[Hub]/) : Traits : Waist circumference : ← →

chr7:73,425,238-77,744,459

Best TWAS P=6.25e-17 · Best GWAS P=2.42e-16 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DTX2P1-UPK3BP1-PMS2P11	0.18	0.09	enet	21	0.12	6.1e-15	5.2	6.7	2.8e-11	-0.10	0.00	1.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	POM121C	0.08	0.05	lasso	2	0.04	1.1e-05	-8.2	-8.1	6.8e-16	0.99	0.00	1.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	STAG3L1	0.23	0.14	enet	13	0.17	1.0e-19	-8.2	-7.5	9.5e-14	0.91	0.00	1.00	FALSE
4	GTEx	Adipose Subcutaneous	PMS2P3	0.15	0.12	lasso	3	0.10	9.8e-09	-7.1	-7.4	1.8e-13	0.96	0.00	1.00	FALSE
5	GTEx	Adipose Subcutaneous	POM121C	0.20	0.11	enet	18	0.12	1.2e-09	-8.2	-6.6	4.8e-11	0.80	0.00	1.00	FALSE
6	GTEx	Adipose Subcutaneous	TRIM73	0.20	0.12	enet	26	0.12	2.0e-10	-8.2	-6.5	6.7e-11	0.82	0.00	1.00	FALSE
7	GTEx	Adipose Subcutaneous	STAG3L1	0.30	0.24	enet	24	0.27	2.4e-22	-8.2	-7.7	1.7e-14	0.92	0.00	1.00	FALSE
8	GTEx	Adipose Visceral Omentum	POM121C	0.16	0.10	lasso	5	0.12	7.2e-07	5.1	-6.4	1.3e-10	0.80	0.02	0.98	FALSE
9	GTEx	Adipose Visceral Omentum	TRIM73	0.17	0.19	lasso	3	0.22	1.4e-11	-7.1	-6.2	5.0e-10	0.92	0.00	1.00	FALSE
10	GTEx	Adipose Visceral Omentum	STAG3L1	0.20	0.19	lasso	3	0.17	2.3e-09	-8.2	-8.1	5.4e-16	1.00	0.00	1.00	FALSE
11	GTEx	Artery Aorta	GSAP	0.19	0.07	lasso	2	0.04	2.8e-03	5.0	-5.4	6.8e-08	-0.01	0.06	0.79	TRUE
12	GTEx	Artery Aorta	STAG3L1	0.18	0.03	lasso	4	0.08	3.9e-05	-8.2	-8.1	6.8e-16	1.00	0.00	1.00	FALSE
13	GTEx	Artery Coronary	PMS2P5	0.15	-0.01	enet	13	0.08	1.4e-03	4.5	-5.2	1.7e-07	0.20	0.01	0.72	FALSE
14	GTEx	Artery Coronary	STAG3L1	0.28	0.13	lasso	4	0.17	1.8e-06	-7.2	-7.2	5.0e-13	0.86	0.01	0.99	FALSE
15	GTEx	Artery Tibial	POM121C	0.12	0.10	lasso	1	0.10	6.8e-08	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
16	GTEx	Artery Tibial	TRIM73	0.10	0.00	lasso	7	0.02	5.5e-03	-8.2	-5.5	4.4e-08	0.82	0.00	0.96	FALSE
17	GTEx	Artery Tibial	STAG3L1	0.25	0.19	lasso	4	0.19	8.3e-15	-8.2	-8.2	1.9e-16	1.00	0.00	1.00	FALSE
18	GTEx	Artery Tibial	FAM185BP	0.11	0.02	enet	22	0.02	1.1e-02	5.5	5.2	2.4e-07	-0.04	0.01	0.92	FALSE
19	GTEx	Brain Cerebellar Hemisphere	POM121C	0.33	0.32	lasso	3	0.30	1.4e-08	-8.2	-8.1	6.2e-16	1.00	0.00	1.00	FALSE
20	GTEx	Brain Cerebellar Hemisphere	TRIM73	0.35	0.28	enet	25	0.25	3.6e-07	-8.2	-6.2	7.7e-10	0.84	0.00	1.00	FALSE
21	GTEx	Brain Cerebellum	POM121C	0.30	0.15	lasso	8	0.08	2.4e-03	-8.2	-7.0	2.0e-12	0.90	0.00	0.97	FALSE
22	GTEx	Brain Cerebellum	GSAP	0.38	0.30	lasso	4	0.31	6.4e-10	5.2	-5.3	9.4e-08	-0.03	0.05	0.94	FALSE
23	GTEx	Brain Frontal Cortex BA9	POM121C	0.43	0.16	enet	24	0.17	3.4e-05	-8.2	-6.6	3.5e-11	0.81	0.00	0.98	FALSE
24	GTEx	Brain Frontal Cortex BA9	GSAP	0.38	0.22	lasso	6	0.21	3.0e-06	5.1	-5.8	6.5e-09	-0.01	0.05	0.71	TRUE
25	GTEx	Brain Hippocampus	PMS2P5	0.37	0.03	enet	12	0.05	2.9e-02	5.1	-5.5	4.1e-08	0.13	0.01	0.48	FALSE
26	GTEx	Brain Nucleus accumbens basal ganglia	PMS2P5	0.27	0.00	enet	20	0.03	6.6e-02	4.5	-5.2	1.8e-07	0.18	0.02	0.31	FALSE
27	GTEx	Brain Nucleus accumbens basal ganglia	POM121C	0.33	0.27	enet	11	0.25	2.7e-07	5.1	-5.4	5.6e-08	0.59	0.04	0.86	FALSE
28	GTEx	Brain Nucleus accumbens basal ganglia	TRIM73	0.34	0.16	enet	11	0.29	1.5e-08	5.1	-6.9	4.2e-12	0.82	0.00	1.00	FALSE
29	GTEx	Brain Nucleus accumbens basal ganglia	STAG3L1	0.29	0.09	enet	13	0.18	1.9e-05	-8.2	-7.0	3.0e-12	0.79	0.00	0.97	FALSE
30	GTEx	Brain Putamen basal ganglia	PMS2P3	0.37	0.13	lasso	6	0.18	6.0e-05	-7.2	-6.8	1.2e-11	0.73	0.01	0.85	FALSE
31	GTEx	Breast Mammary Tissue	PMS2P3	0.19	0.14	lasso	4	0.19	3.5e-10	-7.1	-7.4	1.2e-13	0.88	0.00	1.00	FALSE
32	GTEx	Breast Mammary Tissue	STAG3L1	0.16	0.15	lasso	2	0.14	8.7e-08	-8.2	-8.2	2.8e-16	0.98	0.00	1.00	FALSE
33	GTEx	Breast Mammary Tissue (Female)	PMS2P3	0.31	0.05	enet	8	0.10	6.2e-04	-7.2	-6.3	3.4e-10	0.69	0.02	0.79	FALSE
34	GTEx	Breast Mammary Tissue (Female)	POM121C	0.17	-0.01	lasso	3	0.02	6.3e-02	-8.2	-8.0	1.6e-15	0.90	0.01	0.63	FALSE
35	GTEx	Breast Mammary Tissue (Female)	STAG3L1	0.04	0.12	lasso	1	0.04	2.9e-02	-8.2	-8.2	2.4e-16	1.00	0.00	0.96	FALSE
36	GTEx	Cells EBV-transformed lymphocytes	STAG3L1	0.43	0.21	enet	21	0.23	3.8e-08	-8.2	-7.7	2.0e-14	0.86	0.00	1.00	FALSE
37	GTEx	Cells Transformed fibroblasts	PMS2P3	0.23	0.15	lasso	6	0.15	1.4e-11	-7.1	-7.2	4.3e-13	0.94	0.00	1.00	FALSE
38	GTEx	Cells Transformed fibroblasts	POM121C	0.15	0.06	lasso	5	0.07	1.2e-05	-8.2	-8.3	7.6e-17	0.99	0.00	1.00	FALSE
39	GTEx	Cells Transformed fibroblasts	STAG3L1	0.22	0.17	lasso	4	0.18	2.6e-13	-8.2	-8.1	4.2e-16	0.96	0.00	1.00	FALSE
40	GTEx	Colon Sigmoid	STAG3L1	0.30	0.18	lasso	4	0.18	8.5e-07	-8.2	-7.7	1.3e-14	0.97	0.00	1.00	FALSE
41	GTEx	Colon Transverse	STAG3L1	0.22	0.18	lasso	1	0.16	4.0e-08	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
42	GTEx	Esophagus Gastroesophageal Junction	STAG3L1	0.36	0.16	lasso	5	0.16	1.7e-06	-8.2	-7.3	2.7e-13	0.93	0.00	1.00	FALSE
43	GTEx	Esophagus Mucosa	PMS2P3	0.14	0.15	lasso	2	0.14	9.7e-10	-8.2	-8.4	6.3e-17	1.00	0.00	1.00	TRUE
44	GTEx	Esophagus Mucosa	POM121C	0.13	0.10	lasso	1	0.07	1.0e-05	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
45	GTEx	Esophagus Mucosa	STAG3L1	0.19	0.19	lasso	1	0.18	2.4e-12	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
46	GTEx	Esophagus Muscularis	STAG3L2	0.23	0.09	enet	33	0.15	1.9e-09	4.5	-5.5	3.2e-08	0.26	0.02	0.98	FALSE
47	GTEx	Esophagus Muscularis	TRIM73	0.12	0.07	lasso	2	0.05	3.5e-04	-7.1	-7.0	1.9e-12	0.96	0.00	0.98	FALSE
48	GTEx	Esophagus Muscularis	STAG3L1	0.30	0.15	lasso	4	0.16	4.3e-10	-8.2	-7.4	1.4e-13	0.94	0.00	1.00	FALSE
49	GTEx	Heart Atrial Appendage	STAG3L1	0.14	0.04	enet	12	0.04	5.0e-03	-7.1	-6.7	2.6e-11	0.76	0.00	0.95	FALSE
50	GTEx	Heart Left Ventricle	POM121C	0.13	0.12	lasso	1	0.09	2.2e-05	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
51	GTEx	Lung	POM121C	0.13	0.10	lasso	3	0.10	7.8e-08	-8.2	-8.1	8.4e-16	0.98	0.00	1.00	FALSE
52	GTEx	Lung	TRIM73	0.14	0.03	enet	8	0.06	2.9e-05	-7.1	-6.2	6.2e-10	0.79	0.00	0.99	FALSE
53	GTEx	Lung	STAG3L1	0.28	0.12	enet	35	0.16	3.3e-12	-8.2	-7.1	1.2e-12	0.79	0.00	1.00	FALSE
54	GTEx	Muscle Skeletal	PMS2P3	0.07	0.07	lasso	2	0.06	3.8e-06	-8.2	-8.2	2.7e-16	1.00	0.00	1.00	FALSE
55	GTEx	Muscle Skeletal	TRIM73	0.08	0.05	enet	11	0.06	3.4e-06	-8.2	-7.9	2.3e-15	0.88	0.00	1.00	FALSE
56	GTEx	Muscle Skeletal	STAG3L1	0.16	0.10	enet	24	0.10	3.7e-10	-8.2	-6.9	5.8e-12	0.85	0.00	1.00	FALSE
57	GTEx	Nerve Tibial	PMS2P5	0.16	0.04	enet	34	0.08	3.5e-06	4.5	-5.4	6.6e-08	0.22	0.02	0.96	FALSE
58	GTEx	Nerve Tibial	PMS2P3	0.29	0.13	enet	4	0.18	1.1e-12	-7.2	-6.7	1.9e-11	0.87	0.03	0.97	FALSE
59	GTEx	Nerve Tibial	POM121C	0.22	0.14	lasso	5	0.14	6.9e-10	-8.2	-8.2	2.2e-16	0.97	0.00	1.00	FALSE
60	GTEx	Nerve Tibial	STAG3L2	0.36	0.09	enet	13	0.24	9.5e-17	4.5	-5.8	5.2e-09	0.25	0.08	0.91	FALSE
61	GTEx	Nerve Tibial	TRIM73	0.19	0.20	enet	6	0.20	6.3e-14	-8.2	-7.0	3.4e-12	0.96	0.00	1.00	FALSE
62	GTEx	Nerve Tibial	STAG3L1	0.37	0.21	enet	34	0.22	1.2e-15	-8.2	-6.0	2.2e-09	0.83	0.00	1.00	FALSE
63	GTEx	Ovary	RHBDD2	0.55	0.00	enet	24	0.07	7.6e-03	-7.2	5.1	2.9e-07	-0.56	0.03	0.29	FALSE
64	GTEx	Skin Not Sun Exposed Suprapubic	PMS2P3	0.26	0.19	lasso	3	0.17	1.3e-09	-8.2	-8.0	9.8e-16	0.99	0.00	1.00	FALSE
65	GTEx	Skin Not Sun Exposed Suprapubic	STAG3L1	0.13	0.19	lasso	1	0.18	2.6e-10	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
66	GTEx	Skin Sun Exposed Lower leg	PMS2P3	0.38	0.30	lasso	3	0.29	1.9e-24	-8.2	-8.2	1.8e-16	1.00	0.00	1.00	FALSE
67	GTEx	Skin Sun Exposed Lower leg	STAG3L2	0.15	0.05	enet	8	0.08	2.8e-07	4.5	-5.4	6.8e-08	0.24	0.24	0.46	FALSE
68	GTEx	Skin Sun Exposed Lower leg	TRIM73	0.13	0.08	enet	10	0.14	1.6e-11	-7.1	-5.7	1.3e-08	0.85	0.01	0.99	FALSE
69	GTEx	Skin Sun Exposed Lower leg	STAG3L1	0.27	0.15	lasso	5	0.15	1.3e-12	-8.2	-8.2	1.9e-16	0.98	0.00	1.00	FALSE
70	GTEx	Stomach	PMS2P3	0.16	0.07	lasso	5	0.09	3.7e-05	-7.2	-7.4	1.7e-13	0.91	0.00	0.99	FALSE
71	GTEx	Stomach	TRIM73	0.23	0.09	lasso	5	0.09	3.2e-05	-8.2	-7.8	4.2e-15	0.96	0.00	0.99	FALSE
72	GTEx	Stomach	STAG3L1	0.35	0.20	lasso	5	0.18	4.2e-09	-7.2	-7.2	7.9e-13	0.86	0.01	0.99	FALSE
73	GTEx	Testis	TRIM73	0.20	0.21	lasso	2	0.19	6.2e-09	-8.2	-8.1	5.6e-16	1.00	0.00	1.00	FALSE
74	GTEx	Testis	STAG3L1	0.24	0.24	enet	14	0.27	1.4e-12	-8.2	-7.3	3.7e-13	0.88	0.00	1.00	FALSE
75	GTEx	Thyroid	POM121C	0.14	0.08	lasso	3	0.07	3.4e-06	-8.2	-8.2	3.2e-16	0.96	0.00	1.00	FALSE
76	GTEx	Thyroid	STAG3L2	0.26	0.13	enet	20	0.16	1.4e-12	4.5	-5.2	2.0e-07	0.24	0.77	0.22	FALSE
77	GTEx	Thyroid	GTF2IRD2B	0.03	0.04	lasso	1	0.03	1.9e-03	5.8	5.8	5.8e-09	-0.17	0.01	0.88	FALSE
78	GTEx	Thyroid	TRIM73	0.21	0.17	lasso	4	0.18	1.6e-13	-8.2	-7.3	3.3e-13	0.97	0.00	1.00	FALSE
79	GTEx	Thyroid	STAG3L1	0.36	0.24	enet	17	0.27	8.0e-21	-8.2	-7.5	5.6e-14	0.92	0.00	1.00	FALSE
80	GTEx	Whole Blood	STAG3L1	0.08	0.06	lasso	3	0.07	2.8e-07	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
81	METSIM	Adipose	NCF1	0.05	0.03	blup	130	0.04	3.9e-07	5.3	6.1	8.6e-10	-0.22	0.03	0.96	TRUE
82	METSIM	Adipose	POM121C	0.11	0.08	lasso	1	0.08	1.6e-11	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
83	METSIM	Adipose	TRIM73	0.11	0.11	lasso	5	0.12	8.6e-18	-7.1	-6.9	4.7e-12	0.95	0.01	0.99	FALSE
84	ROSMAP	Brain Pre-frontal Cortex	PMS2P3	0.05	0.04	lasso	1	0.03	4.6e-05	-8.2	-8.2	2.4e-16	1.00	0.00	1.00	FALSE
85	ROSMAP	Brain Pre-frontal Cortex	POM121C	0.36	0.26	lasso	7	0.27	2.8e-34	-8.2	-8.0	1.1e-15	0.99	0.00	1.00	FALSE
86	ROSMAP	Brain Pre-frontal Cortex	PMS2P2	0.17	0.08	enet	8	0.08	6.0e-10	-8.2	-7.3	2.1e-13	0.90	0.00	1.00	FALSE
87	ROSMAP	Brain Pre-frontal Cortex	GSAP	0.36	0.27	lasso	7	0.28	1.5e-35	5.1	-5.2	2.0e-07	-0.04	0.05	0.95	TRUE
88	ROSMAP	Brain Pre-frontal Cortex	STAG3L1	0.46	0.32	lasso	4	0.32	2.2e-42	-8.2	-8.2	2.8e-16	1.00	0.00	1.00	FALSE
89	ROSMAP	Brain Pre-frontal Cortex	GTF2IP1	0.09	0.06	lasso	3	0.05	1.7e-07	-8.2	-8.2	2.1e-16	1.00	0.00	1.00	FALSE
90	The Cancer Genome Atlas	Breast Invasive Carcinoma	POM121C	0.04	0.04	lasso	2	0.03	1.2e-07	-8.2	-8.2	2.9e-16	1.00	0.00	1.00	FALSE
91	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	POM121C	0.07	0.02	enet	3	0.04	5.8e-03	-8.2	-6.8	1.1e-11	0.85	0.00	0.67	FALSE
92	The Cancer Genome Atlas	Thyroid Carcinoma	POM121C	0.08	0.07	lasso	3	0.07	3.6e-07	-8.2	-8.3	1.3e-16	0.99	0.00	1.00	FALSE
93	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PMS2L3	0.23	0.14	lasso	2	0.14	1.3e-04	-8.2	-8.3	1.1e-16	0.98	0.00	0.92	FALSE