[Hub]/) : Traits : BMI : ← →

chr10:98,395,083-100,704,597

Best TWAS P=8.31e-17 · Best GWAS P=1.63e-22 conditioned to 3.48e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CRTAC1 0.06 0.04 lasso 2 0.05 3.6e-07 5.53 -8.2 1.7e-16 0.63 0.43 0.54 FALSE
2 CommonMind Brain Pre-frontal Cortex FRAT2 0.05 0.04 lasso 2 0.04 2.3e-05 5.04 -5.4 6.4e-08 0.05 0.06 0.94 FALSE
3 CommonMind Brain Pre-frontal Cortex GOLGA7B 0.07 0.00 enet 23 0.04 1.3e-05 0.11 -6.5 8.1e-11 0.46 0.59 0.04 TRUE
4 GTEx Nerve Tibial R3HCC1L 0.06 0.07 enet 8 0.05 1.1e-04 -8.19 -8.3 8.3e-17 0.37 0.78 0.01 TRUE
5 GTEx Skin Sun Exposed Lower leg R3HCC1L 0.10 0.05 enet 14 0.05 3.4e-05 4.74 -6.6 4.3e-11 0.32 0.94 0.01 FALSE
6 GTEx Testis FRAT2 0.19 0.10 lasso 3 0.13 1.7e-06 5.54 -5.5 3.7e-08 0.06 0.03 0.97 FALSE
7 ROSMAP Brain Pre-frontal Cortex CRTAC1 0.09 0.06 lasso 3 0.05 3.4e-07 5.53 -5.5 2.8e-08 0.38 0.98 0.00 FALSE
8 ROSMAP Brain Pre-frontal Cortex FRAT2 0.06 0.07 lasso 4 0.07 3.0e-09 5.43 -5.5 4.1e-08 0.05 0.04 0.96 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma SLIT1 0.04 0.04 enet 15 0.04 1.1e-08 5.85 5.8 6.1e-09 -0.07 0.00 1.00 TRUE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FRAT1 0.06 0.01 blup 36 0.02 1.3e-03 -3.50 -5.4 6.9e-08 0.01 0.02 0.70 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLIT1 0.12 0.12 lasso 1 0.11 1.6e-12 5.45 5.5 4.9e-08 -0.07 0.02 0.98 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LOXL4 0.08 0.00 blup 51 0.02 9.4e-03 -4.82 -6.9 4.1e-12 0.16 0.01 0.45 FALSE