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chr6:115,569,351-118,726,243

Best TWAS P=3.52e-38 · Best GWAS P=4.7e-56 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FRK	0.06	0.06	lasso	2	0.05	6.1e-07	8.3	8.2	3.5e-16	-0.03	0.96	0.01	FALSE
2	CommonMind	Brain Pre-frontal Cortex	GOPC	0.12	0.11	lasso	7	0.09	2.2e-11	9.6	10.0	1.6e-23	0.10	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	TSPYL1	0.13	0.07	lasso	2	0.05	6.0e-05	-4.1	-8.1	4.9e-16	0.04	0.34	0.28	TRUE
4	GTEx	Adipose Subcutaneous	RP1-93H18.7	0.11	0.08	lasso	3	0.08	8.1e-07	-10.7	-10.9	1.0e-27	0.02	0.98	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	FAM26F	0.15	0.05	enet	17	0.11	3.9e-06	6.6	6.7	1.5e-11	-0.04	0.26	0.57	FALSE
6	GTEx	Artery Aorta	GOPC	0.11	0.09	enet	13	0.12	4.7e-07	9.3	-9.6	1.3e-21	-0.07	0.92	0.00	FALSE
7	GTEx	Artery Aorta	NT5DC1	0.23	0.08	lasso	10	0.08	4.6e-05	8.9	11.5	7.9e-31	0.05	0.84	0.03	FALSE
8	GTEx	Artery Aorta	RP3-486I3.4	0.10	0.03	enet	23	0.03	6.1e-03	9.8	8.2	3.4e-16	0.02	0.12	0.57	FALSE
9	GTEx	Artery Tibial	GOPC	0.11	0.08	lasso	4	0.09	9.0e-08	9.7	-10.9	8.5e-28	-0.08	0.99	0.00	TRUE
10	GTEx	Artery Tibial	FRK	0.16	0.10	lasso	9	0.13	1.4e-10	9.8	9.8	1.2e-22	0.07	1.00	0.00	FALSE
11	GTEx	Artery Tibial	NT5DC1	0.21	0.07	enet	31	0.13	2.5e-10	9.8	7.0	3.0e-12	0.09	1.00	0.00	FALSE
12	GTEx	Artery Tibial	RP3-486I3.5	0.10	0.00	enet	18	0.05	9.7e-05	-5.7	6.6	4.2e-11	0.01	0.12	0.08	FALSE
13	GTEx	Breast Mammary Tissue	DCBLD1	0.10	0.02	lasso	4	0.03	1.1e-02	9.4	-8.9	3.8e-19	-0.05	0.16	0.05	FALSE
14	GTEx	Breast Mammary Tissue (Male)	GOPC	0.05	0.03	enet	7	0.05	2.2e-02	1.7	-6.7	1.7e-11	-0.04	0.05	0.06	FALSE
15	GTEx	Breast Mammary Tissue (Female)	RP3-486I3.4	0.11	0.00	lasso	3	0.00	4.3e-01	-7.6	7.6	2.8e-14	0.04	0.04	0.05	FALSE
16	GTEx	Cells EBV-transformed lymphocytes	FRK	0.12	0.07	enet	12	0.09	8.1e-04	-7.8	-11.1	1.8e-28	-0.09	0.30	0.17	FALSE
17	GTEx	Cells EBV-transformed lymphocytes	DSE	0.13	0.09	lasso	4	0.03	3.0e-02	11.0	12.6	2.3e-36	0.02	0.10	0.60	FALSE
18	GTEx	Cells EBV-transformed lymphocytes	FAM26F	0.34	0.10	enet	32	0.32	5.8e-11	10.0	12.2	4.6e-34	0.00	0.03	0.97	FALSE
19	GTEx	Cells Transformed fibroblasts	FRK	0.12	0.18	lasso	5	0.16	8.0e-12	9.7	-9.9	6.0e-23	-0.12	1.00	0.00	FALSE
20	GTEx	Cells Transformed fibroblasts	DSE	0.07	0.01	enet	7	0.01	4.1e-02	-11.0	-12.9	3.5e-38	0.05	0.23	0.62	TRUE
21	GTEx	Cells Transformed fibroblasts	NT5DC1	0.07	0.03	enet	9	0.05	9.8e-05	7.9	-11.7	9.0e-32	-0.07	0.03	0.91	TRUE
22	GTEx	Cells Transformed fibroblasts	FAM26F	0.29	0.19	enet	26	0.23	1.9e-17	-9.5	9.8	7.8e-23	-0.02	1.00	0.00	FALSE
23	GTEx	Cells Transformed fibroblasts	RP1-93H18.7	0.08	0.06	enet	8	0.07	3.9e-06	-10.6	-12.3	8.4e-35	0.05	0.86	0.12	FALSE
24	GTEx	Colon Transverse	FRK	0.14	0.16	lasso	4	0.14	5.7e-07	9.7	-9.5	2.4e-21	-0.10	0.98	0.00	FALSE
25	GTEx	Esophagus Gastroesophageal Junction	FAM26F	0.10	0.13	lasso	2	0.06	2.3e-03	6.6	6.8	1.2e-11	0.05	0.20	0.21	FALSE
26	GTEx	Esophagus Gastroesophageal Junction	RP1-93H18.7	0.16	0.06	lasso	3	0.05	5.3e-03	-9.5	-10.2	1.8e-24	0.03	0.22	0.10	FALSE
27	GTEx	Esophagus Mucosa	NT5DC1	0.09	0.08	lasso	2	0.05	2.9e-04	9.7	-9.7	3.1e-22	-0.12	0.42	0.19	FALSE
28	GTEx	Esophagus Muscularis	RP1-93H18.7	0.17	0.02	lasso	4	0.03	5.0e-03	-11.0	-9.0	1.5e-19	-0.02	0.16	0.17	FALSE
29	GTEx	Lung	RP1-93H18.7	0.06	0.07	lasso	4	0.04	4.4e-04	-9.8	-10.0	2.1e-23	0.03	0.56	0.04	TRUE
30	GTEx	Muscle Skeletal	FRK	0.10	0.05	enet	18	0.08	1.4e-08	9.7	-9.2	3.2e-20	-0.12	0.37	0.62	FALSE
31	GTEx	Muscle Skeletal	NUS1	0.09	0.04	enet	14	0.08	1.1e-08	-6.6	-7.1	1.5e-12	0.08	0.94	0.00	FALSE
32	GTEx	Muscle Skeletal	NT5DC1	0.16	0.17	lasso	10	0.17	1.1e-16	9.7	-9.4	4.7e-21	-0.09	1.00	0.00	FALSE
33	GTEx	Muscle Skeletal	RP3-486I3.5	0.08	0.04	enet	12	0.03	2.8e-04	9.7	-8.3	9.1e-17	-0.09	0.97	0.00	TRUE
34	GTEx	Nerve Tibial	GOPC	0.12	0.06	enet	17	0.06	3.7e-05	10.0	-10.5	7.6e-26	-0.04	0.99	0.00	FALSE
35	GTEx	Nerve Tibial	DCBLD1	0.13	0.00	enet	26	0.03	5.3e-03	4.1	-6.1	1.1e-09	-0.11	0.10	0.05	FALSE
36	GTEx	Nerve Tibial	NT5DC1	0.16	0.12	lasso	4	0.13	2.1e-09	9.7	-6.8	9.5e-12	-0.14	1.00	0.00	FALSE
37	GTEx	Nerve Tibial	RP1-93H18.7	0.14	0.08	lasso	6	0.08	1.7e-06	-9.4	-9.3	2.1e-20	0.13	0.90	0.01	FALSE
38	GTEx	Pancreas	FRK	0.09	0.13	lasso	5	0.09	1.2e-04	9.7	-9.7	2.6e-22	-0.11	0.73	0.02	FALSE
39	GTEx	Pancreas	NUS1	0.27	0.28	enet	22	0.25	7.6e-11	-6.2	-6.8	1.0e-11	0.07	1.00	0.00	FALSE
40	GTEx	Skin Sun Exposed Lower leg	RP1-93H18.7	0.07	0.04	enet	5	0.03	1.1e-03	-10.7	-10.3	7.5e-25	0.03	0.45	0.04	FALSE
41	GTEx	Stomach	FRK	0.12	0.02	lasso	5	0.04	8.0e-03	-2.5	-7.0	2.6e-12	-0.03	0.38	0.10	FALSE
42	GTEx	Testis	DSE	0.36	0.41	lasso	6	0.39	1.1e-18	6.3	6.8	1.1e-11	0.01	1.00	0.00	TRUE
43	GTEx	Testis	RSPH4A	0.38	0.14	enet	26	0.21	1.4e-09	-3.9	-5.5	3.5e-08	-0.11	0.89	0.03	FALSE
44	GTEx	Testis	TSPYL4	0.09	0.02	lasso	6	0.03	1.6e-02	-2.9	7.1	1.0e-12	-0.01	0.15	0.20	TRUE
45	GTEx	Testis	FAM26F	0.23	0.10	lasso	8	0.22	3.0e-10	-8.5	11.0	3.0e-28	-0.04	0.12	0.86	FALSE
46	GTEx	Thyroid	GOPC	0.11	0.02	enet	23	0.02	1.6e-02	9.6	-9.9	2.8e-23	0.18	0.50	0.03	FALSE
47	GTEx	Thyroid	FRK	0.08	0.10	lasso	3	0.09	4.6e-07	9.7	-9.4	4.5e-21	-0.12	0.97	0.00	FALSE
48	GTEx	Thyroid	TSPYL1	0.07	0.04	lasso	2	0.00	1.5e-01	9.6	-9.8	6.6e-23	-0.04	0.08	0.19	FALSE
49	GTEx	Whole Blood	DSE	0.09	0.05	lasso	5	0.04	1.8e-04	-10.6	-10.2	1.5e-24	0.07	0.94	0.02	FALSE
50	GTEx	Whole Blood	DCBLD1	0.16	0.09	lasso	7	0.09	7.7e-09	-2.3	6.0	2.2e-09	0.02	1.00	0.00	FALSE
51	GTEx	Whole Blood	NT5DC1	0.09	0.00	enet	21	0.02	1.1e-02	5.4	-5.9	4.6e-09	-0.12	0.20	0.14	FALSE
52	GTEx	Whole Blood	RP1-93H18.7	0.19	0.17	lasso	3	0.16	3.1e-14	-9.8	-10.8	2.7e-27	0.04	1.00	0.00	FALSE
53	METSIM	Adipose	FRK	0.15	0.10	bslmm	440	0.12	7.9e-18	9.6	-7.4	1.2e-13	-0.14	1.00	0.00	FALSE
54	METSIM	Adipose	NT5DC1	0.11	0.08	lasso	8	0.09	8.2e-14	9.7	-9.6	7.2e-22	-0.10	1.00	0.00	FALSE
55	METSIM	Adipose	TSPYL1	0.13	0.06	blup	370	0.08	3.7e-12	6.1	-8.4	5.0e-17	-0.03	0.97	0.03	FALSE
56	NTR	Blood	DCBLD1	0.02	0.02	lasso	4	0.02	1.1e-07	-5.8	5.7	1.2e-08	-0.04	0.99	0.00	FALSE
57	NTR	Blood	DSE	0.04	0.02	bslmm	437	0.02	1.7e-08	-10.7	-11.6	5.9e-31	-0.03	0.19	0.81	FALSE
58	ROSMAP	Brain Pre-frontal Cortex	GOPC	0.13	0.16	enet	21	0.16	1.5e-19	10.0	10.8	3.6e-27	0.07	1.00	0.00	FALSE
59	ROSMAP	Brain Pre-frontal Cortex	DCBLD1	0.13	0.07	blup	444	0.09	5.8e-12	10.0	-5.7	9.3e-09	-0.11	1.00	0.00	FALSE
60	ROSMAP	Brain Pre-frontal Cortex	FAM26F	0.15	0.10	enet	13	0.13	2.6e-16	5.0	8.2	1.8e-16	-0.01	1.00	0.00	FALSE
61	YFS	Blood	DCBLD1	0.13	0.13	enet	26	0.14	2.2e-44	-5.8	5.1	2.7e-07	-0.02	1.00	0.00	FALSE
62	YFS	Blood	NT5DC1	0.07	0.03	bslmm	431	0.04	6.4e-13	7.5	-7.9	3.1e-15	0.04	1.00	0.00	FALSE
63	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FAM26F	0.09	0.03	blup	48	0.06	6.0e-06	5.2	6.2	7.0e-10	-0.05	0.44	0.02	FALSE
64	The Cancer Genome Atlas	Breast Invasive Carcinoma	GOPC	0.02	0.02	lasso	1	0.02	2.1e-04	9.3	-9.3	1.6e-20	-0.10	0.19	0.69	FALSE
65	The Cancer Genome Atlas	Breast Invasive Carcinoma	RFX6	0.02	0.01	lasso	3	0.01	4.2e-03	-9.0	-8.2	2.2e-16	0.26	0.01	0.92	TRUE
66	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FAM26F	0.20	0.08	blup	48	0.10	1.3e-05	7.6	7.8	4.7e-15	0.00	0.17	0.53	FALSE
67	The Cancer Genome Atlas	Colon Adenocarcinoma	FRK	0.10	0.10	lasso	7	0.09	4.2e-06	9.7	-9.9	3.8e-23	-0.08	0.09	0.90	TRUE
68	The Cancer Genome Atlas	Glioblastoma Multiforme	FRK	0.13	0.01	blup	94	0.05	1.5e-02	-7.7	-10.9	1.3e-27	-0.04	0.02	0.30	FALSE
69	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FRK	0.08	0.01	blup	94	0.01	4.8e-02	11.2	-8.3	1.1e-16	-0.07	0.01	0.80	FALSE
70	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FAM26F	0.40	0.20	lasso	8	0.25	2.3e-14	9.7	8.5	2.6e-17	-0.02	1.00	0.00	FALSE
71	The Cancer Genome Atlas	Prostate Adenocarcinoma	FRK	0.10	0.08	lasso	1	0.05	3.2e-06	9.6	-9.7	5.1e-22	-0.11	0.57	0.42	FALSE
72	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUS1	0.07	0.01	blup	45	0.03	1.8e-04	-6.2	-5.8	6.0e-09	0.14	0.12	0.03	TRUE
73	The Cancer Genome Atlas	Stomach Adenocarcinoma	FRK	0.03	0.00	blup	94	0.03	4.6e-03	9.7	-10.1	5.9e-24	-0.08	0.06	0.45	FALSE
74	The Cancer Genome Atlas	Thyroid Carcinoma	DSE	0.05	0.01	blup	112	0.04	1.6e-04	-3.8	-9.6	7.1e-22	0.03	0.04	0.05	FALSE
75	The Cancer Genome Atlas	Thyroid Carcinoma	FRK	0.08	0.09	lasso	2	0.09	5.0e-09	9.7	-9.7	4.1e-22	-0.10	0.84	0.16	FALSE