[Hub]/) : Traits : BMI :

chr1:15,202,204-18,027,554

Best TWAS P=6.68e-13 · Best GWAS P=1.56e-10 conditioned to 0.000671

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AGMAT 0.21 0.25 lasso 5 0.27 1.3e-32 -4.80 -5.2 2.3e-07 0.09 0.01 0.98 FALSE
2 GTEx Adipose Subcutaneous MST1P2 0.12 0.01 enet 20 0.04 2.1e-04 3.21 -5.5 4.8e-08 -0.40 0.07 0.21 FALSE
3 GTEx Adipose Visceral Omentum MST1L 0.15 0.08 enet 21 0.11 1.7e-06 -5.02 5.2 1.9e-07 0.75 0.03 0.97 FALSE
4 GTEx Artery Coronary RP11-108M9.4 0.23 -0.01 enet 13 0.01 1.1e-01 3.21 5.2 1.7e-07 0.51 0.11 0.29 FALSE
5 GTEx Brain Cerebellum MST1L 0.21 0.13 lasso 2 0.09 1.7e-03 -5.83 5.3 8.9e-08 0.67 0.03 0.81 FALSE
6 GTEx Brain Hippocampus MST1P2 0.41 0.07 lasso 6 0.19 3.4e-05 -0.84 -5.4 6.5e-08 -0.55 0.05 0.49 FALSE
7 GTEx Breast Mammary Tissue (Male) RP11-108M9.4 0.10 -0.01 enet 5 -0.01 5.6e-01 3.41 5.3 1.3e-07 0.00 0.03 0.08 FALSE
8 GTEx Cells EBV-transformed lymphocytes MST1L 0.31 0.10 lasso 6 0.14 2.2e-05 6.40 5.7 1.1e-08 0.92 0.00 1.00 FALSE
9 GTEx Esophagus Mucosa MST1P2 0.32 0.06 enet 22 0.12 3.3e-08 5.28 -5.8 8.0e-09 -0.54 0.08 0.90 FALSE
10 GTEx Esophagus Mucosa RP1-37C10.3 0.10 0.10 enet 4 0.07 3.8e-05 5.28 -5.3 1.5e-07 -0.64 0.03 0.97 FALSE
11 GTEx Heart Atrial Appendage MST1P2 0.20 0.09 lasso 4 0.09 6.7e-05 5.28 -5.8 6.1e-09 -0.73 0.07 0.88 FALSE
12 GTEx Liver MST1P2 0.20 0.14 lasso 4 0.10 7.6e-04 -5.83 -6.7 2.9e-11 -0.88 0.01 0.96 FALSE
13 GTEx Lung MST1P2 0.20 0.10 enet 26 0.10 5.0e-08 -5.02 -5.5 4.4e-08 -0.69 0.05 0.95 FALSE
14 GTEx Skin Sun Exposed Lower leg MST1P2 0.24 0.00 enet 29 0.13 8.8e-11 -5.02 -7.2 6.7e-13 -0.57 0.04 0.96 TRUE
15 GTEx Testis CROCC 0.18 0.03 lasso 4 0.04 1.0e-02 -5.83 6.0 1.4e-09 0.74 0.05 0.57 FALSE
16 GTEx Testis MST1L 0.45 0.20 enet 34 0.25 2.5e-11 6.40 5.8 6.2e-09 0.85 0.00 1.00 FALSE
17 GTEx Testis RP11-108M9.5 0.25 0.01 enet 38 0.09 6.1e-05 -5.19 5.3 1.0e-07 0.36 0.07 0.33 FALSE
18 GTEx Thyroid MST1P2 0.18 0.11 lasso 9 0.13 2.7e-10 -5.02 -5.4 8.4e-08 -0.75 0.08 0.92 FALSE
19 GTEx Whole Blood MST1L 0.08 0.02 enet 12 0.04 6.3e-05 2.35 5.5 3.6e-08 0.79 0.01 0.99 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma ATP13A2 0.05 0.00 enet 1 0.01 1.6e-02 6.13 -6.1 8.8e-10 -0.80 0.00 0.64 FALSE
21 The Cancer Genome Atlas Colon Adenocarcinoma ATP13A2 0.11 0.04 blup 54 0.08 3.4e-05 -5.02 -5.5 4.9e-08 -0.68 0.04 0.87 FALSE
22 The Cancer Genome Atlas Colon Adenocarcinoma CASP9 0.15 0.10 blup 52 0.10 1.2e-06 -4.93 -5.3 1.2e-07 0.09 0.01 0.98 TRUE
23 The Cancer Genome Atlas Colon Adenocarcinoma MFAP2 0.12 0.06 blup 38 0.07 4.3e-05 4.62 -5.8 8.2e-09 -0.92 0.00 1.00 FALSE
24 The Cancer Genome Atlas Colon Adenocarcinoma MST1P9 0.08 0.00 blup 38 0.01 5.4e-02 -5.02 5.3 1.2e-07 0.48 0.01 0.25 FALSE
25 The Cancer Genome Atlas Glioblastoma Multiforme AGMAT 0.10 0.08 lasso 3 0.03 3.3e-02 -4.87 -5.1 2.8e-07 0.09 0.00 0.48 FALSE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ATP13A2 0.05 0.08 enet 5 0.07 2.1e-08 5.28 -5.5 4.9e-08 -0.75 0.14 0.86 FALSE
27 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MST1P9 0.15 0.13 enet 15 0.13 1.5e-14 5.28 5.7 1.0e-08 0.74 0.06 0.94 FALSE
28 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MFAP2 0.17 0.22 enet 10 0.23 6.8e-26 6.13 -5.5 2.8e-08 -0.79 0.01 0.99 FALSE
29 The Cancer Genome Atlas Brain Lower Grade Glioma MST1P9 0.15 0.13 enet 14 0.17 6.2e-19 6.13 5.1 3.1e-07 0.77 0.01 0.99 FALSE
30 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MST1P9 0.04 0.02 lasso 5 0.02 1.0e-03 6.40 6.0 1.5e-09 0.93 0.00 0.99 FALSE
31 The Cancer Genome Atlas Prostate Adenocarcinoma MFAP2 0.06 0.04 blup 38 0.05 5.2e-06 -5.02 -5.2 2.0e-07 -0.85 0.01 0.99 FALSE
32 The Cancer Genome Atlas Soft Tissue Sarcoma SDHB 0.06 0.03 blup 99 0.02 2.1e-02 6.40 -5.4 5.8e-08 -0.86 0.00 0.92 FALSE