[Hub]/) : Traits : Height : ← →

chr12:25,589,747-32,442,681

Best TWAS P=1.06e-118 · Best GWAS P=3.38e-115 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CCDC91	0.08	0.06	lasso	6	0.07	9.4e-09	-22.41	19.6	2.3e-85	-0.92	0.25	0.75	FALSE
2	CommonMind	Brain Pre-frontal Cortex	DENND5B	0.12	0.10	lasso	1	0.10	1.2e-11	-6.08	-6.1	1.2e-09	0.01	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	MRPS35	0.07	0.00	bslmm	555	0.03	8.0e-05	-0.85	-9.6	1.2e-21	0.37	0.05	0.16	FALSE
4	GTEx	Adipose Subcutaneous	IPO8	0.13	0.09	lasso	6	0.12	2.7e-10	4.22	-5.7	1.3e-08	0.00	0.25	0.75	FALSE
5	GTEx	Adipose Subcutaneous	RP11-996F15.2	0.46	0.38	lasso	10	0.38	4.1e-33	11.96	12.1	7.1e-34	0.04	0.00	1.00	FALSE
6	GTEx	Adipose Visceral Omentum	FAR2	0.17	0.01	lasso	5	0.00	2.2e-01	0.65	5.5	3.7e-08	0.03	0.16	0.15	FALSE
7	GTEx	Adipose Visceral Omentum	RP11-996F15.2	0.40	0.34	enet	12	0.33	7.9e-18	11.96	11.7	8.5e-32	0.03	0.00	1.00	FALSE
8	GTEx	Adrenal Gland	CCDC91	0.16	0.01	lasso	16	0.03	3.5e-02	6.11	-12.3	9.3e-35	0.39	0.08	0.53	FALSE
9	GTEx	Adrenal Gland	RP11-967K21.1	0.22	0.02	lasso	4	0.02	6.5e-02	9.37	7.2	5.2e-13	-0.50	0.11	0.09	TRUE
10	GTEx	Adrenal Gland	RP11-996F15.2	0.62	0.55	lasso	7	0.55	3.0e-23	11.96	12.3	1.6e-34	0.04	0.00	1.00	FALSE
11	GTEx	Artery Aorta	CCDC91	0.16	0.00	enet	37	0.02	4.1e-02	-22.25	-16.0	1.6e-57	0.55	0.08	0.78	TRUE
12	GTEx	Artery Aorta	RP11-967K21.1	0.07	0.02	lasso	7	0.01	7.9e-02	11.68	19.4	1.0e-83	-0.85	0.08	0.78	FALSE
13	GTEx	Artery Aorta	RP11-996F15.2	0.35	0.28	lasso	4	0.28	1.5e-15	11.96	11.9	1.2e-32	0.04	0.00	1.00	FALSE
14	GTEx	Artery Coronary	RP11-967K21.1	0.18	0.12	lasso	7	0.07	1.8e-03	9.60	10.0	1.3e-23	-0.58	0.27	0.53	FALSE
15	GTEx	Artery Coronary	RP11-996F15.2	0.54	0.44	enet	20	0.43	9.0e-16	12.10	10.4	2.3e-25	0.05	0.00	1.00	TRUE
16	GTEx	Artery Tibial	IPO8	0.17	0.14	lasso	4	0.14	4.5e-11	4.27	-5.3	8.9e-08	0.03	0.65	0.35	FALSE
17	GTEx	Artery Tibial	DENND5B	0.08	0.00	enet	13	0.01	1.1e-01	-6.17	-5.3	1.2e-07	0.06	0.08	0.50	FALSE
18	GTEx	Artery Tibial	RP11-967K21.1	0.09	0.10	lasso	11	0.07	2.4e-06	8.74	10.5	1.4e-25	-0.61	0.48	0.52	FALSE
19	GTEx	Artery Tibial	RP11-996F15.2	0.44	0.40	enet	28	0.44	1.2e-37	12.10	12.2	1.7e-34	0.06	0.00	1.00	FALSE
20	GTEx	Brain Cerebellar Hemisphere	RP11-996F15.2	0.30	0.11	enet	24	0.17	3.7e-05	11.96	11.8	2.3e-32	0.04	0.01	0.98	TRUE
21	GTEx	Brain Cerebellum	RP11-996F15.2	0.25	0.15	lasso	4	0.10	7.6e-04	11.96	11.9	8.4e-33	0.04	0.01	0.94	FALSE
22	GTEx	Brain Frontal Cortex BA9	RP11-996F15.2	0.27	0.01	enet	28	0.02	8.9e-02	-2.75	5.5	4.3e-08	0.05	0.04	0.60	FALSE
23	GTEx	Breast Mammary Tissue	SSPN	0.27	0.00	lasso	9	0.02	4.1e-02	3.49	-5.1	2.8e-07	0.07	0.27	0.08	FALSE
24	GTEx	Breast Mammary Tissue	RP11-283G6.5	0.17	0.02	enet	9	0.02	2.9e-02	3.49	-5.5	4.8e-08	0.05	0.11	0.09	FALSE
25	GTEx	Breast Mammary Tissue	RP11-996F15.2	0.45	0.35	lasso	8	0.31	1.2e-16	12.10	12.3	1.2e-34	0.05	0.00	1.00	FALSE
26	GTEx	Breast Mammary Tissue (Male)	RP11-996F15.2	0.52	0.28	lasso	9	0.23	4.1e-06	11.96	12.5	7.4e-36	0.05	0.01	0.98	TRUE
27	GTEx	Breast Mammary Tissue (Female)	RP11-996F15.2	0.42	0.38	lasso	1	0.35	3.5e-11	11.96	12.0	5.5e-33	0.04	0.00	1.00	FALSE
28	GTEx	Cells EBV-transformed lymphocytes	IPO8	0.22	0.14	lasso	4	0.14	2.5e-05	-6.42	-6.2	5.3e-10	0.01	0.02	0.97	FALSE
29	GTEx	Cells EBV-transformed lymphocytes	RP11-996F15.2	0.27	0.24	lasso	4	0.23	6.0e-08	11.96	11.7	1.1e-31	0.04	0.01	0.99	FALSE
30	GTEx	Cells Transformed fibroblasts	ERGIC2	0.12	0.03	enet	23	0.05	1.4e-04	11.96	-10.3	5.1e-25	-0.02	0.01	0.99	FALSE
31	GTEx	Cells Transformed fibroblasts	CCDC91	0.10	0.10	lasso	5	0.09	5.5e-07	-20.69	-21.5	2.4e-102	0.84	0.14	0.85	FALSE
32	GTEx	Cells Transformed fibroblasts	RP11-967K21.1	0.07	0.07	lasso	2	0.07	3.7e-06	-22.58	23.2	1.1e-118	-0.96	0.08	0.92	TRUE
33	GTEx	Cells Transformed fibroblasts	RP11-996F15.2	0.34	0.33	lasso	7	0.34	7.3e-26	11.96	11.6	2.5e-31	0.04	0.00	1.00	FALSE
34	GTEx	Colon Sigmoid	RP11-996F15.2	0.42	0.27	lasso	7	0.29	7.7e-11	11.96	11.7	1.9e-31	0.05	0.00	1.00	FALSE
35	GTEx	Colon Transverse	CCDC91	0.11	0.01	lasso	6	0.00	4.6e-01	-20.96	-19.3	2.7e-83	0.81	0.09	0.76	FALSE
36	GTEx	Colon Transverse	RP11-967K21.1	0.12	0.07	lasso	8	0.05	1.6e-03	8.87	11.5	1.3e-30	-0.57	0.19	0.72	FALSE
37	GTEx	Colon Transverse	RP11-996F15.2	0.31	0.32	lasso	1	0.31	3.5e-15	11.96	12.0	5.5e-33	0.04	0.00	1.00	FALSE
38	GTEx	Esophagus Gastroesophageal Junction	RP11-996F15.2	0.50	0.42	lasso	8	0.42	1.4e-16	11.96	11.8	2.6e-32	0.05	0.00	1.00	FALSE
39	GTEx	Esophagus Mucosa	MRPS35	0.18	0.00	enet	20	0.01	6.6e-02	0.53	10.1	7.5e-24	-0.37	0.06	0.48	FALSE
40	GTEx	Esophagus Mucosa	CCDC91	0.18	0.04	enet	36	0.03	3.1e-03	11.69	-15.8	4.7e-56	0.57	0.19	0.56	FALSE
41	GTEx	Esophagus Mucosa	RP11-996F15.2	0.39	0.43	lasso	7	0.45	6.2e-33	11.96	12.1	1.6e-33	0.05	0.00	1.00	FALSE
42	GTEx	Esophagus Muscularis	RP11-967K21.1	0.07	0.06	lasso	5	0.04	2.2e-03	8.88	10.2	1.2e-24	-0.58	0.26	0.27	FALSE
43	GTEx	Esophagus Muscularis	RP11-860B13.1	0.19	0.07	enet	24	0.06	2.1e-04	-0.85	-9.3	9.2e-21	0.40	0.32	0.58	FALSE
44	GTEx	Esophagus Muscularis	RP11-996F15.2	0.56	0.45	enet	31	0.47	1.3e-31	11.96	11.7	1.5e-31	0.02	0.00	1.00	FALSE
45	GTEx	Heart Atrial Appendage	CCDC91	0.10	0.06	lasso	8	0.04	4.4e-03	-20.69	-21.0	2.7e-98	0.84	0.06	0.87	FALSE
46	GTEx	Heart Atrial Appendage	RP11-967K21.1	0.08	0.09	lasso	1	0.08	2.3e-04	-22.58	22.6	7.1e-113	-0.92	0.06	0.88	FALSE
47	GTEx	Heart Atrial Appendage	RP11-283G6.5	0.27	-0.01	enet	8	0.02	4.5e-02	3.33	-5.1	2.8e-07	0.04	0.07	0.12	FALSE
48	GTEx	Heart Left Ventricle	IPO8	0.14	0.00	lasso	7	0.03	8.6e-03	-6.42	-5.4	8.3e-08	0.01	0.03	0.88	FALSE
49	GTEx	Lung	CCDC91	0.14	0.00	enet	33	0.06	1.5e-05	-8.40	-10.5	7.3e-26	0.37	0.27	0.12	FALSE
50	GTEx	Lung	IPO8	0.07	0.06	lasso	5	0.07	7.5e-06	4.22	-5.4	6.5e-08	0.00	0.10	0.90	FALSE
51	GTEx	Lung	RP11-996F15.2	0.50	0.46	lasso	5	0.46	1.9e-39	11.96	11.9	8.0e-33	0.04	0.00	1.00	FALSE
52	GTEx	Muscle Skeletal	RP11-967K21.1	0.04	0.01	lasso	9	0.00	2.9e-01	-20.96	20.5	4.3e-93	-0.88	0.12	0.61	FALSE
53	GTEx	Muscle Skeletal	RP11-996F15.2	0.24	0.26	lasso	11	0.25	9.3e-25	12.10	12.3	1.1e-34	0.05	0.00	1.00	FALSE
54	GTEx	Nerve Tibial	IPO8	0.21	0.16	lasso	6	0.15	1.3e-10	-6.47	-6.5	9.0e-11	-0.02	0.02	0.98	TRUE
55	GTEx	Nerve Tibial	RP11-996F15.2	0.52	0.53	lasso	5	0.56	3.3e-47	11.96	11.6	3.4e-31	0.05	0.00	1.00	FALSE
56	GTEx	Ovary	RP11-996F15.2	0.50	0.46	enet	22	0.54	1.1e-15	10.90	10.9	1.5e-27	0.06	0.01	0.99	FALSE
57	GTEx	Pancreas	RP11-996F15.2	0.56	0.46	enet	22	0.48	1.8e-22	11.96	12.2	1.9e-34	0.03	0.00	1.00	FALSE
58	GTEx	Pituitary	RP11-967K21.1	0.20	0.04	lasso	7	0.04	4.4e-02	10.37	15.7	1.5e-55	-0.64	0.06	0.54	FALSE
59	GTEx	Pituitary	RP11-996F15.2	0.54	0.42	lasso	8	0.32	7.7e-09	11.96	12.1	1.8e-33	0.05	0.00	1.00	FALSE
60	GTEx	Prostate	RP11-996F15.2	0.49	0.36	enet	32	0.39	6.0e-11	11.96	11.9	1.0e-32	0.04	0.00	1.00	FALSE
61	GTEx	Skin Not Sun Exposed Suprapubic	CCDC91	0.26	0.05	lasso	15	0.04	4.1e-03	-22.00	-22.0	2.7e-107	0.85	0.18	0.81	TRUE
62	GTEx	Skin Not Sun Exposed Suprapubic	TMTC1	0.21	0.00	enet	32	0.01	1.2e-01	0.43	5.1	2.6e-07	-0.01	0.09	0.33	FALSE
63	GTEx	Skin Not Sun Exposed Suprapubic	RP11-996F15.2	0.44	0.28	enet	55	0.28	1.1e-15	11.96	11.4	4.5e-30	0.02	0.00	1.00	FALSE
64	GTEx	Skin Sun Exposed Lower leg	CCDC91	0.09	0.01	enet	8	0.01	2.6e-02	-22.58	-22.1	6.4e-108	0.87	0.10	0.83	FALSE
65	GTEx	Skin Sun Exposed Lower leg	IPO8	0.23	0.08	lasso	10	0.13	1.1e-10	-6.50	-6.3	3.3e-10	0.00	0.03	0.97	FALSE
66	GTEx	Skin Sun Exposed Lower leg	RP11-996F15.2	0.50	0.48	enet	21	0.50	1.5e-47	12.10	12.1	1.9e-33	0.04	0.00	1.00	FALSE
67	GTEx	Small Intestine Terminal Ileum	RP11-996F15.2	0.60	0.51	lasso	5	0.46	7.1e-12	12.10	12.5	1.2e-35	0.04	0.00	1.00	FALSE
68	GTEx	Spleen	RP11-996F15.2	0.53	0.49	lasso	5	0.46	1.7e-13	12.10	11.9	8.4e-33	0.06	0.00	1.00	FALSE
69	GTEx	Stomach	RP11-996F15.2	0.35	0.41	lasso	3	0.40	1.4e-20	11.96	11.9	1.8e-32	0.03	0.00	1.00	FALSE
70	GTEx	Testis	RP11-996F15.2	0.28	0.35	lasso	2	0.37	2.7e-17	11.96	11.6	3.5e-31	0.03	0.00	1.00	FALSE
71	GTEx	Thyroid	CCDC91	0.15	0.12	enet	42	0.12	2.9e-09	-22.25	-16.7	1.2e-62	0.83	0.11	0.89	TRUE
72	GTEx	Thyroid	RP11-967K21.1	0.05	0.00	enet	7	0.00	2.8e-01	8.21	6.2	4.2e-10	-0.42	0.09	0.37	FALSE
73	GTEx	Thyroid	RP11-996F15.2	0.54	0.54	lasso	8	0.55	9.1e-50	12.10	12.1	6.1e-34	0.04	0.00	1.00	FALSE
74	GTEx	Uterus	RP11-996F15.2	0.37	0.08	enet	16	0.22	3.3e-05	11.96	9.1	7.7e-20	0.02	0.01	0.96	FALSE
75	GTEx	Vagina	RP11-996F15.2	0.44	0.31	enet	23	0.27	5.9e-07	12.10	11.0	4.6e-28	0.05	0.01	0.99	FALSE
76	GTEx	Whole Blood	RP11-996F15.2	0.20	0.18	enet	11	0.18	9.2e-17	11.96	12.2	5.4e-34	0.07	0.00	1.00	FALSE
77	METSIM	Adipose	FAR2	0.05	0.02	enet	10	0.03	6.2e-05	6.88	8.2	2.3e-16	0.08	0.96	0.03	FALSE
78	NTR	Blood	CCDC91	0.01	0.01	blup	648	0.00	9.0e-03	8.68	-16.6	1.1e-61	0.77	0.24	0.45	FALSE
79	ROSMAP	Brain Pre-frontal Cortex	FGFR1OP2	0.04	0.00	bslmm	525	0.00	7.9e-02	1.96	6.1	8.7e-10	-0.07	0.00	0.01	TRUE
80	ROSMAP	Brain Pre-frontal Cortex	DENND5B	0.19	0.09	lasso	6	0.15	2.4e-19	-6.08	-7.7	1.3e-14	0.01	0.36	0.64	TRUE
81	ROSMAP	Brain Pre-frontal Cortex	RP11-996F15.2	0.21	0.22	lasso	7	0.24	5.1e-30	11.96	11.7	8.1e-32	0.05	0.00	1.00	FALSE
82	The Cancer Genome Atlas	Breast Invasive Carcinoma	CCDC91	0.04	0.04	lasso	3	0.03	1.8e-06	-22.43	-22.4	2.4e-111	0.98	0.19	0.81	FALSE
83	The Cancer Genome Atlas	Breast Invasive Carcinoma	DENND5B	0.01	0.01	blup	101	0.01	1.2e-03	-4.82	-6.6	4.4e-11	0.02	0.05	0.15	FALSE
84	The Cancer Genome Atlas	Breast Invasive Carcinoma	ERGIC2	0.03	0.00	blup	62	0.02	2.6e-04	-3.82	-7.5	7.1e-14	0.00	0.03	0.52	FALSE
85	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC91	0.06	0.02	blup	174	0.04	2.9e-05	9.52	-18.8	6.8e-79	0.82	0.54	0.43	TRUE
86	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ERGIC2	0.04	0.03	lasso	2	0.03	1.3e-04	11.96	-11.8	2.3e-32	-0.03	0.01	0.99	FALSE
87	The Cancer Genome Atlas	Brain Lower Grade Glioma	ERGIC2	0.06	0.02	enet	9	0.04	4.8e-05	6.88	-9.5	1.7e-21	-0.08	0.01	0.90	FALSE
88	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C12orf72	0.11	0.00	blup	57	0.02	5.4e-02	2.64	7.0	2.2e-12	-0.10	0.01	0.24	FALSE
89	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SSPN	0.15	0.04	lasso	3	0.07	4.6e-04	5.66	-6.3	2.9e-10	-0.02	0.02	0.54	TRUE
90	The Cancer Genome Atlas	Lung Adenocarcinoma	CCDC91	0.09	0.01	blup	170	0.02	1.0e-03	-22.25	-19.1	2.9e-81	0.80	0.09	0.83	FALSE
91	The Cancer Genome Atlas	Lung Adenocarcinoma	IPO8	0.06	0.04	blup	58	0.04	1.5e-05	4.34	-5.8	8.8e-09	0.01	0.35	0.64	FALSE
92	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IPO8	0.04	0.03	blup	58	0.03	9.7e-05	4.22	-5.4	5.9e-08	0.00	0.30	0.54	FALSE
93	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CCDC91	0.09	0.11	lasso	2	0.12	2.3e-05	-22.79	-22.8	5.5e-115	1.00	0.05	0.93	FALSE
94	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCDC91	0.22	0.00	enet	16	0.04	2.5e-05	11.59	-12.7	4.8e-37	0.44	0.02	0.08	FALSE
95	The Cancer Genome Atlas	Prostate Adenocarcinoma	ERGIC2	0.05	0.02	lasso	4	0.05	3.3e-06	8.68	-6.8	8.5e-12	0.01	0.05	0.78	FALSE
96	The Cancer Genome Atlas	Thyroid Carcinoma	CCDC91	0.40	0.12	blup	175	0.14	4.9e-13	-22.06	-17.5	2.3e-68	0.65	1.00	0.00	FALSE
97	The Cancer Genome Atlas	Thyroid Carcinoma	DENND5B	0.08	0.04	enet	12	0.06	2.4e-06	7.00	-5.9	3.2e-09	0.05	0.02	0.98	FALSE
98	The Cancer Genome Atlas	Thyroid Carcinoma	ERGIC2	0.19	0.10	blup	62	0.11	1.1e-10	10.90	-11.4	5.9e-30	-0.04	0.01	0.99	FALSE