TWAS hub - MRPL23-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.210	0.0470	1.3e-08	0.119	NA	0.157	NA	0.164	6.0e-10	NA	8.2e-13	NA	2.1e-13
2	GTEx	Adipose Visceral Omentum	0.296	0.0720	1.2e-06	0.117	NA	0.146	NA	-0.005	1.2e-06	NA	5.3e-08	NA	9.2e-01
3	GTEx	Artery Aorta	0.216	0.0630	6.3e-05	0.067	NA	0.123	NA	0.104	1.5e-04	NA	2.9e-07	NA	2.4e-06
4	GTEx	Artery Tibial	0.269	0.0540	6.2e-11	0.104	NA	0.174	NA	0.187	1.7e-08	NA	1.4e-13	NA	1.5e-14
5	GTEx	Brain Caudate basal ganglia	0.263	0.0930	2.9e-03	0.069	NA	0.105	NA	0.096	4.8e-03	NA	6.3e-04	NA	1.1e-03
6	GTEx	Brain Cerebellum	0.251	0.0860	2.9e-03	0.144	NA	0.176	NA	0.168	4.9e-05	NA	6.8e-06	NA	1.1e-05
7	GTEx	Brain Frontal Cortex BA9	0.358	0.1039	7.9e-04	0.234	NA	0.124	NA	0.206	6.9e-07	NA	3.6e-04	NA	3.8e-06
8	GTEx	Brain Nucleus accumbens basal ganglia	0.246	0.1020	1.0e-02	0.073	NA	-0.006	NA	0.026	5.2e-03	NA	4.9e-01	NA	6.8e-02
9	GTEx	Breast Mammary Tissue	0.296	0.0690	7.6e-07	0.154	NA	0.165	NA	0.187	2.5e-08	NA	7.7e-09	NA	6.4e-10
10	GTEx	Breast Mammary Tissue (Male)	0.344	0.1161	2.6e-03	0.021	NA	0.088	NA	0.067	1.0e-01	NA	4.5e-03	NA	1.2e-02
11	GTEx	Breast Mammary Tissue (Female)	0.241	0.1058	2.4e-02	0.060	NA	0.000	NA	0.007	7.5e-03	NA	3.3e-01	NA	1.9e-01
12	GTEx	Colon Sigmoid	0.393	0.0920	3.4e-05	0.129	NA	0.210	NA	0.232	2.6e-05	NA	5.7e-08	NA	9.8e-09
13	GTEx	Colon Transverse	0.131	0.0520	8.5e-03	0.026	NA	0.033	NA	0.026	2.0e-02	NA	1.0e-02	NA	2.1e-02
14	GTEx	Esophagus Mucosa	0.095	0.0400	6.6e-03	0.096	NA	0.056	NA	0.077	5.9e-07	NA	1.2e-04	NA	7.8e-06
15	GTEx	Esophagus Muscularis	0.207	0.0600	3.5e-05	0.066	NA	0.087	NA	0.097	7.9e-05	NA	6.0e-06	NA	1.8e-06
16	GTEx	Heart Atrial Appendage	0.168	0.0640	5.2e-03	0.059	NA	0.043	NA	0.053	1.2e-03	NA	5.2e-03	NA	2.2e-03
17	GTEx	Lung	0.291	0.0637	2.0e-08	0.090	NA	0.117	NA	0.121	2.1e-07	NA	3.1e-09	NA	1.6e-09
18	GTEx	Nerve Tibial	0.185	0.0503	1.7e-05	0.114	NA	0.162	NA	0.163	2.0e-08	NA	1.5e-11	NA	1.2e-11
19	GTEx	Skin Not Sun Exposed Suprapubic	0.326	0.0620	9.0e-08	0.187	NA	0.210	NA	0.165	1.6e-10	NA	9.5e-12	NA	2.3e-09
20	GTEx	Skin Sun Exposed Lower leg	0.194	0.0400	7.9e-10	0.194	NA	0.207	NA	0.201	6.2e-16	NA	5.3e-17	NA	1.7e-16
21	GTEx	Stomach	0.154	0.0600	6.6e-03	0.059	NA	0.008	NA	0.045	8.6e-04	NA	1.2e-01	NA	3.3e-03
22	GTEx	Testis	0.265	0.0650	3.0e-05	0.225	NA	0.158	NA	0.197	2.4e-10	NA	1.7e-07	NA	4.0e-09
23	GTEx	Thyroid	0.205	0.0470	2.7e-07	0.155	NA	0.163	NA	0.166	5.9e-12	NA	1.7e-12	NA	1.0e-12
24	GTEx	Uterus	0.381	0.1050	1.1e-03	0.077	NA	0.066	NA	0.044	1.2e-02	NA	1.9e-02	NA	4.5e-02
25	GTEx	Whole Blood	0.076	0.0290	3.8e-03	0.076	NA	0.049	NA	0.056	1.7e-07	NA	2.5e-05	NA	6.1e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	25
Breast Cancer	22.2	53.4	71.7	7.4	7.1	8.5	8.2	7.3	7.8	8.2	7.3	6.7	4.4	6.6	7.6	7.8	6.5	8.0	7.2	7.7	8.2	8.0	8.4	7.0	6.7	8.2	6.9
Systolic Blood Pressure	14.4	71.9	132.2	7.3	6.5	10.3	8.9	7.7	9.5	11.5	9.2	8.7	7.6	8.3	9.8	10.2	6.4	9.9	7.1	8.0	9.8	11.2	10.7	6.5	4.7	7.7	5.5
Medication: Blood pressure	12.0	22.8	36.4	4.6	4.3	5.9	5.3	5.3	5.3	6.0	4.8	5.1	2.1	5.2	4.9	4.6	4.6	5.4	4.8	4.8	5.4	5.7	5.9	3.9	3.1	4.5	3.5
Hypertension (Self-reported)	8.7	24.1	46.4	4.4	3.6	6.3	5.3	5.8	5.6	6.8	5.2	5.4	2.3	5.3	5.6	4.7	4.4	5.5	4.8	4.8	5.7	5.8	6.2	3.7	2.5	4.2	3.1
Medication: Bendroflumethiazide	8.5	12.9	21.6	3.3	2.7	4.6	3.6	4.4	4.0	4.6	4.3	4.2	2.0	4.0	4.4	3.6	3.8	4.4	3.5	3.4	4.0	3.7	4.5	2.6	1.5	2.5	1.7
High blood pressure	7.8	21.6	44.8	4.1	3.3	6.0	5.0	5.5	5.3	6.7	5.1	5.0	1.8	4.8	5.3	4.5	4.2	5.3	4.5	4.6	5.4	5.6	5.9	3.4	2.5	3.8	3.0
Medication: Lisinopril	7.6	9.8	15.8	3.2	3.3	3.8	3.4	3.1	3.5	3.3	3.1	3.9	2.5	4.0	3.6	2.4	3.1	3.6	3.1	3.0	3.7	3.0	3.7	2.4	1.5	3.0	2.1
Medication: Amlodipine	7.3	10.2	23.0	2.8	2.6	4.1	3.4	3.5	3.6	4.8	3.5	3.0	1.7	3.0	3.4	3.8	2.4	3.9	2.8	3.1	3.7	3.6	4.2	2.6	2.0	2.6	2.4
High blood pressure (mother)	7.1	10.0	18.7	2.7	2.1	3.6	3.3	3.6	4.2	4.0	3.3	3.4	2.9	3.3	3.6	2.8	2.0	3.5	2.7	3.0	3.2	4.3	3.9	2.6	2.3	3.5	2.2
Systolic blood pressure, automated reading	6.7	19.4	41.7	3.3	2.5	5.5	4.3	4.5	5.3	6.5	5.3	3.9	4.3	3.7	5.4	5.9	2.9	5.3	3.2	3.9	5.2	6.2	5.8	2.7	1.9	3.6	2.2
Friendships satisfaction	6.2	7.6	12.7	3.1	2.8	3.2	3.1	3.6	2.7	3.3	2.4	2.5	0.9	2.5	2.4	1.9	3.2	2.9	3.2	3.2	2.9	2.0	3.0	3.2	2.8	2.7	3.0
Cardiovascular Disease	5.9	19.4	43.0	3.7	3.5	5.6	4.8	3.9	5.1	6.6	4.4	5.0	2.7	5.0	5.1	4.4	3.2	4.9	3.8	3.9	5.4	6.5	5.8	2.9	1.8	3.5	2.4
Vascular/heart problems diagnosed by doctor	5.7	15.4	33.6	-3.3	-2.6	-5.1	-4.2	-4.7	-4.6	-5.8	-4.6	-4.3	-1.5	-4.1	-4.7	-3.5	-3.4	-4.5	-3.7	-3.9	-4.6	-4.5	-5.1	-2.8	-1.9	-3.1	-2.4
Illnesses of mother	5.4	6.7	13.5	-2.2	-1.4	-3.0	-2.8	-2.5	-3.2	-3.0	-2.9	-3.3	-2.3	-3.2	-3.0	-2.6	-1.8	-2.9	-2.0	-2.5	-2.9	-3.7	-3.2	-1.5	-1.3	-2.9	-1.5
Medication for cholesterol	5.2	8.0	16.2	-2.7	-2.2	-3.4	-3.2	-3.0	-3.2	-4.0	-2.9	-2.8	-0.9	-3.1	-2.2	-2.5	-2.3	-2.9	-2.8	-2.9	-3.1	-4.0	-3.5	-2.2	-2.2	-3.1	-2.3
Supplements: Zinc	4.8	5.2	10.5	2.4	1.6	2.3	2.5	3.2	3.2	2.4	2.3	1.7	1.2	1.5	1.8	1.1	2.3	2.2	2.6	2.8	2.2	2.2	2.2	2.1	2.8	2.6	2.9
Loud music exposure frequency	4.7	5.1	9.6	1.9	1.6	2.7	2.4	2.3	2.5	2.9	2.6	2.3	3.1	2.2	2.4	2.4	1.7	2.5	1.9	2.3	2.6	2.3	2.9	1.6	1.6	2.1	1.8
Number of incorrect matches in round	4.6	7.6	11.6	3.4	2.7	2.8	3.1	3.4	2.6	1.6	2.4	2.8	1.6	2.7	2.8	2.6	3.3	2.9	3.3	3.2	2.8	2.1	2.5	2.9	2.7	3.1	3.1
Illnesses of father: High blood pressure	4.6	5.7	9.7	2.5	2.2	2.5	2.8	3.1	2.6	1.9	1.5	2.6	1.4	2.5	2.7	2.2	2.0	2.5	2.4	2.3	2.8	3.1	2.6	2.2	1.8	3.0	2.1
Medication: Atenolol	4.4	5.6	8.8	2.2	1.3	2.9	2.5	2.8	3.0	2.8	2.6	2.9	1.2	2.7	2.4	1.8	2.5	2.8	2.5	2.4	2.3	2.2	2.8	2.2	1.6	2.3	1.8
High blood pressure (siblings)	4.2	6.1	11.1	2.4	2.1	3.0	2.6	2.8	3.0	3.3	3.0	2.5	1.6	2.6	2.6	2.5	2.3	2.9	2.4	2.5	2.5	2.4	3.0	2.0	1.9	2.1	1.9
Eye problems/disorders: None of the above	4.1	4.7	7.9	2.3	1.8	2.3	2.4	2.1	2.7	1.9	2.1	2.8	1.9	2.6	2.3	1.3	2.1	2.4	2.3	2.4	2.1	1.5	2.3	2.2	1.9	2.8	2.0
Breast cancer (self-reported)	4.0	4.8	10.1	-2.4	-1.5	-2.1	-2.5	-2.1	-2.4	-1.8	-1.7	-2.0	-1.4	-2.1	-1.9	-2.8	-1.5	-2.1	-2.1	-2.3	-2.0	-3.2	-2.2	-2.3	-2.5	-2.8	-2.6
Age when periods started (menarche)	3.8	9.2	13.2	-3.2	-3.3	-3.5	-3.3	-3.6	-3.6	-2.9	-2.9	-2.6	-2.1	-2.5	-3.1	-3.2	-3.2	-3.4	-3.2	-3.1	-3.6	-3.1	-3.5	-2.9	-2.5	-2.8	-2.7
Coronary Artery Disease (CAD)	3.7	4.4	8.4	2.2	2.2	2.3	2.3	2.1	2.2	0.0	2.0	2.5	1.0	2.2	2.8	2.1	1.9	2.6	1.9	2.1	2.5	2.9	2.3	2.3	1.4	1.9	1.6
Type 2 Diabetes (T2D) (2012)	3.7	4.3	7.1	2.4	1.4	1.9	2.3	2.4	2.4	1.0	1.6	2.3	2.5	2.2	2.5	2.6	1.6	2.1	2.0	2.1	2.0	1.9	1.9	1.9	1.6	2.7	2.1
Trunk fat percentage	3.5	13.9	23.7	-3.7	-4.6	-4.2	-4.0	-4.1	-4.5	-3.8	-3.3	-3.0	-1.3	-3.0	-3.4	-4.9	-3.8	-4.0	-4.1	-3.8	-4.0	-4.2	-4.1	-3.4	-3.5	-3.6	-3.7
Chronic bronchitis/emphysema (father)	3.4	4.0	10.3	-2.2	-1.7	-1.9	-2.3	-2.1	-1.8	-1.8	-1.0	-1.7	-1.4	-1.5	-1.5	-1.8	-1.2	-2.0	-1.8	-2.1	-1.9	-3.2	-2.0	-2.2	-2.6	-3.0	-2.5
Exposure to tobacco smoke outside home	3.4	4.5	10.8	-1.9	-1.7	-2.4	-2.3	-1.8	-2.2	-1.9	-2.1	-2.6	-2.0	-2.4	-2.3	-1.9	-2.0	-2.4	-2.1	-2.1	-2.6	-3.3	-2.5	-1.8	-1.4	-1.9	-1.4
Medication: Blood pressure	3.3	5.9	11.2	1.9	1.5	3.0	2.5	2.5	2.8	3.4	2.8	3.2	1.4	3.1	3.3	2.4	1.9	2.9	2.1	2.1	2.8	3.0	3.2	1.5	0.4	1.6	0.9
Arm fat percentage (left)	3.2	12.8	18.8	-3.9	-4.3	-3.9	-3.9	-3.8	-4.0	-2.8	-3.0	-3.0	-1.3	-3.2	-3.1	-3.9	-4.2	-3.8	-4.3	-3.8	-3.8	-3.6	-3.7	-3.7	-3.5	-3.8	-3.7
Respiratory disease	3.1	7.0	12.2	-3.2	-3.4	-3.0	-3.0	-2.3	-2.4	-1.6	-1.3	-3.2	-1.2	-2.8	-2.3	-1.9	-3.5	-3.0	-3.4	-2.8	-3.0	-2.2	-2.6	-3.1	-2.6	-2.9	-2.5
Falls in the last year	3.1	4.2	6.7	2.5	1.8	2.2	2.3	2.6	2.5	1.5	2.1	1.7	0.9	1.9	1.6	1.3	2.6	2.1	2.6	2.6	1.9	1.5	2.1	2.2	2.5	1.8	2.5
Medication: Seretide 50 evohaler	3.0	3.4	5.4	-2.0	-2.0	-1.9	-2.0	-1.9	-2.1	-1.2	-1.3	-2.3	-1.4	-1.9	-2.2	-1.9	-1.7	-2.2	-1.8	-1.9	-1.8	-2.1	-1.9	-1.7	-1.7	-2.2	-1.8
Wheeze or whistling in the chest in last year	2.9	5.1	11.4	-2.5	-3.4	-2.6	-2.5	-1.9	-1.9	-1.9	-1.7	-2.6	-1.4	-2.8	-2.1	-1.9	-2.5	-2.3	-2.5	-2.1	-2.6	-3.0	-2.4	-2.4	-1.6	-2.2	-1.6
Medication: Ramipril	2.8	3.6	6.8	2.0	1.2	2.2	2.2	2.6	1.9	1.5	2.2	2.3	0.1	2.6	2.0	1.2	2.3	2.0	2.4	2.1	2.0	1.9	2.0	2.1	0.9	1.4	1.4
Peak expiratory flow (PEF)	2.8	6.6	11.9	-2.7	-1.2	-3.0	-2.7	-2.5	-3.5	-3.3	-2.6	-1.5	-2.1	-1.4	-2.3	-2.9	-2.3	-2.9	-2.5	-2.9	-2.6	-1.6	-2.9	-2.6	-2.9	-3.0	-3.3
Primary Biliary Cirrhosis	2.7	3.8	7.7	2.2	1.5	2.0	2.3	1.8	2.0	1.4	1.6	1.8	2.4	2.1	1.2	1.7	2.1	1.7	2.3	2.3	2.1	1.0	2.0	2.4	2.0	2.8	2.1
Arm fat percentage (right)	2.7	10.7	16.1	-3.6	-4.0	-3.5	-3.6	-3.5	-3.7	-2.4	-2.7	-2.7	-0.9	-2.9	-2.8	-3.6	-3.9	-3.5	-4.0	-3.5	-3.5	-3.3	-3.3	-3.5	-3.3	-3.5	-3.5
Mean Putamen Volume	2.6	3.0	5.8	1.9	2.3	1.8	1.9	2.3	1.4	1.1	1.3	1.8	0.8	1.8	1.6	0.6	2.1	1.7	2.3	1.9	1.8	1.4	1.6	2.4	1.4	1.6	1.8
Happiness	2.6	3.2	6.2	2.1	1.2	2.1	1.9	2.0	2.3	1.9	1.7	2.0	0.8	2.0	1.6	0.8	2.5	2.0	2.3	2.0	1.7	0.9	1.9	2.1	1.5	1.6	1.7
Trunk fat mass	2.4	10.3	21.5	-2.9	-3.7	-3.6	-3.3	-3.3	-3.8	-3.2	-3.1	-2.8	-1.4	-2.8	-3.0	-4.6	-3.1	-3.5	-3.3	-3.1	-3.5	-4.0	-3.6	-2.5	-2.6	-3.4	-2.9
Body fat percentage	2.4	9.4	17.0	-3.2	-4.1	-3.4	-3.3	-3.2	-3.6	-2.7	-2.4	-2.5	-0.8	-2.5	-2.5	-4.0	-3.4	-3.3	-3.6	-3.1	-3.3	-3.3	-3.2	-2.9	-3.0	-3.0	-3.1
Irritability	2.4	4.0	6.6	2.3	2.1	2.4	2.4	1.5	2.4	1.4	1.2	2.3	0.9	2.0	2.1	1.4	2.3	2.5	2.1	2.0	2.6	2.1	2.4	2.0	1.7	1.9	1.9
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.5	5.1	-1.8	-0.8	-1.5	-1.8	-1.8	-2.3	-1.1	-1.5	-1.1	-0.6	-1.2	-1.4	-1.4	-1.8	-1.4	-2.0	-2.0	-1.4	-1.5	-1.3	-1.7	-2.1	-2.1	-2.0
Medication: Co-codamol	2.2	2.6	5.8	-1.7	-1.6	-1.8	-1.6	-1.8	-1.9	-2.1	-1.4	-0.8	0.1	-0.6	-1.4	-2.4	-1.4	-1.7	-1.6	-1.8	-1.3	-1.2	-1.6	-1.4	-2.4	-1.6	-2.2
Illnesses of father: Heart disease	2.2	3.0	8.0	1.9	1.7	1.7	1.9	1.5	1.8	1.2	1.4	1.8	1.0	1.6	2.2	1.4	1.5	1.9	1.6	1.8	2.0	2.8	1.8	2.2	1.4	1.9	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.6	5.7	-1.6	-1.6	-1.9	-1.7	-1.9	-1.4	-1.7	-1.8	-1.4	-2.4	-1.5	-1.7	-1.6	-1.7	-1.7	-1.7	-1.7	-2.0	-1.2	-1.8	-1.4	-1.1	-1.3	-1.1
Mother’s age at death	2.2	2.8	6.7	1.6	1.6	1.6	1.8	1.7	2.2	0.9	1.7	1.8	1.2	1.5	2.0	1.4	1.1	2.0	1.5	1.9	1.6	2.6	1.8	1.5	1.5	2.2	1.6
Stomach or abdominal pain in last month	2.1	2.6	5.8	-1.9	-0.8	-1.8	-1.9	-1.7	-2.4	-1.4	-1.2	-1.1	-2.0	-0.9	-1.5	-2.0	-1.2	-1.8	-1.4	-1.7	-2.1	-0.3	-1.9	-1.5	-1.6	-2.0	-1.9
Ever highly irritable/argumentative for 2 days	2.1	2.5	5.2	1.4	1.2	1.8	1.6	2.3	2.2	1.6	1.5	1.6	2.2	1.6	1.9	0.8	1.6	1.7	1.6	1.6	1.9	2.1	1.8	1.0	0.6	1.1	1.0
Family relationship satisfaction	2.1	2.6	7.7	1.3	1.5	1.9	1.6	1.9	2.3	2.8	1.8	1.5	0.6	1.3	1.4	1.2	1.3	1.8	1.3	1.6	1.7	2.1	2.0	1.6	1.3	1.3	1.3
Fasting Glucose	2.0	2.4	8.8	1.8	0.9	1.0	1.6	1.8	1.2	1.5	1.0	0.4	-1.4	0.3	-0.2	1.5	1.4	0.5	1.9	2.0	0.8	0.4	0.7	2.0	2.9	2.7	3.0
Asthma	2.0	4.0	7.2	-2.5	-2.7	-2.1	-2.3	-1.8	-1.9	-0.9	-1.1	-2.5	-0.4	-2.2	-1.5	-1.4	-2.7	-2.1	-2.6	-2.0	-2.0	-1.9	-1.7	-2.2	-2.2	-2.4	-2.0
Illnesses of siblings: Diabetes	2.0	2.4	5.6	-1.7	-1.6	-1.5	-1.7	-1.2	-1.4	-1.0	-1.1	-1.4	-1.1	-1.3	-1.4	-1.6	-1.5	-1.6	-1.6	-1.7	-1.7	-1.7	-1.5	-2.1	-2.0	-2.4	-1.7
Irritable Bowel Disease (IBD)	1.9	4.5	9.4	2.0	1.7	2.4	2.2	2.8	3.1	3.0	2.6	1.8	1.7	1.9	2.1	1.9	2.1	2.2	2.1	2.4	2.3	1.8	2.3	1.8	1.3	1.9	1.5
Diverticular disease/diverticulitis (self-reported)	1.9	2.2	3.9	-1.9	-0.6	-1.6	-1.8	-1.7	-1.3	-1.0	-1.3	-1.7	-1.4	-1.9	-1.4	-0.6	-1.8	-1.5	-2.0	-1.8	-1.6	-1.4	-1.6	-1.5	-1.2	-1.5	-1.4
Medication: Lansoprazole	1.9	2.2	5.5	-1.5	-1.8	-1.6	-1.7	-1.4	-1.5	-1.4	-1.2	-1.3	-0.6	-1.5	-1.1	-1.3	-1.4	-1.2	-1.5	-1.6	-1.8	-2.4	-1.6	-1.4	-1.4	-1.6	-1.4
Arm fat mass (right)	1.9	7.8	13.3	-2.8	-3.0	-3.0	-3.0	-2.8	-3.2	-2.2	-2.8	-2.6	-1.3	-2.7	-2.5	-3.6	-3.1	-3.0	-3.2	-2.9	-3.0	-3.2	-3.0	-2.5	-2.4	-3.3	-2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	5.0	-1.4	-1.1	-1.6	-1.7	-1.5	-1.5	-1.5	-2.0	-1.1	-0.0	-1.0	-1.1	-2.2	-1.0	-1.2	-1.4	-1.8	-1.8	-2.0	-1.6	-1.2	-1.6	-1.7	-1.7
Waist circumference	1.8	6.5	12.1	-2.7	-2.8	-2.7	-2.8	-2.6	-2.6	-1.7	-2.2	-2.3	-0.9	-2.3	-2.1	-3.0	-3.0	-2.6	-3.1	-2.7	-2.6	-2.5	-2.5	-2.6	-2.6	-3.5	-2.9
Impedance of arm (left)	1.8	8.4	16.6	-2.9	-3.2	-3.4	-3.2	-3.3	-4.1	-4.1	-2.3	-1.8	-0.8	-1.6	-2.6	-3.3	-2.1	-3.1	-2.7	-3.0	-3.5	-3.8	-3.4	-2.5	-3.0	-2.4	-2.8
Medication: Ventolin 100micrograms inhaler	1.8	2.3	3.8	-1.8	-1.6	-1.9	-1.7	-1.1	-1.5	-1.6	-0.6	-1.5	0.9	-1.4	-1.6	-1.6	-1.7	-1.8	-1.6	-1.4	-1.6	-1.9	-1.7	-1.5	-1.3	-1.6	-1.6
Whole body fat mass	1.8	7.4	15.8	-2.5	-3.4	-3.0	-2.8	-2.6	-3.1	-2.4	-2.6	-2.5	-1.2	-2.6	-2.5	-4.0	-2.9	-2.9	-2.9	-2.6	-2.9	-3.3	-3.0	-2.1	-2.1	-2.9	-2.4
Eye problems/disorders: Cataract	1.8	2.1	3.4	-1.5	-1.4	-1.3	-1.5	-1.6	-1.9	-1.2	-1.6	-1.8	-1.2	-1.7	-1.6	-0.8	-1.3	-1.6	-1.5	-1.7	-1.2	-1.5	-1.5	-1.6	-1.3	-1.6	-1.3
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	4.4	1.3	1.7	1.7	1.4	2.0	1.7	2.1	1.9	1.7	0.4	1.7	1.2	0.9	1.9	1.6	1.8	1.7	1.0	0.2	1.6	1.3	1.3	0.7	1.2
Number of full sisters	1.7	2.1	3.1	-1.7	-0.6	-1.6	-1.7	-1.4	-1.6	-0.8	-1.1	-1.5	-1.7	-1.6	-1.1	-0.8	-1.6	-1.6	-1.7	-1.6	-1.7	-1.6	-1.6	-1.7	-1.2	-1.7	-1.4
Emphysema/chronic bronchitis	1.6	1.8	5.9	-1.8	-0.9	-1.1	-1.5	-1.4	-1.1	-0.6	-0.1	-0.6	0.1	-0.7	-0.6	-1.4	-1.3	-1.2	-1.6	-1.5	-0.9	-0.6	-1.0	-2.3	-2.4	-1.9	-2.4
Mineral and other dietary supplements	1.6	2.1	8.8	-1.7	-3.0	-1.3	-1.5	-1.9	-1.0	-0.4	-0.7	-1.5	-0.6	-1.6	-1.1	0.1	-1.6	-1.2	-1.6	-1.5	-1.4	-1.7	-1.1	-2.1	-1.1	-1.7	-1.3
Asthma (self-reported)	1.6	3.1	6.2	-2.2	-2.4	-1.9	-2.0	-1.4	-1.5	-0.8	-0.8	-2.4	-0.3	-2.1	-1.4	-1.3	-2.5	-1.9	-2.3	-1.7	-1.8	-1.9	-1.5	-2.1	-1.8	-2.1	-1.6
Arm fat mass (left)	1.6	6.5	12.1	-2.5	-2.9	-2.8	-2.7	-2.6	-2.9	-2.1	-2.5	-2.2	-1.0	-2.4	-2.2	-3.5	-2.9	-2.7	-2.9	-2.6	-2.8	-3.0	-2.7	-2.1	-2.1	-3.0	-2.4
Crohns Disease (2017)	1.5	3.2	7.2	1.3	1.8	2.1	1.6	2.3	2.6	2.6	2.7	1.4	1.5	1.4	2.1	1.7	1.3	2.1	1.2	1.8	2.1	2.1	2.3	1.0	0.5	1.1	0.7
Migraine (self-reported)	1.5	1.8	5.3	-1.4	-2.3	-1.4	-1.4	-1.3	-0.9	-1.3	-1.6	-1.7	-0.6	-1.7	-1.3	-0.0	-1.3	-1.2	-1.2	-1.5	-1.5	-1.4	-1.5	-1.5	-1.1	-1.6	-1.0
Supplements: Fish oil (including cod liver oil)	1.5	2.0	6.8	1.6	2.6	1.3	1.5	1.7	1.0	0.5	0.8	1.4	0.9	1.5	1.3	0.2	1.6	1.3	1.5	1.6	1.5	1.5	1.2	1.9	1.4	1.8	1.3
Impedance of arm (right)	1.4	6.6	13.6	-2.6	-2.8	-2.9	-2.8	-2.9	-3.7	-3.6	-2.1	-1.3	-0.2	-1.0	-2.2	-3.1	-1.6	-2.7	-2.2	-2.7	-3.1	-3.4	-3.0	-2.3	-2.9	-2.0	-2.7
Chest pain or discomfort	1.4	2.0	4.9	-1.7	-1.1	-1.5	-1.7	-1.4	-1.6	-1.2	-0.4	-0.6	-0.7	-0.3	-1.0	-1.8	-1.1	-1.7	-1.2	-1.3	-1.8	-1.1	-1.5	-1.6	-2.2	-1.9	-2.2
Medication: Levothyroxine sodium	1.3	2.3	3.9	1.6	2.0	1.6	1.7	1.4	1.0	1.1	1.3	1.9	0.9	1.9	1.8	1.9	1.2	1.4	1.3	1.5	2.0	1.8	1.6	1.3	1.0	1.8	1.1
Allergy	1.3	2.9	4.5	2.1	2.1	1.8	1.8	1.6	1.3	1.3	1.4	2.0	1.9	1.8	1.7	2.0	1.9	1.7	1.9	1.7	1.6	1.9	1.6	1.9	1.6	1.4	1.5
Average weekly champagne plus white wine intake	1.3	1.8	6.9	1.1	1.1	1.6	1.3	1.9	1.5	2.1	1.4	0.9	-0.2	0.8	1.6	0.9	0.7	1.5	0.8	1.4	1.5	2.6	1.7	1.0	0.9	1.2	0.9
Prostate Cancer	1.2	1.7	5.7	1.6	-0.1	1.0	1.5	1.6	1.4	0.6	0.8	0.6	1.0	0.5	0.4	1.0	1.5	0.8	1.6	1.8	1.1	1.7	0.9	1.4	2.2	1.9	2.4
Lupus	1.2	1.8	5.7	-1.1	-0.9	-1.5	-1.4	-0.9	-1.3	-1.9	-1.5	-1.2	-2.1	-1.2	-1.6	-0.8	-0.9	-1.4	-1.0	-1.4	-1.6	-2.4	-1.7	-1.1	-0.7	-1.3	-0.9
Relative age of first facial hair	1.2	2.5	5.0	1.6	0.1	1.6	1.6	2.1	1.7	1.3	1.9	1.3	1.8	1.0	1.2	1.8	1.6	1.6	1.6	1.9	1.3	1.2	1.6	1.8	2.2	2.2	1.8
Nervous feelings	1.2	2.3	5.4	1.5	1.2	1.7	1.6	1.5	1.8	1.2	1.8	1.8	1.9	2.0	1.8	0.2	2.3	1.8	1.8	1.7	1.8	0.5	1.6	1.3	0.2	1.3	0.6
Lung cancer (father)	1.2	1.4	4.8	0.6	0.6	1.7	0.9	1.6	1.3	2.2	2.2	0.9	0.8	0.8	1.3	1.7	1.2	1.5	0.9	1.2	1.5	0.4	1.6	0.3	0.1	0.2	0.2
Osteoporosis (self-reported)	1.2	1.5	2.5	1.5	0.9	1.3	1.3	1.0	1.5	1.1	1.3	0.9	1.2	0.9	1.0	1.4	1.1	1.4	1.3	1.4	1.2	1.1	1.2	1.6	1.4	1.1	1.6
Leg fat percentage (left)	1.2	4.2	11.0	-2.5	-3.3	-2.0	-2.2	-1.9	-2.0	-1.0	-0.9	-1.6	-0.2	-1.7	-1.2	-2.7	-2.6	-2.1	-2.8	-2.0	-1.9	-1.6	-1.8	-2.5	-2.5	-2.1	-2.6
Alcohol drinker status: Previous	1.2	1.3	6.5	-0.6	-2.5	-0.9	-0.8	-0.1	-0.8	-0.7	-0.8	-1.2	-2.1	-1.1	-1.6	-1.9	-0.5	-1.4	-0.3	-0.6	-1.3	-1.9	-1.1	-0.5	0.0	-0.9	0.2
Qualifications: A levels/AS levels or equivalent	1.1	2.3	3.8	1.7	1.5	1.6	1.8	1.9	1.8	1.1	1.7	1.7	1.2	1.5	1.4	1.1	1.6	1.4	1.9	1.8	1.7	0.9	1.5	1.5	1.6	1.7	1.6
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	3.3	-0.6	-1.3	-1.3	-0.9	-1.2	-1.2	-1.6	-1.7	-1.1	-1.8	-1.0	-1.7	-1.0	-0.6	-1.1	-0.5	-1.0	-1.4	-1.6	-1.4	-0.0	-0.0	-0.9	0.0
Glaucoma (self-reported)	1.1	1.3	3.4	-1.1	-1.3	-1.5	-1.5	-0.7	-1.2	-1.1	-0.7	-1.4	-1.1	-1.3	-1.3	-0.6	-0.9	-1.3	-1.1	-1.0	-1.8	-1.1	-1.4	-1.1	-0.9	-1.0	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	3.2	1.1	1.4	1.3	1.0	1.8	1.1	1.5	1.5	1.5	0.7	1.8	1.0	-0.3	1.5	1.2	1.4	1.4	0.9	1.4	1.2	0.8	0.3	1.0	0.4
Leg fat mass (left)	1.1	4.1	10.4	-2.0	-2.6	-2.2	-2.1	-1.9	-2.1	-1.5	-1.8	-1.8	-0.7	-1.9	-1.6	-3.2	-2.3	-2.1	-2.4	-2.0	-2.1	-2.3	-2.1	-1.7	-1.8	-2.3	-2.0
Prospective memory result	1.0	1.3	2.4	-1.2	-1.2	-1.3	-1.4	-1.1	-1.3	-1.3	-0.3	-0.5	-0.9	-0.6	-1.1	-0.8	-1.1	-1.0	-1.2	-1.2	-1.6	-0.1	-1.2	-1.5	-1.4	-1.4	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.3	7.7	-1.6	0.4	-1.9	-2.0	-2.2	-2.8	-2.0	-2.5	-1.7	-1.9	-1.7	-1.7	-1.6	-1.0	-1.6	-1.4	-2.0	-1.7	-0.7	-2.1	-1.0	-1.8	-2.8	-2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	2.9	1.6	1.6	1.3	1.4	1.1	1.3	1.4	0.6	1.3	0.2	1.2	0.6	0.2	1.6	1.2	1.7	1.5	1.0	0.8	1.1	1.6	1.6	1.4	1.7
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	4.5	-0.8	-0.9	-1.6	-1.2	-1.3	-1.4	-1.7	-1.7	-2.1	-0.6	-2.0	-2.1	-0.9	-0.9	-1.5	-0.9	-0.9	-1.6	-1.7	-1.7	-0.5	0.6	-0.3	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	3.6	0.8	1.1	1.0	1.2	1.9	1.7	1.0	1.5	0.6	0.7	0.7	1.2	1.2	0.5	0.8	0.8	1.2	1.2	1.3	1.1	0.5	1.2	1.6	1.1
Leg fat mass (right)	1.0	3.9	9.9	-1.9	-2.5	-2.2	-2.1	-1.7	-2.1	-1.6	-1.7	-1.6	-0.6	-1.8	-1.5	-3.1	-2.2	-2.1	-2.2	-1.9	-2.1	-2.3	-2.1	-1.6	-1.7	-2.2	-1.9
Had major operations	1.0	1.2	3.1	1.1	1.4	1.3	1.1	1.1	0.8	1.8	0.7	0.5	-0.2	0.5	0.6	1.0	1.1	1.1	1.1	1.2	1.0	1.1	1.1	1.5	1.3	1.2	1.4
Risk taking	1.0	1.5	5.4	-1.1	-1.6	-1.4	-1.0	-1.0	-0.7	-0.7	-0.9	-1.7	-2.3	-1.8	-1.6	-0.9	-1.7	-1.4	-1.2	-0.9	-1.4	-1.1	-1.3	-0.9	0.0	-0.8	0.1
Depression (Nagel 2018)	0.9	1.3	2.9	1.2	1.4	1.4	1.1	1.0	0.9	1.5	1.1	1.3	-0.3	1.5	1.3	-0.5	1.7	1.5	1.3	1.3	1.0	0.2	1.3	1.5	0.7	0.7	0.8
Illnesses of siblings	0.9	1.2	4.8	-0.3	-0.3	-1.3	-0.7	-1.0	-1.2	-2.2	-1.9	-1.4	-1.7	-1.5	-1.5	-1.0	-0.4	-1.2	-0.4	-0.6	-1.0	-0.9	-1.5	0.3	0.6	-0.2	0.4
Leg fat percentage (right)	0.9	3.2	8.3	-2.1	-2.9	-1.8	-1.9	-1.6	-1.8	-1.1	-0.7	-1.2	0.0	-1.2	-0.9	-2.7	-2.1	-1.9	-2.3	-1.7	-1.7	-1.5	-1.6	-2.1	-2.2	-1.9	-2.3
Eye problems/disorders: Glaucoma	0.9	1.0	2.4	-1.0	-1.2	-1.3	-1.2	-0.5	-0.8	-0.9	-0.5	-1.4	-1.4	-1.4	-1.0	-0.4	-1.2	-1.1	-1.1	-0.9	-1.5	-0.4	-1.2	-1.1	-0.4	-0.9	-0.6
Fed-up feelings	0.8	1.4	3.0	1.3	0.7	1.3	1.2	1.4	1.2	1.3	1.4	1.2	0.1	1.2	1.2	0.9	1.7	1.3	1.4	1.4	1.1	1.2	1.3	1.1	1.0	0.6	1.1
Multivitamins +/- minerals	0.8	1.0	2.4	-1.1	-0.2	-1.1	-1.1	-1.2	-1.0	-1.3	-1.2	-0.7	-1.1	-0.9	-0.8	-1.5	-0.9	-0.8	-1.1	-1.1	-0.9	-0.8	-1.1	-0.5	-1.1	-0.8	-0.9
Breastfed as a baby	0.8	1.0	2.6	1.0	1.0	1.1	1.0	0.9	1.4	1.4	1.3	0.6	0.7	0.7	0.6	1.6	0.4	1.0	0.5	1.0	1.0	1.4	1.2	0.3	1.0	1.1	1.0
Forced vital capacity (FVC), Best measure	0.8	3.1	9.1	-1.2	0.9	-1.6	-1.8	-1.9	-2.4	-1.5	-2.8	-2.1	-3.0	-2.3	-1.7	-1.3	-0.7	-1.3	-1.1	-1.8	-1.6	-1.2	-2.0	-0.3	-0.9	-2.9	-1.1
Number of children fathered	0.8	0.9	2.4	-0.8	0.1	-0.9	-0.8	-1.5	-1.1	-0.7	-1.4	-0.9	-0.6	-0.8	-1.2	-1.3	-1.2	-1.1	-1.0	-1.1	-0.6	-1.1	-1.0	-0.5	-0.8	-1.2	-0.9
Average weekly red wine intake	0.8	1.2	3.3	-1.4	-0.8	-0.9	-1.1	-1.4	-0.8	0.2	-0.8	-1.4	-1.2	-1.8	-0.8	-0.4	-1.7	-1.0	-1.6	-1.3	-0.7	-0.6	-0.8	-1.1	-0.9	-1.4	-0.9
Miserableness	0.8	1.3	6.3	-0.8	-1.3	-0.8	-1.0	-1.0	-0.5	0.1	-1.4	-1.8	-2.5	-1.9	-1.3	-1.4	-0.9	-1.1	-1.1	-1.0	-0.9	-1.2	-0.9	-0.6	-0.1	-0.9	-0.1
Alcohol drinker status: Never	0.8	0.9	2.1	1.4	0.5	0.8	1.0	0.9	0.4	0.0	0.3	1.1	0.7	1.1	0.7	1.5	1.3	1.1	1.2	1.0	0.5	-0.0	0.7	1.3	1.3	1.3	1.4
Diastolic blood pressure, automated reading	0.8	2.4	11.4	0.2	-0.9	1.9	0.9	1.2	1.5	3.4	2.2	1.1	1.2	1.0	2.0	2.1	-0.0	1.6	0.2	0.8	1.6	3.3	2.1	-0.2	-0.7	0.3	-0.5
Commuting to job workplace: Cycle	0.8	1.0	2.9	-1.0	-0.3	-1.0	-1.2	-1.0	-1.0	-0.8	-1.0	-1.2	-0.4	-1.3	-0.7	-0.5	-1.1	-0.8	-1.1	-1.3	-1.0	-0.6	-0.9	-0.9	-1.1	-1.7	-1.1
Age at First Birth	0.7	1.0	2.4	1.2	-0.6	1.0	1.0	1.3	0.9	0.8	0.9	0.8	1.2	0.8	0.5	0.5	1.5	0.9	1.5	1.2	0.7	-0.1	0.8	1.0	1.0	1.3	1.1
Neuroticism (2016)	0.7	1.0	3.3	-0.8	-1.0	-1.1	-1.0	-1.3	-0.8	-1.2	-1.2	-0.9	-0.8	-0.8	-1.0	-1.6	-0.2	-1.2	-0.6	-0.9	-1.1	-1.8	-1.1	-0.8	-0.8	-1.1	-0.7
Blood Platelet Count	0.7	8.1	11.1	-3.2	-3.3	-3.2	-3.2	-2.9	-3.0	-2.3	-2.6	-3.2	-1.0	-3.3	-3.0	-2.3	-3.2	-3.1	-3.3	-3.1	-3.0	-2.6	-3.1	-2.9	-2.4	-2.7	-2.5
Hand grip strength (left)	0.7	1.8	7.3	1.2	0.8	1.7	1.3	1.3	1.7	2.7	1.2	0.7	0.5	0.3	1.5	1.0	0.6	1.6	0.8	1.3	1.6	1.9	1.7	1.2	1.7	0.4	1.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.1	0.7	0.4	0.7	0.9	1.3	1.1	0.4	1.2	1.1	1.4	0.9	0.9	0.8	0.2	0.7	0.5	0.9	0.9	1.4	0.8	0.6	0.4	1.3	0.7
Body mass index (BMI)	0.7	3.0	6.9	-2.0	-2.2	-1.7	-1.8	-1.8	-1.6	-0.6	-1.4	-1.7	-0.6	-1.8	-1.2	-1.8	-2.6	-1.7	-2.5	-1.9	-1.5	-1.1	-1.4	-2.0	-1.8	-2.1	-2.0
Had menopause	0.7	0.9	2.4	-1.1	-1.5	-1.2	-1.1	-1.4	-0.3	-1.0	0.0	-0.5	-0.3	-0.5	-0.6	-1.1	-1.1	-0.8	-0.9	-0.8	-1.5	-1.1	-1.0	-1.0	-0.9	-1.1	-1.0
Had other major operations	0.7	0.9	2.3	-0.8	0.1	-1.0	-1.0	-0.7	-0.9	-0.3	-1.1	-1.2	-1.5	-1.1	-1.2	-1.0	-1.0	-1.0	-0.8	-0.9	-1.2	-1.2	-1.0	-0.3	-0.4	-1.3	-0.4
Fluid intelligence score	0.7	1.5	3.5	1.0	1.9	1.3	1.3	0.8	1.4	0.9	1.0	1.7	1.8	1.6	1.3	0.6	0.8	1.1	0.9	1.0	1.5	1.8	1.4	0.9	0.6	1.3	0.7
Neuroticism score	0.7	1.4	3.2	1.6	1.1	1.3	1.5	0.9	1.8	0.8	0.3	0.8	-0.4	1.0	0.7	-0.0	1.7	1.3	1.5	1.3	1.4	0.2	1.2	1.5	1.5	1.3	1.7
Weight	0.7	3.4	9.9	-1.2	-1.5	-2.0	-1.7	-1.6	-2.1	-1.7	-2.5	-1.9	-1.5	-2.0	-1.8	-3.1	-1.6	-1.9	-1.6	-1.6	-1.9	-2.7	-2.1	-0.7	-0.7	-2.4	-1.1
Hip circumference	0.7	2.8	8.2	-1.4	-1.8	-1.7	-1.6	-1.6	-1.7	-1.4	-1.8	-1.8	-1.0	-2.0	-1.3	-2.9	-1.9	-1.5	-2.0	-1.6	-1.5	-2.3	-1.7	-1.0	-1.0	-2.1	-1.3
Back pain experienced in last month	0.7	1.1	3.1	-0.5	-1.8	-1.2	-0.6	-0.9	-0.7	-1.5	-1.1	-1.3	-1.7	-1.2	-1.5	-1.4	-0.7	-1.2	-0.6	-0.5	-0.9	-1.5	-1.2	-0.2	0.2	-0.3	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	3.3	-1.3	0.0	-1.3	-1.4	-1.4	-1.5	-0.9	-1.2	-1.7	-1.8	-1.7	-1.6	-0.2	-1.4	-1.2	-1.3	-1.3	-1.3	0.5	-1.4	-1.1	-0.8	-1.5	-1.0
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.1	-0.7	-0.8	-1.0	-0.9	-0.6	-1.1	-1.1	-0.8	-0.8	-1.5	-0.8	-1.2	-0.4	-0.2	-1.1	-0.5	-0.7	-1.0	-0.5	-1.2	-0.8	-0.6	-1.1	-0.7
Alzheimer’s Disease (in father)	0.6	0.6	2.3	-0.6	0.1	-0.7	-0.6	-1.0	-0.3	-0.2	-1.1	-0.8	-1.5	-1.0	-1.0	-1.3	-1.0	-0.8	-0.8	-0.7	-0.7	-0.8	-0.7	-0.5	0.2	0.0	-0.1
Ulcerative Colitis	0.6	0.8	2.1	0.9	-0.4	0.9	1.0	1.4	1.4	0.7	0.6	0.9	1.1	0.9	0.7	1.1	0.9	0.7	1.1	1.0	0.8	0.6	0.7	0.9	0.9	1.0	0.8
Blood Red Count	0.6	5.5	12.3	-1.9	-3.0	-2.7	-2.3	-1.8	-2.1	-2.4	-2.9	-3.0	-3.5	-3.0	-2.6	-2.5	-2.5	-2.4	-2.1	-2.4	-2.7	-2.0	-2.6	-1.6	-0.6	-1.8	-1.0
Height	0.6	10.6	52.0	1.5	1.0	-2.4	-0.8	-1.8	-3.0	-5.8	-5.1	-1.9	-4.2	-1.8	-3.6	-6.1	2.1	-2.2	1.6	-0.4	-2.5	-7.2	-3.8	3.1	2.5	-2.0	2.2
Angina	0.6	0.8	2.8	-0.9	-1.7	-1.1	-0.9	-1.0	-0.9	-0.7	-0.6	-0.7	-0.5	-0.7	-0.8	-1.1	-1.3	-1.0	-1.1	-0.9	-1.1	-1.2	-1.0	-0.4	-0.8	-0.4	-0.7
Past tobacco smoking	0.6	1.0	2.5	0.9	0.2	1.1	1.0	1.1	0.6	0.8	1.2	1.0	1.5	0.8	1.4	0.5	0.9	1.4	0.9	1.0	1.0	1.6	1.2	0.8	0.8	1.5	0.8
Qualifications: None of the above	0.6	1.4	3.4	-1.1	-1.3	-1.3	-1.2	-1.2	-1.1	-1.6	-0.8	-0.3	-0.3	-0.1	-0.7	-1.3	-0.9	-1.4	-1.1	-1.3	-1.0	-1.2	-1.3	-1.5	-1.8	-1.5	-1.8
Heart attack	0.6	0.8	2.8	-0.9	-1.2	-1.0	-0.8	-0.8	-0.8	-1.0	-0.1	-0.2	-0.7	-0.2	-0.3	-1.6	-0.9	-0.6	-1.0	-0.9	-0.6	-0.9	-0.8	-0.6	-1.7	-1.0	-1.3
Pulse wave Arterial Stiffness index	0.6	0.7	1.9	-0.9	-0.2	-0.8	-0.8	-0.9	-0.5	-0.4	-0.7	-0.8	-1.2	-0.7	-0.8	-1.4	-0.7	-0.7	-0.9	-0.9	-0.6	-1.3	-0.7	-0.8	-1.0	-1.0	-0.9
Shortness of breath walking on level ground	0.6	0.8	2.7	-1.2	-0.1	-0.7	-1.0	-0.6	-0.3	-0.0	0.6	-0.2	0.8	-0.1	-0.5	-1.1	-0.9	-0.9	-1.1	-0.7	-0.8	-0.2	-0.5	-1.3	-1.5	-1.4	-1.7
Overall health rating	0.6	1.4	4.1	1.1	1.7	1.3	1.1	1.2	1.0	1.0	1.3	2.0	0.1	2.0	1.3	-0.4	1.6	1.4	1.3	1.2	1.0	0.6	1.3	1.1	0.1	0.2	0.4
Age at last live birth	0.6	0.8	2.5	-1.2	-0.7	-0.9	-0.9	-0.8	-0.6	-0.4	-0.9	-0.8	0.2	-0.9	-1.0	-0.5	-1.6	-0.8	-1.2	-1.1	-0.9	-1.0	-0.7	-1.5	-0.8	-0.5	-0.9
Leg fat-free mass (right)	0.6	3.0	10.9	-0.5	-0.3	-1.8	-1.2	-1.5	-1.5	-1.4	-3.3	-2.2	-2.1	-2.3	-2.3	-2.4	-1.4	-1.7	-1.1	-1.3	-1.8	-2.9	-2.0	-0.0	0.6	-2.1	0.1
Qualifications: nursing, teaching	0.6	0.9	2.8	1.0	0.3	1.2	1.0	0.7	0.8	1.5	0.6	1.0	1.7	0.8	0.6	0.8	1.1	1.0	1.0	1.0	0.9	0.3	1.2	1.0	0.6	0.8	0.9
Leg predicted mass (right)	0.6	2.9	10.7	-0.5	-0.3	-1.7	-1.2	-1.4	-1.5	-1.4	-3.3	-2.1	-2.1	-2.2	-2.3	-2.4	-1.4	-1.6	-1.0	-1.3	-1.7	-2.9	-2.0	0.0	0.6	-2.1	0.2
Wears glasses or contact lenses	0.6	0.7	2.0	-0.6	-0.4	-0.7	-0.9	-0.1	-0.4	-1.1	-0.7	-1.1	-1.4	-1.3	-0.7	-1.1	-0.5	-0.6	-0.8	-1.0	-0.7	-1.0	-0.9	-0.4	-0.7	-1.3	-0.5
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.5	0.8	0.3	0.6	0.7	0.7	-0.3	-0.4	1.0	1.6	1.2	1.4	1.1	1.0	1.4	0.8	1.0	0.7	0.7	0.8	0.5	0.8	-0.0	0.1	-0.1
Medication: Atorvastatin	0.6	0.7	2.4	-0.5	-1.5	-1.0	-0.8	-0.6	-1.0	-1.1	-0.6	-0.8	-1.5	-0.4	-1.0	-0.7	-0.7	-0.8	-0.7	-0.8	-1.0	-0.5	-0.9	-0.5	-0.9	-0.5	-0.7
Average weekly beer plus cider intake	0.6	0.8	3.3	-0.8	-1.8	-1.0	-0.7	-1.2	-1.4	-1.5	-0.6	-0.2	-0.1	-0.3	-0.8	0.1	-0.9	-0.9	-0.9	-0.8	-0.7	-0.9	-0.9	-0.7	-0.9	-0.7	-0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.8	3.0	-0.9	-1.2	-0.9	-0.8	-0.8	-0.8	-0.9	-0.0	-0.1	-0.4	-0.0	-0.2	-1.7	-0.9	-0.6	-1.0	-0.9	-0.6	-0.8	-0.7	-0.6	-1.7	-1.0	-1.4
Neuroticism (Nagel 2018)	0.5	1.2	2.5	1.5	0.5	1.2	1.3	0.8	1.3	1.1	0.2	0.9	-0.1	1.0	0.9	0.0	1.6	1.2	1.4	1.2	1.1	0.2	1.1	1.5	1.2	1.4	1.5
Lung FEV1/FVC ratio	0.5	2.3	8.2	-1.7	-1.9	-1.4	-1.6	-1.7	-2.2	-1.1	-0.4	0.1	1.1	0.6	-1.0	-1.1	-1.3	-1.6	-1.5	-1.3	-1.7	0.1	-1.1	-2.1	-2.8	-1.2	-2.9
Neuroticism	0.5	1.1	2.6	1.3	1.1	1.3	1.1	1.2	1.6	1.2	0.5	0.6	-0.1	0.7	0.8	0.1	1.6	1.2	1.2	1.0	1.3	0.4	1.2	1.3	1.0	0.9	1.2
Medication: Metformin	0.5	0.7	2.0	1.2	-0.6	0.5	0.9	1.4	0.4	0.3	0.3	1.0	1.1	1.2	0.3	1.4	0.7	0.6	0.7	0.8	0.5	0.4	0.6	0.3	0.7	1.3	0.9
Leg fat-free mass (left)	0.5	2.9	9.8	-0.5	-0.2	-1.7	-1.2	-1.4	-1.6	-1.6	-3.1	-1.9	-2.0	-2.1	-2.1	-2.5	-1.3	-1.6	-1.0	-1.3	-1.8	-3.0	-2.0	0.1	0.5	-2.1	0.1
Maternal smoking around birth	0.5	0.7	2.7	-1.0	-1.2	-0.9	-0.8	-1.1	-0.7	-0.8	0.1	-0.1	0.9	0.1	-0.5	-0.7	-0.9	-1.0	-1.0	-0.8	-0.6	-0.3	-0.8	-1.1	-1.6	-0.8	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.9	-1.1	-0.5	-1.4	-1.1	-1.1	-0.8	-1.2	-0.5	-1.3	-1.2	-1.2	-1.1	-0.7	-1.2	-1.4	-1.1	-1.0	-1.2	0.5	-1.3	-1.3	-0.4	-0.7	-0.7
Leg predicted mass (left)	0.5	2.8	9.6	-0.4	-0.2	-1.7	-1.2	-1.3	-1.6	-1.5	-3.1	-1.9	-1.9	-2.1	-2.1	-2.5	-1.2	-1.5	-0.9	-1.2	-1.7	-3.0	-2.0	0.1	0.5	-2.1	0.2
Alcohol usually taken with meals	0.5	0.7	6.0	-0.1	1.2	1.1	0.3	0.4	1.1	2.5	0.4	-0.3	-0.3	-0.7	0.7	0.8	-0.4	1.0	-0.3	0.0	0.9	1.5	1.2	0.0	0.5	-0.2	0.1
Hearing difficulty/problems with background noise	0.5	0.9	2.2	1.3	1.2	0.9	1.0	1.3	0.7	0.9	0.3	0.3	0.3	0.6	0.2	-0.1	1.1	0.5	1.2	1.1	0.8	-1.1	0.7	1.5	1.2	0.8	1.4
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.4	-0.6	-0.5	-0.6	-0.7	-0.6	0.1	-0.1	-0.9	-1.2	-1.6	-1.2	-0.8	-1.2	-0.6	-0.4	-0.7	-0.6	-0.9	-1.2	-0.6	-0.4	0.1	-0.7	-0.1
Father’s age at death	0.5	0.7	2.0	-0.5	-0.1	-0.9	-0.6	-0.9	0.3	-1.3	-1.2	-1.0	-1.4	-1.2	-0.8	-0.7	-0.9	-0.8	-0.8	-0.8	-0.7	-1.1	-0.9	-0.9	0.4	-0.3	0.2
Forced expiratory volume in 1-second (FEV1)	0.5	1.5	4.7	-1.1	0.9	-1.1	-1.4	-1.3	-2.0	-1.0	-1.6	-1.0	-1.5	-1.1	-0.8	-1.4	-0.5	-0.9	-0.9	-1.3	-1.2	-0.5	-1.3	-0.5	-1.4	-2.2	-1.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.1	1.0	1.1	1.1	0.9	1.4	0.7	0.7	0.8	0.8	-0.3	0.9	0.6	0.4	1.1	0.8	1.1	1.0	0.8	0.5	0.9	0.5	0.7	0.3	0.9
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	4.9	0.9	2.2	0.9	1.0	0.5	0.3	0.2	1.0	1.6	1.0	1.6	1.4	0.6	0.8	0.7	0.7	0.8	1.4	1.3	0.8	0.6	-0.2	1.0	0.1
Number of full brothers	0.5	0.6	1.6	1.0	1.1	0.7	0.8	0.5	0.4	0.3	0.5	0.9	0.6	0.9	0.3	0.3	1.0	0.6	1.0	0.9	0.6	0.0	0.7	1.2	0.8	0.8	1.1
Pulse wave peak to peak time	0.5	0.5	1.2	0.9	0.2	0.6	0.8	0.8	0.4	0.1	0.2	0.7	0.9	0.6	0.6	1.1	0.7	0.6	0.9	0.8	0.5	1.1	0.5	1.0	1.0	0.9	1.0
Angina (self-reported)	0.5	0.6	2.1	-0.7	-1.5	-1.0	-0.7	-0.9	-0.7	-0.7	-0.5	-0.6	-0.6	-0.6	-0.6	-0.9	-1.2	-0.8	-1.0	-0.7	-0.8	-1.1	-0.8	-0.2	-0.5	-0.3	-0.5
Medication: Ibuprofen	0.5	0.5	4.6	-0.5	0.3	-0.6	-0.6	-0.7	-0.4	-0.5	-1.2	-0.7	-2.1	-0.7	-1.0	-1.0	-0.5	-0.5	-0.4	-0.5	-1.0	0.1	-0.7	-0.3	0.2	-0.4	0.0
Pulse rate, automated reading	0.5	1.8	5.6	-1.8	-1.4	-1.3	-1.5	-1.3	-1.5	-0.8	0.2	-0.1	0.9	-0.2	-0.2	-1.4	-1.5	-1.1	-1.6	-1.2	-1.4	-1.0	-1.0	-1.9	-2.4	-1.7	-2.1
Comparative height size at age 10	0.5	2.7	8.6	2.5	2.6	1.5	1.6	1.6	1.0	0.1	-0.7	1.2	0.8	1.1	1.3	-0.8	2.8	1.7	2.4	1.5	1.4	-1.8	0.8	2.9	1.8	-0.2	1.9
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.7	2.3	0.9	0.5	0.3	0.9	0.8	0.5	-0.2	1.1	0.8	1.4	0.8	0.4	0.5	0.8	0.3	1.1	1.1	0.5	-0.1	0.3	0.8	1.1	1.5	1.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.0	-1.1	-1.0	-0.6	-0.8	-0.4	-0.4	-0.1	0.1	-0.7	0.1	-0.7	-0.1	-0.4	-1.4	-0.6	-1.3	-0.8	-0.4	-0.1	-0.4	-1.3	-1.1	-0.7	-1.2
Supplements: Vitamin C	0.5	0.6	1.9	-0.9	0.3	-0.6	-0.7	-0.8	-0.2	0.2	-0.5	-1.1	-1.4	-1.2	-0.5	-0.9	-1.3	-0.5	-1.2	-0.9	-0.1	0.7	-0.3	-0.9	-0.6	-1.0	-0.7
Diabetes diagnosed by doctor	0.5	0.8	2.8	1.2	0.1	0.9	1.0	1.4	0.5	0.3	0.5	1.2	0.6	1.4	0.9	1.7	1.1	0.9	1.0	0.8	1.0	0.8	0.9	0.4	0.2	0.6	0.5
Medication: Paracetamol	0.5	0.7	1.7	-0.9	-1.1	-0.9	-0.9	-1.0	-1.3	-0.9	-0.9	-0.4	0.1	-0.1	-0.8	-1.0	-0.4	-1.0	-0.7	-0.8	-0.9	-0.7	-0.9	-0.6	-1.3	-1.0	-1.1
Fractured/broken bones in last 5 years	0.5	0.6	3.1	-0.6	-1.8	-0.5	-0.8	-0.2	0.1	0.4	0.2	-0.7	0.6	-0.6	-1.0	-0.6	-0.8	-0.6	-0.8	-0.3	-1.2	-1.6	-0.4	-1.1	0.1	-0.9	-0.3
Age started oral contraceptive pill	0.5	0.7	1.1	-0.9	-0.8	-0.8	-1.0	-0.8	-0.9	-0.9	-0.2	-0.8	-0.9	-0.8	-0.9	-0.5	-0.9	-0.7	-0.9	-0.9	-1.1	-0.7	-0.8	-0.7	-0.9	-1.0	-1.0
Supplements: Calcium	0.5	0.6	2.3	0.7	0.3	0.9	0.7	0.7	1.5	1.0	0.3	0.2	-0.4	-0.4	0.4	-0.0	0.5	0.9	0.7	0.6	0.7	0.4	0.8	0.5	1.3	0.8	1.4
Heart disease (siblings)	0.5	0.6	1.3	-0.7	0.7	-0.9	-0.7	-0.9	-1.0	-0.8	-0.7	-0.5	-0.2	-0.3	-0.7	-1.1	-0.9	-0.7	-0.8	-0.9	-0.7	-1.1	-0.8	-0.5	-1.0	-0.8	-0.8
Depressed Affect (Nagel 2018)	0.4	0.9	2.7	0.9	0.6	1.3	0.9	0.8	1.3	1.6	1.0	0.9	-0.3	0.8	1.2	0.4	1.0	1.1	0.7	1.0	1.2	1.2	1.3	0.7	0.6	0.7	0.8
Alzheimer’s Disease (in mother)	0.4	0.4	3.3	-0.2	0.1	0.6	0.2	0.7	0.6	1.2	1.8	0.7	0.5	0.6	1.1	0.1	-0.2	0.7	-0.2	0.7	0.4	0.3	0.9	-0.5	-0.1	0.6	-0.2
Ulcerative Colitis (UC)	0.4	0.7	1.7	1.0	-0.2	0.8	0.9	1.1	1.2	1.3	0.7	0.5	0.6	0.8	0.3	0.8	1.1	0.5	1.2	1.0	0.7	0.1	0.6	1.0	0.6	0.8	0.7
Blood Eosinophil Count	0.4	2.9	7.1	-1.5	-2.0	-1.9	-1.7	-2.0	-2.1	-2.7	-1.8	-1.3	-1.3	-1.4	-1.1	-1.4	-1.3	-1.9	-1.5	-1.8	-1.6	-2.6	-2.1	-1.5	-1.4	-1.4	-1.5
Blood White Count	0.4	3.3	10.8	-1.2	-3.1	-2.0	-1.6	-1.8	-1.7	-2.1	-2.0	-2.1	-1.3	-2.4	-2.6	-0.8	-1.4	-1.9	-1.4	-1.5	-2.0	-3.3	-2.2	-1.0	-0.1	-0.5	-0.3
Smoking Status	0.4	1.0	2.9	-0.8	-0.2	-1.1	-1.1	-1.0	-1.3	-0.7	-1.4	-1.1	-0.8	-0.8	-1.6	-0.6	-0.4	-1.3	-0.6	-0.9	-1.1	-1.3	-1.3	-0.5	-0.8	-1.7	-0.9
Average weekly spirits intake	0.4	0.5	2.3	-1.0	0.8	-0.6	-0.9	-0.7	-0.7	-0.4	-0.5	-0.2	-0.7	-0.4	-0.2	-0.4	-0.3	-0.6	-0.6	-0.7	-0.5	-0.5	-0.6	-0.7	-1.5	-1.1	-1.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.2	-0.8	0.2	-0.7	-0.7	-0.7	-1.0	-0.3	-0.4	-0.7	0.2	-0.4	-0.3	0.3	-1.0	-0.5	-1.0	-0.8	-0.5	0.1	-0.4	-1.1	-0.9	-1.1	-0.9
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.0	0.7	1.0	0.9	0.7	1.0	0.7	0.9	0.9	0.2	0.6	0.5	0.1	0.6	0.8	0.5	0.7	0.8	0.8	0.6	0.7	0.6	0.6	0.5	0.6
Forced vital capacity (FVC)	0.4	1.6	6.2	-0.7	1.3	-0.9	-1.3	-1.1	-1.8	-0.6	-2.0	-1.3	-2.5	-1.5	-0.9	-1.2	-0.1	-0.6	-0.5	-1.1	-1.1	-1.2	-1.4	0.3	-0.7	-2.5	-0.9
Diabetes (self-reported)	0.4	0.6	2.8	1.0	-0.2	0.6	0.9	1.0	0.2	0.1	0.2	1.1	0.9	1.3	0.8	1.7	0.7	0.6	0.7	0.6	0.9	0.8	0.7	0.4	0.1	0.5	0.4
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.6	0.3	-0.1	0.9	0.6	1.6	1.3	1.4	0.9	0.3	0.5	0.2	0.9	0.0	0.5	0.7	0.6	0.9	0.8	0.6	0.9	0.1	0.2	0.3	0.6
Exposure to tobacco smoke at home	0.4	0.5	1.9	-0.2	-0.5	-0.9	-0.6	-0.6	-1.4	-1.3	-0.5	-0.3	-0.7	-0.0	-1.0	-0.2	0.1	-1.1	-0.0	-0.2	-1.1	-0.3	-1.1	-0.1	-0.5	-0.4	-0.4
Age at first live birth	0.4	0.7	1.9	-0.9	-0.7	-0.8	-0.7	-1.0	-0.6	-0.7	-1.0	-0.9	0.7	-0.9	-0.8	0.0	-1.4	-0.6	-1.1	-1.1	-0.6	-1.2	-0.6	-1.2	-0.7	-0.3	-0.7
Neck or shoulder pain in last month	0.4	0.6	2.2	-0.5	-0.8	-0.8	-0.6	-0.9	-1.3	-0.7	-0.5	-0.7	-1.3	-0.5	-1.2	-0.8	-0.2	-1.0	-0.3	-0.2	-1.0	-1.5	-1.0	-0.1	-0.2	-0.5	-0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.9	-1.0	-0.7	-0.2	-0.8	-0.5	-1.0	-0.0	-0.4	-0.5	-0.2	-0.7	0.1	-1.0	-0.5	-0.1	-0.8	-0.6	-0.2	-0.1	-0.2	-0.2	-1.4	-0.8	-1.3
Smoking status: Previous	0.4	0.7	1.3	-0.9	0.1	-0.8	-0.8	-1.1	-0.6	-0.3	-0.8	-0.7	-0.9	-0.4	-1.0	-0.3	-0.8	-1.1	-0.8	-0.8	-0.5	-1.1	-0.8	-0.9	-1.1	-1.1	-1.1
Mood swings	0.4	0.8	1.5	1.0	1.0	1.0	1.0	0.6	1.1	0.7	0.7	0.9	-0.1	0.9	1.2	0.4	0.9	1.1	0.8	0.8	1.2	0.8	1.0	1.0	0.6	0.9	0.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.5	-0.7	-1.5	-0.8	-0.6	-0.4	-0.3	-0.9	-0.1	-0.7	-1.6	-1.0	-1.0	0.6	-1.1	-0.8	-0.8	-0.5	-0.7	-0.3	-0.7	-1.1	0.5	-0.2	0.2
Financial situation satisfaction	0.4	0.5	1.5	0.7	0.6	0.8	0.4	1.0	0.7	1.2	-0.0	-0.5	-1.0	-0.6	0.3	0.9	0.7	0.6	0.5	0.5	0.4	0.7	0.5	0.8	1.1	-0.1	1.1
Ever smoked	0.4	0.7	2.8	-0.6	-0.4	-0.7	-0.7	-0.9	-0.3	-0.2	-1.0	-1.2	-1.7	-1.2	-1.1	0.2	-0.6	-0.9	-0.7	-0.7	-0.6	-1.4	-0.8	-0.3	-0.0	-1.1	-0.0
Ever depressed for a whole week	0.4	0.5	2.0	0.6	-0.3	0.6	0.6	0.8	1.2	0.6	0.4	-0.0	-0.4	-0.3	0.2	0.6	0.7	0.6	0.8	0.8	0.4	0.0	0.5	0.7	1.4	1.0	1.3
Unable to work because of sickness or disability	0.4	0.5	2.1	0.0	-0.1	-0.7	-0.3	-0.4	-1.4	-1.1	-0.8	0.1	-1.2	0.4	-0.6	-0.9	0.5	-0.7	0.5	-0.1	-0.9	-1.2	-0.9	0.7	-0.1	-0.1	-0.1
Impedance of whole body	0.4	2.3	5.7	-1.6	-2.4	-1.6	-1.6	-1.6	-2.4	-2.4	-0.4	-0.4	0.4	-0.2	-1.0	-2.0	-0.6	-1.5	-1.2	-1.3	-1.8	-1.8	-1.7	-1.2	-2.1	-0.7	-1.8
Schizophrenia vs Biploar Disorder	0.3	0.3	2.3	-0.6	-1.5	-0.2	-0.5	-0.1	-0.6	-0.0	0.5	-0.0	1.2	0.1	-0.5	-0.5	-0.5	-0.7	-0.5	-0.1	-0.5	-0.0	-0.3	-0.9	-0.7	-0.3	-0.7
Worry (Nagel 2018)	0.3	0.6	2.5	1.1	0.4	0.8	0.9	0.6	0.8	0.5	0.0	0.5	0.5	0.6	0.4	-0.5	1.6	0.7	1.2	0.9	0.7	-0.5	0.6	1.2	0.8	1.1	1.0
Body Mass Index (BMI) (2010)	0.3	0.4	1.2	-0.6	0.7	-0.5	-0.7	-0.5	-0.7	-0.6	-0.4	-0.0	-0.2	-0.1	-0.0	-0.9	-0.3	-0.5	-0.5	-0.7	-0.6	0.0	-0.6	-1.0	-1.1	-1.1	-1.0
HbA1C	0.3	0.4	3.0	0.7	0.1	-0.0	0.4	0.6	0.4	-0.6	-0.1	0.2	-0.8	-0.1	-0.2	1.7	0.2	0.2	0.5	0.5	0.1	0.0	-0.0	0.8	0.9	1.2	1.0
BMI	0.3	1.9	4.9	-1.4	-1.9	-1.3	-1.3	-1.9	-1.1	-0.1	-1.4	-1.7	-0.3	-1.7	-1.0	-1.0	-2.2	-1.3	-2.0	-1.6	-1.1	-0.7	-1.1	-1.6	-1.1	-1.5	-1.3
Waist Hip Ratio (WHR)	0.3	1.5	4.2	-1.4	-1.1	-1.4	-1.4	-0.8	-1.3	-0.8	-0.6	-0.5	0.4	-0.2	-0.8	-0.2	-1.0	-1.4	-1.2	-1.3	-1.5	-0.8	-1.2	-1.9	-2.0	-1.9	-1.7
Allergy or Eczema	0.3	0.7	2.6	-1.1	-1.1	-0.7	-0.8	-0.7	-0.6	-0.5	-1.0	-0.9	-1.6	-1.0	-0.6	-1.4	-0.9	-0.6	-0.9	-0.8	-0.6	-0.2	-0.6	-1.0	-0.7	-0.4	-0.7
Hypothyroidism (self reported)	0.3	0.7	4.1	0.6	2.0	0.7	0.7	0.4	-0.1	0.3	0.8	1.4	0.9	1.4	1.1	-0.0	0.6	0.5	0.6	0.6	1.0	1.0	0.6	0.5	-0.4	0.7	-0.1
Lung FVC	0.3	1.8	7.2	-1.5	0.7	-1.0	-1.7	-1.5	-1.3	-0.4	-1.0	-1.2	-2.2	-1.4	-0.6	-0.1	-0.9	-0.6	-1.4	-1.6	-1.2	0.0	-1.0	-1.2	-1.8	-2.7	-2.0
Number of treatments/medications taken	0.3	0.5	2.5	-0.9	-0.7	-0.3	-0.7	-0.5	-0.4	0.5	-0.3	-0.4	-1.6	-0.2	-0.6	-0.9	-0.4	-0.6	-0.5	-0.7	-0.6	0.1	-0.3	-0.9	-1.3	-1.0	-1.1
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.7	0.7	1.0	0.7	0.4	0.3	0.3	1.3	0.3	0.4	-1.1	0.5	0.2	-0.4	1.1	0.7	0.8	0.7	0.1	-0.4	0.5	0.9	0.4	0.2	0.5
Ever had hysterectomy (womb removed)	0.3	0.3	1.4	0.3	0.9	0.6	0.4	1.2	0.1	0.8	0.8	-0.1	-0.3	-0.1	-0.0	0.7	0.6	0.4	0.5	0.8	0.3	0.5	0.4	0.6	0.7	0.2	0.7
Severe depression (siblings)	0.3	0.3	1.4	0.5	0.1	0.4	0.6	1.2	0.3	0.2	0.9	0.3	-0.6	0.4	0.2	0.6	1.0	0.4	0.8	0.7	0.7	-0.5	0.4	0.7	0.6	0.4	0.6
Impedance of leg (right)	0.3	1.4	4.7	0.4	-0.2	0.9	0.7	1.1	0.1	-0.2	2.2	2.0	2.0	2.1	1.6	-0.2	1.8	0.8	1.1	1.2	0.8	1.0	0.8	0.7	-0.7	1.4	-0.2
Taking other prescription medications	0.3	0.4	1.9	-0.7	-1.0	-0.5	-0.7	-0.2	-0.0	0.1	0.2	-0.1	-0.2	0.1	-0.3	-1.2	-0.4	-0.5	-0.4	-0.4	-0.8	-1.4	-0.4	-0.7	-1.2	-0.8	-1.0
Serious illness, injury or assault to yourself	0.3	0.4	2.0	-0.2	-0.7	-0.5	-0.4	-0.5	-0.3	-0.1	-0.8	-0.3	-1.4	-0.7	-0.8	-0.3	-0.6	-0.3	-0.5	-0.4	-0.8	-1.2	-0.5	0.1	0.2	-0.7	0.2
Supplements: Glucosamine	0.3	0.4	2.6	-0.5	0.4	-0.6	-0.6	-0.3	-0.6	-0.9	-0.7	-0.1	-0.4	0.1	-0.5	-1.6	-0.3	-0.8	-0.4	-0.4	-0.8	0.2	-0.7	-0.2	-0.8	-0.5	-0.7
Sitting height	0.3	2.3	9.4	2.2	2.5	0.9	1.4	1.6	1.0	0.2	-0.9	0.3	-0.9	0.2	0.2	-1.8	1.8	1.1	2.0	1.5	0.7	-0.6	0.4	3.1	2.8	0.7	2.5
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	3.5	0.6	1.0	0.3	0.3	0.4	0.4	0.2	-0.1	0.6	-1.9	0.5	0.3	-0.5	0.9	0.7	0.8	0.5	-0.1	-0.0	0.2	1.0	0.7	0.3	0.7
Medication: Simvastatin	0.3	0.5	1.9	0.5	0.5	0.8	0.7	0.3	0.2	0.6	0.5	1.3	0.7	1.3	0.7	0.2	0.6	0.5	0.6	0.4	1.0	1.4	0.9	-0.1	-0.3	0.4	-0.1
Trunk fat-free mass	0.3	1.8	6.0	2.0	2.4	1.1	1.4	1.6	1.3	0.8	-0.6	0.5	-0.4	0.3	0.6	-0.5	1.6	1.1	1.8	1.5	1.0	-0.2	0.6	2.5	2.2	0.1	2.1
Alcohol intake versus 10 years previously	0.3	0.5	2.5	0.7	-0.7	0.1	0.4	-0.2	-0.1	-0.9	-0.2	1.3	1.6	1.6	0.1	0.7	1.0	-0.0	0.8	0.4	-0.1	-0.3	-0.1	0.4	-0.1	0.9	0.0
Mouth/teeth dental problems: Dentures	0.3	0.4	1.8	-0.6	-0.4	-0.9	-0.6	-0.2	-0.8	-1.4	-0.3	-0.0	-0.3	-0.1	-0.6	-1.1	-0.3	-0.9	-0.4	-0.6	-0.8	-0.5	-0.9	-0.6	-0.6	-0.8	-0.7
Trunk predicted mass	0.3	2.0	6.6	2.1	2.4	1.1	1.4	1.7	1.4	0.8	-0.5	0.6	-0.3	0.3	0.7	-0.5	1.7	1.2	1.9	1.6	1.1	-0.2	0.7	2.6	2.3	0.1	2.2
Standing height	0.3	2.8	13.2	1.6	1.2	-0.7	0.1	0.3	-1.1	-2.4	-2.4	-0.4	-1.5	-0.5	-1.2	-3.0	1.9	-0.4	1.7	0.6	-1.1	-3.6	-1.6	2.8	2.0	-0.9	1.9
Length of working week for main job	0.3	0.3	2.7	-0.1	0.1	0.4	0.0	0.2	0.4	1.2	0.4	0.1	0.4	-0.1	0.6	1.2	-0.6	0.4	-0.3	0.1	0.2	1.6	0.6	-0.1	-0.0	0.0	-0.0
Birth weight of first child	0.3	0.6	3.7	0.4	0.4	-0.3	-0.1	0.1	-0.7	-1.2	-0.9	-0.2	-1.9	-0.2	-1.2	-0.8	1.1	-0.6	0.8	0.0	-0.3	-0.4	-1.0	1.0	0.1	-1.1	0.2
Gout (self-reported)	0.3	0.4	1.2	-0.8	-0.6	-0.7	-0.7	-0.3	-0.2	-0.6	-0.4	-0.9	-0.7	-1.0	-0.5	-0.2	-1.0	-0.5	-1.1	-0.7	-0.4	0.1	-0.6	-0.7	-0.5	-0.2	-0.8
Worry too long after embarrassment	0.3	0.6	2.2	1.1	0.1	0.3	0.6	0.0	0.5	-0.1	-0.8	-0.1	-0.9	0.1	-0.4	-0.4	1.2	0.3	0.9	0.6	0.2	-1.5	0.1	1.3	1.1	0.9	1.2
Heart disease (mother)	0.3	0.3	0.9	0.5	-0.2	0.7	0.7	0.6	0.7	0.8	0.4	0.4	-0.7	0.3	0.4	0.8	0.3	0.3	0.3	0.6	0.7	0.9	0.6	0.2	0.6	0.9	0.8
Alcohol intake frequency.	0.3	0.6	4.6	0.8	-2.2	0.2	0.3	0.6	0.1	0.2	0.4	-0.5	-0.1	-0.2	-0.4	0.7	0.8	0.1	0.7	0.6	-0.4	-1.3	0.0	0.8	1.4	0.5	1.3
Suffer from ‘nerves’	0.3	0.5	2.3	-0.2	-0.7	-0.6	-0.5	-1.0	-0.7	-0.6	-1.1	-0.6	-0.6	-0.3	-1.0	-1.2	0.2	-0.6	-0.2	-0.5	-0.6	-1.5	-0.7	-0.3	-0.4	-0.3	-0.4
Medication: Aspirin	0.3	0.4	3.2	-0.7	-0.4	-0.3	-0.5	-0.5	-0.4	0.3	0.2	0.2	0.3	0.5	-0.1	-0.4	-0.8	-0.5	-0.7	-0.5	-0.2	0.1	-0.1	-1.0	-1.8	-0.6	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	3.7	0.3	-0.0	-0.6	-0.3	-0.7	-1.6	-1.4	-1.9	-0.5	-0.3	-0.3	-1.1	-1.1	0.6	-0.8	0.4	-0.3	-0.4	-1.2	-1.1	0.9	0.2	-0.6	0.2
Handedness (chirality/laterality): Left-handed	0.3	0.4	2.1	0.9	0.2	0.3	0.6	0.5	-0.1	-0.9	0.1	0.8	0.9	1.1	0.2	0.3	1.5	0.2	1.1	0.6	0.4	0.1	-0.1	0.6	-0.0	0.3	0.4
Commuting to job workplace: Walk	0.3	0.3	2.6	0.5	-0.4	-0.2	0.2	-0.3	-0.1	-0.5	-0.9	-0.2	-0.3	-0.1	-0.2	0.0	0.4	-0.3	0.5	0.1	-0.4	-1.6	-0.4	0.0	1.0	0.3	1.1
Medication: Aspirin	0.3	0.4	3.5	-0.7	-0.7	-0.3	-0.5	-0.6	-0.5	0.4	0.2	0.3	0.1	0.6	-0.1	-0.4	-0.7	-0.5	-0.7	-0.4	-0.2	0.1	-0.1	-1.1	-1.9	-0.5	-1.4
Illnesses of father: None of the above (group 1)	0.3	0.4	1.6	-0.5	-1.1	-0.5	-0.7	-0.8	-0.5	-0.1	-0.1	-0.9	0.1	-0.9	-1.2	-0.1	-0.5	-0.6	-0.6	-0.3	-0.9	-1.2	-0.6	-0.7	0.1	-0.6	-0.0
Guilty feelings	0.3	0.5	3.9	0.5	0.1	-0.3	0.4	-0.6	-0.4	-0.7	-2.0	-0.2	-0.9	0.1	-0.6	-0.4	-0.0	-0.3	0.3	-0.1	-0.1	-0.6	-0.2	0.7	0.9	1.2	1.1
Cholesterol lowering medication	0.3	0.4	1.6	0.9	-0.3	0.4	0.9	0.4	-0.0	-0.1	0.0	0.8	-0.1	1.3	-0.5	0.0	0.9	0.2	1.1	0.6	0.4	1.0	0.5	0.5	0.7	1.0	0.9
Bipolar Disorder (2018)	0.2	0.4	2.2	0.1	1.5	0.6	0.4	0.3	0.6	0.2	0.6	0.6	-1.3	0.6	0.4	0.0	0.6	0.7	0.4	0.2	0.8	0.7	0.6	-0.1	-0.3	-0.0	-0.4
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.0	0.8	0.8	0.7	0.7	0.9	0.9	0.2	0.2	0.6	1.4	0.5	0.5	1.1	1.0	0.6	0.9	0.8	0.6	0.8	0.6	0.7	0.8	0.6	0.8
Schizophrenia (2018)	0.2	0.4	1.5	-1.0	-0.4	-0.7	-0.6	-0.5	-0.6	-0.4	-0.6	-0.6	-0.8	-0.7	-0.8	-0.1	-1.2	-0.7	-0.9	-0.7	-0.6	-0.2	-0.4	-0.9	-0.3	-0.4	-0.5
Alzheimer’s Disease (including proxy)	0.2	0.3	1.2	-0.9	0.2	0.0	-0.4	-0.3	-0.1	0.9	1.0	0.3	-0.2	0.1	0.2	-1.1	-0.9	-0.2	-0.9	-0.2	-0.1	-0.3	0.1	-0.9	-0.9	-0.1	-1.0
Reaction Time	0.2	0.4	2.4	0.7	0.1	0.5	0.9	-0.0	0.5	-0.1	0.5	0.6	-0.5	0.5	0.7	0.5	0.0	0.8	0.3	0.6	0.9	0.6	0.7	0.4	0.9	1.5	0.9
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.9	-0.5	0.3	-0.6	-0.6	-0.8	-0.4	-0.9	-0.7	-0.2	0.5	-0.2	-0.5	-1.0	-0.8	-0.7	-0.7	-0.8	-0.5	-0.3	-0.6	-0.7	-0.7	-0.8	-0.7
Ovarian Cancer	0.2	0.2	0.7	-0.4	-0.8	-0.5	-0.5	-0.4	-0.7	-0.5	-0.5	0.0	-0.2	0.0	-0.4	0.5	-0.3	-0.8	-0.3	-0.5	-0.5	-0.1	-0.6	-0.4	-0.6	-0.8	-0.6
LDL Cholesterol	0.2	0.3	1.8	-0.9	0.2	-0.5	-0.6	-0.2	-0.8	-0.4	-0.3	0.4	-0.1	0.2	0.4	-0.6	-0.4	-0.4	-0.6	-0.6	-0.4	0.1	-0.5	-0.6	-1.4	-0.5	-1.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	3.7	1.0	-0.1	0.3	0.6	-0.4	-0.1	-0.1	-0.2	0.9	0.6	1.0	0.3	1.9	0.8	0.4	0.6	0.4	0.5	0.6	0.3	0.3	0.0	0.8	0.4
Tanning	0.2	2.3	3.8	-1.6	-1.7	-1.9	-1.6	-1.4	-1.4	-1.8	-1.6	-1.6	-0.8	-1.8	-1.4	-1.5	-1.8	-1.9	-1.7	-1.6	-1.7	-1.4	-1.9	-1.5	-0.6	-1.7	-0.9
Sensitivity / hurt feelings	0.2	0.4	1.4	-0.1	0.1	-0.7	-0.4	-1.2	-0.2	-0.9	-0.7	-0.7	-0.8	-0.4	-0.8	-0.7	-0.5	-0.6	-0.5	-0.6	-0.4	-0.9	-0.7	-0.3	-0.5	-0.4	-0.2
Vitamin and mineral supplements	0.2	0.3	1.7	0.4	-0.4	0.5	0.5	0.3	0.4	0.6	0.5	0.1	1.0	0.3	0.5	1.3	0.4	0.4	0.4	0.4	0.5	0.1	0.5	-0.1	0.5	0.3	0.3
Diabetes (mother)	0.2	0.2	1.6	-0.4	-0.2	-0.0	-0.3	-0.1	0.0	0.5	-0.1	-0.3	0.7	-0.4	0.2	1.3	-0.7	0.1	-0.6	-0.5	0.1	-0.3	0.2	-0.5	-0.6	-0.4	-0.7
Pack years adult smoking proportion	0.2	0.3	1.5	-0.4	-0.7	-0.5	-0.5	-0.5	-0.7	-0.7	-0.8	-0.2	-0.1	-0.2	-0.2	-0.6	0.1	-0.6	-0.3	-0.5	-0.4	-1.2	-0.7	-0.4	-0.9	-0.8	-0.6
Hand grip strength (right)	0.2	0.6	3.4	0.6	0.5	0.9	0.6	0.7	0.8	1.9	0.8	0.2	-0.0	-0.1	0.8	0.5	0.2	0.8	0.2	0.7	0.7	1.3	0.9	0.7	1.1	-0.2	0.7
Townsend deprivation index at recruitment	0.2	0.2	1.0	0.2	-0.0	-0.7	0.1	0.2	-0.6	-1.0	-0.3	0.7	0.5	1.0	-0.5	0.2	-0.2	-0.4	0.2	0.2	-0.8	-0.1	-0.5	0.3	0.3	0.7	0.3
Current tobacco smoking	0.2	0.4	1.8	0.8	0.6	0.2	0.4	0.6	0.2	-0.8	-0.1	0.5	0.4	0.6	0.2	0.1	1.3	0.4	1.1	0.6	0.2	-0.3	-0.0	1.2	0.5	-0.2	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	2.2	0.4	0.4	0.1	0.1	0.2	-0.0	0.3	0.2	0.2	-1.5	0.4	0.1	-1.0	1.0	0.3	0.6	0.4	-0.2	-0.2	0.0	0.7	0.3	0.0	0.3
Impedance of leg (left)	0.2	0.9	3.9	-0.0	-0.8	0.6	0.4	0.7	0.0	0.0	2.0	1.5	2.0	1.6	1.4	-0.2	1.2	0.6	0.6	0.8	0.6	0.9	0.7	0.3	-1.0	1.3	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.1	-0.6	0.0	-0.7	-0.5	-0.4	-0.5	-0.9	-0.1	-0.9	-0.4	-0.7	-0.5	-0.5	-0.8	-0.8	-0.7	-0.5	-0.4	0.6	-0.7	-1.1	-0.3	-0.2	-0.4
Pain all over the body in last month	0.2	0.2	1.8	0.3	1.3	0.1	0.4	-0.1	-0.3	-0.2	0.2	0.5	0.2	0.6	0.1	0.8	0.2	0.0	0.5	0.2	0.2	0.1	0.0	0.5	0.4	0.1	0.4
Pulse rate	0.2	0.3	1.0	-0.7	-0.4	-0.6	-0.6	-0.6	-0.4	0.0	-0.1	-0.4	0.7	-0.4	-0.1	-0.5	-1.0	-0.4	-0.8	-0.4	-0.8	-0.6	-0.3	-0.6	-0.5	-0.6	-0.4
Noisy workplace	0.2	0.3	1.3	0.0	-0.4	-0.2	-0.1	0.0	-0.5	-0.2	-0.6	-0.8	-1.0	-0.8	-0.8	0.8	0.0	-0.2	0.0	-0.1	-0.2	-1.2	-0.3	0.6	0.6	-0.4	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	2.5	0.1	0.2	-0.3	-0.1	-0.3	-0.1	-0.5	-0.9	-0.2	-1.6	-0.2	-0.5	-0.5	-0.1	-0.1	0.0	-0.2	-0.6	0.2	-0.3	0.3	0.6	0.0	0.4
Medication: Cholesterol lowering	0.2	0.3	1.0	0.4	0.4	0.5	0.3	0.8	-0.0	0.0	0.6	1.0	-0.7	1.0	0.8	-0.1	0.7	0.4	0.4	0.3	0.6	0.5	0.3	0.4	-0.7	-0.3	-0.5
Depression (self-reported)	0.2	0.2	1.6	-0.0	0.3	-0.2	-0.4	0.3	-0.3	0.2	-0.6	-0.3	-1.3	-0.4	-0.2	-0.7	0.6	-0.1	0.3	-0.1	-0.7	-1.0	-0.4	0.1	0.1	-0.5	0.1
Tense / ‘highly strung’	0.2	0.3	1.7	0.7	0.3	0.3	0.4	0.0	0.3	0.3	-0.7	0.1	-1.3	0.0	-0.2	-0.9	0.7	0.3	0.6	0.2	0.2	-1.0	0.1	0.7	0.8	0.4	1.0
Pulse wave reflection index	0.2	0.2	2.0	-0.4	-0.3	0.2	-0.3	-0.5	-0.3	0.9	-0.1	-0.7	-1.4	-0.7	-0.6	0.2	0.1	-0.1	-0.3	-0.4	0.1	-0.2	0.0	-0.2	-0.4	-0.4	-0.4
Medication: Paracetamol	0.2	0.4	1.1	-0.4	-1.0	-0.6	-0.4	-0.4	-0.8	-0.9	-0.6	-0.1	0.6	0.1	-0.5	-0.8	0.1	-0.7	-0.2	-0.5	-0.5	-1.0	-0.7	-0.2	-0.8	-0.8	-0.6
Birth weight	0.2	0.5	1.7	0.3	1.0	-0.7	-0.4	-0.4	-0.3	-1.3	-0.8	-0.2	-1.1	-0.3	-0.7	-0.3	0.4	-0.6	0.5	-0.0	-1.3	-0.4	-1.1	0.6	0.6	-1.0	0.7
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.1	-0.3	-0.4	-0.2	-0.2	-0.9	-0.2	0.1	-0.4	-0.1	1.0	-0.0	0.1	0.4	-0.6	-0.0	-0.6	-0.6	0.1	-0.4	-0.1	-0.5	-0.7	-0.6	-0.5
Arm fat-free mass (right)	0.2	1.1	4.7	1.6	1.6	0.5	1.0	1.1	0.7	0.3	-0.9	0.0	-0.8	-0.2	0.1	-0.8	1.0	0.6	1.3	1.1	0.6	-0.3	0.2	2.2	2.0	-0.0	1.8
Qualifications: College or University degree	0.2	0.7	3.6	0.4	0.6	1.1	0.6	0.6	1.4	1.9	0.9	-0.0	-0.4	-0.4	0.5	0.5	0.1	0.9	0.2	0.5	0.9	1.4	1.1	0.1	1.1	0.5	0.8
Medication for pain relief, constipation, heartburn	0.2	0.3	0.8	0.5	0.6	0.7	0.3	0.9	0.6	0.5	0.9	-0.1	0.4	-0.2	0.5	0.4	0.6	0.5	0.5	0.6	0.6	0.6	0.5	0.4	0.7	0.4	0.5
Medication: Allopurinol	0.2	0.2	1.7	-0.2	0.2	0.2	0.2	0.2	0.8	0.4	0.8	-0.1	-0.1	-0.2	0.4	0.8	-0.6	0.3	-0.4	0.2	0.5	1.3	0.5	-0.2	0.2	0.4	-0.0
Medication: Omeprazole	0.2	0.2	0.6	0.5	-0.4	0.1	0.4	0.4	0.3	-0.4	-0.3	0.6	0.6	0.8	0.0	-0.3	0.6	0.1	0.7	0.3	-0.1	-0.3	-0.0	0.4	0.5	0.4	0.6
Arm predicted mass (right)	0.2	0.9	4.0	1.5	1.4	0.5	0.9	1.0	0.8	0.5	-0.7	-0.1	-0.8	-0.3	0.1	-0.6	0.8	0.5	1.1	1.1	0.6	-0.3	0.2	2.0	2.0	-0.1	1.7
Leg pain on walking	0.2	0.2	0.8	-0.4	-0.5	0.0	-0.3	-0.2	0.5	0.6	0.2	-0.4	0.6	-0.3	0.3	-0.4	-0.5	0.1	-0.7	-0.2	0.1	0.6	0.3	-0.6	-0.6	-0.9	-0.7
Loneliness, isolation	0.2	0.3	1.0	0.5	0.9	0.2	0.5	-0.1	0.2	-0.4	0.3	0.6	-1.0	0.7	0.2	0.1	0.7	0.3	0.5	0.4	0.5	0.7	0.2	0.3	0.5	0.6	0.4
Ever had bowel cancer screening	0.2	0.2	0.9	0.5	0.9	0.4	0.2	0.6	0.4	0.1	0.4	0.0	-0.9	0.2	-0.1	-0.4	0.9	0.2	0.6	0.5	0.1	-0.4	0.1	0.5	0.8	-0.1	0.7
Smoking status: Current	0.2	0.3	1.4	0.8	0.6	0.1	0.4	0.7	0.2	-0.5	-0.2	0.5	0.1	0.5	0.2	-0.0	1.2	0.3	1.0	0.6	0.1	-0.1	-0.0	1.1	0.5	-0.3	0.5
Whole body water mass	0.2	0.9	3.2	1.3	1.5	0.1	0.5	0.7	0.4	-0.0	-1.5	-0.3	-1.0	-0.6	-0.3	-1.2	0.6	0.2	0.9	0.6	0.1	-1.2	-0.3	1.7	1.8	-0.6	1.5
Number of self-reported non-cancer illnesses	0.2	0.4	1.4	-0.6	-1.2	-0.3	-0.5	0.5	0.2	0.2	0.7	-0.1	-1.2	0.2	-0.2	-0.9	-0.3	-0.5	-0.3	-0.3	-0.7	-0.5	-0.3	-1.0	-1.1	-0.8	-0.9
Ever taken oral contraceptive pill	0.2	0.3	0.7	0.5	0.2	0.7	0.6	0.6	0.4	0.5	0.4	0.5	-0.1	0.3	0.2	0.0	0.9	0.4	0.6	0.6	0.8	0.6	0.4	0.6	0.5	0.3	0.5
Hearing aid user	0.2	0.3	1.3	0.4	0.4	0.2	0.1	1.1	0.2	0.3	0.2	-0.8	-0.5	-0.9	-0.3	0.3	0.7	0.2	0.4	0.5	0.2	-0.8	-0.0	0.7	0.7	-0.2	0.6
High cholesterol (Self-reported)	0.2	0.4	1.1	1.0	0.5	0.7	0.8	0.8	0.4	0.4	0.2	0.5	-0.7	0.8	0.1	0.3	0.9	0.3	0.9	0.6	0.8	1.0	0.6	0.7	0.4	0.5	0.8
Basal metabolic rate	0.2	0.8	3.8	0.5	0.6	-0.5	-0.1	-0.0	-0.4	-0.5	-1.9	-0.9	-1.2	-1.1	-0.8	-1.8	-0.1	-0.4	0.1	-0.1	-0.5	-1.7	-0.9	1.1	1.1	-1.2	0.8
Arm fat-free mass (left)	0.2	1.1	4.1	1.6	1.6	0.7	1.0	1.2	0.8	0.7	-0.7	0.2	-0.6	-0.0	0.3	-0.7	1.1	0.8	1.3	1.1	0.7	-0.3	0.4	2.0	1.9	-0.1	1.7
Myopia	0.2	0.3	2.1	0.4	0.5	0.0	0.2	0.2	-0.1	-0.8	-0.1	1.0	0.3	1.4	0.1	-0.7	0.9	0.0	0.6	-0.1	0.2	-0.1	-0.0	0.2	-1.0	-0.0	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.8	0.4	-0.8	-0.0	0.3	0.2	0.1	-0.5	-0.3	0.6	0.6	0.7	-0.1	-0.2	0.5	-0.1	0.6	0.3	-0.2	-0.9	-0.1	0.4	0.4	0.1	0.5
Pain experienced in last month	0.2	0.3	1.1	0.3	0.4	0.6	0.3	0.9	1.0	0.8	0.3	0.7	0.4	0.7	0.8	0.1	0.2	0.6	0.3	0.3	0.2	0.5	0.6	0.2	-0.0	0.3	0.1
Basal cell carcinoma (self-reported)	0.2	0.3	2.3	-0.4	0.6	-0.2	-0.3	-0.5	-0.5	-0.1	-0.7	-0.4	-1.5	-0.4	-0.3	-1.1	-0.4	-0.3	-0.3	-0.3	0.0	0.5	-0.2	0.3	-0.4	-0.4	-0.5
Pack years of smoking	0.2	0.3	1.2	-0.3	-0.7	-0.4	-0.4	-0.5	-0.5	-0.7	-0.4	0.0	0.0	0.1	-0.1	-0.5	0.0	-0.5	-0.3	-0.4	-0.3	-1.1	-0.6	-0.5	-1.0	-0.7	-0.7
Arm predicted mass (left)	0.2	1.1	4.2	1.6	1.7	0.8	1.1	1.2	1.0	0.8	-0.6	0.3	-0.4	0.1	0.4	-0.5	1.0	0.9	1.3	1.2	0.8	-0.1	0.5	2.1	1.9	0.1	1.7
Bipolar Disorder or Schizophrenia	0.1	0.2	2.1	-0.7	0.6	-0.1	-0.2	-0.1	-0.2	0.2	-0.0	-0.1	-1.4	-0.1	-0.4	0.0	-0.6	-0.1	-0.5	-0.3	0.0	0.3	0.2	-0.9	-0.4	-0.3	-0.6
Crohns Disease (2012)	0.1	0.1	0.6	-0.0	0.0	0.4	0.2	0.1	0.5	0.5	0.3	0.3	0.8	0.0	0.7	-0.0	-0.0	0.7	-0.1	-0.0	0.4	-0.1	0.5	-0.1	-0.3	-0.1	-0.1
HDL Cholesterol	0.1	0.2	1.2	0.2	0.4	0.0	0.2	0.2	0.0	-0.2	-0.1	0.8	1.1	0.9	0.2	-0.5	0.4	-0.0	0.4	0.2	0.0	0.2	-0.0	0.2	-0.4	0.2	-0.3
Rheumatoid Arthritis	0.1	0.2	0.8	-0.5	-0.3	-0.1	-0.4	-0.4	-0.1	0.3	-0.1	-0.1	-0.1	-0.2	-0.1	-0.1	-0.3	-0.0	-0.5	-0.5	-0.2	-0.4	-0.0	-0.7	-0.9	-0.4	-0.8
Schizophrenia (2014)	0.1	0.2	2.4	-0.5	1.0	-0.1	-0.2	0.1	-0.5	-0.1	-0.2	0.1	-1.5	0.0	-0.3	-0.2	-0.1	-0.2	-0.2	-0.2	0.0	0.5	-0.0	-0.7	-0.4	-0.3	-0.5
Heel T-Score	0.1	0.5	8.6	-0.3	0.4	0.1	-0.1	0.4	0.1	0.3	0.6	0.4	0.5	0.4	0.5	0.4	-0.5	0.2	-0.5	-0.0	0.2	2.9	0.3	-0.3	-0.7	0.7	-0.8
Chronotype (morning person)	0.1	0.3	1.5	-0.7	-0.0	-0.3	-0.4	-0.2	0.2	0.0	0.3	-0.2	-1.2	0.1	0.2	-0.9	-0.5	-0.3	-0.5	-0.2	-0.3	0.2	-0.1	-0.9	-0.8	-0.5	-0.9
Hearing difficulty/problems: Yes	0.1	0.1	0.4	0.4	0.5	0.4	0.4	0.1	0.1	0.2	-0.2	-0.1	-0.3	0.2	0.3	-0.6	0.3	0.0	0.3	0.1	0.6	-0.2	0.3	0.4	-0.2	-0.0	0.1
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.6	0.4	0.1	-0.0	0.3	0.1	-0.1	-0.5	-0.0	0.6	0.0	0.8	-0.3	0.3	0.6	-0.0	0.6	0.4	-0.1	0.7	-0.1	0.7	0.2	0.3	0.1
Medication for hormone replacement therapy	0.1	0.1	0.5	0.2	-0.1	0.0	0.2	-0.0	0.6	0.6	0.4	0.0	-0.4	0.3	-0.4	-0.3	0.2	-0.3	0.4	0.6	-0.2	0.6	0.0	0.4	0.6	0.7	0.4
Diabetes (father)	0.1	0.1	0.7	0.3	0.8	0.1	0.3	0.3	-0.2	-0.1	-0.0	0.4	0.0	0.7	0.1	0.8	0.2	0.2	0.3	0.0	0.3	0.3	0.2	0.2	-0.4	0.3	-0.0
Average weekly fortified wine intake	0.1	0.1	1.4	0.0	-0.1	0.2	0.1	-0.2	0.5	0.1	-0.3	0.1	1.2	-0.1	0.4	0.0	-0.4	0.3	-0.1	-0.2	0.3	0.7	0.2	0.1	-0.2	0.3	-0.1
Relative age voice broke	0.1	0.1	1.1	0.1	0.2	0.0	0.1	0.5	0.1	-0.2	0.2	-0.1	-0.2	-0.6	0.2	0.6	-0.1	0.4	-0.1	0.1	0.0	-0.1	0.2	0.2	1.0	0.5	0.5
Qualifications: CSEs or equivalent	0.1	0.1	0.6	0.5	0.2	0.1	0.3	0.0	-0.2	-0.1	-0.4	0.1	0.2	0.1	-0.1	0.4	0.4	0.2	0.4	0.3	0.0	0.2	0.1	0.7	0.6	0.8	0.6
Hayfever, allergic rhinitis or eczema	0.1	0.3	2.1	-0.6	-0.5	-0.4	-0.4	-0.3	-0.2	-0.6	-0.8	-0.5	-1.4	-0.5	-0.7	-1.2	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	-0.2	-0.0	-0.2
Hair/balding pattern: Pattern 2	0.1	0.2	2.1	0.2	-0.0	0.3	0.1	-0.0	0.2	0.6	0.2	0.4	0.4	0.3	0.4	1.5	-0.1	0.6	0.1	0.1	-0.2	0.5	0.4	0.1	0.5	0.3	0.2
Financial difficulties in last 2 years	0.1	0.2	1.1	0.0	0.9	0.4	0.1	-0.1	-0.1	0.8	-0.4	-0.2	-0.8	-0.2	0.3	0.3	-0.0	0.2	-0.0	-0.1	0.1	1.0	0.3	-0.1	0.1	-0.3	0.2
Mouth/teeth dental problems	0.1	0.2	0.5	-0.4	0.6	0.1	-0.2	-0.5	-0.0	0.7	-0.5	-0.4	0.3	-0.5	0.4	-0.0	-0.6	0.2	-0.6	-0.5	0.2	0.2	0.1	-0.0	-0.4	-0.1	-0.5
Time employed in main current job	0.1	0.2	1.3	0.2	-0.8	0.3	0.1	0.4	0.7	-0.0	0.3	0.5	1.1	0.5	0.5	-0.1	0.2	0.4	0.1	0.2	0.2	-0.4	0.4	-0.0	-0.3	-0.1	-0.1
Worrier / anxious feelings	0.1	0.3	1.2	0.7	-1.1	0.1	0.4	-0.0	0.4	-0.2	-0.5	-0.2	-0.5	-0.1	-0.6	-0.4	0.7	0.2	0.6	0.3	0.1	-0.3	0.0	0.7	1.0	0.6	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.7	0.4	0.9	0.2	0.2	0.6	0.2	-0.0	0.2	0.7	-0.4	0.6	0.2	-0.8	0.7	0.3	0.6	0.5	-0.1	0.2	0.0	0.8	0.2	0.1	0.3
Hair/balding pattern: Pattern 3	0.1	0.1	0.5	-0.2	0.7	-0.0	0.1	0.4	0.5	0.2	-0.1	0.1	0.7	-0.0	0.6	-0.0	-0.6	0.2	-0.4	-0.1	0.0	0.3	0.1	-0.0	-0.3	0.2	-0.1
Number of live births	0.1	0.1	0.6	-0.1	0.4	-0.2	0.1	-0.2	-0.1	-0.3	-0.0	0.1	-0.3	-0.0	0.1	0.1	-0.7	-0.0	-0.4	-0.3	0.1	0.8	-0.0	-0.3	-0.1	0.5	0.1
Hair/balding pattern: Pattern 4	0.1	0.2	1.0	0.2	-0.3	-0.3	0.0	0.1	-0.6	-0.3	0.1	0.2	-1.0	0.2	-0.5	-0.4	0.2	-0.6	0.4	0.3	-0.3	-0.7	-0.5	0.2	0.3	0.2	0.6
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.8	-0.5	-0.1	0.0	-0.3	-0.5	-0.1	0.9	-0.1	-0.5	-0.4	-0.9	-0.1	-0.3	-0.4	-0.0	-0.3	-0.3	0.0	-0.4	0.0	-0.2	-0.3	-0.5	-0.3
Blood clot in the leg (DVT)	0.1	0.1	0.8	-0.2	-0.6	-0.2	-0.1	-0.2	-0.3	-0.5	0.1	-0.2	-0.6	-0.1	-0.3	0.1	-0.1	-0.2	-0.1	-0.1	-0.2	-0.9	-0.1	-0.1	-0.2	-0.2	-0.1
Headache pain in last month	0.1	0.2	1.4	-0.0	-0.4	0.5	0.2	-0.1	0.2	1.2	0.3	-0.4	0.0	-0.3	0.0	0.9	0.0	0.3	-0.1	0.1	0.5	0.2	0.5	-0.1	0.2	-0.1	0.2
Comparative body size at age 10	0.1	0.2	1.0	-0.2	-0.1	-0.3	-0.4	-0.7	0.0	-0.8	-1.0	-0.1	-0.2	-0.0	-0.2	-0.3	0.1	-0.2	-0.0	-0.6	-0.2	-0.2	-0.3	-0.2	-0.6	-0.9	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.8	-0.5	0.2	-0.1	-0.2	-0.3	-0.1	0.9	-0.1	-0.1	-0.9	-0.2	0.2	0.1	-0.8	-0.1	-0.5	-0.2	-0.3	0.5	0.0	-0.4	-0.3	-0.2	-0.3
Health satisfaction	0.1	0.1	1.3	-0.0	-0.1	0.2	-0.0	0.1	0.6	0.7	0.1	-0.2	-0.3	-0.2	0.2	-1.1	0.3	0.2	0.1	0.2	0.1	-0.4	0.2	-0.1	-0.2	-0.8	-0.0
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.5	0.1	-0.3	0.3	0.0	-0.2	0.1	0.4	0.2	0.0	0.4	0.1	0.0	-0.1	0.4	0.0	0.2	0.1	0.2	-0.7	0.1	0.1	-0.5	-0.6	-0.2
Mean time to correctly identify matches	0.1	0.2	1.5	0.0	-0.6	-0.5	0.0	-0.5	-0.3	-1.2	-0.1	0.1	-0.9	0.1	-0.3	-0.6	-0.4	-0.2	-0.2	-0.1	-0.3	-0.5	-0.4	-0.2	0.1	0.7	0.2
Knee pain experienced in last month	0.1	0.2	1.2	0.4	-0.3	0.3	0.4	0.1	0.3	0.5	0.4	0.3	0.5	0.1	0.3	1.1	0.2	0.4	0.3	0.6	0.1	0.0	0.4	0.3	0.7	1.0	0.7
Whole body fat-free mass	0.1	0.8	2.8	1.2	1.4	0.0	0.5	0.6	0.3	-0.0	-1.6	-0.4	-0.9	-0.6	-0.4	-1.2	0.5	0.1	0.8	0.5	0.0	-1.2	-0.3	1.6	1.7	-0.7	1.4
Long-standing illness, disability or infirmity	0.1	0.2	0.7	0.4	0.1	0.3	0.4	0.4	0.6	0.0	-0.2	0.9	-0.4	0.9	0.5	-0.3	0.5	0.4	0.4	0.1	0.5	-0.1	0.4	-0.1	-0.3	-0.1	0.1
Osteoarthritis (self-reported)	0.1	0.2	0.5	-0.5	0.6	-0.2	-0.4	0.1	-0.3	0.2	0.2	-0.2	-0.7	-0.1	-0.2	-0.7	-0.3	-0.5	-0.3	-0.1	-0.3	0.6	-0.2	-0.2	-0.6	-0.7	-0.5
Medication: Gliclazide	0.1	0.1	0.8	0.4	-0.9	-0.0	0.2	0.0	0.2	-0.2	-0.6	-0.0	0.3	0.2	-0.3	0.5	0.3	-0.1	0.2	0.1	0.0	0.0	-0.1	0.1	0.1	0.3	0.4
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.7	0.5	0.3	0.3	0.5	-0.3	-0.1	-0.2	-0.1	0.5	-0.4	0.7	-0.0	0.1	0.5	0.2	0.5	0.3	0.5	0.0	0.2	0.8	0.5	0.2	0.4
Commuting to job workplace: Public transport	0.1	0.2	0.6	0.2	-0.1	-0.3	-0.1	-0.4	-0.8	-0.7	-0.5	-0.1	-0.6	-0.1	-0.6	0.6	0.2	-0.3	0.1	-0.1	-0.5	-0.0	-0.4	0.3	0.7	-0.4	0.5
Number of operations (self-reported)	0.1	0.2	0.7	-0.5	-0.0	-0.3	-0.5	-0.3	-0.6	0.2	-0.4	-0.5	-0.3	-0.3	-0.7	-0.2	-0.3	-0.5	-0.3	-0.3	-0.5	-0.2	-0.4	0.0	-0.4	-0.8	-0.4
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.1	0.4	-0.3	0.2	-0.0	-0.1	0.0	-0.1	0.3	0.1	-0.1	0.1	-0.1	0.4	0.5	-0.6	0.0	-0.5	-0.1	-0.1	0.1	0.1	-0.1	-0.1	0.2	-0.2
Hair Pigment	0.0	0.4	2.7	-0.0	-0.4	0.5	0.2	0.4	0.7	0.8	1.2	0.6	1.6	0.4	1.1	-0.0	-0.3	0.5	-0.3	0.4	0.6	-0.6	0.7	-0.2	-0.3	0.6	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.3	0.0	-0.2	0.0	0.2	0.1	-0.1	-0.2	0.4	-0.0	-0.3	0.1	-0.0	0.3	0.1	0.1	0.2	0.2	0.2	-0.5	0.2	0.1	0.2	0.1	0.1

Hub : Genes

MRPL23-AS1

Models

Trait associations