[Hub]/) : Traits : Qualifications: None of the above : ← →

chr12:122,258,047-124,591,385

Best TWAS P=1.45e-13 · Best GWAS P=6.16e-12 conditioned to 0.662

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
97	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CDK2AP1	0.12	0.14	blup	34	0.15	7.2e-07	-6.7	7.4	1.4e-13	-0.88	0.01	0.98	TRUE
44	GTEx	Muscle Skeletal	RSRC2	0.06	0.03	enet	7	0.04	9.6e-05	4.6	5.3	1.1e-07	-0.03	0.43	0.10	TRUE
22	GTEx	Cells Transformed fibroblasts	C12orf65	0.07	0.05	lasso	4	0.04	5.8e-04	-6.6	7.4	1.8e-13	-0.86	0.03	0.95	FALSE
7	GTEx	Adipose Visceral Omentum	RP11-282O18.3	0.14	0.11	enet	12	0.10	6.7e-06	-6.4	7.2	9.0e-13	-0.93	0.03	0.97	FALSE
5	GTEx	Adipose Visceral Omentum	MPHOSPH9	0.07	0.02	lasso	4	0.00	3.5e-01	-6.4	-7.0	1.9e-12	0.87	0.04	0.73	FALSE
53	GTEx	Pancreas	ARL6IP4	0.07	0.07	lasso	2	0.07	9.6e-04	-6.7	6.9	4.8e-12	-0.85	0.05	0.84	FALSE
96	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CDK2AP1	0.07	0.06	enet	7	0.06	7.0e-05	-6.5	6.9	5.9e-12	-0.90	0.02	0.91	FALSE
4	GTEx	Adipose Subcutaneous	RP11-282O18.3	0.15	0.14	lasso	7	0.15	2.0e-12	-6.9	6.8	8.3e-12	-0.97	0.02	0.98	FALSE
81	The Cancer Genome Atlas	Colon Adenocarcinoma	RILPL2	0.09	0.09	blup	43	0.08	3.1e-05	-6.5	-6.8	9.3e-12	0.87	0.01	0.99	FALSE
101	The Cancer Genome Atlas	Stomach Adenocarcinoma	CDK2AP1	0.09	0.10	lasso	2	0.10	1.8e-07	-6.5	6.8	1.1e-11	-0.91	0.02	0.98	FALSE
19	GTEx	Breast Mammary Tissue (Female)	RP11-282O18.3	0.09	0.07	enet	8	0.08	2.8e-03	-6.4	6.8	1.3e-11	-0.88	0.07	0.79	FALSE
65	GTEx	Testis	CDK2AP1	0.20	0.14	lasso	5	0.13	2.0e-06	-6.8	6.8	1.5e-11	-0.75	0.02	0.98	FALSE
17	GTEx	Breast Mammary Tissue	RP11-282O18.3	0.10	0.06	lasso	6	0.08	5.4e-05	-6.7	6.7	1.6e-11	-0.94	0.06	0.92	FALSE
45	GTEx	Muscle Skeletal	SETD8	0.16	0.02	lasso	4	0.03	3.8e-04	-6.5	-6.7	1.7e-11	0.89	0.03	0.96	FALSE
16	GTEx	Breast Mammary Tissue	CDK2AP1	0.08	0.06	lasso	3	0.07	1.2e-04	-6.7	6.7	2.0e-11	-0.95	0.05	0.93	FALSE
49	GTEx	Nerve Tibial	ABCB9	0.06	0.04	lasso	3	0.05	3.5e-04	-6.8	-6.7	2.0e-11	0.96	0.03	0.97	FALSE
102	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CDK2AP1	0.13	0.10	blup	34	0.11	8.2e-05	-6.8	6.7	2.0e-11	-0.86	0.01	0.97	FALSE
59	GTEx	Skin Sun Exposed Lower leg	CDK2AP1	0.21	0.22	lasso	5	0.22	3.4e-18	-6.5	6.7	2.3e-11	-0.93	0.05	0.95	FALSE
3	GTEx	Adipose Subcutaneous	CDK2AP1	0.20	0.18	lasso	11	0.19	1.0e-15	-6.5	6.7	2.4e-11	-0.95	0.02	0.98	FALSE
43	GTEx	Lung	RP11-282O18.3	0.06	0.02	lasso	7	0.00	6.1e-01	-6.5	6.7	2.4e-11	-0.93	0.03	0.94	FALSE
6	GTEx	Adipose Visceral Omentum	CDK2AP1	0.14	0.14	lasso	4	0.11	2.7e-06	-6.4	6.7	2.8e-11	-0.89	0.03	0.97	FALSE
41	GTEx	Lung	CDK2AP1	0.08	0.03	lasso	4	0.00	2.0e-01	-6.5	6.6	3.2e-11	-0.90	0.04	0.94	FALSE
40	GTEx	Heart Left Ventricle	ABCB9	0.10	0.14	lasso	5	0.10	4.2e-06	-6.7	-6.6	3.5e-11	0.76	0.04	0.96	FALSE
18	GTEx	Breast Mammary Tissue (Female)	CDK2AP1	0.08	0.03	lasso	3	0.02	6.4e-02	-6.1	6.6	3.8e-11	-0.86	0.05	0.60	FALSE
64	GTEx	Testis	MPHOSPH9	0.28	0.27	enet	23	0.32	1.3e-14	-6.1	-6.6	3.8e-11	0.87	0.09	0.91	FALSE
77	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDK2AP1	0.07	0.08	lasso	7	0.08	5.0e-16	-6.6	6.6	4.2e-11	-0.91	0.02	0.98	FALSE
80	The Cancer Genome Atlas	Colon Adenocarcinoma	CDK2AP1	0.12	0.17	lasso	4	0.17	6.3e-10	-6.6	6.6	4.3e-11	-0.92	0.02	0.98	FALSE
90	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CDK2AP1	0.11	0.11	enet	5	0.11	1.2e-05	-6.5	6.6	4.3e-11	-0.92	0.02	0.97	FALSE
84	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CDK2AP1	0.14	0.15	lasso	2	0.14	7.8e-16	-6.6	6.6	4.5e-11	-0.91	0.01	0.99	FALSE
88	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PITPNM2	0.06	0.07	lasso	5	0.09	1.2e-05	-6.4	6.6	4.5e-11	-0.83	0.04	0.96	FALSE
87	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CDK2AP1	0.12	0.10	lasso	2	0.11	6.3e-07	-6.6	6.6	4.6e-11	-0.91	0.02	0.98	FALSE
104	The Cancer Genome Atlas	Thyroid Carcinoma	MPHOSPH9	0.27	0.09	lasso	4	0.09	9.8e-09	-6.6	-6.6	4.7e-11	0.71	0.02	0.98	FALSE
75	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CDK2AP1	0.09	0.08	lasso	2	0.06	5.9e-06	-6.6	6.6	5.1e-11	-0.92	0.02	0.98	FALSE
79	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CDK2AP1	0.07	0.07	blup	34	0.05	1.1e-03	-6.4	6.6	5.1e-11	-0.89	0.02	0.86	FALSE
91	The Cancer Genome Atlas	Lung Adenocarcinoma	CDK2AP1	0.03	0.04	lasso	1	0.04	1.2e-05	-6.6	6.6	5.1e-11	-0.92	0.02	0.98	FALSE
103	The Cancer Genome Atlas	Thyroid Carcinoma	CDK2AP1	0.08	0.10	lasso	2	0.10	1.3e-09	-6.5	6.6	5.3e-11	-0.92	0.02	0.98	FALSE
58	GTEx	Skin Not Sun Exposed Suprapubic	RP11-282O18.3	0.13	0.10	lasso	6	0.09	1.9e-05	-6.1	6.5	5.9e-11	-0.89	0.14	0.86	FALSE
69	GTEx	Thyroid	CDK2AP1	0.08	0.09	enet	7	0.10	8.2e-08	-6.5	6.5	5.9e-11	-0.91	0.08	0.92	FALSE
56	GTEx	Skin Not Sun Exposed Suprapubic	CDK2AP1	0.17	0.12	lasso	10	0.12	3.4e-07	-6.1	6.5	6.0e-11	-0.90	0.13	0.87	FALSE
8	GTEx	Artery Aorta	CDK2AP1	0.17	0.19	lasso	2	0.15	8.0e-09	-6.5	6.5	6.1e-11	-0.92	0.07	0.93	FALSE
63	GTEx	Stomach	MPHOSPH9	0.17	0.08	lasso	5	0.10	1.2e-05	-6.6	-6.5	6.4e-11	0.92	0.06	0.92	FALSE
29	GTEx	Colon Transverse	RP11-282O18.3	0.18	0.19	enet	8	0.19	1.8e-09	-6.1	6.5	7.7e-11	-0.93	0.05	0.95	FALSE
55	GTEx	Pancreas	RP11-282O18.3	0.22	0.24	lasso	5	0.24	2.3e-10	-6.5	6.5	7.7e-11	-0.92	0.06	0.94	FALSE
27	GTEx	Colon Transverse	CDK2AP1	0.17	0.19	enet	7	0.22	1.4e-10	-6.1	6.5	8.3e-11	-0.94	0.06	0.94	FALSE
11	GTEx	Artery Tibial	MPHOSPH9	0.05	0.03	lasso	3	0.03	2.2e-03	-6.1	-6.5	9.3e-11	0.84	0.11	0.82	FALSE
10	GTEx	Artery Aorta	RP11-282O18.3	0.18	0.19	lasso	9	0.16	4.3e-09	-6.5	6.5	9.8e-11	-0.91	0.07	0.93	FALSE
85	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDK2AP1	0.11	0.13	lasso	5	0.14	5.9e-16	-6.5	6.5	1.0e-10	-0.91	0.02	0.98	FALSE
15	GTEx	Artery Tibial	RP11-282O18.3	0.17	0.08	enet	26	0.10	2.4e-08	-6.1	6.4	1.2e-10	-0.64	0.08	0.92	FALSE
54	GTEx	Pancreas	SETD8	0.20	0.12	lasso	5	0.13	3.4e-06	-6.5	6.4	1.3e-10	-0.93	0.03	0.97	FALSE
47	GTEx	Nerve Tibial	CDK2AP1	0.11	0.11	enet	25	0.09	4.4e-07	-6.9	6.4	1.4e-10	-0.93	0.02	0.98	FALSE
94	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CDK2AP1	0.04	0.04	lasso	3	0.03	3.8e-04	-6.5	6.4	1.4e-10	-0.92	0.02	0.94	FALSE
25	GTEx	Cells Transformed fibroblasts	RP11-282O18.3	0.25	0.29	enet	16	0.28	2.2e-21	-6.5	6.4	1.6e-10	-0.92	0.05	0.95	FALSE
31	GTEx	Esophagus Mucosa	CDK2AP1	0.30	0.36	lasso	5	0.38	1.9e-26	-6.2	6.4	1.7e-10	-0.90	0.12	0.88	FALSE
48	GTEx	Nerve Tibial	C12orf65	0.05	0.07	lasso	3	0.06	3.0e-05	-6.1	6.4	1.8e-10	-0.79	0.10	0.83	FALSE
33	GTEx	Esophagus Mucosa	RP11-282O18.3	0.29	0.34	lasso	4	0.34	1.9e-23	-6.6	6.4	1.9e-10	-0.91	0.07	0.93	FALSE
52	GTEx	Pancreas	CDK2AP1	0.24	0.27	lasso	3	0.26	3.1e-11	-6.1	6.4	1.9e-10	-0.90	0.08	0.92	FALSE
21	GTEx	Cells Transformed fibroblasts	CDK2AP1	0.31	0.32	lasso	8	0.35	8.5e-27	-6.5	6.4	2.1e-10	-0.92	0.05	0.95	FALSE
28	GTEx	Colon Transverse	ABCB9	0.08	0.07	enet	5	0.09	5.3e-05	-6.8	-6.3	2.2e-10	0.92	0.02	0.97	FALSE
100	The Cancer Genome Atlas	Prostate Adenocarcinoma	CDK2AP1	0.06	0.07	lasso	2	0.06	1.7e-06	-6.5	6.3	2.3e-10	-0.92	0.02	0.98	FALSE
70	GTEx	Thyroid	RP11-282O18.3	0.06	0.06	enet	6	0.06	3.6e-05	-6.5	6.3	2.4e-10	-0.91	0.08	0.92	FALSE
61	GTEx	Skin Sun Exposed Lower leg	RP11-282O18.3	0.17	0.20	lasso	6	0.20	2.2e-16	-6.5	6.3	3.0e-10	-0.92	0.04	0.96	FALSE
9	GTEx	Artery Aorta	C12orf65	0.11	0.07	lasso	10	0.08	5.8e-05	-6.1	6.3	3.1e-10	-0.77	0.07	0.91	FALSE
36	GTEx	Esophagus Muscularis	C12orf65	0.06	0.04	lasso	4	0.04	2.0e-03	-6.5	6.3	3.2e-10	-0.87	0.06	0.91	FALSE
105	The Cancer Genome Atlas	Thyroid Carcinoma	OGFOD2	0.02	0.00	enet	4	0.02	2.7e-03	-5.5	-6.3	3.2e-10	0.60	0.01	0.53	FALSE
71	METSIM	Adipose	CDK2AP1	0.11	0.14	enet	23	0.14	1.7e-20	-6.4	6.2	4.2e-10	-0.86	0.08	0.92	FALSE
13	GTEx	Artery Tibial	ABCB9	0.04	0.02	lasso	2	0.01	3.0e-02	-5.3	-6.2	5.8e-10	0.81	0.10	0.83	FALSE
68	GTEx	Thyroid	PITPNM2	0.04	0.07	lasso	2	0.06	1.6e-05	-6.2	-6.2	5.8e-10	0.87	0.16	0.82	FALSE
20	GTEx	Cells Transformed fibroblasts	OGFOD2	0.10	0.07	lasso	7	0.07	3.1e-06	-5.4	-6.2	5.9e-10	0.81	0.21	0.79	FALSE
12	GTEx	Artery Tibial	CDK2AP1	0.17	0.07	enet	36	0.09	1.1e-07	-6.1	6.1	9.3e-10	-0.64	0.08	0.92	FALSE
42	GTEx	Lung	ABCB9	0.04	0.02	lasso	3	0.02	8.0e-03	-6.2	-6.1	9.7e-10	0.84	0.10	0.74	FALSE
14	GTEx	Artery Tibial	SETD8	0.07	0.03	lasso	7	0.03	2.2e-03	-6.9	-6.1	1.1e-09	0.94	0.02	0.96	FALSE
26	GTEx	Colon Sigmoid	ABCB9	0.18	0.16	lasso	6	0.15	4.8e-06	-6.1	-6.1	1.1e-09	0.88	0.04	0.95	FALSE
39	GTEx	Heart Left Ventricle	MPHOSPH9	0.06	0.04	lasso	5	0.04	4.2e-03	-6.2	-6.1	1.1e-09	0.80	0.06	0.82	FALSE
67	GTEx	Thyroid	MPHOSPH9	0.10	0.08	enet	20	0.09	2.0e-07	-6.3	-6.0	1.5e-09	0.84	0.12	0.88	FALSE
78	The Cancer Genome Atlas	Breast Invasive Carcinoma	RILPL2	0.02	0.01	enet	8	0.01	2.6e-02	-6.5	-6.0	1.6e-09	0.88	0.01	0.96	FALSE
34	GTEx	Esophagus Muscularis	MPHOSPH9	0.18	0.18	enet	17	0.18	4.8e-11	-5.9	-6.0	1.7e-09	0.82	0.26	0.74	FALSE
46	GTEx	Nerve Tibial	MPHOSPH9	0.07	0.04	lasso	4	0.01	7.0e-02	-6.1	-6.0	1.7e-09	0.86	0.12	0.71	FALSE
23	GTEx	Cells Transformed fibroblasts	ABCB9	0.08	0.12	enet	7	0.12	4.3e-09	-5.1	-6.0	2.0e-09	0.76	0.59	0.41	FALSE
38	GTEx	Esophagus Muscularis	RP11-282O18.3	0.19	0.11	lasso	6	0.10	2.1e-06	-6.2	6.0	2.1e-09	-0.88	0.05	0.95	FALSE
50	GTEx	Nerve Tibial	RP11-282O18.3	0.10	0.10	enet	28	0.08	1.9e-06	-6.9	6.0	2.4e-09	-0.89	0.01	0.99	FALSE
72	YFS	Blood	MPHOSPH9	0.05	0.07	enet	31	0.07	3.7e-23	-6.3	-5.9	3.2e-09	0.85	0.16	0.84	FALSE
92	The Cancer Genome Atlas	Lung Adenocarcinoma	RILPL2	0.04	0.02	blup	43	0.02	6.1e-04	-5.4	-5.9	3.3e-09	0.72	0.02	0.92	FALSE
35	GTEx	Esophagus Muscularis	CDK2AP1	0.17	0.10	enet	18	0.11	4.6e-07	-6.2	5.9	3.7e-09	-0.82	0.06	0.94	FALSE
93	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ABCB9	0.06	0.06	enet	7	0.07	5.2e-08	-5.5	-5.9	3.8e-09	0.73	0.05	0.95	FALSE
57	GTEx	Skin Not Sun Exposed Suprapubic	ABCB9	0.13	0.15	lasso	11	0.11	2.1e-06	-5.1	-5.9	4.0e-09	0.76	0.07	0.93	FALSE
106	The Cancer Genome Atlas	Thyroid Carcinoma	SBNO1	0.03	0.01	blup	59	0.02	9.4e-03	-6.4	5.9	4.3e-09	-0.71	0.01	0.54	FALSE
37	GTEx	Esophagus Muscularis	ABCB9	0.10	0.08	lasso	6	0.05	3.8e-04	-6.6	-5.8	5.1e-09	0.89	0.08	0.90	FALSE
86	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C12orf65	0.05	0.04	blup	34	0.05	1.0e-03	-4.5	5.8	5.7e-09	-0.73	0.01	0.88	FALSE
32	GTEx	Esophagus Mucosa	ABCB9	0.10	0.03	lasso	5	0.05	5.4e-04	-6.4	-5.8	7.3e-09	0.86	0.07	0.92	FALSE
98	The Cancer Genome Atlas	Prostate Adenocarcinoma	ABCB9	0.04	0.05	enet	10	0.05	1.2e-05	-5.5	-5.7	1.0e-08	0.63	0.08	0.92	FALSE
2	GTEx	Adipose Subcutaneous	ZCCHC8	0.04	0.00	lasso	7	0.00	1.4e-01	-1.9	-5.7	1.2e-08	0.45	0.03	0.83	FALSE
95	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	OGFOD2	0.02	0.04	lasso	3	0.03	1.3e-04	-5.5	-5.5	3.0e-08	0.67	0.02	0.92	FALSE
99	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARL6IP4	0.03	0.04	blup	17	0.04	1.6e-05	-5.5	5.5	3.4e-08	-0.70	0.04	0.94	FALSE
51	GTEx	Pancreas	MPHOSPH9	0.14	0.01	enet	31	0.07	9.3e-04	-6.4	5.5	4.1e-08	-0.55	0.06	0.68	FALSE
30	GTEx	Esophagus Gastroesophageal Junction	RP11-282O18.3	0.16	0.06	lasso	9	0.07	2.3e-03	-6.6	5.5	5.0e-08	-0.82	0.06	0.64	FALSE
24	GTEx	Cells Transformed fibroblasts	SETD8	0.10	0.12	enet	9	0.09	1.4e-07	-4.5	-5.5	5.2e-08	0.82	0.08	0.92	FALSE
74	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ABCB9	0.05	0.04	enet	5	0.04	2.4e-04	-6.2	-5.4	5.6e-08	0.76	0.00	0.97	FALSE
73	YFS	Blood	SBNO1	0.03	0.03	lasso	6	0.03	1.2e-09	-6.6	5.4	5.9e-08	-0.88	0.09	0.91	FALSE
66	GTEx	Testis	ABCB9	0.14	0.05	lasso	3	0.06	8.0e-04	-2.5	5.4	6.5e-08	-0.46	0.07	0.74	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SETD8	0.04	0.01	blup	352	0.02	2.8e-03	-4.5	5.4	7.8e-08	-0.73	0.09	0.89	FALSE
83	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ARL6IP4	0.03	0.03	lasso	2	0.02	1.9e-03	-5.5	5.3	9.4e-08	-0.65	0.05	0.41	FALSE
82	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ABCB9	0.03	0.02	enet	9	0.03	3.4e-04	-6.2	-5.2	1.5e-07	0.75	0.00	0.90	FALSE
60	GTEx	Skin Sun Exposed Lower leg	ABCB9	0.09	0.08	lasso	5	0.08	4.3e-07	-5.1	-5.2	1.6e-07	0.70	0.09	0.90	FALSE
89	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABCB9	0.19	0.22	enet	9	0.22	7.7e-11	-5.3	-5.2	2.2e-07	0.67	0.17	0.83	FALSE
76	The Cancer Genome Atlas	Breast Invasive Carcinoma	C12orf65	0.02	0.00	enet	6	0.01	2.4e-03	-6.7	5.2	2.6e-07	-0.43	0.01	0.75	FALSE
62	GTEx	Small Intestine Terminal Ileum	ABCB9	0.23	0.21	enet	12	0.22	1.0e-05	-6.2	-5.1	2.7e-07	0.82	0.08	0.74	FALSE