[Hub]/) : Traits : Height :

chr12:25,589,747-32,442,681

Best TWAS P=1.06e-118 · Best GWAS P=3.38e-115 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC91 0.08 0.06 lasso 6 0.07 9.4e-09 -22.41 19.6 2.3e-85 -0.92 0.25 0.75 FALSE
2 CommonMind Brain Pre-frontal Cortex DENND5B 0.12 0.10 lasso 1 0.10 1.2e-11 -6.08 -6.1 1.2e-09 0.01 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex MRPS35 0.07 0.00 bslmm 555 0.03 8.0e-05 -0.85 -9.6 1.2e-21 0.37 0.05 0.16 FALSE
4 GTEx Adipose Subcutaneous IPO8 0.13 0.09 lasso 6 0.12 2.7e-10 4.22 -5.7 1.3e-08 0.00 0.25 0.75 FALSE
5 GTEx Adipose Subcutaneous RP11-996F15.2 0.46 0.38 lasso 10 0.38 4.1e-33 11.96 12.1 7.1e-34 0.04 0.00 1.00 FALSE
6 GTEx Adipose Visceral Omentum FAR2 0.17 0.01 lasso 5 0.00 2.2e-01 0.65 5.5 3.7e-08 0.03 0.16 0.15 FALSE
7 GTEx Adipose Visceral Omentum RP11-996F15.2 0.40 0.34 enet 12 0.33 7.9e-18 11.96 11.7 8.5e-32 0.03 0.00 1.00 FALSE
8 GTEx Adrenal Gland CCDC91 0.16 0.01 lasso 16 0.03 3.5e-02 6.11 -12.3 9.3e-35 0.39 0.08 0.53 FALSE
9 GTEx Adrenal Gland RP11-967K21.1 0.22 0.02 lasso 4 0.02 6.5e-02 9.37 7.2 5.2e-13 -0.50 0.11 0.09 TRUE
10 GTEx Adrenal Gland RP11-996F15.2 0.62 0.55 lasso 7 0.55 3.0e-23 11.96 12.3 1.6e-34 0.04 0.00 1.00 FALSE
11 GTEx Artery Aorta CCDC91 0.16 0.00 enet 37 0.02 4.1e-02 -22.25 -16.0 1.6e-57 0.55 0.08 0.78 TRUE
12 GTEx Artery Aorta RP11-967K21.1 0.07 0.02 lasso 7 0.01 7.9e-02 11.68 19.4 1.0e-83 -0.85 0.08 0.78 FALSE
13 GTEx Artery Aorta RP11-996F15.2 0.35 0.28 lasso 4 0.28 1.5e-15 11.96 11.9 1.2e-32 0.04 0.00 1.00 FALSE
14 GTEx Artery Coronary RP11-967K21.1 0.18 0.12 lasso 7 0.07 1.8e-03 9.60 10.0 1.3e-23 -0.58 0.27 0.53 FALSE
15 GTEx Artery Coronary RP11-996F15.2 0.54 0.44 enet 20 0.43 9.0e-16 12.10 10.4 2.3e-25 0.05 0.00 1.00 TRUE
16 GTEx Artery Tibial IPO8 0.17 0.14 lasso 4 0.14 4.5e-11 4.27 -5.3 8.9e-08 0.03 0.65 0.35 FALSE
17 GTEx Artery Tibial DENND5B 0.08 0.00 enet 13 0.01 1.1e-01 -6.17 -5.3 1.2e-07 0.06 0.08 0.50 FALSE
18 GTEx Artery Tibial RP11-967K21.1 0.09 0.10 lasso 11 0.07 2.4e-06 8.74 10.5 1.4e-25 -0.61 0.48 0.52 FALSE
19 GTEx Artery Tibial RP11-996F15.2 0.44 0.40 enet 28 0.44 1.2e-37 12.10 12.2 1.7e-34 0.06 0.00 1.00 FALSE
20 GTEx Brain Cerebellar Hemisphere RP11-996F15.2 0.30 0.11 enet 24 0.17 3.7e-05 11.96 11.8 2.3e-32 0.04 0.01 0.98 TRUE
21 GTEx Brain Cerebellum RP11-996F15.2 0.25 0.15 lasso 4 0.10 7.6e-04 11.96 11.9 8.4e-33 0.04 0.01 0.94 FALSE
22 GTEx Brain Frontal Cortex BA9 RP11-996F15.2 0.27 0.01 enet 28 0.02 8.9e-02 -2.75 5.5 4.3e-08 0.05 0.04 0.60 FALSE
23 GTEx Breast Mammary Tissue SSPN 0.27 0.00 lasso 9 0.02 4.1e-02 3.49 -5.1 2.8e-07 0.07 0.27 0.08 FALSE
24 GTEx Breast Mammary Tissue RP11-283G6.5 0.17 0.02 enet 9 0.02 2.9e-02 3.49 -5.5 4.8e-08 0.05 0.11 0.09 FALSE
25 GTEx Breast Mammary Tissue RP11-996F15.2 0.45 0.35 lasso 8 0.31 1.2e-16 12.10 12.3 1.2e-34 0.05 0.00 1.00 FALSE
26 GTEx Breast Mammary Tissue (Male) RP11-996F15.2 0.52 0.28 lasso 9 0.23 4.1e-06 11.96 12.5 7.4e-36 0.05 0.01 0.98 TRUE
27 GTEx Breast Mammary Tissue (Female) RP11-996F15.2 0.42 0.38 lasso 1 0.35 3.5e-11 11.96 12.0 5.5e-33 0.04 0.00 1.00 FALSE
28 GTEx Cells EBV-transformed lymphocytes IPO8 0.22 0.14 lasso 4 0.14 2.5e-05 -6.42 -6.2 5.3e-10 0.01 0.02 0.97 FALSE
29 GTEx Cells EBV-transformed lymphocytes RP11-996F15.2 0.27 0.24 lasso 4 0.23 6.0e-08 11.96 11.7 1.1e-31 0.04 0.01 0.99 FALSE
30 GTEx Cells Transformed fibroblasts ERGIC2 0.12 0.03 enet 23 0.05 1.4e-04 11.96 -10.3 5.1e-25 -0.02 0.01 0.99 FALSE
31 GTEx Cells Transformed fibroblasts CCDC91 0.10 0.10 lasso 5 0.09 5.5e-07 -20.69 -21.5 2.4e-102 0.84 0.14 0.85 FALSE
32 GTEx Cells Transformed fibroblasts RP11-967K21.1 0.07 0.07 lasso 2 0.07 3.7e-06 -22.58 23.2 1.1e-118 -0.96 0.08 0.92 TRUE
33 GTEx Cells Transformed fibroblasts RP11-996F15.2 0.34 0.33 lasso 7 0.34 7.3e-26 11.96 11.6 2.5e-31 0.04 0.00 1.00 FALSE
34 GTEx Colon Sigmoid RP11-996F15.2 0.42 0.27 lasso 7 0.29 7.7e-11 11.96 11.7 1.9e-31 0.05 0.00 1.00 FALSE
35 GTEx Colon Transverse CCDC91 0.11 0.01 lasso 6 0.00 4.6e-01 -20.96 -19.3 2.7e-83 0.81 0.09 0.76 FALSE
36 GTEx Colon Transverse RP11-967K21.1 0.12 0.07 lasso 8 0.05 1.6e-03 8.87 11.5 1.3e-30 -0.57 0.19 0.72 FALSE
37 GTEx Colon Transverse RP11-996F15.2 0.31 0.32 lasso 1 0.31 3.5e-15 11.96 12.0 5.5e-33 0.04 0.00 1.00 FALSE
38 GTEx Esophagus Gastroesophageal Junction RP11-996F15.2 0.50 0.42 lasso 8 0.42 1.4e-16 11.96 11.8 2.6e-32 0.05 0.00 1.00 FALSE
39 GTEx Esophagus Mucosa MRPS35 0.18 0.00 enet 20 0.01 6.6e-02 0.53 10.1 7.5e-24 -0.37 0.06 0.48 FALSE
40 GTEx Esophagus Mucosa CCDC91 0.18 0.04 enet 36 0.03 3.1e-03 11.69 -15.8 4.7e-56 0.57 0.19 0.56 FALSE
41 GTEx Esophagus Mucosa RP11-996F15.2 0.39 0.43 lasso 7 0.45 6.2e-33 11.96 12.1 1.6e-33 0.05 0.00 1.00 FALSE
42 GTEx Esophagus Muscularis RP11-967K21.1 0.07 0.06 lasso 5 0.04 2.2e-03 8.88 10.2 1.2e-24 -0.58 0.26 0.27 FALSE
43 GTEx Esophagus Muscularis RP11-860B13.1 0.19 0.07 enet 24 0.06 2.1e-04 -0.85 -9.3 9.2e-21 0.40 0.32 0.58 FALSE
44 GTEx Esophagus Muscularis RP11-996F15.2 0.56 0.45 enet 31 0.47 1.3e-31 11.96 11.7 1.5e-31 0.02 0.00 1.00 FALSE
45 GTEx Heart Atrial Appendage CCDC91 0.10 0.06 lasso 8 0.04 4.4e-03 -20.69 -21.0 2.7e-98 0.84 0.06 0.87 FALSE
46 GTEx Heart Atrial Appendage RP11-967K21.1 0.08 0.09 lasso 1 0.08 2.3e-04 -22.58 22.6 7.1e-113 -0.92 0.06 0.88 FALSE
47 GTEx Heart Atrial Appendage RP11-283G6.5 0.27 -0.01 enet 8 0.02 4.5e-02 3.33 -5.1 2.8e-07 0.04 0.07 0.12 FALSE
48 GTEx Heart Left Ventricle IPO8 0.14 0.00 lasso 7 0.03 8.6e-03 -6.42 -5.4 8.3e-08 0.01 0.03 0.88 FALSE
49 GTEx Lung CCDC91 0.14 0.00 enet 33 0.06 1.5e-05 -8.40 -10.5 7.3e-26 0.37 0.27 0.12 FALSE
50 GTEx Lung IPO8 0.07 0.06 lasso 5 0.07 7.5e-06 4.22 -5.4 6.5e-08 0.00 0.10 0.90 FALSE
51 GTEx Lung RP11-996F15.2 0.50 0.46 lasso 5 0.46 1.9e-39 11.96 11.9 8.0e-33 0.04 0.00 1.00 FALSE
52 GTEx Muscle Skeletal RP11-967K21.1 0.04 0.01 lasso 9 0.00 2.9e-01 -20.96 20.5 4.3e-93 -0.88 0.12 0.61 FALSE
53 GTEx Muscle Skeletal RP11-996F15.2 0.24 0.26 lasso 11 0.25 9.3e-25 12.10 12.3 1.1e-34 0.05 0.00 1.00 FALSE
54 GTEx Nerve Tibial IPO8 0.21 0.16 lasso 6 0.15 1.3e-10 -6.47 -6.5 9.0e-11 -0.02 0.02 0.98 TRUE
55 GTEx Nerve Tibial RP11-996F15.2 0.52 0.53 lasso 5 0.56 3.3e-47 11.96 11.6 3.4e-31 0.05 0.00 1.00 FALSE
56 GTEx Ovary RP11-996F15.2 0.50 0.46 enet 22 0.54 1.1e-15 10.90 10.9 1.5e-27 0.06 0.01 0.99 FALSE
57 GTEx Pancreas RP11-996F15.2 0.56 0.46 enet 22 0.48 1.8e-22 11.96 12.2 1.9e-34 0.03 0.00 1.00 FALSE
58 GTEx Pituitary RP11-967K21.1 0.20 0.04 lasso 7 0.04 4.4e-02 10.37 15.7 1.5e-55 -0.64 0.06 0.54 FALSE
59 GTEx Pituitary RP11-996F15.2 0.54 0.42 lasso 8 0.32 7.7e-09 11.96 12.1 1.8e-33 0.05 0.00 1.00 FALSE
60 GTEx Prostate RP11-996F15.2 0.49 0.36 enet 32 0.39 6.0e-11 11.96 11.9 1.0e-32 0.04 0.00 1.00 FALSE
61 GTEx Skin Not Sun Exposed Suprapubic CCDC91 0.26 0.05 lasso 15 0.04 4.1e-03 -22.00 -22.0 2.7e-107 0.85 0.18 0.81 TRUE
62 GTEx Skin Not Sun Exposed Suprapubic TMTC1 0.21 0.00 enet 32 0.01 1.2e-01 0.43 5.1 2.6e-07 -0.01 0.09 0.33 FALSE
63 GTEx Skin Not Sun Exposed Suprapubic RP11-996F15.2 0.44 0.28 enet 55 0.28 1.1e-15 11.96 11.4 4.5e-30 0.02 0.00 1.00 FALSE
64 GTEx Skin Sun Exposed Lower leg CCDC91 0.09 0.01 enet 8 0.01 2.6e-02 -22.58 -22.1 6.4e-108 0.87 0.10 0.83 FALSE
65 GTEx Skin Sun Exposed Lower leg IPO8 0.23 0.08 lasso 10 0.13 1.1e-10 -6.50 -6.3 3.3e-10 0.00 0.03 0.97 FALSE
66 GTEx Skin Sun Exposed Lower leg RP11-996F15.2 0.50 0.48 enet 21 0.50 1.5e-47 12.10 12.1 1.9e-33 0.04 0.00 1.00 FALSE
67 GTEx Small Intestine Terminal Ileum RP11-996F15.2 0.60 0.51 lasso 5 0.46 7.1e-12 12.10 12.5 1.2e-35 0.04 0.00 1.00 FALSE
68 GTEx Spleen RP11-996F15.2 0.53 0.49 lasso 5 0.46 1.7e-13 12.10 11.9 8.4e-33 0.06 0.00 1.00 FALSE
69 GTEx Stomach RP11-996F15.2 0.35 0.41 lasso 3 0.40 1.4e-20 11.96 11.9 1.8e-32 0.03 0.00 1.00 FALSE
70 GTEx Testis RP11-996F15.2 0.28 0.35 lasso 2 0.37 2.7e-17 11.96 11.6 3.5e-31 0.03 0.00 1.00 FALSE
71 GTEx Thyroid CCDC91 0.15 0.12 enet 42 0.12 2.9e-09 -22.25 -16.7 1.2e-62 0.83 0.11 0.89 TRUE
72 GTEx Thyroid RP11-967K21.1 0.05 0.00 enet 7 0.00 2.8e-01 8.21 6.2 4.2e-10 -0.42 0.09 0.37 FALSE
73 GTEx Thyroid RP11-996F15.2 0.54 0.54 lasso 8 0.55 9.1e-50 12.10 12.1 6.1e-34 0.04 0.00 1.00 FALSE
74 GTEx Uterus RP11-996F15.2 0.37 0.08 enet 16 0.22 3.3e-05 11.96 9.1 7.7e-20 0.02 0.01 0.96 FALSE
75 GTEx Vagina RP11-996F15.2 0.44 0.31 enet 23 0.27 5.9e-07 12.10 11.0 4.6e-28 0.05 0.01 0.99 FALSE
76 GTEx Whole Blood RP11-996F15.2 0.20 0.18 enet 11 0.18 9.2e-17 11.96 12.2 5.4e-34 0.07 0.00 1.00 FALSE
77 METSIM Adipose FAR2 0.05 0.02 enet 10 0.03 6.2e-05 6.88 8.2 2.3e-16 0.08 0.96 0.03 FALSE
78 NTR Blood CCDC91 0.01 0.01 blup 648 0.00 9.0e-03 8.68 -16.6 1.1e-61 0.77 0.24 0.45 FALSE
79 ROSMAP Brain Pre-frontal Cortex FGFR1OP2 0.04 0.00 bslmm 525 0.00 7.9e-02 1.96 6.1 8.7e-10 -0.07 0.00 0.01 TRUE
80 ROSMAP Brain Pre-frontal Cortex DENND5B 0.19 0.09 lasso 6 0.15 2.4e-19 -6.08 -7.7 1.3e-14 0.01 0.36 0.64 TRUE
81 ROSMAP Brain Pre-frontal Cortex RP11-996F15.2 0.21 0.22 lasso 7 0.24 5.1e-30 11.96 11.7 8.1e-32 0.05 0.00 1.00 FALSE
82 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC91 0.04 0.04 lasso 3 0.03 1.8e-06 -22.43 -22.4 2.4e-111 0.98 0.19 0.81 FALSE
83 The Cancer Genome Atlas Breast Invasive Carcinoma DENND5B 0.01 0.01 blup 101 0.01 1.2e-03 -4.82 -6.6 4.4e-11 0.02 0.05 0.15 FALSE
84 The Cancer Genome Atlas Breast Invasive Carcinoma ERGIC2 0.03 0.00 blup 62 0.02 2.6e-04 -3.82 -7.5 7.1e-14 0.00 0.03 0.52 FALSE
85 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC91 0.06 0.02 blup 174 0.04 2.9e-05 9.52 -18.8 6.8e-79 0.82 0.54 0.43 TRUE
86 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ERGIC2 0.04 0.03 lasso 2 0.03 1.3e-04 11.96 -11.8 2.3e-32 -0.03 0.01 0.99 FALSE
87 The Cancer Genome Atlas Brain Lower Grade Glioma ERGIC2 0.06 0.02 enet 9 0.04 4.8e-05 6.88 -9.5 1.7e-21 -0.08 0.01 0.90 FALSE
88 The Cancer Genome Atlas Liver Hepatocellular Carcinoma C12orf72 0.11 0.00 blup 57 0.02 5.4e-02 2.64 7.0 2.2e-12 -0.10 0.01 0.24 FALSE
89 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SSPN 0.15 0.04 lasso 3 0.07 4.6e-04 5.66 -6.3 2.9e-10 -0.02 0.02 0.54 TRUE
90 The Cancer Genome Atlas Lung Adenocarcinoma CCDC91 0.09 0.01 blup 170 0.02 1.0e-03 -22.25 -19.1 2.9e-81 0.80 0.09 0.83 FALSE
91 The Cancer Genome Atlas Lung Adenocarcinoma IPO8 0.06 0.04 blup 58 0.04 1.5e-05 4.34 -5.8 8.8e-09 0.01 0.35 0.64 FALSE
92 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IPO8 0.04 0.03 blup 58 0.03 9.7e-05 4.22 -5.4 5.9e-08 0.00 0.30 0.54 FALSE
93 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC91 0.09 0.11 lasso 2 0.12 2.3e-05 -22.79 -22.8 5.5e-115 1.00 0.05 0.93 FALSE
94 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC91 0.22 0.00 enet 16 0.04 2.5e-05 11.59 -12.7 4.8e-37 0.44 0.02 0.08 FALSE
95 The Cancer Genome Atlas Prostate Adenocarcinoma ERGIC2 0.05 0.02 lasso 4 0.05 3.3e-06 8.68 -6.8 8.5e-12 0.01 0.05 0.78 FALSE
96 The Cancer Genome Atlas Thyroid Carcinoma CCDC91 0.40 0.12 blup 175 0.14 4.9e-13 -22.06 -17.5 2.3e-68 0.65 1.00 0.00 FALSE
97 The Cancer Genome Atlas Thyroid Carcinoma DENND5B 0.08 0.04 enet 12 0.06 2.4e-06 7.00 -5.9 3.2e-09 0.05 0.02 0.98 FALSE
98 The Cancer Genome Atlas Thyroid Carcinoma ERGIC2 0.19 0.10 blup 62 0.11 1.1e-10 10.90 -11.4 5.9e-30 -0.04 0.01 0.99 FALSE