TWAS hub - ZNF229

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.203	0.0430	2.1e-11	0.119	0.124	0.172	0.18	0.151	2.5e-14	7.1e-15	2.0e-20	2.3e-21	5.1e-18
2	GTEx	Artery Tibial	0.200	0.0623	4.7e-04	0.061	NA	0.051	NA	0.034	1.6e-05	NA	7.2e-05	NA	1.1e-03
3	GTEx	Brain Cerebellum	0.234	0.0880	6.0e-03	0.119	NA	0.083	NA	0.084	2.3e-04	NA	2.0e-03	NA	1.8e-03
4	GTEx	Breast Mammary Tissue	0.203	0.0720	5.3e-03	0.043	NA	0.003	NA	0.040	3.0e-03	NA	2.1e-01	NA	3.8e-03
5	GTEx	Breast Mammary Tissue (Male)	0.341	0.1167	1.3e-02	0.092	NA	-0.003	NA	0.085	3.8e-03	NA	3.8e-01	NA	5.2e-03
6	GTEx	Cells Transformed fibroblasts	0.190	0.0480	1.8e-05	0.043	NA	0.114	NA	0.095	3.3e-04	NA	6.8e-09	NA	1.3e-07
7	GTEx	Esophagus Muscularis	0.175	0.0600	7.1e-03	0.040	NA	0.045	NA	0.039	1.8e-03	NA	9.8e-04	NA	1.9e-03
8	GTEx	Muscle Skeletal	0.113	0.0374	1.4e-03	-0.002	NA	0.003	NA	-0.003	7.4e-01	NA	1.7e-01	NA	8.6e-01
9	GTEx	Skin Not Sun Exposed Suprapubic	0.277	0.0770	1.8e-04	0.090	NA	0.085	NA	0.060	1.2e-05	NA	2.2e-05	NA	3.3e-04
10	GTEx	Stomach	0.272	0.0710	1.4e-04	0.044	NA	0.048	NA	0.077	3.5e-03	NA	2.5e-03	NA	1.5e-04
11	TCGA	Breast Invasive Carcinoma	0.022	0.0115	2.3e-03	0.001	0.010	0.000	NA	0.000	2.2e-01	3.0e-03	2.8e-01	NA	3.0e-01
12	TCGA	Colon Adenocarcinoma	0.084	0.0370	1.1e-03	0.017	0.044	0.025	NA	0.020	3.5e-02	1.4e-03	1.4e-02	NA	2.3e-02
13	TCGA	Thyroid Carcinoma	0.081	0.0280	1.8e-07	0.058	0.087	0.082	NA	0.083	2.7e-06	7.9e-09	2.1e-08	NA	1.7e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Alzheimer’s Disease (including proxy)	27.9	40.4	458.0	1.1	5.7	1.4	-1.5	-1.9	1.1	-2.7	-2.2	-21.4	-0.7	-1.2	-1.2	-3.0
Alzheimer’s Disease (in mother)	13.5	15.8	171.6	1.1	2.5	1.0	-1.1	-1.8	0.7	-2.5	-1.7	-13.1	-0.2	-0.7	-0.6	-3.1
Alzheimer’s Disease (in father)	7.5	8.2	91.2	0.4	3.3	1.1	0.6	-0.1	0.4	0.7	-0.3	-9.6	-0.4	-0.7	-0.8	0.0
LDL Cholesterol	4.1	6.4	57.0	2.7	-1.3	0.8	0.0	-0.7	-0.3	-1.4	1.5	-7.5	2.7	1.0	1.2	-1.7
High cholesterol (Self-reported)	4.1	7.2	65.4	0.5	-0.6	-1.8	-0.7	-1.5	-2.5	-1.6	1.0	-8.1	0.8	-0.9	-1.1	-3.1
Commuting to job workplace: Cycle	3.9	4.7	14.4	2.5	3.8	0.3	1.0	0.7	2.7	2.5	2.0	0.9	3.0	1.7	1.6	2.4
Coronary Artery Disease (CAD)	3.3	4.0	8.9	0.5	-2.0	-0.5	-2.1	-2.4	-1.7	-2.8	-1.7	-2.5	0.3	-1.7	-2.1	-3.0
Medication: Atorvastatin	3.3	4.1	24.0	-0.3	-0.2	-2.3	-1.4	-2.0	-2.1	-1.3	-0.6	-4.9	0.3	-1.4	-1.9	-2.5
Time employed in main current job	2.7	3.1	7.9	-1.5	-1.5	-2.3	-0.8	-1.7	-1.3	-0.7	1.4	-2.8	-0.9	-2.5	-1.9	-2.0
Commuting to job workplace: Car/motor vehicle	2.5	2.9	9.0	-1.7	-2.3	-1.8	-0.4	-0.8	-3.0	-2.0	0.5	1.3	-1.2	-1.7	-1.3	-2.2
Commuting to job workplace: Public transport	2.5	3.0	7.9	1.3	-0.9	1.5	0.9	1.3	1.8	2.1	1.0	1.3	0.5	2.6	2.8	2.5
Basal cell carcinoma (self-reported)	2.5	3.0	9.4	-2.4	-3.1	-0.8	-0.8	-0.9	-2.3	-1.8	0.8	-0.0	-2.7	-1.3	-0.8	-1.5
Average weekly fortified wine intake	2.3	2.7	10.8	-3.3	-1.0	-1.6	-0.1	-1.5	-1.6	-1.6	-0.3	0.2	-2.7	-0.8	-0.4	-2.2
Medication: Co-codamol	2.2	2.6	5.5	1.2	1.9	-0.8	1.6	1.5	1.3	2.4	1.2	1.0	1.2	2.1	1.6	2.2
Medication: Ventolin 100micrograms inhaler	2.2	2.8	8.9	2.4	0.6	1.6	0.8	1.7	1.4	0.8	-0.8	-0.7	1.5	3.0	2.5	1.7
Medication: Cholesterol lowering	2.1	3.3	28.5	-0.6	-1.9	-0.7	-0.4	-0.4	-2.1	-1.3	0.2	-5.3	-0.7	-0.3	-0.4	-1.7
Medication for cholesterol, blood pressure or diabetes	2.0	3.4	9.8	1.6	2.7	0.7	1.5	0.8	2.6	1.9	0.0	3.1	1.2	1.3	1.6	2.2
Medication: Blood pressure	2.0	3.6	6.7	-2.2	-2.5	-0.9	-1.7	-0.9	-2.6	-2.3	0.1	-1.2	-1.7	-2.1	-1.9	-2.5
Medication: Aspirin	2.0	2.7	8.1	-1.5	-2.9	0.5	-1.6	-1.2	-1.5	-2.7	-1.4	-0.7	-1.2	-0.5	-0.4	-2.6
Leg pain on walking	1.9	2.3	7.0	-2.6	0.9	-1.6	-0.4	-1.7	-1.9	-0.4	-0.7	-0.5	-1.7	-2.1	-2.0	-1.0
Medication: Aspirin	1.8	2.3	6.9	-0.8	-2.6	0.7	-1.8	-1.5	-1.3	-2.5	-1.5	-0.6	-0.3	-0.3	-0.1	-2.4
Cholesterol lowering medication	1.8	2.7	18.2	2.1	1.1	-1.2	-0.3	-0.4	-0.3	0.0	0.4	-4.3	2.4	1.3	0.9	-0.8
Medication: Atenolol	1.7	2.1	7.0	-0.9	-2.6	0.9	-1.6	-0.0	-1.5	-2.3	0.1	-1.7	-1.6	-0.7	-0.9	-1.3
Pain all over the body in last month	1.7	1.9	5.1	2.2	1.1	-0.7	0.8	0.3	1.4	1.5	1.3	-2.0	1.8	1.1	0.7	1.4
Illnesses of siblings	1.7	2.4	5.9	2.0	1.6	1.4	1.5	0.9	2.4	1.2	-0.5	1.2	1.5	1.6	1.8	1.6
Pulse wave Arterial Stiffness index	1.6	1.9	8.4	-1.5	-0.4	-2.9	0.9	1.2	-0.1	1.1	1.4	1.4	-1.5	1.0	0.8	1.5
Chronic bronchitis/emphysema (mother)	1.6	1.9	8.4	0.6	0.2	-1.4	0.7	0.4	0.3	2.4	2.2	1.0	0.7	0.6	0.8	2.9
Illnesses of father: Heart disease	1.6	2.2	10.1	3.2	-0.8	2.3	-0.9	-1.0	0.5	-0.7	-0.8	-0.7	2.8	0.9	0.5	-0.8
Hearing aid user	1.6	1.8	5.7	-0.3	-1.0	-0.7	-1.7	-1.3	-1.3	-2.4	-1.3	0.9	-0.2	-1.4	-1.5	-2.0
Cardiovascular Disease	1.5	4.9	16.6	-1.5	-2.8	-0.6	-1.3	-0.9	-3.2	-2.9	0.1	-4.1	-1.4	-1.4	-1.1	-3.2
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	6.6	0.0	-0.8	-0.5	-2.2	-1.8	-1.0	-1.2	-0.0	-1.3	-0.0	-1.9	-2.6	-1.0
Falls in the last year	1.5	2.1	3.9	-1.7	-0.7	-0.8	-1.3	-1.9	-1.8	-0.9	-0.5	-1.1	-1.4	-2.0	-1.7	-1.6
Medication: Amlodipine	1.5	2.1	5.3	-1.1	-1.2	-0.7	-0.3	-1.7	-2.0	-1.3	-0.2	-1.5	-1.2	-1.9	-1.4	-2.3
Pulse wave peak to peak time	1.5	1.8	9.9	1.5	0.5	3.1	-0.7	-1.0	0.4	-0.8	-1.5	-1.2	1.6	-0.7	-0.4	-1.2
Medication for pain relief, constipation, heartburn	1.5	2.5	6.6	2.5	2.1	1.1	1.0	0.0	1.2	2.3	-0.2	0.2	2.6	0.9	0.8	2.1
Hypertension (Self-reported)	1.5	4.1	9.4	-1.6	-2.7	-1.1	-1.9	-2.0	-3.1	-2.3	-0.9	-0.8	-1.4	-2.2	-2.4	-2.4
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	7.1	2.7	0.6	0.1	-1.1	0.1	1.3	0.0	-0.3	-0.6	2.4	2.1	1.4	0.4
Qualifications: None of the above	1.4	3.0	10.1	-3.1	-0.3	-0.2	-0.4	0.3	-1.6	-0.7	0.0	-0.3	-2.6	-3.0	-3.2	-0.7
Medication: Simvastatin	1.4	2.1	15.0	0.5	-1.6	0.2	-1.1	0.1	-1.8	-1.3	0.0	-3.9	0.1	0.7	0.7	-1.3
Illnesses of mother	1.4	1.8	9.8	0.2	-0.4	-0.2	1.4	1.2	2.0	0.6	1.1	3.1	-0.1	1.2	1.7	0.5
High blood pressure (siblings)	1.4	2.0	4.6	-1.2	-1.9	-1.2	-1.6	-0.9	-2.1	-1.3	0.8	-0.5	-0.8	-1.9	-1.7	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	4.4	1.9	0.7	0.4	0.9	0.0	2.1	1.3	0.8	1.4	1.7	1.4	1.1	1.5
Handedness (chirality/laterality): Left-handed	1.4	1.7	4.4	-0.8	-0.6	0.4	-1.7	-1.7	-0.7	-1.9	-1.0	-2.0	-0.6	-0.8	-0.7	-2.1
High blood pressure	1.3	3.6	8.4	-1.4	-2.1	-1.4	-2.2	-2.0	-2.9	-1.9	-0.7	-0.6	-1.1	-2.2	-2.5	-2.2
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	7.1	2.4	1.1	0.7	0.2	-0.3	1.2	1.1	-0.5	1.7	2.7	1.7	1.6	1.1
Vascular/heart problems diagnosed by doctor	1.3	3.5	9.7	1.2	2.2	1.1	2.2	1.8	3.1	2.0	1.2	0.7	0.8	1.9	2.4	2.0
Heart attack	1.2	1.6	7.7	-0.5	-2.8	-0.1	-0.3	0.3	-1.8	-1.0	-0.6	-2.0	-1.0	-0.6	-0.8	-1.2
Number of live births	1.2	1.7	5.3	-0.8	-1.1	0.6	-0.9	-1.4	-0.8	-2.1	-2.3	1.3	-1.3	-0.8	-1.0	-1.3
Loud music exposure frequency	1.2	1.3	3.3	1.1	0.4	0.7	1.6	1.5	1.6	1.3	0.6	-1.1	0.0	0.8	0.8	1.8
Medication: Allopurinol	1.2	1.5	6.1	-2.1	-0.1	-0.7	-0.4	0.5	-0.7	-1.6	-1.0	-0.5	-2.5	-1.3	-1.3	-0.9
Pulse rate, automated reading	1.2	3.9	8.7	1.9	2.7	-0.4	1.3	0.7	3.0	2.9	1.4	1.8	2.0	1.7	1.2	2.4
Medication: Gliclazide	1.2	1.3	3.3	0.2	-0.2	-1.8	0.3	0.8	1.6	1.3	1.3	1.6	1.3	1.2	1.0	1.1
Rheumatoid Arthritis	1.1	1.5	4.2	-1.7	-1.1	-0.6	-0.9	-0.3	-0.9	-1.3	-0.2	-1.6	-2.1	-0.7	-0.6	-1.9
Number of treatments/medications taken	1.1	2.0	8.4	-1.2	-1.6	-1.4	-0.7	-0.3	-2.0	-1.0	0.7	-2.9	-0.8	-1.0	-1.0	-1.8
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.5	0.5	1.1	-0.2	1.6	0.7	1.4	1.5	0.6	1.4	1.2	-0.1	0.0	1.6
Maternal smoking around birth	1.1	1.6	7.2	0.1	2.7	-1.0	1.0	0.8	0.8	1.8	1.1	2.0	0.4	0.3	0.1	1.2
Had menopause	1.1	1.3	5.7	0.0	0.4	-1.8	1.9	0.4	0.4	1.7	2.4	0.5	0.7	0.3	0.7	0.0
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	4.9	-0.8	0.0	-2.2	-0.9	-1.8	-0.6	0.2	1.0	-0.9	1.1	-1.1	-0.9	-1.0
Asthma	1.1	2.2	6.4	2.5	-0.1	2.5	0.6	0.6	0.9	-0.2	-1.9	-1.9	1.5	1.6	1.1	1.0
Back pain experienced in last month	1.1	1.6	4.5	-2.0	-0.3	-0.9	-0.9	-2.1	0.2	-0.7	-1.1	1.1	-1.2	-1.4	-1.5	-1.3
Supplements: Fish oil (including cod liver oil)	1.1	1.5	6.5	-2.0	-1.2	-2.5	-0.6	-0.8	-1.1	-0.7	0.1	-0.5	-0.4	-1.2	-1.0	-1.2
Risk taking	1.1	1.6	3.8	1.6	-0.7	1.9	0.9	1.1	1.9	0.6	0.1	-0.3	1.0	1.7	1.6	1.4
Heart attack/myocardial infarction (self-reported)	1.1	1.4	8.6	-0.0	-2.9	-0.0	-0.2	0.4	-1.5	-0.9	-0.5	-2.0	-0.8	-0.3	-0.5	-1.0
Ulcerative Colitis	1.0	1.5	5.2	-0.6	-0.7	-0.8	-0.8	-1.5	-1.2	-0.9	-0.1	-1.7	-0.4	-1.3	-1.5	-2.3
Severe depression (siblings)	1.0	1.1	2.8	-1.1	-1.3	0.4	-0.1	-0.5	-1.1	-1.1	-0.8	0.1	-1.5	-1.6	-1.7	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	5.1	-1.0	-0.4	-1.1	-2.2	-1.7	-1.7	-1.8	-1.6	-0.7	-0.5	-1.8	-2.2	-1.5
Alcohol intake versus 10 years previously	1.0	1.5	4.8	1.7	0.7	-0.5	0.8	1.2	2.2	0.2	0.4	1.6	1.3	1.7	1.3	0.4
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	4.5	2.1	0.3	1.4	0.5	-0.2	1.7	0.8	-0.8	-0.7	1.6	2.1	1.4	1.2
Eye problems/disorders: None of the above	1.0	1.2	5.3	-2.3	-1.0	-0.9	-0.1	-0.1	-1.4	0.0	0.5	-1.2	-1.4	-1.1	-1.2	-0.4
Average weekly red wine intake	1.0	1.5	3.2	1.4	-0.9	0.4	1.6	0.9	1.6	1.0	0.2	0.3	1.2	1.8	1.8	1.0
Mineral and other dietary supplements	1.0	1.3	5.0	1.6	1.7	2.2	0.8	0.7	1.5	0.9	0.0	0.6	0.2	1.0	0.6	0.8
Financial situation satisfaction	1.0	1.2	2.8	0.9	0.7	1.7	1.4	1.6	0.8	0.6	-0.5	0.3	0.0	1.5	1.3	1.4
Prostate Cancer	0.9	1.3	4.3	0.6	-0.1	-0.3	1.3	0.2	1.0	2.1	1.4	1.5	1.1	0.7	0.7	1.6
Mean Putamen Volume	0.9	1.0	4.9	-0.5	-2.2	1.1	0.8	0.5	-1.0	-0.4	0.3	0.9	-1.2	-0.9	-0.4	-1.0
HDL Cholesterol	0.9	1.4	9.7	-1.1	0.4	0.9	-0.4	0.2	-0.7	0.1	-1.6	3.1	-1.3	-0.8	-1.0	0.5
Triglycerides	0.9	1.4	5.1	-0.8	2.2	-0.3	-1.2	-0.9	0.4	-0.7	0.6	-2.2	-0.5	-1.4	-1.4	-0.8
Chronotype (morning person)	0.9	2.0	7.4	0.9	2.7	-1.2	-0.8	-2.1	-1.3	0.8	0.3	-0.6	1.8	-1.1	-1.5	-1.4
Ever had hysterectomy (womb removed)	0.9	1.0	2.8	0.1	0.2	-1.6	-0.4	-0.7	-0.6	0.3	1.7	-1.5	0.8	-1.2	-1.4	-0.9
Medication for hormone replacement therapy	0.9	1.0	1.9	0.5	0.6	0.9	0.9	1.2	0.9	1.3	0.6	1.0	0.7	1.4	1.3	1.3
Number of incorrect matches in round	0.9	1.5	3.8	-0.9	-1.5	0.9	-1.5	-0.0	-1.9	-1.8	-0.3	-0.5	-2.0	-0.6	-0.6	-1.4
Hair/balding pattern: Pattern 2	0.9	1.2	4.6	-0.3	0.4	0.5	-0.4	-2.1	-1.7	-0.8	-1.4	-0.6	-0.0	-1.5	-1.2	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	2.9	-1.7	-1.7	-0.9	0.6	1.1	0.3	-0.8	1.3	-0.0	-1.7	0.6	0.9	-0.6
Medication: Lansoprazole	0.9	1.0	2.8	0.6	-1.3	-0.1	-1.7	-1.1	-1.3	-1.4	-0.8	0.5	0.2	-0.5	-0.9	-1.2
Prospective memory result	0.9	1.1	3.0	-1.6	-0.8	-0.4	-0.3	-0.8	-1.2	-0.7	-0.4	-1.0	-1.1	-1.4	-1.3	-1.7
Birth weight	0.9	1.9	8.8	2.1	0.2	3.0	0.1	-0.5	0.4	-0.5	-2.1	0.2	1.6	1.2	1.3	-0.5
Emphysema/chronic bronchitis	0.9	1.0	3.7	-0.3	-1.3	0.1	-1.0	-0.8	-0.8	-1.9	-1.2	0.0	-1.1	-0.3	-0.5	-1.4
Number of full sisters	0.9	1.0	4.8	0.4	-0.3	0.3	-1.0	-1.6	-0.6	-1.3	-0.5	-2.2	1.0	-0.8	-0.8	-0.5
Had major operations	0.9	1.1	5.4	-0.4	0.1	0.8	-2.3	-1.5	-0.9	-0.9	-1.4	-0.8	0.5	-0.6	-1.1	-0.0
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.1	1.4	1.4	0.4	0.6	1.1	1.1	1.3	0.4	0.9	1.3	0.7	0.6	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	7.9	1.2	0.5	2.8	0.2	1.3	2.0	-0.2	-1.7	-0.2	-0.2	1.2	1.0	2.0
Asthma (self-reported)	0.9	1.7	5.4	2.2	-0.3	2.0	0.6	0.2	0.8	-0.3	-1.7	-2.3	1.3	1.3	0.8	0.7
Average weekly champagne plus white wine intake	0.9	1.2	6.0	-0.0	0.9	2.5	-0.4	0.2	-0.0	0.3	-2.0	1.3	0.2	1.0	0.7	0.8
Mother’s age at death	0.9	1.1	4.0	-0.8	0.2	-0.8	-0.9	-1.2	-1.2	-0.4	-0.4	2.0	-0.4	-1.4	-1.4	-1.0
Ever depressed for a whole week	0.9	1.1	2.8	1.5	-0.2	-0.1	-1.4	-1.7	0.1	-1.0	-0.0	-1.0	1.1	-1.0	-1.3	-1.3
Schizophrenia (2018)	0.8	1.7	3.7	0.6	1.9	0.0	1.3	1.0	1.2	1.4	-1.0	-1.1	1.1	1.5	1.7	1.9
Crohns Disease (2017)	0.8	1.7	5.8	0.0	-0.6	-0.5	1.4	2.4	0.6	1.1	1.5	1.1	-0.7	1.5	1.6	1.9
Blood White Count	0.8	5.6	12.5	-2.7	-2.7	2.6	0.6	-0.8	-3.0	-2.4	-3.2	0.3	-3.5	-2.2	-2.0	-1.9
Diabetes (mother)	0.8	1.0	2.6	-0.9	-1.1	0.5	-1.1	-0.6	-1.0	-1.5	-1.6	0.9	-1.0	-0.7	-0.8	-0.9
High blood pressure (mother)	0.8	1.1	8.1	-0.8	-0.8	-0.9	-0.5	0.3	-1.8	0.5	0.1	2.8	0.0	-0.5	-0.7	0.1
Had other major operations	0.8	1.0	3.4	1.0	0.9	0.3	0.8	1.0	1.0	0.7	-0.0	0.6	0.9	1.7	1.8	0.7
Father’s age at death	0.8	1.1	7.2	-0.1	-0.1	-1.5	1.0	0.1	0.5	1.3	1.0	2.7	0.4	-0.2	-0.0	0.1
Pulse rate	0.8	1.4	4.0	-0.8	1.3	-1.5	1.8	1.0	0.4	2.0	0.8	1.1	-0.2	0.9	0.9	1.3
Noisy workplace	0.8	1.0	4.5	-0.5	0.1	-1.9	0.8	0.5	-0.0	0.5	2.1	-1.2	-1.0	-0.9	-0.5	0.0
Exposure to tobacco smoke at home	0.8	0.9	2.7	0.2	1.6	-1.2	0.0	-0.3	0.1	1.5	1.4	-0.2	0.7	-1.1	-0.8	0.9
Health satisfaction	0.8	1.1	2.6	0.2	1.1	-0.8	1.6	0.6	1.2	1.6	0.2	0.1	0.3	1.3	1.6	0.9
Shortness of breath walking on level ground	0.8	1.0	2.3	-0.2	-0.9	-1.1	1.2	1.5	0.6	0.7	1.1	0.3	-0.4	1.5	1.4	0.6
Neck or shoulder pain in last month	0.8	1.1	2.7	-1.4	-0.7	-0.5	-0.2	-0.9	-1.5	-0.5	-0.1	-0.8	-0.9	-1.6	-1.5	-1.3
Chest pain or discomfort	0.8	1.1	3.5	1.5	1.2	-1.1	-1.1	-0.6	0.6	-0.0	0.6	-1.9	1.8	0.4	-0.1	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.5	1.3	-0.6	1.4	0.3	1.1	0.9	0.4	-0.4	1.1	0.8	1.6	1.4	0.6
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	4.3	0.9	-0.1	-0.7	-1.0	-1.7	-0.5	-0.6	1.5	-2.1	1.1	-1.1	-1.0	-0.5
Illnesses of father: None of the above (group 1)	0.8	1.0	5.2	-1.9	-0.0	-0.6	0.4	0.4	-1.0	-0.5	-0.6	1.2	-2.3	-0.1	0.4	-0.0
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.4	1.8	0.5	1.9	-0.0	-0.8	0.4	0.1	-0.8	0.9	1.7	0.2	0.1	0.2
Alcohol drinker status: Previous	0.8	1.0	2.4	1.3	1.2	-0.3	0.3	0.3	1.6	0.7	-0.1	-1.0	1.4	1.5	0.9	0.6
Breast Cancer	0.7	1.8	5.0	0.5	-0.4	0.8	2.2	1.8	1.8	0.8	1.7	0.8	-0.6	1.4	1.9	1.0
Bipolar Disorder (2011)	0.7	0.7	3.2	0.7	0.0	1.6	-0.2	0.0	0.9	0.5	-1.8	0.0	1.0	0.1	-0.3	0.5
Neuroticism (2016)	0.7	1.1	2.8	-0.5	-1.1	1.4	-0.5	-1.1	-1.5	-0.9	-1.7	-0.3	-0.7	-1.1	-1.0	-0.8
Hand grip strength (left)	0.7	1.8	9.8	-0.1	-0.5	3.1	-0.4	0.3	-0.6	-0.8	-1.7	2.9	-0.4	0.2	0.3	0.1
Relative age of first facial hair	0.7	1.4	5.3	-0.4	-2.3	1.5	-0.3	-0.7	-1.8	-0.6	-1.3	0.7	-0.3	-0.5	-0.5	-1.7
Systolic blood pressure, automated reading	0.7	2.2	4.5	-1.7	-0.8	-1.8	-1.9	-1.0	-1.7	-1.2	0.5	1.1	-1.1	-2.1	-2.1	-0.9
Vitamin and mineral supplements	0.7	0.9	3.7	1.5	0.5	1.9	-0.0	-0.9	1.3	0.5	-1.1	-0.3	0.7	0.9	0.8	0.1
Supplements: Zinc	0.7	0.8	1.5	0.3	0.4	-0.7	0.6	0.8	1.1	1.2	-0.1	1.2	1.1	1.0	1.0	1.1
Relative age voice broke	0.7	1.1	3.1	-1.4	-1.8	-0.3	-0.5	-0.1	-1.7	-1.0	0.3	-0.8	-1.2	-1.1	-1.0	-1.0
Chronic bronchitis/emphysema (father)	0.7	0.8	5.9	-0.7	0.4	-1.1	-0.6	-0.7	0.6	0.5	0.3	2.4	0.6	-0.3	-0.7	-0.2
Trunk fat mass	0.7	2.8	8.8	0.6	1.1	2.6	0.4	0.5	2.1	0.7	-2.8	3.0	0.2	0.8	0.6	2.3
Weight	0.7	3.3	10.9	0.5	-0.0	3.1	1.1	1.2	2.1	0.8	-2.1	3.3	-0.3	1.4	1.6	2.4
Mouth/teeth dental problems: Dentures	0.7	1.2	4.0	0.7	0.8	2.0	-1.9	-0.5	-0.3	-1.1	-1.9	0.6	-0.1	-0.5	-1.1	-0.3
Pulse wave reflection index	0.7	0.9	4.0	-0.7	-2.0	-0.8	-0.7	-0.4	-0.8	-1.4	0.5	0.5	-1.4	-0.2	-0.1	-0.5
Ever highly irritable/argumentative for 2 days	0.7	0.9	2.3	-0.2	-1.2	0.5	-1.0	-0.4	0.2	-1.5	-0.1	0.5	-1.5	-1.1	-1.3	-0.5
Mouth/teeth dental problems: Bleeding gums	0.7	1.0	2.6	-0.7	-0.5	0.5	1.0	0.9	-0.9	0.7	-1.6	1.6	-1.1	-0.0	-0.4	1.4
Number of children fathered	0.7	0.8	2.3	1.3	0.1	0.1	-0.4	0.3	0.6	0.6	-0.9	0.7	1.5	1.4	0.8	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.6	-0.2	1.0	-0.7	1.3	0.6	0.3	1.2	1.6	-1.0	0.4	-0.9	-1.1	0.4
Suffer from ‘nerves’	0.7	1.1	7.1	-0.2	0.8	-0.3	1.5	0.8	0.5	1.1	1.0	-2.7	-0.5	0.6	0.8	0.0
Family relationship satisfaction	0.7	0.8	3.3	0.3	-0.6	1.7	-0.6	-0.2	-0.6	-1.3	-1.8	-0.9	-0.2	-0.2	-0.4	-0.7
Ever had bowel cancer screening	0.7	0.8	4.2	0.4	1.0	-0.9	-0.8	-0.9	-0.8	-0.3	-1.2	2.1	0.8	0.1	-0.0	0.0
Friendships satisfaction	0.7	0.9	1.8	0.1	-1.0	1.1	-0.8	-0.1	-1.3	-1.3	-0.5	-1.2	-0.8	-0.9	-1.0	-1.1
Osteoarthritis (self-reported)	0.7	0.9	5.8	1.2	2.4	0.6	-0.2	-0.3	0.9	0.5	-0.4	-0.7	1.1	0.9	0.4	0.4
Pain type(s) experienced in last month: Hip pain	0.7	0.8	3.2	0.9	0.3	-0.1	-1.2	-1.8	-0.7	-0.0	-1.3	0.9	1.3	0.2	-0.4	-0.6
Ever smoked	0.7	1.2	4.1	1.4	1.5	1.5	-0.6	0.5	0.4	0.3	-0.4	2.0	1.1	0.4	-0.2	1.6
Heart disease (siblings)	0.7	0.9	2.3	0.2	-1.3	0.5	-1.3	-0.7	-1.3	-1.4	0.3	-0.6	-0.2	-0.7	-0.8	-1.5
Worry (Nagel 2018)	0.6	1.3	11.3	-0.5	0.2	-1.4	1.0	0.1	-0.2	0.3	0.9	-3.4	-0.4	0.2	0.5	-1.0
Ulcerative Colitis (UC)	0.6	1.1	5.4	-0.9	-0.8	-0.8	-0.7	-0.8	-2.3	-0.9	-0.3	-1.1	-0.5	-0.6	-0.7	-1.7
HbA1C	0.6	0.7	2.6	1.2	0.2	0.7	0.1	0.0	0.4	-0.2	-1.2	-1.1	1.6	0.9	0.4	-0.4
Heel T-Score	0.6	4.7	16.3	-1.8	-0.0	-0.4	-4.0	-2.6	-2.2	-3.4	-2.2	-0.9	-1.1	-1.8	-1.8	-2.3
Systolic Blood Pressure	0.6	2.9	6.2	-2.1	-1.9	-2.5	-1.4	-0.7	-2.2	-1.4	1.2	-2.4	-1.6	-1.5	-1.0	-1.2
Angina	0.6	0.8	4.5	1.1	-1.0	0.6	-0.2	0.7	-0.5	-0.3	0.2	-2.1	0.6	0.9	0.8	0.4
Medication: Metformin	0.6	0.8	2.4	-1.2	-1.4	-1.6	1.1	0.8	0.0	0.5	1.4	0.6	-0.6	-0.1	0.1	0.3
Leg fat-free mass (left)	0.6	3.3	8.7	0.5	-0.9	3.0	1.9	2.0	2.2	0.9	-1.3	2.1	-0.5	1.9	2.4	2.1
Trunk fat percentage	0.6	2.3	9.6	0.6	1.6	2.0	-0.4	-0.4	1.6	0.3	-3.1	2.6	0.5	0.3	-0.1	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	3.8	0.0	-0.7	-0.6	-0.6	-1.7	0.2	-0.3	0.3	-1.9	-0.3	-0.4	-0.8	-0.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.4	1.4	0.7	-0.0	-0.2	-1.6	0.4	0.2	-0.3	-0.8	1.3	-0.5	-0.5	-0.5
Supplements: Glucosamine	0.6	0.8	2.8	-1.1	-0.6	-1.7	-0.8	0.3	-1.0	-1.0	-0.1	-0.5	-0.7	1.1	1.2	-0.1
Leg predicted mass (left)	0.6	3.3	8.5	0.4	-1.0	2.9	1.9	2.0	2.2	0.9	-1.3	2.1	-0.6	1.9	2.4	2.0
Mouth/teeth dental problems	0.6	0.9	3.3	0.2	0.4	-0.9	1.1	0.9	0.9	0.9	1.8	-0.3	1.1	0.8	1.4	-0.0
Fluid intelligence score	0.6	1.3	2.9	-0.3	-1.6	1.6	-1.1	-1.2	-1.1	-1.7	-0.8	-0.5	-0.2	-1.2	-0.7	-1.5
Lung cancer (father)	0.6	0.8	2.5	-0.4	0.3	-1.6	-1.1	-1.0	-1.4	-0.1	-0.2	-0.6	-0.0	-1.0	-1.2	-0.4
Birth weight of first child	0.6	1.0	4.7	1.5	-0.7	2.2	-0.9	-0.4	0.1	-1.3	-1.4	0.1	0.7	0.2	0.4	-0.5
Peak expiratory flow (PEF)	0.6	1.3	3.1	1.6	0.3	1.7	0.1	0.5	1.0	0.1	-1.5	0.9	1.4	1.7	1.6	0.2
Number of full brothers	0.6	0.7	2.5	0.3	-1.0	1.6	-0.4	0.2	-1.1	-1.0	-0.8	-1.4	-0.1	0.3	0.4	0.1
Angina (self-reported)	0.6	0.7	3.4	1.1	-0.9	0.4	0.1	0.8	-0.3	-0.0	0.6	-1.9	0.6	1.0	0.9	0.5
Medication: Ibuprofen	0.6	0.8	2.8	-1.5	-0.6	-1.1	0.5	0.8	0.4	-0.6	1.0	-0.3	-1.7	0.5	0.6	-0.5
Medication: Seretide 50 evohaler	0.6	0.7	2.5	0.9	0.6	0.0	-0.6	-0.7	0.8	-0.4	-1.6	-1.2	0.8	1.2	0.6	-0.2
Whole body fat mass	0.6	2.3	8.7	0.4	0.8	2.7	0.2	0.2	1.5	0.3	-3.0	2.5	-0.1	0.5	0.4	2.0
Overall health rating	0.6	1.2	7.3	-1.1	-0.1	-1.7	-0.9	-1.1	0.1	-0.3	-1.0	-2.7	-0.8	0.2	-0.4	-0.5
Illnesses of siblings: Diabetes	0.6	0.8	3.8	-1.6	-1.1	-1.9	0.3	-0.1	-0.5	-0.1	-0.0	0.5	-1.2	0.4	0.3	-0.3
Leg fat-free mass (right)	0.6	3.4	8.0	0.4	-0.9	2.8	1.9	2.1	2.1	1.1	-1.3	2.2	-0.4	2.0	2.4	2.4
Commuting to job workplace: Walk	0.6	0.7	1.5	-0.9	0.0	-0.9	0.9	0.6	1.2	0.7	0.1	-0.1	-1.0	1.0	1.2	0.6
Eye problems/disorders: Cataract	0.6	0.7	3.3	1.8	-0.6	0.3	0.1	0.2	0.9	-0.8	0.6	0.0	0.7	1.3	1.2	-0.6
Medication for cholesterol	0.6	0.9	5.9	-0.2	0.1	0.1	1.0	1.2	0.9	0.7	0.1	2.4	-0.8	0.2	0.2	1.1
Leg predicted mass (right)	0.6	3.3	7.5	0.5	-0.9	2.7	1.9	2.1	2.1	1.2	-1.2	2.1	-0.4	1.9	2.4	2.4
Number of self-reported non-cancer illnesses	0.6	1.1	4.9	0.9	-0.6	0.5	-1.2	-1.0	-0.7	-1.6	-0.9	-2.2	0.0	0.1	-0.1	-0.9
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.6	0.6	-0.5	1.1	-1.1	-1.6	0.2	-0.7	-1.0	0.2	0.9	-0.2	-0.5	-0.9
Medication: Blood pressure	0.6	1.1	3.5	-0.2	-0.4	-1.0	-0.9	-1.8	-1.9	-0.7	-0.7	-0.1	0.5	-1.1	-0.9	-1.4
Crohns Disease (2012)	0.5	0.8	3.3	-0.4	-1.4	-0.4	1.0	1.8	0.5	0.5	0.8	0.8	-1.0	0.4	0.5	0.6
Fasting Glucose	0.5	0.6	1.9	-1.3	-0.4	0.9	0.1	0.3	-1.4	-0.8	-0.6	0.1	-1.1	-0.8	-0.4	0.1
Lupus	0.5	0.7	5.7	0.3	-1.0	2.4	-0.3	0.4	-0.6	-0.6	-1.0	0.5	-0.4	0.3	0.0	-0.2
BMI	0.5	2.9	14.5	0.2	-0.9	1.9	1.1	1.4	1.9	0.6	-0.7	3.8	-0.3	1.7	2.1	2.0
Smoking Status	0.5	1.1	6.6	0.8	-1.1	2.6	-0.7	0.2	-0.3	-1.2	-1.1	1.5	-0.5	0.0	-0.3	0.4
Allergy or Eczema	0.5	1.2	4.5	1.3	0.7	-0.8	1.3	0.2	1.1	1.6	1.5	0.2	2.1	0.4	0.4	0.4
Respiratory disease	0.5	1.2	5.7	1.2	-1.8	0.6	-0.0	-0.3	-0.8	-0.8	-1.4	-2.4	1.0	0.3	-0.1	-0.6
Frequency of depressed mood in last 2 weeks	0.5	0.6	2.0	0.7	1.0	0.9	0.6	0.3	1.4	0.7	0.2	-0.7	0.1	0.9	0.8	1.0
Diabetes (father)	0.5	0.6	1.4	0.3	0.8	0.4	1.1	0.1	0.6	1.2	-0.3	1.1	0.9	0.7	0.9	0.9
Hand grip strength (right)	0.5	1.5	7.3	0.5	0.8	2.7	0.3	1.3	0.8	-0.0	-0.5	2.1	-0.2	1.2	1.2	0.9
Current tobacco smoking	0.5	0.7	2.8	0.2	0.2	0.6	0.8	1.7	0.5	0.5	-0.1	0.2	-0.6	1.0	1.1	1.6
Stomach or abdominal pain in last month	0.5	0.6	1.9	0.6	0.1	0.1	0.1	0.8	1.1	0.6	1.2	0.2	0.1	1.4	1.1	1.0
Past tobacco smoking	0.5	0.8	2.7	-1.0	-0.6	-1.4	1.0	0.5	0.6	0.2	0.8	-1.6	-0.8	0.5	1.0	-0.9
Alcohol usually taken with meals	0.5	0.8	3.6	-0.4	-1.9	1.3	-0.5	-0.8	-0.9	-0.5	-1.2	-1.1	-0.4	-0.0	0.1	-0.2
Financial difficulties in last 2 years	0.5	0.7	2.9	-0.9	-0.3	1.7	-0.2	-0.0	0.0	-0.3	-1.5	-0.2	-1.3	0.9	0.7	0.0
Arm fat percentage (right)	0.5	1.8	6.7	0.4	1.0	2.1	0.4	-0.0	1.6	0.4	-2.6	2.1	0.1	0.4	0.2	1.9
Worrier / anxious feelings	0.5	0.9	1.8	1.3	0.0	1.3	1.1	0.3	1.3	0.6	0.8	-1.1	0.9	0.9	1.2	0.4
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.8	0.9	0.7	1.9	-0.3	0.0	0.4	0.7	-1.4	0.8	1.2	1.6	1.3	1.2
Arm fat mass (right)	0.5	2.2	7.1	0.3	0.3	2.7	0.7	0.4	1.7	0.4	-2.6	2.6	-0.2	0.6	0.6	1.9
Standing height	0.5	4.5	14.7	0.6	1.1	3.8	2.1	3.0	1.8	1.3	-1.3	2.9	-0.5	1.9	2.1	2.3
Length of working week for main job	0.5	0.5	1.3	0.9	0.1	0.7	-1.0	-0.1	0.6	-0.1	-0.4	1.1	0.9	0.8	0.7	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.8	1.1	0.1	0.8	0.7	0.4	0.8	1.0	-0.4	0.1	0.8	1.7	1.3	0.6
Gout (self-reported)	0.5	0.7	2.8	-1.7	-0.7	-1.0	0.8	0.6	-0.9	-0.3	-0.4	0.1	-1.6	-0.5	-0.2	-0.5
Body fat percentage	0.5	2.0	8.3	0.5	1.5	1.9	-0.3	-0.5	1.4	0.4	-2.9	2.3	0.4	0.2	-0.1	1.8
Exposure to tobacco smoke outside home	0.5	0.6	2.5	-0.4	-1.6	-0.5	0.5	1.6	-0.2	-0.2	0.2	0.6	-1.0	0.5	0.3	0.7
Age at first live birth	0.5	0.9	4.9	0.9	2.2	0.4	-0.3	-1.4	0.3	0.7	-0.2	-0.8	1.3	-0.5	-0.6	-0.2
Heart disease (mother)	0.5	0.6	4.2	-0.2	-0.2	0.0	-0.4	-0.0	-2.0	-0.7	-0.2	-0.4	-0.1	-0.9	-1.3	0.0
Leg fat mass (right)	0.5	1.8	5.5	0.1	0.8	2.3	0.5	0.4	1.4	0.6	-2.2	2.3	-0.1	0.5	0.4	2.0
Supplements: Vitamin C	0.5	0.5	2.9	0.3	0.1	-0.1	0.4	1.1	0.1	0.7	0.2	1.7	0.8	0.4	0.5	1.0
Knee pain experienced in last month	0.5	0.8	5.3	-0.4	1.7	-0.1	0.0	-0.5	0.6	-0.4	-2.3	0.6	-0.3	0.7	0.4	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.2	-0.2	-1.8	0.4	-0.8	-0.5	-0.3	-1.2	0.3	0.9	-0.7	0.4	0.6	-0.2
Smoking status: Previous	0.5	0.7	2.8	0.7	-0.2	1.7	-0.8	-1.0	-1.1	-0.4	-0.8	1.0	0.5	-0.6	-0.9	0.5
Whole body fat-free mass	0.5	2.8	8.1	0.1	-1.2	2.9	2.0	1.9	1.8	0.9	-0.8	2.1	-0.9	1.4	2.0	1.7
Whole body water mass	0.5	2.6	8.0	0.0	-1.3	2.8	1.9	1.8	1.6	0.7	-0.8	2.1	-0.9	1.3	1.9	1.6
Arm fat mass (left)	0.5	1.9	6.1	0.2	0.4	2.5	0.6	0.3	1.6	0.4	-2.3	2.5	-0.3	0.2	0.3	2.0
Medication: Paracetamol	0.5	0.8	2.2	-0.3	-0.6	-0.5	-1.5	-0.8	-0.9	-1.4	-0.3	-0.5	-0.7	-0.7	-0.5	-1.4
Medication: Lisinopril	0.5	0.7	3.1	-1.1	-0.2	-0.9	0.3	-0.8	-1.8	0.4	0.1	-0.3	-0.5	-1.1	-0.8	-0.8
Basal metabolic rate	0.5	3.0	9.1	0.1	-0.9	3.0	1.8	1.9	1.9	0.8	-1.2	2.4	-0.9	1.4	1.9	2.0
Fractured/broken bones in last 5 years	0.5	0.6	1.3	0.2	-0.9	0.6	0.9	1.2	0.3	0.6	0.8	1.2	-0.5	0.5	0.5	1.2
Diastolic blood pressure, automated reading	0.5	1.4	3.6	-1.7	0.4	-1.9	-1.2	-0.1	-0.9	-0.0	0.5	1.9	-1.1	-1.2	-1.5	0.6
Supplements: Calcium	0.5	0.6	2.2	-1.0	0.6	-0.5	1.5	1.0	0.0	0.8	0.8	0.4	-0.7	-0.3	-0.3	0.7
Leg fat mass (left)	0.5	2.1	6.8	0.3	0.9	2.2	0.6	0.5	1.5	0.9	-2.2	2.6	0.1	0.7	0.7	2.3
Bipolar Disorder or Schizophrenia	0.4	0.9	2.8	0.1	1.7	0.4	1.1	0.7	0.8	0.7	-1.7	-0.0	0.3	0.8	1.2	1.1
Major Depression (MDD)	0.4	0.5	2.4	1.5	-0.2	0.3	-0.7	-0.2	1.1	0.0	-0.1	0.8	1.5	0.2	-0.2	-0.1
Primary Biliary Cirrhosis	0.4	0.6	3.1	1.2	0.1	0.9	-0.7	-0.8	-0.2	-0.1	-0.5	0.0	1.8	-0.4	-0.8	-0.1
Schizophrenia (2014)	0.4	1.0	2.4	0.3	1.1	0.2	1.3	1.0	1.2	0.7	-1.1	-0.1	0.6	1.1	1.6	1.2
Type 2 Diabetes (T2D) (2012)	0.4	0.5	3.0	1.0	-1.7	-0.1	-0.4	-0.8	-0.2	-0.3	0.1	-0.7	0.8	0.2	-0.1	0.2
Neuroticism	0.4	1.0	3.6	-1.7	-0.5	-1.9	0.1	-0.4	-0.8	-0.2	0.9	-1.0	-1.5	-0.6	-0.3	-1.0
Hearing difficulty/problems: Yes	0.4	0.6	1.6	1.3	0.9	0.5	-1.0	-0.9	-0.1	0.4	-0.5	0.7	1.0	0.5	-0.0	1.0
Ever used hormone-replacement therapy (HRT)	0.4	0.4	1.5	0.2	0.4	-1.1	-0.5	-1.2	0.5	-0.3	0.3	0.4	1.0	-0.2	-0.3	-1.0
Fed-up feelings	0.4	0.7	2.5	-0.2	-0.7	-0.3	0.5	0.8	1.6	0.0	0.5	-0.9	-0.8	1.2	1.2	0.5
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.4	1.2	0.1	-0.6	0.7	-0.4	1.0	0.6	1.1	-0.1	0.7	0.1	0.4	0.4
Qualifications: CSEs or equivalent	0.4	0.6	2.4	-0.5	-0.0	-1.4	-1.5	-1.1	0.5	0.2	-0.2	-0.6	0.5	-0.2	-0.5	-0.8
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.7	0.7	0.9	-0.2	1.5	-0.1	0.9	1.4	1.4	-0.5	1.6	-0.3	0.1	0.1
Sitting height	0.4	3.0	6.4	0.9	1.1	2.5	2.4	2.5	1.9	1.4	0.2	0.6	-0.1	1.9	2.2	2.0
Nervous feelings	0.4	0.8	6.3	0.5	0.4	-0.7	0.7	0.3	0.4	0.4	0.5	-2.5	0.3	0.9	0.7	-0.4
Hearing difficulty/problems with background noise	0.4	0.6	2.7	-0.1	0.1	0.5	-1.1	-1.3	-1.2	0.4	-1.6	0.1	0.4	0.4	-0.3	0.3
Allergy	0.4	0.9	4.2	-1.1	-0.3	-0.3	-1.6	-0.4	-0.9	-0.7	-0.8	2.1	-0.8	-0.2	-0.5	-0.2
Trunk fat-free mass	0.4	2.4	7.0	-0.4	-1.4	2.6	2.0	2.0	1.3	0.6	-0.5	2.1	-1.4	1.0	1.7	1.4
Hip circumference	0.4	1.6	7.0	-0.6	0.3	2.3	0.0	0.3	1.4	-0.3	-2.6	1.8	-0.9	0.3	0.5	1.4
Happiness	0.4	0.5	3.7	-0.3	-0.6	-0.7	0.3	-0.2	0.1	-0.2	0.6	-1.9	-0.5	-0.3	0.1	-0.6
Depression (self-reported)	0.4	0.5	2.4	0.6	-0.1	1.1	-0.6	0.0	-0.3	-0.6	-0.6	-1.5	-0.4	-0.5	-1.0	0.3
Trunk predicted mass	0.4	2.3	7.0	-0.4	-1.4	2.6	1.9	2.0	1.3	0.5	-0.6	2.1	-1.3	1.0	1.6	1.3
Breastfed as a baby	0.4	0.5	1.8	0.9	0.3	0.5	-0.7	-0.4	-0.2	-0.4	-1.1	-0.8	1.3	-0.2	-0.1	-0.3
Medication: Paracetamol	0.4	0.6	2.7	-0.4	-0.6	0.1	-1.2	0.0	-0.0	-1.6	-0.1	0.5	-0.7	-0.6	-0.6	-1.4
Comparative body size at age 10	0.4	1.2	4.4	1.0	-0.6	1.1	0.8	0.8	1.0	-0.3	-0.4	2.1	0.1	1.7	1.8	0.3
Worry too long after embarrassment	0.4	0.6	3.2	-1.0	0.3	-0.9	0.3	0.2	0.1	0.5	1.8	1.3	-0.6	-0.6	-0.3	-0.1
Migraine (self-reported)	0.4	0.6	2.3	-0.9	0.9	-1.3	0.1	-0.6	1.0	0.3	-0.2	1.5	-0.3	-0.1	-0.3	0.3
Medication: Omeprazole	0.4	0.5	1.6	-0.5	-0.8	-0.5	0.4	1.1	0.4	-0.1	-0.0	0.6	-1.1	1.3	0.9	-0.5
Alcohol intake frequency.	0.4	0.8	3.3	1.3	-0.2	1.2	-0.4	0.9	1.8	-0.4	-0.1	0.5	0.7	1.3	0.8	0.5
Comparative height size at age 10	0.4	2.4	7.1	-0.8	0.6	1.5	1.3	2.5	1.3	0.8	-0.2	2.7	-1.3	1.5	1.6	1.8
Age at last live birth	0.4	0.6	2.9	0.4	1.7	-0.4	-0.4	-1.5	-0.3	0.2	-0.8	-0.4	1.3	-0.0	-0.1	-0.2
Arm fat percentage (left)	0.4	1.6	6.2	0.3	0.8	1.9	0.1	-0.2	1.5	0.2	-2.5	2.2	0.1	0.2	-0.0	1.8
Mood swings	0.4	0.7	3.2	-0.9	0.0	-1.8	0.1	0.4	0.4	0.2	0.6	-1.4	-0.8	1.0	0.7	-0.1
Loneliness, isolation	0.4	0.5	2.4	-1.3	-0.9	-0.5	-0.8	-0.3	0.0	-0.9	-0.6	-0.0	-1.5	0.2	0.3	-0.1
Long-standing illness, disability or infirmity	0.4	0.6	4.3	0.2	-0.9	-1.2	-0.4	-0.5	0.1	-0.2	0.0	-2.1	0.2	0.7	0.2	-0.4
Arm fat-free mass (left)	0.4	1.8	6.3	0.1	-0.8	2.5	1.6	1.2	1.4	0.7	-0.8	2.1	-0.6	0.9	1.4	1.4
Number of operations (self-reported)	0.4	0.7	1.6	1.1	-0.3	1.1	-0.1	-0.1	0.3	0.0	-1.1	1.2	1.0	1.0	0.9	0.5
Irritability	0.4	0.7	1.3	0.7	1.1	-1.0	0.1	0.6	1.0	0.9	0.4	1.1	1.0	1.1	1.0	0.3
Age started oral contraceptive pill	0.4	0.6	3.8	-0.6	0.3	-1.9	-0.4	-0.6	-0.3	-0.1	0.9	0.8	0.3	-0.3	-0.4	-0.7
Unable to work because of sickness or disability	0.4	0.6	2.0	0.5	-1.4	1.3	0.7	0.2	0.5	0.6	-0.6	-1.3	-0.4	0.3	0.3	0.1
Arm predicted mass (left)	0.4	2.3	5.6	0.2	-0.9	2.4	1.8	1.6	1.6	1.0	-0.6	2.2	-0.6	1.3	1.9	1.7
Bipolar Disorder (2018)	0.3	0.5	2.0	-0.6	0.7	0.5	0.2	-0.1	-0.1	-0.7	-1.4	1.2	-0.9	-0.6	-0.2	-0.6
Depression (Nagel 2018)	0.3	0.4	2.2	0.3	-0.3	0.6	-0.5	-1.1	0.4	-0.5	-0.5	-1.5	-0.2	0.3	0.0	-0.6
Schizophrenia vs Biploar Disorder	0.3	0.4	1.1	-0.9	-1.0	-1.0	-0.3	-0.2	-0.5	0.0	0.3	-1.1	-0.1	0.6	0.6	0.2
Reaction Time	0.3	0.6	2.1	-0.8	-0.2	0.3	1.4	1.3	-0.5	0.4	-0.2	-0.1	-1.3	0.4	0.4	0.8
Age at First Birth	0.3	0.5	1.5	-0.3	1.2	1.1	0.1	-0.1	0.7	-0.3	-0.5	0.1	-0.7	-1.1	-0.8	0.2
Blood Platelet Count	0.3	3.7	14.0	-2.7	-2.4	0.4	2.3	2.6	0.9	-0.5	0.7	2.6	-3.7	-0.2	0.8	0.3
Height	0.3	5.5	18.2	0.8	2.2	4.3	1.8	2.2	2.2	1.3	-2.0	4.2	-0.1	1.4	1.4	2.7
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.5	-0.3	-0.8	-0.8	0.9	0.9	0.1	1.0	1.2	-0.7	0.5	-0.2	-0.2	0.7
Townsend deprivation index at recruitment	0.3	0.4	2.4	-0.3	-1.1	0.4	0.5	0.1	-0.4	-0.1	-0.6	1.6	-0.3	-0.3	-0.5	0.1
Taking other prescription medications	0.3	0.5	1.6	1.1	-0.9	0.1	-0.0	0.8	-0.1	0.3	-0.1	-0.8	0.8	1.3	0.6	0.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.1	1.0	0.4	0.4	-0.7	-0.1	0.6	0.2	0.1	1.1	0.7	0.4	0.0	0.3
Body mass index (BMI)	0.3	1.1	4.7	0.2	-0.6	1.5	0.1	-0.1	1.2	0.1	-1.6	2.2	-0.1	0.4	0.5	1.4
Waist circumference	0.3	1.1	3.9	0.2	-0.2	1.6	-0.8	-0.3	0.7	-0.3	-1.9	2.0	0.1	-0.2	-0.3	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.3	-0.2	-0.9	0.2	0.5	-0.1	0.4	0.1	0.8	-1.5	-0.8	0.6	0.6	-0.7
Forced vital capacity (FVC)	0.3	1.1	3.0	0.5	1.7	-0.1	0.8	0.9	1.3	1.0	-0.2	1.1	0.7	1.5	1.5	0.4
Diabetes (self-reported)	0.3	0.4	1.2	0.1	-0.6	-0.3	0.9	0.8	0.4	0.9	0.3	1.1	0.4	0.3	0.3	0.9
Hair/balding pattern: Pattern 3	0.3	0.4	2.7	0.1	1.6	-0.4	-1.1	0.1	-0.1	0.6	0.0	0.1	0.7	-0.2	-0.7	0.5
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.7	0.1	0.8	0.3	1.1	1.2	1.0	0.9	-0.1	1.2	0.1	1.5	1.6	0.3
Tense / ‘highly strung’	0.3	0.4	2.0	0.5	1.1	0.6	0.7	-0.4	0.1	0.7	-0.6	-1.4	0.1	0.3	0.1	0.2
Hair/balding pattern: Pattern 4	0.3	0.8	2.3	0.1	-1.1	-0.0	0.9	1.2	0.7	-0.7	1.2	-0.2	-0.6	1.2	1.5	-0.4
Headache pain in last month	0.3	0.6	2.5	0.4	-0.3	1.6	-0.2	0.4	1.4	-1.1	-0.6	0.2	-0.4	0.8	0.7	0.2
Arm fat-free mass (right)	0.3	1.7	4.4	0.1	-1.0	2.0	1.4	1.5	1.4	0.7	-0.3	2.1	-0.8	1.0	1.5	1.5
Wheeze or whistling in the chest in last year	0.3	0.5	2.9	-0.7	-1.7	0.2	0.3	0.1	-1.1	-0.2	-0.4	-0.6	-1.0	0.1	0.0	0.0
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.7	-0.4	0.7	0.4	0.7	-0.3	0.1	0.2	-0.9	0.4	-0.8	0.6	0.6	0.4
Arm predicted mass (right)	0.3	1.5	4.5	0.1	-0.9	2.1	1.3	1.3	1.3	0.7	-0.7	2.0	-0.7	0.8	1.3	1.3
Diabetes diagnosed by doctor	0.3	0.5	1.7	-0.6	-1.3	-1.1	0.8	0.4	-0.2	0.7	1.3	0.1	0.0	-0.5	-0.4	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	2.3	0.1	0.3	-0.5	1.5	1.2	0.3	0.0	0.2	0.2	-0.6	0.5	0.4	0.4
Breast cancer (self-reported)	0.3	0.3	1.4	-0.6	0.7	-0.1	0.4	0.3	-0.7	0.2	-1.2	-0.6	-0.2	0.9	0.3	-0.2
Osteoporosis (self-reported)	0.3	0.4	1.6	-0.7	-0.4	-0.2	-0.7	-0.1	-0.2	-1.2	0.7	-0.7	-0.9	-0.2	-0.1	-0.4
Smoking status: Current	0.3	0.5	1.7	0.4	0.4	0.5	0.6	1.3	0.5	0.4	-0.3	0.2	-0.5	0.9	0.9	1.3
Wears glasses or contact lenses	0.3	0.4	1.3	0.6	0.4	0.4	-0.5	-0.4	0.6	0.3	-0.1	-1.2	0.8	0.7	0.8	0.4
Ever taken oral contraceptive pill	0.3	0.4	1.8	-0.1	-1.4	0.0	0.3	-0.1	0.7	0.5	0.7	-0.1	0.4	0.7	0.8	-0.1
Illnesses of father: High blood pressure	0.3	0.3	1.6	-0.1	-0.9	0.4	-0.4	-0.1	-0.1	-0.3	-0.8	1.3	0.1	-0.4	-0.7	0.0
Leg fat percentage (left)	0.3	1.0	2.9	0.0	1.4	1.1	-0.0	-0.5	0.7	0.8	-1.7	1.7	0.4	-0.1	-0.3	1.6
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.4	-0.3	-0.8	-1.2	0.1	0.7	0.2	-0.2	0.1	0.6	-0.9	1.1	0.6	-0.5
Pain experienced in last month	0.3	0.6	1.3	1.1	-0.4	1.2	-0.7	1.2	-0.4	-0.2	0.4	0.9	0.9	0.2	0.6	0.5
Depressed Affect (Nagel 2018)	0.2	0.5	1.4	-1.1	-1.2	-0.9	-0.2	-0.1	0.1	-0.8	-0.4	-0.4	-1.1	0.4	0.3	-0.8
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.8	1.7	-0.6	1.2	-0.1	0.2	0.9	-0.2	-0.3	0.2	1.1	1.0	1.1	0.2
Irritable Bowel Disease (IBD)	0.2	0.5	1.7	-0.8	-1.2	-0.8	-0.0	0.6	-1.3	-0.2	0.6	-0.6	-0.8	-0.0	-0.0	-0.2
Ovarian Cancer	0.2	0.3	1.0	-0.5	0.5	0.4	0.3	-0.3	-0.7	0.4	-0.5	0.3	0.2	-1.0	-0.6	0.7
Blood Eosinophil Count	0.2	1.2	3.2	1.8	-1.7	1.7	-0.2	-0.2	-1.1	-0.1	-0.3	0.8	1.8	0.6	1.1	0.2
Blood Red Count	0.2	2.0	14.8	-1.6	1.0	-3.9	-0.1	-1.7	0.2	0.7	1.6	0.7	-0.4	-0.3	-0.4	-0.8
Waist Hip Ratio (WHR)	0.2	0.8	2.2	1.2	-1.2	-0.8	-0.9	-0.3	-1.1	-0.3	0.8	0.9	1.5	-0.5	-0.9	-0.6
Lung FEV1/FVC ratio	0.2	1.0	4.2	0.2	-0.3	1.2	1.5	0.9	0.2	1.0	0.2	2.1	-0.5	0.9	1.3	0.4
Lung FVC	0.2	1.1	4.4	0.3	2.1	-1.1	0.3	-0.0	1.2	1.4	0.3	1.6	1.3	0.3	0.1	0.1
Average weekly spirits intake	0.2	0.3	1.1	0.6	0.7	0.1	-0.4	0.1	1.1	0.2	0.4	-0.7	-0.1	0.7	0.4	0.7
Sensitivity / hurt feelings	0.2	0.4	1.8	-0.1	-1.4	-0.4	-0.0	0.9	-0.1	-0.2	-0.2	-0.5	-0.5	0.7	0.9	0.5
Pack years adult smoking proportion	0.2	0.3	1.5	0.3	-0.6	0.7	0.5	0.1	0.2	0.4	1.2	-0.2	0.2	-0.6	-0.6	-0.2
Impedance of leg (right)	0.2	1.1	4.7	-0.7	2.2	-0.6	-1.1	-0.4	-0.9	-0.8	0.3	-0.4	-0.2	-1.3	-1.6	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.2	-0.1	0.2	-0.7	-1.5	-0.3	-0.3	-1.4	-0.8	-0.0	-0.3	-0.3	-0.7	-0.5
Multivitamins +/- minerals	0.2	0.3	2.1	-0.6	0.1	-1.5	0.2	0.7	-0.5	-0.8	0.3	0.1	-0.1	0.0	-0.0	0.0
Medication: Levothyroxine sodium	0.2	0.3	2.1	-0.3	-0.5	-0.5	0.6	0.4	-0.0	0.5	-0.1	-1.4	0.5	0.1	-0.2	0.1
Impedance of leg (left)	0.2	1.0	6.2	-0.4	2.5	-0.7	-1.2	-0.5	-1.0	-0.2	0.2	-0.1	0.3	-1.0	-1.5	-0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.5	0.6	-0.5	0.3	-0.7	0.1	-0.2	-1.2	0.3	0.0	0.2	-0.0	-0.4	-0.6
Neuroticism score	0.2	0.3	1.5	-0.6	-0.4	-0.6	-0.0	-0.2	0.5	0.0	0.7	-1.2	-0.9	0.4	0.6	-0.3
Impedance of arm (right)	0.2	0.8	6.3	0.3	2.5	0.9	-0.2	0.2	0.5	-0.3	-1.7	-0.2	0.4	0.2	-0.3	0.1
Blood clot in the leg (DVT)	0.2	0.3	0.9	-0.0	1.0	-0.9	0.2	0.5	0.6	-0.1	0.5	-0.0	-0.6	0.5	0.4	0.0
Leg fat percentage (right)	0.2	0.8	2.6	-0.2	1.3	1.2	-0.0	-0.4	0.7	0.4	-1.6	1.5	-0.0	-0.3	-0.5	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.4	0.0	0.4	1.2	0.5	0.1	-0.6	0.3	-0.2	-0.8	0.2	0.6	0.4	0.1
Qualifications: College or University degree	0.2	0.6	2.0	0.5	-1.0	0.8	-0.5	-0.1	0.6	-1.3	-0.0	-0.3	0.1	0.9	1.4	-0.4
Mean time to correctly identify matches	0.2	0.5	1.9	-0.8	-0.3	-0.7	0.7	0.6	-1.4	0.2	-0.6	0.6	-0.9	0.2	0.0	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.9	0.3	0.0	0.7	0.1	0.1	0.5	-0.7	0.2	0.9	-0.1	0.4	0.4	-0.7
Qualifications: nursing, teaching	0.2	0.3	2.0	0.3	0.3	0.6	-0.1	-1.1	0.1	0.0	-1.4	0.0	0.3	0.3	0.2	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.4	0.1	-0.4	0.1	1.1	0.2	0.9	1.2	0.5	0.3	0.7	0.6	0.8	-0.5
Miserableness	0.2	0.4	1.1	-0.6	-0.7	-1.0	0.5	-0.6	0.2	0.1	1.1	-0.2	-0.9	-0.0	0.2	-0.0
Guilty feelings	0.2	0.4	1.2	0.5	-0.8	0.8	0.5	0.4	0.0	-0.0	-0.1	1.1	-0.3	0.7	0.9	0.2
Eye problems/disorders: Glaucoma	0.2	0.3	0.8	-0.4	-0.9	-0.4	-0.5	-0.6	-0.3	-0.6	-0.4	-0.2	-0.6	-0.6	-0.4	-0.7
Medication: Bendroflumethiazide	0.2	0.3	1.7	-0.5	-0.8	-1.3	-0.3	0.0	-0.9	0.2	0.3	-0.8	-0.4	0.2	-0.0	-0.1
Alcohol drinker status: Never	0.2	0.3	1.0	1.0	-0.2	0.0	-0.2	-0.0	0.7	-0.0	0.2	-0.2	0.9	0.7	0.8	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.7	-0.0	0.8	-0.9	0.0	0.5	0.6	-0.3	0.4	0.1	-0.6	0.5	0.3	-0.2
Pack years of smoking	0.2	0.3	1.4	0.3	-0.8	0.7	0.3	0.1	-0.1	0.2	1.2	0.2	0.0	-0.7	-0.8	-0.3
Impedance of whole body	0.2	1.0	7.0	0.1	2.6	-0.2	-1.3	-0.6	-0.3	-0.4	-0.6	-0.2	0.6	-0.7	-1.4	-0.4
Neuroticism (Nagel 2018)	0.1	0.3	1.2	-0.3	-0.5	-1.1	0.4	0.3	-0.1	-0.2	0.1	-1.1	-0.3	0.7	0.8	-0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.4	1.8	0.6	-1.1	1.3	0.1	0.0	0.4	-0.1	-0.4	0.5	0.5	0.2	0.4	0.2
Body Mass Index (BMI) (2010)	0.1	0.1	0.4	-0.4	-0.6	-0.5	-0.2	-0.4	-0.3	0.0	0.1	0.0	-0.3	0.2	0.3	0.4
Hypothyroidism (self reported)	0.1	0.2	0.5	-0.3	-0.4	-0.7	0.1	-0.1	-0.6	-0.2	0.4	-0.2	0.7	-0.1	-0.2	-0.5
Hair Pigment	0.1	1.5	4.4	1.4	1.0	2.0	-0.9	1.2	0.9	-0.6	-2.1	0.0	1.5	1.2	1.1	0.5
Tanning	0.1	1.5	3.4	-1.8	-1.1	-1.0	-1.3	-1.2	-1.8	-0.9	-0.1	-1.2	-1.8	-0.8	-1.0	-0.8
Age when periods started (menarche)	0.1	0.3	1.0	0.7	-1.0	0.0	0.9	0.4	0.2	0.5	0.7	0.1	0.5	0.2	0.4	-0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.5	0.2	-0.7	-0.1	0.0	-0.7	0.2	-0.3	-0.2	0.1	-0.6	0.2	0.4	0.3
Medication: Ramipril	0.1	0.2	0.6	0.6	-0.3	-0.3	0.2	0.0	-0.5	0.2	0.6	0.6	0.8	-0.2	-0.3	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.5	1.2	-0.7	0.1	1.1	1.0	1.0	0.2	0.3	-0.7	0.2	-0.8	0.5	0.8	-0.3
Impedance of arm (left)	0.1	0.6	4.3	0.1	2.1	0.1	-0.9	-0.2	0.2	-0.4	-1.3	-0.1	0.3	-0.2	-0.7	-0.0
Glaucoma (self-reported)	0.1	0.2	1.2	-0.2	0.1	-1.1	-0.3	-0.1	0.1	0.5	0.6	-0.1	0.0	-0.1	0.2	0.5
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.3	0.3	-0.1	-0.1	-0.2	0.2	0.2	0.1	-0.0	-1.1	0.9	0.2	-0.1	0.1
Forced vital capacity (FVC), Best measure	0.1	0.5	1.4	-0.4	1.2	0.8	1.0	0.9	0.6	0.8	-0.7	-0.0	-0.3	0.7	0.7	0.2
Average weekly beer plus cider intake	0.1	0.2	0.8	-0.3	-0.2	0.1	-0.4	-0.0	-0.2	-0.9	-0.0	0.4	-0.5	-0.8	-0.4	-0.7
Myopia	0.1	0.1	0.7	0.1	0.2	0.2	0.1	0.9	-0.2	0.0	-0.3	0.1	-0.1	0.6	0.3	0.5

Hub : Genes

ZNF229

Models

Trait associations