TWAS hub - C11orf1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0560	0.0210	1.1e-05	0.062	0.045	0.042	0.045	0.053	4.7e-08	3.2e-06	7.0e-06	3.3e-06	4.4e-07
2	GTEx	Artery Aorta	0.0990	0.0560	7.0e-03	0.002	NA	0.044	NA	0.031	2.5e-01	NA	1.9e-03	NA	7.9e-03
3	GTEx	Brain Cortex	0.1570	0.0710	2.3e-03	-0.008	NA	0.078	NA	0.001	6.2e-01	NA	3.5e-03	NA	2.9e-01
4	GTEx	Cells Transformed fibroblasts	0.1340	0.0510	7.1e-04	0.006	NA	0.030	NA	0.028	1.1e-01	NA	2.3e-03	NA	3.6e-03
5	GTEx	Muscle Skeletal	0.0446	0.0212	3.4e-03	0.045	NA	0.010	NA	0.021	2.8e-05	NA	3.3e-02	NA	3.5e-03
6	GTEx	Skin Not Sun Exposed Suprapubic	0.0700	0.0330	4.6e-03	0.027	NA	0.014	NA	0.034	1.3e-02	NA	5.4e-02	NA	5.8e-03
7	GTEx	Skin Sun Exposed Lower leg	0.0550	0.0280	3.0e-03	0.050	NA	0.002	NA	0.019	5.2e-05	NA	2.1e-01	NA	9.6e-03
8	ROSMAP	Brain Pre-frontal Cortex	0.0445	0.0248	2.6e-03	0.021	0.007	0.022	0.020	0.026	9.2e-04	3.3e-02	7.4e-04	1.1e-03	2.1e-04
9	TCGA	Colon Adenocarcinoma	0.1130	0.0710	1.3e-03	0.070	0.067	0.076	NA	0.068	7.3e-05	1.1e-04	3.4e-05	NA	9.3e-05
10	TCGA	Brain Lower Grade Glioma	0.0708	0.0410	1.4e-07	0.065	0.075	0.075	NA	0.074	7.7e-08	7.2e-09	6.9e-09	NA	9.2e-09
11	TCGA	Liver Hepatocellular Carcinoma	0.0860	0.0660	6.9e-03	0.014	0.026	0.017	NA	0.017	7.1e-02	2.0e-02	5.4e-02	NA	5.0e-02
12	TCGA	Prostate Adenocarcinoma	0.0384	0.0265	2.5e-03	0.027	0.023	0.021	NA	0.017	7.6e-04	1.8e-03	2.4e-03	NA	6.7e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Wheeze or whistling in the chest in last year	13.2	23.5	31.9	5.3	2.3	3.7	4.7	5.6	3.8	5.2	5.6	5.4	5.5	4.7	5.0
Allergy	10.4	24.0	31.4	-5.6	-2.9	-3.2	-4.5	-5.6	-4.2	-5.6	-5.6	-5.3	-5.6	-4.9	-4.9
Birth weight	10.1	21.9	29.3	5.4	2.5	2.3	3.8	5.2	3.8	5.3	5.3	5.4	5.2	5.0	5.4
Medication for cholesterol, blood pressure or diabetes	9.4	15.5	25.8	4.2	1.0	2.9	3.2	4.1	2.9	4.3	4.1	4.3	4.7	5.1	4.7
Asthma	9.0	17.7	23.3	4.3	2.8	3.2	4.8	4.6	2.9	4.4	4.6	4.5	4.8	4.6	4.4
Medication: Blood pressure	8.8	15.5	22.7	-4.2	-0.3	-3.6	-3.0	-4.1	-3.6	-4.3	-4.1	-4.4	-4.2	-4.5	-4.8
Hypertension (Self-reported)	8.7	24.2	36.4	-6.0	-1.2	-2.8	-4.1	-5.5	-4.9	-6.0	-5.4	-5.5	-5.3	-4.8	-5.2
Medication: Blood pressure	8.3	15.8	24.3	-4.9	-1.5	-1.9	-2.6	-4.7	-3.9	-4.9	-4.7	-4.6	-4.4	-3.6	-4.0
Cardiovascular Disease	8.2	27.0	43.2	-6.6	-2.0	-1.0	-4.4	-5.8	-4.6	-6.4	-5.8	-5.7	-6.1	-5.5	-5.2
Medication: Bendroflumethiazide	7.7	11.7	21.1	-3.9	-0.9	-1.1	-2.1	-3.8	-3.6	-3.9	-3.9	-4.2	-3.2	-3.2	-4.6
High blood pressure	7.6	21.3	31.4	-5.6	-1.1	-2.4	-4.3	-5.0	-4.8	-5.6	-5.0	-5.2	-4.9	-4.5	-4.9
Asthma (self-reported)	7.6	15.1	21.5	4.0	2.7	2.9	4.6	4.2	2.4	4.0	4.2	4.0	4.5	4.4	4.0
Allergy or Eczema	7.3	19.3	26.2	5.1	3.1	1.6	4.7	5.0	4.0	5.1	4.9	4.7	4.7	4.0	4.3
Osteoarthritis (self-reported)	7.2	9.4	15.0	3.5	1.7	-0.3	2.4	3.4	1.8	3.6	3.3	3.3	3.7	3.9	3.6
Hayfever, allergic rhinitis or eczema	7.1	15.3	20.6	4.5	2.3	2.7	3.7	4.4	4.0	4.5	4.4	4.3	4.0	3.4	4.0
Vascular/heart problems diagnosed by doctor	6.9	18.7	27.0	5.2	1.1	2.3	4.0	4.7	4.1	5.2	4.6	4.8	4.8	4.6	4.6
Systolic Blood Pressure	6.5	32.4	50.0	-7.1	-1.3	-3.1	-4.3	-6.5	-5.5	-7.0	-6.6	-6.4	-6.4	-5.5	-5.7
Respiratory disease	6.5	14.5	20.5	4.2	1.2	2.0	4.0	4.2	2.7	4.1	4.4	4.2	4.5	4.3	4.1
Ever had bowel cancer screening	6.4	7.4	11.4	-3.0	-0.2	-2.3	-3.3	-2.6	-2.6	-3.1	-2.5	-2.9	-2.5	-2.9	-3.4
Medication: Gliclazide	5.6	6.4	10.4	-2.7	1.4	-1.0	-2.1	-2.7	-2.0	-2.9	-2.9	-3.0	-2.7	-2.8	-3.2
Illnesses of father: Heart disease	5.4	7.5	11.5	-2.7	-1.9	-3.3	-3.2	-2.8	-0.9	-2.7	-2.8	-2.5	-3.4	-3.3	-2.4
Mean time to correctly identify matches	5.0	9.5	18.0	-3.2	-0.6	0.1	-1.8	-3.7	-2.7	-3.3	-3.7	-3.9	-3.3	-3.4	-4.2
Pulse rate, automated reading	4.9	15.7	22.8	4.8	-0.9	0.4	2.4	4.8	4.8	4.7	4.7	4.8	4.1	3.3	4.2
Medication: Lisinopril	4.9	6.4	9.1	-2.8	-1.4	-1.7	-1.3	-2.9	-2.0	-2.9	-2.8	-2.8	-3.0	-2.9	-2.8
Medication: Aspirin	4.6	6.0	9.6	-2.8	-0.6	-3.1	-2.5	-2.5	-1.9	-2.8	-2.6	-2.4	-2.9	-2.5	-2.0
Medication: Atenolol	4.2	5.2	7.0	-2.5	0.2	-2.2	-0.2	-2.6	-2.3	-2.5	-2.6	-2.5	-2.6	-2.7	-2.6
Medication: Ramipril	4.2	5.4	10.2	-2.6	-0.4	-1.8	-0.3	-2.6	-2.1	-2.5	-2.6	-2.8	-2.4	-2.5	-3.2
Primary Biliary Cirrhosis	4.1	5.9	8.1	-2.7	-0.9	0.1	-2.7	-2.9	-2.0	-2.6	-2.8	-2.8	-2.8	-2.5	-2.7
Medication: Co-codamol	4.0	4.6	7.2	2.6	1.3	-0.0	2.4	2.3	1.9	2.7	2.3	2.3	2.3	2.1	2.2
Systolic blood pressure, automated reading	3.9	11.5	16.3	-4.0	-1.1	-2.2	-2.4	-3.6	-3.1	-4.0	-3.7	-3.8	-3.7	-3.7	-4.0
Ulcerative Colitis (UC)	3.8	7.1	11.5	-2.8	-0.0	-2.7	-2.0	-2.9	-3.1	-3.0	-2.8	-3.2	-2.2	-2.1	-3.4
Pulse rate	3.8	6.4	9.2	3.0	1.8	1.6	1.6	3.0	2.8	2.9	3.0	2.9	2.8	2.0	2.2
Waist Hip Ratio (WHR)	3.6	16.1	95.8	-1.8	-9.8	-3.4	-2.8	-1.3	4.2	-1.2	-1.1	0.0	-4.7	-5.5	0.0
Wears glasses or contact lenses	3.6	4.1	9.8	-1.8	-0.6	-1.2	-0.8	-2.4	-0.5	-1.9	-2.4	-2.1	-3.0	-3.1	-2.2
Chronic bronchitis/emphysema (mother)	3.5	4.1	6.5	2.6	-0.1	1.3	2.3	2.4	2.4	2.6	2.3	2.2	2.0	1.1	1.6
Severe depression (siblings)	3.4	3.8	6.0	-2.4	-0.8	-1.0	-2.2	-2.4	-1.1	-2.2	-2.3	-2.2	-2.3	-1.8	-1.8
Medication: Simvastatin	3.4	5.0	9.6	-2.3	-1.8	-1.6	-2.5	-2.1	-0.9	-2.2	-2.0	-2.2	-2.6	-3.1	-2.7
Myopia	3.4	5.0	7.5	-2.4	-0.6	-2.0	-2.7	-2.4	-1.4	-2.5	-2.4	-2.2	-2.7	-2.5	-2.0
Breast Cancer	3.3	7.9	24.6	-2.9	0.8	-2.3	-3.5	-2.7	-5.0	-3.0	-2.6	-3.1	-1.4	-0.6	-2.8
Lung cancer (father)	3.3	3.8	9.3	2.4	-0.8	-0.9	1.8	2.1	3.0	2.4	2.0	2.3	1.4	0.8	1.9
Coronary Artery Disease (CAD)	3.2	3.8	6.1	-2.2	-1.8	-1.4	-2.5	-2.0	-1.4	-1.9	-2.3	-2.1	-2.3	-1.7	-1.6
Sensitivity / hurt feelings	3.2	5.5	9.2	3.0	1.1	2.0	2.3	2.7	2.0	2.8	2.8	2.4	2.9	1.9	1.5
Medication: Aspirin	3.2	4.3	7.2	-2.3	-0.9	-2.7	-1.9	-2.0	-1.6	-2.3	-2.1	-2.0	-2.3	-2.2	-1.9
Serious illness, injury or assault of a close relative in last 2 years	3.1	3.5	5.6	-1.8	-1.3	-1.3	-2.3	-2.1	-0.9	-1.9	-2.2	-2.0	-2.4	-2.1	-1.8
Reaction Time	3.0	5.8	8.4	-2.6	-0.9	1.7	-1.8	-2.8	-1.2	-2.4	-2.8	-2.7	-2.9	-2.9	-2.9
Pain type(s) experienced in last month: Hip pain	2.9	3.7	6.6	2.0	1.0	1.1	2.6	1.9	1.6	2.0	1.9	2.1	1.9	2.0	2.3
Suffer from ‘nerves’	2.8	4.4	7.9	2.8	1.0	2.5	2.6	1.9	0.6	2.4	1.9	1.4	2.8	2.5	1.0
Age at first live birth	2.6	4.6	11.2	-1.7	-1.9	-1.7	-2.3	-1.9	-0.6	-1.6	-2.0	-2.1	-2.6	-3.3	-2.7
Medication: Metformin	2.5	3.5	5.2	-2.0	1.2	-1.4	-1.2	-2.2	-2.1	-2.3	-2.2	-2.2	-1.7	-1.3	-2.1
Multivitamins +/- minerals	2.5	3.1	4.6	2.1	0.2	0.6	2.1	2.0	2.0	2.0	2.0	2.0	1.6	1.3	1.9
Financial difficulties in last 2 years	2.5	3.4	6.0	1.9	0.4	1.6	1.0	2.0	2.1	2.0	2.1	2.3	1.7	1.7	2.5
Birth weight of first child	2.5	4.4	7.4	2.3	1.0	2.5	2.7	2.2	0.8	2.4	2.2	1.9	2.7	2.2	1.4
Unable to work because of sickness or disability	2.5	3.2	5.4	1.8	-0.5	1.5	0.1	2.1	2.3	1.9	2.2	2.3	1.6	1.4	2.2
Medication for cholesterol	2.4	3.7	6.5	2.5	0.7	1.0	1.1	2.0	1.8	2.4	2.1	2.2	1.9	2.0	2.3
Lupus	2.3	3.5	8.2	-1.9	-0.4	-1.8	-1.6	-2.1	-2.9	-1.9	-2.0	-2.3	-1.4	-1.0	-2.1
High cholesterol (Self-reported)	2.3	4.1	7.2	-2.4	-1.6	-1.2	-1.7	-2.1	-0.7	-2.4	-2.1	-1.9	-2.6	-2.7	-1.9
Mouth/teeth dental problems: Loose teeth	2.2	2.6	3.9	1.8	0.0	1.4	1.4	2.0	2.0	1.6	1.9	1.9	1.4	0.9	1.7
Emphysema/chronic bronchitis	2.2	2.5	4.4	1.4	1.0	1.1	-0.1	2.1	1.4	1.4	2.1	2.1	1.8	1.4	2.0
Ever used hormone-replacement therapy (HRT)	2.1	2.7	7.0	1.6	1.1	0.7	1.6	1.5	0.5	1.6	1.5	1.6	2.2	2.6	1.9
Maternal smoking around birth	2.1	3.1	7.3	1.6	-0.7	-1.2	0.8	2.1	1.8	1.8	2.1	2.3	1.4	1.4	2.7
Number of full brothers	2.1	2.6	5.2	2.0	0.8	1.1	-0.0	1.6	0.8	1.9	1.6	1.7	1.9	2.3	2.1
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.4	8.4	2.1	-0.6	0.5	-0.0	2.5	2.9	2.2	2.5	2.7	1.8	1.6	2.8
Bipolar Disorder (2018)	2.0	3.2	7.9	-1.6	-1.8	-0.0	-1.9	-1.8	-0.6	-1.6	0.0	-1.8	-2.3	-2.8	-2.3
Medication: Cholesterol lowering	2.0	3.1	5.7	-1.7	-1.0	-1.1	-1.7	-1.8	-1.0	-1.8	-1.8	-1.8	-2.2	-2.4	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.0	4.1	2.0	0.4	1.6	1.6	1.8	1.3	2.0	1.9	1.9	1.9	1.9	2.0
Ever highly irritable/argumentative for 2 days	2.0	2.4	5.8	1.8	0.5	-0.0	1.1	1.6	0.2	1.6	1.7	1.6	2.1	2.4	2.0
Medication: Ventolin 100micrograms inhaler	2.0	2.5	5.2	1.8	0.7	2.3	1.6	1.5	0.4	1.5	1.5	1.3	2.0	2.0	1.3
Shortness of breath walking on level ground	2.0	2.4	7.5	1.4	2.2	1.1	0.8	1.2	-0.4	1.1	1.2	1.1	2.2	2.7	1.4
Qualifications: College or University degree	2.0	6.2	13.2	-2.8	-1.7	-1.8	-2.9	-2.2	-0.9	-2.4	-2.3	-2.3	-3.0	-3.6	-2.8
Diabetes diagnosed by doctor	2.0	3.3	6.6	-1.9	1.1	-0.5	-1.4	-1.8	-2.2	-2.1	-1.8	-2.2	-1.5	-1.7	-2.6
Fractured/broken bones in last 5 years	2.0	2.6	7.9	1.8	-2.3	-0.2	1.4	1.4	2.8	1.9	1.4	1.7	0.6	0.3	1.5
Diastolic blood pressure, automated reading	2.0	6.3	10.2	-3.2	-1.2	-0.8	-2.7	-2.6	-2.6	-3.1	-2.6	-2.8	-2.4	-2.4	-2.8
High blood pressure (mother)	1.9	2.7	5.8	-1.9	-0.6	1.3	-2.4	-1.5	-1.8	-1.9	-1.4	-1.7	-1.2	-1.2	-1.8
Illnesses of father: None of the above (group 1)	1.9	2.3	4.6	1.6	2.1	1.0	0.9	1.7	0.5	1.6	1.7	1.4	2.0	1.8	1.2
Ever taken oral contraceptive pill	1.9	2.1	5.2	1.1	-0.1	2.3	0.9	1.3	0.9	1.2	1.4	1.4	1.8	2.0	1.5
Qualifications: CSEs or equivalent	1.8	2.4	7.5	1.3	1.4	1.6	1.5	1.1	-0.0	1.4	1.1	1.1	2.0	2.7	1.7
Medication: Amlodipine	1.8	2.5	4.4	-1.7	0.7	-1.9	-2.1	-1.8	-2.0	-1.9	-1.7	-1.6	-1.4	-0.3	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	8.3	1.4	-1.4	-0.4	-0.1	1.5	2.9	1.4	1.4	1.6	0.4	-0.3	1.2
Financial situation satisfaction	1.8	2.3	3.9	1.7	0.2	0.2	0.1	2.0	1.3	1.6	2.0	2.0	1.8	1.4	1.7
Ever had prostate specific antigen (PSA) test	1.8	2.1	3.8	-1.6	-0.5	-1.0	-1.9	-1.5	-0.5	-1.4	-1.4	-1.4	-1.8	-1.9	-1.5
Bipolar Disorder (2011)	1.7	1.6	5.2	-2.0	0.2	0.0	-1.5	-1.9	-2.0	-2.3	0.0	0.0	0.0	0.0	0.0
Fed-up feelings	1.7	3.0	8.0	1.6	1.7	0.2	2.6	1.4	0.2	1.5	1.4	1.3	2.3	2.8	1.6
Chronic bronchitis/emphysema (father)	1.7	2.0	3.8	1.3	-0.1	0.3	1.0	1.7	1.8	1.4	1.6	1.9	1.2	1.1	2.0
Hayfever/allergic rhinitis (self-reported)	1.7	2.2	3.5	1.9	-0.2	0.1	1.2	1.5	1.9	1.8	1.6	1.7	1.4	1.5	1.8
Average weekly red wine intake	1.7	2.5	4.8	-1.5	-0.1	-1.4	0.0	-2.0	-1.3	-1.4	-1.9	-2.0	-1.6	-1.6	-2.2
Mouth/teeth dental problems	1.6	2.4	6.8	-1.5	-0.3	0.0	-2.2	-1.5	0.2	-1.3	-1.4	-1.2	-2.2	-2.6	-1.5
Pulse wave peak to peak time	1.6	1.9	3.1	1.4	0.7	-0.9	1.7	1.4	0.8	1.4	1.4	1.4	1.6	1.8	1.6
Heart disease (mother)	1.6	1.9	5.2	-1.6	0.1	-0.7	-1.7	-1.3	-2.3	-1.6	-1.4	-1.7	-0.6	-0.3	-1.6
Illnesses of father: High blood pressure	1.6	2.0	3.4	-1.6	-0.4	-0.0	0.4	-1.7	-1.6	-1.5	-1.7	-1.8	-1.5	-1.5	-1.8
Ulcerative Colitis	1.5	2.1	5.2	-1.4	0.3	-2.1	-0.4	-1.3	-1.0	-1.6	0.0	-1.6	-1.3	-2.1	-2.3
Blood Eosinophil Count	1.5	11.2	16.1	-4.0	-2.7	-1.9	-2.5	-3.6	-3.9	-3.6	-3.5	-3.9	-3.0	-2.8	-4.0
Sitting height	1.5	10.5	15.2	3.4	0.9	3.0	1.4	3.9	2.8	3.6	3.9	3.8	3.7	3.3	3.6
Had other major operations	1.5	1.8	3.9	1.3	-0.1	2.0	-0.8	1.4	1.2	1.3	1.6	1.4	1.6	1.4	1.3
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	2.7	1.5	0.3	1.1	1.3	1.5	1.2	1.4	1.5	1.5	1.6	1.4	1.2
Mouth/teeth dental problems: Dentures	1.5	2.5	5.0	1.8	-0.1	-0.3	2.2	1.9	1.1	1.5	1.8	1.7	1.7	1.6	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	4.5	1.0	-0.4	1.6	0.3	1.7	1.7	1.1	1.7	1.9	1.1	1.0	2.1
Health satisfaction	1.5	1.9	3.6	1.5	-1.7	-0.2	0.7	1.4	1.9	1.4	1.5	1.6	1.1	0.8	1.5
Back pain experienced in last month	1.5	2.2	6.1	1.1	0.2	1.8	0.6	1.3	0.1	1.1	1.4	1.5	1.7	2.5	2.4
Pain experienced in last month	1.5	2.4	9.1	-1.5	0.5	-1.4	-0.7	-1.2	0.1	-1.3	-1.2	-1.4	-2.0	-3.0	-2.2
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	4.3	0.8	1.8	-2.1	1.2	1.0	-0.6	0.8	1.0	0.6	1.6	1.4	0.5
Pulse wave Arterial Stiffness index	1.4	1.6	2.9	-1.2	-0.6	1.1	-1.7	-1.2	-0.7	-1.2	-1.2	-1.2	-1.4	-1.6	-1.5
Pulse wave reflection index	1.4	1.8	3.6	-1.3	-1.6	1.1	-1.2	-1.2	-0.7	-1.0	-1.2	-1.3	-1.5	-1.9	-1.6
Prostate Cancer	1.3	1.8	4.8	-1.7	0.1	-0.3	-0.9	-1.5	-2.2	-1.9	-1.5	-1.5	-1.1	-0.6	-1.1
Serious illness, injury or assault to yourself	1.3	1.5	2.9	0.8	-1.7	1.4	0.4	1.2	1.2	1.1	1.2	1.3	1.1	1.3	1.5
Eye problems/disorders: None of the above	1.3	1.5	2.1	1.1	-1.0	1.5	-0.3	1.4	1.2	1.4	1.4	1.4	1.3	1.2	1.3
Neck or shoulder pain in last month	1.3	1.8	3.1	1.5	-0.1	0.2	1.8	1.3	1.0	1.6	1.3	1.4	1.5	1.7	1.5
Tinnitus: Yes, now most or all of the time	1.3	1.5	3.8	1.2	-0.7	1.9	0.9	1.3	1.6	1.4	1.2	1.4	0.8	0.4	1.1
Triglycerides	1.2	1.9	3.0	0.9	-0.8	-1.6	-1.5	0.9	1.0	1.2	1.7	1.7	1.5	1.4	1.7
Townsend deprivation index at recruitment	1.2	1.6	4.3	0.7	1.7	1.6	0.3	1.0	0.3	0.6	0.9	1.2	1.3	2.1	2.0
Supplements: Glucosamine	1.2	1.6	4.5	1.2	-0.3	1.2	1.4	1.2	2.1	1.3	1.2	1.5	0.6	0.5	1.6
Alcohol usually taken with meals	1.2	1.9	3.6	-1.6	-0.6	-1.0	-0.2	-1.6	-0.4	-1.3	-1.6	-1.5	-1.8	-1.9	-1.6
Number of children fathered	1.2	1.3	2.3	1.2	-0.6	-0.4	1.4	1.1	1.4	1.5	1.1	1.3	0.7	0.8	1.5
Chest pain or discomfort	1.2	1.7	6.0	1.0	1.9	2.2	2.4	0.6	0.2	0.9	0.7	0.6	1.2	1.3	0.6
Alcohol drinker status: Never	1.2	1.4	4.4	1.1	0.2	2.1	1.8	0.9	1.4	1.1	1.0	1.1	0.7	0.5	1.0
Blood Platelet Count	1.1	12.6	36.5	3.9	1.6	1.7	6.0	3.3	3.2	4.0	3.3	3.4	3.6	3.5	3.2
Ever had hysterectomy (womb removed)	1.1	1.2	3.9	1.0	1.1	0.2	1.1	0.9	-0.3	0.8	0.9	0.9	1.4	2.0	1.4
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	3.3	1.2	0.7	1.8	1.2	1.0	0.6	0.9	0.9	1.0	1.1	1.3	1.2
Exposure to tobacco smoke at home	1.1	1.2	5.4	0.6	1.3	0.6	1.2	0.5	-0.7	0.7	0.6	0.6	1.3	2.3	1.4
Medication: Ibuprofen	1.1	1.4	2.3	1.2	0.2	1.2	1.2	1.3	0.5	1.0	1.2	1.2	1.5	1.5	1.2
Comparative height size at age 10	1.1	6.1	9.4	3.0	0.1	0.2	1.5	3.1	2.2	2.8	3.0	3.1	2.6	2.3	3.0
Smoking status: Previous	1.1	1.6	4.9	-1.4	0.3	0.3	-0.7	-1.6	-2.2	-1.7	-1.5	-1.4	-1.1	0.1	-0.4
Hypothyroidism (self reported)	1.0	2.2	6.7	-1.4	2.4	1.3	-0.2	-1.3	-2.6	-1.5	-1.4	-1.6	-0.4	0.2	-1.4
Alcohol intake versus 10 years previously	1.0	1.5	2.5	1.3	1.1	0.3	1.3	1.6	0.3	1.2	1.5	1.3	1.6	1.4	1.3
Number of live births	1.0	1.3	5.5	1.1	0.9	0.6	0.0	0.8	-1.1	0.5	1.0	0.8	1.7	2.3	1.3
Headache pain in last month	1.0	1.7	4.7	1.4	0.4	1.0	0.5	1.1	0.6	1.2	1.2	1.3	1.6	2.2	1.7
Glaucoma (self-reported)	1.0	1.2	1.7	-1.1	1.0	-0.7	-1.0	-1.2	-1.3	-1.2	-1.2	-1.3	-1.0	-0.9	-1.3
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	7.6	-1.2	2.8	0.3	-0.2	-1.2	-2.5	-1.3	-1.1	-1.5	-0.3	-0.2	-1.6
High blood pressure (siblings)	1.0	1.4	2.7	-1.4	-1.5	1.2	-0.9	-1.0	-1.1	-1.1	-0.9	-1.1	-0.8	-1.3	-1.6
Age at last live birth	1.0	1.5	3.3	-0.6	-0.4	-1.6	-1.1	-1.1	-1.3	-0.7	-1.1	-1.5	-1.0	-1.4	-1.8
Schizophrenia vs Biploar Disorder	0.9	1.1	2.8	1.0	1.5	-0.6	1.3	1.2	0.2	1.2	0.0	0.9	1.7	1.3	0.4
Ovarian Cancer	0.9	1.3	2.6	-1.0	0.1	-0.9	-1.3	-1.3	-0.9	-1.0	-1.3	-1.5	-0.9	-0.9	-1.6
Neuroticism (2016)	0.9	1.4	4.5	1.3	-0.4	2.1	0.9	1.1	0.3	1.1	1.1	1.0	1.4	1.3	0.9
Lung FVC	0.9	4.7	7.1	-2.7	-0.3	-1.5	-2.6	-2.4	-1.9	-2.5	-2.4	-2.3	-2.3	-1.9	-2.0
Number of treatments/medications taken	0.9	1.6	3.7	-1.6	-0.2	-1.0	-1.9	-1.1	-1.7	-1.7	-1.0	-1.2	-1.0	-0.8	-1.0
Diabetes (self-reported)	0.9	1.4	3.0	-1.2	1.2	-0.5	-0.7	-1.1	-1.7	-1.4	-1.1	-1.4	-0.7	-0.8	-1.7
Happiness	0.9	1.0	4.7	-0.9	-0.0	0.1	-2.2	-1.3	-0.4	-1.0	-1.3	-1.0	-1.1	-0.3	-0.4
Prospective memory result	0.9	1.1	2.8	1.1	0.3	1.7	0.4	1.0	-0.1	0.7	1.1	1.0	1.2	1.5	1.3
Breastfed as a baby	0.9	1.1	3.3	-1.3	-1.8	-0.0	-1.0	-1.0	-0.8	-1.0	-0.9	-0.8	-1.2	-1.0	-0.6
Overall health rating	0.9	2.0	4.1	1.4	1.5	1.0	1.4	1.4	0.6	1.2	1.3	1.4	1.7	2.0	1.7
Leg pain on walking	0.9	1.1	7.3	-0.0	-1.1	1.2	-2.7	0.2	1.0	-0.1	0.3	0.7	-0.4	-0.1	1.1
Knee pain experienced in last month	0.9	1.4	3.8	1.2	1.4	0.3	0.2	1.0	0.2	1.0	1.0	1.3	1.3	1.9	1.9
Illnesses of siblings: Diabetes	0.9	1.1	5.4	0.7	1.8	2.3	-0.5	0.6	0.1	0.5	0.7	0.6	1.0	1.1	0.7
Basal cell carcinoma (self-reported)	0.9	1.1	2.6	-1.3	-0.3	-1.1	-1.1	-1.2	-0.3	-1.1	-1.1	-0.8	-1.6	-1.2	-0.3
Bipolar Disorder or Schizophrenia	0.8	1.9	3.0	-1.7	-0.3	-0.3	-1.5	-1.6	-1.3	-1.6	0.0	-1.6	-1.5	-1.5	-1.7
Depression (Nagel 2018)	0.8	1.2	5.6	-1.2	0.0	2.4	-1.1	-1.0	-1.0	-1.1	-0.9	-1.0	-0.5	0.1	-0.6
Alzheimer’s Disease (including proxy)	0.8	1.2	5.1	0.7	-1.9	1.0	-0.8	0.5	2.3	1.0	0.5	0.9	-0.3	-0.7	0.6
Irritable Bowel Disease (IBD)	0.8	1.8	4.9	-1.1	1.2	-1.5	-0.3	-1.2	-1.7	-1.2	-1.2	-1.6	-0.7	-1.2	-2.2
Height	0.8	15.9	27.9	4.4	0.6	1.9	1.1	5.0	4.9	4.3	5.0	5.3	3.8	2.9	5.0
Vitamin and mineral supplements	0.8	1.1	1.8	-1.2	0.6	0.0	-1.0	-1.2	-1.3	-1.3	-1.2	-1.2	-0.8	-0.6	-1.2
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.3	0.9	0.2	1.1	1.3	1.0	-0.2	0.7	0.9	0.8	1.5	1.5	0.7
Medication: Seretide 50 evohaler	0.8	0.9	3.3	0.1	1.6	1.0	0.8	0.4	-1.1	0.1	0.5	0.3	1.2	1.8	0.8
Commuting to job workplace: Public transport	0.8	0.9	1.6	1.2	-0.5	-0.5	0.3	1.0	0.7	1.1	1.0	1.1	1.1	1.3	1.3
Ever depressed for a whole week	0.8	0.9	1.6	1.2	-0.2	0.3	0.8	1.3	0.9	1.1	1.2	1.2	1.2	0.9	0.9
Alzheimer’s Disease (in father)	0.7	0.8	3.7	0.4	-1.4	1.9	0.5	0.7	1.2	0.5	0.7	0.8	0.4	0.1	0.6
Mean Putamen Volume	0.7	0.8	1.5	0.9	-0.1	-0.1	0.7	1.0	0.3	0.9	1.1	1.0	1.1	1.2	1.2
HbA1C	0.7	0.7	3.6	-0.6	-0.0	-0.5	-0.2	-0.4	-0.8	-0.5	-0.8	-1.2	-0.5	-1.1	-1.9
Type 2 Diabetes (T2D) (2018)	0.7	1.2	2.8	-1.2	1.2	0.5	-0.6	-1.0	-1.1	-1.3	-1.1	-1.3	-0.8	-1.0	-1.7
Hand grip strength (left)	0.7	1.9	4.7	1.6	-1.0	1.0	0.8	1.5	2.2	1.7	1.6	1.6	1.0	0.4	1.1
Frequency of depressed mood in last 2 weeks	0.7	0.9	4.0	-1.1	-0.3	2.0	-1.1	-1.0	-0.8	-1.1	-0.9	-0.8	-0.6	0.2	-0.1
Blood clot in the leg (DVT)	0.7	0.9	1.7	1.1	-1.0	-0.1	0.4	0.9	0.2	1.2	1.0	0.8	1.3	1.3	0.7
Hearing aid user	0.7	0.8	5.1	-0.6	-0.4	-2.3	-1.0	-0.7	-0.7	-0.7	-0.6	-0.5	-0.6	-0.3	-0.2
Risk taking	0.7	1.0	5.7	-0.5	-2.4	-1.1	-1.2	0.3	1.0	-0.1	0.3	0.5	-0.6	-0.9	0.5
Crohns Disease (2017)	0.6	1.3	4.0	1.2	2.0	0.4	1.5	1.2	0.5	1.2	1.2	1.0	1.3	0.8	0.6
Age at First Birth	0.6	0.9	3.4	-0.5	-1.4	-0.3	-1.1	-0.3	0.5	-0.3	-0.3	-0.5	-0.8	-1.8	-1.5
HDL Cholesterol	0.6	1.1	5.3	0.2	1.8	1.0	2.3	-0.0	-1.1	-0.1	0.1	-0.1	1.0	1.0	-0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.4	-0.8	0.7	-0.0	-0.6	-0.7	-0.6	-0.8	-1.2	-1.1	-1.0	-0.7	-0.9
Stomach or abdominal pain in last month	0.6	0.7	3.8	0.5	0.9	2.0	0.8	0.5	0.2	0.4	0.5	0.6	0.5	0.9	1.1
Past tobacco smoking	0.6	1.1	4.4	1.2	0.1	-0.0	0.1	1.2	2.1	1.4	1.1	0.9	0.6	-1.0	-0.5
Nervous feelings	0.6	1.0	4.2	1.0	2.1	0.5	1.2	0.6	0.1	0.8	0.6	0.5	1.1	1.5	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	4.5	0.6	1.7	2.1	0.5	0.0	-0.3	0.5	0.2	0.2	0.8	1.6	0.8
Neuroticism score	0.6	1.4	5.3	1.4	-0.1	0.6	0.9	0.8	-0.0	1.2	0.9	0.8	1.7	2.3	1.2
Hip circumference	0.6	2.7	5.0	1.8	0.8	1.4	1.1	1.9	0.7	1.6	1.9	1.7	2.2	2.1	1.5
Hair/balding pattern: Pattern 3	0.6	1.0	3.4	-0.7	-1.3	-1.8	1.1	-0.9	-0.5	-0.6	-0.8	-0.8	-0.9	-0.9	-0.8
Standing height	0.6	5.9	10.4	2.4	-0.4	2.2	0.7	2.9	3.2	2.5	2.9	3.2	2.0	1.6	3.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.1	1.3	-0.3	-0.8	0.5	0.5	0.1	1.0	0.7	0.6	1.1	1.4	0.9
Commuting to job workplace: Walk	0.6	0.6	1.2	-1.1	-0.8	-0.2	-0.7	-0.6	-0.8	-1.1	-0.5	-0.7	-0.8	-1.0	-0.8
Smoking status: Current	0.6	0.9	2.4	0.7	0.1	0.5	0.5	1.0	0.6	0.8	1.0	1.1	1.2	1.6	1.4
Number of operations (self-reported)	0.6	1.0	3.0	0.9	0.4	1.5	0.1	0.9	1.7	1.0	1.0	1.1	0.5	0.2	0.9
Age started oral contraceptive pill	0.6	0.7	5.4	-0.1	0.1	-2.3	-0.3	-0.2	-0.0	-0.2	-0.3	-0.5	-0.3	-0.9	-1.3
Supplements: Calcium	0.6	0.7	2.9	0.8	0.2	0.1	-0.5	1.1	1.7	0.9	1.1	1.0	0.5	-0.6	0.1
Alzheimer’s Disease (in mother)	0.5	0.6	2.1	0.3	-1.4	-1.1	-1.0	0.1	1.3	0.4	0.1	0.4	-0.4	-0.5	0.4
Body Mass Index (BMI) (2010)	0.5	0.7	2.9	0.5	-0.3	1.7	-0.1	0.7	0.2	0.5	1.0	1.0	1.0	0.8	0.9
LDL Cholesterol	0.5	0.8	4.4	-0.0	-1.3	-1.5	-2.1	0.4	0.3	-0.0	0.4	0.4	0.4	0.3	0.3
Medication for hormone replacement therapy	0.5	0.5	1.5	0.7	0.4	0.2	0.2	0.7	0.4	0.8	0.7	0.8	1.0	1.2	1.0
Relative age voice broke	0.5	0.8	2.5	1.1	-0.1	0.5	0.8	1.1	1.6	1.0	1.1	1.0	0.5	-0.1	0.6
Waist circumference	0.5	1.9	15.6	0.1	-3.9	-0.7	-0.6	0.5	1.6	0.1	0.6	0.9	-0.6	-0.9	0.8
Qualifications: None of the above	0.5	1.2	2.9	1.3	-0.1	-1.1	1.2	0.8	0.1	0.8	0.8	1.0	1.1	1.7	1.6
Heart attack	0.5	0.6	2.4	0.8	1.6	-1.2	0.9	0.4	0.6	0.6	0.4	0.5	0.4	0.3	0.4
Illnesses of siblings	0.5	0.6	2.0	0.9	-0.3	-1.4	0.9	0.6	1.2	0.8	0.5	0.7	0.3	0.3	0.7
Trunk fat-free mass	0.5	2.9	5.5	1.8	-0.0	0.8	0.1	2.2	1.4	1.7	2.2	2.3	1.8	1.7	2.4
Illnesses of mother	0.5	0.6	2.1	0.4	-0.6	-1.1	0.7	0.3	1.2	0.7	0.3	0.7	-0.2	0.3	1.4
Trunk predicted mass	0.5	3.0	5.6	1.8	0.0	0.8	0.1	2.2	1.5	1.7	2.2	2.3	1.8	1.7	2.4
Loud music exposure frequency	0.5	0.5	2.8	0.5	-1.7	-0.4	0.2	0.3	1.0	0.4	0.3	0.6	-0.2	0.0	0.9
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.8	0.8	0.1	0.9	0.7	0.8	-0.2	1.0	0.8	0.6	1.4	1.3	0.4
Forced vital capacity (FVC), Best measure	0.5	2.0	3.8	1.3	0.5	1.5	0.2	1.5	1.9	1.5	1.5	1.7	1.3	1.2	1.7
Worry too long after embarrassment	0.5	0.8	5.6	-0.1	-1.2	2.4	-0.9	-0.5	-0.4	-0.5	-0.5	-0.5	-0.3	0.1	-0.2
Angina (self-reported)	0.5	0.7	2.9	0.4	1.7	-1.3	1.0	0.4	0.2	0.3	0.4	0.6	0.3	0.6	1.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	2.4	1.0	1.6	-0.8	0.7	1.0	0.7	0.6	0.9	0.7	0.4	-0.3	0.3
Breast cancer (self-reported)	0.5	0.6	2.3	-0.2	-1.3	1.1	-0.9	0.1	0.5	-0.2	0.1	-0.2	-0.6	-1.5	-0.9
Basal metabolic rate	0.5	2.5	4.8	1.7	-0.2	0.6	0.1	2.0	1.2	1.5	2.0	2.1	1.8	1.7	2.2
Commuting to job workplace: Cycle	0.5	0.6	3.6	-0.5	-0.3	-1.9	-1.5	-0.1	0.1	-0.4	-0.2	-0.1	-0.7	-0.8	-0.1
Heart disease (siblings)	0.5	0.6	1.4	-1.1	0.9	-0.2	-0.8	-0.7	-1.2	-1.0	-0.7	-0.7	-0.3	0.2	-0.4
Arm predicted mass (left)	0.5	2.7	5.8	1.7	-0.5	0.7	-0.3	2.1	1.5	1.5	2.1	2.2	1.6	1.6	2.4
Intelligence (Savage-Jansen 2018)	0.4	1.3	2.4	0.9	-0.1	0.1	1.3	1.3	1.0	1.3	1.5	1.3	1.6	1.1	0.8
Worry (Nagel 2018)	0.4	0.8	2.7	0.9	1.3	1.5	1.6	0.3	-0.0	0.6	0.4	0.1	0.9	0.8	-0.1
Fasting Glucose	0.4	0.4	1.3	1.0	0.0	0.1	1.1	0.8	0.7	1.1	0.3	0.2	0.5	0.4	0.1
Blood Red Count	0.4	3.6	12.6	1.0	-3.3	-0.1	-1.4	1.8	3.5	1.1	1.7	2.1	-0.2	-1.4	1.6
Smoking Status	0.4	0.8	3.1	-0.9	0.1	1.1	0.3	-0.7	-1.8	-1.0	-0.7	-0.6	0.1	1.5	0.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	3.4	-0.6	0.6	0.7	-1.9	-0.1	0.4	-0.4	-0.2	-0.1	-0.5	-0.6	-0.1
Angina	0.4	0.5	2.0	0.2	1.4	-1.4	1.0	0.2	0.1	0.1	0.3	0.5	0.1	0.3	0.8
Supplements: Zinc	0.4	0.4	3.3	0.0	0.8	1.8	-0.8	-0.1	-0.1	0.1	0.1	0.1	0.3	0.7	0.3
Impedance of leg (right)	0.4	1.8	7.4	1.3	-0.4	1.3	1.6	1.1	2.7	1.5	1.1	1.4	0.6	0.2	1.1
Current tobacco smoking	0.4	0.7	1.8	0.5	-0.0	0.6	0.4	0.9	0.7	0.6	0.8	1.0	1.0	1.3	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.0	-0.1	1.1	1.4	0.3	0.1	-0.3	0.1	0.1	0.2	0.8	1.4	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	6.0	-0.0	-2.4	0.5	-1.7	0.0	-0.7	-0.0	0.3	0.0	0.1	0.3	0.4
Medication: Levothyroxine sodium	0.4	0.7	4.3	-0.6	2.1	0.2	-0.8	-0.3	-1.3	-0.6	-0.3	-0.5	0.0	0.1	-0.6
Leg predicted mass (left)	0.4	1.9	4.0	1.5	0.1	0.4	0.1	1.7	0.5	1.2	1.7	1.7	1.7	1.9	2.0
Worrier / anxious feelings	0.4	0.8	2.1	-0.1	1.5	1.3	1.1	-0.8	-1.2	-0.4	-0.8	-1.0	0.0	0.2	-1.1
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.8	-0.4	-1.4	0.3	1.2	-0.2	1.2	-0.2	-0.3	-0.2	-0.9	-1.7	-0.9
Length of working week for main job	0.4	0.4	1.0	-0.7	1.0	-0.2	-0.3	-0.7	-0.7	-0.7	-0.7	-0.7	-0.6	-0.3	-0.4
Commuting to job workplace: Car/motor vehicle	0.4	0.4	3.4	0.3	-0.5	1.8	0.9	0.1	0.6	0.5	0.1	0.2	0.2	-0.1	-0.2
Whole body fat-free mass	0.4	2.5	4.9	1.6	0.0	0.7	-0.0	2.0	1.1	1.5	2.0	2.1	1.8	1.7	2.2
Long-standing illness, disability or infirmity	0.4	0.5	3.0	0.3	1.7	-0.1	0.1	0.7	-0.4	0.4	0.7	0.5	0.9	0.9	0.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	3.3	-0.2	-1.0	-1.0	-0.4	-0.6	-1.8	-0.7	-0.4	-0.7	0.2	0.6	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.0	-0.5	-1.1	0.4	-0.7	-0.3	0.5	-0.5	-0.3	-0.3	-0.8	-1.4	-0.7
Whole body water mass	0.4	2.3	4.6	1.6	-0.0	0.7	-0.0	2.0	1.1	1.4	2.0	2.0	1.7	1.6	2.1
Miserableness	0.4	0.8	3.8	0.3	0.3	1.1	0.3	0.1	-1.4	0.3	0.2	-0.0	1.4	1.9	0.2
Ever smoked	0.4	0.8	2.9	-0.5	0.7	0.4	0.7	-0.4	-1.6	-0.7	-0.4	-0.1	0.2	1.7	1.3
Arm fat-free mass (left)	0.4	1.8	4.1	1.4	-0.6	0.5	-0.1	1.7	1.2	1.2	1.7	1.8	1.3	1.3	2.0
Average weekly beer plus cider intake	0.4	0.6	1.3	0.5	0.0	1.0	-0.5	0.9	1.0	0.7	0.9	1.1	0.4	0.2	1.1
Pack years of smoking	0.4	0.7	5.3	-0.5	-0.4	-2.3	-0.2	-0.5	-0.2	-0.7	-0.5	-0.4	-0.7	-0.5	-0.3
Rheumatoid Arthritis	0.3	0.4	2.2	0.4	1.3	0.4	1.5	-0.1	0.5	0.2	-0.1	-0.1	-0.2	-0.4	-0.2
Heel T-Score	0.3	2.4	15.8	0.3	-4.0	0.2	-2.8	-0.1	-1.8	0.1	0.3	-0.1	0.5	1.1	0.6
Neuroticism	0.3	0.7	3.1	-0.4	-0.3	0.1	0.3	-1.0	-1.8	-0.8	-0.8	-1.0	0.1	0.8	-0.6
Hair Pigment	0.3	9.1	20.4	-3.4	-0.4	-1.9	-2.9	-3.3	-4.5	-3.6	-3.3	-3.6	-2.0	-1.2	-3.3
Hearing difficulty/problems: Yes	0.3	0.5	2.7	0.7	-0.4	0.2	1.6	0.5	0.5	0.8	0.5	0.6	0.5	0.4	0.5
Relative age of first facial hair	0.3	0.7	2.3	-0.1	-0.9	0.6	-1.3	0.0	1.4	0.0	0.1	0.0	-0.7	-1.5	-0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.8	-0.2	-0.3	-1.3	-1.1	-0.3	-0.4	-0.5	-0.3	-0.2	-0.2	-0.1	-0.2
Diabetes (father)	0.3	0.4	2.2	-0.0	0.5	-0.8	1.5	-0.3	-0.9	-0.0	-0.3	-0.6	0.1	0.1	-0.7
Diabetes (mother)	0.3	0.4	1.0	-0.4	-0.0	1.0	-1.0	-0.8	-0.7	-0.7	-0.7	-0.5	-0.6	0.1	0.1
Leg fat-free mass (left)	0.3	1.8	3.8	1.4	0.1	0.5	0.1	1.6	0.3	1.2	1.6	1.6	1.7	1.9	1.9
Hand grip strength (right)	0.3	0.7	2.0	1.0	-0.7	0.6	0.5	1.0	1.4	1.1	1.0	0.9	0.6	-0.0	0.4
Impedance of leg (left)	0.3	1.3	7.0	0.8	-0.3	1.4	1.2	0.7	2.6	1.1	0.8	1.0	-0.0	-0.6	0.6
Hair/balding pattern: Pattern 2	0.3	0.3	1.8	0.1	-0.3	1.4	0.6	0.2	0.9	0.3	0.1	0.3	0.2	0.6	0.6
Forced vital capacity (FVC)	0.3	1.3	2.9	1.2	0.6	1.0	0.3	1.2	1.7	1.3	1.2	1.4	0.9	0.8	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	2.2	0.5	-1.5	1.2	-1.4	0.5	0.3	0.4	0.7	0.7	0.3	0.6	1.2
Weight	0.3	1.5	2.7	1.4	-0.5	0.3	0.2	1.6	0.8	1.1	1.6	1.6	1.4	1.2	1.5
Time employed in main current job	0.3	0.4	1.0	-0.6	-1.0	-0.5	0.1	-0.5	-0.6	-0.5	-0.6	-0.6	-0.5	-0.6	-0.7
Father’s age at death	0.3	0.3	1.9	0.4	0.8	0.6	1.4	0.4	-0.2	0.2	0.3	-0.0	0.6	0.2	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.6	-0.5	1.0	1.6	0.8	-0.3	-0.8	-0.4	-0.4	-0.4	0.4	0.6	-0.4
Noisy workplace	0.3	0.4	1.3	-0.4	-0.1	0.0	1.1	-0.5	0.3	-0.5	-0.5	-0.4	-0.7	-1.0	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.0	0.9	0.6	1.3	-0.7	1.0	1.4	1.0	1.1	1.2	0.9	0.9	1.3
Arm fat-free mass (right)	0.3	1.4	3.5	1.2	-0.4	0.3	-0.6	1.4	0.9	0.9	1.4	1.6	1.1	1.3	1.9
Exposure to tobacco smoke outside home	0.3	0.4	0.8	0.1	0.4	-0.8	0.9	-0.7	-0.8	-0.3	-0.7	-0.8	-0.3	-0.1	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	2.3	-0.3	-1.2	-1.5	0.1	-0.1	0.4	-0.0	0.1	-0.2	0.0	-0.5	-0.8
Arm predicted mass (right)	0.3	1.7	4.2	1.2	-0.3	0.6	-0.4	1.6	0.8	1.0	1.6	1.7	1.4	1.6	2.0
Leg fat-free mass (right)	0.3	1.4	2.9	1.2	0.2	0.4	-0.3	1.5	0.3	1.0	1.5	1.5	1.4	1.6	1.7
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.2	-0.5	-0.5	1.0	-0.4	-0.2	0.4	-0.3	-0.3	-0.3	-0.7	-1.1	-0.6
Eye problems/disorders: Cataract	0.3	0.3	0.8	-0.4	0.3	-0.7	0.7	-0.7	-0.2	-0.5	-0.7	-0.5	-0.9	-0.8	-0.4
Mineral and other dietary supplements	0.3	0.4	1.3	0.6	0.8	1.1	0.2	0.3	-0.4	0.5	0.3	0.1	0.7	0.9	0.2
Osteoporosis (self-reported)	0.3	0.3	0.4	-0.5	0.6	-0.6	-0.5	-0.6	-0.6	-0.7	-0.6	-0.6	-0.6	-0.4	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	3.0	-0.3	-0.2	-1.7	-1.7	-0.2	0.3	-0.1	-0.1	-0.2	-0.4	-0.5	-0.2
Leg predicted mass (right)	0.3	1.3	2.8	1.1	0.2	0.4	-0.2	1.5	0.2	1.0	1.4	1.4	1.4	1.5	1.7
Medication: Atorvastatin	0.3	0.3	1.1	-0.5	0.4	0.8	-0.2	-0.6	-1.1	-0.6	-0.6	-0.5	-0.2	0.5	0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.2	0.6	1.5	-1.2	0.7	0.2	0.5	0.4	0.3	0.3	0.2	0.2	0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.9	0.7	-0.9	0.1	0.4	0.5	-0.2	0.7	0.6	0.4	0.9	0.9	0.3
Depressed Affect (Nagel 2018)	0.2	0.5	1.7	0.7	0.1	0.6	1.3	0.4	-0.1	0.6	0.5	0.3	0.9	1.1	0.4
Neuroticism (Nagel 2018)	0.2	0.6	3.1	0.7	0.8	1.8	1.2	0.1	-0.5	0.1	-0.1	-0.3	0.5	0.7	-0.3
Schizophrenia (2018)	0.2	0.4	1.5	-0.9	1.0	-0.5	-0.3	-0.6	-1.2	-0.8	0.0	-0.6	-0.1	0.4	-0.3
Major Depression (MDD)	0.2	0.3	1.8	-0.3	0.4	1.3	0.3	-0.2	-0.8	-0.4	0.0	-0.3	0.2	0.3	-0.3
Crohns Disease (2012)	0.2	0.4	1.5	0.7	0.1	0.5	1.2	0.7	0.5	0.8	0.0	0.4	0.5	-0.2	-0.1
Lung FEV1/FVC ratio	0.2	1.2	3.3	0.9	0.2	-0.2	-1.8	1.0	-0.1	0.8	0.9	0.9	1.3	1.8	1.4
Average weekly spirits intake	0.2	0.2	1.1	0.1	-0.4	0.0	-1.0	-0.2	-0.7	-0.2	-0.1	-0.4	0.1	0.2	-0.5
Age when periods started (menarche)	0.2	0.4	2.2	0.1	1.5	-0.6	0.6	0.6	0.7	0.1	0.4	0.6	0.2	0.1	0.7
Hearing difficulty/problems with background noise	0.2	0.3	0.7	-0.6	-0.2	0.6	0.1	-0.8	-0.5	-0.4	-0.7	-0.6	-0.6	-0.1	-0.3
Had menopause	0.2	0.3	1.1	0.6	-0.1	-0.1	0.4	0.4	-0.2	0.3	0.4	0.4	0.7	1.0	0.8
Pain all over the body in last month	0.2	0.2	0.7	-0.1	-0.3	0.6	0.3	-0.5	-0.4	-0.2	-0.5	-0.6	-0.2	-0.3	-0.8
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.4	0.6	0.4	0.9	-0.9	0.6	1.2	0.7	0.6	0.7	0.4	0.4	0.9
Tense / ‘highly strung’	0.2	0.4	1.4	0.8	-0.2	-0.1	-0.0	0.4	0.0	0.6	0.5	0.5	0.8	1.2	0.9
Hair/balding pattern: Pattern 4	0.2	0.6	3.2	-0.8	0.2	-0.1	-1.8	-0.5	-0.3	-1.0	-0.6	-0.2	-0.9	-0.2	0.6
Medication: Paracetamol	0.2	0.3	0.8	0.7	0.4	-0.1	0.4	0.6	-0.4	0.4	0.6	0.4	0.9	0.9	0.5
Leg fat percentage (right)	0.2	0.7	1.8	1.1	-0.5	0.1	1.3	0.8	0.5	0.8	0.9	0.8	0.9	0.6	0.5
Medication: Allopurinol	0.2	0.3	0.4	-0.6	-0.3	-0.3	-0.5	-0.6	-0.4	-0.6	-0.7	-0.7	-0.6	-0.4	-0.5
Medication: Omeprazole	0.2	0.3	1.5	-0.2	-1.2	-0.5	-0.4	-0.3	0.2	-0.4	-0.1	-0.1	-0.7	-0.6	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	1.2	0.6	0.4	-0.7	1.1	0.1	-0.2	0.1	0.0	-0.1	0.3	0.2	-0.2
Whole body fat mass	0.2	0.7	1.3	1.1	-0.1	0.1	0.5	1.1	0.2	0.7	1.1	0.9	1.1	0.9	0.7
Leg fat mass (right)	0.2	0.7	1.1	1.0	-0.6	-0.0	0.7	1.0	0.5	0.8	1.1	1.0	1.0	0.9	0.9
Alcohol intake frequency.	0.2	0.4	1.7	-0.3	1.3	0.4	0.2	-0.5	-1.2	-0.6	-0.6	-0.7	-0.1	0.2	-0.5
Number of full sisters	0.2	0.3	0.6	0.3	0.1	0.6	0.8	0.5	0.6	0.5	0.6	0.6	0.6	0.4	0.4
Family relationship satisfaction	0.2	0.2	0.6	-0.7	0.5	-0.3	-0.4	-0.5	-0.2	-0.8	-0.6	-0.3	-0.5	-0.1	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.6	0.6	0.5	0.5	-0.7	0.2	-0.6	0.4	0.3	-0.2	0.8	0.6	-0.5
Mood swings	0.2	0.4	1.0	0.9	-1.0	-0.1	0.9	0.4	0.3	0.8	0.3	0.4	0.6	0.8	0.6
Loneliness, isolation	0.2	0.3	1.3	-0.2	-0.6	0.6	-1.0	-0.2	-0.3	-0.1	-0.1	-0.0	0.3	1.1	0.6
Qualifications: nursing, teaching	0.2	0.3	1.7	-0.1	-1.3	0.1	0.9	0.1	0.3	0.2	0.1	0.1	-0.3	-0.6	-0.2
Guilty feelings	0.2	0.3	1.1	-0.3	-0.9	0.3	-0.6	-0.3	-0.6	-0.3	-0.3	0.0	0.1	1.0	0.9
Mother’s age at death	0.2	0.3	0.8	-0.7	-0.3	-0.9	-0.7	-0.2	-0.0	-0.5	-0.4	-0.2	-0.5	-0.6	-0.3
Eye problems/disorders: Glaucoma	0.2	0.3	1.4	-0.4	1.2	-0.8	-0.1	-0.2	-0.5	-0.4	-0.2	-0.3	-0.2	-0.3	-0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.8	0.3	-0.0	-0.9	0.4	0.7	0.1	0.3	0.7	0.5	0.8	0.5	0.3
Medication: Paracetamol	0.2	0.4	1.4	0.4	0.3	-0.3	0.0	0.6	-0.5	0.2	0.6	0.5	0.9	1.2	0.8
Cholesterol lowering medication	0.2	0.3	1.5	-0.2	-1.2	-0.9	-0.0	0.1	0.7	-0.1	0.1	0.1	-0.5	-0.9	-0.2
Impedance of whole body	0.2	0.9	2.8	0.8	0.6	1.3	1.3	0.7	1.7	1.1	0.7	0.7	0.5	0.0	0.3
Schizophrenia (2014)	0.1	0.2	1.3	-0.5	1.1	0.3	-0.3	-0.1	-0.7	-0.4	0.0	-0.2	0.2	0.2	-0.4
Blood White Count	0.1	0.9	3.2	0.7	-1.0	-0.0	1.7	0.9	1.8	0.9	0.8	0.9	-0.0	-0.8	0.4
BMI	0.1	0.3	0.6	0.6	-0.7	-0.1	0.0	0.8	-0.0	0.4	0.8	0.7	0.7	0.6	0.6
Pack years adult smoking proportion	0.1	0.2	1.9	-0.2	-0.2	-1.4	-0.2	-0.1	0.4	-0.2	-0.0	0.1	-0.3	0.0	0.4
Trunk fat percentage	0.1	0.3	0.7	0.8	-0.0	0.2	0.6	0.8	0.1	0.5	0.8	0.6	0.8	0.5	0.3
Average weekly fortified wine intake	0.1	0.2	0.6	-0.0	0.8	-0.5	-0.1	-0.3	-0.7	-0.1	-0.2	-0.4	-0.1	-0.2	-0.5
Taking other prescription medications	0.1	0.1	0.4	-0.1	0.2	-0.1	-0.3	0.3	-0.5	-0.2	0.5	0.3	0.4	0.6	0.6
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	0.3	0.4	-0.0	0.2	0.4	0.1	0.5	0.5	0.3	0.4	0.2	0.2
Body mass index (BMI)	0.1	0.2	0.6	0.5	-0.4	-0.6	0.1	0.5	-0.6	0.1	0.5	0.3	0.7	0.8	0.3
Trunk fat mass	0.1	0.6	1.2	1.0	-0.1	0.2	0.6	1.1	0.4	0.7	1.1	0.9	0.9	0.6	0.7
Number of incorrect matches in round	0.1	0.2	0.7	-0.2	-0.8	0.0	0.7	-0.0	-0.4	-0.2	-0.0	-0.3	-0.2	-0.5	-0.4
Fluid intelligence score	0.1	0.2	0.7	-0.7	-0.3	0.0	-0.6	-0.1	0.5	-0.4	-0.1	-0.0	-0.5	-0.8	-0.3
Impedance of arm (right)	0.1	0.6	1.7	0.7	0.5	1.1	1.3	0.6	1.3	1.0	0.6	0.4	0.4	-0.3	-0.2
Falls in the last year	0.1	0.1	0.4	0.4	-0.3	-0.4	0.2	-0.2	-0.6	0.1	-0.1	-0.3	0.3	0.5	-0.3
Depression (self-reported)	0.1	0.1	1.0	-0.1	-1.0	0.6	0.1	0.0	0.5	-0.0	0.1	0.1	-0.1	-0.2	0.0
Medication: Lansoprazole	0.1	0.1	0.6	-0.1	-0.1	-0.7	0.4	-0.2	-0.5	-0.1	-0.1	-0.1	0.2	0.6	0.1
Impedance of arm (left)	0.1	0.6	1.2	0.6	1.0	1.1	1.1	0.6	1.0	0.9	0.6	0.4	0.7	0.1	-0.0
Arm fat mass (right)	0.1	0.4	0.8	0.8	-0.3	0.3	0.3	0.9	0.0	0.5	0.9	0.7	0.9	0.7	0.5
Peak expiratory flow (PEF)	0.1	0.2	1.4	-0.1	0.5	0.8	-1.2	0.1	0.7	0.1	0.1	0.2	0.0	-0.1	0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	2.0	-0.5	0.6	1.4	0.5	-0.0	0.0	-0.2	-0.1	0.0	-0.0	-0.0	0.1
Body fat percentage	0.1	0.3	0.6	0.8	-0.1	0.1	0.7	0.7	0.1	0.5	0.7	0.5	0.7	0.4	0.2
Comparative body size at age 10	0.1	0.3	1.4	-0.3	-0.3	-1.2	-0.4	-0.4	-0.6	-0.6	-0.5	-0.4	-0.3	-0.0	-0.2
Medication for pain relief, constipation, heartburn	0.1	0.2	0.5	-0.4	0.3	0.5	0.3	-0.6	0.4	-0.2	-0.6	-0.4	-0.7	-0.7	-0.6
Migraine (self-reported)	0.1	0.1	0.3	-0.0	0.4	0.5	0.0	0.1	0.3	-0.0	0.0	0.2	-0.2	-0.1	0.5
Had major operations	0.1	0.2	0.7	-0.1	-0.8	0.8	-0.0	0.2	0.2	0.1	0.2	0.1	-0.2	-0.5	-0.1
Supplements: Vitamin C	0.1	0.1	0.3	-0.3	-0.3	0.3	-0.1	-0.4	-0.6	-0.3	-0.3	-0.4	-0.4	-0.3	-0.3
Arm fat percentage (left)	0.1	0.2	0.5	0.5	0.3	0.1	0.7	0.4	-0.6	0.2	0.4	0.1	0.7	0.6	-0.1
Friendships satisfaction	0.1	0.1	0.6	0.2	0.0	-0.8	-0.2	-0.2	-0.1	0.1	-0.2	-0.1	0.3	0.7	0.1
Arm fat mass (left)	0.1	0.6	1.2	0.9	-0.3	0.2	0.5	1.0	0.0	0.6	1.0	0.8	1.1	1.0	0.6
Number of self-reported non-cancer illnesses	0.1	0.2	0.7	-0.1	-0.7	-0.6	-0.8	0.2	-0.4	-0.2	0.3	0.2	0.1	0.2	0.3
Average weekly champagne plus white wine intake	0.1	0.1	0.5	-0.2	-0.5	-0.7	-0.4	-0.1	0.5	0.1	-0.1	-0.0	-0.3	-0.5	-0.3
Leg fat percentage (left)	0.1	0.2	0.7	0.7	-0.6	0.1	0.8	0.5	0.4	0.4	0.6	0.4	0.4	0.1	0.1
Irritability	0.1	0.2	1.6	0.3	-1.3	-0.3	-0.4	-0.3	0.1	0.0	-0.2	-0.1	-0.2	0.1	0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.5	0.1	-0.5	-0.7	-0.4	-0.1	0.4	-0.1	0.0	0.1	-0.4	-0.4	0.3
Alcohol drinker status: Previous	0.1	0.1	0.6	-0.1	0.8	-0.4	-0.1	-0.3	-0.6	-0.2	-0.3	-0.3	0.1	0.3	-0.1
Leg fat mass (left)	0.1	0.4	0.7	0.8	-0.5	-0.0	0.4	0.8	0.3	0.5	0.8	0.7	0.7	0.5	0.6
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.2	-0.3	0.2	0.4	0.3	0.2	0.1	-0.0	0.3	0.1	0.3	0.1	-0.2
Chronotype (morning person)	0.0	0.1	0.4	-0.2	-0.3	0.7	-0.3	-0.3	-0.1	-0.1	-0.3	-0.3	-0.3	-0.4	-0.3
Tanning	0.0	0.5	2.9	0.5	-1.7	1.1	-0.1	-0.0	0.9	0.6	-0.0	0.1	-0.2	-0.2	0.1
Arm fat percentage (right)	0.0	0.1	0.4	0.5	0.1	0.0	0.6	0.3	-0.4	0.2	0.3	0.1	0.5	0.2	-0.3
Gout (self-reported)	0.0	0.1	0.4	-0.0	-0.6	-0.5	0.1	0.1	0.3	0.1	0.1	-0.0	-0.0	-0.2	-0.1

Hub : Genes

C11orf1

Models

Trait associations