[Hub]/) : Traits : BMI : ← →

chr1:15,202,204-18,027,554

Best TWAS P=6.68e-13 · Best GWAS P=1.56e-10 conditioned to 0.000671

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AGMAT	0.21	0.25	lasso	5	0.27	1.3e-32	-4.80	-5.2	2.3e-07	0.09	0.01	0.98	FALSE
2	GTEx	Adipose Subcutaneous	MST1P2	0.12	0.01	enet	20	0.04	2.1e-04	3.21	-5.5	4.8e-08	-0.40	0.07	0.21	FALSE
3	GTEx	Adipose Visceral Omentum	MST1L	0.15	0.08	enet	21	0.11	1.7e-06	-5.02	5.2	1.9e-07	0.75	0.03	0.97	FALSE
4	GTEx	Artery Coronary	RP11-108M9.4	0.23	-0.01	enet	13	0.01	1.1e-01	3.21	5.2	1.7e-07	0.51	0.11	0.29	FALSE
5	GTEx	Brain Cerebellum	MST1L	0.21	0.13	lasso	2	0.09	1.7e-03	-5.83	5.3	8.9e-08	0.67	0.03	0.81	FALSE
6	GTEx	Brain Hippocampus	MST1P2	0.41	0.07	lasso	6	0.19	3.4e-05	-0.84	-5.4	6.5e-08	-0.55	0.05	0.49	FALSE
7	GTEx	Breast Mammary Tissue (Male)	RP11-108M9.4	0.10	-0.01	enet	5	-0.01	5.6e-01	3.41	5.3	1.3e-07	0.00	0.03	0.08	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	MST1L	0.31	0.10	lasso	6	0.14	2.2e-05	6.40	5.7	1.1e-08	0.92	0.00	1.00	FALSE
9	GTEx	Esophagus Mucosa	MST1P2	0.32	0.06	enet	22	0.12	3.3e-08	5.28	-5.8	8.0e-09	-0.54	0.08	0.90	FALSE
10	GTEx	Esophagus Mucosa	RP1-37C10.3	0.10	0.10	enet	4	0.07	3.8e-05	5.28	-5.3	1.5e-07	-0.64	0.03	0.97	FALSE
11	GTEx	Heart Atrial Appendage	MST1P2	0.20	0.09	lasso	4	0.09	6.7e-05	5.28	-5.8	6.1e-09	-0.73	0.07	0.88	FALSE
12	GTEx	Liver	MST1P2	0.20	0.14	lasso	4	0.10	7.6e-04	-5.83	-6.7	2.9e-11	-0.88	0.01	0.96	FALSE
13	GTEx	Lung	MST1P2	0.20	0.10	enet	26	0.10	5.0e-08	-5.02	-5.5	4.4e-08	-0.69	0.05	0.95	FALSE
14	GTEx	Skin Sun Exposed Lower leg	MST1P2	0.24	0.00	enet	29	0.13	8.8e-11	-5.02	-7.2	6.7e-13	-0.57	0.04	0.96	TRUE
15	GTEx	Testis	CROCC	0.18	0.03	lasso	4	0.04	1.0e-02	-5.83	6.0	1.4e-09	0.74	0.05	0.57	FALSE
16	GTEx	Testis	MST1L	0.45	0.20	enet	34	0.25	2.5e-11	6.40	5.8	6.2e-09	0.85	0.00	1.00	FALSE
17	GTEx	Testis	RP11-108M9.5	0.25	0.01	enet	38	0.09	6.1e-05	-5.19	5.3	1.0e-07	0.36	0.07	0.33	FALSE
18	GTEx	Thyroid	MST1P2	0.18	0.11	lasso	9	0.13	2.7e-10	-5.02	-5.4	8.4e-08	-0.75	0.08	0.92	FALSE
19	GTEx	Whole Blood	MST1L	0.08	0.02	enet	12	0.04	6.3e-05	2.35	5.5	3.6e-08	0.79	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	ATP13A2	0.05	0.00	enet	1	0.01	1.6e-02	6.13	-6.1	8.8e-10	-0.80	0.00	0.64	FALSE
21	The Cancer Genome Atlas	Colon Adenocarcinoma	ATP13A2	0.11	0.04	blup	54	0.08	3.4e-05	-5.02	-5.5	4.9e-08	-0.68	0.04	0.87	FALSE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	CASP9	0.15	0.10	blup	52	0.10	1.2e-06	-4.93	-5.3	1.2e-07	0.09	0.01	0.98	TRUE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	MFAP2	0.12	0.06	blup	38	0.07	4.3e-05	4.62	-5.8	8.2e-09	-0.92	0.00	1.00	FALSE
24	The Cancer Genome Atlas	Colon Adenocarcinoma	MST1P9	0.08	0.00	blup	38	0.01	5.4e-02	-5.02	5.3	1.2e-07	0.48	0.01	0.25	FALSE
25	The Cancer Genome Atlas	Glioblastoma Multiforme	AGMAT	0.10	0.08	lasso	3	0.03	3.3e-02	-4.87	-5.1	2.8e-07	0.09	0.00	0.48	FALSE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ATP13A2	0.05	0.08	enet	5	0.07	2.1e-08	5.28	-5.5	4.9e-08	-0.75	0.14	0.86	FALSE
27	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MST1P9	0.15	0.13	enet	15	0.13	1.5e-14	5.28	5.7	1.0e-08	0.74	0.06	0.94	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MFAP2	0.17	0.22	enet	10	0.23	6.8e-26	6.13	-5.5	2.8e-08	-0.79	0.01	0.99	FALSE
29	The Cancer Genome Atlas	Brain Lower Grade Glioma	MST1P9	0.15	0.13	enet	14	0.17	6.2e-19	6.13	5.1	3.1e-07	0.77	0.01	0.99	FALSE
30	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MST1P9	0.04	0.02	lasso	5	0.02	1.0e-03	6.40	6.0	1.5e-09	0.93	0.00	0.99	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	MFAP2	0.06	0.04	blup	38	0.05	5.2e-06	-5.02	-5.2	2.0e-07	-0.85	0.01	0.99	FALSE
32	The Cancer Genome Atlas	Soft Tissue Sarcoma	SDHB	0.06	0.03	blup	99	0.02	2.1e-02	6.40	-5.4	5.8e-08	-0.86	0.00	0.92	FALSE