TWAS hub - TSPYL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1290	0.0470	1.1e-03	0.070	NA	0.042	NA	0.050	2.4e-06	NA	2.2e-04	NA	6.0e-05
2	GTEx	Artery Aorta	0.2360	0.0610	1.9e-06	0.139	NA	0.154	NA	0.142	4.3e-08	NA	7.2e-09	NA	3.0e-08
3	GTEx	Artery Tibial	0.1190	0.0428	3.7e-04	0.081	NA	0.045	NA	0.068	6.3e-07	NA	2.0e-04	NA	5.2e-06
4	GTEx	Cells Transformed fibroblasts	0.2180	0.0590	1.8e-06	0.134	NA	0.116	NA	0.129	3.2e-10	NA	5.6e-09	NA	6.3e-10
5	GTEx	Esophagus Mucosa	0.1570	0.0450	8.1e-06	0.123	NA	0.088	NA	0.109	1.4e-08	NA	1.6e-06	NA	9.8e-08
6	GTEx	Esophagus Muscularis	0.1650	0.0550	2.0e-04	0.148	NA	0.104	NA	0.122	2.6e-09	NA	7.6e-07	NA	7.9e-08
7	GTEx	Muscle Skeletal	0.1962	0.0645	7.9e-06	-0.003	NA	0.022	NA	0.002	8.1e-01	NA	2.9e-03	NA	2.0e-01
8	GTEx	Testis	0.1960	0.0610	4.6e-04	0.007	NA	0.068	NA	0.035	1.5e-01	NA	6.1e-04	NA	1.1e-02
9	GTEx	Thyroid	0.0690	0.0350	9.1e-03	0.041	NA	0.001	NA	0.004	4.1e-04	NA	2.9e-01	NA	1.5e-01
10	METSIM	Adipose	0.1264	0.0338	4.4e-10	0.061	0.081	0.072	0.081	0.073	1.6e-09	3.7e-12	6.8e-11	3.8e-12	4.9e-11
11	YFS	Blood	0.0208	0.0088	3.9e-04	0.002	0.008	0.001	0.008	0.002	5.7e-02	8.0e-04	1.4e-01	9.7e-04	6.8e-02
12	TCGA	Esophageal Carcinoma	0.1800	0.0890	8.9e-04	0.042	0.081	0.028	NA	0.045	1.7e-02	1.5e-03	4.5e-02	NA	1.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Ulcerative Colitis (UC)	4.4	8.2	17.2	3.1	2.5	2.7	3.5	3.3	3.4	2.5	4.1	2.3	1.0	2.6	2.1
Ulcerative Colitis	4.4	6.4	16.0	2.6	2.2	2.2	2.9	2.9	2.8	3.4	4.0	1.1	0.6	1.6	1.7
Illnesses of father: Heart disease	4.4	6.1	10.4	3.0	2.3	3.0	2.6	2.4	2.9	0.4	2.1	2.1	2.6	3.2	1.5
Medication: Ibuprofen	4.0	4.8	8.6	-1.7	-2.4	-2.0	-2.6	-2.8	-2.2	-0.4	-2.7	-0.7	-2.2	-2.1	-2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.7	7.9	17.8	1.6	3.4	2.9	3.6	3.6	2.9	-0.6	3.7	-0.4	1.1	2.2	4.2
Supplements: Vitamin C	3.6	4.3	9.1	-2.4	-1.6	-2.2	-1.7	-1.7	-2.5	-2.0	-0.1	-3.0	-2.4	-2.7	0.7
Peak expiratory flow (PEF)	3.3	7.6	14.9	3.1	3.0	3.0	2.7	2.6	3.1	1.9	1.5	2.5	3.9	3.2	1.7
Emphysema/chronic bronchitis	3.3	3.7	8.1	2.8	2.2	2.6	1.9	1.9	2.3	1.4	1.4	1.3	1.9	1.4	0.2
Major Depression (MDD)	3.2	3.9	6.7	2.5	1.2	2.0	2.3	2.1	2.3	2.1	1.4	2.6	1.5	1.7	1.2
Vitamin and mineral supplements	3.0	4.1	8.7	2.2	1.7	1.9	2.0	2.2	2.6	1.4	1.6	3.0	1.2	2.6	-0.1
Depression (self-reported)	3.0	3.6	12.5	2.5	0.4	1.6	1.5	1.4	2.1	1.6	-0.4	3.5	2.7	1.7	0.2
Medication: Ventolin 100micrograms inhaler	2.9	3.7	15.3	2.0	1.0	1.8	0.9	0.9	1.5	2.2	-0.5	2.8	3.9	1.8	-0.2
Ever had bowel cancer screening	2.7	3.2	7.3	2.7	0.9	1.9	2.4	2.1	2.3	1.1	2.5	0.9	0.7	0.8	1.1
Ever had prostate specific antigen (PSA) test	2.7	3.1	8.1	-2.2	-1.3	-1.6	-2.0	-1.9	-1.7	-0.0	-2.3	-1.1	-1.5	-0.7	-2.8
Myopia	2.7	3.9	16.2	0.6	3.2	1.8	1.9	2.0	1.0	-0.7	1.4	-1.5	0.3	1.7	4.0
Medication: Cholesterol lowering	2.6	4.0	14.4	1.4	1.6	1.6	1.0	0.6	1.3	2.4	-0.1	3.8	2.9	3.0	-0.4
Illnesses of father: None of the above (group 1)	2.6	3.2	6.0	-2.2	-1.5	-2.3	-2.0	-2.0	-2.3	-1.1	-0.8	-1.3	-2.4	-1.6	-0.8
Mean Putamen Volume	2.5	2.8	5.9	-1.9	-1.0	-1.5	-1.5	-1.6	-1.7	-1.0	-1.3	-2.0	-2.4	-2.4	-0.8
Medication: Amlodipine	2.5	3.5	8.4	1.7	2.0	1.8	1.1	1.1	1.6	2.5	0.4	2.6	2.9	2.0	-0.4
Alzheimer’s Disease (in father)	2.4	2.6	4.6	1.2	2.1	1.9	1.7	1.5	1.6	1.0	0.8	1.6	1.7	2.1	1.7
Time employed in main current job	2.4	2.7	6.3	-2.3	-1.3	-2.0	-1.6	-1.2	-2.0	-1.8	-0.2	-2.5	-1.8	-1.1	-0.2
Supplements: Zinc	2.3	2.5	6.1	-1.7	-1.1	-1.8	-2.3	-2.2	-2.5	-1.7	-1.0	-0.8	-1.1	-0.6	-0.5
Medication: Atorvastatin	2.3	2.9	5.7	1.4	2.4	2.0	1.8	1.3	1.4	-0.2	1.6	2.2	1.6	1.6	1.9
LDL Cholesterol	2.2	3.5	18.7	0.9	0.2	0.7	0.4	-0.1	0.8	3.4	-0.6	4.3	2.3	1.7	-0.5
Blood clot in the leg (DVT)	2.2	2.8	6.3	-1.4	-2.0	-1.7	-1.5	-1.4	-1.7	-0.2	0.0	-2.5	-2.2	-2.4	-0.7
Supplements: Calcium	2.2	2.4	5.6	-1.8	-0.8	-2.2	-2.2	-2.2	-2.4	-1.3	0.2	-0.6	-1.4	0.3	-0.7
Length of working week for main job	2.1	2.3	4.5	-1.8	-1.7	-1.6	-1.4	-1.7	-1.7	-0.4	-2.1	-1.1	-1.9	-1.1	-0.7
Supplements: Glucosamine	2.0	2.6	6.5	-1.4	-1.5	-1.4	-2.1	-2.3	-1.6	0.5	-2.3	0.2	0.1	-0.7	-2.6
Medication: Allopurinol	2.0	2.6	6.9	2.0	1.5	1.4	0.7	0.4	1.1	2.6	-0.5	2.5	2.4	1.4	-0.9
Fractured/broken bones in last 5 years	2.0	2.6	6.4	-2.5	-0.9	-2.0	-1.7	-1.5	-1.9	-0.3	-1.1	-2.5	-1.4	-0.6	-1.1
Deep venous thrombosis (DVT) (self-reported)	2.0	2.6	5.7	-1.3	-2.0	-1.7	-1.6	-1.6	-1.7	0.3	-0.3	-2.0	-1.9	-2.4	-1.1
Nervous feelings	1.9	3.6	10.1	3.2	0.3	1.9	1.8	1.7	2.3	1.9	0.5	2.3	2.6	1.3	0.1
Mouth/teeth dental problems: Dentures	1.9	3.2	12.0	-1.7	-1.3	-1.5	-1.2	-1.2	-1.6	-0.9	-1.0	-3.5	-2.1	-2.8	-0.9
Angina (self-reported)	1.9	2.5	6.4	1.7	2.2	2.1	1.5	1.5	1.7	1.1	0.1	1.0	2.5	1.4	0.3
Eye problems/disorders: Cataract	1.9	2.2	3.8	-1.8	-1.7	-1.7	-2.0	-1.8	-1.8	0.1	-1.3	-0.0	-0.5	-0.5	-1.9
Tinnitus: Yes, now most or all of the time	1.9	2.2	4.6	-2.0	-1.2	-1.4	-1.4	-1.1	-1.6	-1.4	-1.2	-1.7	-2.1	-0.8	-1.4
Mouth/teeth dental problems	1.8	2.7	10.7	1.9	0.9	1.4	1.4	1.4	1.6	1.0	1.5	3.3	1.1	1.9	1.3
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	4.4	-0.9	-1.8	-1.4	-1.6	-1.8	-1.4	-0.5	-1.7	-0.4	-1.5	-2.0	-2.1
Gout (self-reported)	1.8	2.5	8.3	1.4	1.2	0.8	-0.1	-0.2	0.5	2.9	-0.8	2.9	2.1	1.4	-1.5
Miserableness	1.8	3.2	5.7	2.1	1.5	1.7	2.1	2.2	2.4	1.5	1.8	1.1	1.5	1.9	1.0
Respiratory disease	1.7	3.7	15.5	2.5	1.9	2.1	1.1	1.1	1.6	2.2	-0.1	2.1	3.9	1.0	-0.7
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	7.6	1.0	2.0	1.9	0.7	1.0	1.4	0.7	-0.6	1.3	2.8	2.1	0.5
Happiness	1.7	2.1	6.2	1.3	1.0	1.3	1.8	2.1	1.6	-0.5	1.8	0.2	0.3	0.7	2.5
Knee pain experienced in last month	1.7	2.6	6.7	-1.2	-1.5	-1.7	-1.9	-2.1	-1.5	1.5	-0.5	-1.3	-1.7	-0.4	-2.6
Angina	1.6	2.2	6.1	1.6	2.1	1.9	1.4	1.4	1.5	0.7	0.1	0.8	2.5	1.4	0.3
Sitting height	1.6	11.6	42.8	-6.5	0.3	-2.9	-1.8	-0.7	-3.0	-5.2	0.8	-4.7	-4.6	-0.3	1.9
Medication: Ramipril	1.6	2.0	4.5	-2.1	-1.4	-1.8	-1.4	-1.3	-1.7	-1.9	-0.5	0.2	-1.7	-0.5	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	12.2	0.0	2.9	1.6	2.5	2.8	1.8	-0.8	3.4	-2.5	-1.0	0.5	3.5
Medication: Omeprazole	1.6	1.9	3.6	1.4	1.3	1.1	1.4	1.6	1.5	1.9	1.6	0.5	0.8	0.9	1.8
High cholesterol (Self-reported)	1.6	2.8	9.0	-0.1	-0.8	-0.4	-1.3	-1.6	-0.5	2.4	-1.5	3.0	1.4	1.6	-2.6
Neuroticism (2016)	1.5	2.1	3.9	1.6	0.5	1.5	1.5	1.7	1.7	0.4	1.5	1.8	2.0	0.7	1.5
Cardiovascular Disease	1.5	4.8	18.7	1.9	1.2	1.9	0.9	0.6	1.4	1.9	-0.1	4.3	3.7	3.1	-0.5
Ever depressed for a whole week	1.5	1.9	4.5	2.1	1.1	1.4	1.7	1.6	1.8	1.2	1.5	0.6	0.1	1.0	1.1
Irritable Bowel Disease (IBD)	1.4	3.4	7.6	2.3	1.3	1.7	2.2	2.2	2.2	1.3	2.8	1.4	0.6	1.9	0.8
Breast Cancer	1.4	3.4	5.4	-1.9	-1.5	-2.2	-2.2	-2.2	-2.3	-0.3	-1.1	-2.1	-1.7	-1.6	-1.9
Triglycerides	1.4	2.3	5.6	1.0	0.4	1.3	0.3	0.2	0.9	1.9	-2.2	2.2	2.4	1.8	-1.3
Height	1.4	26.4	97.0	-8.1	0.1	-4.3	-3.1	-1.5	-4.2	-4.8	0.8	-9.8	-8.4	-3.4	0.1
Impedance of leg (left)	1.4	6.6	16.8	-3.0	-1.9	-2.7	-1.9	-1.8	-2.8	-1.2	-0.7	-3.9	-4.1	-3.3	-0.2
Standing height	1.4	14.3	42.4	-6.5	-0.7	-3.6	-2.7	-1.7	-3.5	-4.5	0.3	-5.8	-5.9	-2.1	0.0
Mineral and other dietary supplements	1.4	1.9	5.2	1.5	1.0	1.2	1.8	1.9	1.5	0.0	1.9	0.4	0.1	0.6	2.3
Vascular/heart problems diagnosed by doctor	1.4	4.0	11.8	-2.1	-0.8	-2.0	-1.8	-1.7	-2.0	-1.4	-0.6	-3.4	-3.0	-2.3	0.1
Impedance of leg (right)	1.3	6.2	13.8	-3.3	-1.7	-2.7	-2.0	-1.9	-2.8	-1.3	-1.0	-3.6	-3.7	-2.8	-0.4
Medication: Simvastatin	1.3	1.9	8.9	1.0	0.1	0.7	0.4	0.0	0.7	1.6	-0.8	3.0	2.3	1.8	-0.7
Hair/balding pattern: Pattern 3	1.3	1.9	5.1	-1.0	-1.7	-1.5	-1.6	-1.6	-1.4	0.3	-0.7	0.9	-0.8	-1.3	-2.2
Eye problems/disorders: None of the above	1.3	1.5	3.5	0.7	1.8	1.0	1.4	1.4	1.2	-0.6	1.9	-0.3	-0.5	1.1	1.7
Migraine (self-reported)	1.3	1.6	6.4	-1.4	-1.1	-1.0	-1.3	-1.0	-1.2	-2.5	-1.0	-1.2	-0.1	-1.0	-0.8
Comparative height size at age 10	1.3	7.0	22.8	-4.8	-0.2	-2.7	-2.4	-2.0	-2.8	-2.9	-0.6	-3.1	-3.9	-1.7	-0.3
Commuting to job workplace: Cycle	1.3	1.6	3.5	-1.3	-1.0	-1.2	-1.4	-1.4	-1.3	-1.9	-1.3	0.0	0.3	-0.9	-1.8
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	5.1	1.2	1.2	0.9	1.2	1.3	1.0	1.7	1.5	-0.2	0.6	0.0	2.3
Impedance of whole body	1.3	6.7	24.5	-3.2	-0.7	-2.1	-1.5	-1.4	-2.6	-2.3	-0.4	-5.0	-4.1	-2.6	0.8
Fluid intelligence score	1.2	2.5	5.6	1.2	0.9	1.5	1.5	1.5	1.6	-2.2	0.4	2.4	2.2	1.8	0.9
Prospective memory result	1.2	1.5	2.7	1.6	1.0	1.5	1.6	1.3	1.6	0.9	0.6	0.5	1.4	0.5	1.0
Osteoporosis (self-reported)	1.2	1.5	3.3	-1.6	-0.8	-1.5	-1.7	-1.4	-1.7	0.2	-0.1	-1.8	-1.0	-0.4	-0.8
Guilty feelings	1.2	1.8	3.5	-1.7	-0.9	-1.6	-1.9	-1.7	-1.5	0.7	-1.4	-0.3	-0.8	-0.4	-1.8
Primary Biliary Cirrhosis	1.1	1.5	3.9	-0.8	-1.7	-1.2	-0.9	-1.0	-1.1	-1.7	0.0	-1.5	-0.9	-2.0	-0.3
Lung FEV1/FVC ratio	1.1	5.7	17.7	-2.1	-1.4	-1.8	-0.4	-0.5	-1.7	-2.7	0.6	-4.2	-3.3	-3.6	2.3
Diabetes (father)	1.1	1.3	2.9	-1.6	-1.2	-1.2	-1.1	-1.2	-1.3	-0.4	-0.4	-0.3	-1.7	-1.3	-0.9
High blood pressure	1.1	3.1	11.5	1.8	0.5	1.6	1.4	1.3	1.6	1.0	0.5	3.4	2.7	2.3	-0.1
Impedance of arm (right)	1.1	4.9	20.9	-3.0	0.2	-1.5	-1.1	-0.9	-2.1	-2.1	0.1	-4.6	-3.5	-1.6	1.0
Impedance of arm (left)	1.1	5.0	26.2	-2.6	0.5	-1.1	-0.7	-0.4	-1.7	-2.4	0.1	-5.1	-3.4	-1.5	1.5
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	5.1	-1.2	-1.0	-1.2	-0.8	-0.4	-0.9	-2.3	0.3	-2.1	-2.0	-1.6	0.3
Forced vital capacity (FVC), Best measure	1.1	4.2	9.9	-0.1	3.1	1.6	2.2	2.6	1.8	-0.0	3.0	-2.1	-0.6	1.0	2.9
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	4.1	0.3	0.8	0.6	1.3	1.4	1.0	1.0	1.7	0.8	-0.6	0.9	2.0
Qualifications: nursing, teaching	1.1	1.7	7.1	-0.5	0.3	-0.3	-1.2	-1.6	-0.9	1.2	-2.4	0.2	0.3	-0.4	-2.7
Hearing aid user	1.1	1.3	2.6	1.6	0.8	1.1	1.4	1.4	1.3	0.7	1.3	0.5	1.3	0.4	1.1
Supplements: Fish oil (including cod liver oil)	1.1	1.4	2.2	-1.3	-0.6	-1.0	-1.4	-1.3	-1.3	-0.6	-1.3	-1.5	-0.9	-1.2	-1.4
Age started oral contraceptive pill	1.1	1.4	5.5	0.4	0.3	0.4	-0.8	-0.9	-0.2	1.1	-1.9	-0.1	1.5	1.3	-2.4
Depressed Affect (Nagel 2018)	1.0	2.2	5.5	1.2	0.8	1.5	2.0	2.3	2.0	0.9	2.2	-0.3	0.0	0.4	1.6
Allergy or Eczema	1.0	2.6	9.5	1.4	0.9	0.9	0.1	-0.2	0.9	3.1	-1.1	1.9	2.7	1.1	-1.9
Alcohol intake versus 10 years previously	1.0	1.5	3.2	-1.1	-1.7	-1.8	-0.9	-0.9	-1.1	-0.5	1.5	-0.9	-1.8	-0.8	-0.3
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	9.9	-0.3	2.5	1.2	2.0	2.2	1.4	-1.3	2.2	-1.8	-0.2	0.9	3.1
Chest pain or discomfort	1.0	1.4	7.2	1.5	-0.5	0.4	0.2	0.2	0.8	-0.6	0.0	2.7	1.8	1.0	-1.3
Risk taking	1.0	1.4	3.8	-1.2	-0.2	-1.1	-1.3	-1.2	-0.9	0.2	-0.9	-1.9	-1.3	-0.5	-1.9
Coronary Artery Disease (CAD)	0.9	1.1	3.6	0.8	1.2	1.4	0.7	0.4	0.9	0.7	-0.7	1.4	1.9	0.8	0.9
HbA1C	0.9	1.0	3.6	-0.0	1.9	1.3	0.4	0.2	0.7	1.1	-0.6	1.0	1.5	1.2	-0.0
Lung FVC	0.9	4.5	8.8	1.8	3.0	2.4	2.4	2.1	2.5	2.4	1.5	0.8	2.0	2.3	1.4
Ever had hysterectomy (womb removed)	0.9	1.0	2.1	1.4	-0.2	0.9	1.3	1.1	1.1	0.1	1.1	-1.4	-0.3	-0.6	1.1
Average weekly fortified wine intake	0.9	1.0	3.2	-0.1	-1.1	-0.6	-1.0	-1.0	-0.7	-0.3	-1.7	-0.8	-1.1	-0.9	-1.8
Maternal smoking around birth	0.9	1.4	6.1	-1.4	-0.3	-1.0	-0.1	-0.2	-0.8	-0.3	1.7	-1.1	-2.5	-1.2	0.8
Serious illness, injury or assault to yourself	0.9	1.1	4.9	0.2	-0.2	-0.2	-0.6	-0.7	-0.1	1.8	-1.9	0.5	-0.1	0.4	-2.2
Hayfever, allergic rhinitis or eczema	0.9	1.9	6.2	1.0	1.1	1.1	0.1	-0.1	0.9	1.8	-1.7	1.4	2.5	1.5	-1.6
Hearing difficulty/problems with background noise	0.9	1.4	6.5	1.7	0.9	0.9	0.1	0.5	1.1	2.5	0.1	0.6	1.3	1.0	-1.2
Hair/balding pattern: Pattern 2	0.9	1.1	2.0	1.4	0.9	1.1	1.1	1.0	1.2	0.0	0.7	0.2	1.4	1.4	1.3
Loud music exposure frequency	0.9	1.0	2.6	-0.9	-1.1	-1.6	-1.5	-1.4	-1.3	0.5	-0.7	-0.3	-0.6	-0.2	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	4.2	0.7	-0.0	0.5	-0.1	-0.1	0.6	-0.0	-2.0	1.2	1.7	1.1	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	4.5	-0.6	-0.2	-0.6	-0.7	-0.9	-0.8	-0.2	-0.4	-1.2	-2.1	-0.9	-1.6
Leg pain on walking	0.9	1.1	2.9	1.2	0.5	0.9	-0.1	-0.3	0.5	1.7	-0.8	1.5	1.2	1.6	-1.1
Hypertension (Self-reported)	0.9	2.4	9.2	1.6	0.3	1.4	1.3	1.1	1.4	0.9	0.7	3.0	2.3	2.0	0.0
Average weekly red wine intake	0.9	1.3	6.9	0.3	0.5	0.5	-0.3	-0.9	0.1	1.1	-1.1	2.6	1.2	0.6	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	4.1	0.7	-0.4	0.2	-0.1	0.1	0.4	2.0	-1.9	0.8	1.3	0.7	-1.0
Number of operations (self-reported)	0.9	1.3	5.9	0.4	2.4	1.1	0.5	0.3	0.8	1.2	0.8	0.0	0.7	2.1	-0.8
Heart disease (siblings)	0.9	1.1	3.3	1.5	0.8	1.4	1.0	0.6	1.0	-0.3	-0.7	1.4	1.8	0.6	0.5
Intelligence (Savage-Jansen 2018)	0.8	2.3	8.7	0.7	1.0	1.3	0.5	1.0	1.2	-0.6	-0.9	2.5	2.9	2.5	-0.1
Medication for hormone replacement therapy	0.8	0.8	3.8	-0.5	-1.9	-1.1	-0.9	-0.9	-0.9	-0.9	-0.2	-0.0	-0.7	-1.0	-0.1
Medication: Co-codamol	0.8	1.0	3.2	0.4	0.9	0.9	1.0	1.1	1.0	-0.3	1.8	0.0	0.4	1.6	0.9
Trunk fat percentage	0.8	3.1	18.6	-1.3	-0.4	-0.8	-0.2	0.0	-0.8	-0.5	0.8	-4.3	-3.5	-1.4	0.2
Taking other prescription medications	0.8	1.3	5.1	0.2	0.1	0.1	-0.3	-0.1	0.4	2.3	0.1	1.5	1.5	1.9	-1.3
Number of incorrect matches in round	0.8	1.4	7.2	-0.4	-1.2	-0.6	-0.3	-0.3	-0.5	0.9	-0.0	-1.5	-1.5	-2.7	-1.3
Number of full sisters	0.8	1.0	4.2	1.1	0.2	0.6	0.3	0.3	0.7	-0.4	0.2	1.4	2.1	1.6	-0.2
Breast cancer (self-reported)	0.8	0.9	3.8	0.6	-1.2	-0.4	0.3	0.4	0.3	1.4	1.3	1.9	0.9	0.6	-0.1
Medication: Aspirin	0.8	1.0	4.7	0.7	0.7	0.9	0.4	0.4	0.8	-0.3	-0.1	1.0	2.2	1.8	-0.9
Number of self-reported non-cancer illnesses	0.8	1.3	5.0	0.1	0.0	0.3	-0.6	-0.7	0.1	1.7	-0.7	1.3	1.8	1.2	-2.2
Diastolic blood pressure, automated reading	0.8	2.5	12.8	2.0	-0.3	1.0	1.1	1.1	1.2	0.6	1.1	3.6	1.8	0.8	1.6
Schizophrenia vs Biploar Disorder	0.7	0.9	1.8	1.3	-0.2	0.7	0.7	0.9	0.8	-1.3	1.0	0.7	1.3	1.3	0.4
Number of treatments/medications taken	0.7	1.2	5.0	0.2	-0.0	0.2	-0.7	-0.6	-0.1	2.2	-1.4	0.8	1.4	0.6	-1.9
Average weekly spirits intake	0.7	0.8	2.6	1.6	-0.1	0.9	1.2	1.4	0.9	0.0	0.8	-0.2	-0.1	-0.2	1.2
Diabetes (mother)	0.7	1.0	3.4	0.7	1.1	0.9	0.7	0.5	0.7	1.6	-0.6	1.0	1.8	0.8	0.3
Townsend deprivation index at recruitment	0.7	1.0	2.5	0.7	1.1	1.0	1.1	1.6	1.2	0.3	1.1	0.1	0.9	0.7	1.3
Stomach or abdominal pain in last month	0.7	0.9	3.7	-0.2	-0.6	-0.5	-0.3	0.0	-0.3	0.7	1.2	-1.8	-1.9	-1.1	-0.1
Trunk fat mass	0.7	3.2	16.0	-1.8	-0.5	-1.0	-0.5	-0.1	-1.0	-0.7	0.8	-4.0	-3.6	-1.4	-0.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	2.2	1.5	0.1	0.6	1.0	1.1	1.0	0.4	1.2	0.6	0.7	0.4	1.2
Lung cancer (father)	0.7	0.8	2.2	-0.9	-1.5	-1.2	-0.9	-0.8	-1.1	0.1	0.2	-0.2	-1.4	-0.8	-0.3
Pulse wave Arterial Stiffness index	0.7	0.8	1.6	-0.9	-1.3	-1.0	0.0	0.2	-0.5	-1.1	1.3	0.1	-0.1	-1.1	1.2
Exposure to tobacco smoke at home	0.7	0.8	2.7	0.7	0.8	1.1	0.5	0.3	0.8	-0.1	-1.1	-0.1	1.6	1.6	-0.4
Headache pain in last month	0.7	1.3	4.1	1.7	0.5	1.1	0.8	0.7	1.3	0.5	0.7	1.6	2.0	1.1	0.0
Worry too long after embarrassment	0.7	1.2	2.4	1.5	0.4	1.0	1.2	1.3	1.3	1.4	1.3	-1.5	-0.1	0.3	0.6
Number of children fathered	0.7	0.8	2.0	-1.2	-0.5	-0.9	-0.8	-0.6	-0.8	0.5	-1.0	-1.0	-0.8	-0.7	-1.4
Suffer from ‘nerves’	0.7	1.1	3.3	1.1	0.2	1.1	0.8	1.1	1.2	-1.8	-0.5	1.1	1.6	0.8	0.4
Overall health rating	0.7	1.6	9.8	1.2	0.1	0.7	0.2	0.0	0.9	3.1	0.5	1.6	0.2	1.4	-1.1
Commuting to job workplace: Car/motor vehicle	0.7	0.7	4.2	-0.7	-0.8	-1.2	-0.7	-0.6	-0.8	-0.5	-0.1	-0.3	-2.0	-0.6	-0.1
Medication: Aspirin	0.7	0.9	4.0	0.6	0.6	0.9	0.4	0.6	0.8	-1.0	-0.0	0.7	2.0	1.5	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	4.5	-0.8	0.4	-0.7	-0.9	-0.5	-0.9	-0.1	-0.2	-2.1	-0.9	-0.7	0.4
Smoking status: Previous	0.7	1.1	4.1	0.7	2.0	1.6	0.8	0.5	0.9	1.0	-0.8	0.5	0.8	1.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	5.0	-2.0	0.6	-0.7	-0.3	0.1	-0.7	-1.3	0.6	-1.7	-2.2	0.1	0.9
Diabetes diagnosed by doctor	0.7	1.1	2.8	-1.6	-0.6	-1.3	-1.6	-1.4	-1.7	-0.7	-0.5	-0.1	-0.7	0.1	-0.6
Friendships satisfaction	0.7	0.8	3.4	1.0	0.2	0.7	0.5	0.6	0.9	-1.2	0.0	1.8	1.1	0.8	-0.8
Irritability	0.7	1.3	5.2	-1.3	-0.6	-1.3	-1.1	-0.6	-1.2	-0.5	-0.1	-2.3	-1.2	-1.2	-0.1
Basal cell carcinoma (self-reported)	0.7	0.9	3.9	-0.7	0.6	-0.0	-1.1	-1.0	-0.8	-0.8	-2.0	-0.2	1.0	0.8	-1.0
Neuroticism (Nagel 2018)	0.6	1.5	3.5	1.5	0.6	1.3	1.6	1.9	1.7	1.2	1.4	-0.3	0.3	0.5	0.9
Worry (Nagel 2018)	0.6	1.2	3.2	1.8	0.1	1.4	1.3	1.6	1.7	0.0	0.0	0.6	1.1	0.9	0.3
Blood White Count	0.6	4.5	12.2	2.3	1.2	1.9	2.1	1.8	1.9	-0.1	0.6	3.0	3.5	2.6	1.9
Ever used hormone-replacement therapy (HRT)	0.6	0.8	3.7	0.6	-1.2	-0.3	-0.7	-0.8	-0.2	-0.3	-1.3	0.4	0.9	0.2	-1.9
Age when periods started (menarche)	0.6	1.4	9.5	-0.8	0.1	-0.5	-0.6	-0.5	-0.9	0.0	-0.0	-3.1	-1.9	-1.3	0.3
Forced vital capacity (FVC)	0.6	2.5	7.7	-0.7	2.8	1.1	1.6	1.9	1.2	-0.8	1.9	-1.3	-0.1	1.2	2.4
Father’s age at death	0.6	0.8	1.8	1.3	0.5	1.2	0.9	0.7	1.2	-0.5	-0.4	0.9	0.9	1.2	-0.3
Worrier / anxious feelings	0.6	1.2	2.9	1.7	0.3	1.1	1.4	1.4	1.4	-0.2	0.9	0.6	1.0	0.8	1.0
Illnesses of mother	0.6	0.7	2.3	0.7	1.5	0.7	0.4	0.6	0.3	-0.0	0.5	-1.1	0.9	0.7	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.7	1.6	0.2	1.0	1.2	1.1	1.4	-0.3	0.6	1.2	1.1	0.4	0.3
Ever highly irritable/argumentative for 2 days	0.6	0.7	3.0	0.2	0.8	0.4	0.8	0.6	0.4	0.4	1.5	0.4	-0.1	-0.7	1.7
Body fat percentage	0.6	2.2	11.7	-0.9	-0.7	-0.7	-0.2	-0.0	-0.7	0.0	0.7	-3.4	-3.1	-1.6	-0.2
Exposure to tobacco smoke outside home	0.6	0.8	2.3	-0.5	-1.4	-0.9	-0.9	-0.5	-0.5	-0.3	-1.4	-0.5	0.3	-0.2	-1.5
Wheeze or whistling in the chest in last year	0.6	1.1	4.1	1.6	0.7	1.2	0.8	1.0	1.3	0.7	0.1	0.5	2.0	0.5	0.4
Shortness of breath walking on level ground	0.6	0.7	1.8	1.1	0.4	0.8	0.4	0.6	0.6	0.1	0.3	0.3	1.3	1.4	1.3
Neck or shoulder pain in last month	0.6	0.9	2.4	0.1	-1.5	-0.9	-1.2	-1.4	-0.6	1.0	-0.2	1.0	-0.3	0.3	-1.2
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	1.9	0.9	0.5	0.9	0.8	0.9	0.7	-0.8	1.4	0.7	1.1	0.3	1.0
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.7	-1.1	-0.8	-1.1	-0.7	-0.9	-1.2	0.4	0.1	-1.3	-1.6	-1.0	-0.0
Medication for cholesterol	0.6	0.8	5.4	-0.7	0.9	-0.3	-0.2	0.0	-0.4	-0.5	0.1	-2.3	-1.4	-0.0	0.9
Asthma (self-reported)	0.6	1.1	5.8	0.5	0.8	0.6	-0.1	-0.1	0.2	1.5	-0.7	1.6	2.4	0.6	-0.5
Medication: Lisinopril	0.6	0.8	3.0	1.1	1.0	1.4	0.7	0.5	0.9	0.4	-0.0	0.4	1.7	0.4	-0.7
Alcohol drinker status: Never	0.6	0.7	1.9	0.0	-1.1	-0.4	-0.5	-0.5	-0.2	0.4	-0.9	-1.4	-1.1	-0.9	-1.3
Pain experienced in last month	0.6	1.0	6.1	-0.0	0.9	0.4	1.1	1.2	0.1	-1.1	0.1	-0.7	0.6	-0.7	2.5
Verbal and Numeric Reasoning (VNR)	0.5	1.3	4.8	0.3	0.7	0.8	0.7	0.9	0.8	-1.2	-0.9	1.7	2.2	1.5	0.3
Bipolar Disorder (2011)	0.5	0.5	4.1	0.1	0.7	0.3	-0.0	-0.5	0.1	2.0	-0.1	0.3	0.6	0.3	-0.0
Pack years adult smoking proportion	0.5	0.7	2.1	-1.2	-0.2	-0.9	-0.8	-0.6	-1.0	-1.0	-0.8	-1.4	-0.6	-0.6	0.3
Relative age voice broke	0.5	0.8	3.0	0.5	1.5	1.0	0.1	0.1	0.5	-0.4	-0.7	0.7	1.2	1.7	-0.3
Chronic bronchitis/emphysema (father)	0.5	0.6	3.1	0.5	-1.0	-0.2	0.2	0.3	0.4	0.0	-0.1	-1.3	0.5	-1.8	-0.9
Allergy	0.5	1.1	4.0	-0.3	-0.7	-0.5	0.3	0.5	-0.2	-2.0	1.2	-0.7	-1.9	-0.9	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.6	-0.4	1.0	0.6	0.4	0.2	0.4	1.2	-0.5	1.3	0.6	1.3	0.3
Asthma	0.5	1.1	5.5	0.3	0.7	0.4	-0.3	-0.2	0.0	1.5	-0.7	1.8	2.3	0.6	-0.5
Pulse wave reflection index	0.5	0.7	3.0	-0.2	-1.2	-0.5	0.1	0.2	-0.2	-0.6	1.4	-0.4	-0.0	-1.7	0.8
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	5.2	0.6	0.0	0.3	0.3	0.3	0.5	-0.0	0.4	2.3	-0.0	1.5	-0.4
Pulse wave peak to peak time	0.5	0.6	1.7	0.4	1.3	0.7	-0.2	-0.3	0.3	0.8	-1.1	-0.7	-0.4	1.0	-1.1
Heart disease (mother)	0.5	0.6	2.2	-1.0	-1.0	-0.3	-0.5	-0.7	-0.3	-1.5	-1.2	-0.2	0.1	-0.1	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.8	-0.9	-1.3	-1.1	-0.8	-0.7	-0.7	0.6	-0.1	0.8	-0.3	-0.2	-0.7
Whole body fat mass	0.5	1.9	9.7	-1.3	-0.4	-0.7	-0.3	-0.0	-0.6	-0.3	0.5	-3.1	-3.0	-1.1	-0.5
Had major operations	0.5	0.6	2.7	-0.3	1.3	-0.0	-0.7	-0.6	-0.3	0.4	-0.5	-0.3	-0.1	1.3	-1.6
Illnesses of siblings: Diabetes	0.5	0.6	1.3	0.8	-0.3	0.9	0.9	1.0	0.9	0.1	-0.3	1.1	1.1	0.6	0.6
Commuting to job workplace: Walk	0.5	0.5	1.9	0.3	0.5	0.5	-0.1	-0.0	0.2	-0.1	-1.0	1.1	1.4	0.7	-1.0
Back pain experienced in last month	0.5	0.8	4.3	0.3	-0.4	-0.1	-0.2	-0.1	0.2	2.1	0.4	-0.4	-1.7	-0.2	-1.1
Osteoarthritis (self-reported)	0.5	0.6	3.8	0.1	-0.7	-0.6	-0.6	-0.8	-0.1	1.3	-0.0	0.3	-0.2	-0.1	-1.9
Average weekly champagne plus white wine intake	0.5	0.7	2.6	0.2	-0.5	0.2	0.6	0.4	0.2	0.0	1.0	-1.3	-1.6	-1.3	0.5
Wears glasses or contact lenses	0.5	0.6	1.9	-0.1	0.8	0.4	0.8	1.1	0.4	0.2	1.4	-0.8	-0.5	0.2	1.3
Illnesses of father: High blood pressure	0.5	0.7	2.7	0.3	0.4	0.7	0.8	1.0	0.9	1.6	0.5	1.0	-0.1	0.8	0.7
Schizophrenia (2018)	0.4	0.7	1.5	1.2	0.4	0.8	0.6	0.7	1.0	-0.9	1.0	-0.1	1.2	1.1	0.2
Alzheimer’s Disease (including proxy)	0.4	0.6	1.6	0.3	1.3	0.8	0.7	0.8	0.6	-0.3	0.2	-0.3	0.2	0.9	1.3
HDL Cholesterol	0.4	0.6	2.1	0.7	-0.6	-0.5	-0.5	-0.6	-0.2	1.2	0.5	1.1	0.0	0.4	-1.4
Lupus	0.4	0.7	2.8	-1.0	0.6	-0.5	-0.3	-0.1	-0.7	-1.3	-0.5	-0.8	-1.7	-0.5	0.5
Schizophrenia (2014)	0.4	0.8	1.9	0.6	0.8	0.8	0.5	0.7	0.8	-1.4	1.1	0.0	1.2	1.1	0.5
Hypothyroidism (self reported)	0.4	0.9	2.4	0.6	1.5	0.8	0.7	1.1	0.8	1.1	0.9	-0.3	0.6	1.4	0.8
Neuroticism	0.4	0.9	2.8	1.0	0.2	1.2	1.2	1.7	1.4	0.9	0.6	-0.7	-0.2	0.0	0.4
Hand grip strength (left)	0.4	1.1	5.0	-0.6	0.3	-0.4	0.7	1.0	-0.0	-0.5	2.0	-0.5	-1.0	-0.9	2.2
Hearing difficulty/problems: Yes	0.4	0.7	2.7	0.4	-0.0	0.1	-0.3	-0.2	0.3	1.6	-0.2	1.1	1.3	0.7	-1.2
Fed-up feelings	0.4	0.8	3.2	0.7	0.7	0.6	1.0	1.2	0.9	0.0	1.8	-0.2	0.1	0.4	1.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.4	0.4	0.6	0.7	0.3	0.4	0.6	0.6	0.0	-0.5	-1.0	0.9	-1.2
Multivitamins +/- minerals	0.4	0.5	2.4	-0.0	0.1	0.0	-0.3	-0.8	-0.7	-0.7	-0.6	-1.6	0.5	-0.6	0.7
Had other major operations	0.4	0.5	2.8	-0.7	0.6	-0.3	-0.6	-0.6	-0.4	-0.0	-0.1	-0.9	-0.7	0.3	-1.7
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.9	1.4	0.2	1.0	1.0	1.1	1.1	1.0	0.5	0.4	0.4	-0.0	0.8
Pulse rate	0.4	0.6	1.8	-0.3	-0.6	-0.7	-0.8	-0.9	-0.7	-0.1	-0.8	1.3	-0.1	0.5	-1.4
Noisy workplace	0.4	0.5	2.2	-0.2	-0.5	-0.5	0.0	0.1	-0.5	0.4	0.6	-1.5	-0.5	-0.6	1.3
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.8	0.5	0.6	0.6	-0.2	-0.1	0.3	0.2	-0.8	1.4	1.5	1.9	-1.0
Breastfed as a baby	0.4	0.5	1.4	0.6	-0.7	-0.2	-0.6	-0.6	-0.1	-0.6	-0.9	1.1	0.7	-0.2	-1.2
Hair/balding pattern: Pattern 4	0.4	1.0	5.3	0.3	-0.7	-0.4	-0.8	-0.9	-0.5	0.2	-1.3	2.3	1.1	1.0	-0.7
Birth weight	0.4	0.8	4.7	-0.4	-0.7	-0.6	0.2	0.2	-0.2	1.0	1.1	-1.0	-2.2	-0.1	0.8
Age at first live birth	0.4	0.7	3.9	-0.2	1.5	0.4	-0.5	-0.2	-0.2	-0.8	0.0	-0.4	1.0	2.0	0.1
Medication: Seretide 50 evohaler	0.4	0.4	1.9	-0.8	0.0	-0.3	-0.9	-0.6	-0.7	0.3	-0.2	-1.4	-0.2	0.5	-0.9
Age at last live birth	0.4	0.6	2.0	0.4	1.2	0.4	0.2	0.4	0.3	0.4	1.4	-0.3	0.1	1.4	0.9
Family relationship satisfaction	0.4	0.5	3.9	-0.3	0.1	0.3	-0.3	-0.3	-0.1	-1.0	-2.0	-0.3	0.7	0.0	-0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.3	-0.7	-0.2	-0.6	-0.2	-0.4	-0.4	0.4	1.5	-1.1	-0.3	-0.8	0.2
Mood swings	0.4	0.6	1.7	0.6	0.2	0.6	0.9	1.3	1.0	-0.3	1.3	0.3	0.5	0.5	1.1
Smoking status: Current	0.4	0.7	2.7	-0.7	-1.6	-1.1	-0.7	-0.7	-0.7	1.1	0.1	-0.4	-0.3	-1.1	-0.2
Mother’s age at death	0.4	0.5	2.6	0.3	-0.7	0.0	0.0	-0.3	-0.1	-1.6	-1.0	0.4	0.8	-0.6	-0.7
Financial situation satisfaction	0.4	0.5	1.1	0.2	1.0	0.3	0.0	-0.1	0.1	-0.6	0.5	1.1	0.9	1.0	0.9
Medication: Blood pressure	0.4	0.8	2.1	0.5	0.5	0.8	0.4	0.3	0.6	0.8	-0.7	1.4	1.3	1.1	-1.3
Medication: Bendroflumethiazide	0.4	0.7	2.3	1.0	1.2	1.1	0.5	0.3	0.6	-0.3	-0.4	0.8	1.5	0.6	-0.4
Leg fat percentage (left)	0.4	1.4	5.4	-0.2	-1.5	-0.7	-0.2	-0.2	-0.5	0.5	0.4	-1.9	-2.3	-1.9	-0.8
Pack years of smoking	0.4	0.6	1.9	-1.1	-0.1	-0.8	-0.6	-0.4	-0.8	-1.4	-0.6	-1.2	-0.4	-0.3	0.4
Bipolar Disorder (2018)	0.3	0.5	1.6	-0.3	-0.3	-0.6	-1.0	-1.1	-0.5	0.4	-0.4	0.2	0.7	-0.2	-1.3
Depression (Nagel 2018)	0.3	0.4	2.0	0.4	0.9	0.8	0.4	0.5	0.7	1.4	-0.1	0.6	0.3	0.5	-0.1
Alzheimer’s Disease (in mother)	0.3	0.3	0.9	-0.9	0.0	-0.7	-0.6	-0.4	-0.7	-0.3	-0.2	-0.6	-0.9	0.1	-0.1
Age at First Birth	0.3	0.4	1.6	0.1	0.4	0.2	-0.3	-0.5	-0.1	-0.5	-1.3	-0.2	0.8	0.8	-0.9
Crohns Disease (2012)	0.3	0.5	1.6	0.7	0.9	0.7	0.6	0.6	0.5	0.1	0.6	0.2	0.8	1.3	0.9
Rheumatoid Arthritis	0.3	0.4	1.4	0.5	0.1	0.3	0.5	0.6	0.3	0.8	1.2	-0.5	-0.0	-0.8	0.8
Blood Red Count	0.3	2.7	8.5	1.0	2.0	1.7	2.2	2.2	1.5	-0.4	1.6	-0.1	-0.2	1.3	2.9
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.3	-1.1	-0.5	-1.0	-1.1	-1.1	-1.1	0.2	0.3	0.1	-0.6	-0.3	-0.7
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.7	0.7	-0.2	0.4	0.3	0.3	0.7	1.3	0.2	1.3	0.2	0.7	-0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.8	-0.3	-0.3	-0.4	-0.9	-0.7	-0.4	0.1	-0.4	-0.2	-1.0	0.2	-1.3
Medication: Metformin	0.3	0.4	1.5	-0.6	1.0	0.2	-0.2	-0.1	-0.2	1.2	0.7	0.3	-0.3	1.1	0.2
Hand grip strength (right)	0.3	0.8	3.1	-0.7	0.5	-0.4	0.4	0.7	-0.1	-0.8	1.6	-1.1	-0.6	-0.7	1.8
Current tobacco smoking	0.3	0.4	1.6	-0.5	-1.3	-0.8	-0.3	-0.4	-0.4	1.2	0.1	-0.1	-0.2	-0.9	0.0
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.9	0.7	-0.6	0.1	0.2	0.2	0.3	-0.7	-0.1	-0.8	-0.7	-0.5	-1.0
Qualifications: CSEs or equivalent	0.3	0.4	1.4	0.5	1.2	0.8	0.8	0.7	0.5	0.1	-0.3	0.2	0.2	1.0	0.7
Medication: Atenolol	0.3	0.4	1.1	-0.9	0.0	-0.4	-0.5	-0.6	-1.0	0.4	-0.6	-1.1	0.3	-0.0	0.3
Medication: Levothyroxine sodium	0.3	0.4	3.1	0.6	0.7	0.4	0.2	0.6	0.5	1.8	-0.1	0.1	0.5	0.3	-0.5
High blood pressure (mother)	0.3	0.4	1.0	-0.4	-0.7	-0.7	-0.7	-0.8	-0.5	-0.2	-0.3	0.9	-0.1	-0.3	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.2	0.7	0.2	0.6	0.4	0.3	0.7	1.5	-0.7	0.9	0.4	-0.1	-0.9
Financial difficulties in last 2 years	0.3	0.5	1.4	-0.8	-0.4	-0.6	-0.9	-0.9	-0.6	0.2	-1.2	0.2	-0.1	0.1	-1.0
Neuroticism score	0.3	0.6	1.6	1.1	0.0	0.8	0.9	1.3	1.3	0.5	0.3	0.1	0.8	0.9	0.1
Weight	0.3	1.5	6.6	-1.6	-0.5	-0.8	-0.4	0.0	-0.5	-0.7	0.9	-2.3	-2.6	-0.8	-0.3
Number of live births	0.3	0.5	2.6	0.4	-0.3	-0.0	0.5	0.6	0.4	0.4	1.6	-0.7	-0.3	-1.0	0.6
Tense / ‘highly strung’	0.3	0.4	1.4	0.9	-0.3	0.5	0.6	0.5	0.7	0.9	-0.2	1.2	0.1	0.5	0.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.8	-0.8	0.8	0.1	-0.3	-0.3	-0.1	-0.3	-1.3	-0.9	0.6	0.2	-0.4
Glaucoma (self-reported)	0.3	0.4	2.7	0.2	-0.7	-0.2	-0.4	-0.3	-0.2	-0.3	-0.8	0.6	1.6	-0.2	-0.1
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.4	0.1	-0.2	0.1	0.3	0.1	0.3	1.1	0.6	1.2	0.1	0.3	0.7
Leg fat percentage (right)	0.3	1.2	4.5	-0.2	-1.3	-0.6	-0.1	-0.0	-0.4	0.7	0.4	-1.9	-2.1	-1.6	-0.8
Comparative body size at age 10	0.3	0.8	3.3	1.8	0.7	1.3	0.7	0.3	0.9	0.9	0.0	0.5	1.2	0.4	-0.3
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.2	-0.4	1.1	0.2	-0.3	-0.5	-0.2	0.9	-0.8	-0.4	0.2	0.4	-0.8
Leg fat mass (right)	0.3	1.1	4.9	-0.7	-0.8	-0.5	-0.2	-0.0	-0.4	0.2	0.4	-2.2	-2.1	-1.1	-0.6
Alcohol intake frequency.	0.3	0.6	2.1	-0.4	-1.5	-0.8	-0.4	-0.5	-0.5	-0.4	0.2	-0.3	-1.1	-1.5	-0.2
Loneliness, isolation	0.3	0.4	1.0	0.8	-1.0	0.2	0.8	0.9	0.9	-0.0	0.4	0.7	0.7	-0.2	0.5
Long-standing illness, disability or infirmity	0.3	0.4	1.8	0.7	0.3	0.6	-0.0	0.2	0.3	1.3	0.3	0.6	0.6	1.1	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	3.2	-0.1	-0.0	-0.4	0.1	0.3	0.0	0.1	1.8	0.6	0.0	0.1	0.7
Medication: Gliclazide	0.3	0.3	1.2	-0.6	0.8	-0.1	-0.4	-0.4	-0.5	1.1	-0.3	-0.6	-0.9	-0.1	-0.5
Commuting to job workplace: Public transport	0.3	0.4	1.4	0.6	0.2	0.3	0.2	0.6	0.4	1.2	0.9	-0.3	1.0	0.3	-0.6
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.4	0.2	-1.0	-0.5	-0.3	-0.5	-0.2	0.3	1.1	0.8	-0.2	-0.4	-1.2
Medication: Paracetamol	0.3	0.5	3.4	-0.1	0.2	0.1	-0.3	-0.5	-0.2	1.8	-0.5	-0.6	-0.9	-0.2	-0.8
Average weekly beer plus cider intake	0.3	0.5	1.5	0.6	0.3	0.1	0.6	0.8	0.4	1.1	1.2	-0.3	-0.3	0.1	1.1
Unable to work because of sickness or disability	0.3	0.4	1.6	0.6	-1.0	-0.3	-0.0	-0.1	-0.1	1.2	-0.4	0.6	-0.4	-0.8	-0.1
Alcohol drinker status: Previous	0.3	0.4	1.1	0.6	1.1	0.9	0.5	0.2	0.4	1.0	0.1	-0.2	0.0	-0.5	0.3
Leg fat mass (left)	0.3	1.2	5.3	-0.7	-1.0	-0.7	-0.3	-0.1	-0.5	-0.0	0.4	-2.3	-2.2	-1.3	-0.6
Ovarian Cancer	0.2	0.2	0.7	0.5	-0.8	-0.3	-0.4	-0.3	-0.3	-0.2	-0.6	0.7	0.8	0.0	-0.0
Fasting Glucose	0.2	0.2	1.0	-0.2	0.5	-0.1	0.0	0.4	-0.1	0.7	-0.2	-0.6	0.1	0.4	1.0
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.1	0.1	0.1	0.1	0.7	0.9	0.6	-0.3	1.0	-0.5	-0.1	0.1	0.3
Blood Eosinophil Count	0.2	1.3	3.9	0.2	-1.0	-0.7	-1.4	-1.6	-1.0	0.4	-2.0	0.2	1.4	-0.5	-1.7
Waist Hip Ratio (WHR)	0.2	0.8	3.4	0.1	-1.5	-0.7	-0.7	-0.5	-0.4	0.9	0.2	-0.7	-0.7	-1.8	-0.5
Smoking Status	0.2	0.4	3.6	-0.1	-0.0	0.1	-0.1	-0.4	-0.1	1.9	-0.6	-0.4	0.3	-0.3	-0.2
Chronotype (morning person)	0.2	0.4	1.2	0.3	-0.4	-0.1	0.7	0.7	0.3	-0.2	0.4	1.0	0.8	-0.2	1.1
Systolic blood pressure, automated reading	0.2	0.6	1.7	-1.1	-0.8	-0.7	-0.3	-0.2	-0.8	-1.3	-0.2	-0.1	-0.2	-0.9	1.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.8	0.3	0.1	0.4	0.1	0.3	0.0	0.5	0.1	0.9	0.1	0.6	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.7	0.5	0.3	0.6	0.6	0.7	0.8	0.5	0.4	0.6	0.3	0.2	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.5	0.3	0.2	0.4	0.4	0.4	0.8	-0.6	0.1	1.2	1.1	1.1	-0.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.1	0.0	0.5	0.5	0.1	0.2	0.6	0.1	-0.6	-0.3	0.4	0.0	-1.0
Body mass index (BMI)	0.2	0.7	1.9	1.4	-0.2	0.9	0.8	0.8	1.1	1.4	0.6	0.2	0.1	0.3	-0.5
Past tobacco smoking	0.2	0.4	2.1	-0.2	-0.9	-0.7	-0.2	-0.1	-0.2	-1.4	0.4	-0.2	-0.6	-0.6	0.5
Had menopause	0.2	0.2	0.7	-0.3	-0.3	-0.5	-0.4	-0.4	-0.2	0.9	-0.3	0.0	0.5	-0.2	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	0.6	0.6	0.7	0.9	0.9	1.0	-0.1	0.5	0.5	0.8	0.2	0.8
Qualifications: None of the above	0.2	0.5	1.6	-0.0	0.2	0.2	0.7	1.0	0.5	-0.2	0.9	-1.0	0.6	0.3	1.3
Heart attack	0.2	0.2	0.7	-0.8	0.8	0.4	0.2	0.2	0.0	-0.1	-0.3	0.3	0.6	0.0	0.6
Diabetes (self-reported)	0.2	0.4	0.9	-0.8	-0.6	-0.7	-0.9	-0.8	-0.9	-0.5	0.1	0.3	-0.4	0.4	-0.3
Illnesses of siblings	0.2	0.3	1.3	-0.6	0.8	-0.3	-0.5	-0.4	-0.6	-0.1	-0.0	-1.1	-0.6	0.1	-0.1
Hip circumference	0.2	0.7	1.5	0.1	1.0	1.1	0.9	1.1	1.2	0.1	0.6	-0.4	-0.8	0.8	-0.6
Falls in the last year	0.2	0.3	1.3	-0.1	-1.2	-0.5	-0.3	0.1	-0.1	-0.9	0.6	0.7	-0.3	-0.2	-0.3
Arm fat mass (right)	0.2	0.6	4.0	-0.5	-0.2	-0.1	-0.1	0.2	-0.0	0.4	0.2	-2.0	-1.6	-0.5	-0.7
Birth weight of first child	0.2	0.4	1.4	0.1	-0.9	-0.6	-0.4	-0.3	-0.4	1.1	-0.1	-0.2	-1.2	-0.2	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.3	0.6	1.1	0.6	0.4	0.8	0.6	0.9	0.3	-0.4	0.2	0.6	-0.3
High blood pressure (siblings)	0.2	0.3	1.5	0.2	-0.2	0.1	0.4	0.5	0.3	0.2	0.1	1.2	0.3	0.6	0.9
Number of full brothers	0.2	0.2	0.9	0.4	0.9	0.6	0.4	0.1	0.3	1.0	-0.2	0.3	0.2	-0.3	0.3
Qualifications: College or University degree	0.2	0.7	2.5	-0.1	0.0	0.3	-0.6	-0.8	-0.3	0.5	-1.3	1.6	1.2	0.6	-1.0
Medication: Blood pressure	0.2	0.4	2.9	0.3	0.4	0.4	0.2	-0.1	0.0	1.7	-0.5	0.7	0.9	0.5	0.2
Arm fat percentage (left)	0.2	0.7	4.0	0.3	-0.1	0.4	0.5	0.6	0.3	0.5	0.6	-2.0	-1.6	-0.6	-0.1
Arm fat mass (left)	0.2	0.7	4.3	-0.5	-0.3	-0.1	-0.0	0.2	-0.0	0.1	0.1	-2.1	-1.6	-0.4	-0.7
Eye problems/disorders: Glaucoma	0.2	0.2	1.2	0.4	-0.7	-0.1	0.1	0.0	0.0	-0.6	-0.6	0.3	1.1	-0.6	0.2
Ever smoked	0.2	0.3	2.5	0.3	0.0	0.1	-0.2	-0.3	-0.1	1.6	-0.4	0.4	0.8	0.2	-0.5
Cholesterol lowering medication	0.2	0.3	2.4	0.2	-0.3	0.1	-0.1	-0.3	-0.1	-0.4	-0.1	0.9	1.5	-0.0	-0.0
Bipolar Disorder or Schizophrenia	0.1	0.4	1.8	0.8	0.1	0.3	-0.2	-0.1	0.5	-0.4	0.6	0.0	1.3	0.8	-0.6
Crohns Disease (2017)	0.1	0.3	0.8	0.7	-0.2	0.3	0.5	0.6	0.5	-0.9	0.8	0.0	0.3	0.7	-0.0
Body Mass Index (BMI) (2010)	0.1	0.2	0.5	-0.7	0.2	-0.1	-0.4	-0.4	-0.4	0.5	-0.5	-0.2	-0.4	-0.0	-0.7
Blood Platelet Count	0.1	1.0	3.5	-1.7	-0.4	-0.9	-0.6	-0.6	-0.8	-0.1	0.3	-1.9	-1.3	-0.9	-0.3
Heel T-Score	0.1	1.1	3.2	-1.8	0.1	-0.8	-1.2	-1.0	-1.0	-1.7	-1.8	-0.3	0.1	-0.4	-0.4
Systolic Blood Pressure	0.1	0.5	1.4	-1.0	0.2	-0.4	-0.4	-0.4	-0.7	-0.9	-0.3	0.9	0.9	0.1	1.2
Sensitivity / hurt feelings	0.1	0.2	0.6	0.4	0.2	0.6	0.6	0.6	0.7	-0.0	0.3	-0.3	-0.4	0.1	-0.3
Relative age of first facial hair	0.1	0.2	1.4	-0.1	0.7	0.3	-0.0	0.1	0.0	-1.2	0.2	-0.8	-0.2	0.4	0.2
Severe depression (siblings)	0.1	0.1	0.2	0.0	-0.4	-0.0	0.2	0.1	0.2	0.3	0.5	-0.2	0.4	0.1	0.4
Leg fat-free mass (left)	0.1	0.5	1.6	-1.0	0.6	0.0	0.1	0.6	0.2	-1.2	0.9	-1.0	-0.9	0.6	0.2
Leg predicted mass (left)	0.1	0.5	1.5	-1.0	0.7	0.0	0.1	0.6	0.2	-1.2	0.9	-1.0	-0.9	0.6	0.2
Waist circumference	0.1	0.3	0.9	0.2	-0.3	0.3	0.4	0.6	0.6	0.7	0.8	-0.5	-1.0	-0.4	-0.7
Alcohol usually taken with meals	0.1	0.2	0.9	0.6	-1.0	0.3	0.2	-0.1	0.3	0.4	-0.1	0.6	0.4	-0.5	-0.5
Pain all over the body in last month	0.1	0.1	0.4	-0.2	-0.2	-0.0	-0.3	-0.1	0.1	0.0	-0.6	0.4	0.6	-0.3	-0.3
Arm fat percentage (right)	0.1	0.6	2.4	0.3	0.1	0.4	0.5	0.5	0.4	0.9	0.6	-1.6	-1.4	-0.4	-0.2
Trunk fat-free mass	0.1	0.5	3.0	-1.7	0.2	-0.5	-0.4	0.1	-0.2	-0.9	0.5	-0.1	-0.9	0.4	-0.5
Medication: Lansoprazole	0.1	0.1	0.6	0.0	0.0	-0.0	-0.3	-0.2	-0.3	0.1	-0.3	-0.2	0.8	-0.0	-0.1
Trunk predicted mass	0.1	0.5	3.2	-1.8	0.2	-0.6	-0.5	0.1	-0.3	-1.0	0.4	-0.1	-0.9	0.4	-0.6
Medication: Paracetamol	0.1	0.2	1.0	0.3	0.2	0.2	0.0	-0.0	0.0	1.0	0.1	-1.0	-0.9	-0.3	-0.0
Arm fat-free mass (right)	0.1	0.3	1.2	-1.1	0.1	-0.3	-0.2	0.3	0.0	-1.1	0.5	-0.7	-0.7	0.0	-0.2
Health satisfaction	0.1	0.2	0.9	-0.2	-0.2	-0.3	-0.4	-0.2	-0.1	0.5	-0.3	0.4	-0.8	0.1	-1.0
Mean time to correctly identify matches	0.1	0.2	1.3	-0.0	-0.1	0.3	-0.0	0.0	0.2	0.2	-0.7	-1.1	-0.7	-0.3	-0.6
Arm predicted mass (right)	0.1	0.3	1.1	-1.1	0.2	-0.3	-0.1	0.3	0.0	-0.8	0.5	-0.8	-0.6	0.1	-0.3
Pulse rate, automated reading	0.1	0.3	1.3	0.6	-0.3	0.3	0.6	0.6	0.4	-0.2	0.6	1.2	-0.5	0.2	0.6
Whole body fat-free mass	0.1	0.4	1.8	-1.4	0.4	-0.2	-0.2	0.3	0.0	-1.0	0.6	-0.4	-0.8	0.6	-0.3
Leg fat-free mass (right)	0.1	0.6	1.5	-0.8	0.7	0.2	0.3	0.7	0.4	-1.2	1.2	-0.9	-0.9	0.6	0.5
Whole body water mass	0.1	0.4	1.7	-1.3	0.5	-0.2	-0.1	0.4	0.0	-0.9	0.6	-0.4	-0.7	0.7	-0.2
Leg predicted mass (right)	0.1	0.6	1.5	-0.8	0.7	0.1	0.2	0.7	0.3	-1.2	1.2	-1.0	-1.0	0.5	0.5
Ever taken oral contraceptive pill	0.1	0.1	0.5	0.6	0.3	0.4	0.2	0.1	0.1	0.3	-0.2	0.7	0.4	0.1	-0.4
Basal metabolic rate	0.1	0.5	1.9	-1.4	0.2	-0.4	-0.1	0.4	-0.1	-0.9	0.8	-0.9	-1.3	0.3	-0.2
Arm fat-free mass (left)	0.1	0.4	1.8	-1.3	-0.3	-0.6	-0.5	-0.1	-0.3	-0.8	0.3	-0.4	-0.8	0.2	-0.7
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.9	-1.0	0.3	0.1	-0.0	-0.0	-0.3	-0.3	-0.4	0.0	0.4	-0.3	0.4
Arm predicted mass (left)	0.1	0.4	2.0	-1.4	0.0	-0.5	-0.4	-0.0	-0.3	-0.6	0.5	-0.6	-0.9	0.0	-0.6
Reaction Time	0.0	0.1	0.2	0.3	-0.4	0.3	0.1	0.2	0.5	0.4	-0.3	0.0	-0.3	0.0	0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
BMI	0.0	0.3	1.3	0.9	0.3	0.4	-0.1	-0.1	0.1	1.1	0.2	-0.7	-0.2	-0.3	-0.6
Hair Pigment	0.0	1.4	5.1	-0.8	-0.9	-0.5	-0.3	-0.6	-0.8	-1.0	-0.2	-2.2	-2.2	-1.6	0.6
Tanning	0.0	0.2	0.9	-0.3	0.7	0.5	-0.2	-0.2	0.0	-0.1	-0.9	0.1	-0.3	-0.3	-0.9
Medication for pain relief, constipation, heartburn	0.0	0.1	0.2	-0.2	0.4	0.0	0.2	-0.0	-0.0	-0.4	0.4	-0.4	-0.4	0.1	0.3

Hub : Genes

TSPYL1

Models

Trait associations