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chr11:1,213,806-2,705,175

Best TWAS P=1.03e-20 · Best GWAS P=3.48e-23 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	TNNT3	0.21	-0.01	enet	17	0.00	6.4e-01	-2.6	-7.2	4.1e-13	-0.30	0.05	0.06	TRUE
2	GTEx	Artery Aorta	MRPL23-AS1	0.22	0.07	enet	10	0.12	2.9e-07	6.7	6.0	2.1e-09	0.45	0.97	0.01	FALSE
3	GTEx	Brain Caudate basal ganglia	MRPL23-AS1	0.26	0.07	enet	11	0.10	6.3e-04	3.1	5.5	3.3e-08	0.41	0.24	0.06	FALSE
4	GTEx	Brain Cerebellum	MRPL23-AS1	0.25	0.14	enet	12	0.18	6.8e-06	4.8	5.3	1.3e-07	0.46	0.27	0.25	FALSE
5	GTEx	Brain Frontal Cortex BA9	MRPL23-AS1	0.36	0.23	lasso	3	0.21	3.8e-06	6.7	6.7	2.2e-11	0.49	0.34	0.31	FALSE
6	GTEx	Cells Transformed fibroblasts	LSP1	0.21	0.04	enet	28	0.06	3.4e-05	9.9	7.4	1.6e-13	0.72	0.00	1.00	TRUE
7	GTEx	Colon Sigmoid	MRPL23-AS1	0.39	0.13	lasso	6	0.23	9.8e-09	4.8	5.3	1.1e-07	0.37	0.92	0.01	FALSE
8	GTEx	Esophagus Muscularis	MRPL23-AS1	0.21	0.07	lasso	4	0.10	1.8e-06	4.8	5.3	1.3e-07	0.44	0.93	0.02	FALSE
9	GTEx	Nerve Tibial	MRPL23-AS1	0.18	0.11	lasso	4	0.16	1.2e-11	5.0	5.4	7.0e-08	0.43	1.00	0.00	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	TNNT3	0.33	0.16	lasso	7	0.17	2.0e-09	8.9	9.1	7.6e-20	0.91	0.00	1.00	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	MRPL23-AS1	0.33	0.19	enet	30	0.21	9.5e-12	5.0	5.6	1.8e-08	0.37	1.00	0.00	FALSE
12	GTEx	Skin Sun Exposed Lower leg	TNNT3	0.63	0.02	lasso	20	0.00	3.5e-01	-4.8	5.6	2.1e-08	0.38	0.05	0.05	FALSE
13	GTEx	Skin Sun Exposed Lower leg	MRPL23-AS1	0.19	0.19	enet	9	0.21	5.3e-17	4.8	5.9	3.7e-09	0.45	1.00	0.00	FALSE
14	NTR	Blood	TNNT3	0.04	0.02	blup	461	0.02	4.3e-06	7.3	-5.6	2.5e-08	-0.66	0.09	0.91	FALSE
15	YFS	Blood	TNNT3	0.02	0.02	lasso	3	0.01	1.9e-05	8.9	-7.7	1.1e-14	-0.81	0.03	0.96	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LSP1	0.12	0.08	lasso	5	0.10	5.0e-11	-8.8	-9.3	1.0e-20	-0.60	0.62	0.38	TRUE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	LSP1	0.06	0.04	enet	6	0.04	3.1e-05	7.7	7.0	3.5e-12	0.11	0.67	0.02	FALSE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC100133545	0.03	0.01	blup	49	0.01	1.1e-02	5.0	6.0	1.6e-09	0.39	0.00	0.84	FALSE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LSP1	0.07	0.03	lasso	4	0.03	2.4e-04	7.7	-9.2	2.2e-20	-0.35	0.09	0.25	TRUE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TNNI2	0.11	0.09	lasso	2	0.08	4.1e-06	7.7	-7.7	1.3e-14	-0.19	0.64	0.02	TRUE