TWAS hub - LOC100133545

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0372	0.0165	7.1e-07	0.019	0.030	0.031	NA	0.024	6.2e-05	7.5e-07	4.4e-07	NA	7.0e-06
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0344	0.0186	1.3e-03	0.005	0.023	0.008	NA	-0.001	7.6e-02	1.2e-03	3.6e-02	NA	5.0e-01
3	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0560	0.0320	2.0e-03	0.019	0.031	0.009	NA	0.021	2.7e-02	6.7e-03	9.6e-02	NA	2.2e-02
4	TCGA	Brain Lower Grade Glioma	0.0512	0.0262	1.6e-05	0.040	0.045	0.031	NA	0.035	2.2e-05	7.1e-06	1.8e-04	NA	6.6e-05
5	TCGA	Lung Adenocarcinoma	0.0953	0.0438	1.3e-03	0.009	0.022	0.017	NA	0.007	2.7e-02	1.2e-03	3.5e-03	NA	4.8e-02
6	TCGA	Lung Squamous Cell Carcinoma	0.0316	0.0203	9.5e-03	0.006	0.013	0.003	NA	0.009	5.7e-02	1.1e-02	1.4e-01	NA	3.2e-02
7	TCGA	Pheochromocytoma and Paraganglioma	0.0750	0.0470	2.0e-03	0.049	0.059	0.008	NA	0.032	4.9e-03	2.2e-03	1.5e-01	NA	2.0e-02
8	TCGA	Prostate Adenocarcinoma	0.0584	0.0341	7.3e-04	-0.002	0.023	-0.002	NA	0.002	5.4e-01	1.5e-03	7.4e-01	NA	1.7e-01
9	TCGA	Thyroid Carcinoma	0.0870	0.0390	1.7e-06	0.090	0.062	0.091	NA	0.086	4.3e-09	1.1e-06	3.8e-09	NA	1.1e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Breast Cancer	18.0	43.3	64.3	6.5	5.7	7.5	6.9	4.8	8.0	6.0	5.7	7.4
Medication: Blood pressure	11.5	22.0	32.1	5.2	4.4	5.4	4.7	3.7	5.7	4.2	4.1	4.5
Systolic Blood Pressure	10.6	52.8	114.5	6.9	6.0	7.9	6.7	5.1	10.7	5.8	6.0	8.6
Medication: Bendroflumethiazide	8.9	13.5	23.3	3.6	3.8	4.1	3.1	2.0	4.8	3.3	3.3	4.4
Medication: Lisinopril	7.8	10.1	14.8	3.0	3.7	3.6	3.1	1.4	3.8	3.4	3.2	2.6
Hypertension (Self-reported)	7.6	21.1	39.4	4.2	4.5	5.2	4.2	2.7	6.3	4.3	4.4	4.7
High blood pressure	6.5	18.0	36.4	4.0	3.9	4.8	4.0	2.2	6.0	3.9	4.0	4.5
Friendships satisfaction	6.0	7.4	9.5	2.6	2.9	3.1	2.8	2.4	2.3	3.1	2.5	2.7
Number of incorrect matches in round	5.3	8.8	10.9	2.8	3.3	3.2	3.2	2.4	2.2	3.3	2.8	3.2
Medication: Atenolol	4.9	6.1	8.6	2.9	2.2	2.8	2.6	2.3	2.8	2.1	2.0	2.5
High blood pressure (mother)	4.7	6.7	15.4	2.7	2.0	2.2	2.1	3.9	2.9	1.4	1.3	3.4
Eye problems/disorders: None of the above	4.7	5.4	7.2	2.3	2.6	2.7	2.4	2.2	2.2	2.5	2.2	1.8
Cardiovascular Disease	4.6	15.2	35.3	3.3	3.9	4.1	3.4	2.0	5.9	3.4	3.7	4.3
Vascular/heart problems diagnosed by doctor	4.6	12.6	27.7	-3.1	-3.2	-4.0	-3.1	-1.6	-5.3	-3.2	-3.1	-4.1
Illnesses of mother	4.5	5.5	9.8	-2.6	-1.7	-2.2	-1.9	-3.0	-3.0	-1.4	-1.4	-3.1
Medication for cholesterol	4.5	6.8	11.6	-3.4	-1.9	-3.0	-2.6	-2.4	-3.2	-1.9	-1.6	-2.8
Systolic blood pressure, automated reading	4.4	12.7	33.8	3.4	2.5	3.9	2.8	2.7	5.8	2.3	2.3	4.7
Illnesses of father: High blood pressure	4.3	5.4	7.0	2.2	2.6	2.6	2.6	1.2	2.4	2.5	2.4	2.0
Medication: Amlodipine	4.1	5.7	13.9	2.4	1.5	2.7	2.1	1.7	3.7	1.9	1.4	3.0
Medication: Ramipril	3.8	4.9	7.1	1.9	2.3	2.4	2.3	0.8	2.5	2.4	2.7	2.2
High blood pressure (siblings)	3.8	5.5	10.6	2.2	2.1	2.4	2.2	1.8	2.8	1.9	2.0	3.2
Respiratory disease	3.7	8.3	12.6	-2.7	-3.5	-3.2	-3.6	-1.0	-2.5	-3.4	-3.5	-1.1
Supplements: Zinc	3.6	4.0	6.8	2.4	1.5	2.2	2.0	2.2	1.7	1.8	1.0	2.6
Loud music exposure frequency	3.6	3.9	7.1	1.8	1.8	2.1	1.6	2.7	2.5	1.5	1.6	2.0
Medication: Seretide 50 evohaler	3.6	4.2	6.5	-1.9	-2.5	-2.5	-2.4	-1.8	-1.7	-2.1	-1.5	-1.6
Happiness	3.5	4.2	5.4	2.2	2.1	2.2	2.1	1.7	1.8	2.2	1.9	2.3
Breast cancer (self-reported)	3.5	4.2	6.7	-2.6	-1.4	-2.2	-2.1	-2.2	-1.8	-2.0	-1.2	-2.5
Age when periods started (menarche)	3.3	7.8	11.8	-3.1	-2.6	-2.9	-2.6	-3.4	-2.5	-2.3	-2.1	-3.3
Medication: Blood pressure	3.3	5.8	12.1	1.6	2.6	2.5	2.0	1.1	3.5	2.2	2.8	2.6
Type 2 Diabetes (T2D) (2012)	3.2	3.6	4.8	1.8	2.1	2.0	2.0	1.4	1.9	1.9	1.7	2.2
Falls in the last year	3.2	4.4	8.7	3.0	1.5	2.3	2.1	2.5	1.2	2.0	1.1	2.4
Wheeze or whistling in the chest in last year	3.1	5.6	7.8	-2.4	-2.7	-2.4	-2.5	-2.2	-2.1	-2.4	-2.8	-1.3
Mean Putamen Volume	3.0	3.4	5.4	1.9	2.0	2.1	1.9	1.4	1.6	2.3	1.6	1.5
Primary Biliary Cirrhosis	2.9	4.1	7.8	2.8	1.4	2.1	2.1	2.6	1.6	1.8	1.4	1.8
Trunk fat percentage	2.9	11.8	29.2	-3.6	-2.8	-3.2	-3.0	-5.4	-2.3	-2.7	-2.1	-4.5
Arm fat percentage (left)	2.9	11.6	20.0	-3.5	-3.1	-3.3	-3.3	-4.5	-2.3	-3.3	-2.6	-4.2
Ever had stillbirth, spontaneous miscarriage or termination	2.5	2.7	4.7	-2.2	-1.4	-1.8	-1.7	-1.4	-1.3	-1.6	-1.0	-2.0
Mineral and other dietary supplements	2.5	3.4	6.0	-1.9	-2.4	-2.0	-2.0	-0.9	-1.3	-2.1	-2.2	-1.0
Arm fat percentage (right)	2.4	9.5	16.0	-3.2	-2.8	-3.0	-3.0	-4.0	-2.0	-3.0	-2.3	-3.9
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	7.0	1.6	2.2	1.7	1.1	2.6	0.9	1.7	1.6	1.6
Eye problems/disorders: Cataract	2.4	2.8	3.5	-1.7	-1.7	-1.8	-1.9	-1.8	-1.3	-1.6	-1.7	-1.5
Asthma	2.3	4.6	6.9	-2.3	-2.6	-2.5	-2.6	-1.2	-1.6	-2.5	-2.3	-0.9
Diverticular disease/diverticulitis (self-reported)	2.2	2.6	7.0	-1.7	-1.5	-1.4	-1.5	-2.6	-0.8	-1.5	-1.2	-1.6
Other serious medical condition/disability diagnosed by doctor	2.1	2.7	6.5	1.6	1.5	1.7	1.2	2.6	0.9	1.5	1.0	2.2
Medication: Co-codamol	2.1	2.5	5.4	-2.2	-1.2	-1.8	-1.5	-2.3	-1.1	-1.3	-0.6	-1.4
Body fat percentage	2.1	8.3	20.1	-2.9	-2.5	-2.6	-2.6	-4.5	-1.6	-2.5	-2.0	-3.6
Exposure to tobacco smoke outside home	2.1	2.8	4.8	-2.0	-1.4	-1.7	-1.7	-2.0	-2.2	-1.2	-1.0	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.1	2.5	9.4	-1.8	-0.8	-1.5	-1.2	-3.1	-0.7	-1.0	-0.4	-1.9
Asthma (self-reported)	2.1	4.2	7.0	-2.0	-2.6	-2.4	-2.5	-0.8	-1.6	-2.4	-2.5	-0.5
Fasting Glucose	2.0	2.4	5.1	2.0	1.0	1.9	2.2	1.1	0.4	2.1	0.9	1.3
Medication: Lansoprazole	2.0	2.2	5.8	-1.6	-1.4	-1.5	-1.4	-2.4	-0.9	-1.2	-1.0	-1.6
Medication: Ventolin 100micrograms inhaler	2.0	2.6	3.7	-1.8	-1.9	-1.9	-1.7	-1.2	-1.6	-1.6	-1.6	-0.7
Illnesses of father: Heart disease	2.0	2.7	4.8	1.2	2.2	1.6	1.7	1.0	1.9	1.6	1.7	1.6
Supplements: Fish oil (including cod liver oil)	2.0	2.6	4.7	1.5	2.2	1.8	1.9	0.7	1.2	1.8	1.9	0.6
Irritable Bowel Disease (IBD)	1.9	4.5	6.6	1.7	2.1	2.5	2.4	0.9	2.2	2.1	2.2	2.6
Trunk fat mass	1.9	8.2	25.4	-2.6	-2.2	-2.5	-2.1	-5.0	-2.1	-2.1	-1.5	-3.9
Peak expiratory flow (PEF)	1.9	4.3	9.5	-1.9	-1.6	-2.4	-2.2	-2.0	-2.0	-1.9	-1.1	-3.1
Chronic bronchitis/emphysema (father)	1.8	2.1	6.0	-2.0	-0.6	-1.4	-1.7	-2.5	-1.1	-1.1	-0.7	-0.8
Ever highly irritable/argumentative for 2 days	1.7	2.1	4.3	1.8	1.4	1.5	0.9	2.1	1.7	1.0	0.6	1.4
Overall health rating	1.7	3.6	7.4	1.2	2.4	2.3	1.9	0.1	1.7	2.4	2.7	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.1	3.6	-0.8	-1.5	-1.4	-0.9	-1.9	-1.6	-1.4	-1.5	-1.5
Irritability	1.7	2.8	3.3	1.8	1.8	1.8	1.7	1.7	1.8	1.7	1.3	1.4
Arm fat mass (right)	1.6	6.6	15.2	-2.3	-2.3	-2.4	-2.2	-3.9	-1.9	-2.3	-1.8	-3.4
Average weekly red wine intake	1.6	2.4	4.5	-2.1	-1.5	-1.7	-1.6	-1.6	-1.0	-1.7	-1.5	-1.0
Waist circumference	1.5	5.5	11.7	-1.9	-2.3	-2.2	-2.2	-3.4	-1.5	-2.4	-1.7	-2.8
Allergy	1.5	3.4	5.6	1.6	2.4	2.1	2.2	0.6	2.0	1.9	2.2	0.7
Impedance of arm (left)	1.5	7.2	15.3	-3.9	-1.3	-2.7	-2.6	-3.6	-2.4	-1.4	-1.1	-3.4
Medication for cholesterol, blood pressure or diabetes	1.5	2.5	4.9	-0.6	-2.1	-1.5	-1.1	-0.0	-2.2	-1.5	-2.1	-1.8
Whole body fat mass	1.5	6.3	18.2	-2.2	-2.2	-2.2	-2.0	-4.3	-1.7	-2.0	-1.6	-3.3
Family relationship satisfaction	1.5	1.8	5.3	1.2	0.9	1.2	0.8	2.3	1.2	0.8	0.1	2.1
Risk taking	1.5	2.1	4.3	-1.2	-2.1	-1.4	-1.5	-0.9	-1.5	-1.3	-1.9	-1.0
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	7.9	-0.3	-1.9	-0.9	-1.4	1.4	-1.4	-1.3	-2.8	0.2
Depression (Nagel 2018)	1.3	2.0	3.0	1.7	1.7	1.6	1.2	0.8	1.6	1.5	1.5	0.5
Stomach or abdominal pain in last month	1.3	1.7	3.1	-1.8	-0.9	-1.5	-1.4	-1.5	-1.3	-1.0	-0.5	-1.3
Nervous feelings	1.3	2.4	3.3	1.3	1.8	1.6	1.5	1.2	1.7	1.6	1.8	1.4
Age at first live birth	1.3	2.3	5.0	-0.6	-2.0	-1.6	-1.6	0.5	-1.0	-2.0	-2.2	-0.7
Age at last live birth	1.3	1.9	4.9	-0.5	-1.7	-1.4	-1.4	0.4	-1.0	-1.8	-2.2	-0.5
Commuting to job workplace: Car/motor vehicle	1.3	1.5	6.4	-1.7	-0.5	-1.0	-0.7	-2.5	0.4	-0.6	0.5	-1.3
Illnesses of siblings: Diabetes	1.3	1.6	2.1	-1.3	-1.2	-1.4	-1.3	-1.3	-1.3	-1.3	-0.9	-1.4
Arm fat mass (left)	1.3	5.5	15.0	-2.0	-2.0	-2.0	-1.8	-3.9	-1.6	-2.0	-1.4	-3.2
Medication: Levothyroxine sodium	1.2	2.1	3.6	0.8	1.8	1.4	1.5	0.1	1.7	1.7	1.9	1.2
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.1	-1.0	-1.2	-1.4	-0.7	-1.1	-1.8	-1.0	-1.3	-0.7
Lung cancer (father)	1.2	1.4	5.4	0.5	0.8	1.1	0.4	0.5	1.8	0.5	1.0	2.3
Number of children fathered	1.2	1.4	5.1	-1.2	-0.9	-0.9	-0.9	-2.3	-0.6	-0.6	-0.5	-1.6
Chest pain or discomfort	1.2	1.7	4.7	-2.2	-0.4	-1.5	-1.6	-2.1	-0.7	-0.5	-0.3	-0.5
Supplements: Vitamin C	1.2	1.4	2.0	-1.0	-1.4	-1.1	-1.4	-1.2	-0.2	-1.3	-1.3	-1.2
Osteoporosis (self-reported)	1.2	1.5	3.4	1.3	1.0	1.2	1.2	0.7	1.2	1.2	0.9	1.9
Miserableness	1.2	2.0	3.1	-1.0	-1.8	-1.6	-1.2	-0.8	-1.6	-1.7	-1.8	-1.0
Mother’s age at death	1.2	1.5	2.9	1.6	0.4	1.4	1.3	1.7	1.5	0.9	0.4	1.1
Eye problems/disorders: Glaucoma	1.2	1.4	3.1	-0.6	-1.8	-1.0	-1.0	-0.6	-1.3	-1.3	-1.4	-0.9
Pain type(s) experienced in last month: Hip pain	1.2	1.5	3.9	0.8	1.6	1.3	1.1	0.9	1.1	1.3	2.0	0.5
Alcohol drinker status: Previous	1.2	1.3	3.6	0.0	-0.9	-0.6	-1.1	1.5	-1.9	-0.5	-1.6	-1.0
Crohns Disease (2017)	1.1	2.4	6.6	1.3	1.1	1.9	1.4	0.6	2.6	1.0	1.2	2.0
Qualifications: A levels/AS levels or equivalent	1.1	2.4	4.6	2.0	1.3	1.7	1.5	2.1	1.1	1.4	0.9	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	2.6	1.3	1.5	1.4	1.4	1.4	0.4	1.6	1.2	1.1
Number of full sisters	1.1	1.4	2.6	-1.1	-1.2	-1.2	-1.3	-1.6	-0.9	-1.4	-0.9	-0.6
Diabetes diagnosed by doctor	1.1	1.9	3.4	1.6	1.6	1.5	1.5	0.3	1.4	1.3	1.8	0.3
Alcohol drinker status: Never	1.1	1.3	3.0	1.2	1.0	1.2	1.7	0.2	0.5	1.4	1.5	0.8
Leg fat percentage (left)	1.1	4.0	8.5	-1.9	-1.9	-1.9	-2.2	-2.9	-0.3	-2.2	-1.7	-1.9
Diabetes (self-reported)	1.0	1.5	3.0	1.3	1.7	1.3	1.3	0.6	1.0	1.2	1.7	-0.0
Impedance of arm (right)	1.0	4.9	11.2	-3.4	-0.8	-2.2	-2.1	-3.0	-1.9	-1.0	-0.6	-2.9
Alcohol intake versus 10 years previously	1.0	1.5	2.4	1.5	1.6	1.1	1.1	1.5	0.3	1.4	1.3	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.2	8.6	-1.6	-1.1	-1.7	-1.4	-2.9	-1.4	-1.1	-0.2	-2.9
Glaucoma (self-reported)	1.0	1.2	2.1	-0.8	-1.4	-1.0	-0.9	-1.1	-1.5	-0.9	-0.8	-1.2
Emphysema/chronic bronchitis	1.0	1.1	3.7	-1.1	-0.7	-1.1	-1.9	-0.1	-0.3	-1.4	-1.2	-0.7
Migraine (self-reported)	1.0	1.2	2.0	-1.4	-0.9	-1.2	-1.0	-1.1	-1.2	-1.3	-0.3	-1.1
Comparative height size at age 10	1.0	5.3	10.0	2.2	2.8	2.4	2.9	-1.0	0.8	3.2	3.0	0.6
Had major operations	1.0	1.2	3.5	1.5	0.7	1.1	1.0	1.9	0.5	0.9	0.6	1.0
Fed-up feelings	0.9	1.6	2.3	1.1	1.2	1.5	1.3	0.2	1.2	1.4	1.5	1.2
Fluid intelligence score	0.9	1.9	2.8	1.2	1.7	1.2	1.4	1.3	1.2	1.3	1.4	1.4
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	4.0	0.3	2.0	1.1	1.1	-0.5	1.5	1.4	1.8	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	2.0	3.3	-1.2	-1.5	-1.4	-1.5	-0.7	-1.6	-1.4	-1.3	-1.8
Leg fat mass (left)	0.9	3.6	11.9	-1.6	-1.7	-1.6	-1.5	-3.5	-1.0	-1.6	-1.2	-2.3
Alzheimer’s Disease (in father)	0.8	0.9	2.8	-1.2	-0.9	-0.8	-0.7	-1.7	-0.6	-0.6	-0.7	-0.7
Prostate Cancer	0.8	1.2	2.5	1.6	-0.1	0.9	1.4	1.6	-0.1	0.8	-0.3	1.4
Blood Platelet Count	0.8	8.8	12.7	-3.6	-3.0	-3.0	-2.9	-2.5	-3.3	-2.8	-2.5	-2.9
Hypothyroidism (self reported)	0.8	1.9	5.4	-0.2	2.0	0.9	1.2	-1.2	1.3	1.3	2.3	0.8
Angina	0.8	1.0	1.7	-1.2	-1.1	-1.1	-0.9	-1.3	-0.7	-0.9	-0.8	-1.1
Medication: Metformin	0.8	1.1	3.6	1.9	0.7	1.2	1.2	1.1	0.7	0.8	0.6	0.2
Maternal smoking around birth	0.8	1.2	7.1	-1.4	0.1	-0.6	-0.5	-2.7	0.5	-0.2	0.8	-0.5
Medication: Cholesterol lowering	0.8	1.2	3.1	0.3	1.8	1.0	0.7	-0.6	0.9	1.3	1.7	0.7
Prospective memory result	0.8	1.0	1.7	-1.2	-1.0	-0.7	-1.3	-1.0	-0.7	-0.9	-1.3	-0.7
Gout (self-reported)	0.8	1.1	2.1	-1.1	-1.3	-0.9	-1.0	-1.5	-0.2	-1.1	-1.2	-0.3
Forced vital capacity (FVC), Best measure	0.8	3.1	10.6	-1.3	-0.8	-1.3	-0.8	-3.2	-1.6	-0.7	0.0	-3.0
Number of full brothers	0.8	1.0	1.8	1.2	0.8	1.1	1.1	1.4	0.4	1.2	0.8	0.2
Leg fat mass (right)	0.8	3.2	11.0	-1.5	-1.5	-1.5	-1.3	-3.3	-1.0	-1.5	-1.0	-2.2
Illnesses of father: None of the above (group 1)	0.8	1.0	2.4	0.2	-1.6	-0.4	-0.8	0.8	-1.1	-0.9	-1.5	-0.8
Commuting to job workplace: Cycle	0.8	1.0	1.7	-1.3	-0.8	-1.1	-1.3	-0.3	-1.1	-1.0	-0.6	-1.1
Ulcerative Colitis	0.7	1.0	1.9	0.7	1.4	1.1	1.2	1.1	0.4	1.2	1.2	0.0
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.8	1.2	1.4	1.1	1.4	-0.6	1.0	1.3	1.7	-0.1
Frequency of depressed mood in last 2 weeks	0.7	0.9	1.6	0.9	1.2	1.2	1.0	-0.0	0.5	1.1	1.3	-0.6
Relative age of first facial hair	0.7	1.4	4.7	1.3	0.3	1.3	1.1	2.2	0.9	0.9	0.3	1.5
Body mass index (BMI)	0.7	3.1	4.9	-1.1	-2.0	-1.6	-1.8	-2.2	-0.6	-2.1	-1.8	-2.1
Had other major operations	0.7	0.8	3.1	-0.9	-0.5	-0.6	-0.8	-0.4	-1.3	-0.4	-0.6	-1.8
Hip circumference	0.7	3.0	11.4	-1.1	-1.7	-1.3	-1.0	-3.4	-0.7	-1.4	-1.0	-2.2
Father’s age at death	0.7	0.9	3.0	-0.4	-1.0	-0.8	-0.9	0.1	-1.2	-1.0	-1.7	-0.4
Leg fat percentage (right)	0.7	2.7	7.3	-1.6	-1.4	-1.5	-1.7	-2.7	-0.1	-1.7	-1.2	-1.7
Angina (self-reported)	0.7	0.9	1.9	-1.0	-1.1	-0.9	-0.7	-1.4	-0.5	-0.8	-0.7	-1.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	1.6	-1.0	-1.2	-1.0	-1.2	-0.7	-0.1	-1.3	-1.0	-0.2
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.0	1.0	1.4	0.8	0.9	0.2	0.4	1.2	1.1	-0.2
Ever had bowel cancer screening	0.7	0.8	2.3	0.1	1.1	1.1	0.7	0.2	-0.1	1.5	1.2	0.9
Supplements: Calcium	0.7	0.8	3.5	1.0	0.3	1.0	0.5	1.9	0.2	0.5	-0.1	1.1
Ulcerative Colitis (UC)	0.6	1.2	2.5	0.7	1.2	1.1	1.4	-0.0	0.4	1.3	1.6	1.3
Age at First Birth	0.6	0.9	2.4	1.4	0.5	0.9	1.0	1.6	0.3	0.7	0.2	0.9
Neuroticism (2016)	0.6	0.8	2.0	-0.8	-0.6	-1.0	-0.7	-1.2	-1.0	-0.4	-0.1	-1.4
Current tobacco smoking	0.6	1.0	2.1	0.6	1.4	1.0	1.1	0.6	-0.1	1.5	1.5	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	2.4	-0.9	-1.4	-1.2	-1.0	-0.3	-1.4	-1.4	-1.5	-0.3
Hearing difficulty/problems with background noise	0.6	1.0	3.1	0.9	1.1	0.7	0.9	1.8	-0.4	1.1	0.5	0.9
Heart attack	0.6	0.7	4.4	-1.1	0.2	-0.5	-0.3	-2.1	0.2	-0.2	0.6	-0.2
Illnesses of siblings	0.6	0.8	3.6	-0.4	-0.6	-0.6	-0.3	-0.2	-1.9	-0.2	-0.7	-1.5
Weight	0.6	2.7	12.3	-0.7	-1.1	-1.1	-0.5	-3.5	-1.4	-0.8	-0.5	-2.5
Trunk predicted mass	0.6	3.4	7.6	2.3	1.8	1.8	2.8	-0.5	0.3	2.2	2.3	0.8
Breastfed as a baby	0.6	0.8	1.8	1.4	0.2	1.0	0.8	1.1	1.1	0.3	0.4	0.9
Birth weight of first child	0.6	1.1	2.6	0.5	1.5	0.8	1.2	0.5	-0.9	1.4	1.6	-0.0
Medication: Allopurinol	0.6	0.7	1.7	-0.6	-1.3	-0.3	-0.6	-1.3	0.7	-0.6	-1.2	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.7	-0.4	0.2	-0.3	0.6	-1.9	-1.0	0.9	1.5	-1.4
Average weekly champagne plus white wine intake	0.6	0.8	2.0	0.9	0.4	1.0	0.7	0.8	1.4	0.4	0.2	1.3
Wears glasses or contact lenses	0.6	0.7	3.6	-1.0	-0.5	-0.5	-0.4	-1.9	-0.7	-0.4	-0.4	-0.6
Fractured/broken bones in last 5 years	0.6	0.7	1.6	-0.3	-1.3	-0.8	-0.9	0.5	-1.0	-1.1	-1.1	-0.1
Basal cell carcinoma (self-reported)	0.6	0.7	4.8	-0.8	-0.0	-0.1	0.1	-2.2	0.4	0.0	0.7	-0.5
Heart attack/myocardial infarction (self-reported)	0.6	0.8	4.9	-1.2	0.2	-0.5	-0.3	-2.2	0.3	-0.2	0.6	-0.2
Neuroticism (Nagel 2018)	0.5	1.1	2.8	1.3	1.0	1.1	1.0	1.7	0.3	1.1	0.9	0.6
Schizophrenia (2018)	0.5	1.0	2.2	-0.8	-1.5	-1.0	-1.0	-0.4	-0.7	-1.3	-1.4	0.0
Lupus	0.5	0.8	2.7	-0.8	-0.9	-0.8	-0.8	-0.5	-1.6	-0.6	-0.5	-1.1
Blood Red Count	0.5	5.0	10.8	-2.0	-2.2	-2.3	-1.9	-0.8	-3.3	-1.9	-2.5	-2.6
Hand grip strength (left)	0.5	1.3	3.1	1.7	0.3	1.2	1.1	1.2	1.3	0.3	0.4	1.4
Alcohol usually taken with meals	0.5	0.9	1.8	-0.3	-0.8	-0.5	-1.1	1.2	0.7	-1.3	-1.3	-0.2
Forced vital capacity (FVC)	0.5	2.1	11.1	-0.9	0.1	-0.5	0.0	-3.3	-0.7	0.0	1.1	-2.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.8	-0.4	-1.3	-0.7	-0.6	-0.4	-0.9	-1.0	-0.8	-0.6
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	5.0	0.7	0.2	0.3	0.2	2.2	0.1	0.1	0.3	0.7
Medication: Simvastatin	0.5	0.7	1.6	0.6	1.3	0.9	0.5	0.3	1.1	0.9	1.0	0.0
Trunk fat-free mass	0.5	3.1	7.1	2.2	1.7	1.7	2.7	-0.5	0.3	2.1	2.2	0.8
Pulse wave Arterial Stiffness index	0.5	0.6	2.6	-0.8	-0.4	-0.7	-0.5	-1.6	-0.3	-0.9	-0.4	-0.2
Pulse wave reflection index	0.5	0.6	3.6	-0.6	-0.6	-0.5	-0.3	-1.9	0.2	-0.8	-0.4	0.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.2	0.9	0.9	0.7	0.7	1.5	0.1	0.8	0.5	0.6
Pulse wave peak to peak time	0.5	0.5	2.1	0.7	0.5	0.6	0.6	1.4	0.0	1.0	0.6	-0.1
Shortness of breath walking on level ground	0.5	0.5	1.0	-0.5	-0.7	-0.6	-1.0	-0.5	0.1	-0.9	-0.9	1.0
Medication: Ibuprofen	0.5	0.5	1.5	-0.9	-0.7	-0.6	-0.4	-0.2	-1.1	-0.4	-0.3	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.1	1.0	0.4	0.8	0.9	0.5	0.3	1.1	0.3	1.0
Smoking status: Current	0.5	0.8	1.7	0.6	1.3	0.9	0.9	0.8	-0.2	1.3	1.2	0.1
Age started oral contraceptive pill	0.5	0.6	0.9	-0.8	-1.0	-0.9	-0.8	-0.6	-0.6	-0.9	-0.6	-0.6
Unable to work because of sickness or disability	0.5	0.7	1.6	-0.1	1.1	0.4	0.6	-0.3	-0.6	1.1	1.3	-1.0
Myopia	0.5	0.7	2.4	0.7	1.5	0.4	0.6	0.5	0.5	0.8	1.3	0.5
HDL Cholesterol	0.4	0.6	1.9	0.1	1.0	0.4	0.7	-1.0	0.4	0.9	1.4	-0.3
LDL Cholesterol	0.4	0.6	2.4	-1.5	0.7	-0.6	-0.4	-1.3	0.1	-0.0	0.7	-0.2
Blood White Count	0.4	2.7	5.5	-1.1	-2.3	-1.4	-1.0	-1.0	-2.3	-1.5	-1.5	-2.1
BMI	0.4	2.4	5.3	-1.0	-1.9	-1.4	-1.3	-2.3	-0.4	-1.8	-1.3	-1.6
Height	0.4	8.5	17.5	1.1	2.1	0.8	2.6	-4.2	-3.6	3.4	3.3	-3.3
Average weekly spirits intake	0.4	0.5	3.6	-0.5	0.2	-0.2	-0.4	-1.9	0.2	-0.1	0.1	-0.7
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.0	0.6	1.0	0.7	0.6	0.8	-0.2	1.0	0.6	-0.6
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	0.8	-0.5	-0.9	-0.8	-0.8	0.2	-0.5	-0.9	-0.3	-0.6
Diabetes (father)	0.4	0.5	0.9	0.9	0.8	0.6	0.4	1.0	0.5	0.5	0.9	-0.3
Leg fat-free mass (left)	0.4	2.3	7.9	-0.3	-1.0	-0.8	0.3	-2.8	-2.2	-0.4	-0.1	-2.4
Townsend deprivation index at recruitment	0.4	0.6	1.1	0.8	1.0	0.9	0.7	0.9	-0.2	1.1	0.4	-0.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.8	0.6	0.7	0.7	0.5	0.5	0.9	0.6	0.4	0.6
Multivitamins +/- minerals	0.4	0.5	1.2	-1.1	-0.1	-0.9	-0.7	-0.4	-1.1	-0.6	-0.2	-0.6
Sitting height	0.4	2.8	7.3	1.6	1.2	1.3	2.7	-1.5	-0.2	2.1	2.4	0.1
Leg predicted mass (left)	0.4	2.2	7.3	-0.2	-0.9	-0.8	0.3	-2.7	-2.2	-0.3	-0.1	-2.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.2	0.8	1.0	0.9	0.8	0.3	0.2	1.1	0.8	-0.3
Had menopause	0.4	0.5	1.5	-0.8	-0.6	-0.4	-0.9	-1.2	-0.4	-0.3	-0.9	-0.4
Neuroticism score	0.4	0.9	2.0	1.4	0.5	1.1	1.2	1.0	0.5	0.9	0.5	0.7
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	5.2	-0.9	-0.4	-1.0	-0.7	-2.3	-0.7	-0.6	0.4	-2.1
Noisy workplace	0.4	0.5	0.9	-0.1	-1.0	-0.6	-0.6	0.7	-0.9	-0.6	-0.9	-0.9
Standing height	0.4	4.5	9.1	0.8	1.8	1.0	2.6	-3.0	-1.6	2.8	2.9	-0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.3	-1.0	-1.0	-0.8	-0.5	-1.1	-0.4	-0.9	-0.5	-0.7
Birth weight	0.4	1.0	2.9	0.6	1.0	0.6	1.1	0.9	-1.7	1.1	0.8	-0.4
Arm fat-free mass (right)	0.4	1.8	4.7	1.9	1.0	1.3	2.2	-0.7	-0.2	1.6	1.5	0.2
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.6	0.4	1.0	0.8	0.4	-0.3	0.4	1.0	1.3	0.1
Medication: Omeprazole	0.4	0.4	1.1	0.6	1.1	0.6	0.4	0.9	-0.1	0.9	0.3	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.9	0.2	0.2	0.4	0.5	0.6	0.9	0.3	-0.1	1.7
Leg fat-free mass (right)	0.4	2.4	6.5	-0.2	-1.2	-1.0	0.1	-2.5	-2.4	-0.6	-0.4	-2.4
Mood swings	0.4	0.7	1.1	0.7	1.0	0.9	0.8	0.6	0.8	1.0	1.0	0.3
Loneliness, isolation	0.4	0.6	0.9	0.5	0.4	0.8	0.9	-0.8	0.5	0.9	1.0	0.6
Long-standing illness, disability or infirmity	0.4	0.6	2.1	0.5	1.4	0.9	0.5	0.1	0.7	0.8	0.9	0.5
Medication: Aspirin	0.4	0.5	1.8	-1.1	0.2	-0.3	-0.8	-1.4	0.5	-0.0	0.1	-0.7
Leg predicted mass (right)	0.4	2.3	6.7	-0.2	-1.2	-0.9	0.2	-2.6	-2.4	-0.5	-0.4	-2.4
High cholesterol (Self-reported)	0.4	0.8	1.3	1.1	1.1	1.0	0.8	0.9	0.5	1.0	0.9	0.2
Medication: Paracetamol	0.4	0.6	2.0	-1.4	-0.2	-0.9	-0.5	-1.1	-0.7	-0.5	0.2	-0.8
Medication: Atorvastatin	0.4	0.5	1.3	-0.1	-0.9	-0.7	-0.2	-1.1	-0.6	-0.8	-0.2	-0.7
Arm fat-free mass (left)	0.4	1.9	4.8	1.9	1.1	1.4	2.2	-0.7	0.2	1.6	1.6	0.2
Cholesterol lowering medication	0.4	0.5	1.5	1.2	0.4	0.8	0.8	1.1	0.2	0.6	0.4	-0.4
Heart disease (siblings)	0.4	0.5	0.9	-0.5	-0.7	-0.7	-0.6	-0.6	-0.5	-0.7	-0.6	-1.0
Impedance of whole body	0.4	2.0	6.9	-2.6	-0.3	-1.4	-1.5	-2.1	-0.7	-0.4	-0.2	-1.3
Arm predicted mass (left)	0.4	1.9	4.6	1.9	1.0	1.4	2.1	-0.7	0.3	1.5	1.5	0.4
Depressed Affect (Nagel 2018)	0.3	0.5	1.0	0.8	0.5	0.8	0.6	0.5	1.0	0.6	0.7	0.9
Intelligence (Savage-Jansen 2018)	0.3	0.9	5.3	1.0	0.5	0.6	0.6	2.3	-0.4	0.6	0.3	0.4
Schizophrenia vs Biploar Disorder	0.3	0.4	0.8	-0.7	-0.5	-0.6	-0.9	0.6	-0.6	-0.5	-0.6	0.0
Worry (Nagel 2018)	0.3	0.6	2.1	0.9	0.7	0.7	0.6	1.5	0.0	0.8	0.8	0.1
Alzheimer’s Disease (in mother)	0.3	0.4	1.3	-0.2	-0.1	-0.0	-0.8	1.1	0.9	-0.1	-0.7	0.6
Alzheimer’s Disease (including proxy)	0.3	0.5	2.0	-1.4	0.1	-0.5	-1.1	-0.4	0.5	-0.2	-0.3	0.1
Allergy or Eczema	0.3	0.9	1.6	-0.9	-1.1	-1.0	-0.9	0.2	-1.0	-1.3	-0.9	-0.6
Lung FVC	0.3	1.6	6.7	-1.3	-0.5	-0.9	-1.3	-2.6	-0.1	-1.1	-0.3	-1.5
Diabetes (mother)	0.3	0.3	1.0	0.5	-0.3	0.1	-0.3	-1.0	1.0	-0.5	-0.1	-0.4
Impedance of leg (right)	0.3	1.6	3.5	-0.3	1.7	0.8	0.5	-0.1	1.9	1.4	1.7	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	1.0	0.3	0.7	0.7	0.7	-0.8	0.3	0.8	1.0	-0.3
Relative age voice broke	0.3	0.4	1.8	0.2	-0.8	0.0	0.1	1.3	-0.6	-0.6	-0.8	-0.1
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.7	0.7	0.3	0.8	0.8	0.1	0.5	0.6	0.5	0.1
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.1	-0.3	-1.0	-0.8	-0.8	0.6	-1.0	-0.7	-1.0	-0.3
Past tobacco smoking	0.3	0.5	2.2	0.4	0.2	0.4	0.5	1.5	0.6	0.2	0.4	1.0
Pain all over the body in last month	0.3	0.3	0.6	0.6	0.7	0.5	0.6	0.3	0.1	0.8	0.8	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.0	0.4	1.0	0.6	0.5	-0.4	0.5	0.9	0.8	-0.3
Number of live births	0.3	0.4	2.4	-0.4	0.0	0.1	0.1	-1.5	0.8	-0.0	0.4	-0.8
Mouth/teeth dental problems: Dentures	0.3	0.6	3.4	-1.1	0.1	-0.2	-0.3	-1.9	-0.3	0.2	-0.0	-0.6
Depression (self-reported)	0.3	0.3	1.0	0.2	1.0	0.5	0.4	0.3	-0.5	0.5	0.8	-0.4
Exposure to tobacco smoke at home	0.3	0.3	1.1	0.1	0.0	0.0	0.3	-1.1	-0.9	0.6	0.4	-0.8
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.1	-0.8	0.1	-0.2	-0.3	-1.1	0.5	-0.1	0.9	-0.2
Worry too long after embarrassment	0.3	0.5	1.2	1.1	0.1	0.5	0.8	1.1	-0.7	0.6	0.1	0.2
Neck or shoulder pain in last month	0.3	0.4	1.2	-0.7	-0.6	-0.4	-0.0	-0.6	-1.0	-0.1	0.1	-1.1
Heart disease (mother)	0.3	0.4	1.8	0.9	0.2	0.4	0.1	1.3	0.3	0.0	-0.4	0.6
Arm predicted mass (right)	0.3	1.5	4.0	1.8	0.7	1.1	2.0	-1.0	-0.1	1.3	1.3	0.4
Alcohol intake frequency.	0.3	0.8	2.6	1.4	-0.5	0.4	0.4	1.6	-0.6	0.2	-0.7	0.8
Leg pain on walking	0.3	0.3	0.8	-0.4	-0.4	-0.4	-0.9	0.5	0.2	-0.7	-0.8	-0.2
Medication: Aspirin	0.3	0.4	1.5	-1.0	0.1	-0.4	-0.7	-1.2	0.3	-0.2	-0.0	-0.6
Smoking status: Previous	0.3	0.4	2.2	-0.4	0.0	-0.3	-0.5	-1.5	-0.1	-0.2	-0.2	-0.7
Qualifications: nursing, teaching	0.3	0.5	1.6	0.7	0.5	0.6	0.5	1.3	0.7	0.5	0.4	0.5
Back pain experienced in last month	0.3	0.5	2.4	-0.6	-0.9	-0.6	-0.2	-0.1	-1.5	-0.4	-0.5	-0.4
Whole body water mass	0.3	1.5	3.8	1.6	0.8	0.9	1.9	-1.2	-0.6	1.3	1.4	-0.4
Guilty feelings	0.3	0.4	2.0	-0.2	-0.2	-0.3	0.3	-0.1	-1.1	0.3	0.1	-1.4
Financial situation satisfaction	0.3	0.4	1.8	0.6	0.4	0.7	0.3	1.4	-0.2	0.4	-0.3	0.7
Commuting to job workplace: Public transport	0.3	0.3	1.8	0.3	0.1	0.0	-0.0	1.3	-0.8	0.2	-0.1	-0.5
Ever smoked	0.3	0.5	2.2	-0.5	-0.7	-0.4	-0.4	-1.5	-0.6	-0.3	-0.5	-0.5
Average weekly beer plus cider intake	0.3	0.4	1.9	-0.2	-0.7	-0.4	-0.2	-1.4	-0.2	-0.4	0.1	-0.9
Diastolic blood pressure, automated reading	0.3	1.0	5.8	0.1	0.3	0.7	0.1	0.1	2.4	-0.0	0.6	1.4
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.2	0.5	1.1	0.4	0.2	0.8	-0.2	0.9	0.4	-0.4
Bipolar Disorder or Schizophrenia	0.2	0.5	1.4	-0.6	-1.2	-0.6	-0.6	-0.4	-0.1	-0.7	-1.0	0.0
Ovarian Cancer	0.2	0.3	0.6	-0.8	0.6	-0.6	-0.4	-0.8	-0.3	0.0	0.1	-0.3
Body Mass Index (BMI) (2010)	0.2	0.2	0.6	-0.6	0.6	-0.2	-0.1	-0.1	-0.7	0.3	0.8	-0.3
HbA1C	0.2	0.2	0.8	0.5	-0.1	0.2	0.5	0.3	-0.3	0.3	-0.2	0.9
Blood Eosinophil Count	0.2	1.6	2.9	-1.6	-0.6	-1.6	-1.1	-1.4	-1.1	-1.2	-0.5	-1.7
Smoking Status	0.2	0.5	2.0	-0.6	-0.1	-0.5	-0.5	-1.1	-0.9	-0.1	0.0	-1.4
Lung FEV1/FVC ratio	0.2	1.2	2.5	-1.1	-0.6	-1.3	-1.6	0.8	-0.9	-1.1	-0.3	-1.6
Neuroticism	0.2	0.5	0.8	0.9	0.5	0.8	0.7	0.1	0.9	0.8	0.3	0.9
Tanning	0.2	2.7	4.3	-1.6	-1.6	-1.7	-1.9	-1.4	-1.7	-1.5	-2.1	-1.0
Severe depression (siblings)	0.2	0.2	0.8	0.7	0.2	0.5	0.2	0.9	0.2	0.5	-0.2	0.6
Pack years adult smoking proportion	0.2	0.3	1.9	-0.4	0.5	-0.1	-0.1	-1.4	-0.2	0.2	0.2	-0.3
Hand grip strength (right)	0.2	0.6	1.7	1.3	-0.0	0.7	0.9	-0.1	0.8	0.0	0.4	1.1
Serious illness, injury or assault to yourself	0.2	0.2	0.5	-0.4	-0.5	-0.4	-0.2	-0.5	-0.7	-0.4	-0.6	-0.0
Impedance of leg (left)	0.2	0.8	2.9	-0.7	1.0	0.3	-0.0	-0.2	1.7	0.7	1.0	1.2
Hair/balding pattern: Pattern 2	0.2	0.3	1.4	0.9	0.1	0.4	0.0	1.2	0.4	0.1	-0.1	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	1.1	-0.5	-0.9	-0.8	-0.9	-0.2	-0.6	-0.9	-1.1	0.1
Qualifications: None of the above	0.2	0.5	2.7	-0.5	0.5	-0.4	-0.4	-1.6	-0.0	-0.2	0.6	-0.6
Mouth/teeth dental problems	0.2	0.3	1.0	-0.3	-0.3	-0.3	-0.2	-1.0	0.7	-0.7	0.3	-0.6
Time employed in main current job	0.2	0.2	0.8	0.2	0.5	0.4	0.1	0.9	0.3	0.3	0.5	0.2
Worrier / anxious feelings	0.2	0.3	1.4	0.7	-0.5	0.1	0.2	1.2	-0.6	-0.2	-0.7	-0.1
Pulse rate	0.2	0.4	0.7	-0.5	-0.6	-0.4	-0.5	0.9	-0.7	-0.8	-0.5	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.8	-0.2	-0.3	-0.2	-0.0	0.6	-0.9	-0.0	-0.3	-0.7
Qualifications: College or University degree	0.2	0.6	1.6	0.3	-0.8	-0.1	-0.3	1.3	0.3	-0.8	-1.2	0.8
Medication for pain relief, constipation, heartburn	0.2	0.3	0.9	0.7	0.2	0.5	0.4	1.0	0.5	0.2	0.4	0.8
Pulse rate, automated reading	0.2	0.6	2.0	-1.4	-0.2	-0.6	-1.4	0.2	-0.4	-0.8	-0.5	-0.3
Suffer from ‘nerves’	0.2	0.3	1.8	-0.2	-0.2	-0.4	-0.1	-0.4	-0.8	-0.2	0.3	-1.4
Whole body fat-free mass	0.2	1.3	3.3	1.4	0.7	0.8	1.8	-1.2	-0.7	1.2	1.3	-0.4
Commuting to job workplace: Walk	0.2	0.2	0.5	0.7	0.1	0.1	0.2	0.7	-0.6	0.3	0.0	-0.5
Osteoarthritis (self-reported)	0.2	0.3	1.3	-0.5	0.2	0.0	-0.0	-1.1	0.2	0.4	0.7	0.4
Medication: Gliclazide	0.2	0.2	1.2	1.1	0.1	0.4	0.4	0.8	0.1	-0.0	0.0	0.0
Ever taken oral contraceptive pill	0.2	0.3	0.6	0.5	0.3	0.4	0.7	-0.1	0.6	0.4	0.8	0.6
Basal metabolic rate	0.2	1.0	3.6	0.8	0.1	0.2	1.2	-1.9	-1.0	0.6	0.8	-1.0
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.0	-0.2	0.2	-0.0	-0.1	-0.3	-1.0	0.3	0.7	-0.6
Ever depressed for a whole week	0.2	0.3	0.8	0.7	-0.3	0.4	0.6	0.8	-0.2	0.1	-0.4	0.9
Pack years of smoking	0.2	0.3	1.8	-0.3	0.6	0.0	-0.1	-1.4	0.0	0.3	0.2	-0.0
Bipolar Disorder (2018)	0.1	0.1	0.3	0.1	-0.0	0.3	0.2	-0.1	0.6	0.4	0.2	0.0
Reaction Time	0.1	0.2	0.7	0.8	-0.3	0.3	0.7	0.6	0.5	0.1	-0.3	0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.4	-0.3	0.0	-0.4	-0.3	0.3	-0.7	-0.2	0.0	-0.4
Crohns Disease (2012)	0.1	0.1	0.4	-0.2	0.1	0.3	0.1	-0.3	0.6	0.2	0.2	0.0
Rheumatoid Arthritis	0.1	0.1	0.2	-0.5	-0.0	-0.1	-0.1	-0.5	0.3	-0.3	0.3	-0.2
Schizophrenia (2014)	0.1	0.1	0.5	-0.7	-0.2	-0.2	-0.3	-0.5	-0.2	-0.1	-0.0	0.0
Triglycerides	0.1	0.1	0.3	-0.5	-0.2	-0.3	-0.5	-0.1	0.0	-0.4	-0.4	0.2
Waist Hip Ratio (WHR)	0.1	0.6	1.3	-0.9	-0.1	-0.8	-1.1	-0.2	-1.1	-0.8	-0.6	-0.5
Number of treatments/medications taken	0.1	0.2	0.3	-0.6	-0.1	-0.3	-0.5	-0.4	-0.4	-0.4	-0.0	-0.4
Sensitivity / hurt feelings	0.1	0.2	0.5	-0.1	-0.6	-0.4	-0.2	-0.7	-0.6	-0.4	-0.4	-0.4
Hearing difficulty/problems: Yes	0.1	0.1	0.5	-0.4	0.7	-0.1	-0.1	-0.4	0.1	0.2	0.1	-0.0
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	-0.0	-0.3	0.3	0.4	-0.4	0.2	0.4	0.2	0.3
Medication for hormone replacement therapy	0.1	0.1	0.6	0.2	-0.1	0.0	0.1	0.1	-0.1	0.1	-0.0	0.8
Vitamin and mineral supplements	0.1	0.1	0.3	0.4	-0.2	0.3	0.3	-0.3	0.5	-0.0	-0.1	-0.0
Average weekly fortified wine intake	0.1	0.1	0.3	-0.6	-0.2	-0.5	-0.3	-0.2	0.4	-0.4	0.0	-0.1
Qualifications: CSEs or equivalent	0.1	0.1	0.3	0.3	0.0	0.1	0.5	-0.0	-0.0	0.3	0.5	-0.4
Supplements: Glucosamine	0.1	0.2	0.4	-0.2	0.4	-0.2	-0.1	-0.6	-0.3	0.3	0.5	-0.6
Financial difficulties in last 2 years	0.1	0.1	0.5	-0.2	0.0	-0.2	-0.5	0.5	-0.1	-0.1	-0.5	-0.7
Hair/balding pattern: Pattern 3	0.1	0.1	0.5	-0.7	0.2	-0.1	-0.1	-0.3	0.2	-0.3	0.2	-0.2
Length of working week for main job	0.1	0.1	0.4	-0.3	-0.1	-0.2	-0.3	0.6	0.2	-0.3	-0.3	0.6
Tense / ‘highly strung’	0.1	0.2	0.4	0.3	0.5	0.5	0.5	0.4	-0.5	0.6	0.4	-0.5
Medication: Paracetamol	0.1	0.1	0.5	-0.7	0.1	-0.5	-0.2	-0.3	-0.6	-0.2	0.0	-0.1
Headache pain in last month	0.1	0.2	0.6	-0.5	-0.8	-0.3	-0.3	-0.5	0.3	-0.6	-0.4	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.3	-0.5	-0.1	-0.2	-0.2	-0.5	0.1	-0.3	-0.0	-0.1
Health satisfaction	0.1	0.1	0.4	0.3	0.1	0.3	-0.2	0.6	-0.0	0.1	-0.2	0.3
Mean time to correctly identify matches	0.1	0.2	0.5	0.1	-0.6	-0.1	0.1	-0.2	-0.5	-0.1	-0.7	-0.4
Knee pain experienced in last month	0.1	0.2	0.6	0.8	-0.0	0.6	0.4	0.6	0.4	0.3	-0.1	0.2
Number of self-reported non-cancer illnesses	0.1	0.1	0.7	-0.0	0.2	0.1	-0.4	0.4	-0.1	-0.1	-0.2	0.9
Hearing aid user	0.1	0.2	0.7	0.1	0.1	-0.0	0.1	0.8	-0.7	-0.0	-0.4	0.1
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.3	0.3	0.4	0.2	0.5	-0.2	0.5	0.5	0.4	0.2
Number of operations (self-reported)	0.1	0.2	1.0	-0.0	0.0	-0.1	-0.3	0.6	-1.0	0.1	-0.1	-0.6
Pain experienced in last month	0.1	0.2	0.7	-0.1	0.8	0.2	0.1	0.4	0.3	0.5	-0.0	0.5
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.0	0.2	0.5	-0.3	0.2	-0.3	-0.6	0.2	0.7	-0.5	-0.5	0.6
Chronotype (morning person)	0.0	0.1	0.6	-0.2	0.1	-0.2	-0.4	0.8	-0.0	-0.3	0.0	-0.0
Hair Pigment	0.0	0.3	2.0	0.1	0.2	0.2	-0.0	-0.0	1.4	-0.1	0.4	0.5
Taking other prescription medications	0.0	0.1	0.2	-0.3	0.4	0.0	-0.3	0.1	-0.3	0.1	0.3	0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.4	-0.1	0.2	0.1	0.3	-0.0	-0.6	0.5	-0.1	0.3
Blood clot in the leg (DVT)	0.0	0.1	0.1	-0.1	-0.3	-0.1	-0.2	-0.4	-0.3	0.1	-0.1	0.1
Comparative body size at age 10	0.0	0.1	0.2	0.5	0.3	0.1	-0.0	-0.1	-0.3	0.2	0.0	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.1	0.1	-0.4	0.1	-0.0	-0.3	-0.0	0.1	-0.2	0.3

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LOC100133545

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