0.5 0.1 -0.1 0.4 0.3
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.7 -0.3 0.2 -1.2 0.8 0.5 0.3 0.2 0.7 0.8 -0.4 0.5 0.3 0.5 0.5 0.5 0.6 0.7 0.3 -0.4 0.1 0.0 0.3 -0.2 0.4 -1.3 -0.4 0.9 0.0 0.8 0.6 1.1 1.1 0.8 1.0 0.8 0.9 0.7 0.8 1.1 0.9 0.7 0.9 0.7
Blood clot in the leg (DVT) 0.4 0.5 1.6 -0.0 -0.2 0.3 -1.1 -0.8 -0.3 -0.1 -1.0 -1.2 0.5 -1.0 -0.2 -0.5 -0.7 -0.9 -0.6 -0.8 -0.2 0.3 -0.1 -0.5 -0.3 0.6 -0.5 1.1 0.0 -1.1 -0.6 -0.4 -0.4 -0.8 -1.1 -1.2 -0.9 -1.0 -0.4 -1.0 -0.9 -0.3 -0.4 -0.2 0.9 -1.0
Medication: Paracetamol 0.4 0.6 1.9 0.1 0.4 0.6 1.3 0.7 0.3 0.3 1.1 1.1 0.5 0.6 0.3 0.4 1.2 1.1 0.5 0.9 0.3 -0.3 0.5 -0.0 0.4 -0.7 1.0 -0.9 -0.0 0.5 1.4 0.7 0.8 0.8 1.1 1.3 1.2 1.1 1.0 0.2 1.4 0.6 0.2 0.6 0.1 1.1
Headache pain in last month 0.2 0.3 3.7 -0.4 0.6 1.9 0.3 0.3 0.3 -0.2 0.3 -0.0 -1.4 0.3 0.4 0.3 0.6 0.7 0.3 0.3 0.4 0.6 -0.5 0.3 -0.1 0.2 0.2 0.4 0.2 0.1 -1.2 0.3 0.3 -0.1 0.3 0.3 0.5 0.3 0.7 -0.6 0.3 0.7 0.6 0.5 1.3 0.3
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 1.8 0.9 -1.2 0.9 -0.8 -0.7 -1.1 -0.6 -1.0 -0.8 -0.8 -0.9 -1.1 -0.9 -0.5 -1.1 -0.9 -1.1 -1.0 -1.2 -1.4 -0.4 -0.5 -0.6 0.5 -0.9 -0.4 -0.1 -0.3 0.3 -1.0 0.1 -0.5 -0.8 -0.7 -1.0 -0.8 -0.9 -0.9 -0.8 -1.1 -1.2 0.3 -1.0
Glaucoma (self-reported) 2.6 3.1 7.6 1.9 -1.9 -1.0 -1.8 -1.8 -2.1 -2.6 -2.0 -1.8 -1.1 -2.2 -2.0 -2.1 -2.1 -1.9 -1.7 -2.1 -2.1 -1.7 -1.6 -2.4 -2.8 -1.6 1.4 -1.4 -2.0 -1.9 -0.5 1.3 -2.2 0.7 -0.7 -1.6 -1.2 -2.0 -1.7 -1.1 -1.5 -0.9 -1.4 -1.6 -0.0 -2.0
Gout (self-reported) 4.2 5.7 9.5 2.5 -2.8 -3.1 -2.5 -2.8 -2.8 -2.0 -2.8 -2.4 -1.3 -2.9 -2.7 -2.9 -2.7 -1.9 -3.0 -2.9 -2.8 -2.4 -2.8 -2.3 -1.9 -2.4 1.3 -0.2 -1.8 -2.2 -2.5 1.0 -2.9 0.0 -1.7 -2.3 -2.2 -2.8 -2.5 -2.7 -2.2 -2.2 -2.7 -2.6 0.8 -2.8
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 3.1 -0.6 0.3 0.2 -0.7 0.4 0.4 0.6 -0.3 -0.5 1.8 -0.3 0.4 0.3 -0.2 0.7 0.2 -0.1 0.5 0.4 0.1 0.0 0.7 1.1 -1.0 0.8 0.4 0.5 -0.5 -1.0 0.1 -0.7 -0.4 -0.6 -0.4 -0.2 -0.4 -0.2 -0.7 -0.5 0.2 -0.1 -0.3 -0.3
Medication: Amlodipine 0.7 1.0 4.0 0.3 -0.3 -0.1 -1.5 -1.4 -0.6 -0.8 -1.2 -1.4 -0.8 -0.6 -0.6 -1.0 -1.2 -0.1 -1.3 -1.1 -0.6 0.4 -0.4 -0.7 -1.0 -0.1 -0.3 0.6 -0.3 -2.0 -1.6 -0.8 -1.0 -1.1 -1.3 -1.4 -1.2 -1.2 -1.1 -1.1 -1.3 -1.0 -0.8 -1.1 0.3 -1.2
Medication: Ventolin 100micrograms inhaler 0.2 0.2 1.9 0.2 -0.2 1.4 0.1 -0.1 -0.2 -0.3 0.1 0.4 -0.4 0.0 -0.2 -0.2 0.2 -0.2 0.2 -0.0 -0.2 -0.3 -0.6 -0.8 -0.3 0.3 0.7 -1.4 -0.4 -0.3 0.4 0.8 0.1 0.8 0.4 0.3 0.2 0.0 -0.0 0.5 -0.1 0.2 0.1 0.1 -0.2 0.1
Birth weight 1.0 2.1 5.7 -1.0 1.2 1.0 1.7 1.7 1.4 1.9 1.8 1.8 0.5 1.8 1.4 1.6 1.8 2.0 1.8 1.8 1.4 0.7 1.3 1.1 1.8 0.6 -0.3 -0.1 1.1 2.4 1.5 0.1 1.8 0.3 1.0 1.7 1.4 1.8 1.8 1.3 1.7 1.5 1.3 1.9 0.0 1.8
Chronic bronchitis/emphysema (mother) 1.4 1.6 8.1 -0.0 -0.6 0.5 -1.7 -0.2 -0.6 -0.6 -1.5 -1.8 -0.9 -1.0 -0.6 -0.6 -1.3 -0.2 -0.6 -1.3 -0.6 0.1 -1.2 -0.4 -0.7 0.1 -0.9 -0.3 -0.3 -1.2 -2.8 -1.8 -1.2 -1.7 -2.0 -1.8 -1.7 -1.5 -1.7 -1.6 -2.1 -2.1 -0.9 -1.9 0.5 -1.5
High blood pressure (siblings) 1.0 1.4 4.4 0.2 -0.6 -1.9 -1.6 -0.8 -0.6 -0.9 -1.4 -1.6 -0.1 -1.2 -0.6 -0.8 -1.4 -1.0 -1.2 -1.2 -0.6 0.4 0.1 -0.5 -1.1 0.2 -0.8 0.1 -0.3 -2.1 -2.0 -0.8 -1.1 -1.3 -1.8 -1.6 -1.9 -1.4 -1.4 -0.8 -1.8 -1.2 -0.9 -0.9 -0.9 -1.4
Forced vital capacity (FVC), Best measure 0.8 2.8 5.1 -1.1 1.4 0.1 2.2 2.1 1.6 1.8 2.2 2.2 2.0 2.0 1.5 1.8 1.9 1.1 1.5 2.1 1.5 1.5 1.8 2.0 1.8 0.5 0.1 0.9 1.0 0.9 1.4 0.2 2.0 0.6 1.8 2.1 2.1 2.1 2.2 1.3 2.2 1.9 1.5 1.9 0.9 2.2
Body fat percentage 0.4 1.5 6.2 -0.6 0.1 1.3 -1.8 0.3 0.1 0.3 -1.3 -1.7 -0.4 -0.6 0.1 0.0 -0.8 0.4 -0.6 -1.0 0.2 1.0 0.3 0.5 0.4 1.4 -1.8 1.6 1.3 -1.1 -1.0 -2.0 -0.5 -2.5 -2.4 -1.9 -1.9 -1.2 -1.4 -1.4 -1.8 -1.8 -0.7 -1.0 -0.1 -1.3
Leg fat percentage (right) 0.6 2.1 8.6 -1.2 0.5 1.6 -2.0 0.6 0.4 0.6 -1.4 -1.9 -0.2 -0.5 0.4 0.3 -0.9 0.7 -0.4 -1.0 0.5 1.6 0.6 0.9 0.6 2.1 -2.4 1.6 1.7 -1.4 -1.5 -2.6 -0.3 -2.9 -2.6 -2.2 -2.0 -1.3 -1.4 -1.6 -2.2 -2.0 -0.4 -1.1 0.6 -1.4
Arm fat-free mass (right) 0.7 3.6 9.5 1.5 -1.9 -1.8 -2.3 -0.5 -1.8 -0.8 -2.3 -2.4 -0.4 -2.1 -1.8 -1.4 -2.4 -0.9 -1.4 -2.3 -1.9 -1.4 -1.6 -0.8 -0.8 -1.5 0.4 -0.2 -1.2 -1.6 -0.8 -1.6 -2.1 -1.9 -2.9 -2.4 -2.5 -2.3 -2.4 -3.1 -2.1 -3.1 -2.8 -2.7 0.8 -2.3
Exposure to tobacco smoke outside home 0.3 0.4 1.5 0.7 -0.8 0.6 -0.4 -0.3 -0.7 -0.8 -0.5 -0.3 -0.8 -0.7 -0.8 -0.7 -0.4 -0.5 -0.4 -0.6 -0.7 -0.6 -1.2 -0.9 -0.7 -0.6 0.7 -1.0 -0.2 -1.0 -0.4 0.4 -0.6 0.4 -0.1 -0.3 -0.2 -0.5 -0.6 -0.5 -0.3 -0.6 -0.7 -0.7 -0.3 -0.5
Comparative body size at age 10 4.1 11.2 22.5 1.9 -2.9 -0.8 -4.7 -3.0 -3.0 -2.7 -4.5 -4.7 -2.2 -3.9 -2.9 -3.1 -4.2 -2.2 -3.4 -4.3 -3.0 -1.3 -2.6 -2.1 -2.9 -1.2 -0.9 -1.5 -1.6 -3.6 -1.9 -1.4 -3.9 -2.7 -4.4 -4.6 -4.2 -4.4 -4.2 -4.7 -4.7 -4.4 -3.6 -4.3 0.8 -4.5
Number of full brothers 0.3 0.4 1.5 0.3 -0.3 -1.0 -0.5 -1.0 -0.4 -0.5 -0.6 -0.7 0.1 -0.8 -0.5 -0.7 -0.5 -0.8 -1.1 -0.6 -0.4 -0.4 -0.7 0.0 -0.4 -0.4 -0.2 -0.4 -0.3 0.1 -0.8 -0.2 -0.4 -0.7 -0.9 -0.6 -0.5 -0.6 -0.4 -1.2 -0.4 -0.5 -0.6 -0.4 1.0 -0.6
Worry too long after embarrassment 1.2 1.9 5.6 2.0 -1.9 -0.4 -0.5 -0.9 -1.9 -1.5 -1.0 -0.2 -1.1 -1.5 -1.9 -1.5 -0.9 -1.8 -1.3 -1.3 -1.9 -2.0 -1.8 -2.0 -1.3 -2.1 2.4 -1.7 -2.0 -1.3 -0.8 1.7 -1.5 1.5 0.1 -0.3 -0.6 -1.0 -0.9 -0.4 -0.4 -0.5 -1.7 -1.1 -0.8 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 1.5 -0.5 0.0 0.1 -0.4 -0.1 0.0 0.2 -0.3 -0.8 0.5 -0.1 0.1 0.2 -0.1 0.1 0.0 -0.3 0.0 0.4 0.0 0.2 0.3 -0.3 -0.1 -0.2 0.5 -0.6 -0.9 -1.0 0.1 -1.2 -1.1 -0.6 -0.9 -0.3 -0.1 -1.2 -0.4 -0.7 -0.6 -0.3 -0.3 -0.4
Wheeze or whistling in the chest in last year 0.3 0.6 1.9 -0.3 0.8 0.5 0.9 0.4 0.6 -0.0 0.9 0.9 -0.8 1.0 0.6 0.4 0.8 0.9 0.7 0.9 0.6 0.0 0.5 -0.6 -0.0 0.5 0.4 0.7 0.1 0.5 0.9 0.7 0.7 0.8 1.0 1.0 0.9 0.9 0.8 1.4 0.9 1.1 1.0 1.0 -0.5 0.9
Number of children fathered 0.7 0.7 2.5 -0.1 0.5 -0.7 1.0 0.1 0.6 0.6 0.9 1.0 0.2 0.7 0.5 0.4 1.0 0.7 1.0 0.8 0.6 -0.2 0.5 -0.3 0.6 0.6 -0.1 0.9 0.3 0.9 1.3 1.0 0.8 1.1 1.4 1.0 1.3 0.9 1.1 1.4 1.5 1.6 0.9 1.4 0.1 0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 1.5 -0.8 0.5 0.8 -0.4 0.3 0.5 -0.0 -0.1 -0.5 0.6 0.1 0.6 0.4 -0.0 0.5 0.1 0.0 0.4 0.9 0.8 0.5 0.0 0.3 -1.2 0.7 0.4 -0.3 -0.2 -0.8 0.2 -0.8 -0.2 -0.4 -0.1 -0.0 -0.0 -0.3 -0.3 -0.1 0.4 -0.1 -0.1 -0.1
Age at first live birth 0.5 0.8 4.8 -1.1 1.0 1.2 0.3 0.9 1.1 1.0 0.6 0.5 1.3 0.5 0.9 1.2 0.7 0.4 0.8 0.7 1.0 1.0 1.2 1.4 1.1 0.7 -1.3 -0.9 1.1 2.2 -0.5 -1.7 0.7 -1.2 -0.3 0.2 -0.1 0.6 0.2 0.4 -0.0 -0.3 0.5 0.2 -0.8 0.6
Pulse wave peak to peak time 1.1 1.3 5.9 -0.2 0.5 0.3 1.6 0.2 0.6 0.8 1.5 1.9 -0.7 1.5 0.6 0.4 1.1 1.0 0.9 1.3 0.6 -0.3 0.5 -0.1 0.8 -0.6 0.9 -0.5 0.7 1.2 1.4 1.2 1.0 1.5 1.5 1.8 1.0 1.5 1.1 2.4 1.3 1.2 0.8 1.2 -2.0 1.5
Health satisfaction 0.1 0.2 0.7 0.0 -0.0 -0.4 -0.6 0.2 -0.1 -0.1 -0.4 -0.4 -0.5 -0.3 -0.0 0.0 -0.4 -0.3 -0.3 -0.2 -0.1 0.3 0.2 0.1 -0.2 -0.0 -0.2 0.1 0.3 -0.4 -0.5 -0.7 -0.3 -0.9 -0.8 -0.5 -0.6 -0.3 -0.5 -0.4 -0.5 -0.7 -0.4 -0.4 -0.5 -0.3
Shortness of breath walking on level ground 0.2 0.2 2.0 0.5 -0.3 -0.4 0.2 0.2 -0.3 -0.2 0.1 0.2 -0.1 -0.3 -0.3 -0.1 0.1 -1.4 -0.3 0.0 -0.3 -0.2 -0.1 0.3 -0.3 -0.7 0.4 -1.4 -0.4 0.3 0.7 0.0 -0.2 0.0 -0.2 0.2 -0.3 0.1 -0.2 -0.0 0.2 -0.3 -0.5 -0.1 -1.3 0.1
Qualifications: College or University degree 0.1 0.4 3.2 -0.5 0.5 0.0 1.0 0.2 0.6 0.5 0.9 0.6 1.8 0.8 0.7 0.5 0.7 1.1 0.6 0.8 0.5 0.3 0.4 0.3 0.4 -0.5 -0.2 0.3 -0.2 0.6 -0.7 -0.1 0.6 0.1 0.7 0.8 0.6 0.8 0.7 0.4 0.8 0.5 0.6 0.6 -0.0 0.9
Eye problems/disorders: None of the above 0.7 0.8 1.9 -0.7 0.8 0.2 1.2 0.9 0.9 1.1 1.2 1.1 0.9 1.0 0.9 1.0 1.2 0.8 0.8 1.2 0.9 0.6 0.7 1.1 1.1 0.1 -0.1 0.2 0.4 1.4 0.5 -0.3 1.1 -0.1 0.5 1.1 0.9 1.1 1.1 0.7 1.1 0.7 0.8 1.0 0.7 1.2
Mouth/teeth dental problems: Loose teeth 2.2 2.7 7.7 -2.3 2.1 1.0 0.5 2.8 2.0 1.7 0.9 0.1 2.3 1.5 2.1 2.3 1.6 2.6 1.9 1.2 2.0 2.3 1.8 2.4 1.7 1.9 -2.3 1.1 2.4 1.3 -1.2 -2.0 1.6 -1.5 0.2 0.1 0.9 1.0 0.9 0.4 0.4 0.4 1.6 0.8 0.7 0.9
Emphysema/chronic bronchitis 1.4 1.6 3.2 -1.4 1.4 1.6 1.3 1.3 1.4 1.4 1.5 1.4 -0.2 1.6 1.4 1.4 1.2 1.8 1.4 1.5 1.4 1.1 1.5 1.4 1.3 1.2 -0.6 1.1 1.4 0.7 0.9 -0.2 1.4 0.2 1.2 1.2 1.3 1.5 1.3 1.0 0.6 1.0 1.6 0.9 0.9 1.5
Medication for pain relief, constipation, heartburn 0.9 1.5 3.3 -1.6 1.4 0.5 0.7 1.2 1.5 1.7 1.1 0.7 0.8 1.5 1.5 1.4 0.9 1.0 1.1 1.2 1.5 1.6 1.6 1.8 1.7 1.6 -1.7 1.8 1.6 1.0 0.9 -1.2 1.2 -0.7 0.5 0.6 0.6 1.1 1.0 1.2 0.4 0.8 1.3 0.9 -0.1 1.1
Neck or shoulder pain in last month 0.9 1.3 5.8 1.5 -1.3 -1.4 0.5 -0.9 -1.2 -1.4 -0.1 0.6 -1.3 -0.6 -1.2 -1.1 -0.3 -1.1 -0.6 -0.3 -1.2 -1.8 -1.5 -1.7 -1.4 -1.5 2.4 -2.3 -1.7 0.4 0.4 2.1 -0.7 1.8 0.9 0.6 0.3 -0.1 -0.1 0.4 0.2 0.4 -0.5 -0.1 -0.9 -0.1
Medication: Blood pressure 0.3 0.6 2.9 -0.2 0.3 -1.0 -1.0 -0.1 -0.1 -0.3 -0.7 -1.1 0.7 -0.5 0.0 -0.1 -1.0 0.2 -0.3 -0.6 -0.1 0.8 0.4 -0.4 -0.4 0.1 -0.7 1.6 -0.0 -1.7 -1.5 -0.9 -0.4 -1.2 -1.1 -1.0 -0.9 -0.7 -0.8 -0.8 -0.8 -0.8 -0.3 -0.5 -0.0 -0.7
Angina (self-reported) 0.9 1.2 3.8 1.3 -0.9 -1.9 -0.6 -2.0 -1.1 -1.7 -0.8 -0.6 -0.5 -1.0 -1.1 -1.6 -1.2 -1.1 -1.5 -0.9 -1.1 -1.0 -1.4 -1.9 -1.9 -1.0 1.2 0.2 -0.9 -1.6 -1.3 1.4 -1.3 0.7 -0.0 -0.4 -0.6 -0.8 -0.8 -0.0 -0.6 -0.0 -0.5 -0.5 -0.7 -0.8
Migraine (self-reported) 0.3 0.4 3.1 -0.3 0.6 0.5 0.5 -0.2 0.5 0.4 0.5 0.6 -0.5 0.4 0.5 0.3 0.7 -0.6 0.2 0.5 0.6 1.0 0.1 0.3 0.7 0.6 0.3 0.8 0.3 -0.4 -1.8 0.1 0.6 0.3 0.5 0.5 0.4 0.5 0.5 0.8 0.5 0.6 0.4 0.8 -1.5 0.5
Medication: Ibuprofen 1.7 2.0 5.6 1.2 -1.7 -2.2 -1.4 -1.4 -1.5 -1.6 -1.6 -1.6 -0.4 -1.7 -1.4 -1.5 -1.3 -0.8 -1.4 -1.6 -1.6 -1.2 -1.3 -1.3 -1.7 -1.9 1.1 -1.2 -1.2 -0.9 -0.9 0.1 -1.5 -0.7 -1.5 -1.4 -1.3 -1.6 -1.3 -2.4 -1.0 -1.4 -1.7 -1.4 0.8 -1.6
Medication: Allopurinol 2.8 3.7 9.4 2.4 -2.4 -3.1 -1.5 -2.5 -2.4 -1.9 -2.0 -1.4 -1.3 -2.2 -2.4 -2.5 -1.9 -1.6 -2.3 -2.1 -2.4 -2.5 -2.4 -2.5 -1.9 -2.3 1.9 -0.8 -1.6 -1.1 -1.0 1.8 -2.3 0.7 -0.8 -1.3 -1.2 -1.9 -1.7 -2.0 -1.2 -1.2 -2.1 -1.7 1.0 -1.9
Medication: Omeprazole 0.3 0.3 2.0 -0.2 -0.2 -0.9 -0.8 -0.2 -0.2 -0.6 -0.5 -0.7 0.3 -0.5 -0.3 -0.3 -0.3 -0.2 -0.3 -0.5 -0.2 0.1 -0.4 0.1 -0.5 -0.1 -0.4 -1.4 0.2 -0.4 -1.3 -0.5 -0.5 -0.6 -0.6 -0.7 -0.7 -0.5 -0.6 -0.6 -0.8 -0.7 -0.2 -0.7 0.0 -0.5
Medication: Seretide 50 evohaler 0.4 0.5 2.0 -0.9 0.6 -0.6 0.1 1.4 0.7 1.0 0.4 0.2 0.7 0.5 0.7 1.1 0.4 0.6 1.0 0.4 0.7 1.1 1.1 0.7 1.2 1.2 -1.1 0.4 0.6 -0.7 -0.1 -1.3 0.5 -0.6 -0.0 0.0 0.1 0.4 0.2 0.3 -0.3 -0.2 0.5 -0.1 0.4 0.4
Mean time to correctly identify matches 0.1 0.3 1.0 -0.1 0.4 -0.4 0.5 0.3 0.3 0.2 0.5 0.7 -0.5 0.3 0.3 0.3 0.6 -0.1 0.4 0.4 0.3 -0.1 0.7 0.2 0.2 0.0 -0.3 0.7 0.2 0.8 0.7 0.9 0.4 0.8 1.0 0.6 0.9 0.5 0.4 0.8 0.5 0.8 0.7 0.5 0.6 0.5
Heart disease (mother) 0.2 0.2 2.9 0.0 -0.1 -1.7 -0.3 -0.4 -0.0 -0.2 -0.3 -0.5 -0.5 -0.4 -0.0 -0.4 -0.3 -0.2 -0.7 -0.3 -0.1 0.3 0.2 0.2 -0.3 -0.5 0.2 0.8 -0.4 -0.6 -0.9 -0.4 -0.3 -0.5 -0.7 -0.5 -0.7 -0.3 -0.2 -0.2 -0.5 -0.2 -0.2 -0.1 -0.5 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.2 2.7 5.8 1.0 -1.5 -1.0 -1.8 -1.6 -1.6 -1.5 -2.0 -2.0 -1.6 -1.9 -1.5 -1.7 -2.3 -1.6 -1.8 -1.9 -1.6 -1.2 -1.3 -1.4 -1.4 -0.5 0.1 -0.1 -1.1 -2.1 -1.8 -0.3 -1.9 -0.6 -1.5 -1.9 -1.9 -2.0 -2.1 -1.6 -2.4 -2.0 -1.6 -2.3 0.1 -2.0
Whole body fat mass 0.5 2.0 8.2 0.0 -0.6 0.4 -2.2 -0.1 -0.5 -0.1 -1.8 -2.1 -0.6 -1.2 -0.6 -0.6 -1.4 -0.1 -1.1 -1.5 -0.5 0.3 -0.4 0.1 -0.1 0.6 -1.3 1.0 0.5 -1.4 -0.9 -2.1 -1.1 -2.6 -2.9 -2.2 -2.3 -1.7 -1.9 -2.1 -2.1 -2.4 -1.5 -1.6 0.0 -1.8
Leg fat mass (right) 0.5 1.9 7.9 -0.5 -0.2 0.7 -2.0 0.4 -0.1 0.3 -1.6 -2.0 -0.5 -0.8 -0.1 -0.1 -1.2 0.4 -0.6 -1.3 -0.1 0.8 0.1 0.5 0.4 1.1 -1.7 1.0 1.0 -1.2 -1.0 -2.4 -0.7 -2.8 -2.8 -2.1 -2.1 -1.5 -1.6 -2.0 -2.1 -2.4 -1.1 -1.5 0.5 -1.6
Arm predicted mass (right) 0.5 2.6 8.1 1.0 -1.5 -1.5 -2.0 -0.1 -1.3 -0.3 -1.9 -2.1 -0.1 -1.7 -1.3 -0.9 -2.0 -0.5 -1.0 -1.9 -1.4 -1.0 -1.1 -0.4 -0.3 -1.1 0.0 0.2 -0.8 -1.2 -0.7 -1.9 -1.7 -2.1 -2.7 -2.1 -2.2 -1.9 -2.0 -2.8 -1.8 -2.8 -2.4 -2.3 0.9 -1.9
Pulse rate, automated reading 1.5 4.8 12.1 -1.8 2.4 -1.0 2.5 2.7 2.3 2.6 2.7 2.6 3.5 2.3 2.4 2.5 2.8 2.2 2.3 2.7 2.4 1.7 2.0 2.1 2.5 1.4 -0.4 1.1 1.4 1.3 0.7 -0.3 2.5 0.7 2.0 2.5 2.4 2.7 2.5 2.5 2.1 2.2 2.5 2.4 0.7 2.7
Alcohol intake frequency. 2.0 4.7 13.5 -3.2 2.7 3.7 0.9 3.1 2.6 2.6 1.4 0.9 0.4 2.1 2.7 2.9 1.9 2.6 2.1 1.8 2.7 3.4 2.5 3.5 2.6 3.2 -2.6 1.7 3.0 1.1 -0.3 -2.2 2.3 -1.5 0.1 0.5 0.8 1.5 1.4 1.0 0.1 0.7 2.4 1.4 1.2 1.4
Comparative height size at age 10 0.2 0.8 4.0 -0.4 0.6 -1.2 0.9 2.0 0.8 1.3 1.0 1.1 1.0 0.9 0.7 1.3 0.8 0.7 1.7 1.0 0.8 0.3 1.1 1.1 1.3 0.3 0.5 -0.4 0.5 1.4 1.0 -0.6 0.9 -0.3 0.2 0.9 0.5 1.0 0.8 0.7 0.9 0.4 0.4 0.9 -0.2 1.0
Number of full sisters 0.3 0.4 1.5 -0.8 0.5 0.2 -0.3 0.7 0.5 0.4 -0.2 -0.9 0.0 0.2 0.6 0.6 0.2 0.4 0.6 -0.1 0.5 0.9 0.3 0.4 0.4 0.9 -1.2 0.8 1.0 -0.4 -1.1 -1.1 0.2 -1.2 -0.6 -0.7 -0.2 -0.2 0.1 -0.7 -0.3 -0.2 0.1 -0.1 0.8 -0.2
Suffer from ‘nerves’ 0.1 0.2 1.1 -0.8 0.5 0.6 -0.0 0.2 0.5 0.4 0.2 0.1 0.5 0.2 0.5 0.4 0.7 0.4 0.4 0.2 0.5 0.6 0.5 0.3 0.6 0.3 -0.4 0.0 1.0 0.6 -0.3 -0.6 0.5 -0.7 -0.1 -0.1 -0.1 0.2 0.1 -0.0 0.0 -0.1 0.2 0.1 -0.5 0.2
Overall health rating 0.1 0.2 1.8 0.4 -0.1 -1.3 -0.2 -0.2 -0.3 -0.4 -0.2 -0.1 -0.3 -0.2 -0.3 -0.5 -0.3 -0.2 -0.6 -0.2 -0.3 0.0 -0.3 -0.7 -0.4 -0.4 0.7 0.3 -0.1 -1.0 -0.9 -0.2 -0.6 -0.2 -0.2 -0.2 -0.4 -0.2 -0.5 -0.1 -0.6 -0.4 -0.3 -0.6 -0.6 -0.2
Chest pain or discomfort 0.3 0.5 3.7 0.1 0.3 0.0 1.0 0.5 0.1 -0.1 0.7 1.0 0.3 0.7 0.2 0.3 0.4 0.5 0.2 0.5 0.1 0.2 -0.3 -0.3 -0.1 -0.5 1.1 0.8 -0.1 -0.9 -1.2 0.8 0.3 1.1 1.0 1.0 0.4 0.7 0.3 1.5 0.6 0.6 0.4 0.5 -1.9 0.7
Had major operations 0.0 0.1 0.7 -0.1 0.1 0.3 -0.3 0.0 0.1 -0.2 -0.2 -0.3 0.2 -0.4 0.0 -0.1 0.2 -0.8 -0.2 -0.2 0.1 -0.1 -0.1 0.1 -0.1 0.4 -0.4 0.0 -0.1 0.5 -0.3 -0.4 -0.1 -0.2 -0.1 -0.3 -0.1 -0.2 -0.0 0.2 -0.1 0.1 0.1 -0.0 -0.2 -0.2
Age at last live birth 0.2 0.3 3.4 -0.3 0.3 0.4 -0.0 0.4 0.4 0.3 0.2 0.2 -0.2 0.2 0.3 0.5 0.2 -0.1 0.3 0.2 0.3 0.5 0.5 0.7 0.3 -0.1 -0.9 -1.7 0.4 1.8 -0.2 -0.7 0.2 -0.3 -0.2 -0.0 -0.3 0.2 0.1 0.7 -0.0 0.1 0.2 0.2 -1.0 0.2
Family relationship satisfaction 0.9 1.1 3.5 -0.8 1.1 0.2 1.2 0.6 1.2 0.8 1.3 1.2 1.4 1.2 1.1 1.0 1.1 0.4 1.2 1.3 1.2 0.7 1.1 0.6 0.7 0.5 -0.7 -0.2 0.8 1.9 1.6 0.0 1.1 0.2 1.0 1.2 1.1 1.3 1.2 1.2 1.2 1.2 1.3 1.4 -0.2 1.3
Leg pain on walking 0.2 0.3 2.0 0.5 -0.3 -1.4 -0.3 -0.4 -0.5 -0.7 -0.4 -0.3 0.3 -0.5 -0.5 -0.4 -0.3 0.1 -0.4 -0.4 -0.5 -0.3 -0.6 -0.3 -0.7 -0.4 0.4 -0.9 -0.7 -0.8 -1.1 0.3 -0.4 0.3 0.1 -0.3 0.2 -0.4 -0.2 -0.6 -0.3 -0.0 -0.2 -0.5 1.4 -0.4
Qualifications: NVQ or HND or HNC or equivalent 2.2 2.6 8.2 1.9 -1.8 -0.0 -0.9 -2.0 -1.9 -1.8 -1.3 -1.0 -2.9 -1.4 -1.8 -2.2 -1.7 -1.6 -2.2 -1.5 -1.9 -1.8 -2.0 -1.8 -1.8 -1.4 1.5 -1.3 -2.1 -2.0 -0.2 0.6 -1.8 0.3 -0.9 -0.7 -1.4 -1.3 -1.7 -0.8 -1.3 -1.6 -1.9 -1.8 -1.9 -1.3
Commuting to job workplace: Car/motor vehicle 0.8 0.9 2.6 -0.8 1.2 0.1 1.0 -0.4 1.2 1.4 1.2 1.0 -0.4 1.2 1.2 0.6 1.1 0.9 0.8 1.3 1.2 0.4 0.9 0.6 1.4 1.0 -0.6 1.6 1.0 1.1 0.2 -0.7 1.2 -0.6 0.3 1.0 0.7 1.3 1.0 0.7 1.0 0.6 0.7 1.1 -0.6 1.2
Illness, injury, bereavement, stress in last 2 years 2.1 2.6 6.5 -0.6 1.3 0.4 2.3 0.5 1.2 0.9 2.1 2.3 0.8 1.8 1.2 1.0 1.9 0.8 1.3 2.0 1.2 0.2 1.2 1.0 1.0 0.4 0.6 0.0 0.8 1.2 2.5 1.8 1.7 1.7 2.4 2.3 2.3 2.1 2.2 1.9 2.4 2.4 1.8 2.3 0.1 2.1
Medication: Aspirin 0.1 0.1 0.9 0.4 -0.0 0.2 -0.2 0.1 -0.2 -0.1 -0.2 -0.1 0.0 -0.3 -0.2 -0.1 -0.3 0.0 -0.1 -0.3 -0.2 -0.1 -0.2 -0.5 -0.2 -0.0 0.1 0.6 0.0 -1.0 -0.2 0.5 -0.2 0.2 0.0 -0.2 0.1 -0.3 -0.2 -0.4 -0.0 -0.1 -0.1 0.0 0.2 -0.3
Supplements: Vitamin C 0.3 0.4 1.5 0.5 -0.6 -0.4 -0.2 -0.4 -0.6 -0.8 -0.3 -0.3 -0.5 -0.3 -0.6 -0.5 -0.5 -0.1 -0.9 -0.4 -0.6 -0.7 -0.3 -0.1 -0.9 -1.0 0.7 -0.4 -0.9 -1.1 -1.2 -0.0 -0.6 -0.2 -0.6 -0.1 -0.8 -0.3 -0.6 -0.3 -0.5 -0.6 -0.7 -0.5 -1.2 -0.3
Knee pain experienced in last month 0.2 0.4 1.5 0.9 -0.7 -1.2 -0.2 -0.5 -0.8 -0.4 -0.4 -0.2 -1.0 -0.5 -0.7 -0.8 -0.6 0.5 -0.6 -0.5 -0.8 -0.9 -0.4 -0.9 -0.3 -0.9 0.7 -0.6 -0.7 -0.8 0.2 0.8 -0.4 0.6 -0.1 -0.1 -0.0 -0.4 -0.3 -0.6 -0.0 -0.3 -0.6 -0.3 0.5 -0.4
Hypertension (Self-reported) 0.7 2.0 6.5 1.9 -1.2 -2.5 0.1 -1.9 -1.5 -2.2 -0.3 0.1 0.4 -1.0 -1.4 -1.9 -1.0 -1.6 -1.9 -0.6 -1.6 -1.3 -1.1 -2.1 -2.3 -2.5 2.2 -0.7 -2.2 -1.8 0.4 1.8 -1.1 1.4 0.3 0.4 -0.3 -0.3 -0.5 0.3 0.5 0.1 -1.1 -0.2 -2.4 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.2 3.5 1.4 -1.3 -0.4 -0.4 -1.1 -1.3 -1.9 -0.7 -0.1 -0.9 -1.1 -1.4 -1.3 -0.9 -1.5 -1.2 -0.8 -1.2 -1.1 -1.7 -1.3 -1.6 -0.8 1.4 -1.4 -1.3 -1.2 -0.5 1.3 -1.2 1.1 0.3 -0.2 -0.5 -0.7 -1.0 0.4 -0.5 -0.3 -0.8 -0.9 -1.4 -0.7
Illnesses of father: Heart disease 1.0 1.3 5.1 0.5 0.1 -1.1 1.5 -0.6 0.1 0.0 1.3 1.8 -1.4 1.0 0.2 -0.1 1.1 0.7 0.5 1.0 0.1 -1.0 -0.5 -0.6 0.2 -0.4 1.6 -0.6 -0.7 1.4 0.4 1.9 0.8 2.3 2.0 1.9 1.7 1.3 1.1 1.7 1.7 1.5 0.7 1.2 -0.3 1.3
Illnesses of siblings: Diabetes 1.4 1.7 9.4 -1.5 0.8 0.7 -1.1 1.7 0.9 0.9 -0.6 -1.4 1.0 -0.0 0.9 1.2 -0.0 0.8 0.3 -0.3 1.0 2.0 0.9 2.1 0.8 1.4 -2.2 1.6 1.9 -0.2 -1.1 -2.8 0.2 -3.1 -2.1 -1.6 -1.1 -0.6 -0.5 -1.6 -1.0 -1.2 -0.1 -0.4 1.2 -0.7
Smoking status: Previous 0.3 0.4 1.3 -1.0 1.0 0.1 0.3 0.2 0.9 0.8 0.6 0.1 0.8 0.6 1.0 0.7 0.7 0.3 0.4 0.7 0.9 0.6 0.7 1.1 0.7 0.7 -1.0 1.0 0.6 0.3 -0.1 -1.1 0.8 -0.6 -0.2 0.2 0.0 0.6 0.6 0.5 0.3 0.4 0.6 0.6 -0.3 0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 2.1 0.2 0.3 -0.4 1.3 0.8 0.3 0.5 1.1 1.3 0.1 0.9 0.2 0.5 0.7 0.9 0.7 1.0 0.2 -0.2 0.3 0.0 0.5 -0.8 1.2 0.8 -0.6 0.5 0.7 0.3 0.5 0.8 1.2 1.4 0.9 1.1 0.8 0.9 1.1 0.6 0.4 0.5 -0.5 1.1
Whole body fat-free mass 0.9 5.4 12.0 2.1 -2.6 -2.0 -2.6 -1.4 -2.4 -1.4 -2.8 -2.7 -1.0 -2.5 -2.4 -2.1 -2.9 -1.4 -2.0 -2.8 -2.5 -1.9 -2.3 -1.4 -1.4 -2.0 0.7 -0.5 -1.9 -2.1 -1.1 -1.4 -2.7 -1.9 -3.2 -2.6 -3.0 -2.8 -2.9 -3.3 -2.4 -3.5 -3.4 -3.1 0.2 -2.8
Leg fat-free mass (right) 0.9 4.8 10.6 2.2 -2.6 -1.9 -2.3 -1.7 -2.4 -1.6 -2.5 -2.4 -1.2 -2.3 -2.4 -2.3 -2.7 -1.5 -2.2 -2.6 -2.5 -2.1 -2.3 -1.6 -1.6 -2.1 1.0 -0.5 -1.9 -1.9 -0.7 -0.9 -2.6 -1.4 -2.7 -2.2 -2.7 -2.5 -2.7 -2.8 -2.0 -3.1 -3.3 -2.9 -0.3 -2.5
Arm fat percentage (left) 0.5 2.1 8.1 -0.2 -0.3 0.9 -2.2 -0.1 -0.3 -0.1 -1.8 -2.2 -0.7 -1.0 -0.3 -0.4 -1.2 0.0 -1.1 -1.5 -0.3 0.7 -0.2 0.3 -0.1 1.0 -1.8 1.4 0.8 -1.5 -1.2 -2.1 -1.0 -2.7 -2.8 -2.3 -2.3 -1.7 -1.8 -1.9 -2.1 -2.3 -1.3 -1.5 -0.4 -1.8
Average weekly red wine intake 0.5 0.8 4.7 -1.1 0.9 2.2 0.2 0.9 1.0 1.4 0.6 0.2 0.6 0.8 1.0 1.1 0.3 0.4 0.7 0.6 1.0 0.9 1.3 1.2 1.3 0.8 -1.1 1.4 0.8 0.6 0.6 -1.7 0.8 -0.9 -0.3 0.1 -0.3 0.5 0.3 0.6 0.0 -0.3 0.3 0.3 -1.0 0.5
Handedness (chirality/laterality): Left-handed 1.7 2.1 5.7 0.3 -0.8 -2.2 -2.0 -0.6 -0.8 -0.3 -1.7 -2.0 0.8 -1.2 -0.8 -0.7 -1.4 -0.2 -1.5 -1.6 -0.8 0.6 -0.2 -0.2 -0.2 -0.8 -0.9 0.4 -0.1 -2.0 -1.4 -1.9 -1.2 -2.1 -2.4 -2.0 -2.0 -1.7 -1.7 -2.3 -1.9 -2.3 -1.7 -1.8 0.1 -1.7
Mood swings 0.4 0.8 3.3 1.2 -0.8 -1.0 0.3 -1.1 -0.9 -1.4 0.0 0.4 0.6 -0.5 -0.8 -1.1 -0.0 -0.3 -0.8 -0.2 -0.9 -1.1 -0.8 -1.5 -1.2 -1.8 1.6 -1.8 -1.3 -0.6 0.5 1.7 -0.5 1.3 0.7 0.5 0.5 0.0 0.1 -0.2 0.4 0.5 -0.3 -0.0 0.1 0.1
Loneliness, isolation 1.9 2.6 4.5 1.2 -1.8 -1.8 -1.8 -1.3 -1.6 -1.4 -1.9 -1.8 -0.8 -2.0 -1.7 -1.6 -1.6 -1.5 -1.7 -1.9 -1.7 -0.8 -1.3 -1.4 -1.3 -1.7 0.9 -1.6 -1.3 -1.5 -1.2 -0.4 -1.9 -1.0 -2.0 -1.9 -2.1 -1.9 -1.8 -2.1 -2.0 -1.9 -2.0 -1.9 -0.3 -1.9
Long-standing illness, disability or infirmity 0.5 0.7 4.5 1.0 -0.8 -2.1 0.4 -0.8 -0.8 -1.0 0.1 0.7 -0.1 -0.3 -0.8 -0.9 -0.1 -0.9 -0.8 -0.1 -0.8 -0.8 -0.6 -1.2 -1.0 -1.2 1.5 -1.6 -0.8 -0.5 0.4 2.0 -0.3 1.5 0.7 0.6 0.5 0.1 0.2 0.3 0.4 0.6 -0.0 0.2 0.6 0.1
Ever had bowel cancer screening 0.7 0.8 2.8 -0.0 0.5 0.3 1.3 0.2 0.6 0.4 1.1 1.2 0.0 0.8 0.5 0.5 1.3 0.9 0.3 1.0 0.6 -0.0 0.4 0.7 0.4 -0.1 0.2 -0.5 0.1 1.1 0.3 1.1 1.0 1.3 1.3 1.2 1.5 1.1 1.3 1.2 1.6 1.7 0.9 1.5 0.3 1.1
Diabetes diagnosed by doctor 0.2 0.3 1.5 0.5 -0.0 -0.7 0.7 -0.0 -0.1 -0.7 0.5 0.5 0.1 0.2 -0.1 -0.1 0.4 -0.1 -0.3 0.4 -0.2 -0.3 -0.8 0.0 -0.8 -1.2 0.9 -0.3 -0.4 0.3 -1.0 0.5 -0.1 0.2 0.4 0.7 0.7 0.5 0.3 -0.2 0.7 0.4 0.0 0.1 0.6 0.6
Ever had stillbirth, spontaneous miscarriage or termination 1.8 1.9 4.8 1.0 -1.0 -1.4 -1.5 -1.3 -1.2 -0.8 -1.6 -1.7 0.6 -1.6 -1.1 -1.3 -1.7 -1.1 -2.0 -1.6 -1.2 -0.6 -1.2 -0.8 -0.9 -1.0 0.0 1.1 -0.4 -1.8 -2.2 -0.4 -1.5 -1.0 -1.9 -1.7 -2.0 -1.6 -1.7 -1.6 -1.6 -1.8 -1.6 -1.4 -0.7 -1.6
Friendships satisfaction 0.2 0.3 3.4 -0.5 0.7 1.8 -0.1 0.5 0.5 0.4 0.1 -0.3 0.6 0.3 0.6 0.5 0.3 0.5 0.7 0.2 0.5 0.7 0.1 0.7 0.4 0.2 -0.5 0.9 0.4 0.5 -0.3 -0.8 0.3 -0.9 -0.1 -0.2 0.3 0.1 0.2 -0.7 0.4 -0.0 0.1 0.2 0.4 0.1
Qualifications: nursing, teaching 0.4 0.6 2.1 0.5 0.1 -0.4 1.3 0.1 -0.1 -0.1 0.9 1.1 -0.2 1.0 0.0 -0.1 0.7 0.6 -0.1 0.7 -0.1 -0.8 -0.5 -0.1 -0.2 -1.1 1.2 0.2 -1.0 0.6 -0.0 1.1 0.4 1.4 1.4 1.3 1.0 0.9 0.8 1.0 1.4 1.0 0.2 0.8 -0.6 0.9
Commuting to job workplace: Walk 0.7 0.7 3.1 1.1 -0.9 -0.3 -0.1 -0.8 -1.0 -1.7 -0.5 -0.2 -0.9 -0.7 -1.0 -1.0 -0.6 -1.3 -1.1 -0.7 -1.1 -0.8 -1.0 -0.9 -1.8 -0.8 0.9 -0.8 -1.5 -0.9 -0.1 1.1 -0.8 1.0 0.2 -0.1 -0.3 -0.5 -0.7 0.4 -0.1 -0.0 -0.5 -0.4 -1.4 -0.5
Eye problems/disorders: Cataract 0.7 0.8 2.3 -1.3 1.1 1.4 0.2 0.9 1.2 0.7 0.6 0.2 -0.2 1.1 1.2 1.1 1.0 1.5 1.1 0.7 1.1 1.3 0.8 1.0 0.9 1.5 -1.3 0.9 1.2 0.7 -0.1 -0.7 1.0 -0.2 0.8 0.2 1.0 0.6 0.7 0.3 0.4 0.6 1.2 0.6 0.4 0.6
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 4.8 -0.4 0.6 -0.3 1.7 0.5 0.7 0.7 1.6 2.1 0.8 1.3 0.6 0.6 1.2 1.0 0.4 1.4 0.7 -0.2 0.3 0.4 0.8 -0.1 1.0 -0.9 0.1 0.8 0.5 1.1 1.0 1.8 2.2 2.0 1.8 1.6 1.1 1.9 1.2 1.2 1.3 0.9 -0.2 1.6
Medication for cholesterol 0.5 0.8 3.4 -1.5 0.9 0.1 -0.1 0.5 1.1 1.0 0.3 -0.2 0.4 0.6 1.1 0.9 0.4 1.4 1.4 0.5 1.2 0.7 1.1 1.0 1.0 1.7 -1.9 0.9 1.0 1.4 0.2 -1.3 0.8 -1.0 -0.0 -0.2 0.2 0.3 0.2 0.1 -0.3 -0.1 1.0 0.2 0.8 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.8 3.6 1.3 -0.8 -1.1 0.6 -0.5 -0.9 -0.6 0.2 0.7 -1.6 -0.2 -0.8 -0.6 0.2 -0.8 -0.3 -0.1 -0.9 -1.3 -0.8 -0.8 -0.7 -1.2 1.9 -1.9 -1.6 0.3 0.4 1.6 -0.3 1.6 0.7 0.8 0.5 0.2 0.2 0.3 0.7 0.4 -0.6 0.1 -0.2 0.2
Back pain experienced in last month 2.4 3.5 11.4 2.7 -2.3 -1.9 -0.3 -2.0 -2.3 -2.5 -1.0 -0.0 -1.8 -1.6 -2.3 -2.4 -1.9 -2.1 -2.0 -1.3 -2.4 -2.6 -2.0 -2.7 -2.6 -2.4 3.4 -2.1 -2.0 -1.6 0.4 2.6 -2.0 2.1 0.4 0.1 -0.6 -1.0 -1.4 0.0 -0.7 -0.6 -1.5 -1.4 -1.5 -1.0
Mineral and other dietary supplements 0.2 0.3 1.2 -0.3 0.6 -1.1 0.8 0.3 0.4 0.4 0.7 0.7 0.3 0.6 0.4 0.4 0.5 0.2 0.5 0.7 0.5 0.1 0.9 0.6 0.4 -0.2 -0.1 0.5 -0.1 0.1 0.1 -0.3 0.4 -0.1 0.6 0.8 0.8 0.7 0.6 0.1 0.9 0.4 0.3 0.2 0.8 0.8
Breast cancer (self-reported) 0.1 0.1 1.3 0.3 -0.4 -0.1 0.1 0.4 -0.3 -0.4 -0.0 0.0 -0.7 -0.1 -0.3 0.0 0.3 -0.1 0.1 -0.1 -0.3 -0.5 -0.6 -0.1 -0.2 -0.8 0.7 -1.1 -0.4 0.1 -0.2 -0.1 -0.3 -0.0 -0.1 0.1 -0.1 -0.0 -0.3 -0.0 -0.2 -0.4 -0.3 -0.5 -0.3 -0.0
Asthma (self-reported) 0.1 0.3 1.4 0.3 0.1 0.5 0.5 -0.7 -0.0 -0.4 0.5 0.6 0.1 0.3 0.0 -0.3 0.4 0.3 -0.2 0.4 -0.0 -0.2 -0.2 -1.0 -0.6 -0.5 0.8 -0.1 -0.4 -0.1 1.2 0.8 0.1 0.9 0.7 0.7 0.6 0.5 0.4 0.7 0.7 0.8 0.4 0.5 0.0 0.5
Osteoporosis (self-reported) 1.3 1.6 3.9 1.5 -1.5 -1.9 -0.5 -1.7 -1.4 -2.0 -0.7 -0.5 -0.9 -0.9 -1.4 -1.7 -0.7 -1.5 -1.5 -0.9 -1.5 -1.4 -1.3 -1.8 -1.9 -1.9 1.7 -1.5 -1.6 -1.1 0.0 1.0 -1.3 0.5 -0.2 -0.2 -0.7 -0.7 -0.9 -0.6 -0.3 -0.7 -1.3 -1.1 -1.7 -0.7
Osteoarthritis (self-reported) 0.1 0.1 1.6 -0.1 0.1 0.3 -0.1 -0.7 0.1 0.3 0.0 0.1 -1.2 0.1 0.1 -0.1 -0.0 0.1 -0.2 0.0 0.1 0.4 0.2 -0.0 0.5 0.2 -0.3 -0.1 0.0 -0.0 0.2 -0.3 0.2 -0.2 -0.1 -0.0 -0.0 0.0 -0.0 0.1 -0.1 -0.2 -0.1 -0.0 -0.4 0.0
Medication: Aspirin 0.1 0.1 1.1 0.6 -0.2 0.2 -0.4 0.2 -0.4 -0.2 -0.3 -0.2 -0.2 -0.4 -0.4 -0.2 -0.4 -0.1 -0.2 -0.4 -0.4 -0.2 -0.3 -0.6 -0.2 -0.2 0.3 0.3 -0.4 -1.1 0.2 0.5 -0.3 0.3 -0.0 -0.3 0.0 -0.4 -0.3 -0.5 0.0 -0.2 -0.4 -0.1 0.1 -0.4
Medication: Gliclazide 0.4 0.5 3.8 -0.5 0.9 -0.4 0.7 0.2 0.7 0.5 0.7 0.5 1.9 0.6 0.7 0.6 0.7 0.6 0.0 0.7 0.7 0.6 0.6 1.1 0.7 0.3 -0.2 0.1 0.5 -0.2 0.1 0.0 0.6 0.3 0.9 0.6 1.1 0.7 0.7 0.1 0.5 0.6 0.8 0.4 0.9 0.7
Illnesses of father: None of the above (group 1) 0.5 0.6 2.8 -0.2 -0.2 0.2 -1.2 0.3 -0.2 -0.2 -0.8 -1.2 0.8 -0.5 -0.2 0.0 -0.7 0.2 -0.4 -0.7 -0.2 0.7 0.3 0.5 -0.2 0.0 -1.0 0.7 0.4 -0.8 -0.8 -1.2 -0.5 -1.7 -1.4 -1.2 -1.1 -0.8 -0.8 -1.4 -1.0 -1.2 -0.8 -0.9 -0.1 -0.8
Smoking status: Current 2.9 4.6 12.3 3.2 -2.8 -2.9 -0.5 -2.1 -2.7 -2.8 -1.4 -0.3 -2.4 -2.0 -2.7 -2.6 -1.9 -1.9 -1.6 -1.7 -2.7 -3.2 -2.5 -3.3 -2.8 -2.6 3.3 -2.8 -2.9 -0.8 1.2 3.5 -2.2 2.8 0.7 -0.2 -0.0 -1.4 -1.2 -0.3 -0.4 0.0 -1.5 -1.1 0.2 -1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 2.1 -0.9 0.9 0.7 0.2 0.8 0.8 0.1 0.4 0.0 1.5 0.4 0.8 0.8 0.8 0.6 0.5 0.5 0.9 1.3 0.9 0.9 0.3 0.6 -0.9 1.0 1.0 -0.4 -1.0 -0.7 0.7 -0.6 0.3 0.1 0.6 0.4 0.6 0.1 0.3 0.5 0.8 0.4 0.3 0.4
Whole body water mass 0.9 5.2 11.4 2.1 -2.6 -2.0 -2.5 -1.3 -2.4 -1.3 -2.7 -2.6 -0.9 -2.5 -2.4 -2.1 -2.9 -1.4 -2.0 -2.7 -2.5 -1.9 -2.3 -1.4 -1.4 -2.0 0.8 -0.5 -1.9 -2.0 -1.0 -1.3 -2.7 -1.8 -3.1 -2.5 -2.9 -2.7 -2.8 -3.3 -2.3 -3.4 -3.3 -3.1 0.3 -2.7
Leg predicted mass (right) 0.8 4.3 9.7 2.0 -2.5 -1.8 -2.2 -1.6 -2.2 -1.4 -2.4 -2.3 -1.1 -2.2 -2.2 -2.1 -2.5 -1.4 -2.0 -2.4 -2.3 -1.9 -2.1 -1.5 -1.4 -2.0 0.8 -0.4 -1.7 -1.8 -0.7 -1.0 -2.5 -1.4 -2.7 -2.2 -2.6 -2.4 -2.6 -2.7 -1.9 -3.1 -3.1 -2.8 -0.3 -2.4
Arm fat mass (left) 0.6 2.5 10.0 0.1 -0.7 0.2 -2.4 -0.1 -0.7 -0.1 -2.0 -2.4 -0.6 -1.3 -0.7 -0.6 -1.6 -0.1 -1.2 -1.8 -0.7 0.2 -0.5 0.1 -0.1 0.7 -1.5 1.1 0.5 -1.6 -1.1 -2.2 -1.2 -2.8 -3.2 -2.5 -2.6 -2.0 -2.0 -2.5 -2.3 -2.7 -1.7 -1.8 0.3 -2.1
Number of self-reported non-cancer illnesses 0.3 0.5 3.0 0.7 -0.4 -1.7 0.6 -0.7 -0.4 -0.4 0.3 0.9 1.2 -0.2 -0.4 -0.6 0.3 -0.4 -0.7 0.1 -0.4 -0.3 -0.5 -0.9 -0.3 -0.7 1.4 -0.6 -0.8 -0.7 -0.0 1.1 -0.1 1.3 0.9 0.7 0.5 0.3 -0.0 0.8 0.4 0.2 -0.0 -0.0 -0.5 0.3
Average weekly champagne plus white wine intake 0.2 0.2 1.5 0.5 -0.4 -0.7 0.6 -0.5 -0.4 -0.0 0.3 0.4 -0.7 -0.1 -0.3 -0.3 0.0 -0.5 -0.1 0.2 -0.4 -0.7 -0.2 -0.1 -0.1 -0.9 0.6 -0.7 -0.7 0.1 1.2 0.7 -0.1 0.9 0.5 0.5 0.4 0.3 0.3 0.3 0.5 0.3 -0.1 0.0 0.4 0.3
Miserableness 0.7 1.3 5.9 1.5 -1.2 -2.1 0.6 -1.1 -1.1 -1.6 0.0 0.6 0.5 -0.6 -1.1 -1.2 0.1 -0.7 -0.9 -0.2 -1.1 -1.3 -1.1 -1.8 -1.4 -1.9 2.0 -2.4 -1.6 -0.7 -0.2 1.9 -0.6 1.6 0.9 0.7 0.4 0.0 0.1 0.3 0.5 0.6 -0.5 0.1 -1.1 0.1
Guilty feelings 1.2 1.9 8.0 0.1 -0.7 -0.6 -1.7 -0.8 -0.8 -0.3 -1.7 -2.2 0.2 -1.6 -0.7 -0.8 -1.2 -0.1 -1.3 -1.6 -0.8 0.3 -0.5 -0.5 -0.3 -0.5 -0.5 0.7 -0.1 -1.7 -2.0 -1.6 -1.1 -2.1 -2.4 -2.2 -1.9 -1.7 -1.2 -2.8 -1.6 -1.8 -1.6 -1.4 1.1 -1.7
Wears glasses or contact lenses 0.9 1.0 3.0 -1.1 1.1 0.2 0.9 0.9 1.2 0.5 1.0 0.6 1.3 1.1 1.3 1.2 0.8 1.3 1.1 1.1 1.2 1.1 1.3 0.8 0.5 1.0 -0.7 1.7 0.8 0.7 0.9 0.1 1.0 0.2 1.0 0.7 1.0 1.0 1.1 1.0 0.7 1.4 1.6 1.3 -0.0 1.0
Ever taken oral contraceptive pill 0.3 0.3 2.0 -0.4 0.4 -0.1 -0.6 -0.1 0.3 0.1 -0.3 -0.8 -0.0 -0.1 0.4 0.1 0.0 -0.5 -0.1 -0.2 0.3 1.0 -0.1 0.3 -0.1 0.1 -1.0 0.4 0.4 -0.2 -1.3 -1.3 -0.2 -1.4 -1.1 -0.7 -0.8 -0.3 -0.2 -0.5 -0.4 -0.3 -0.2 -0.0 -0.5 -0.3
Hearing aid user 1.1 1.2 4.6 0.3 0.8 0.2 1.8 1.0 0.5 0.9 1.5 1.4 -0.1 1.3 0.7 0.6 1.3 1.4 0.7 1.3 0.5 -0.3 0.2 0.2 1.1 -0.4 0.8 0.8 0.5 0.3 0.4 1.0 1.0 1.3 1.7 1.8 1.6 1.5 1.4 1.2 2.1 1.3 0.4 1.3 -0.9 1.6
Mother’s age at death 0.5 0.6 2.7 -1.0 0.6 1.5 -0.4 1.3 0.7 0.8 0.1 -0.2 0.3 0.0 0.8 1.0 0.4 0.7 1.0 0.3 0.8 0.7 0.5 1.1 0.8 1.4 -1.1 -0.9 1.6 1.6 -0.1 -0.6 0.5 -0.6 -0.3 -0.3 -0.2 0.1 0.0 0.4 -0.6 -0.1 0.5 0.1 0.1 0.1
Financial situation satisfaction 1.0 1.3 4.8 0.2 -0.5 -0.1 -1.3 -0.3 -0.5 -0.4 -1.3 -1.5 0.4 -1.1 -0.5 -0.5 -1.3 -0.7 -1.0 -1.1 -0.6 0.4 -0.2 0.2 -0.5 -0.4 -0.6 1.3 0.3 -1.3 -2.2 -1.5 -1.0 -1.9 -2.0 -1.6 -1.7 -1.3 -1.3 -1.6 -1.2 -1.6 -1.4 -1.2 -0.5 -1.3
Tinnitus: Yes, now most or all of the time 1.2 1.4 2.8 0.8 -1.1 -1.3 -1.5 -0.9 -1.2 -0.6 -1.6 -1.6 -0.6 -1.3 -1.1 -1.1 -1.6 -0.6 -1.0 -1.4 -1.1 -0.6 -1.1 -0.9 -0.6 -0.8 -0.1 -1.0 -0.7 -1.0 -0.9 -0.5 -1.2 -0.9 -1.6 -1.6 -1.6 -1.5 -1.3 -1.7 -1.2 -1.5 -1.6 -1.3 0.1 -1.5
Commuting to job workplace: Public transport 0.8 0.9 7.0 1.0 -0.8 -0.3 0.5 -0.2 -0.8 -1.0 0.1 0.5 -0.4 -0.3 -0.8 -0.6 0.0 -1.0 -0.3 -0.1 -0.9 -1.1 -1.1 -0.8 -1.1 -1.9 1.4 -2.6 -1.5 0.9 0.9 1.7 -0.3 1.6 1.1 0.6 0.9 0.1 0.5 -0.3 0.9 0.7 -0.2 0.0 1.5 0.2
Eye problems/disorders: Glaucoma 1.8 2.1 5.1 1.4 -1.7 -0.5 -1.6 -1.0 -1.7 -2.1 -1.8 -1.6 -0.3 -2.1 -1.7 -1.6 -1.8 -1.9 -1.1 -1.8 -1.7 -1.2 -1.4 -2.0 -2.3 -1.0 1.0 -0.9 -1.5 -1.4 -0.9 0.9 -1.8 0.3 -1.0 -1.5 -1.4 -1.8 -1.6 -0.7 -1.4 -0.9 -1.2 -1.4 -0.5 -1.8
Medication: Blood pressure 1.1 2.0 7.2 2.0 -1.6 -0.7 -0.2 -1.5 -1.7 -2.0 -0.7 -0.1 -0.6 -1.0 -1.7 -1.7 -0.9 -2.3 -2.1 -1.0 -1.7 -1.3 -1.4 -1.6 -2.1 -2.4 2.3 -1.8 -1.8 -1.8 0.1 1.7 -1.2 1.3 -0.3 0.0 -0.8 -0.7 -0.7 0.2 -0.1 -0.2 -1.5 -0.5 -2.7 -0.7
Pain type(s) experienced in last month: Hip pain 0.2 0.2 1.8 0.4 -0.3 0.8 0.4 0.5 -0.2 -0.2 0.2 0.5 -1.4 0.2 -0.3 -0.1 0.1 0.6 -0.1 0.1 -0.3 -0.7 -0.1 0.1 -0.1 -0.5 1.0 -1.1 -0.4 0.7 0.1 0.7 -0.0 0.7 0.5 0.6 0.4 0.3 0.1 0.3 0.2 0.1 -0.0 -0.1 0.2 0.2
Supplements: Fish oil (including cod liver oil) 0.4 0.6 1.7 0.8 -1.0 0.7 -0.7 -0.8 -0.9 -0.7 -0.8 -0.8 -0.8 -0.9 -0.8 -0.9 -0.7 -0.5 -0.9 -0.8 -0.9 -0.8 -1.3 -1.0 -0.8 -0.5 0.6 -0.5 -0.6 -0.4 -0.7 0.4 -0.7 0.2 -0.9 -0.6 -0.9 -0.8 -0.7 -0.4 -0.7 -0.6 -0.8 -0.5 -0.4 -0.8
High cholesterol (Self-reported) 2.8 4.9 10.0 -1.4 2.2 -0.4 3.0 1.7 2.1 2.0 3.0 3.1 2.7 2.4 2.2 2.0 2.5 1.3 1.5 2.9 2.1 1.9 2.4 1.6 1.9 1.1 0.1 1.0 1.3 1.2 2.2 0.7 2.6 1.4 2.5 3.0 2.6 3.0 2.6 3.2 2.9 2.6 2.4 2.9 -1.1 3.0
Medication: Bendroflumethiazide 0.2 0.3 1.9 -0.4 0.5 1.0 -0.5 0.0 0.3 -0.1 -0.3 -0.6 -0.3 0.0 0.3 0.2 -0.2 0.2 0.1 -0.2 0.3 1.0 0.6 0.3 -0.3 0.8 -1.0 1.1 0.5 -0.9 -1.1 -0.6 0.0 -0.7 -0.9 -0.5 -0.9 -0.3 -0.3 0.4 -0.6 -0.1 0.2 0.2 -1.4 -0.3
Medication: Paracetamol 0.3 0.5 2.0 -0.0 0.4 0.3 1.0 0.6 0.3 0.2 0.9 0.8 1.0 0.6 0.3 0.4 1.2 1.2 0.4 0.8 0.3 -0.2 0.5 0.1 0.3 -0.6 0.7 -0.5 0.1 0.4 1.4 0.5 0.8 0.3 0.6 1.0 1.0 0.9 0.9 -0.2 1.4 0.5 0.1 0.7 0.3 0.9
Medication: Lisinopril 0.1 0.2 1.0 0.1 0.2 0.1 0.4 -0.3 0.1 -0.6 0.4 0.4 0.2 0.1 0.1 -0.1 0.3 -0.2 -0.1 0.3 0.1 0.2 0.1 -0.3 -0.6 -0.3 0.2 -0.0 0.1 -0.4 -0.0 1.0 0.2 0.4 0.5 0.5 0.6 0.4 0.5 0.1 0.9 0.8 0.3 0.8 0.1 0.3
Medication: Atorvastatin 2.4 2.9 5.6 -1.7 2.2 0.2 1.6 1.9 2.1 1.9 1.9 1.5 1.1 2.0 2.2 2.1 2.1 2.4 1.8 2.0 2.1 2.0 1.9 1.9 1.8 1.4 -1.0 1.8 1.6 1.2 0.4 -0.8 2.0 -0.2 1.0 1.4 1.5 1.9 1.8 1.8 1.6 1.6 2.0 2.0 0.2 1.9
Illnesses of father: High blood pressure 0.3 0.4 1.8 0.6 -0.5 0.2 0.0 -1.3 -0.5 -0.6 -0.2 0.1 -0.9 -0.3 -0.5 -0.9 -0.5 -1.3 -1.0 -0.3 -0.5 -0.7 -0.5 -0.9 -0.7 -0.6 0.5 -0.9 -1.0 -0.4 1.0 0.2 -0.3 0.4 -0.1 0.1 -0.3 -0.2 -0.4 0.2 -0.3 -0.2 -0.4 -0.2 -0.8 -0.2
Alcohol drinker status: Never 0.1 0.1 0.9 -0.4 0.3 -0.0 0.0 0.4 0.3 0.2 0.0 -0.0 -0.9 0.4 0.3 0.3 -0.2 0.6 0.5 0.1 0.3 0.6 0.3 0.3 0.1 0.7 -0.1 -0.2 0.0 -0.4 -0.5 -0.5 0.1 -0.2 0.1 0.0 -0.2 0.1 -0.2 0.4 -0.6 -0.2 0.3 -0.1 -0.8 0.1
Ever smoked 0.4 0.6 3.6 0.9 -0.8 -1.9 -0.1 -0.9 -0.7 -0.9 -0.3 -0.1 -1.2 -0.6 -0.7 -0.9 -0.6 -1.0 -0.3 -0.5 -0.8 -1.4 -0.8 -1.2 -1.1 -0.8 0.7 -0.9 -1.1 0.1 0.1 0.7 -0.7 0.7 -0.0 0.0 -0.5 -0.3 -0.6 0.6 -0.2 -0.1 -0.5 -0.3 -1.6 -0.3
Basal metabolic rate 0.8 4.5 11.2 1.7 -2.2 -1.6 -2.6 -1.1 -2.0 -1.0 -2.6 -2.6 -0.9 -2.3 -2.0 -1.8 -2.7 -1.1 -1.9 -2.5 -2.1 -1.4 -1.9 -1.1 -1.1 -1.5 0.3 -0.2 -1.4 -2.0 -1.0 -1.6 -2.4 -2.1 -3.2 -2.6 -2.9 -2.6 -2.7 -3.2 -2.4 -3.3 -3.1 -2.9 0.4 -2.6
Leg fat percentage (left) 0.4 1.6 6.3 -0.8 0.2 1.2 -1.9 0.4 0.2 0.5 -1.3 -1.7 -0.4 -0.6 0.1 0.1 -0.9 0.5 -0.4 -1.0 0.2 1.1 0.4 0.5 0.6 1.6 -2.0 1.3 1.3 -1.1 -1.0 -2.2 -0.4 -2.5 -2.3 -1.9 -1.8 -1.2 -1.3 -1.6 -1.9 -1.9 -0.6 -1.1 0.5 -1.3
Arm fat-free mass (left) 0.8 4.1 10.0 1.6 -2.1 -1.8 -2.4 -0.9 -2.0 -0.9 -2.5 -2.4 -0.8 -2.2 -2.0 -1.7 -2.6 -1.2 -1.7 -2.4 -2.1 -1.6 -1.7 -1.1 -1.0 -1.5 0.4 -0.5 -1.5 -1.9 -0.6 -1.4 -2.3 -1.9 -3.0 -2.4 -2.7 -2.5 -2.5 -3.2 -2.3 -3.2 -2.9 -2.8 0.7 -2.5
Number of operations (self-reported) 0.5 0.8 3.5 -0.7 0.2 0.5 -1.1 0.0 0.2 0.0 -0.7 -1.2 1.9 -0.7 0.3 0.1 -0.4 -0.3 -1.0 -0.5 0.2 1.2 0.2 0.8 0.1 0.5 -1.1 0.4 1.0 -0.7 -1.9 -1.5 -0.2 -1.6 -1.3 -1.2 -1.1 -0.7 -0.6 -0.9 -1.2 -0.9 -0.2 -0.6 0.1 -0.7
Average weekly beer plus cider intake 2.7 3.8 8.6 2.4 -2.4 -2.2 -1.4 -2.4 -2.4 -2.4 -1.8 -0.9 -2.3 -2.0 -2.4 -2.6 -2.2 -1.9 -2.0 -1.9 -2.4 -2.3 -2.4 -2.9 -2.4 -1.9 2.1 -1.1 -2.6 -1.7 -1.3 1.5 -2.4 1.1 -0.5 -1.0 -1.4 -1.8 -2.0 -0.7 -1.5 -1.4 -1.9 -2.0 -0.9 -1.7
Irritability 0.6 1.0 4.4 1.2 -1.1 -1.2 0.6 -0.8 -1.0 -0.8 0.1 0.7 0.4 -0.2 -0.9 -0.9 -0.3 -0.3 -0.4 -0.1 -1.0 -1.5 -0.8 -1.4 -0.9 -1.8 2.1 -1.8 -1.3 -0.6 0.8 1.8 -0.5 1.8 1.0 0.9 0.3 0.2 0.0 0.7 0.6 0.3 -0.5 -0.1 -1.2 0.2
Risk taking 1.9 2.8 8.8 2.5 -2.0 -0.8 -0.6 -1.4 -2.1 -1.8 -1.0 -0.4 -2.6 -1.2 -2.1 -2.0 -1.5 -1.7 -1.4 -1.3 -2.1 -2.9 -2.1 -2.1 -1.6 -2.8 2.1 -1.4 -3.0 -0.4 0.0 1.2 -1.7 1.0 -0.3 -0.3 -0.8 -1.1 -1.3 -0.9 -0.1 -1.1 -2.2 -1.3 -2.0 -1.0
Ever had prostate specific antigen (PSA) test 0.2 0.2 1.9 -0.1 0.0 0.2 -0.4 0.6 0.0 0.1 -0.3 -0.5 -1.3 -0.0 -0.0 0.3 -0.4 0.4 0.1 -0.3 -0.0 0.3 0.2 0.6 0.3 0.1 -0.6 -0.1 -0.1 -0.1 -1.4 -0.8 -0.2 -0.6 -0.5 -0.5 -0.5 -0.4 -0.4 -0.5 -0.6 -0.6 -0.2 -0.4 0.0 -0.4
Fractured/broken bones in last 5 years 0.8 1.0 6.9 1.0 -1.1 -2.6 -0.4 -1.3 -1.1 -1.3 -0.6 -0.3 0.9 -0.8 -1.1 -1.3 -0.8 -0.8 -1.6 -0.7 -1.1 -0.9 -0.8 -0.9 -1.3 -1.2 1.3 -1.5 -1.4 -1.5 0.1 1.0 -1.0 0.8 0.1 -0.2 -0.2 -0.6 -0.6 -0.4 -0.6 -0.3 -0.5 -0.9 0.3 -0.5
Age started oral contraceptive pill 1.4 1.8 4.7 -1.3 1.3 0.5 1.3 1.2 1.4 1.2 1.5 1.5 2.0 1.3 1.4 1.3 1.9 1.1 1.3 1.6 1.4 1.0 1.0 1.1 1.0 0.8 -0.2 -0.9 1.3 2.2 0.4 0.4 1.6 0.6 1.4 1.4 1.6 1.6 1.6 1.3 1.2 1.7 1.8 1.7 0.9 1.6
Diastolic blood pressure, automated reading 0.3 1.0 4.8 1.1 -0.3 -0.9 1.1 -0.2 -0.5 -0.4 0.8 1.2 0.6 0.3 -0.4 -0.5 0.2 -0.7 -0.2 0.5 -0.5 -1.1 -0.2 -1.4 -0.3 -1.4 2.2 -0.8 -1.1 -0.5 1.8 1.9 0.2 1.6 1.1 1.4 0.7 0.8 0.7 1.0 1.4 1.0 -0.3 0.9 -1.6 0.8
Ever depressed for a whole week 0.2 0.3 3.9 -0.1 0.0 0.6 0.6 1.3 0.1 0.3 0.4 0.6 -0.1 0.3 0.1 0.6 0.3 -0.2 0.7 0.4 0.1 0.2 0.1 0.4 0.4 -0.4 0.6 -1.6 0.3 0.5 -0.1 -0.1 0.3 0.1 0.1 0.5 -0.1 0.4 0.0 0.7 0.1 -0.2 -0.2 -0.0 -2.0 0.4
Unable to work because of sickness or disability 0.3 0.3 3.1 0.5 -0.6 -0.2 -0.4 0.0 -0.6 -0.7 -0.6 -0.4 -0.1 -0.5 -0.6 -0.4 -0.5 -0.4 -0.3 -0.6 -0.6 -0.4 -0.6 -0.6 -0.7 -0.6 0.5 -0.4 -0.2 0.0 -0.2 0.0 -0.6 -0.3 -0.9 -0.5 -1.0 -0.6 -0.7 -0.1 -0.5 -0.6 -0.9 -0.3 -1.8 -0.6
Commuting to job workplace: Cycle 0.5 0.6 1.4 0.5 -0.9 -0.1 -1.2 -0.6 -0.8 -0.4 -1.1 -1.1 0.8 -1.0 -0.8 -0.7 -0.9 -0.5 -0.5 -1.1 -0.8 -0.4 -0.8 -0.8 -0.4 -0.3 0.0 0.3 -0.3 -0.2 -0.5 -0.2 -0.8 -0.2 -0.7 -1.1 -0.7 -1.1 -0.8 -1.0 -0.6 -0.8 -0.9 -0.9 0.5 -1.1
Myopia 1.3 1.9 10.3 -0.7 0.2 -0.4 -1.6 0.1 0.2 0.1 -1.2 -2.1 0.7 -0.6 0.2 0.1 -0.6 0.5 -1.2 -1.0 0.2 1.6 0.3 1.2 -0.0 0.0 -2.0 1.8 0.8 -0.9 -1.7 -3.0 -0.5 -3.2 -2.6 -2.0 -1.9 -1.2 -1.2 -2.2 -1.3 -1.9 -1.1 -1.2 -0.1 -1.2
Vascular/heart problems diagnosed by doctor 0.9 2.3 6.5 -2.0 1.3 2.5 0.2 2.2 1.7 2.5 0.6 0.2 0.1 1.1 1.6 2.1 1.2 1.6 2.2 0.9 1.7 1.4 1.3 2.3 2.5 2.4 -2.2 0.7 2.2 2.3 0.2 -1.9 1.4 -1.4 -0.2 -0.1 0.6 0.6 0.8 -0.3 0.0 0.0 1.1 0.5 2.4 0.6
Cholesterol lowering medication 1.0 1.5 4.6 -0.1 0.7 -0.5 1.8 0.9 0.7 0.6 1.6 2.0 2.1 1.2 0.7 0.8 1.5 0.5 0.4 1.4 0.7 0.6 0.9 0.6 0.7 -0.3 1.0 -0.1 0.4 0.5 1.5 1.3 1.2 1.5 1.9 1.9 2.0 1.6 1.6 1.3 1.9 1.7 1.0 1.4 0.5 1.6
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 3.6 0.3 -0.7 -0.4 -1.3 -0.5 -0.8 -1.0 -1.2 -1.3 -0.4 -1.0 -0.8 -0.7 -1.0 -0.7 -0.5 -1.1 -0.8 -0.4 -1.0 -0.6 -0.8 -0.1 0.0 -1.1 -0.3 -0.9 -1.9 -0.4 -1.1 -0.7 -1.1 -1.3 -1.3 -1.2 -1.3 -1.0 -1.4 -1.3 -0.8 -1.3 -0.2 -1.2
Pain experienced in last month 0.8 1.3 4.1 -1.5 1.4 0.8 0.4 0.9 1.5 1.5 0.8 0.4 2.0 1.1 1.4 1.3 1.1 0.1 1.1 1.0 1.5 1.5 1.4 1.7 1.4 1.1 -1.8 1.3 1.3 1.2 0.3 -1.8 1.2 -1.2 -0.1 0.2 0.2 0.9 0.8 0.6 0.6 0.5 0.8 1.0 -0.7 0.8
Supplements: Calcium 3.7 4.1 7.3 2.4 -2.6 -1.8 -1.7 -2.4 -2.5 -2.5 -2.0 -1.4 -0.4 -2.5 -2.5 -2.6 -1.9 -2.2 -2.7 -2.2 -2.6 -2.0 -2.4 -2.4 -2.4 -2.6 2.4 -1.6 -2.3 -1.3 -1.3 1.3 -2.4 0.6 -0.9 -1.4 -1.5 -2.1 -2.0 -1.8 -1.3 -1.6 -2.3 -2.1 -0.3 -2.0
Basal cell carcinoma (self-reported) 0.7 0.8 2.5 1.3 -1.2 -0.6 -0.4 -0.9 -1.2 -0.9 -0.7 -0.3 -1.6 -0.8 -1.1 -1.1 -1.1 -0.5 -1.1 -0.8 -1.3 -1.4 -0.9 -1.0 -0.8 -1.5 1.6 -0.7 -0.9 -0.6 -0.0 0.7 -0.9 0.4 -0.2 -0.3 -0.4 -0.7 -0.8 -0.7 -0.2 -0.8 -1.4 -0.9 -0.4 -0.7
Heart attack/myocardial infarction (self-reported) 0.4 0.6 2.2 0.8 -0.5 -1.4 -0.5 -1.1 -0.7 -1.1 -0.6 -0.4 -0.9 -0.8 -0.6 -0.8 -0.8 -0.3 -0.4 -0.7 -0.6 -0.7 -0.9 -1.3 -1.3 0.1 0.4 0.6 -0.7 -1.2 -1.5 1.2 -0.8 0.9 0.2 -0.2 -0.2 -0.6 -0.7 0.5 -0.5 0.1 -0.0 -0.3 0.2 -0.6
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 2.0 -0.6 0.4 0.9 -0.8 -0.2 0.3 0.4 -0.5 -0.9 0.9 -0.5 0.3 0.1 -0.2 -0.4 -0.1 -0.4 0.3 0.8 0.4 0.1 0.3 1.0 -0.9 1.4 0.5 -0.6 -0.4 -0.7 0.1 -1.0 -1.0 -1.0 -0.6 -0.5 0.0 -0.8 -0.6 -0.1 0.0 0.2 1.1 -0.5
Heart disease (siblings) 0.3 0.4 1.7 0.3 -0.3 -0.8 -1.1 -0.9 -0.3 -0.7 -0.8 -1.0 0.2 -0.6 -0.2 -0.6 -0.5 0.3 -0.5 -0.7 -0.3 -0.0 -0.3 -0.8 -0.7 0.2 -0.5 0.1 -0.2 -0.4 -1.3 -0.2 -0.6 -0.6 -0.7 -1.0 -0.4 -0.8 -0.6 -1.0 -0.6 -0.4 -0.4 -0.4 0.7 -0.8
Alcohol drinker status: Previous 0.9 1.0 4.0 -1.6 1.3 1.9 0.1 0.7 1.3 0.8 0.5 0.1 -0.7 1.0 1.3 1.1 0.6 1.1 1.1 0.7 1.3 1.6 1.1 1.3 0.6 2.0 -1.5 0.9 1.6 0.4 -0.9 -1.1 1.0 -1.0 -0.4 -0.0 -0.0 0.5 0.5 0.5 -0.3 0.3 1.1 0.8 -0.0 0.4
Pack years of smoking 0.4 0.6 2.3 0.7 -0.1 -0.3 1.1 0.3 -0.1 -0.1 0.8 1.3 -1.3 0.3 -0.1 -0.0 0.4 -0.6 0.8 0.6 -0.1 -0.9 -0.3 -0.4 -0.4 -0.1 1.1 -0.6 -0.2 1.0 0.8 1.5 0.2 1.5 1.0 1.2 0.8 0.8 0.4 1.5 0.8 0.8 0.4 0.7 -0.9 0.8
Impedance of whole body 2.6 13.4 26.5 -3.0 3.9 2.5 4.3 2.7 3.8 3.0 4.5 4.4 1.9 4.1 3.7 3.5 4.5 2.7 3.6 4.5 3.8 2.8 3.9 2.5 3.0 2.5 -0.2 1.6 2.7 3.2 2.6 1.7 4.3 2.5 4.6 4.3 4.6 4.5 4.6 4.8 4.1 5.2 4.9 4.9 0.3 4.5
Leg fat mass (left) 0.5 1.9 7.4 -0.1 -0.5 0.2 -2.1 0.1 -0.4 0.1 -1.7 -2.0 -0.5 -1.1 -0.4 -0.4 -1.4 0.1 -0.8 -1.5 -0.4 0.4 -0.2 0.1 0.2 0.7 -1.4 0.8 0.7 -1.3 -0.8 -2.1 -1.0 -2.6 -2.7 -2.2 -2.2 -1.6 -1.7 -2.2 -2.1 -2.4 -1.4 -1.7 0.4 -1.7
Arm predicted mass (left) 1.0 5.0 11.2 1.9 -2.4 -2.0 -2.5 -1.2 -2.3 -1.2 -2.7 -2.6 -0.9 -2.5 -2.2 -2.0 -2.8 -1.4 -2.0 -2.7 -2.3 -1.8 -2.0 -1.3 -1.2 -1.8 0.6 -0.5 -1.7 -2.1 -0.9 -1.4 -2.6 -1.9 -3.2 -2.6 -2.9 -2.7 -2.7 -3.4 -2.4 -3.4 -3.2 -3.0 0.7 -2.7