TWAS hub - RSRC2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Muscle Skeletal	0.0585	0.0272	0.00088	0.032	NA	0.039	NA	0.036	0.00037	NA	9.6e-05	NA	0.00017
2	YFS	Blood	0.0294	0.0164	0.00280	0.001	0.005	0.002	0.006	0.000	0.18000	0.0089	4.8e-02	0.0042	0.42000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hip circumference	7.6	32.7	65.3	-8.1	-0.1
Weight	7.5	37.1	74.2	-8.6	-0.2
Qualifications: None of the above	6.7	14.3	28.2	5.3	0.7
Bipolar Disorder (2011)	6.6	6.4	12.7	-3.6	0.2
Leg fat-free mass (left)	6.6	35.1	69.9	-8.4	0.4
Leg predicted mass (left)	6.6	35.0	69.8	-8.4	0.5
Trunk fat mass	6.6	28.3	55.5	-7.5	-1.0
Whole body fat mass	6.2	25.9	50.8	-7.1	-1.0
Leg fat-free mass (right)	6.2	33.2	66.4	-8.2	0.2
Leg predicted mass (right)	6.2	33.3	66.6	-8.2	0.2
Basal metabolic rate	6.0	33.4	66.6	-8.2	0.5
Arm fat mass (right)	5.6	23.2	46.1	-6.8	-0.6
Supplements: Glucosamine	5.5	7.2	12.1	-3.5	-1.5
Leg fat mass (right)	5.4	21.0	41.6	-6.5	-0.5
Leg fat mass (left)	5.4	20.9	41.1	-6.4	-0.9
BMI	5.3	30.5	60.7	-7.8	-0.5
Whole body fat-free mass	5.3	30.5	60.5	-7.8	0.7
Whole body water mass	5.2	29.4	58.4	-7.6	0.6
Medication: Allopurinol	5.1	6.8	12.6	3.6	1.0
Arm fat mass (left)	4.8	19.9	39.1	-6.3	-0.8
Trunk fat-free mass	4.6	26.2	51.4	-7.2	1.0
Arm predicted mass (left)	4.6	23.3	46.3	-6.8	0.6
Trunk fat percentage	4.5	18.1	34.7	-5.9	-1.2
Trunk predicted mass	4.5	26.0	51.1	-7.1	0.9
Gout (self-reported)	4.5	6.2	10.2	3.2	1.5
Arm fat-free mass (left)	4.5	23.0	45.8	-6.8	0.4
Arm fat-free mass (right)	4.4	22.5	44.7	-6.7	0.4
Arm predicted mass (right)	4.4	22.7	45.3	-6.7	0.3
High cholesterol (Self-reported)	4.4	7.8	11.2	2.1	-3.3
Body fat percentage	4.3	16.9	32.1	-5.7	-1.3
Alzheimer’s Disease (in father)	4.0	4.4	5.7	-2.4	1.8
Vascular/heart problems diagnosed by doctor	4.0	10.9	21.7	-4.7	0.3
Illnesses of siblings: Diabetes	3.8	4.7	7.6	2.8	1.3
Arm fat percentage (right)	3.7	14.5	27.3	-5.2	-1.3
Waist Hip Ratio (WHR)	3.6	16.2	26.3	5.1	-2.5
High blood pressure	3.6	10.2	20.3	4.5	0.1
Frequency of tiredness / lethargy in last 2 weeks	3.6	5.9	11.0	-3.3	-0.9
Standing height	3.6	35.6	70.1	-8.4	1.1
Chronotype (morning person)	3.5	8.1	14.8	3.8	1.2
Arm fat percentage (left)	3.5	14.0	26.0	-5.1	-1.4
Medication: Atenolol	3.4	4.3	5.9	2.4	-1.6
Pain all over the body in last month	3.3	3.6	4.2	-2.0	-1.7
Neuroticism (2016)	3.2	4.6	9.0	3.0	0.5
Medication: Blood pressure	3.2	6.1	12.0	3.5	-0.3
Bipolar Disorder or Schizophrenia	3.1	7.6	14.5	-3.8	-0.9
Leg fat percentage (right)	3.1	11.1	21.5	-4.6	-0.8
Height	3.0	58.0	115.7	-10.8	0.6
Body mass index (BMI)	3.0	12.7	24.9	-5.0	-0.7
Medication: Simvastatin	3.0	4.3	4.5	2.1	-2.1
Forced vital capacity (FVC), Best measure	3.0	11.0	22.0	-4.7	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	3.0	3.8	7.7	-2.8	0.0
Qualifications: College or University degree	3.0	9.4	18.8	-4.3	0.1
Leg fat percentage (left)	3.0	10.9	20.5	-4.5	-1.2
Age started oral contraceptive pill	3.0	3.8	5.7	2.4	1.3
Cholesterol lowering medication	3.0	4.4	5.3	2.3	-1.9
Severe depression (siblings)	2.9	3.3	6.3	-2.5	0.5
Sitting height	2.9	20.9	38.1	-6.2	1.9
Waist circumference	2.9	10.5	19.1	-4.4	-1.3
Forced vital capacity (FVC)	2.9	11.2	21.8	-4.7	0.8
Hypertension (Self-reported)	2.9	8.0	15.7	4.0	-0.5
Schizophrenia (2014)	2.8	6.1	9.0	-3.0	-1.8
Qualifications: nursing, teaching	2.8	4.4	8.6	-2.9	-0.3
Mouth/teeth dental problems: Mouth ulcers	2.8	4.4	8.0	2.8	-0.9
Pain type(s) experienced in last month: Hip pain	2.8	3.6	6.3	-2.5	-0.9
Systolic Blood Pressure	2.7	13.6	27.1	5.2	-0.2
Comparative height size at age 10	2.6	14.2	28.2	-5.3	0.5
Age at last live birth	2.6	3.8	4.8	-2.2	-1.7
Supplements: Zinc	2.5	2.8	4.5	-2.1	-1.0
Medication: Atorvastatin	2.5	3.1	6.2	0.1	-2.5
Commuting to job workplace: Cycle	2.5	3.0	4.7	1.2	-2.2
Supplements: Calcium	2.5	2.7	5.3	0.4	-2.3
Bipolar Disorder (2018)	2.4	3.8	7.5	-2.7	0.3
Schizophrenia (2018)	2.4	4.9	7.2	-2.7	-1.6
Age at First Birth	2.4	3.5	6.7	-0.5	-2.6
Mouth/teeth dental problems	2.3	3.5	6.6	-2.6	0.6
Medication for cholesterol	2.3	3.5	6.4	-2.5	0.8
Mineral and other dietary supplements	2.3	3.1	4.4	2.1	1.3
Cardiovascular Disease	2.2	7.2	11.1	3.3	-1.8
Hayfever, allergic rhinitis or eczema	2.2	4.9	8.3	-2.9	-1.2
Hair/balding pattern: Pattern 3	2.2	3.3	6.4	0.3	2.5
Noisy workplace	2.2	2.7	5.3	2.3	0.3
Depression (self-reported)	2.2	2.6	3.6	-1.9	1.2
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	2.7	1.6	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.5	4.3	-2.1	-0.9
Ever had hysterectomy (womb removed)	2.1	2.4	4.8	2.2	-0.1
Breast cancer (self-reported)	2.1	2.5	3.9	1.0	2.0
Allergy or Eczema	2.0	5.4	8.7	-3.0	-1.4
Time employed in main current job	2.0	2.3	4.1	-2.0	-0.8
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	4.5	-0.1	2.1
Back pain experienced in last month	2.0	3.0	4.6	-2.1	1.1
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	4.1	2.0	-0.4
Relative age voice broke	1.9	2.8	5.5	0.4	2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	2.9	1.3	1.7
Average weekly champagne plus white wine intake	1.9	2.6	4.5	-0.9	2.1
Supplements: Fish oil (including cod liver oil)	1.9	2.5	4.4	-2.1	-0.8
Medication: Metformin	1.8	2.5	4.6	2.1	-0.6
Stomach or abdominal pain in last month	1.8	2.2	2.7	1.3	1.7
Forced expiratory volume in 1-second (FEV1)	1.8	6.0	11.0	-3.3	1.0
Mouth/teeth dental problems: Dentures	1.8	3.1	6.1	2.5	-0.2
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	3.2	-1.8	-1.2
Medication: Cholesterol lowering	1.8	2.8	5.6	0.0	-2.4
Mouth/teeth dental problems: Loose teeth	1.8	2.1	3.9	2.0	-0.5
Medication: Aspirin	1.8	2.4	3.1	1.3	-1.8
Allergy	1.7	4.0	7.2	2.7	0.9
Birth weight	1.7	3.8	4.8	-2.2	-1.6
Age at first live birth	1.7	3.0	3.1	-1.8	-1.7
Guilty feelings	1.7	2.5	5.1	0.2	-2.2
Heart disease (siblings)	1.7	2.1	4.1	-0.2	-2.0
Body Mass Index (BMI) (2010)	1.6	2.2	4.1	-2.0	-0.5
Type 2 Diabetes (T2D) (2018)	1.6	3.0	3.3	1.8	-1.6
Number of treatments/medications taken	1.6	2.9	5.7	0.1	-2.4
Medication: Co-codamol	1.6	1.8	3.6	-1.9	0.2
Maternal smoking around birth	1.6	2.3	4.4	-2.1	-0.5
Migraine (self-reported)	1.6	2.0	3.0	1.7	1.1
Osteoarthritis (self-reported)	1.6	2.0	3.2	-1.8	-0.9
Father’s age at death	1.5	2.0	3.9	0.4	2.0
Shortness of breath walking on level ground	1.5	1.8	3.6	-1.9	-0.0
Medication: Aspirin	1.5	1.9	2.9	1.0	-1.7
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	3.4	-1.8	-0.4
Qualifications: CSEs or equivalent	1.4	1.9	3.7	1.9	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.6	9.0	-3.0	0.4
Worry too long after embarrassment	1.4	2.3	4.5	2.1	0.5
Eye problems/disorders: Cataract	1.4	1.6	2.8	-0.7	1.7
Alcohol drinker status: Never	1.4	1.7	2.2	1.5	1.1
Ever had prostate specific antigen (PSA) test	1.4	1.7	2.1	-1.4	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	2.3	-1.5	-1.1
Ever unenthusiastic/disinterested for a whole week	1.3	1.5	2.5	-1.6	0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	5.1	-2.3	0.6
Triglycerides	1.2	1.9	3.6	1.9	-0.6
Impedance of leg (right)	1.2	5.7	11.5	3.4	-0.0
Impedance of leg (left)	1.2	6.0	11.6	3.4	-0.6
Prospective memory result	1.2	1.5	2.0	1.4	0.9
Medication: Ibuprofen	1.2	1.4	2.0	-1.4	-0.9
Pulse rate, automated reading	1.2	3.9	7.8	-2.8	-0.1
Loneliness, isolation	1.2	1.6	3.1	-0.3	-1.8
Friendships satisfaction	1.2	1.5	3.0	0.1	-1.7
Alzheimer’s Disease (including proxy)	1.1	1.6	1.9	-1.4	1.1
LDL Cholesterol	1.1	1.7	3.3	1.8	0.2
Hypothyroidism (self reported)	1.1	2.4	3.6	-1.9	-1.1
Systolic blood pressure, automated reading	1.1	3.3	6.5	2.5	-0.2
Diabetes (mother)	1.1	1.4	2.5	1.6	0.5
Townsend deprivation index at recruitment	1.1	1.5	2.3	1.5	-0.8
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	2.3	-0.9	-1.5
Exposure to tobacco smoke at home	1.1	1.3	1.8	-1.3	-0.9
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	3.5	-0.3	1.9
Had major operations	1.1	1.2	1.6	-1.3	1.0
Commuting to job workplace: Public transport	1.1	1.4	2.7	0.2	-1.6
Mean Putamen Volume	1.0	1.2	1.5	-1.2	-0.9
HDL Cholesterol	1.0	1.7	3.2	-1.8	0.5
Blood Eosinophil Count	1.0	7.7	8.7	-2.6	-3.0
Blood Platelet Count	1.0	11.9	18.0	2.4	-4.2
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.7	-1.6	-0.5
Serious illness, injury or assault to yourself	1.0	1.2	2.0	-1.4	0.7
Medication: Ramipril	1.0	1.3	1.4	1.1	-1.2
Medication: Paracetamol	1.0	1.7	3.3	1.8	-0.2
Medication for pain relief, constipation, heartburn	1.0	1.7	3.3	-0.3	1.8
Heart disease (mother)	1.0	1.2	2.2	0.5	-1.5
Financial situation satisfaction	1.0	1.3	1.6	1.0	-1.3
Risk taking	1.0	1.4	1.5	-1.2	1.1
Vitamin and mineral supplements	0.9	1.2	1.5	1.0	1.2
Number of incorrect matches in round	0.9	1.5	1.8	1.1	1.4
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.5	0.5	-1.6
Diabetes (self-reported)	0.9	1.4	2.1	0.8	-1.5
Qualifications: A levels/AS levels or equivalent	0.9	1.9	3.2	-1.8	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	2.6	-1.6	0.2
Suffer from ‘nerves’	0.9	1.5	2.0	1.0	1.4
Diabetes diagnosed by doctor	0.9	1.4	1.5	1.2	-1.2
Osteoporosis (self-reported)	0.9	1.1	1.7	1.3	0.7
Number of self-reported non-cancer illnesses	0.9	1.5	2.1	1.5	-1.0
Hearing aid user	0.9	1.1	2.1	1.5	-0.0
Medication: Lisinopril	0.9	1.1	1.6	0.8	-1.3
Ever depressed for a whole week	0.9	1.1	2.0	-1.4	-0.5
Blood White Count	0.8	6.0	6.4	-2.5	2.4
Lung FEV1/FVC ratio	0.8	4.1	8.0	2.8	-0.5
Falls in the last year	0.8	1.1	1.8	0.6	1.3
Peak expiratory flow (PEF)	0.8	1.8	3.1	-1.8	-0.6
Average weekly red wine intake	0.8	1.2	2.1	0.6	-1.4
Commuting to job workplace: Walk	0.8	0.8	1.7	1.3	0.0
Depression (Nagel 2018)	0.7	1.0	1.7	-1.3	-0.6
Rheumatoid Arthritis	0.7	0.9	1.6	-0.5	-1.3
Blood Red Count	0.7	6.8	10.0	1.9	3.2
Hand grip strength (right)	0.7	1.9	3.2	-1.8	0.8
Multivitamins +/- minerals	0.7	0.9	0.9	-0.9	-0.9
Alcohol intake versus 10 years previously	0.7	1.0	1.9	-0.3	1.4
Pulse wave Arterial Stiffness index	0.7	0.9	1.6	-0.4	-1.3
Comparative body size at age 10	0.7	1.9	2.2	-1.5	-1.3
Pulse wave peak to peak time	0.7	0.8	1.5	-0.2	1.2
Medication: Blood pressure	0.7	1.3	1.9	0.8	-1.4
Angina (self-reported)	0.7	0.9	1.8	0.3	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	1.7	0.2	1.3
Depressed Affect (Nagel 2018)	0.6	1.2	2.4	-0.3	-1.5
Sensitivity / hurt feelings	0.6	1.0	1.2	0.9	1.1
Angina	0.6	0.8	1.5	0.1	-1.2
Average weekly fortified wine intake	0.6	0.7	1.3	-0.4	1.1
Taking other prescription medications	0.6	0.9	1.2	0.8	-1.1
Chronic bronchitis/emphysema (father)	0.6	0.7	0.8	-0.8	-0.9
High blood pressure (mother)	0.6	0.8	1.7	1.3	0.1
Pulse rate	0.6	1.0	1.4	-1.2	0.7
Pulse wave reflection index	0.6	0.8	1.5	-0.3	-1.2
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	1.9	-1.4	-0.3
Emphysema/chronic bronchitis	0.6	0.7	1.2	-1.1	0.4
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.3	-1.1	0.4
Mood swings	0.6	1.1	1.9	-0.6	-1.4
Medication: Gliclazide	0.6	0.6	0.8	0.7	-0.9
Medication: Bendroflumethiazide	0.6	0.9	1.2	1.1	-0.7
Impedance of whole body	0.6	3.2	6.0	2.4	-0.7
Hand grip strength (left)	0.5	1.4	1.5	-1.2	1.2
Average weekly spirits intake	0.5	0.7	1.1	0.5	1.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.1	1.0	-0.3
Financial difficulties in last 2 years	0.5	0.7	1.1	-1.1	0.4
Fluid intelligence score	0.5	1.1	2.1	-1.5	-0.3
Number of live births	0.5	0.7	1.2	1.1	-0.5
Breastfed as a baby	0.5	0.7	1.2	-1.1	-0.3
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	1.1	-1.1	-0.9
Medication: Amlodipine	0.5	0.7	1.3	1.1	-0.5
Exposure to tobacco smoke outside home	0.5	0.7	1.0	1.0	-0.6
Wheeze or whistling in the chest in last year	0.5	0.9	1.6	0.5	1.3
Medication: Omeprazole	0.5	0.6	0.6	-0.8	-0.7
Tinnitus: Yes, now most or all of the time	0.5	0.5	0.6	0.6	0.8
Average weekly beer plus cider intake	0.5	0.7	1.4	0.3	1.2
Diastolic blood pressure, automated reading	0.5	1.6	3.0	1.7	-0.5
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.3	-0.0	-1.1
Schizophrenia vs Biploar Disorder	0.4	0.5	0.5	0.7	-0.6
Major Depression (MDD)	0.4	0.5	0.7	0.8	0.5
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.5	-0.6	-1.2
Coronary Artery Disease (CAD)	0.4	0.5	0.8	-0.9	-0.4
Fasting Glucose	0.4	0.4	0.5	0.6	-0.7
Lupus	0.4	0.6	1.2	1.1	-0.1
Heel T-Score	0.4	3.0	4.6	1.2	-2.1
Lung FVC	0.4	2.2	4.1	-2.0	-0.5
Diabetes (father)	0.4	0.4	0.5	0.7	0.6
Current tobacco smoking	0.4	0.7	1.0	0.7	-1.0
Alcohol usually taken with meals	0.4	0.6	1.3	-0.0	-1.1
Illnesses of siblings	0.4	0.6	1.1	-1.1	0.1
Worrier / anxious feelings	0.4	0.8	1.2	0.5	1.1
Tense / ‘highly strung’	0.4	0.6	1.0	-1.0	0.5
Birth weight of first child	0.4	0.8	1.4	-1.2	-0.4
Number of full brothers	0.4	0.5	0.8	0.6	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	0.6	-0.7	0.6
Health satisfaction	0.4	0.5	0.8	-0.9	-0.5
Medication: Seretide 50 evohaler	0.4	0.4	0.8	-0.2	0.9
Number of full sisters	0.4	0.5	1.0	-0.0	1.0
Knee pain experienced in last month	0.4	0.7	1.3	-1.1	0.2
Mother’s age at death	0.4	0.5	0.9	-0.9	0.2
Medication: Paracetamol	0.4	0.7	1.4	1.2	-0.0
Fractured/broken bones in last 5 years	0.4	0.5	0.8	0.9	0.5
Myopia	0.4	0.5	1.0	1.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	0.6	-0.5	-0.8
Pain experienced in last month	0.4	0.7	1.5	1.2	0.1
Basal cell carcinoma (self-reported)	0.4	0.5	0.9	0.2	0.9
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.0	-1.0	0.0
Worry (Nagel 2018)	0.3	0.7	1.3	0.2	1.1
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.5	-0.7	0.6
Ulcerative Colitis	0.3	0.4	0.4	0.6	0.6
Relative age of first facial hair	0.3	0.6	1.0	-0.5	1.0
Medication for hormone replacement therapy	0.3	0.4	0.4	-0.7	-0.6
Hearing difficulty/problems with background noise	0.3	0.4	0.8	-0.9	0.2
Had menopause	0.3	0.3	0.4	-0.5	0.6
Heart attack	0.3	0.4	0.9	0.1	-0.9
Medication: Lansoprazole	0.3	0.3	0.3	-0.6	0.6
Blood clot in the leg (DVT)	0.3	0.4	0.7	-0.9	-0.0
Eye problems/disorders: None of the above	0.3	0.3	0.3	-0.5	-0.6
Alcohol intake frequency.	0.3	0.7	1.3	0.3	1.1
Family relationship satisfaction	0.3	0.4	0.5	0.6	-0.7
Supplements: Vitamin C	0.3	0.4	0.6	-0.8	-0.3
Smoking status: Current	0.3	0.4	0.5	0.6	-0.7
Crohns Disease (2017)	0.2	0.4	0.7	-0.9	0.0
Ulcerative Colitis (UC)	0.2	0.4	0.8	0.3	0.9
Reaction Time	0.2	0.3	0.5	0.3	0.7
Ovarian Cancer	0.2	0.3	0.3	-0.5	0.5
Crohns Disease (2012)	0.2	0.3	0.7	-0.8	0.0
HbA1C	0.2	0.2	0.4	0.0	0.6
Primary Biliary Cirrhosis	0.2	0.3	0.5	0.7	0.2
Smoking Status	0.2	0.5	0.9	0.1	-1.0
Respiratory disease	0.2	0.4	0.7	-0.9	-0.2
Neuroticism	0.2	0.4	0.8	0.9	0.1
Hearing difficulty/problems: Yes	0.2	0.3	0.5	0.7	0.3
Age when periods started (menarche)	0.2	0.4	0.6	0.8	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	0.4	-0.6	-0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.3	0.5	0.3
Medication: Levothyroxine sodium	0.2	0.4	0.7	-0.2	-0.8
Neuroticism score	0.2	0.4	0.7	0.3	-0.8
Lung cancer (father)	0.2	0.3	0.5	-0.7	0.1
Illnesses of mother	0.2	0.2	0.3	-0.4	0.5
Length of working week for main job	0.2	0.2	0.5	0.7	0.0
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.3	-0.6	-0.3
High blood pressure (siblings)	0.2	0.3	0.5	0.7	-0.2
Number of children fathered	0.2	0.3	0.3	0.5	0.5
Overall health rating	0.2	0.5	0.8	0.5	0.9
Illnesses of father: Heart disease	0.2	0.3	0.4	0.5	-0.6
Wears glasses or contact lenses	0.2	0.2	0.4	0.7	-0.1
Ever smoked	0.2	0.3	0.7	0.2	0.8
Irritability	0.2	0.4	0.8	0.2	-0.9
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.4	-0.6	-0.4
Neuroticism (Nagel 2018)	0.1	0.2	0.3	0.2	-0.5
Alzheimer’s Disease (in mother)	0.1	0.1	0.3	-0.0	0.5
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	0.2	0.6
Hair Pigment	0.1	2.3	2.4	-1.5	-1.5
Tanning	0.1	0.9	1.8	-1.4	0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	-0.4	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.1	-0.4	-0.3
Nervous feelings	0.1	0.3	0.5	0.7	0.3
Had other major operations	0.1	0.1	0.2	0.5	-0.1
Happiness	0.1	0.1	0.2	-0.5	0.0
Impedance of arm (left)	0.1	0.6	1.0	1.0	-0.3
Glaucoma (self-reported)	0.1	0.1	0.3	-0.1	0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.3	-0.6	0.2
Neck or shoulder pain in last month	0.1	0.1	0.2	0.4	-0.3
Mean time to correctly identify matches	0.1	0.3	0.4	0.6	0.3
Chest pain or discomfort	0.1	0.1	0.1	-0.3	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.1	0.3	-0.2
Smoking status: Previous	0.1	0.1	0.3	-0.5	-0.1
Ever had bowel cancer screening	0.1	0.1	0.2	0.5	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.2	0.2	0.5	0.3
Asthma (self-reported)	0.1	0.1	0.2	-0.4	-0.2
Illnesses of father: None of the above (group 1)	0.1	0.1	0.1	-0.3	0.3
Miserableness	0.1	0.1	0.2	0.4	0.1
Ever taken oral contraceptive pill	0.1	0.2	0.3	0.0	0.6
Number of operations (self-reported)	0.1	0.2	0.3	-0.5	0.1
Unable to work because of sickness or disability	0.1	0.1	0.2	-0.0	0.4
Pack years of smoking	0.1	0.1	0.2	-0.0	0.5
Breast Cancer	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Pack years adult smoking proportion	0.0	0.0	0.0	0.2	0.2
Fed-up feelings	0.0	0.1	0.1	-0.1	-0.4
Past tobacco smoking	0.0	0.0	0.1	0.1	-0.3
Hair/balding pattern: Pattern 2	0.0	0.1	0.1	-0.3	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	0.1	-0.4
Impedance of arm (right)	0.0	0.2	0.3	0.2	-0.5
Asthma	0.0	0.1	0.1	-0.3	-0.1
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	-0.1	-0.4
Ever highly irritable/argumentative for 2 days	0.0	0.1	0.1	0.1	-0.3
Loud music exposure frequency	0.0	0.0	0.0	0.1	0.2
Headache pain in last month	0.0	0.0	0.0	0.1	0.2
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.1	-0.0	0.2
Leg pain on walking	0.0	0.0	0.1	-0.3	0.1
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	0.2	0.1
Long-standing illness, disability or infirmity	0.0	0.1	0.1	0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.1	-0.0	0.2
Eye problems/disorders: Glaucoma	0.0	0.0	0.1	0.1	0.3
Illnesses of father: High blood pressure	0.0	0.0	0.0	0.1	0.2
Alcohol drinker status: Previous	0.0	0.1	0.1	-0.3	0.2

Hub : Genes

RSRC2

Models

Trait associations