[Hub]/) : Traits : Qualifications: None of the above :

chr1:43,073,464-45,157,738

Best TWAS P=1.98e-13 · Best GWAS P=2.21e-15 conditioned to 0.308

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous HYI 0.38 0.09 lasso 9 0.07 1.6e-06 4.8 6.4 1.5e-10 0.51 0.99 0.00 FALSE
2 GTEx Artery Aorta MED8 0.10 0.05 enet 13 0.08 4.6e-05 -3.8 -5.3 9.4e-08 -0.27 0.87 0.02 FALSE
3 GTEx Brain Cerebellar Hemisphere ARTN 0.45 0.36 enet 29 0.40 2.5e-11 5.7 6.5 6.1e-11 0.47 0.57 0.39 FALSE
4 GTEx Brain Cerebellum ARTN 0.47 0.33 lasso 5 0.43 6.0e-14 5.4 7.3 2.1e-13 0.70 0.24 0.75 FALSE
5 GTEx Brain Cortex ARTN 0.13 0.04 lasso 5 0.03 5.9e-02 7.2 6.5 5.7e-11 0.84 0.10 0.53 FALSE
6 GTEx Breast Mammary Tissue (Female) TIE1 0.10 0.07 enet 10 0.07 3.5e-03 -5.2 5.2 2.0e-07 0.24 0.17 0.05 FALSE
7 GTEx Breast Mammary Tissue (Female) ST3GAL3 0.03 -0.01 lasso 2 0.01 1.6e-01 6.3 6.3 2.7e-10 0.42 0.05 0.08 TRUE
8 GTEx Cells Transformed fibroblasts CCDC24 0.07 0.00 enet 16 0.02 9.5e-03 6.4 5.4 8.5e-08 0.67 0.07 0.70 FALSE
9 GTEx Heart Left Ventricle MED8 0.08 0.01 lasso 3 0.01 1.2e-01 -6.7 5.9 3.9e-09 0.34 0.19 0.06 FALSE
10 GTEx Muscle Skeletal B4GALT2 0.04 0.05 lasso 2 0.03 6.4e-04 6.1 -5.9 4.2e-09 -0.50 0.16 0.44 FALSE
11 GTEx Muscle Skeletal ST3GAL3 0.10 0.01 enet 27 0.01 1.6e-02 -6.7 6.1 9.3e-10 0.36 0.39 0.28 FALSE
12 GTEx Muscle Skeletal RP11-7O11.3 0.05 0.02 lasso 3 0.02 7.2e-03 7.7 -7.3 2.0e-13 -0.64 0.04 0.74 TRUE
13 GTEx Nerve Tibial MED8 0.13 0.07 enet 11 0.16 3.6e-11 -3.8 -6.5 6.3e-11 -0.62 0.92 0.08 TRUE
14 GTEx Pancreas HYI 0.22 0.16 enet 9 0.20 9.7e-09 4.7 5.4 7.6e-08 0.42 0.97 0.00 FALSE
15 GTEx Stomach HYI 0.16 0.06 lasso 6 0.07 4.1e-04 4.6 6.2 6.3e-10 0.54 0.35 0.20 FALSE
16 GTEx Thyroid ARTN 0.07 0.04 lasso 3 0.03 1.2e-03 7.7 6.4 1.5e-10 0.68 0.06 0.84 FALSE
17 METSIM Adipose ARTN 0.05 0.04 bslmm 412 0.03 1.3e-05 5.8 7.3 3.4e-13 0.71 0.36 0.64 FALSE
18 ROSMAP Brain Pre-frontal Cortex ARTN 0.14 0.19 lasso 4 0.18 3.0e-23 5.8 5.8 8.6e-09 0.38 1.00 0.00 FALSE
19 ROSMAP Brain Pre-frontal Cortex HYI 0.35 0.35 lasso 7 0.36 8.6e-48 4.7 5.2 2.0e-07 0.38 1.00 0.00 FALSE
20 YFS Blood CCDC24 0.36 0.43 lasso 7 0.44 6.5e-160 6.2 6.1 1.3e-09 0.43 1.00 0.00 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA0467 0.07 0.03 enet 5 0.04 7.5e-05 4.8 5.5 3.0e-08 0.56 0.02 0.98 FALSE
22 The Cancer Genome Atlas Lung Adenocarcinoma KDM4A 0.03 0.02 enet 5 0.02 1.5e-03 -1.7 -5.5 4.2e-08 -0.68 0.03 0.55 FALSE
23 The Cancer Genome Atlas Pancreatic Adenocarcinoma HYI 0.26 0.15 lasso 3 0.13 3.7e-06 4.6 5.2 2.6e-07 0.32 0.02 0.94 FALSE
24 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ARTN 0.08 0.10 lasso 1 0.08 3.7e-04 6.1 6.1 9.8e-10 0.45 0.02 0.78 FALSE
25 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PTPRF 0.07 0.01 blup 85 0.04 1.3e-02 6.0 -6.4 1.5e-10 -0.89 0.01 0.87 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma DPH2 0.03 0.03 enet 7 0.04 5.8e-05 5.7 6.8 1.4e-11 0.52 0.05 0.91 FALSE
27 The Cancer Genome Atlas Rectum Adenocarcinoma HYI 0.23 0.08 blup 34 0.14 3.1e-04 4.7 5.6 2.4e-08 0.46 0.01 0.84 FALSE