TWAS hub - ABCC6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.1660	0.0632	5.6e-03	0.032	NA	0.057	NA	0.066	2.5e-02	NA	4.2e-03	NA	2.2e-03
2	GTEx	Artery Aorta	0.1420	0.0640	5.4e-03	0.117	NA	0.134	NA	0.112	5.4e-07	NA	7.6e-08	NA	9.9e-07
3	GTEx	Artery Tibial	0.1897	0.0496	4.3e-06	0.062	NA	0.184	NA	0.122	1.4e-05	NA	2.3e-14	NA	8.1e-10
4	GTEx	Heart Atrial Appendage	0.2760	0.0910	4.7e-03	0.035	NA	0.085	NA	0.077	1.1e-02	NA	1.2e-04	NA	2.4e-04
5	GTEx	Muscle Skeletal	0.1727	0.0447	3.4e-07	0.081	NA	0.165	NA	0.109	2.3e-08	NA	5.8e-16	NA	7.8e-11
6	GTEx	Nerve Tibial	0.2838	0.0741	3.7e-07	0.127	NA	0.121	NA	0.118	3.0e-09	NA	6.9e-09	NA	1.1e-08
7	GTEx	Thyroid	0.1590	0.0470	2.8e-05	0.092	NA	0.192	NA	0.192	1.6e-07	NA	1.2e-14	NA	1.2e-14
8	ROSMAP	Brain Pre-frontal Cortex	0.1070	0.0364	3.7e-04	0.032	0.033	0.059	0.043	0.054	5.4e-05	3.6e-05	4.0e-08	3e-06	1.7e-07
9	TCGA	Breast Invasive Carcinoma	0.1014	0.0437	3.6e-09	0.024	0.050	0.066	NA	0.041	9.3e-06	1.7e-10	1.7e-13	NA	7.2e-09
10	TCGA	Colon Adenocarcinoma	0.1480	0.0670	1.7e-03	0.011	0.044	0.035	NA	0.006	7.1e-02	1.5e-03	4.2e-03	NA	1.4e-01
11	TCGA	Brain Lower Grade Glioma	0.0501	0.0235	9.9e-04	0.035	0.031	0.020	NA	0.027	7.5e-05	1.9e-04	2.3e-03	NA	3.8e-04
12	TCGA	Prostate Adenocarcinoma	0.1639	0.0705	1.8e-07	0.043	0.089	0.160	NA	0.079	2.3e-05	1.4e-09	1.8e-16	NA	1.2e-08
13	TCGA	Stomach Adenocarcinoma	0.1310	0.0520	1.8e-04	0.077	0.069	0.058	NA	0.059	3.2e-06	1.1e-05	5.0e-05	NA	4.1e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Basal cell carcinoma (self-reported)	5.6	6.7	14.3	-2.0	-2.6	-2.7	-1.3	-2.0	-3.0	-2.4	-2.6	-3.0	-2.8	-2.6	-3.8	-1.9
Medication: Bendroflumethiazide	4.6	7.0	16.8	-3.0	-1.7	-3.0	-1.5	-1.8	-1.9	-2.4	-3.1	-2.8	-4.1	-3.2	-2.2	-2.3
Diabetes (father)	4.3	5.4	12.3	-2.3	-1.9	-1.5	-2.4	-3.5	-1.9	-3.1	-2.1	-2.2	-2.2	-1.9	-2.5	-1.9
Mean Putamen Volume	4.2	4.8	8.9	-1.8	-1.2	-2.2	-1.6	-2.2	-2.6	-2.6	-0.4	-2.7	-2.9	-2.2	-3.0	-1.6
Average weekly champagne plus white wine intake	4.2	5.8	9.6	-1.8	-2.3	-3.1	-2.4	-2.7	-2.7	-2.4	-1.6	-2.8	-2.2	-2.0	-2.9	-1.6
Birth weight of first child	4.1	7.5	13.9	2.4	3.4	3.1	2.3	3.0	2.6	3.7	1.9	2.4	2.7	1.4	3.3	2.4
Illnesses of siblings	3.8	5.3	11.7	1.6	1.5	1.6	0.9	3.2	3.4	2.9	1.5	2.7	1.7	1.8	3.2	1.9
Fed-up feelings	3.4	6.2	13.3	-2.5	-1.1	-2.3	-2.1	-2.6	-2.4	-1.4	-3.7	-3.0	-2.8	-3.2	-2.6	-1.7
Financial difficulties in last 2 years	3.2	4.3	5.9	-2.2	-2.3	-1.8	-1.9	-1.8	-2.2	-1.4	-2.3	-2.4	-2.0	-2.0	-2.4	-2.0
Lung cancer (father)	3.2	3.8	9.7	1.5	1.1	2.0	2.6	1.2	1.5	1.5	1.9	1.8	2.3	3.1	2.0	1.9
Number of full sisters	3.2	3.8	11.1	-1.8	-2.2	-1.5	-3.3	-2.7	-2.2	-1.8	-1.5	-1.7	-1.3	-1.5	-1.4	-1.4
Illnesses of father: None of the above (group 1)	3.2	3.9	6.7	1.2	2.0	2.0	1.4	2.5	1.7	2.0	1.4	2.3	2.6	1.2	2.6	2.2
Ever unenthusiastic/disinterested for a whole week	3.1	3.8	9.2	-1.4	-1.3	-2.1	-2.0	-3.0	-3.0	-1.3	-0.7	-2.1	-2.1	-1.6	-1.9	-1.4
Depression (self-reported)	2.9	3.5	9.4	-2.2	-0.8	-1.8	-3.1	-1.7	-1.6	-1.4	-2.3	-2.2	-1.9	-2.1	-1.5	-0.4
Ulcerative Colitis	2.7	3.9	7.2	-2.7	-1.4	-2.0	-2.2	-2.5	-1.9	-1.6	-1.7	-1.9	-2.5	-2.3	-1.6	-0.9
Frequency of tenseness / restlessness in last 2 weeks	2.7	4.2	7.6	-1.7	-1.9	-2.2	-2.4	-2.0	-2.8	-1.2	-2.3	-1.5	-2.4	-2.4	-2.0	-1.4
Pulse rate	2.7	4.5	11.0	-2.0	-1.5	-1.5	0.8	0.1	-1.0	-2.2	-2.4	-3.2	-2.6	-2.7	-3.3	-1.5
Depressed Affect (Nagel 2018)	2.6	5.5	15.1	-2.2	-0.5	-2.2	-1.2	-2.2	-2.3	-2.0	-3.9	-3.1	-2.4	-2.4	-3.0	-0.6
Medication: Atenolol	2.5	3.1	5.4	-2.2	-1.1	-1.7	-1.0	-2.3	-2.2	-1.5	-1.5	-1.4	-1.6	-1.8	-1.8	-2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.5	2.9	8.9	2.5	1.2	1.9	1.0	2.1	1.0	3.0	2.1	1.0	1.8	0.6	1.2	0.9
Fasting Glucose	2.4	2.8	9.9	0.7	1.9	3.1	0.6	2.3	1.3	0.8	1.3	0.8	1.9	1.7	1.4	2.0
High blood pressure (mother)	2.4	3.3	5.8	-1.2	-1.2	-2.4	-2.3	-2.4	-1.1	-0.9	-1.6	-2.4	-2.3	-2.4	-1.4	-0.2
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.9	7.7	-2.3	-1.0	-1.8	-2.8	-2.6	-1.0	-0.9	-2.6	-1.7	-2.5	-2.1	-1.2	-1.8
Miserableness	2.4	4.1	11.6	-2.2	-0.8	-2.6	-1.2	-2.4	-1.5	-1.8	-3.4	-1.9	-2.3	-2.0	-1.7	-0.8
HbA1C	2.3	2.5	7.1	1.4	0.8	0.2	0.9	0.1	0.6	2.4	0.8	1.6	2.0	2.0	2.7	2.2
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	6.7	0.0	-1.8	-1.7	-0.2	-1.2	-2.6	-0.9	-0.8	-1.7	-1.7	-0.8	-1.8	-2.4
Illnesses of father: High blood pressure	2.3	2.9	6.2	-1.4	-1.1	-1.5	-0.8	-2.5	-1.8	-2.0	-1.1	-2.5	-2.2	-1.1	-2.0	-0.8
Birth weight	2.2	4.8	7.9	2.7	1.6	1.6	2.6	2.1	2.1	2.8	1.1	2.3	1.8	1.9	2.8	2.1
Mouth/teeth dental problems: Loose teeth	2.2	2.6	5.8	2.0	1.8	1.4	1.0	1.6	-0.1	1.2	2.2	2.4	1.7	1.6	1.3	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.2	2.6	8.0	-1.6	-1.1	-1.6	0.8	-0.6	-0.4	-1.5	-2.0	-1.8	-2.8	-1.1	-2.0	-1.8
Schizophrenia (2014)	2.1	4.6	12.8	1.4	2.4	1.9	3.6	2.2	2.1	2.1	0.9	1.9	2.0	1.9	2.5	2.0
Number of children fathered	2.1	2.4	5.7	2.0	1.5	2.0	1.4	2.4	2.1	1.6	1.0	1.3	1.2	0.9	1.1	1.0
Mother’s age at death	2.0	2.5	5.5	0.6	2.3	1.9	0.6	2.4	2.2	1.2	0.8	2.2	1.1	1.0	1.7	0.9
Schizophrenia vs Biploar Disorder	1.9	2.5	6.4	1.4	2.2	2.5	1.2	2.0	2.0	0.6	2.0	1.0	1.4	0.7	0.6	1.4
Relative age of first facial hair	1.9	3.9	11.7	2.7	2.5	0.8	3.4	1.0	1.8	2.1	-0.2	1.5	2.2	2.3	1.5	0.8
Shortness of breath walking on level ground	1.9	2.2	8.4	-1.7	-0.2	-1.2	-1.6	-1.3	-1.8	-2.9	-0.8	-0.7	-0.6	0.4	-2.5	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	4.0	9.9	1.9	1.5	2.4	0.7	2.7	3.1	1.7	1.6	1.9	2.4	1.7	1.8	1.6
Hair/balding pattern: Pattern 2	1.8	2.3	5.7	-2.4	-0.6	-0.8	-1.5	-1.9	-1.7	-1.9	-1.4	-1.4	-1.3	-0.7	-1.6	-1.4
Had other major operations	1.8	2.2	5.9	0.9	1.0	0.6	1.1	1.7	2.2	1.2	0.9	2.4	1.4	1.7	1.9	1.0
Mood swings	1.8	3.2	6.0	-1.8	-1.7	-2.5	-2.1	-2.0	-1.6	-0.9	-2.3	-1.4	-1.9	-1.9	-1.2	-1.2
Pain type(s) experienced in last month: Hip pain	1.8	2.3	6.1	-1.3	-0.8	-1.5	-1.0	-2.2	-1.5	-2.0	-2.5	-1.3	-0.7	0.0	-1.8	-1.3
High blood pressure (siblings)	1.7	2.4	6.3	-1.3	-0.9	-1.8	-0.5	-2.5	-1.4	-2.5	-0.8	-1.4	-1.3	-1.6	-1.9	-0.9
Hypothyroidism (self reported)	1.6	3.7	12.0	-2.7	-1.6	-2.8	-2.3	-1.5	-0.7	-0.1	-3.5	-0.3	-1.0	-2.6	0.1	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	3.8	-0.9	-1.0	-1.4	-1.5	-1.5	-1.9	-0.8	-1.6	-1.6	-1.7	-1.4	-1.8	-1.5
Medication: Simvastatin	1.6	2.3	5.3	-1.3	-1.1	-1.3	-0.2	-1.4	-2.0	-1.4	-1.8	-1.8	-1.6	-1.6	-2.3	-1.1
Forced vital capacity (FVC), Best measure	1.6	5.9	10.7	2.7	2.4	2.7	1.2	2.8	3.3	2.8	2.6	2.0	2.5	1.7	2.6	1.7
Depression (Nagel 2018)	1.5	2.2	6.8	-0.9	-0.1	-1.2	-1.1	-1.2	-1.7	-1.3	-1.9	-2.0	-1.3	-1.1	-2.6	-1.3
Alzheimer’s Disease (including proxy)	1.5	2.2	5.1	2.2	1.5	1.9	1.7	1.6	0.2	2.2	1.6	1.0	1.1	0.8	1.0	0.5
Multivitamins +/- minerals	1.5	1.9	4.2	2.0	-0.5	0.0	1.3	0.8	1.8	1.6	1.8	1.8	1.1	1.8	1.0	0.7
Time employed in main current job	1.5	1.7	4.3	1.0	1.3	1.6	2.1	1.2	0.7	0.4	1.6	0.9	1.0	1.6	1.1	1.7
Chronic bronchitis/emphysema (mother)	1.5	1.8	5.5	1.5	1.3	0.7	0.7	0.5	0.8	1.2	1.3	1.7	2.0	2.3	1.2	0.5
Bipolar Disorder or Schizophrenia	1.4	3.3	6.3	0.6	2.3	1.4	2.5	1.8	1.4	2.0	1.0	1.2	1.8	1.7	2.5	2.2
Alzheimer’s Disease (in mother)	1.4	1.6	3.6	1.9	1.1	1.7	1.4	0.9	-0.1	1.5	1.3	1.4	1.3	1.6	0.5	-0.1
Blood Red Count	1.4	13.7	30.4	2.1	3.5	3.6	3.0	4.7	3.1	2.6	1.9	5.5	4.7	4.8	3.9	2.6
Stomach or abdominal pain in last month	1.4	1.7	3.8	-1.9	-0.5	-0.9	-1.3	-1.7	-1.4	-0.9	-1.6	-1.7	-1.9	-1.0	-0.6	-0.5
Pain all over the body in last month	1.4	1.5	4.6	-1.3	-1.0	-1.1	-0.5	-1.5	-2.1	-0.7	-1.5	-1.0	-1.6	-0.4	-0.6	-1.2
Pulse wave Arterial Stiffness index	1.4	1.7	3.3	0.3	1.8	1.5	1.5	1.8	0.8	1.1	0.9	1.2	0.9	1.3	1.6	1.4
Eye problems/disorders: None of the above	1.4	1.6	7.0	0.2	0.2	1.6	0.9	1.1	2.6	1.3	1.2	1.2	0.4	0.8	1.9	-0.0
Commuting to job workplace: Cycle	1.4	1.7	5.6	-1.7	1.2	-0.3	1.9	1.1	2.4	1.1	-1.0	0.5	-0.6	-1.9	0.6	-0.3
Body Mass Index (BMI) (2010)	1.3	1.8	3.2	1.4	1.8	1.3	1.4	1.5	1.7	1.0	1.1	1.4	1.7	1.2	0.9	0.6
Coronary Artery Disease (CAD)	1.3	1.6	6.6	1.1	1.0	2.6	-0.6	2.3	0.9	0.4	2.2	0.3	0.4	0.1	-0.2	0.2
Frequency of depressed mood in last 2 weeks	1.3	1.8	3.5	-0.9	-0.3	-1.1	-1.2	-1.0	-1.9	-0.9	-1.9	-1.4	-1.6	-1.7	-1.6	-1.1
Hand grip strength (right)	1.3	3.5	7.6	1.3	2.6	0.6	0.6	2.6	2.7	2.3	0.8	1.9	1.0	0.7	2.8	1.9
Neuroticism score	1.3	2.6	5.6	-1.1	-0.5	-1.9	-1.5	-1.8	-1.9	-1.1	-2.4	-1.4	-2.0	-1.6	-1.8	-1.4
Hair/balding pattern: Pattern 3	1.3	1.9	6.6	-1.1	-0.9	-1.9	-2.6	-1.0	-1.5	-1.6	-0.1	-1.2	-1.6	-1.3	-0.6	0.4
Hypothyroidism/myxoedema (self-reported)	1.3	2.6	7.3	-2.0	-1.5	-2.4	-2.4	-1.2	-0.3	0.1	-2.7	-0.3	-0.9	-2.2	-0.0	-1.3
Wears glasses or contact lenses	1.3	1.5	4.8	1.4	0.7	1.6	-0.3	0.5	0.9	1.2	0.7	1.2	1.5	0.7	1.6	2.2
Ever depressed for a whole week	1.3	1.6	4.3	-1.3	-0.2	-1.6	0.2	-1.3	-2.1	-1.3	-0.4	-1.6	-1.6	-0.6	-1.6	-0.9
Arm predicted mass (left)	1.3	6.4	14.8	2.6	2.4	1.5	1.6	3.3	1.9	2.2	1.2	3.0	3.9	2.7	3.1	2.0
Neuroticism (Nagel 2018)	1.2	2.9	7.7	-2.1	0.1	-1.8	-0.8	-1.5	-1.8	-1.7	-2.8	-1.9	-1.7	-1.6	-2.1	-0.6
Ulcerative Colitis (UC)	1.2	2.3	8.8	-3.0	-0.8	-1.4	-1.5	-1.9	-1.1	-1.4	-1.7	-1.2	-1.5	-1.3	-1.2	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	7.0	1.8	1.5	2.2	0.8	2.6	2.6	2.1	1.9	1.6	2.0	1.1	2.3	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	5.1	-0.6	-1.0	-0.3	0.2	-1.4	-0.7	-0.8	-0.7	-2.2	-1.1	-1.0	-2.3	-1.5
Chest pain or discomfort	1.2	1.8	6.5	-1.7	-0.7	-1.0	-0.5	-2.6	-1.3	-1.4	-0.3	-1.7	-1.2	-1.3	-1.3	-0.8
Medication for cholesterol	1.2	1.8	4.1	1.8	0.6	2.0	0.9	2.0	0.7	1.0	0.3	1.1	1.9	1.4	1.1	1.3
Medication: Blood pressure	1.2	2.3	5.1	-1.4	-1.0	-1.7	-1.3	-2.3	-1.5	-1.8	-0.9	-1.4	-1.6	-1.1	-1.8	-1.3
High cholesterol (Self-reported)	1.2	2.2	4.1	-1.8	-0.6	-1.5	-0.2	-1.6	-2.0	-1.3	-1.4	-1.6	-1.7	-1.1	-2.0	-1.2
Schizophrenia (2018)	1.1	2.3	7.3	0.4	1.8	1.1	2.7	1.7	1.5	1.3	0.6	0.7	1.5	1.4	1.5	1.8
Neuroticism (2016)	1.1	1.6	4.2	-1.5	-0.8	-0.8	0.1	-1.4	-1.3	-1.1	-0.6	-1.8	-2.1	-1.0	-1.6	-0.9
Hand grip strength (left)	1.1	2.9	6.6	1.6	2.1	0.4	0.4	2.4	2.2	2.4	0.8	1.2	0.6	0.2	2.6	2.2
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	3.9	-0.4	0.8	1.0	-0.3	1.3	1.9	0.1	1.7	2.0	1.9	1.3	1.6	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	3.8	-1.3	-0.8	-1.2	-0.8	-1.4	-1.8	-1.9	-1.1	-0.3	0.3	0.6	-1.0	-0.7
Age at first live birth	1.1	1.9	5.2	0.8	1.1	0.5	1.0	1.1	1.7	2.3	1.7	1.2	1.3	0.6	1.9	1.6
Medication: Blood pressure	1.1	1.9	4.8	0.4	-1.4	-1.3	-0.1	-1.5	-1.8	0.0	-1.8	-1.4	-2.2	-1.6	-1.0	-1.6
Reaction Time	1.0	1.9	4.7	-1.7	-0.7	-0.1	-0.7	-1.5	-0.6	-1.9	0.4	-1.9	-1.0	-0.6	-2.2	-2.0
Medication: Cholesterol lowering	1.0	1.6	4.1	0.2	-0.7	-1.0	0.2	-1.0	-2.0	0.0	-1.2	-1.6	-1.4	-1.1	-1.6	-2.0
Medication: Lansoprazole	1.0	1.2	3.5	-0.9	0.1	-0.1	0.5	0.5	-1.1	-1.2	-0.5	-1.9	-1.7	-1.0	-1.9	0.2
Peak expiratory flow (PEF)	1.0	2.4	6.6	1.2	0.1	0.1	0.7	2.1	2.3	2.6	-1.1	1.4	1.1	0.0	2.2	1.9
Pulse wave peak to peak time	1.0	1.2	2.6	-0.2	-1.6	-1.3	-1.4	-1.6	-0.6	-1.0	-0.6	-1.0	-0.6	-1.0	-1.3	-1.0
Arm predicted mass (right)	1.0	5.0	10.6	1.9	2.4	1.2	1.1	3.1	1.8	2.0	0.8	2.7	3.2	2.2	3.1	1.7
Family relationship satisfaction	1.0	1.2	4.4	0.7	2.1	1.1	-0.4	1.1	0.3	1.4	0.3	1.1	0.4	0.2	1.6	1.5
Illnesses of siblings: Diabetes	1.0	1.2	2.6	-0.9	-0.4	-0.5	-1.3	-1.0	-1.4	-1.2	-1.0	-1.6	-1.4	-1.1	-1.4	-0.5
Arm fat-free mass (left)	1.0	5.0	12.2	2.2	2.1	1.4	1.3	3.0	1.7	1.9	0.9	2.7	3.5	2.3	2.8	1.6
Risk taking	1.0	1.4	3.9	-2.0	0.3	-1.7	-0.6	0.1	-1.0	-1.7	-1.0	-0.8	-1.2	-1.1	-1.5	-0.9
Heart disease (siblings)	1.0	1.2	4.8	-0.0	-0.9	-0.4	0.4	-0.7	-2.2	0.0	-2.2	-0.9	-0.8	-0.8	-1.1	-1.0
LDL Cholesterol	0.9	1.4	7.4	0.8	0.8	1.0	2.7	1.1	1.6	0.3	-0.3	0.4	1.3	1.9	0.2	0.0
Sitting height	0.9	6.5	16.6	1.6	1.8	1.9	1.6	3.1	2.2	2.6	2.0	2.2	3.3	2.1	4.1	3.3
Forced vital capacity (FVC)	0.9	3.3	6.0	2.3	1.7	1.5	1.1	1.9	2.4	2.3	1.9	1.6	2.1	1.0	2.0	1.3
Diabetes (self-reported)	0.9	1.3	4.4	-0.7	-1.6	-1.0	-0.8	-1.3	-1.5	-1.2	-2.1	-0.5	-0.8	-0.3	-1.2	-0.4
Trunk fat-free mass	0.9	5.4	10.6	2.3	2.1	1.2	1.2	3.2	2.0	2.5	1.5	2.6	3.3	2.1	3.3	1.5
Happiness	0.9	1.1	2.3	1.0	0.8	1.1	-0.1	0.7	0.3	0.6	1.5	1.1	1.3	1.2	1.2	1.5
Trunk predicted mass	0.9	5.3	10.6	2.3	2.1	1.2	1.1	3.2	2.1	2.5	1.5	2.6	3.3	2.0	3.2	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	4.1	-2.0	0.1	-0.5	-1.5	-1.2	-0.4	-0.0	-1.4	-1.2	-0.9	-1.7	-0.3	-0.6
Ever had bowel cancer screening	0.9	1.0	2.0	1.2	-0.1	0.6	1.1	1.0	0.3	0.8	1.0	1.3	1.1	1.4	1.1	1.2
Medication: Gliclazide	0.9	1.0	4.4	-1.3	-0.2	-0.9	-2.1	-0.6	-1.6	-1.4	0.1	0.6	-0.1	1.1	0.3	-0.2
Average weekly spirits intake	0.8	1.0	3.4	-1.6	-0.1	0.7	-0.3	1.4	1.9	-0.3	-1.0	0.1	0.5	-0.8	0.5	1.4
Number of incorrect matches in round	0.8	1.2	3.5	-1.5	-0.5	-1.6	1.3	-0.5	-1.5	-0.9	-1.9	-0.4	-0.4	-0.4	-0.7	-1.3
Alcohol usually taken with meals	0.8	1.4	5.5	-0.1	-2.4	-1.1	-0.5	-1.7	-0.6	-0.2	-0.8	-1.0	-0.6	-0.5	-1.1	-2.0
Fluid intelligence score	0.8	1.7	4.5	0.6	0.7	0.9	0.0	0.8	1.5	0.7	1.6	1.8	1.6	1.7	2.1	1.3
Standing height	0.8	8.0	19.2	2.1	1.9	1.9	2.5	2.9	2.9	3.2	2.5	3.1	2.8	2.7	4.4	2.9
Breastfed as a baby	0.8	1.0	2.9	-0.3	-1.7	-1.0	0.2	-1.4	-1.3	-1.4	-0.3	-0.8	-0.6	-0.1	-1.4	-1.1
Arm fat-free mass (right)	0.8	4.1	9.1	1.7	2.1	0.9	0.7	3.0	1.6	1.9	0.8	2.5	3.0	1.9	2.9	1.5
Suffer from ‘nerves’	0.8	1.2	4.7	-0.9	-0.8	-1.6	-0.9	-1.3	-2.2	-0.4	-1.3	-0.6	-1.0	-0.8	-0.5	-0.7
Mineral and other dietary supplements	0.8	1.1	3.3	-1.0	0.2	-0.7	-0.2	-0.4	-1.8	-1.1	-0.9	-1.1	-1.8	-0.9	-0.7	-1.2
Medication: Aspirin	0.8	1.0	3.0	1.7	0.3	1.3	0.5	0.5	0.3	1.7	1.3	0.9	0.8	0.2	0.9	0.8
Alcohol drinker status: Previous	0.8	0.9	3.5	1.9	-0.0	0.2	0.7	-0.3	0.6	1.2	-0.9	0.6	1.3	1.3	0.8	0.8
Bipolar Disorder (2018)	0.7	1.2	4.1	0.5	1.4	0.8	0.6	0.8	0.5	1.5	0.8	0.9	1.0	0.9	2.0	1.2
Crohns Disease (2012)	0.7	1.2	2.4	1.5	1.2	0.9	1.5	0.4	0.4	0.8	0.8	1.1	1.1	1.5	1.1	0.7
Primary Biliary Cirrhosis	0.7	1.0	5.2	0.4	2.0	0.9	0.3	2.3	0.9	1.2	0.6	-0.2	-0.2	-0.2	0.4	0.4
Respiratory disease	0.7	1.7	3.7	-0.1	-1.1	-1.9	-0.8	-0.9	-1.5	-1.1	-0.8	-1.2	-1.9	-1.1	-1.7	-1.5
Neuroticism	0.7	1.6	7.5	-0.9	0.2	-1.5	-0.5	-1.7	-1.6	-0.9	-2.7	-1.0	-0.5	-1.1	-1.2	-0.4
Severe depression (siblings)	0.7	0.7	2.5	-0.8	-0.2	-1.3	-0.6	-1.6	-0.9	0.2	-0.4	-0.8	-0.7	-0.4	-0.6	-1.4
Chronic bronchitis/emphysema (father)	0.7	0.8	1.4	-1.0	-0.9	-1.0	-0.0	-0.8	-1.2	-1.1	-0.4	-1.2	-1.2	-0.3	-1.0	-0.8
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	4.9	1.8	1.3	1.0	1.0	2.0	2.2	2.0	1.0	1.3	1.7	0.5	2.0	1.7
Glaucoma (self-reported)	0.7	0.8	4.6	0.7	-1.3	-0.9	-0.6	-0.5	-2.1	0.2	-1.2	-0.2	0.4	0.0	0.2	1.0
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.6	-0.2	-1.1	-1.1	-0.8	-1.3	-1.0	-1.6	-0.9	-0.7	0.0	0.2	-1.2	-0.7
Medication for pain relief, constipation, heartburn	0.7	1.1	3.6	-1.9	0.5	-0.8	-1.9	-1.1	-0.3	-1.3	-1.0	-0.3	-0.4	-1.4	-0.7	-0.4
Migraine (self-reported)	0.7	0.8	2.4	1.4	0.8	-0.0	0.0	0.4	1.0	0.9	-0.2	1.0	0.9	1.2	1.5	0.9
Medication: Seretide 50 evohaler	0.7	0.9	3.0	-0.0	0.6	1.1	1.4	1.2	1.7	0.4	0.4	1.0	0.8	0.0	0.8	0.7
Pulse rate, automated reading	0.7	2.3	8.3	0.5	1.9	1.2	2.9	2.4	1.6	1.0	-0.7	-1.8	-1.1	-1.5	-0.3	0.5
Comparative height size at age 10	0.7	3.9	8.4	1.2	1.5	1.5	2.3	2.3	2.2	2.7	1.3	2.1	1.4	1.0	2.9	2.2
Leg pain on walking	0.7	0.8	2.9	-0.3	-0.5	-0.6	-1.2	-1.7	-1.2	-0.9	-0.9	-0.3	-0.2	1.3	-0.8	-0.4
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.8	0.8	0.7	0.0	0.7	0.8	1.1	0.5	0.2	1.4	1.0	1.7	1.0	0.1
Supplements: Vitamin C	0.7	0.8	4.2	2.0	1.0	-0.1	-0.1	0.7	1.5	0.8	1.1	-0.1	0.2	0.7	-0.3	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	5.2	-0.4	0.6	0.2	-0.5	-0.5	1.5	0.9	0.4	1.2	1.8	1.1	2.3	2.0
Whole body fat-free mass	0.7	4.2	10.5	1.8	1.8	0.8	1.2	2.8	1.7	1.9	1.0	2.4	3.2	2.0	2.8	1.4
Commuting to job workplace: Walk	0.7	0.7	2.0	0.4	0.4	1.1	1.0	0.7	0.8	0.8	-0.3	1.3	1.4	0.6	0.7	0.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	4.5	-1.0	-1.2	-2.1	-1.6	0.2	0.1	-0.1	-1.1	0.6	-0.7	-1.1	0.8	-0.5
Whole body water mass	0.7	4.2	10.8	1.8	1.8	0.8	1.1	2.8	1.6	1.9	1.0	2.5	3.3	2.0	2.8	1.4
Number of self-reported non-cancer illnesses	0.7	1.3	4.0	0.3	-1.6	-1.4	0.4	-2.0	-1.7	0.1	-1.6	0.4	-0.8	0.6	0.0	-1.0
Ever taken oral contraceptive pill	0.7	0.8	2.4	0.2	-0.6	-1.3	-1.3	-0.5	0.2	-0.4	0.7	-0.9	-1.5	-0.4	-1.0	-1.0
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.8	0.3	0.9	0.3	0.5	0.8	1.0	0.3	-0.3	1.2	1.5	0.6	0.9	1.7
Alcohol drinker status: Never	0.7	0.9	3.4	-0.7	-0.3	-0.2	-0.4	-0.1	-1.8	-0.8	-0.8	-1.1	-1.3	-0.3	-1.5	-0.6
Basal metabolic rate	0.7	3.7	9.5	1.7	1.6	0.6	1.4	2.7	1.4	1.6	0.7	2.4	3.1	2.1	2.5	1.5
Myopia	0.7	1.0	4.9	-1.1	-1.2	-1.3	-0.7	-0.6	-2.2	-0.6	-0.7	-0.7	-0.3	-0.8	-0.4	-0.4
Alzheimer’s Disease (in father)	0.6	0.6	1.9	0.9	0.3	0.7	0.6	1.4	0.0	1.2	0.6	-0.6	-0.5	-1.4	0.3	0.1
Irritable Bowel Disease (IBD)	0.6	1.4	5.0	-2.2	-0.4	-0.6	-0.3	-1.9	-0.6	-0.9	-1.4	-1.1	-1.5	-1.4	-0.8	-0.6
Prostate Cancer	0.6	0.8	3.1	-0.9	-1.8	-0.5	-0.5	-0.5	-1.3	-0.9	-1.0	-0.4	-0.0	0.4	-1.0	-1.0
Height	0.6	11.1	29.1	2.5	0.6	2.7	2.1	3.2	2.6	3.5	2.5	4.3	3.3	3.6	5.4	4.2
Type 2 Diabetes (T2D) (2018)	0.6	1.2	5.0	-1.1	-0.6	-1.2	-0.7	-1.7	-0.9	-0.7	-2.2	-0.3	-1.1	-0.2	-0.7	-0.7
Sensitivity / hurt feelings	0.6	1.0	3.5	-0.4	0.4	-0.9	-1.2	-0.8	-0.8	-1.0	-0.5	-1.2	-1.9	-1.1	-1.2	-0.4
Hearing difficulty/problems: Yes	0.6	0.9	4.0	-0.4	-0.9	-0.7	-0.3	-2.0	-1.2	-0.1	-2.0	0.1	0.5	0.3	-0.2	-0.8
Vitamin and mineral supplements	0.6	0.8	2.5	-1.3	0.8	0.7	-0.1	-0.3	-1.5	-0.1	-1.1	-0.7	-0.9	-1.6	0.1	-0.7
Relative age voice broke	0.6	0.9	3.7	1.8	0.9	0.4	1.9	0.4	0.3	0.7	0.5	0.8	0.7	1.5	0.4	-0.1
Medication: Levothyroxine sodium	0.6	0.9	3.2	-1.1	-1.0	-1.3	-1.0	-0.5	-0.1	-0.5	-1.8	-0.8	-0.1	-1.2	-0.7	-1.0
Nervous feelings	0.6	1.1	2.0	-1.1	0.1	-1.2	-0.8	-1.2	-1.2	-0.3	-1.2	-1.4	-1.1	-1.3	-1.0	-0.5
Mouth/teeth dental problems	0.6	0.9	2.6	-0.9	-0.7	0.3	1.0	-1.0	-0.3	-1.3	-0.1	-1.4	-0.6	-0.9	-1.6	-1.2
Falls in the last year	0.6	0.8	3.2	-1.8	0.1	-1.0	-0.6	0.2	0.9	0.0	-0.9	-1.0	-1.0	-1.2	-0.1	-0.1
Qualifications: A levels/AS levels or equivalent	0.6	1.4	7.6	-0.4	-1.4	-0.4	-2.8	-1.4	-1.4	-0.7	1.1	-1.3	-0.6	-0.4	-0.3	-0.3
Tense / ‘highly strung’	0.6	1.0	3.2	0.8	1.8	0.8	1.8	0.8	0.1	0.1	0.8	0.7	0.6	1.5	0.1	0.6
Pulse wave reflection index	0.6	0.8	3.4	-0.4	1.8	0.0	-1.1	-0.1	-0.9	0.9	0.9	0.4	0.5	-0.1	1.4	0.6
Ever highly irritable/argumentative for 2 days	0.6	0.7	3.8	-0.6	-0.1	-0.7	-1.1	-0.5	-1.9	-0.2	-0.6	-1.0	-0.3	-0.9	-0.9	0.4
Loud music exposure frequency	0.6	0.7	2.4	-0.8	-0.3	-0.5	-1.5	-0.8	-1.6	-0.6	-1.3	0.0	-0.0	-0.3	-0.1	-0.4
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	5.2	0.0	0.2	0.3	-1.8	-0.7	0.1	0.5	2.3	0.9	0.4	0.6	1.2	0.1
Blood clot in the leg (DVT)	0.6	0.7	2.5	1.6	-1.6	-0.3	0.4	-0.2	-0.9	0.7	-0.1	0.7	1.4	0.7	0.0	0.2
Headache pain in last month	0.6	0.9	4.0	1.8	0.3	-0.6	-0.5	0.1	0.2	0.5	1.0	0.8	0.2	2.0	1.1	1.0
Number of full brothers	0.6	0.7	2.0	0.0	1.4	-0.0	0.9	0.6	0.6	-0.3	-1.0	0.8	1.4	1.2	0.3	0.8
Guilty feelings	0.6	1.0	3.1	-1.0	-0.5	-0.7	-1.0	-0.2	-0.3	-0.2	-1.3	-1.2	-1.8	-1.4	-1.0	-0.4
Eye problems/disorders: Glaucoma	0.6	0.7	3.1	0.4	-1.3	-0.9	-0.5	-0.2	-1.8	0.2	-1.5	-0.4	0.2	-0.3	-0.2	0.6
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	3.0	1.7	-1.5	-0.4	0.4	-0.3	-0.7	0.9	-0.2	0.7	1.5	0.8	0.1	0.1
Major Depression (MDD)	0.5	0.6	5.0	0.2	-0.3	-0.1	0.5	-0.6	0.2	1.0	-2.2	0.2	-0.2	-0.2	0.0	-1.0
Heel T-Score	0.5	4.2	6.3	1.3	2.4	2.5	1.2	2.0	2.5	1.1	1.9	2.5	2.1	2.2	2.3	1.9
Number of treatments/medications taken	0.5	0.8	2.3	0.2	-1.2	-1.4	0.5	-1.2	-0.6	0.0	-1.5	-0.6	-1.1	-0.3	-0.5	-0.8
Medication for hormone replacement therapy	0.5	0.6	1.8	-0.9	1.3	-0.4	-0.0	-0.3	1.2	0.1	1.0	-0.3	-1.1	-1.0	0.1	-0.5
Medication: Co-codamol	0.5	0.6	4.1	-2.0	-0.6	-0.5	0.5	-0.5	-0.2	-0.7	-0.9	-0.5	-0.3	-0.0	-0.0	0.8
Leg fat-free mass (left)	0.5	2.4	8.3	1.1	1.2	0.1	1.0	2.0	0.9	1.3	0.4	1.9	2.9	1.7	2.2	1.2
Current tobacco smoking	0.5	0.8	3.2	-0.6	1.8	0.2	-0.0	0.2	-0.9	-0.9	0.3	-1.4	-0.5	-0.6	-1.4	-0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	4.0	0.6	2.0	0.0	0.8	0.5	0.8	-0.5	0.7	0.3	0.5	0.5	-0.4	-0.2
Serious illness, injury or assault to yourself	0.5	0.6	2.0	0.0	-0.7	0.6	0.7	0.1	1.4	0.6	-0.1	0.4	1.2	0.1	0.8	1.1
Supplements: Glucosamine	0.5	0.6	2.3	1.5	-0.2	0.2	-0.1	-0.0	1.5	1.1	0.4	0.5	1.0	0.9	-0.3	-0.4
Leg predicted mass (left)	0.5	2.5	8.5	1.1	1.3	0.2	1.0	2.0	1.0	1.3	0.4	1.9	2.9	1.8	2.2	1.3
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.8	-0.0	-1.0	-1.3	0.8	-0.0	-0.3	0.3	-0.9	1.2	1.1	0.9	0.9	0.4
Medication: Ramipril	0.5	0.6	2.0	-0.2	-0.8	-0.3	-0.3	-1.0	-1.4	-1.1	-0.2	-1.1	-0.2	0.0	-1.1	0.4
Prospective memory result	0.5	0.7	3.5	-0.3	1.9	0.4	1.5	0.7	-0.4	-0.1	-0.1	-0.3	-0.0	-0.5	0.1	1.4
Exposure to tobacco smoke at home	0.5	0.5	2.3	0.9	-0.1	0.6	-0.2	1.1	1.5	0.6	0.9	0.8	-0.4	0.3	0.1	0.0
Gout (self-reported)	0.5	0.7	2.9	1.2	0.2	0.1	-0.0	1.1	0.9	1.7	1.2	-0.2	-0.6	0.3	-0.0	-0.7
Medication: Amlodipine	0.5	0.8	4.6	-0.8	-0.2	-0.3	0.8	-0.3	-1.3	-2.1	-0.3	-0.7	-0.3	-0.1	-1.1	-0.4
Medication: Ibuprofen	0.5	0.5	2.2	0.7	-0.3	0.3	1.5	0.2	-0.5	0.8	0.5	0.3	-0.1	0.6	1.0	1.3
Medication: Omeprazole	0.5	0.6	3.2	-0.7	-0.6	-0.9	1.2	-0.2	0.1	0.1	-1.8	-0.5	-0.4	0.1	-0.2	-0.8
Alcohol intake frequency.	0.5	1.2	2.9	-0.5	-1.1	-0.5	-0.2	-1.3	-1.7	-1.2	-1.7	-1.3	-0.9	-0.3	-1.6	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	3.7	-0.9	-0.1	-0.2	-1.9	-1.0	-0.4	-1.2	0.2	0.2	0.1	0.1	-0.6	-0.8
Hypertension (Self-reported)	0.5	1.3	3.4	0.2	-1.1	-1.3	0.1	-1.8	-1.5	-0.7	-0.9	-0.9	-1.8	-0.5	-1.0	-1.5
Friendships satisfaction	0.5	0.6	1.8	0.7	0.7	0.6	-0.7	0.6	-0.5	1.3	0.6	1.0	0.5	-0.1	1.2	0.3
Hearing aid user	0.5	0.5	1.6	0.1	-0.6	-0.1	-0.3	-0.1	-1.3	0.7	-0.2	-1.0	-1.1	-0.9	-0.1	-0.9
Diastolic blood pressure, automated reading	0.5	1.4	2.6	1.5	1.2	1.1	1.5	1.0	1.6	1.2	1.2	1.2	0.4	1.5	1.2	0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	3.6	-0.1	-0.3	-0.9	1.9	0.2	0.0	0.7	-1.7	-0.3	-0.1	0.3	-0.1	-0.3
Age at First Birth	0.4	0.6	3.8	0.8	0.4	1.0	-0.3	0.2	0.4	0.7	1.9	0.7	0.4	0.5	0.4	-0.4
Lupus	0.4	0.6	1.5	-0.6	1.1	0.7	1.1	1.2	1.2	-0.3	0.0	0.1	0.2	0.4	-0.2	-1.0
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.5	1.2	-0.8	-0.4	0.7	-0.6	-1.1	0.5	0.6	-0.2	-0.1	0.5	-0.0	0.7
Cardiovascular Disease	0.4	1.3	4.2	-0.4	-0.9	-1.2	0.3	-2.1	-1.7	-1.0	-0.4	-1.1	-1.4	-0.6	-1.3	-0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.0	-1.4	0.1	-0.4	0.3	-0.2	-0.5	-1.1	-0.9	-0.5	-0.3	-0.3	-1.1	0.1
Diabetes (mother)	0.4	0.6	1.6	-0.8	-0.5	-0.6	-0.3	-1.1	-0.5	-0.3	-0.6	-1.0	-0.9	-0.5	-1.3	-0.5
Maternal smoking around birth	0.4	0.5	1.5	-0.6	1.2	0.7	0.7	0.5	-0.2	-1.0	-0.0	-0.1	1.0	1.0	-0.4	0.7
Taking other prescription medications	0.4	0.7	3.7	-0.7	-0.7	-1.1	0.6	-0.3	-0.7	-0.4	-1.9	-0.5	-1.1	0.3	-0.2	-0.6
Weight	0.4	1.9	5.1	1.1	0.5	-0.2	1.4	1.6	0.2	0.5	-0.7	1.9	2.2	2.0	1.6	1.5
Hip circumference	0.4	1.6	5.5	1.3	0.6	0.3	0.8	1.5	0.4	0.4	-0.0	1.6	2.4	2.0	1.1	1.3
Mouth/teeth dental problems: Dentures	0.4	0.6	3.8	0.5	-1.1	-0.6	-0.8	-0.9	-2.0	-0.1	-0.6	-0.2	-0.3	0.3	-0.5	0.6
Illnesses of mother	0.4	0.4	1.8	-0.3	-0.3	0.3	0.6	0.6	0.2	0.1	0.6	1.2	0.4	-0.2	1.3	1.0
Hair/balding pattern: Pattern 4	0.4	0.9	2.9	-0.2	-1.7	-0.7	-0.3	0.1	0.6	-0.5	-1.1	-0.5	-0.7	-1.1	-1.1	-1.6
Exposure to tobacco smoke outside home	0.4	0.6	2.3	-0.0	-0.2	0.7	0.3	0.0	0.2	-0.1	-0.6	1.5	1.0	1.1	0.9	1.1
Health satisfaction	0.4	0.5	1.1	0.2	0.9	1.1	-0.7	-0.5	-0.3	-0.2	1.0	0.8	0.2	0.6	0.5	1.0
Neck or shoulder pain in last month	0.4	0.6	1.7	-0.2	-1.0	-1.0	-0.3	-0.6	-0.1	-1.3	-1.0	-0.6	-0.6	0.3	-1.1	-0.2
Medication: Allopurinol	0.4	0.5	1.6	1.0	0.4	-0.2	-0.9	0.3	-0.5	0.8	1.3	-0.6	-0.9	-0.4	-0.5	-0.7
Leg fat mass (right)	0.4	1.5	3.8	1.3	0.3	-0.3	1.3	1.1	-0.2	0.3	-1.9	1.6	1.8	2.0	1.0	0.8
Medication: Aspirin	0.4	0.6	2.1	1.4	0.1	0.9	0.3	0.2	0.1	1.4	1.0	0.8	0.5	0.0	0.8	0.3
Smoking status: Previous	0.4	0.7	2.2	1.1	-0.6	0.4	0.7	-0.5	0.4	-0.0	0.0	0.8	1.0	1.2	0.8	1.5
Leg fat-free mass (right)	0.4	2.3	7.7	0.9	1.2	0.2	0.9	2.1	1.0	1.0	0.8	1.9	2.8	1.7	1.9	1.3
Average weekly red wine intake	0.4	0.5	2.1	0.5	0.2	0.6	-0.5	-0.5	-0.7	1.4	1.4	0.3	-0.2	0.1	1.1	-0.3
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.2	0.1	-0.9	-0.8	-0.8	-0.6	-1.1	-0.3	-0.8	-0.5	-0.9	-0.2	-0.7	-1.0
Loneliness, isolation	0.4	0.5	1.3	-0.4	0.6	-0.6	-0.2	-0.2	-0.4	0.5	-1.1	-0.7	-1.1	-1.1	-0.4	-1.1
Qualifications: nursing, teaching	0.4	0.7	4.0	-1.0	-0.7	-0.8	-2.0	-0.1	-0.4	-1.0	1.1	-0.1	0.4	0.5	-0.2	-0.2
Smoking status: Current	0.4	0.7	3.5	-0.8	1.9	-0.1	-0.1	0.1	-0.6	-0.9	0.2	-1.2	-0.3	-0.6	-1.2	-0.7
Leg predicted mass (right)	0.4	2.3	7.6	0.9	1.2	0.3	0.9	2.1	1.1	1.1	0.9	1.9	2.8	1.6	2.0	1.3
Medication: Lisinopril	0.4	0.6	2.5	-0.1	0.9	0.6	0.4	0.2	-0.0	0.8	-0.3	-0.8	-1.6	-1.2	0.3	-0.6
Medication: Atorvastatin	0.4	0.5	1.3	0.0	0.8	0.4	0.4	0.2	-0.2	0.6	-0.6	1.1	1.1	0.8	0.4	-1.1
Irritability	0.4	0.7	3.1	0.1	-0.3	-1.8	-0.2	-1.2	-1.5	0.0	-0.8	-0.2	-1.1	-0.5	-0.5	-0.3
Unable to work because of sickness or disability	0.4	0.5	1.6	-0.5	0.8	0.9	-1.2	0.2	-0.2	0.8	-0.1	0.1	0.0	-0.7	0.7	-1.0
Pack years of smoking	0.4	0.6	1.7	0.7	1.1	0.5	1.1	0.2	-0.3	-0.3	-0.1	0.9	1.2	0.9	0.2	1.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.6	0.2	-1.1	0.2	1.0	0.2	-0.1	0.6	1.2	1.4	1.3	1.6	1.2	-0.4
Verbal and Numeric Reasoning (VNR)	0.3	0.8	2.4	0.4	-0.1	0.7	0.1	-0.6	0.9	0.6	0.8	1.3	1.4	1.5	1.3	-0.3
HDL Cholesterol	0.3	0.5	1.6	-1.0	0.2	-0.3	-0.6	0.5	-0.8	-0.0	-1.3	0.3	0.7	-0.9	0.6	-0.1
Rheumatoid Arthritis	0.3	0.5	1.7	-1.3	-0.9	-0.6	-0.3	-0.9	-0.5	-0.3	-0.9	-0.8	0.2	-0.2	0.3	0.6
BMI	0.3	1.7	6.2	0.7	0.9	-0.6	1.0	1.4	0.0	-0.4	-1.2	1.3	2.5	2.3	0.7	1.3
Waist Hip Ratio (WHR)	0.3	1.2	3.5	-1.9	-0.2	-0.3	1.5	0.1	-0.8	-1.4	-1.8	-0.5	-1.2	-0.6	-0.9	-0.7
Smoking Status	0.3	0.7	2.9	-0.6	0.7	-0.3	0.4	-0.9	-0.6	-1.7	-0.3	-1.1	0.0	-0.2	-1.6	-0.0
Allergy or Eczema	0.3	0.8	4.5	-0.4	-0.1	-0.1	1.1	0.5	0.7	-1.0	0.5	0.9	1.1	2.1	0.2	0.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.5	-0.3	-0.5	-0.4	-0.5	-1.2	-0.3	0.3	0.1	0.6	0.1	0.6	1.2	-0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.8	0.1	0.0	-0.2	-0.4	-0.2	-0.9	-0.8	-0.2	-0.2	0.2	0.8	-0.8	0.9
Angina	0.3	0.4	1.7	0.2	-1.3	-0.0	-0.0	0.0	-1.2	0.8	-0.6	-0.4	-0.4	-0.6	-0.5	-0.8
Supplements: Zinc	0.3	0.3	0.9	0.5	0.3	-0.7	0.0	-0.4	0.2	0.1	1.0	0.8	-0.6	0.9	0.8	-0.0
Pack years adult smoking proportion	0.3	0.4	1.0	0.5	1.0	0.3	0.7	0.0	-0.5	-0.5	0.0	0.7	0.9	0.8	0.0	0.9
Trunk fat percentage	0.3	1.0	5.2	-0.3	-0.5	-0.9	1.6	-0.0	-0.7	-1.0	-2.3	0.7	0.4	1.3	-0.1	1.0
Average weekly fortified wine intake	0.3	0.3	1.1	-0.3	-0.2	0.5	0.3	0.7	1.0	0.7	0.1	0.3	1.0	-0.3	0.5	-0.4
High blood pressure	0.3	0.9	2.6	0.2	-0.7	-1.3	0.1	-1.6	-1.1	-0.5	-1.1	-0.5	-1.5	-0.3	-0.5	-1.4
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.0	-0.8	0.3	-0.5	0.9	-0.1	1.3	-0.9	0.7	0.8	0.6	1.4	0.4	0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.3	-1.1	-0.2	-0.7	0.1	-0.2	-0.6	-0.5	-0.8	-0.5	-0.3	-0.2	-0.4	-0.8
Trunk fat mass	0.3	1.3	3.6	0.4	-0.0	-0.6	1.7	0.8	-0.1	-0.2	-1.8	1.4	1.1	1.9	0.9	1.2
Arm fat percentage (right)	0.3	1.1	5.4	0.3	-1.1	-1.1	1.4	-0.2	-1.1	-0.9	-2.3	0.6	0.7	1.4	-0.3	0.3
Father’s age at death	0.3	0.4	3.5	0.0	0.7	0.2	-1.9	-0.5	0.4	-0.0	0.6	0.1	0.2	0.2	0.2	-0.6
Number of live births	0.3	0.4	1.3	0.5	0.5	0.7	-0.1	0.7	1.2	0.6	0.6	0.3	1.0	0.1	0.1	0.7
Noisy workplace	0.3	0.3	1.1	0.1	-0.8	0.3	-0.4	-0.3	-0.6	-1.0	-0.6	0.0	-1.0	0.1	-0.8	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.0	0.1	-0.7	-0.6	1.0	-0.4	-0.9	0.3	0.0	-0.9	-0.7	-0.0	0.1	0.5
Arm fat mass (right)	0.3	1.3	3.5	0.9	0.1	-0.4	1.6	1.0	-0.4	-0.1	-1.4	1.4	1.7	1.9	0.7	0.9
Length of working week for main job	0.3	0.3	1.7	0.7	-0.2	0.6	0.1	0.5	0.4	-0.2	1.0	0.1	-0.1	1.3	-0.5	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.5	-0.6	0.2	-0.5	-0.2	-1.1	-0.9	-0.0	-0.5	-0.5	-0.8	-1.2	-0.3	-0.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	3.3	0.1	0.5	-0.8	-1.8	-0.1	-0.7	0.0	-0.6	0.2	0.4	-0.1	0.4	0.4
Body fat percentage	0.3	1.0	5.9	0.1	-0.5	-0.7	1.5	0.3	-0.6	-0.7	-2.4	1.0	0.5	1.4	0.1	0.9
Leg fat percentage (right)	0.3	1.1	5.4	1.2	0.0	-0.3	1.3	0.7	-0.4	0.2	-2.3	1.3	1.1	1.5	0.4	0.6
Emphysema/chronic bronchitis	0.3	0.4	1.5	-0.2	1.2	0.5	-0.4	-0.0	-0.1	-0.0	1.2	0.6	-0.0	0.0	1.1	0.3
Angina (self-reported)	0.3	0.4	1.6	0.3	-1.3	0.2	0.0	0.3	-0.9	1.2	-0.7	-0.3	-0.3	-0.8	-0.3	-0.7
Mean time to correctly identify matches	0.3	0.6	1.5	-0.5	-0.3	0.9	-0.5	-0.9	0.1	-0.8	0.8	-0.9	-0.7	-0.6	-1.2	-1.1
Heart disease (mother)	0.3	0.4	1.0	0.5	-0.2	0.9	-0.3	-0.7	-0.8	-0.1	0.5	-0.5	-0.5	0.1	-0.9	-1.0
Whole body fat mass	0.3	1.3	3.2	0.6	0.1	-0.4	1.4	1.1	-0.2	-0.1	-1.7	1.5	1.4	1.8	0.9	1.2
Had major operations	0.3	0.3	0.9	1.0	0.5	0.1	0.0	-0.3	-0.6	0.9	0.3	0.2	0.8	0.8	0.1	0.3
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.2	1.1	0.3	-0.5	-0.9	-0.0	-0.9	-0.3	0.1	-0.2	0.8	0.6	-0.3	0.1
Illnesses of father: Heart disease	0.3	0.4	1.0	0.9	-0.4	0.0	0.8	-0.1	-0.5	0.6	0.6	0.6	0.6	1.0	0.1	-0.9
Arm fat percentage (left)	0.3	1.1	6.0	-0.1	-1.1	-1.3	1.0	-0.3	-1.2	-1.1	-2.5	0.3	0.4	1.1	-0.5	0.1
Long-standing illness, disability or infirmity	0.3	0.4	2.0	-0.7	-0.9	-0.3	-0.7	-1.4	-0.8	-0.8	-0.3	0.0	-0.2	0.1	-0.4	-0.2
Diabetes diagnosed by doctor	0.3	0.5	1.5	-0.2	-1.1	-0.3	-0.5	-0.9	-1.1	-0.8	-1.2	-0.0	-0.3	0.3	-0.5	0.1
Osteoporosis (self-reported)	0.3	0.3	2.0	-0.5	0.4	0.6	0.4	0.3	-0.1	-0.6	0.0	-0.3	-1.4	-0.5	-0.3	-0.6
Osteoarthritis (self-reported)	0.3	0.4	1.4	0.4	0.4	1.1	1.2	0.4	0.6	0.2	0.5	1.0	0.2	0.6	0.6	0.2
Financial situation satisfaction	0.3	0.4	1.1	-0.6	0.3	0.6	-0.4	-0.0	-0.9	-0.5	-0.4	-1.0	0.1	-0.3	-0.9	1.0
Commuting to job workplace: Public transport	0.3	0.4	1.5	0.5	0.4	0.3	0.4	0.9	-0.3	1.2	0.3	0.3	-0.1	0.7	0.9	-0.4
Leg fat percentage (left)	0.3	0.9	4.1	1.0	-0.1	-0.4	1.0	0.6	-0.5	-0.3	-2.0	1.2	0.9	1.5	0.0	0.5
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	-0.0	0.0	-0.1	0.7	-0.2	-0.8	-0.2	-0.2	-0.5	-0.8	-0.5	-0.9	-1.1
Cholesterol lowering medication	0.3	0.5	1.8	-1.3	-0.2	-0.5	-0.4	-0.6	-0.8	-0.6	-1.1	-0.0	-0.5	-1.1	-0.6	0.2
Leg fat mass (left)	0.3	1.3	3.4	1.1	0.3	-0.3	1.1	1.1	-0.4	-0.0	-1.7	1.5	1.6	1.9	0.7	0.8
Worry (Nagel 2018)	0.2	0.5	1.5	-1.1	0.6	-0.7	-0.2	-0.5	-0.7	-1.2	-0.9	0.4	0.5	0.6	-0.3	0.5
Crohns Disease (2017)	0.2	0.4	1.4	-0.1	0.9	1.0	1.2	-0.6	0.8	0.3	-0.0	0.1	-0.0	-0.3	0.4	0.0
Breast Cancer	0.2	0.6	1.2	0.8	-0.9	-0.1	0.6	0.9	0.7	1.1	-0.5	0.8	0.6	0.8	0.7	0.8
Triglycerides	0.2	0.3	0.8	0.4	0.9	0.6	0.6	-0.3	0.8	0.5	0.6	-0.2	-0.2	0.5	-0.2	-0.7
Blood Eosinophil Count	0.2	1.5	3.6	-0.9	-1.0	-1.1	-1.9	-1.1	-0.9	-1.8	-1.7	-1.6	-0.7	-0.6	-1.3	0.1
Blood Platelet Count	0.2	1.8	7.9	-1.5	0.2	-0.1	0.1	-0.4	0.4	-2.8	-0.5	-1.7	-1.8	-1.1	-2.0	-0.9
Systolic Blood Pressure	0.2	0.9	3.8	-0.0	-0.4	0.2	-1.2	-1.9	0.2	-0.3	1.3	-1.0	-1.1	-0.3	-0.8	-1.2
Lung FVC	0.2	1.0	2.9	1.7	-0.4	0.9	-0.3	1.7	0.8	0.8	1.6	-0.6	0.3	-0.6	-0.9	0.6
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	0.4	-0.2	0.7	0.8	-0.0	0.1	0.5	0.2	-0.2	0.6	0.3	0.3	0.3
Systolic blood pressure, automated reading	0.2	0.7	2.2	0.9	0.7	1.3	0.5	0.0	0.7	0.2	1.5	0.5	0.4	1.4	-0.1	-0.7
Medication: Metformin	0.2	0.3	1.5	-0.3	0.1	-0.4	-0.3	-0.4	-1.2	-0.2	-1.0	0.3	0.0	0.7	0.2	0.2
Townsend deprivation index at recruitment	0.2	0.3	1.1	-0.7	0.2	-0.1	1.0	-0.8	-1.1	-0.5	0.6	0.5	-0.3	-0.2	0.3	-0.3
Age when periods started (menarche)	0.2	0.5	2.7	-0.2	0.4	0.2	0.4	-0.8	-0.4	0.2	-0.0	-1.0	-1.1	-1.6	0.1	0.7
Qualifications: CSEs or equivalent	0.2	0.3	0.9	0.6	0.2	-0.1	0.7	0.0	-0.6	-0.4	0.5	-0.3	-0.4	0.5	-0.7	1.0
Body mass index (BMI)	0.2	0.7	3.5	0.3	-0.2	-1.0	0.3	0.5	-1.1	-0.8	-1.9	0.6	1.2	0.9	-0.3	0.3
Waist circumference	0.2	0.7	2.3	0.1	-0.0	-0.4	1.0	0.6	-0.9	-0.6	-1.5	1.1	0.9	1.2	0.1	-0.0
Past tobacco smoking	0.2	0.4	1.3	-0.4	0.3	0.3	-0.8	0.7	-0.4	0.5	0.5	-0.4	-0.7	-1.2	-0.5	-1.0
Hearing difficulty/problems with background noise	0.2	0.4	1.4	-0.9	-0.0	-0.4	-1.2	-1.1	-0.6	-0.6	-0.6	0.2	0.0	0.4	0.0	0.4
Had menopause	0.2	0.3	1.0	0.7	0.4	0.7	0.2	1.0	-0.3	0.5	-0.8	0.5	0.4	0.5	0.2	-0.2
Qualifications: None of the above	0.2	0.4	1.8	-0.5	-0.3	0.3	-0.2	0.5	-0.2	-0.4	-1.3	-0.8	-0.8	-1.0	-0.9	0.2
Allergy	0.2	0.6	2.3	0.0	0.4	0.8	-1.3	0.3	-0.5	0.6	-0.9	-0.9	-0.2	-1.5	-0.2	-0.4
Impedance of arm (right)	0.2	0.8	2.9	-0.5	-1.3	-0.2	1.7	-1.5	-0.1	0.1	-0.3	-0.8	-1.4	-0.0	-0.4	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.9	0.4	0.0	0.5	-0.7	-0.4	0.0	0.1	1.0	-0.1	0.3	-0.5	-0.1	0.5
Impedance of arm (left)	0.2	1.0	3.5	-1.2	-1.2	-0.4	0.9	-1.6	-0.3	-0.3	-0.3	-1.2	-1.9	-0.6	-0.9	-0.1
Medication: Paracetamol	0.2	0.4	0.8	0.8	0.0	0.8	0.8	0.6	0.3	0.5	0.7	-0.5	0.5	0.9	-0.1	-0.2
Worry too long after embarrassment	0.2	0.4	0.8	-0.6	0.3	-0.5	-0.9	-0.7	-0.4	-0.6	-0.2	-0.6	-0.7	-0.6	-0.7	-0.8
Wheeze or whistling in the chest in last year	0.2	0.4	1.1	0.1	-0.7	0.0	1.0	-0.4	0.2	0.3	-0.7	1.0	0.1	0.8	0.4	-0.9
Overall health rating	0.2	0.5	1.8	-0.5	-0.9	-0.0	-0.7	-1.2	-1.3	-0.1	-0.8	-0.4	-0.8	-0.9	-0.0	-0.1
Age at last live birth	0.2	0.3	1.2	-0.6	0.2	-0.2	-0.2	-0.7	0.7	0.8	0.2	-0.1	0.0	-1.1	0.2	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.9	-0.4	0.1	-0.7	-0.2	-0.3	1.4	-0.5	0.1	-0.1	-0.3	0.1	-0.1	0.6
Eye problems/disorders: Cataract	0.2	0.3	0.8	0.0	0.8	-0.5	0.4	-0.5	-0.6	-0.6	-0.9	-0.1	0.2	-0.1	-0.8	0.1
Back pain experienced in last month	0.2	0.3	0.9	-0.5	-0.5	0.2	-0.6	0.2	0.2	0.9	-0.9	-0.0	0.7	-0.4	0.4	0.4
Arm fat mass (left)	0.2	0.9	2.6	0.6	0.1	-0.5	1.1	0.9	-0.3	-0.4	-1.6	1.1	1.6	1.6	0.4	0.6
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.6	0.2	-0.7	-0.1	-0.8	-0.3	0.8	0.7	0.3	-0.3	0.4	-0.8	-0.3	-0.0
Medication: Paracetamol	0.2	0.2	0.7	0.8	-0.4	0.5	0.8	0.2	-0.3	-0.0	0.6	-0.4	0.3	0.8	-0.5	-0.0
Ever smoked	0.2	0.3	1.7	0.6	0.3	-0.1	1.3	-0.1	-0.0	-0.2	0.0	0.1	0.5	0.8	0.5	0.8
Number of operations (self-reported)	0.2	0.4	1.5	0.4	-0.1	-0.0	0.9	-0.4	0.1	-0.1	-0.7	0.5	0.3	0.8	-0.7	-1.2
Average weekly beer plus cider intake	0.2	0.3	1.4	-0.8	0.5	0.6	-0.3	-0.5	-0.1	-1.2	0.7	-0.1	0.3	0.4	-0.4	0.8
Fractured/broken bones in last 5 years	0.2	0.3	1.5	1.2	0.7	0.8	-0.2	0.2	-0.2	0.4	0.6	-0.3	-0.1	-0.0	-0.3	0.2
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.0	-0.4	0.6	0.8	-0.2	1.4	1.1	0.2	0.7	0.3	1.1	0.2	0.4	1.0
Pain experienced in last month	0.2	0.4	1.5	-0.3	-0.7	0.4	0.5	0.3	-0.8	-0.6	1.1	0.1	1.2	0.2	-0.7	-0.4
Supplements: Calcium	0.2	0.3	1.2	0.1	-0.5	0.4	-0.7	-0.0	-0.7	-1.1	0.6	-0.2	-0.2	0.2	-0.5	-0.2
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.6	-0.8	0.3	0.4	-0.6	-0.7	-0.4	-0.7	0.1	-0.3	0.2	-0.3	-0.4	0.3
Ovarian Cancer	0.1	0.2	0.4	0.4	-0.6	0.0	0.1	-0.5	-0.5	-0.4	0.1	-0.0	0.4	0.3	-0.3	0.6
Bipolar Disorder (2011)	0.1	0.1	0.6	0.2	-0.0	0.3	0.7	0.6	0.2	0.6	-0.3	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.1	0.5	1.8	-0.6	0.7	1.4	0.6	0.2	0.4	-0.3	-0.3	-0.8	-0.9	-1.2	-0.3	0.4
Lung FEV1/FVC ratio	0.1	0.4	1.0	-0.6	0.4	-0.2	-0.2	0.8	0.5	-0.7	-0.5	0.4	0.9	-0.2	1.0	1.0
Chronotype (morning person)	0.1	0.2	0.6	0.7	-0.2	0.4	0.5	0.3	0.8	0.7	0.3	-0.3	-0.3	-0.1	-0.0	0.1
Impedance of leg (right)	0.1	0.6	1.8	0.6	0.5	1.1	1.3	-0.1	0.8	1.0	-0.2	0.3	-1.1	0.1	0.8	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.9	0.2	0.2	0.2	0.0	0.2	-0.0	0.6	0.9	0.6	-0.3	-0.0	0.5	0.2
Impedance of leg (left)	0.1	0.6	2.0	0.3	0.5	1.3	1.2	-0.1	0.9	0.5	0.3	0.3	-1.4	0.1	0.4	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.7	-0.7	-0.0	0.4	-0.8	0.3	-0.1	0.1	0.6	0.3	-0.3	-0.3	-0.1	-0.0
Heart attack	0.1	0.2	0.5	-0.4	0.7	0.7	-0.3	-0.4	-0.2	-0.3	0.3	-0.0	0.6	0.1	-0.0	0.7
Alcohol intake versus 10 years previously	0.1	0.2	0.4	-0.2	0.6	0.6	-0.0	0.1	-0.5	-0.7	0.0	-0.5	-0.7	0.3	-0.1	0.1
Worrier / anxious feelings	0.1	0.3	0.9	-0.2	1.0	0.4	-0.1	-0.7	-0.6	-0.7	0.2	0.6	0.2	0.6	0.1	0.4
Asthma	0.1	0.2	0.5	0.5	-0.7	-0.6	0.6	-0.2	0.2	0.2	0.6	-0.1	-0.7	-0.3	-0.4	-0.4
Comparative body size at age 10	0.1	0.3	1.3	-0.0	0.0	0.8	-0.7	0.4	0.1	-0.4	0.1	0.2	0.2	0.1	-0.9	-1.1
Qualifications: College or University degree	0.1	0.2	1.3	0.4	0.1	-0.4	0.1	-0.5	0.1	0.2	1.1	-0.1	0.2	-0.5	0.8	0.4
Knee pain experienced in last month	0.1	0.2	1.4	0.2	-0.4	-0.3	0.6	-0.2	0.3	-0.0	-1.2	-0.4	-0.7	0.3	-0.3	0.3
Breast cancer (self-reported)	0.1	0.2	0.6	0.6	-0.3	-0.4	-0.1	-0.3	-0.2	-0.2	0.6	0.0	0.5	0.6	0.0	0.7
Asthma (self-reported)	0.1	0.3	1.0	0.3	-0.6	-0.6	0.7	-0.0	0.5	0.2	0.5	-0.1	-1.0	-0.6	-0.6	-0.5
Age started oral contraceptive pill	0.1	0.2	0.6	0.3	0.3	-0.3	0.8	0.7	-0.5	-0.1	-0.5	0.1	-0.3	-0.1	-0.4	-0.2
Impedance of whole body	0.1	0.5	3.0	-0.6	-0.5	0.5	1.3	-1.0	0.2	-0.0	-0.1	-0.4	-1.7	-0.0	-0.2	0.4
Hair Pigment	0.0	1.1	2.2	-1.4	-0.6	-1.5	0.6	-0.5	-0.5	-1.3	-1.4	-1.3	-1.5	-0.3	-1.0	0.1
Tanning	0.0	0.6	3.3	0.2	0.0	1.2	0.3	0.4	1.8	0.1	0.9	0.3	1.0	0.7	0.3	-0.3

Hub : Genes

ABCC6

Models

Trait associations