Hub : Genes

ABCC1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1240	0.0410	1.1e-03	0.003	0.015	0.032	0.019	0.009	1.3e-01	5.3e-03	8.7e-05	1.8e-03	2.6e-02
2	GTEx	Brain Caudate basal ganglia	0.3110	0.0960	9.7e-04	0.005	NA	0.094	NA	0.045	2.3e-01	NA	1.2e-03	NA	2.0e-02
3	GTEx	Cells Transformed fibroblasts	0.3150	0.0560	1.0e-11	0.134	NA	0.200	NA	0.190	3.1e-10	NA	5.8e-15	NA	3.4e-14
4	GTEx	Nerve Tibial	0.0777	0.0305	4.9e-03	0.011	NA	0.027	NA	0.016	5.1e-02	NA	4.8e-03	NA	2.6e-02
5	GTEx	Skin Sun Exposed Lower leg	0.1400	0.0420	8.2e-05	0.000	NA	0.067	NA	0.045	3.0e-01	NA	3.4e-06	NA	1.3e-04
6	METSIM	Adipose	0.0463	0.0193	2.0e-03	0.009	0.035	0.022	0.034	0.013	1.4e-02	4.4e-06	2.2e-04	7.0e-06	3.7e-03
7	NTR	Blood	0.0484	0.0144	4.5e-06	0.010	0.022	0.023	0.022	0.020	2.8e-04	6.7e-08	4.0e-08	6.5e-08	3.5e-07
8	ROSMAP	Brain Pre-frontal Cortex	0.0478	0.0223	1.6e-02	0.009	0.018	0.006	0.017	0.012	2.2e-02	1.9e-03	5.5e-02	2.3e-03	1.0e-02
9	TCGA	Thyroid Carcinoma	0.0730	0.0280	5.2e-04	0.071	0.040	0.051	NA	0.061	1.9e-07	7.6e-05	1.0e-05	NA	1.5e-06
10	TCGA	Uterine Corpus Endometrial Carcinoma	0.3220	0.1050	5.5e-03	-0.010	0.012	-0.010	NA	0.001	8.4e-01	1.4e-01	9.0e-01	NA	2.9e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	1.5	2.4	7.0	-2.6	-0.9	-1.8	-1.4	-2.0	1.2	-2.1	0.4	-0.8	0.7
Bipolar Disorder or Schizophrenia	0.7	1.8	4.3	-2.1	-1.7	-1.9	-0.8	-1.4	0.8	-1.5	-0.4	-0.7	1.0
Depressed Affect (Nagel 2018)	0.6	1.2	6.2	-2.5	-0.7	0.0	0.7	0.8	-0.4	-1.2	-0.3	-0.1	1.7
Depression (Nagel 2018)	0.4	0.6	1.9	-1.3	-1.4	-0.1	0.3	0.4	-0.0	-1.0	-0.4	-0.0	0.6
Intelligence (Savage-Jansen 2018)	0.8	2.4	13.5	-1.2	-0.3	-1.1	-2.4	-3.7	0.3	-0.1	1.2	0.2	-0.2
Neuroticism (Nagel 2018)	0.6	1.4	4.9	-2.2	-0.8	-0.2	0.7	0.7	0.2	-1.1	-1.1	0.0	2.2
Schizophrenia (2018)	0.2	0.5	1.8	-0.6	-1.4	-1.0	0.1	-0.1	0.1	-0.2	-0.8	-0.3	0.7
Schizophrenia vs Biploar Disorder	1.0	1.4	7.0	1.3	1.0	0.4	1.0	2.6	-0.6	1.4	-0.4	0.4	-0.5
Worry (Nagel 2018)	0.6	1.3	5.7	-1.0	-1.3	-0.2	0.7	0.4	0.1	-0.9	-1.7	0.1	2.4
Alzheimer’s Disease (in mother)	0.8	0.9	3.4	-1.5	-0.7	-1.9	-0.8	0.3	0.5	0.4	0.6	1.2	-0.1
Alzheimer’s Disease (in father)	1.1	1.2	3.1	-1.1	0.2	-1.4	-1.3	-0.1	1.8	-0.0	1.2	1.4	-0.3
Alzheimer’s Disease (including proxy)	1.1	1.6	5.2	-1.3	-0.0	-2.3	-1.0	0.6	1.4	0.8	1.1	1.8	-0.3
Crohns Disease (2017)	0.3	0.6	1.2	0.5	0.3	-1.1	-0.7	-0.7	-0.2	-1.0	0.8	1.1	1.0
Irritable Bowel Disease (IBD)	0.5	1.2	4.0	2.0	0.1	-1.5	-0.7	0.7	-0.7	0.8	-0.7	0.6	1.6
Ulcerative Colitis (UC)	1.1	2.0	5.0	2.2	0.2	-1.1	-0.3	1.6	-0.8	2.2	-1.6	-0.2	1.7
Major Depression (MDD)	1.4	1.7	8.9	0.5	-1.5	1.0	0.9	0.2	-0.9	0.8	-3.0	-1.1	-1.2
Reaction Time	0.6	1.2	3.2	-1.3	1.1	0.9	0.5	-1.6	-0.7	-1.3	-0.1	-1.8	-0.4
Verbal and Numeric Reasoning (VNR)	0.8	1.9	9.1	-0.4	-0.4	-1.4	-2.4	-3.0	0.5	0.5	0.5	1.1	0.3
Breast Cancer	0.7	1.6	6.3	0.8	0.8	0.5	0.5	2.1	-0.3	2.5	1.2	0.5	1.4
Ovarian Cancer	0.3	0.4	1.4	-0.4	-0.0	0.9	1.2	0.1	0.7	0.2	-0.0	-0.7	0.6
Prostate Cancer	0.7	1.0	2.8	-1.0	-1.2	-0.6	-0.6	-1.2	-1.2	0.4	-0.4	1.7	0.6
Age at First Birth	0.6	0.9	4.8	-0.3	-0.7	0.8	-0.3	-0.8	1.1	0.5	1.0	-0.6	-2.2
Bipolar Disorder (2011)	1.3	1.3	4.0	-1.7	-0.6	-1.6	-2.0	-1.5	0.6	-0.1	0.3	0.3	0.5
Body Mass Index (BMI) (2010)	1.1	1.4	3.1	1.0	-1.5	1.5	1.6	0.7	0.4	1.0	0.9	-1.8	-0.9
Coronary Artery Disease (CAD)	0.6	0.7	2.6	-0.2	-1.0	-0.0	-0.5	0.2	-1.5	1.6	0.1	-1.1	0.5
Crohns Disease (2012)	0.2	0.4	1.9	0.2	0.5	-1.4	-0.0	0.3	0.3	-0.0	0.3	0.1	1.1
Mean Putamen Volume	0.6	0.7	3.6	0.4	-0.5	-0.7	-0.7	0.3	1.9	0.7	0.9	0.2	0.9
Fasting Glucose	0.5	0.6	1.8	1.4	-1.1	0.1	0.0	0.3	-1.3	0.3	-0.7	0.5	0.9
HbA1C	0.4	0.4	1.2	0.2	1.0	0.1	-0.1	0.4	1.0	-0.5	0.3	1.1	0.8
HDL Cholesterol	0.4	0.6	1.6	0.5	-0.2	0.6	0.8	0.6	-0.9	-0.7	-1.3	-1.2	-0.3
LDL Cholesterol	0.6	0.9	4.0	-1.1	-0.6	0.9	1.0	-2.0	-0.2	0.3	0.1	-0.0	-1.4
Lupus	0.8	1.1	4.8	-0.7	0.3	2.2	1.6	0.2	-0.2	-0.6	0.1	-1.4	-1.0
Neuroticism (2016)	0.7	1.0	2.4	-1.0	0.6	1.4	1.6	0.6	-0.7	-0.3	-1.5	-0.6	0.2
Primary Biliary Cirrhosis	0.6	0.9	3.1	-0.3	-1.5	0.3	0.6	1.8	-0.5	0.9	-0.8	-0.3	-1.0
Rheumatoid Arthritis	0.9	1.2	4.7	-0.4	0.5	-1.0	-1.0	-0.8	-1.4	-0.3	1.5	-0.0	2.2
Schizophrenia (2014)	0.4	0.9	4.1	-0.7	-0.9	-2.0	-0.0	0.1	1.3	-0.1	-1.1	0.1	0.8
Triglycerides	0.4	0.6	2.0	-0.6	-0.8	-0.5	-0.8	-0.7	1.0	-0.1	0.3	1.4	-0.7
Type 2 Diabetes (T2D) (2012)	0.6	0.6	2.3	-0.1	1.5	0.9	0.5	-0.3	1.4	-0.0	1.0	0.2	-0.3
Ulcerative Colitis	1.2	1.8	5.3	1.1	-1.0	-1.2	-1.0	1.7	-0.4	1.2	-1.2	1.3	2.3
Blood Eosinophil Count	0.2	1.7	7.0	0.6	-0.3	0.1	-0.2	0.9	1.3	-0.6	2.2	2.6	-1.2
Blood Platelet Count	0.2	2.2	6.7	-2.2	-2.6	0.4	-0.5	-2.0	-0.8	-1.1	-1.7	0.1	-1.1
Blood Red Count	0.5	4.8	18.9	1.7	-2.0	-1.2	0.7	1.5	-0.9	1.9	-4.3	2.1	3.1
Blood White Count	0.2	1.4	3.8	1.9	1.0	-1.9	-0.8	0.0	-0.4	-0.6	0.3	1.9	1.0
Heel T-Score	0.4	3.4	13.0	-0.8	-3.0	0.4	-0.2	-1.1	-2.4	-1.7	-3.6	0.6	-0.6
BMI	0.2	1.1	3.1	1.1	0.5	-1.8	0.9	1.1	-0.1	0.3	-1.5	-1.5	0.5
Height	0.6	10.8	37.9	1.3	0.5	-4.5	-3.1	1.8	0.5	2.1	0.5	5.5	6.2
Waist Hip Ratio (WHR)	0.5	2.1	7.6	-1.0	-1.5	-0.4	0.6	-0.7	-0.4	0.2	-2.7	2.8	1.4
Systolic Blood Pressure	0.4	2.1	7.6	2.8	1.9	1.0	-0.3	-1.3	0.0	-1.2	0.0	0.6	-2.2
Smoking Status	0.4	0.9	2.5	-0.0	0.7	1.5	1.6	0.1	-0.1	0.0	1.3	-0.7	-1.1
Allergy or Eczema	0.4	1.0	5.0	-0.2	-2.2	0.5	0.5	-0.0	-1.2	1.3	0.5	-1.2	-0.1
Cardiovascular Disease	0.4	1.2	3.4	1.8	0.7	1.0	1.3	-0.2	0.7	-0.7	-1.0	0.4	-1.8
Hypothyroidism (self reported)	0.6	1.5	3.9	0.7	-0.9	-0.3	-1.0	-0.1	-0.8	1.7	-2.0	1.4	1.7
Respiratory disease	1.0	2.3	10.3	-0.6	0.3	-0.6	0.5	1.8	3.2	-0.1	2.5	-1.2	-0.6
Type 2 Diabetes (T2D) (2018)	1.4	2.7	9.6	0.9	-2.1	0.6	1.6	1.8	-0.6	1.5	-3.1	1.1	1.5
Lung FEV1/FVC ratio	0.1	0.7	1.7	-0.1	1.1	-0.4	-0.9	-1.2	-0.1	-0.3	1.2	1.3	0.5
Lung FVC	0.2	1.0	5.6	-0.7	-0.2	0.4	-0.2	-0.3	-1.1	2.4	-0.7	-1.4	-0.5
Neuroticism	0.5	1.2	4.0	-2.0	-0.0	-0.3	1.3	0.8	0.9	-1.5	-0.9	-0.4	1.1
Chronotype (morning person)	0.5	1.2	4.8	-0.1	0.8	-0.3	-1.0	0.2	2.2	0.4	2.1	0.0	-1.1
Hair Pigment	0.0	1.1	4.3	-0.7	-1.1	0.8	0.9	-0.6	-2.1	0.2	-1.3	0.9	0.9
Tanning	0.1	1.0	2.1	0.9	-0.9	1.3	-0.1	-1.3	-1.4	1.5	-1.2	0.0	-0.3
Hand grip strength (left)	0.5	1.2	4.9	-0.4	0.0	-2.2	-0.5	2.0	-0.1	0.4	-1.0	1.1	0.9
Number of treatments/medications taken	0.4	0.7	2.8	-0.3	-0.5	-0.3	1.0	1.2	1.7	0.7	0.9	0.4	-0.6
Average weekly spirits intake	1.1	1.3	3.7	0.7	-0.0	1.3	1.9	0.7	-1.9	0.8	-1.4	0.2	0.9
Sensitivity / hurt feelings	1.1	1.8	7.2	-2.7	-0.3	-1.6	-0.4	0.1	1.0	-2.2	-0.7	0.7	1.1
Frequency of depressed mood in last 2 weeks	0.5	0.7	3.6	-0.9	-1.9	-1.1	-0.1	-0.1	0.7	-1.0	0.1	0.3	0.5
Hearing difficulty/problems: Yes	0.2	0.4	2.4	-0.5	-1.6	0.1	0.1	0.1	0.3	0.4	0.4	0.6	0.5
Relative age of first facial hair	0.7	1.4	6.5	-0.8	-0.8	0.2	2.5	0.2	0.4	1.0	-0.7	-0.7	-2.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.9	-0.2	-0.5	0.4	-0.6	-1.1	-0.2	-0.6	0.0	1.4	0.9
Ever used hormone-replacement therapy (HRT)	0.5	0.7	3.9	0.3	-0.3	0.7	-0.1	-0.5	-2.0	0.8	-0.7	-0.2	0.9
Ever had hysterectomy (womb removed)	1.1	1.2	2.8	-1.7	1.4	1.5	-0.7	-1.2	-1.1	-0.6	1.1	0.4	0.5
Systolic blood pressure, automated reading	0.4	1.1	3.4	0.6	1.7	0.7	0.4	-1.1	0.3	-1.1	0.3	-1.3	-1.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.3	-0.3	-0.8	0.5	0.4	0.1	-0.1	-1.5	-0.1	1.5	-1.2
Angina	1.0	1.3	3.3	1.0	-0.7	-0.4	-1.0	-0.2	-1.6	1.2	-1.8	-0.4	1.6
Medication for hormone replacement therapy	0.8	0.9	2.2	0.5	-0.6	1.4	1.4	-0.1	-0.2	0.8	0.3	-1.2	-1.5
Vitamin and mineral supplements	1.3	1.7	9.7	0.0	2.0	0.7	0.2	0.3	0.7	-3.1	-0.4	-1.3	0.6
Supplements: Zinc	0.6	0.7	2.1	0.0	-0.9	-0.7	-0.6	0.5	1.0	-0.5	1.5	1.0	-0.7
Medication: Co-codamol	0.8	0.9	3.8	0.9	-0.9	-0.8	-0.3	-0.2	-1.4	1.1	0.5	0.1	2.0
Medication: Metformin	0.7	1.0	2.6	1.5	-1.4	0.8	0.3	1.4	-0.4	1.6	-0.0	-0.0	0.2
Diabetes (father)	1.1	1.3	4.0	0.6	-0.1	-1.7	-1.5	-0.7	-1.5	-0.3	-0.9	-0.3	2.0
Diabetes (mother)	0.9	1.1	4.1	1.9	0.8	-0.4	-1.2	-0.1	0.6	0.6	-2.0	0.8	0.3
Severe depression (siblings)	0.4	0.4	1.0	0.3	-1.0	-0.2	-0.6	0.3	0.1	0.7	-0.5	0.8	1.0
Pack years adult smoking proportion	0.4	0.7	1.6	-0.5	-0.5	-0.2	-0.5	0.9	1.2	1.2	0.5	0.5	1.3
Impedance of leg (right)	0.4	1.8	6.2	0.1	-1.1	1.3	1.4	2.5	0.9	-0.2	-0.0	2.5	0.1
Leg fat-free mass (left)	0.3	1.8	5.5	2.1	0.8	-2.3	-0.7	0.9	-0.1	1.6	-0.1	0.1	1.7
Trunk fat percentage	0.4	1.4	3.1	1.7	0.1	-1.8	-0.1	1.5	0.8	1.1	-0.9	1.2	1.3
Hand grip strength (right)	0.6	1.5	5.8	-0.9	-0.8	-1.3	0.5	2.4	-0.9	0.6	-2.2	0.2	-0.0
Townsend deprivation index at recruitment	1.1	1.5	6.2	-1.4	0.4	0.3	-0.1	-2.1	-0.7	-2.5	-1.1	-0.6	-0.2
Current tobacco smoking	0.6	1.0	2.7	-0.1	0.7	0.9	1.7	1.5	1.0	-0.3	0.8	-1.6	0.4
Average weekly fortified wine intake	0.5	0.6	3.8	-0.4	0.1	0.1	-0.3	-1.9	-0.3	-0.1	0.2	1.1	0.8
Maternal smoking around birth	0.9	1.3	5.9	-0.5	-1.0	-0.6	1.8	1.0	-0.5	0.8	0.0	-0.7	2.4
Fed-up feelings	0.6	1.1	2.1	-1.4	-0.7	1.2	1.5	0.8	-1.2	-1.2	-1.0	-0.1	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.6	-0.5	-1.3	-0.0	0.7	0.7	0.3	-0.9	-0.7	0.8	0.7
Relative age voice broke	0.9	1.4	6.2	-0.4	0.5	-0.5	-0.1	-2.3	0.8	-0.4	-0.7	0.5	-2.5
Taking other prescription medications	0.3	0.4	2.2	0.5	-1.5	-0.1	0.9	0.5	-0.0	0.2	-0.6	-0.4	0.4
Age when periods started (menarche)	0.9	2.1	9.4	-2.3	1.1	0.2	0.6	-0.4	1.7	-3.1	0.7	-0.5	-0.9
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.1	-0.9	0.7	0.4	-0.2	-0.7	0.5	-1.8	0.4	-0.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	2.9	0.5	-0.3	0.0	0.5	-0.0	-0.1	0.4	-1.7	-0.4	0.0
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.3	-0.6	0.5	-0.2	-1.1	-0.3	0.8	-0.6	0.5	0.1	-0.1
Qualifications: CSEs or equivalent	0.5	0.7	1.8	1.4	0.1	0.5	0.6	1.1	-0.4	1.0	0.8	-0.2	1.3
Serious illness, injury or assault to yourself	1.1	1.4	3.6	-1.1	-1.3	-1.1	-1.2	-1.9	-1.5	0.3	-1.0	-0.3	1.0
High blood pressure	0.6	1.6	6.7	1.6	0.3	1.3	1.9	0.4	0.9	0.2	-0.3	-0.7	-2.6
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.7	-0.0	-1.6	-0.0	0.5	-0.1	0.1	0.7	0.8	-0.7	-0.3
Multivitamins +/- minerals	1.4	1.7	8.6	0.7	-1.6	-0.9	-0.8	-0.4	-0.0	2.9	-0.2	1.6	-1.1
Stomach or abdominal pain in last month	0.8	1.0	2.7	1.3	-1.0	0.1	-0.1	0.8	-1.5	-0.6	-0.9	1.7	0.5
Supplements: Glucosamine	0.9	1.2	4.0	-0.5	-0.6	2.0	1.0	0.6	-0.2	1.9	-1.1	1.2	-0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	0.2	-0.7	-0.0	0.6	0.5	-0.3	-0.6	-0.2	0.1	0.7
Medication: Atenolol	0.7	0.9	4.9	1.4	-0.1	0.4	0.3	0.2	-1.4	-0.4	-2.2	-0.1	-0.2
Medication: Levothyroxine sodium	0.5	0.8	2.1	-0.1	-0.6	0.6	0.0	-1.4	-1.3	1.0	-0.8	-1.4	-0.4
Sitting height	0.3	2.0	6.7	2.1	0.7	-0.9	-0.6	0.9	-1.3	1.9	0.3	1.3	2.6
Chronic bronchitis/emphysema (father)	0.3	0.3	1.2	-0.5	-0.7	1.1	1.0	0.3	0.2	0.2	-0.2	0.0	-0.1
High blood pressure (mother)	0.5	0.8	2.3	0.6	1.3	-0.4	-0.8	-0.1	1.1	-0.6	1.5	0.9	-0.2
Body mass index (BMI)	0.2	0.8	2.9	0.6	1.1	-1.7	0.0	0.6	0.4	0.2	-0.6	-1.6	0.1
Impedance of leg (left)	0.3	1.6	6.6	-0.2	-1.1	1.2	1.2	1.8	1.0	-0.2	-0.6	2.6	0.1
Leg predicted mass (left)	0.3	1.6	4.9	2.2	0.7	-2.2	-0.7	0.9	-0.1	1.6	-0.0	0.1	1.6
Trunk fat mass	0.4	1.8	4.7	1.7	0.3	-2.2	-0.2	1.8	1.0	1.3	-0.7	1.2	1.6
Waist circumference	0.3	1.0	4.8	0.1	-0.4	-2.2	0.1	0.7	0.5	0.4	-1.5	0.5	1.4
Number of incorrect matches in round	0.8	1.3	6.0	-0.1	1.1	-0.1	1.0	-0.2	-0.5	-0.5	-2.5	-1.9	0.8
Past tobacco smoking	0.4	0.8	2.1	0.9	-0.0	-1.2	-1.5	1.1	1.0	0.4	-0.2	-0.2	1.0
Alcohol usually taken with meals	0.6	1.0	5.0	0.6	0.3	0.9	0.1	-0.6	-0.8	1.3	0.9	-0.8	-2.2
Nervous feelings	0.4	0.8	3.3	1.3	-0.1	-0.8	-0.7	-0.0	0.4	-0.2	-1.8	0.0	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.0	-0.4	-1.7	-1.5	0.8	1.6	0.3	-0.2	-1.5	-0.6	1.7
Hearing difficulty/problems with background noise	0.5	0.7	2.8	-0.4	-1.7	1.5	0.4	-0.1	-0.3	-0.7	-0.7	0.8	0.4
Hair/balding pattern: Pattern 2	0.9	1.1	3.3	-0.3	-0.7	-1.7	-1.6	-0.8	-0.4	-0.8	-0.1	0.6	1.8
Had menopause	0.7	0.9	3.4	-1.0	-0.3	1.4	1.0	1.3	0.2	0.2	-0.1	-1.8	0.3
Had other major operations	0.6	0.7	3.6	0.4	-1.1	-0.6	0.2	-1.1	-0.2	0.4	-1.9	0.2	-0.7
Forced vital capacity (FVC)	0.3	1.1	5.6	0.7	-0.9	-1.1	-0.4	0.8	0.3	2.4	0.1	1.2	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	4.5	0.9	-0.8	-0.4	0.4	0.6	-0.6	0.9	-2.1	0.3	1.0
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	3.6	0.3	0.2	-1.6	-1.3	0.3	1.4	-0.0	0.5	1.9	0.3
Qualifications: None of the above	0.7	1.4	3.5	-1.7	-0.0	1.3	1.1	-0.4	-1.6	-1.3	-1.9	-0.6	0.1
Financial difficulties in last 2 years	0.8	1.0	4.4	0.6	-0.1	-0.9	0.4	0.5	-0.1	1.0	-2.1	0.2	1.8
Mouth/teeth dental problems	0.5	0.7	2.7	1.1	0.5	0.9	0.6	-0.5	-0.8	0.2	0.0	-1.6	-1.0
Heart attack	1.0	1.2	4.5	1.0	-0.9	0.2	-0.2	0.7	-2.1	0.2	-1.3	1.0	1.6
Allergy	0.2	0.5	1.8	0.3	0.9	0.4	-0.1	-0.4	-1.1	-0.6	-1.3	0.2	0.2
Pain all over the body in last month	1.8	2.0	10.5	0.7	-0.2	2.1	3.2	1.5	-0.2	-1.0	-1.0	0.0	0.4
Diabetes (self-reported)	1.2	1.8	4.5	0.9	-1.4	1.1	1.0	1.4	-1.8	1.5	-2.1	0.5	1.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	3.6	0.9	-1.4	-0.8	-0.8	-0.1	1.2	1.9	0.7	0.5	0.5
Medication: Ramipril	0.9	1.1	6.0	0.3	-0.9	0.1	-0.1	-0.8	-2.4	0.2	-1.7	-0.8	-0.0
Medication: Simvastatin	0.6	0.9	4.0	0.8	0.0	-0.7	0.9	2.0	0.6	1.2	-0.3	0.8	1.1
Fluid intelligence score	0.5	0.9	5.1	0.5	-0.3	-0.8	-1.3	-2.3	0.2	0.6	1.1	0.3	0.0
Illnesses of siblings	0.6	0.9	4.6	0.8	0.4	-1.1	-0.4	1.0	-0.2	2.1	0.1	0.8	-0.5
Neuroticism score	0.5	1.1	3.2	-1.8	-0.5	-0.5	0.7	0.7	1.5	-1.5	-0.6	-0.2	1.1
Weight	0.3	1.7	6.4	1.6	0.8	-2.5	-0.5	1.5	0.5	1.3	-0.5	0.1	1.7
Impedance of arm (right)	0.7	3.2	20.6	1.2	-1.0	-0.4	-1.0	0.6	0.7	1.6	0.3	4.5	2.1
Arm fat percentage (right)	0.4	1.6	7.1	1.3	0.4	-2.7	-0.9	0.6	1.0	1.3	-0.4	1.1	1.2
Trunk fat-free mass	0.2	1.3	4.6	1.2	0.8	-2.1	-0.3	1.2	0.2	1.5	0.4	-0.7	1.5
Hip circumference	0.2	1.0	2.4	0.8	0.6	-1.4	0.7	1.6	1.1	1.1	0.2	-0.9	1.0
Time employed in main current job	0.5	0.6	2.5	0.2	-0.9	0.6	0.5	-0.8	-0.2	-1.1	-0.5	-0.2	-1.6
Alcohol intake versus 10 years previously	0.6	0.8	4.1	-1.3	-0.2	0.2	0.9	0.4	-0.2	-2.0	0.3	-1.1	-0.6
Father’s age at death	0.4	0.5	3.1	-0.8	-0.6	0.1	0.3	0.4	-0.1	0.3	0.5	-1.8	-0.4
Worrier / anxious feelings	1.1	2.1	6.4	-2.2	-2.5	1.0	1.2	0.2	0.5	-2.0	-1.3	0.2	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.4	-0.6	-0.7	0.4	-0.2	1.2	0.3	-1.0	0.9	0.7	0.8
Falls in the last year	1.1	1.5	5.9	0.2	-0.1	0.5	2.3	1.3	-0.1	-0.6	-0.4	-2.4	-0.8
Hair/balding pattern: Pattern 3	0.3	0.4	1.4	-0.3	0.0	0.7	0.3	1.0	-0.3	-0.6	-1.2	0.3	0.7
Number of live births	0.5	0.7	3.2	-0.2	-0.6	-0.2	1.1	-0.4	-0.5	1.0	-0.9	-1.8	-0.3
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.6	0.7	-0.3	-1.4	-0.7	0.3	0.6	1.9	0.5	1.1	0.2
Pulse rate	0.9	1.5	4.8	-0.1	-1.3	2.2	-0.1	-1.1	0.9	0.5	1.2	1.1	-1.8
Happiness	0.5	0.7	3.9	-0.3	-1.2	0.8	-0.2	0.4	0.3	0.3	2.0	-0.2	-0.4
Noisy workplace	0.7	0.8	2.3	-0.2	0.1	-1.5	-0.4	0.5	1.4	-1.0	-0.9	0.9	1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.7	5.7	-0.5	-0.0	-0.6	-2.4	-1.7	0.6	-1.1	2.1	-0.5	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	2.2	-0.1	0.2	1.0	-0.2	0.2	0.5	1.0	1.5	-0.5	1.2
Mouth/teeth dental problems: Dentures	0.4	0.6	1.3	-0.8	0.9	-0.4	-1.0	-0.3	0.9	-0.4	1.1	0.8	0.9
Asthma	0.9	1.8	10.0	-0.9	0.5	-0.6	-0.3	0.5	3.2	0.0	2.4	0.4	-0.3
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	5.8	-0.2	1.7	-1.1	-0.5	-0.9	1.9	-1.0	2.4	0.7	-0.1
Medication: Cholesterol lowering	1.1	1.7	4.5	1.9	1.1	0.7	1.5	2.1	0.8	0.7	1.1	-1.0	-1.2
Depression (self-reported)	0.4	0.5	1.3	0.4	-1.1	-0.6	1.1	0.3	-0.9	-0.2	-0.7	-0.3	0.1
Medication: Lansoprazole	1.7	2.0	4.5	1.3	-1.0	1.9	1.5	1.4	-1.6	-0.3	-2.1	-1.2	1.0
Prospective memory result	0.4	0.5	1.8	-0.8	0.2	-0.4	0.5	0.9	0.5	-1.4	0.4	-0.5	0.9
Lung cancer (father)	0.6	0.7	1.8	-1.0	-0.9	-1.4	-0.0	-1.0	0.5	-0.0	-1.1	-0.7	0.9
Illnesses of mother	0.3	0.4	3.3	0.7	1.8	0.1	0.0	-0.3	0.2	0.4	0.4	-0.2	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	4.4	0.5	-0.6	-0.1	-0.4	0.3	-0.1	2.1	-0.3	0.0	0.4
Pulse wave Arterial Stiffness index	0.1	0.1	0.6	-0.4	-0.3	0.0	-0.6	0.1	0.3	-0.1	-0.1	-0.5	0.8
Impedance of arm (left)	0.5	2.2	14.5	0.7	-1.3	0.8	0.0	1.0	0.8	1.3	0.1	3.8	1.2
Arm fat mass (right)	0.3	1.3	5.1	1.4	0.4	-2.2	-0.1	1.4	1.0	1.4	-0.2	0.2	1.0
Trunk predicted mass	0.2	1.4	4.6	1.3	0.8	-2.1	-0.3	1.2	0.2	1.7	0.4	-0.8	1.4
Standing height	0.4	4.0	10.8	2.1	-0.2	-1.6	-0.7	2.2	0.5	2.5	0.4	3.3	3.2
Length of working week for main job	0.4	0.5	2.0	0.4	-1.1	-0.5	-0.8	0.2	-0.7	0.2	-0.0	0.4	1.4
Exposure to tobacco smoke at home	0.7	0.8	3.9	-2.0	-0.3	0.1	1.4	-0.2	-0.1	0.9	-1.0	-0.0	-0.4
Breastfed as a baby	1.1	1.3	5.3	-0.3	0.2	0.3	-0.5	-1.7	-1.5	-1.0	0.2	-2.3	-1.3
Tense / ‘highly strung’	0.6	1.1	3.3	-1.4	0.3	-0.2	0.7	0.0	1.1	-1.8	-0.5	-0.2	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	3.7	-0.0	0.7	-1.1	-0.2	1.3	1.9	0.1	1.0	1.0	1.0
Hair/balding pattern: Pattern 4	0.6	1.5	7.2	2.7	0.8	-0.2	-0.5	-0.6	-0.4	1.8	1.1	1.6	-0.0
Birth weight of first child	0.8	1.5	8.3	0.2	-0.1	-0.6	1.7	2.9	1.4	0.9	0.8	0.2	-0.1
Peak expiratory flow (PEF)	0.4	0.9	3.1	-0.1	0.4	-0.9	-0.5	0.2	0.9	1.7	0.7	1.8	-0.5
Pulse wave reflection index	0.8	1.0	3.3	1.4	0.1	-1.1	-0.4	0.9	-0.3	-1.2	-1.0	-1.8	0.6
Ever highly irritable/argumentative for 2 days	0.9	1.1	4.5	0.5	-1.1	-0.9	-0.3	1.7	0.2	0.2	-1.0	0.9	2.1
Loud music exposure frequency	1.0	1.1	3.6	0.7	0.9	-1.6	-1.0	0.8	-0.1	-0.9	0.9	0.3	1.9
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	5.8	0.2	-0.9	-1.0	-2.4	-0.4	1.3	-0.1	1.1	0.9	2.1
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	4.6	-1.3	-0.8	-2.2	-1.3	0.2	-0.2	-1.0	-0.4	-0.0	1.6
Blood clot in the leg (DVT)	0.3	0.4	1.5	0.7	-0.1	-0.9	-0.9	-0.8	-0.0	1.2	0.0	0.3	0.4
Medication: Paracetamol	0.4	0.6	2.2	-0.3	-0.5	0.2	1.1	1.0	1.0	1.5	0.6	-0.2	-0.3
Headache pain in last month	1.4	2.4	7.9	-1.8	-0.6	-2.5	-1.3	0.3	2.8	-1.5	1.1	1.1	-0.4
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.1	-1.2	-1.1	-0.9	-1.5	-1.6	-0.5	0.1	-0.8	0.1	1.8
Glaucoma (self-reported)	1.0	1.2	2.3	-0.0	1.3	-1.2	-1.5	-0.6	0.3	-0.5	1.4	1.5	1.2
Gout (self-reported)	0.5	0.7	2.8	-0.7	0.1	0.1	-0.4	1.1	0.8	1.1	-0.0	1.7	-0.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.1	3.2	-0.1	-0.8	0.0	-0.5	0.2	-1.0	1.8	-1.8	-0.2	1.5
Medication: Amlodipine	1.6	2.2	4.2	-0.2	0.5	1.9	1.4	-1.9	-1.6	-1.2	-1.4	-2.0	-1.5
Medication: Ventolin 100micrograms inhaler	1.8	2.3	7.5	0.4	-0.4	-2.7	-2.0	-0.3	1.4	0.2	0.8	1.2	2.7
Birth weight	0.7	1.5	7.2	0.3	0.1	1.3	0.7	2.1	0.7	0.8	0.5	2.7	-0.2
Chronic bronchitis/emphysema (mother)	1.0	1.2	4.5	-0.1	-0.4	-1.6	-2.1	-0.5	0.5	-0.9	-0.1	1.5	1.2
High blood pressure (siblings)	0.6	0.8	2.3	-0.6	-0.0	0.2	0.4	-1.2	1.4	-1.5	-0.0	-1.1	-0.6
Forced vital capacity (FVC), Best measure	0.3	1.1	6.7	0.4	-1.0	0.2	0.5	1.5	-0.1	2.6	-0.2	-0.2	0.2
Body fat percentage	0.4	1.4	5.0	1.1	0.4	-2.2	-0.3	1.4	1.1	0.9	-0.9	1.0	1.3
Leg fat percentage (right)	0.3	1.2	5.8	0.5	0.5	-2.4	0.0	1.6	1.4	0.1	-0.8	-0.0	0.6
Arm fat-free mass (right)	0.2	1.2	2.7	1.2	0.7	-1.5	0.4	1.6	-0.1	1.2	-0.2	-1.5	1.1
Exposure to tobacco smoke outside home	2.9	3.9	13.2	-1.0	-1.4	-3.0	-1.3	0.5	1.3	0.2	-1.1	2.9	3.6
Comparative body size at age 10	0.5	1.3	4.5	1.1	0.2	0.2	0.2	-0.5	-2.1	0.6	-0.7	-1.6	-1.8
Number of full brothers	1.2	1.5	4.4	-0.0	-1.7	-0.4	2.1	1.5	-0.4	-0.5	-1.9	-0.2	1.4
Worry too long after embarrassment	0.3	0.4	1.5	-0.9	-0.0	0.2	1.0	0.5	1.2	-0.4	-0.2	-0.5	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.4	5.2	0.6	0.1	-2.3	-1.7	-0.5	-0.2	0.6	0.4	1.1	1.9
Wheeze or whistling in the chest in last year	1.1	2.0	6.6	0.3	-0.1	-2.2	-0.1	1.5	0.9	1.4	1.2	1.5	2.6
Number of children fathered	0.4	0.5	2.9	-0.4	-1.7	-0.6	0.3	0.4	0.2	-0.1	0.9	0.6	0.1
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	4.0	-0.1	-1.5	1.1	1.7	-0.6	-1.5	-0.6	-1.6	0.2	-2.0
Age at first live birth	1.1	1.9	5.1	1.4	1.0	1.1	1.4	0.4	1.1	2.3	1.8	-1.5	-1.0
Pulse wave peak to peak time	0.1	0.2	0.5	0.6	0.2	-0.1	0.7	0.3	-0.4	0.5	0.1	0.4	-0.3
Health satisfaction	0.8	1.1	2.2	1.2	-0.6	-0.5	-1.0	0.6	1.0	-0.9	1.2	1.3	1.5
Shortness of breath walking on level ground	1.1	1.3	3.5	-0.9	-0.7	-1.3	-1.2	-1.4	0.6	-1.6	-1.9	0.5	0.6
Qualifications: College or University degree	0.6	2.0	4.6	0.8	1.7	-1.5	-1.9	-1.4	1.8	0.2	2.1	1.0	0.2
Eye problems/disorders: None of the above	1.3	1.5	3.8	0.9	-1.2	1.3	0.6	-0.6	-1.8	0.8	-1.5	0.1	-2.0
Mouth/teeth dental problems: Loose teeth	0.6	0.8	3.5	-1.1	0.0	-0.9	0.3	1.0	1.9	-0.5	0.5	0.8	0.2
Emphysema/chronic bronchitis	0.8	0.9	4.4	-1.1	-0.1	-0.5	0.7	0.3	0.3	-2.1	0.9	-1.2	-0.2
Medication for pain relief, constipation, heartburn	0.4	0.7	4.3	0.4	-0.1	0.4	-0.7	-0.2	-2.1	0.0	-1.4	0.1	0.4
Neck or shoulder pain in last month	0.4	0.5	1.9	0.4	-0.6	-0.6	0.3	0.5	0.1	1.0	-0.9	-0.5	1.4
Medication: Blood pressure	0.9	1.6	7.7	0.4	1.1	1.5	1.7	0.8	0.6	-0.7	0.8	0.0	-2.8
Angina (self-reported)	1.0	1.4	2.9	1.3	-0.5	-0.2	-0.8	0.3	-1.6	1.6	-1.7	-0.4	1.6
Migraine (self-reported)	0.8	1.0	4.3	-2.1	0.4	0.1	0.9	1.1	0.6	-1.6	0.1	0.2	-0.6
Medication: Ibuprofen	1.1	1.3	3.9	0.1	1.3	-1.1	-0.6	-0.8	1.4	-1.4	2.0	0.7	0.7
Medication: Allopurinol	0.6	0.8	2.0	0.1	0.7	-0.5	-0.8	1.4	1.4	0.9	0.4	1.1	-0.6
Medication: Omeprazole	0.6	0.8	1.3	-0.8	-1.1	1.0	1.1	-0.6	-0.1	-0.1	-0.8	-1.1	-1.0
Medication: Seretide 50 evohaler	0.8	0.9	2.0	-0.4	0.2	-1.4	-1.2	-1.2	-0.7	0.6	1.1	-0.8	1.2
Mean time to correctly identify matches	0.6	1.2	4.8	-2.2	0.6	0.1	-0.6	-1.7	0.5	-1.1	0.6	-1.4	0.2
Heart disease (mother)	0.6	0.7	2.1	0.1	-1.3	-1.0	-1.4	-0.2	-0.5	1.1	-0.7	-0.3	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.2	-0.4	-0.2	-0.4	-0.0	-1.3	1.5	-1.0	0.5	0.9	-0.7
Whole body fat mass	0.4	1.7	5.7	1.4	0.6	-2.4	-0.1	1.7	0.9	1.3	-0.7	0.5	1.7
Leg fat mass (right)	0.4	1.5	6.3	1.1	0.8	-2.5	0.1	2.0	1.1	0.6	-0.7	0.2	1.1
Arm predicted mass (right)	0.2	1.2	2.6	1.5	0.4	-1.5	0.3	1.6	-0.1	1.1	-0.3	-1.5	1.1
Pulse rate, automated reading	2.3	7.4	29.0	-3.3	-0.7	2.8	1.5	0.0	5.4	-1.1	3.4	0.9	-3.1
Alcohol intake frequency.	0.7	1.5	4.3	-1.7	0.4	-1.5	-1.3	-0.8	0.4	-1.4	1.1	0.2	2.1
Comparative height size at age 10	0.7	4.0	12.5	2.9	-1.6	-0.6	-0.6	2.3	-0.3	2.8	-1.2	1.1	3.5
Number of full sisters	0.8	1.0	1.9	-1.2	-0.0	0.0	-1.2	-1.4	-1.4	-1.1	0.4	-1.3	0.0
Suffer from ‘nerves’	0.6	1.0	2.7	0.5	0.0	-1.6	-0.3	0.3	1.6	-0.7	-1.1	0.7	1.4
Overall health rating	0.4	0.8	2.3	-0.5	-0.6	-0.0	-0.3	0.5	0.9	-1.5	0.7	0.8	1.5
Chest pain or discomfort	0.6	0.9	2.3	0.6	-1.4	-0.2	0.1	-0.8	-0.6	-0.9	-0.6	1.5	1.5
Had major operations	0.5	0.5	2.7	-0.6	-0.8	-0.7	0.2	1.6	0.8	0.2	0.7	-0.3	0.1
Age at last live birth	1.3	1.9	8.5	2.9	-0.8	-0.0	0.7	-0.7	-0.3	2.7	0.7	-0.6	-0.6
Family relationship satisfaction	0.5	0.6	2.0	0.4	-1.0	-0.6	0.3	1.4	-0.6	-0.3	-0.2	-1.3	-0.7
Leg pain on walking	0.4	0.6	2.8	-0.1	-1.0	-0.8	-0.2	0.2	0.8	-1.7	0.1	0.7	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.0	1.0	-0.9	-0.8	-0.7	1.2	0.1	0.5	-0.1	1.4	1.1
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.8	-0.2	-0.5	0.6	0.9	1.7	-0.1	-0.0	-1.1	0.3	1.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.5	0.6	0.0	0.8	0.4	1.0	-0.2	0.8	-0.1	1.2	-1.0
Medication: Aspirin	0.2	0.3	0.6	0.0	-0.3	0.4	0.8	0.6	0.6	0.7	0.2	-0.6	-0.4
Supplements: Vitamin C	1.1	1.3	4.0	0.2	-0.1	1.5	0.7	1.1	0.6	1.4	2.0	-0.5	-1.5
Knee pain experienced in last month	0.6	0.9	3.5	-1.5	-1.0	-1.9	0.2	-0.3	0.2	0.1	-0.4	1.0	0.8
Hypertension (Self-reported)	0.6	1.6	7.7	1.8	0.2	1.4	1.6	-0.1	0.5	-0.0	-0.6	-0.7	-2.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.0	0.8	0.5	0.3	1.0	0.9	-1.0	0.9	-1.0	-0.5	-0.1
Illnesses of father: Heart disease	0.8	1.1	4.0	2.0	-1.2	-1.0	-1.4	-0.7	0.0	1.2	-0.3	0.8	0.3
Illnesses of siblings: Diabetes	1.3	1.6	6.2	-1.5	-1.3	1.5	-0.5	-0.2	-1.6	-2.5	-0.5	-0.4	-0.1
Smoking status: Previous	0.3	0.4	1.2	-0.6	-0.0	1.0	0.7	-0.5	-1.1	-0.0	0.3	0.5	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.7	1.8	0.3	-0.7	-0.1	0.4	-0.0	1.9	0.4	1.5	1.9
Whole body fat-free mass	0.3	1.6	5.5	1.7	0.7	-2.3	-0.5	1.0	-0.0	1.6	-0.0	-0.5	1.6
Leg fat-free mass (right)	0.3	1.7	5.2	2.1	0.8	-2.3	-1.0	0.4	-0.2	1.7	-0.3	0.1	1.6
Arm fat percentage (left)	0.3	1.0	4.6	0.9	0.3	-2.1	-0.4	0.8	1.2	0.9	-0.4	0.8	0.9
Average weekly red wine intake	0.4	0.6	2.8	0.3	1.1	0.5	-0.3	-0.0	-0.2	-1.7	0.0	0.9	-1.1
Handedness (chirality/laterality): Left-handed	0.7	0.8	3.7	-1.4	0.4	-1.0	-0.8	-0.3	-0.4	-1.9	0.4	-0.2	-0.2
Mood swings	0.4	0.8	4.4	-2.1	0.1	-0.0	-0.1	0.2	0.4	-1.3	0.3	0.7	1.1
Loneliness, isolation	0.7	1.0	2.0	-1.4	-1.1	-1.2	-0.1	0.2	0.6	-1.4	-0.5	-1.4	0.7
Long-standing illness, disability or infirmity	0.4	0.6	2.3	0.7	-1.0	-0.0	-0.7	0.4	0.1	0.8	0.4	1.1	1.5
Ever had bowel cancer screening	0.8	0.9	3.2	-1.6	-0.3	0.3	0.4	-0.4	-0.5	-0.5	1.5	-1.8	-0.3
Diabetes diagnosed by doctor	1.0	1.7	3.8	1.1	-1.6	0.9	0.4	1.0	-1.9	1.4	-2.0	0.8	1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	5.6	0.7	-2.4	0.9	0.9	0.1	-1.7	2.0	-1.0	0.2	-0.7
Friendships satisfaction	1.3	1.6	6.2	0.9	1.3	-0.7	-0.4	1.3	1.6	-0.4	2.5	-0.9	-1.1
Qualifications: nursing, teaching	1.8	2.8	14.3	0.7	-1.2	-1.4	-2.2	0.1	-1.0	1.1	0.5	1.6	3.8
Commuting to job workplace: Walk	0.9	0.9	2.8	1.4	1.0	-0.4	0.5	1.4	-0.1	1.7	-1.0	0.0	0.3
Eye problems/disorders: Cataract	0.8	0.9	2.4	0.3	-1.4	-0.8	0.7	1.2	1.4	0.1	-0.3	-0.5	1.6
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.5	1.3	-0.6	0.3	0.3	-0.3	0.5	0.6	-1.2	1.6	-1.1
Medication for cholesterol	0.1	0.2	0.7	-0.3	0.2	0.2	-0.3	0.7	0.1	-0.3	0.8	-0.3	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.8	5.4	1.4	1.1	0.2	-0.2	2.3	1.9	2.0	1.1	0.7	0.4
Back pain experienced in last month	0.6	0.8	1.8	0.3	-1.0	-0.3	-0.7	-0.6	-1.3	1.1	-1.2	-0.2	1.2
Mineral and other dietary supplements	1.4	1.9	6.2	0.2	2.1	-1.4	-0.9	-0.9	1.3	-2.5	0.7	-1.2	-1.0
Breast cancer (self-reported)	0.3	0.3	1.2	-0.7	0.0	0.7	0.5	-0.5	-0.0	-0.8	-0.3	-0.2	-1.1
Asthma (self-reported)	0.9	1.8	10.2	-1.0	0.5	-0.8	-0.1	0.8	3.2	0.3	2.2	0.2	-0.2
Osteoporosis (self-reported)	0.5	0.7	1.6	-0.6	0.7	-0.5	-0.8	-0.2	1.3	-0.4	1.2	1.1	-0.6
Osteoarthritis (self-reported)	0.4	0.5	1.7	1.0	-0.0	-0.1	-0.6	0.8	0.2	0.9	0.4	0.6	1.3
Medication: Aspirin	0.5	0.7	1.4	0.4	-0.4	0.7	1.1	1.2	0.5	1.0	0.5	-1.2	-0.5
Medication: Gliclazide	0.3	0.3	1.7	0.1	-1.3	1.1	0.1	-0.4	0.1	0.1	-0.5	0.1	-0.1
Illnesses of father: None of the above (group 1)	0.6	0.8	2.6	-1.1	0.9	0.5	1.0	1.0	-0.8	0.5	-0.3	-1.6	-0.3
Smoking status: Current	0.6	0.9	3.0	-0.1	0.7	0.8	1.7	1.0	0.8	-0.4	0.9	-1.6	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	4.9	-0.9	-0.0	0.7	0.3	-0.2	-0.9	2.2	-0.3	-0.3	-0.7
Whole body water mass	0.3	1.5	5.5	1.7	0.6	-2.4	-0.6	0.9	-0.0	1.6	0.0	-0.6	1.7
Leg predicted mass (right)	0.3	1.7	4.9	2.1	0.8	-2.2	-1.0	0.4	-0.2	1.7	-0.2	0.1	1.6
Arm fat mass (left)	0.3	1.1	4.8	1.2	0.3	-2.2	-0.1	1.3	0.8	1.2	-0.4	-0.0	1.0
Number of self-reported non-cancer illnesses	0.4	0.6	3.1	0.0	-1.8	0.1	0.8	1.2	0.7	0.2	-0.1	0.6	0.1
Average weekly champagne plus white wine intake	0.5	0.6	1.7	-0.4	0.5	1.0	0.6	-0.1	1.1	-0.7	1.0	-0.1	-1.3
Miserableness	0.7	1.3	3.8	-2.0	-0.5	1.1	1.8	0.8	-0.3	-1.5	-0.1	-0.6	-0.9
Guilty feelings	0.1	0.2	1.1	0.2	0.4	0.2	-0.1	0.6	0.1	-0.2	0.0	1.1	0.2
Wears glasses or contact lenses	0.9	1.0	2.9	-1.4	0.5	0.2	-0.7	-0.7	0.0	-1.6	1.1	1.7	-0.1
Ever taken oral contraceptive pill	0.8	0.9	4.3	0.7	-0.4	0.7	-0.3	-0.7	-0.5	1.4	0.5	-0.7	-2.1
Hearing aid user	0.4	0.5	2.0	-0.3	0.1	-0.3	0.1	0.7	0.7	-0.4	1.4	0.2	-1.1
Mother’s age at death	0.5	0.6	2.6	-1.1	-1.6	-0.3	-0.1	0.6	0.8	-0.0	0.7	-0.5	0.4
Financial situation satisfaction	0.4	0.5	2.6	0.5	-0.2	-0.4	-0.1	1.3	0.0	-0.2	0.4	0.7	1.6
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.0	1.0	-1.5	-0.6	0.9	1.6	-0.6	1.7	-1.1	-0.2	1.0
Commuting to job workplace: Public transport	0.5	0.6	1.8	-0.3	0.5	-0.3	-0.4	0.8	1.3	-0.6	0.6	1.3	-1.0
Eye problems/disorders: Glaucoma	0.7	0.9	3.0	-0.1	1.7	-1.1	-1.0	-0.7	0.3	-0.3	1.3	0.6	0.8
Medication: Blood pressure	0.5	1.0	3.4	1.5	0.1	0.7	1.1	-0.5	-1.1	-0.1	-1.9	-0.1	-0.9
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.5	-1.0	0.5	-0.3	0.8	-0.2	0.5	-1.2	-0.6	0.2	1.1
Supplements: Fish oil (including cod liver oil)	1.5	2.0	8.8	0.6	-1.2	1.3	0.9	1.5	-1.8	3.0	-0.3	0.2	0.9
High cholesterol (Self-reported)	0.5	0.9	2.8	0.7	-1.0	1.3	1.7	1.1	0.0	0.0	-0.5	1.2	-0.7
Medication: Bendroflumethiazide	1.0	1.5	4.9	0.4	1.2	1.5	1.9	1.0	0.1	-1.2	0.5	-0.1	-2.2
Medication: Paracetamol	0.1	0.2	0.7	-0.5	-0.6	0.1	0.6	0.2	0.6	0.9	0.2	-0.1	0.0
Medication: Lisinopril	1.6	2.1	6.2	1.1	-0.7	2.5	2.5	1.6	-0.1	-0.1	0.8	-0.1	-1.8
Medication: Atorvastatin	0.2	0.3	1.3	0.2	-0.5	0.0	0.2	0.2	-0.7	1.1	-0.5	0.1	0.7
Illnesses of father: High blood pressure	0.7	0.9	3.0	0.3	0.0	0.2	-0.5	-1.4	0.8	-1.6	0.5	1.7	0.2
Alcohol drinker status: Never	0.5	0.6	4.0	-0.1	-0.7	-0.6	-0.6	0.2	0.5	-0.2	0.3	-0.1	2.0
Ever smoked	0.6	1.0	4.5	-0.6	0.5	1.3	2.1	-0.3	0.2	-0.8	0.2	-0.5	-1.4
Basal metabolic rate	0.3	1.7	6.1	1.8	0.8	-2.5	-0.4	1.2	0.1	1.6	-0.2	-0.4	1.6
Leg fat percentage (left)	0.3	1.1	5.5	0.2	0.5	-2.4	-0.2	1.0	1.5	-0.0	-1.1	-0.2	0.6
Arm fat-free mass (left)	0.3	1.7	6.2	1.5	0.7	-2.5	-0.7	1.0	-0.4	1.4	-0.5	-1.0	1.9
Number of operations (self-reported)	1.0	1.5	4.2	-0.3	-1.7	-2.1	-1.0	-0.8	-0.5	0.7	-1.3	1.4	1.3
Average weekly beer plus cider intake	1.0	1.5	3.7	-1.1	-1.6	-0.6	-0.7	-1.8	-0.9	-1.6	-1.9	-0.3	0.7
Irritability	0.8	1.3	7.6	-0.5	1.2	-0.4	-0.5	0.8	2.8	-0.0	1.1	1.2	0.2
Risk taking	0.7	1.0	3.4	1.8	0.6	-1.7	-0.7	0.4	0.2	1.2	-1.0	-0.2	-0.0
Ever had prostate specific antigen (PSA) test	0.9	1.1	4.0	-0.4	-1.3	-0.4	0.9	0.1	-0.2	0.4	-0.8	-2.0	-1.8
Fractured/broken bones in last 5 years	0.8	1.0	2.0	-1.1	0.9	-0.2	-0.4	-0.2	1.1	-1.4	1.4	-1.4	-0.9
Age started oral contraceptive pill	0.3	0.4	1.1	-0.8	0.5	0.5	-0.8	-1.0	0.2	-0.0	0.4	-0.9	0.6
Diastolic blood pressure, automated reading	1.2	3.6	11.8	-0.1	3.2	-0.4	0.5	-0.3	3.4	-1.0	2.0	-0.8	-2.7
Ever depressed for a whole week	0.4	0.5	2.1	0.3	-0.3	-0.5	0.6	0.7	0.7	-1.0	0.1	1.4	-0.0
Unable to work because of sickness or disability	1.2	1.5	7.6	-0.5	-2.8	-1.3	-1.0	-0.6	-0.3	0.4	-1.2	0.7	1.6
Commuting to job workplace: Cycle	0.8	1.0	2.8	1.2	-0.7	-0.1	0.2	-1.3	-0.1	1.7	-0.9	-1.5	-0.6
Myopia	0.5	0.7	1.8	1.1	-1.4	0.1	-0.6	-1.2	-1.2	0.2	-0.0	-0.6	-0.3
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.0	-1.4	-0.5	-1.2	-1.6	-0.7	-0.4	-0.3	0.4	0.5	1.7
Cholesterol lowering medication	0.9	1.4	4.4	-0.2	-1.6	-1.8	-0.6	-0.1	0.3	0.6	-0.3	1.6	2.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.6	0.4	-0.7	0.6	1.3	0.5	0.0	0.7	-1.2	-0.9	-0.8
Pain experienced in last month	0.8	1.3	4.8	0.7	1.3	0.9	-1.2	-2.2	-1.7	-0.6	-0.1	-0.7	-0.7
Supplements: Calcium	1.8	1.9	4.5	-0.8	1.0	-1.0	-2.1	-1.9	1.4	-1.5	2.1	0.4	-0.1
Basal cell carcinoma (self-reported)	1.6	1.9	6.6	2.6	-0.1	0.5	1.3	1.3	-1.6	1.3	-1.9	0.7	-0.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	5.2	0.7	-1.1	0.2	-0.2	0.6	-2.3	0.0	-1.3	1.0	1.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.5	0.5	-0.3	-0.8	-0.8	-0.8	-0.1	1.2	-0.2	-0.1	0.4
Heart disease (siblings)	0.5	0.6	2.3	0.6	-0.5	0.8	0.9	1.5	-0.1	-0.3	-0.8	-0.2	0.9
Alcohol drinker status: Previous	0.7	0.8	3.3	-0.7	0.6	-1.1	-0.9	0.0	1.0	0.3	1.8	1.0	-0.5
Pack years of smoking	0.4	0.6	2.1	-0.8	-1.1	-0.1	-0.5	0.7	0.6	1.1	0.2	0.2	1.5
Impedance of whole body	0.4	2.0	11.4	0.5	-1.3	1.3	0.7	1.5	0.5	0.7	-0.5	3.4	0.9
Leg fat mass (left)	0.4	1.4	5.8	1.1	0.8	-2.4	0.1	1.8	1.2	0.6	-0.8	0.2	1.1
Arm predicted mass (left)	0.3	1.6	6.4	1.3	0.6	-2.5	-0.6	1.1	0.1	1.3	-0.2	-1.0	1.7