Hub : Genes

TMEM155

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0600 0.0240 0.0014 0.045 0.010 0.018 0.017 0.024 3.0e-06 0.021 0.0027 0.0033 0.00055
2 ROSMAP Brain Pre-frontal Cortex 0.0483 0.0204 0.0051 0.011 0.009 0.007 0.010 0.008 1.1e-02 0.024 0.0410 0.0170 0.02900

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.1 0.2 0.2 0.3 0.5
Bipolar Disorder or Schizophrenia 0.1 0.2 0.4 -0.7 0.2
Depressed Affect (Nagel 2018) 0.7 1.6 3.1 1.8 0.0
Depression (Nagel 2018) 1.0 1.4 2.8 1.7 0.2
Intelligence (Savage-Jansen 2018) 0.0 0.0 0.0 -0.2 0.2
Neuroticism (Nagel 2018) 0.3 0.8 1.6 1.3 -0.1
Schizophrenia (2018) 0.3 0.7 1.3 -1.1 -0.2
Schizophrenia vs Biploar Disorder 0.4 0.6 1.2 0.0 -1.1
Worry (Nagel 2018) 0.1 0.2 0.4 0.6 0.0
Alzheimer’s Disease (in mother) 0.1 0.2 0.3 0.1 -0.6
Alzheimer’s Disease (in father) 4.7 5.1 5.3 -2.2 -2.3
Alzheimer’s Disease (including proxy) 0.9 1.3 1.6 -1.0 -1.2
Crohns Disease (2017) 0.0 0.1 0.1 -0.1 0.4
Irritable Bowel Disease (IBD) 0.1 0.3 0.6 0.1 -0.8
Ulcerative Colitis (UC) 0.5 0.9 1.8 0.2 -1.3
Major Depression (MDD) 2.8 3.4 6.4 -0.6 -2.5
Reaction Time 0.3 0.5 1.0 -1.0 -0.1
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.3 -0.3 0.5
Breast Cancer 4.2 10.1 13.0 -2.7 -3.6
Ovarian Cancer 0.8 1.0 2.0 1.4 -0.1
Prostate Cancer 0.6 0.8 1.0 -1.0 -0.8
Age at First Birth 0.9 1.4 1.8 1.0 1.3
Bipolar Disorder (2011) 0.1 0.1 0.1 -0.4 0.2
Body Mass Index (BMI) (2010) 3.0 4.2 6.0 -2.5 -1.5
Coronary Artery Disease (CAD) 2.0 2.4 4.0 -2.0 -0.9
Crohns Disease (2012) 0.3 0.5 1.1 -1.0 -0.1
Mean Putamen Volume 0.0 0.0 0.0 -0.0 -0.0
Fasting Glucose 1.6 1.9 2.1 -1.3 -1.5
HbA1C 0.3 0.3 0.6 -0.7 -0.2
HDL Cholesterol 0.1 0.1 0.3 0.1 0.5
LDL Cholesterol 1.0 1.6 2.5 1.6 0.9
Lupus 2.7 4.1 5.4 -1.7 -2.3
Neuroticism (2016) 0.3 0.4 0.7 0.8 -0.3
Primary Biliary Cirrhosis 0.2 0.3 0.3 -0.5 -0.5
Rheumatoid Arthritis 0.0 0.1 0.1 0.4 0.0
Schizophrenia (2014) 0.3 0.6 1.2 -1.1 -0.3
Triglycerides 0.1 0.1 0.1 -0.3 0.4
Type 2 Diabetes (T2D) (2012) 1.5 1.7 3.0 -0.7 -1.7
Ulcerative Colitis 0.1 0.1 0.2 0.2 -0.5
Blood Eosinophil Count 0.5 4.1 7.3 2.7 1.0
Blood Platelet Count 1.4 16.4 23.8 -3.0 -4.9
Blood Red Count 3.2 30.7 30.8 -5.5 -5.5
Blood White Count 1.1 7.9 12.5 3.5 1.9
Heel T-Score 0.9 7.0 7.9 2.8 2.5
BMI 0.1 0.6 1.1 -1.1 -0.1
Height 4.5 85.8 116.6 -10.8 -7.4
Waist Hip Ratio (WHR) 0.7 3.3 6.6 2.6 0.2
Systolic Blood Pressure 0.7 3.7 4.6 -2.1 -1.7
Smoking Status 0.9 2.1 3.0 1.7 1.1
Allergy or Eczema 1.3 3.3 6.3 0.6 -2.5
Cardiovascular Disease 0.6 2.0 2.4 -1.6 -1.3
Hypothyroidism (self reported) 1.4 3.3 4.9 2.2 1.3
Respiratory disease 0.9 2.1 4.1 0.3 -2.0
Type 2 Diabetes (T2D) (2018) 0.8 1.4 2.8 -0.2 -1.7
Lung FEV1/FVC ratio 1.6 8.0 12.7 -3.6 -1.8
Lung FVC 0.4 2.3 2.9 1.7 1.3
Neuroticism 0.1 0.3 0.3 0.6 -0.5
Chronotype (morning person) 1.4 3.2 5.8 0.7 2.4
Hair Pigment 0.0 0.0 0.1 -0.2 0.0
Tanning 0.3 4.2 7.1 2.7 1.1
Hand grip strength (left) 0.5 1.3 1.8 0.9 1.4
Number of treatments/medications taken 0.1 0.1 0.3 0.5 0.1
Average weekly spirits intake 2.8 3.4 4.0 1.7 2.0
Sensitivity / hurt feelings 0.3 0.5 1.1 0.0 -1.0
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.3 0.3 -0.6
Hearing difficulty/problems: Yes 0.0 0.0 0.1 0.0 0.2
Relative age of first facial hair 0.3 0.5 0.8 -0.9 -0.5
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 0.8 -0.9 0.7
Ever used hormone-replacement therapy (HRT) 0.2 0.2 0.2 0.5 -0.4
Ever had hysterectomy (womb removed) 1.9 2.2 3.1 -1.8 -1.1
Systolic blood pressure, automated reading 0.7 2.1 3.3 -1.8 -1.0
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.2 -0.5 -0.1
Angina 0.2 0.3 0.5 0.7 -0.1
Medication for hormone replacement therapy 0.6 0.6 1.1 -1.0 -0.4
Vitamin and mineral supplements 0.1 0.2 0.2 -0.4 0.4
Supplements: Zinc 0.6 0.7 1.3 -0.2 -1.1
Medication: Co-codamol 0.1 0.1 0.2 0.1 -0.5
Medication: Metformin 0.1 0.1 0.1 -0.4 -0.3
Diabetes (father) 5.1 6.3 8.6 -2.0 -2.9
Diabetes (mother) 0.3 0.4 0.7 -0.4 -0.8
Severe depression (siblings) 0.6 0.7 0.8 0.7 0.9
Pack years adult smoking proportion 1.3 2.0 2.0 1.4 1.4
Impedance of leg (right) 0.6 3.1 5.6 2.4 0.7
Leg fat-free mass (left) 2.4 12.8 20.4 -4.5 -2.3
Trunk fat percentage 0.1 0.2 0.3 -0.4 0.5
Hand grip strength (right) 0.1 0.3 0.5 -0.3 0.7
Townsend deprivation index at recruitment 0.1 0.1 0.2 -0.5 -0.2
Current tobacco smoking 0.7 1.2 1.8 1.3 0.8
Average weekly fortified wine intake 1.2 1.4 2.6 1.6 0.5
Maternal smoking around birth 0.0 0.0 0.0 -0.1 -0.0
Fed-up feelings 0.2 0.4 0.5 0.5 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.2 0.5 0.3
Relative age voice broke 1.0 1.5 2.8 0.4 1.7
Taking other prescription medications 0.6 0.9 1.4 -0.6 -1.2
Age when periods started (menarche) 0.1 0.2 0.3 0.3 -0.6
Bilateral oophorectomy (both ovaries removed) 1.9 2.2 2.9 -1.2 -1.7
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.1 0.2 0.2 0.5
Tinnitus: Yes, but not now, but have in the past 0.7 0.8 1.4 0.3 -1.2
Qualifications: CSEs or equivalent 0.3 0.4 0.4 0.6 0.6
Serious illness, injury or assault to yourself 0.6 0.7 1.3 0.4 1.1
High blood pressure 4.1 11.5 12.6 -3.5 -3.2
Hayfever, allergic rhinitis or eczema 1.0 2.2 4.4 -0.2 -2.1
Multivitamins +/- minerals 0.6 0.7 1.4 -0.2 -1.2
Stomach or abdominal pain in last month 1.0 1.3 1.5 -1.1 -1.2
Supplements: Glucosamine 1.1 1.4 2.8 0.1 1.7
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 0.4 -0.2 0.7
Medication: Atenolol 0.9 1.1 2.0 -1.4 -0.6
Medication: Levothyroxine sodium 0.1 0.2 0.3 0.6 0.1
Sitting height 1.9 13.3 16.6 -4.1 -3.1
Chronic bronchitis/emphysema (father) 2.9 3.4 3.5 1.8 1.9
High blood pressure (mother) 5.2 7.3 7.4 -2.7 -2.7
Body mass index (BMI) 0.3 1.4 2.7 -1.7 0.2
Impedance of leg (left) 0.5 2.5 4.7 2.2 0.6
Leg predicted mass (left) 2.3 12.2 19.4 -4.4 -2.2
Trunk fat mass 0.4 1.8 3.6 -1.9 -0.3
Waist circumference 0.9 3.4 6.1 -2.5 -0.9
Number of incorrect matches in round 2.3 3.8 5.1 1.6 2.3
Past tobacco smoking 1.4 2.5 4.6 -2.1 -0.6
Alcohol usually taken with meals 0.2 0.4 0.7 -0.8 -0.2
Nervous feelings 0.1 0.1 0.2 0.3 -0.4
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 0.9 -0.5 -0.9
Hearing difficulty/problems with background noise 0.1 0.1 0.2 -0.2 -0.4
Hair/balding pattern: Pattern 2 1.1 1.4 1.5 1.2 1.1
Had menopause 0.0 0.0 0.1 -0.0 -0.2
Had other major operations 1.4 1.7 2.7 -1.6 -0.8
Forced vital capacity (FVC) 0.4 1.6 2.1 -1.4 -1.1
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.0 0.0 -0.0 0.1
Ever unenthusiastic/disinterested for a whole week 2.4 3.0 5.8 2.4 0.4
Qualifications: None of the above 0.2 0.4 0.6 0.8 -0.4
Financial difficulties in last 2 years 0.1 0.1 0.2 0.0 0.5
Mouth/teeth dental problems 0.9 1.4 2.5 -1.6 -0.5
Heart attack 4.9 6.3 8.2 2.9 2.1
Allergy 2.4 5.6 10.2 1.0 3.2
Pain all over the body in last month 0.5 0.6 0.7 0.9 -0.6
Diabetes (self-reported) 0.4 0.6 1.1 -0.2 -1.0
Hayfever/allergic rhinitis (self-reported) 5.1 6.8 10.0 -1.9 -3.2
Medication: Ramipril 0.7 0.9 1.6 -1.3 0.4
Medication: Simvastatin 0.0 0.1 0.1 0.0 -0.4
Fluid intelligence score 0.3 0.6 1.2 0.0 1.1
Illnesses of siblings 0.1 0.2 0.3 -0.2 0.5
Neuroticism score 0.2 0.4 0.8 0.9 -0.2
Weight 2.2 10.6 18.5 -4.3 -1.7
Impedance of arm (right) 0.8 3.5 5.7 2.4 1.2
Arm fat percentage (right) 0.2 0.9 1.2 -0.8 1.1
Trunk fat-free mass 4.3 24.5 38.1 -6.2 -3.3
Hip circumference 1.8 7.6 15.1 -3.9 -0.5
Time employed in main current job 2.4 2.7 3.2 -1.5 -1.8
Alcohol intake versus 10 years previously 1.9 2.8 3.0 -1.7 -1.6
Father’s age at death 0.1 0.2 0.2 -0.5 0.4
Worrier / anxious feelings 0.2 0.3 0.6 0.8 0.2
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.1 3.7 -0.7 -1.9
Falls in the last year 0.1 0.1 0.2 -0.3 0.4
Hair/balding pattern: Pattern 3 0.5 0.7 0.7 0.9 0.8
Number of live births 0.4 0.6 0.8 0.9 0.6
Forced expiratory volume in 1-second (FEV1) 0.8 2.8 3.0 -1.7 -1.6
Pulse rate 0.9 1.5 1.9 1.4 1.0
Happiness 0.3 0.4 0.5 -0.7 -0.5
Noisy workplace 2.5 3.0 3.0 1.7 1.7
Qualifications: A levels/AS levels or equivalent 0.1 0.2 0.3 0.3 0.6
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.2 -0.4 0.4
Mouth/teeth dental problems: Dentures 0.7 1.2 1.9 1.4 0.7
Asthma 1.3 2.5 4.5 -0.6 -2.1
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 1.7 1.1 1.3
Medication: Cholesterol lowering 1.9 3.0 3.9 2.0 1.5
Depression (self-reported) 1.7 2.1 2.8 1.7 1.2
Medication: Lansoprazole 0.5 0.6 1.1 1.0 0.4
Prospective memory result 0.5 0.6 0.7 -0.8 -0.8
Lung cancer (father) 0.6 0.7 1.3 1.1 0.4
Illnesses of mother 3.0 3.8 4.6 1.7 2.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.4 4.4 6.9 -2.6 -1.4
Pulse wave Arterial Stiffness index 0.1 0.1 0.2 0.0 0.5
Impedance of arm (left) 1.3 5.9 9.3 3.0 1.6
Arm fat mass (right) 0.7 2.8 5.6 -2.4 -0.2
Trunk predicted mass 4.4 25.1 39.1 -6.2 -3.4
Standing height 2.8 28.0 37.2 -6.1 -4.3
Length of working week for main job 0.5 0.5 1.1 0.1 -1.0
Exposure to tobacco smoke at home 1.4 1.5 2.0 1.4 1.0
Breastfed as a baby 0.4 0.5 0.7 0.5 0.8
Tense / ‘highly strung’ 1.1 1.8 1.8 1.4 1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 1.0 1.9 1.4 -0.1
Hair/balding pattern: Pattern 4 0.2 0.6 0.8 0.9 -0.6
Birth weight of first child 1.7 3.1 3.9 -2.0 -1.6
Peak expiratory flow (PEF) 3.4 8.0 9.5 -2.5 -3.1
Pulse wave reflection index 0.1 0.2 0.3 0.6 -0.0
Ever highly irritable/argumentative for 2 days 0.2 0.2 0.2 -0.4 -0.5
Loud music exposure frequency 0.5 0.5 0.8 0.9 -0.5
Qualifications: O levels/GCSEs or equivalent 0.0 0.0 0.0 0.1 -0.1
Mouth/teeth dental problems: Bleeding gums 0.6 0.7 1.4 1.2 -0.2
Blood clot in the leg (DVT) 0.2 0.3 0.3 -0.6 -0.5
Medication: Paracetamol 2.4 4.0 4.4 2.1 1.9
Headache pain in last month 0.8 1.4 2.6 -1.6 -0.5
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.3 -0.5 -0.2
Glaucoma (self-reported) 1.2 1.4 2.7 -1.6 -0.4
Gout (self-reported) 0.5 0.6 0.8 0.9 0.6
Hypothyroidism/myxoedema (self-reported) 0.9 1.9 2.6 1.6 1.1
Medication: Amlodipine 0.4 0.5 1.0 1.0 -0.2
Medication: Ventolin 100micrograms inhaler 1.0 1.2 2.2 -0.6 -1.5
Birth weight 0.4 0.8 1.3 1.2 0.5
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.2 1.1 -0.2
High blood pressure (siblings) 0.6 0.9 1.6 -0.4 -1.3
Forced vital capacity (FVC), Best measure 0.9 3.4 5.1 -2.3 -1.3
Body fat percentage 0.1 0.6 0.9 -0.4 1.0
Leg fat percentage (right) 0.2 0.9 1.3 -1.1 0.7
Arm fat-free mass (right) 3.0 15.3 23.5 -4.8 -2.7
Exposure to tobacco smoke outside home 0.5 0.7 1.1 -0.5 -1.1
Comparative body size at age 10 0.6 1.6 2.2 1.5 0.9
Number of full brothers 0.2 0.3 0.6 0.2 -0.7
Worry too long after embarrassment 0.6 1.0 1.4 -0.8 -1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 2.1 2.7 5.4 2.3 0.1
Wheeze or whistling in the chest in last year 1.0 1.7 3.4 0.3 -1.8
Number of children fathered 1.4 1.6 3.1 -0.0 -1.8
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.1 2.2 0.1 -1.5
Age at first live birth 0.7 1.3 2.4 0.5 1.5
Pulse wave peak to peak time 0.6 0.7 1.1 -0.6 -1.0
Health satisfaction 1.6 2.0 2.5 -1.6 -1.3
Shortness of breath walking on level ground 0.3 0.3 0.4 -0.4 -0.7
Qualifications: College or University degree 0.2 0.8 1.4 -0.3 1.2
Eye problems/disorders: None of the above 0.5 0.6 0.8 -0.9 -0.6
Mouth/teeth dental problems: Loose teeth 1.9 2.3 2.9 1.7 1.3
Emphysema/chronic bronchitis 0.9 1.0 1.1 -0.9 -1.0
Medication for pain relief, constipation, heartburn 0.6 1.0 1.6 -1.3 -0.6
Neck or shoulder pain in last month 0.3 0.4 0.7 -0.0 0.9
Medication: Blood pressure 0.1 0.1 0.2 0.1 -0.4
Angina (self-reported) 0.3 0.4 0.9 0.9 0.1
Migraine (self-reported) 0.4 0.5 0.5 -0.6 0.7
Medication: Ibuprofen 0.5 0.6 0.7 0.7 0.8
Medication: Allopurinol 0.7 0.9 1.0 0.9 1.0
Medication: Omeprazole 0.5 0.6 0.7 -0.7 -0.8
Medication: Seretide 50 evohaler 0.3 0.3 0.5 -0.7 0.3
Mean time to correctly identify matches 0.2 0.5 0.9 -0.9 0.2
Heart disease (mother) 0.4 0.5 0.9 1.0 -0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.2 0.4 -0.6 -0.0
Whole body fat mass 0.5 2.2 4.4 -2.1 -0.1
Leg fat mass (right) 0.5 2.0 3.9 -2.0 0.2
Arm predicted mass (right) 3.3 17.0 26.6 -5.2 -2.7
Pulse rate, automated reading 1.8 5.8 8.4 2.9 1.8
Alcohol intake frequency. 0.2 0.4 0.7 -0.4 -0.8
Comparative height size at age 10 2.6 14.4 23.9 -4.9 -2.2
Number of full sisters 10.3 12.6 20.7 4.5 2.1
Suffer from ‘nerves’ 0.4 0.6 0.7 0.7 -0.8
Overall health rating 0.7 1.4 1.8 -1.0 -1.3
Chest pain or discomfort 0.1 0.2 0.4 0.1 -0.6
Had major operations 0.8 0.9 1.2 1.1 -0.8
Age at last live birth 1.0 1.4 2.5 0.5 1.6
Family relationship satisfaction 0.2 0.3 0.5 -0.3 -0.7
Leg pain on walking 0.1 0.1 0.2 -0.4 -0.3
Qualifications: NVQ or HND or HNC or equivalent 0.0 0.0 0.1 0.0 0.2
Commuting to job workplace: Car/motor vehicle 0.6 0.7 1.1 0.6 1.1
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 0.7 -0.8 0.5
Medication: Aspirin 0.4 0.5 0.8 0.3 -0.9
Supplements: Vitamin C 0.9 1.1 1.1 1.0 1.0
Knee pain experienced in last month 0.2 0.4 0.7 0.2 0.8
Hypertension (Self-reported) 3.4 9.4 10.1 -3.2 -3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 0.8 0.7 -0.9
Illnesses of father: Heart disease 0.3 0.4 0.7 0.4 0.8
Illnesses of siblings: Diabetes 0.7 0.9 1.6 1.3 -0.5
Smoking status: Previous 0.6 1.0 1.9 1.4 0.0
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.0 2.3 -1.3 -1.5
Whole body fat-free mass 3.4 19.6 30.7 -5.5 -2.9
Leg fat-free mass (right) 2.5 13.5 21.5 -4.6 -2.3
Arm fat percentage (left) 0.2 0.9 1.5 -0.6 1.2
Average weekly red wine intake 0.0 0.0 0.0 -0.1 0.2
Handedness (chirality/laterality): Left-handed 0.8 1.0 1.8 1.4 -0.5
Mood swings 0.9 1.6 3.1 1.8 0.3
Loneliness, isolation 2.6 3.5 6.0 2.4 1.0
Long-standing illness, disability or infirmity 0.3 0.5 0.8 -0.4 -0.9
Ever had bowel cancer screening 3.0 3.5 3.9 -2.0 -1.8
Diabetes diagnosed by doctor 0.3 0.5 1.0 0.0 -1.0
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.1 0.4 -0.0
Friendships satisfaction 0.2 0.2 0.4 0.6 -0.1
Qualifications: nursing, teaching 0.2 0.4 0.5 -0.5 0.7
Commuting to job workplace: Walk 0.1 0.1 0.1 -0.4 0.3
Eye problems/disorders: Cataract 0.5 0.6 1.0 1.0 0.5
Mouth/teeth dental problems: Mouth ulcers 1.3 2.0 2.4 -1.3 -1.6
Medication for cholesterol 3.7 5.7 7.2 2.7 2.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.1 -0.2 0.3
Back pain experienced in last month 0.3 0.5 0.8 -0.3 -0.9
Mineral and other dietary supplements 0.3 0.4 0.7 0.1 -0.8
Breast cancer (self-reported) 0.2 0.2 0.3 0.3 -0.5
Asthma (self-reported) 1.4 2.8 5.3 -0.5 -2.3
Osteoporosis (self-reported) 0.0 0.0 0.0 -0.0 -0.2
Osteoarthritis (self-reported) 5.1 6.6 9.7 1.9 3.1
Medication: Aspirin 0.7 0.9 1.6 0.3 -1.3
Medication: Gliclazide 0.3 0.3 0.5 0.7 -0.3
Illnesses of father: None of the above (group 1) 1.0 1.2 1.5 1.0 1.2
Smoking status: Current 1.5 2.5 3.8 1.9 1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.0 0.1 0.1 -0.3 -0.3
Whole body water mass 3.6 20.4 31.8 -5.6 -3.0
Leg predicted mass (right) 2.6 13.9 22.2 -4.7 -2.4
Arm fat mass (left) 0.7 3.0 5.9 -2.4 -0.3
Number of self-reported non-cancer illnesses 1.7 2.9 3.7 -1.5 -1.9
Average weekly champagne plus white wine intake 0.2 0.3 0.4 -0.7 -0.4
Miserableness 1.1 1.8 3.3 1.8 0.6
Guilty feelings 0.0 0.0 0.1 -0.1 -0.2
Wears glasses or contact lenses 1.1 1.3 1.6 1.3 1.0
Ever taken oral contraceptive pill 0.1 0.2 0.3 0.6 -0.1
Hearing aid user 0.0 0.0 0.1 0.2 0.3
Mother’s age at death 0.0 0.0 0.1 -0.1 -0.3
Financial situation satisfaction 0.0 0.0 0.0 0.1 -0.1
Tinnitus: Yes, now most or all of the time 0.7 0.8 1.1 1.0 0.8
Commuting to job workplace: Public transport 0.1 0.1 0.2 0.2 -0.4
Eye problems/disorders: Glaucoma 1.0 1.1 1.8 -1.3 -0.7
Medication: Blood pressure 4.4 8.4 12.0 -3.5 -2.2
Pain type(s) experienced in last month: Hip pain 0.3 0.4 0.8 -0.2 0.9
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.3 0.6 0.6
High cholesterol (Self-reported) 0.0 0.1 0.1 0.1 -0.3
Medication: Bendroflumethiazide 1.3 1.9 3.3 -0.7 -1.8
Medication: Paracetamol 1.7 2.6 3.4 1.9 1.3
Medication: Lisinopril 0.1 0.2 0.3 -0.3 -0.5
Medication: Atorvastatin 0.1 0.1 0.2 0.5 -0.1
Illnesses of father: High blood pressure 1.4 1.7 1.8 -1.3 -1.3
Alcohol drinker status: Never 0.3 0.3 0.6 -0.2 -0.8
Ever smoked 0.4 0.7 1.4 1.2 -0.1
Basal metabolic rate 3.4 18.8 30.4 -5.5 -2.7
Leg fat percentage (left) 0.3 1.1 2.0 -1.4 0.4
Arm fat-free mass (left) 3.8 19.4 30.2 -5.5 -2.9
Number of operations (self-reported) 0.6 0.9 1.3 -0.7 -1.1
Average weekly beer plus cider intake 0.2 0.3 0.5 -0.7 0.2
Irritability 1.2 2.0 3.4 1.9 0.7
Risk taking 1.1 1.6 3.2 1.8 0.2
Ever had prostate specific antigen (PSA) test 1.7 1.9 2.1 -1.5 -1.3
Fractured/broken bones in last 5 years 0.5 0.7 1.1 -1.1 -0.5
Age started oral contraceptive pill 1.2 1.5 2.1 -1.5 -0.9
Diastolic blood pressure, automated reading 1.7 5.4 5.7 -2.4 -2.3
Ever depressed for a whole week 3.4 4.1 7.1 2.7 1.1
Unable to work because of sickness or disability 0.2 0.3 0.4 0.5 0.6
Commuting to job workplace: Cycle 0.1 0.1 0.1 0.3 -0.4
Myopia 0.1 0.1 0.2 0.5 0.1
Vascular/heart problems diagnosed by doctor 2.9 8.0 8.9 3.0 2.7
Cholesterol lowering medication 0.5 0.8 0.9 -0.8 -0.9
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 1.7 -0.6 -1.3
Pain experienced in last month 0.1 0.1 0.2 0.1 0.5
Supplements: Calcium 0.2 0.2 0.3 -0.6 -0.1
Basal cell carcinoma (self-reported) 1.1 1.3 2.2 1.5 0.6
Heart attack/myocardial infarction (self-reported) 4.0 5.2 6.6 2.6 1.9
Deep venous thrombosis (DVT) (self-reported) 0.7 0.8 1.0 -1.0 -0.8
Heart disease (siblings) 0.1 0.2 0.3 0.6 -0.1
Alcohol drinker status: Previous 1.3 1.5 1.8 -1.0 -1.4
Pack years of smoking 1.6 2.4 2.5 1.5 1.6
Impedance of whole body 1.1 5.8 10.0 3.2 1.3
Leg fat mass (left) 0.7 2.6 5.1 -2.3 -0.0
Arm predicted mass (left) 4.2 21.2 31.5 -5.6 -3.3