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chr19:18,740,208-20,451,172

Best TWAS P=8.26e-14 · Best GWAS P=9.49e-18 conditioned to 7.22e-06

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells Transformed fibroblasts	ATP13A1	0.14	0.06	lasso	5	0.05	2.2e-04	-7.4	-7.5	8.3e-14	0.93	0.19	0.56	TRUE
2	GTEx	Cells Transformed fibroblasts	GATAD2A	0.07	0.00	lasso	4	0.00	8.1e-01	-5.0	-6.8	7.5e-12	0.72	0.07	0.31	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	ATP13A1	0.10	0.07	lasso	5	0.06	1.3e-08	-6.2	6.1	1.2e-09	-0.78	0.14	0.85	FALSE
5	GTEx	Whole Blood	GATAD2A	0.06	0.02	lasso	9	0.03	1.7e-03	-5.0	-5.4	6.4e-08	0.63	0.36	0.53	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	KIAA0892	0.04	0.04	blup	43	0.02	4.1e-03	-5.2	5.3	9.8e-08	-0.43	0.53	0.05	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HAPLN4	0.05	0.07	lasso	2	0.06	1.1e-07	-5.2	-5.3	9.9e-08	0.48	0.99	0.01	FALSE
9	The Cancer Genome Atlas	Thyroid Carcinoma	HAPLN4	0.08	0.06	blup	37	0.09	1.8e-09	-5.2	-5.3	1.2e-07	0.33	1.00	0.00	FALSE
4	GTEx	Spleen	ATP13A1	0.16	0.01	lasso	5	0.02	9.7e-02	-5.0	-5.2	1.6e-07	0.35	0.08	0.07	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TM6SF2	0.04	0.03	blup	35	0.03	2.5e-04	-4.2	-5.2	1.9e-07	0.76	0.22	0.44	FALSE
3	GTEx	Muscle Skeletal	MAU2	0.09	0.04	lasso	4	0.05	5.1e-06	-4.1	5.2	2.3e-07	-0.59	0.99	0.01	FALSE