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chr1:233,964,807-236,357,391

Best TWAS P=8.88e-20 · Best GWAS P=4.78e-19 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	B3GALNT2	0.21	0.26	lasso	3	0.26	8.0e-31	6.1	-6.2	6.5e-10	0.45	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	GGPS1	0.18	0.21	enet	34	0.24	1.1e-28	-8.8	-8.8	1.3e-18	0.87	0.01	0.99	FALSE
3	CommonMind	Brain Pre-frontal Cortex	LOC100506795	0.18	0.11	enet	42	0.10	9.3e-13	-5.0	5.8	5.5e-09	-0.07	0.97	0.03	FALSE
4	GTEx	Adipose Subcutaneous	TBCE	0.12	0.10	lasso	2	0.08	2.6e-07	-6.4	-6.7	1.7e-11	0.53	0.97	0.01	FALSE
5	GTEx	Adipose Subcutaneous	B3GALNT2	0.14	0.13	enet	10	0.11	3.8e-09	5.7	-6.0	2.7e-09	0.40	1.00	0.00	FALSE
6	GTEx	Artery Aorta	RP5-855F14.1	0.26	0.20	enet	14	0.24	1.2e-13	-5.3	5.1	3.1e-07	-0.09	0.94	0.06	FALSE
7	GTEx	Breast Mammary Tissue	B3GALNT2	0.21	0.14	enet	7	0.13	3.3e-07	6.2	-6.6	3.1e-11	0.48	0.99	0.00	FALSE
8	GTEx	Breast Mammary Tissue (Female)	B3GALNT2	0.12	0.12	enet	13	0.07	5.0e-03	6.0	-6.5	5.7e-11	0.46	0.10	0.06	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	TBCE	0.16	0.19	lasso	2	0.15	1.1e-05	6.1	-6.5	7.9e-11	0.48	0.33	0.10	FALSE
10	GTEx	Cells EBV-transformed lymphocytes	B3GALNT2	0.32	0.27	enet	9	0.27	1.7e-09	6.1	-6.1	1.1e-09	0.44	0.99	0.00	FALSE
11	GTEx	Cells Transformed fibroblasts	B3GALNT2	0.18	0.03	lasso	13	0.09	1.8e-07	6.3	-8.0	1.9e-15	0.66	0.46	0.54	FALSE
12	GTEx	Heart Atrial Appendage	TBCE	0.22	0.03	enet	10	0.02	5.3e-02	-6.8	-6.6	4.2e-11	0.57	0.13	0.06	FALSE
13	GTEx	Lung	TBCE	0.08	0.06	lasso	2	0.05	1.2e-04	-6.4	-6.5	8.2e-11	0.53	0.71	0.01	FALSE
14	GTEx	Muscle Skeletal	TBCE	0.07	0.05	enet	4	0.05	7.6e-06	-6.4	-7.2	5.9e-13	0.58	0.77	0.02	FALSE
15	GTEx	Nerve Tibial	TBCE	0.09	0.04	lasso	4	0.04	1.1e-03	-6.4	-7.1	1.4e-12	0.60	0.12	0.40	FALSE
16	GTEx	Nerve Tibial	B3GALNT2	0.31	0.28	enet	33	0.28	6.6e-20	6.1	-5.9	3.6e-09	0.37	1.00	0.00	FALSE
17	GTEx	Nerve Tibial	TOMM20	0.09	0.04	enet	8	0.06	7.0e-05	-7.1	-8.3	8.9e-17	0.83	0.23	0.75	FALSE
18	GTEx	Nerve Tibial	RP5-855F14.1	0.10	0.11	lasso	3	0.13	3.5e-09	-4.9	5.9	3.9e-09	-0.15	0.89	0.03	TRUE
19	GTEx	Testis	ARID4B	0.20	0.21	lasso	5	0.17	3.7e-08	-7.1	7.1	1.1e-12	-0.77	0.84	0.16	FALSE
20	GTEx	Thyroid	B3GALNT2	0.19	0.17	enet	30	0.16	6.7e-12	6.3	-6.0	1.9e-09	0.43	1.00	0.00	FALSE
21	GTEx	Vagina	TBCE	0.27	0.12	enet	10	0.10	3.2e-03	-6.4	-7.1	1.7e-12	0.54	0.25	0.08	FALSE
22	GTEx	Whole Blood	TBCE	0.06	0.03	enet	7	0.05	4.9e-05	-6.4	-6.5	8.5e-11	0.57	0.90	0.01	FALSE
23	GTEx	Whole Blood	B3GALNT2	0.10	0.05	enet	6	0.03	4.4e-04	6.0	-6.1	1.2e-09	0.43	0.67	0.01	FALSE
24	METSIM	Adipose	B3GALNT2	0.11	0.10	bslmm	332	0.10	1.4e-14	6.2	-6.8	9.4e-12	0.44	1.00	0.00	FALSE
25	METSIM	Adipose	TOMM20	0.05	0.00	bslmm	413	0.01	3.5e-03	-7.6	6.0	1.7e-09	-0.42	0.07	0.08	FALSE
26	NTR	Blood	B3GALNT2	0.06	0.05	lasso	4	0.05	3.3e-17	6.0	-6.5	6.0e-11	0.46	1.00	0.00	FALSE
27	NTR	Blood	GGPS1	0.03	0.03	lasso	3	0.03	5.0e-10	-8.9	9.1	8.9e-20	-0.99	0.01	0.99	TRUE
28	YFS	Blood	B3GALNT2	0.01	0.00	lasso	4	0.00	1.7e-02	-5.8	-8.0	8.9e-16	0.74	0.09	0.82	FALSE
29	YFS	Blood	GGPS1	0.08	0.09	enet	33	0.11	9.8e-33	-8.9	8.9	6.8e-19	-0.93	0.01	0.99	FALSE
30	YFS	Blood	RBM34	0.03	0.02	blup	386	0.02	1.0e-07	2.3	-5.5	3.7e-08	0.62	0.97	0.03	FALSE
31	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	B3GALNT2	0.04	0.01	blup	77	0.02	4.8e-03	6.1	-7.4	1.2e-13	0.55	0.09	0.62	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	B3GALNT2	0.13	0.14	lasso	3	0.13	2.0e-26	6.3	-6.3	3.7e-10	0.44	0.84	0.16	FALSE
33	The Cancer Genome Atlas	Colon Adenocarcinoma	B3GALNT2	0.11	0.08	blup	75	0.09	9.1e-06	6.3	-6.8	1.2e-11	0.45	0.54	0.24	FALSE
34	The Cancer Genome Atlas	Glioblastoma Multiforme	B3GALNT2	0.22	0.15	enet	17	0.17	6.7e-06	-6.1	-6.8	8.7e-12	0.48	0.25	0.69	FALSE
35	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	B3GALNT2	0.05	0.06	enet	12	0.07	2.2e-08	5.7	-6.9	4.6e-12	0.55	0.29	0.71	FALSE
36	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TBCE	0.04	0.05	enet	4	0.04	2.4e-05	-6.4	-6.4	1.2e-10	0.52	0.88	0.10	FALSE
37	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	B3GALNT2	0.17	0.32	lasso	4	0.31	1.2e-35	6.3	-6.3	2.5e-10	0.46	0.84	0.16	FALSE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TBCE	0.05	0.04	blup	58	0.04	2.2e-05	-6.2	-6.7	2.0e-11	0.56	0.86	0.06	FALSE
39	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	B3GALNT2	0.16	0.24	enet	17	0.24	9.2e-14	6.3	-7.2	5.2e-13	0.54	0.81	0.19	FALSE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	B3GALNT2	0.15	0.22	enet	17	0.22	3.1e-24	6.3	-7.1	1.5e-12	0.54	0.84	0.16	FALSE
41	The Cancer Genome Atlas	Lung Adenocarcinoma	B3GALNT2	0.07	0.11	lasso	3	0.10	3.2e-12	6.1	-6.2	5.7e-10	0.46	0.88	0.12	FALSE
42	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	B3GALNT2	0.04	0.03	lasso	3	0.03	3.6e-03	6.1	-6.6	4.9e-11	0.48	0.06	0.45	FALSE
43	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	B3GALNT2	0.08	0.05	enet	8	0.05	4.5e-03	6.2	-7.2	4.2e-13	0.50	0.09	0.27	FALSE
44	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RBM34	0.09	-0.01	blup	32	0.01	1.1e-01	2.7	6.4	1.4e-10	-0.64	0.01	0.22	FALSE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	B3GALNT2	0.03	0.00	blup	77	0.01	1.3e-02	-6.7	-6.0	2.3e-09	0.56	0.04	0.89	FALSE
46	The Cancer Genome Atlas	Prostate Adenocarcinoma	TBCE	0.07	0.04	blup	58	0.05	6.8e-06	-6.4	-5.6	2.1e-08	0.46	0.94	0.02	FALSE
47	The Cancer Genome Atlas	Rectum Adenocarcinoma	ARID4B	0.39	0.00	blup	70	0.05	2.7e-02	2.5	6.6	4.5e-11	-0.66	0.02	0.40	FALSE
48	The Cancer Genome Atlas	Soft Tissue Sarcoma	B3GALNT2	0.06	0.06	blup	75	0.05	7.5e-04	6.1	-6.7	2.1e-11	0.51	0.06	0.82	FALSE
49	The Cancer Genome Atlas	Stomach Adenocarcinoma	B3GALNT2	0.14	0.04	enet	14	0.08	2.1e-06	-6.7	-5.5	3.0e-08	0.43	0.16	0.76	FALSE
50	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ARID4B	0.13	-0.01	blup	70	0.08	8.2e-04	-6.7	-8.2	3.8e-16	0.88	0.04	0.82	FALSE
51	The Cancer Genome Atlas	Thyroid Carcinoma	B3GALNT2	0.11	0.15	lasso	6	0.15	2.5e-14	-6.1	-6.6	5.2e-11	0.56	0.66	0.34	FALSE
52	The Cancer Genome Atlas	Thyroid Carcinoma	GGPS1	0.05	0.01	enet	5	0.02	9.6e-03	-8.7	6.8	1.1e-11	-0.80	0.00	0.81	FALSE