TWAS hub - TBCE

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1240	0.0470	8.7e-05	0.096	NA	0.071	NA	0.083	3.0e-08	NA	2.0e-06	NA	2.6e-07
2	GTEx	Cells EBV-transformed lymphocytes	0.1620	0.0790	7.3e-03	0.194	NA	0.112	NA	0.153	6.4e-07	NA	1.7e-04	NA	1.1e-05
3	GTEx	Cells Transformed fibroblasts	0.2310	0.0630	1.7e-06	0.106	NA	0.144	NA	0.101	2.6e-08	NA	6.2e-11	NA	5.5e-08
4	GTEx	Heart Atrial Appendage	0.2160	0.0830	1.8e-03	0.027	NA	0.018	NA	0.008	2.2e-02	NA	5.3e-02	NA	1.4e-01
5	GTEx	Lung	0.0831	0.0384	5.0e-03	0.061	NA	0.038	NA	0.049	1.8e-05	NA	6.3e-04	NA	1.2e-04
6	GTEx	Muscle Skeletal	0.0748	0.0310	1.1e-03	0.046	NA	0.052	NA	0.040	2.2e-05	NA	7.6e-06	NA	8.5e-05
7	GTEx	Nerve Tibial	0.0851	0.0396	3.8e-03	0.042	NA	0.024	NA	0.038	6.0e-04	NA	7.9e-03	NA	1.1e-03
8	GTEx	Thyroid	0.1770	0.0530	3.2e-05	0.102	NA	0.075	NA	0.080	3.4e-08	NA	2.3e-06	NA	9.6e-07
9	GTEx	Vagina	0.2730	0.0900	5.7e-04	0.120	NA	0.097	NA	0.049	1.1e-03	NA	3.2e-03	NA	2.8e-02
10	GTEx	Whole Blood	0.0570	0.0250	2.3e-03	0.029	NA	0.045	NA	0.035	9.1e-04	NA	4.9e-05	NA	3.0e-04
11	METSIM	Adipose	0.0853	0.0292	2.3e-05	0.035	0.044	0.036	0.047	0.031	4.5e-06	2.7e-07	3.6e-06	1.3e-07	1.5e-05
12	YFS	Blood	0.1020	0.0225	1.7e-16	0.045	0.054	0.072	0.064	0.072	1.5e-14	4.3e-17	2.3e-22	4.2e-20	2.3e-22
13	TCGA	Breast Invasive Carcinoma	0.0358	0.0174	2.0e-05	0.022	0.017	0.019	NA	0.004	2.3e-05	1.8e-04	8.1e-05	NA	3.6e-02
14	TCGA	Glioblastoma Multiforme	0.2620	0.1090	1.3e-04	0.166	0.093	0.148	NA	0.125	9.7e-06	9.0e-04	2.9e-05	NA	1.3e-04
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0391	0.0188	9.3e-06	0.046	0.035	0.040	NA	0.022	6.8e-06	6.9e-05	2.4e-05	NA	1.3e-03
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0451	0.0230	3.7e-05	0.044	0.040	0.039	NA	0.021	8.9e-06	2.2e-05	3.0e-05	NA	2.0e-03
17	TCGA	Brain Lower Grade Glioma	0.0502	0.0274	5.7e-04	0.023	0.030	0.043	NA	0.036	1.0e-03	2.1e-04	1.2e-05	NA	5.1e-05
18	TCGA	Prostate Adenocarcinoma	0.0724	0.0378	4.2e-06	0.037	0.049	0.036	NA	0.046	9.2e-05	6.8e-06	1.0e-04	NA	1.3e-05
19	TCGA	Thyroid Carcinoma	0.1400	0.0530	5.1e-06	0.003	0.043	0.038	NA	0.025	1.5e-01	4.8e-05	1.2e-04	NA	1.6e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Qualifications: College or University degree	7.6	23.9	33.2	-5.8	-5.6	-4.8	-2.1	-5.6	-5.0	-5.5	-3.0	-5.0	-5.4	-4.4	-4.2	-5.4	-4.8	-5.7	-5.0	-4.8	-5.6	-3.2
Body Mass Index (BMI) (2010)	7.4	10.2	17.1	-3.0	-1.9	-4.1	-2.8	-3.4	-3.6	-3.1	-1.2	-3.5	-3.1	-3.1	-2.4	-3.2	-3.9	-3.4	-3.7	-3.0	-3.5	-3.3
Qualifications: CSEs or equivalent	7.3	9.6	14.8	3.4	3.8	3.7	2.3	3.1	3.1	3.1	1.4	2.8	3.0	3.5	2.2	3.3	3.0	3.2	3.0	3.5	3.6	2.7
Pain type(s) experienced in last month: Hip pain	5.7	7.2	11.0	-3.2	-2.8	-1.8	-1.9	-3.3	-3.1	-3.3	-1.5	-3.2	-3.1	-1.9	-2.6	-2.8	-2.6	-3.2	-2.9	-2.4	-2.8	-0.9
Number of incorrect matches in round	5.3	8.9	15.4	3.7	3.2	2.1	1.4	3.7	3.5	3.9	0.9	2.7	3.3	2.5	2.5	3.4	3.0	3.7	3.3	2.8	2.9	2.0
Breast cancer (self-reported)	5.0	6.0	10.9	-2.7	-2.7	-1.7	-0.3	-2.7	-1.8	-2.5	-2.8	-2.0	-2.8	-2.3	-2.6	-3.3	-1.2	-2.8	-2.3	-3.3	-2.5	-2.3
Exposure to tobacco smoke outside home	4.8	6.4	10.4	2.8	2.5	2.3	2.6	2.8	3.0	2.9	0.2	2.5	2.9	2.0	1.4	2.7	3.2	2.9	2.9	2.3	2.7	1.2
Asthma	4.6	9.1	24.1	-2.3	-1.0	-4.7	-0.8	-2.9	-2.5	-2.6	-2.6	-1.7	-2.4	-1.9	-3.0	-3.2	-3.6	-2.8	-3.6	-3.7	-3.7	-4.9
Asthma (self-reported)	4.5	8.9	24.0	-2.3	-1.0	-4.5	-0.7	-2.8	-2.5	-2.5	-2.5	-1.7	-2.4	-1.9	-3.0	-3.2	-3.6	-2.8	-3.6	-3.6	-3.7	-4.9
Tinnitus: Yes, but not now, but have in the past	4.4	4.7	7.0	-2.2	-1.8	-1.5	-0.4	-2.4	-2.3	-2.2	-1.3	-1.8	-2.6	-2.2	-1.4	-2.5	-2.6	-2.6	-2.6	-2.5	-2.4	-2.4
Medication: Lisinopril	3.8	4.9	8.5	-2.5	-2.2	-0.7	-2.3	-2.6	-2.9	-2.6	0.4	-2.7	-2.6	-1.9	-1.3	-2.6	-1.8	-2.6	-2.9	-1.5	-2.3	-1.2
Hypothyroidism (self reported)	3.7	8.5	13.5	-3.2	-2.9	-3.1	-1.4	-3.3	-2.6	-3.7	-1.8	-2.9	-3.1	-2.7	-2.5	-3.6	-2.5	-3.5	-3.2	-3.6	-2.7	-1.5
Respiratory disease	3.5	7.8	20.2	-2.0	-0.9	-4.5	-0.2	-2.6	-2.1	-2.4	-2.6	-1.5	-2.5	-2.0	-3.0	-2.9	-3.0	-2.5	-3.4	-3.2	-3.6	-4.4
Pain experienced in last month	3.4	5.7	9.6	2.7	2.7	1.2	1.9	2.6	2.6	2.6	0.9	3.1	3.1	2.3	2.7	2.5	1.9	2.8	2.5	1.6	2.6	1.5
Medication: Gliclazide	3.3	3.7	9.5	-1.4	-0.7	-3.1	-1.1	-1.8	-1.4	-1.7	-1.0	-2.3	-1.9	-1.9	-2.1	-2.0	-2.2	-1.9	-2.2	-2.2	-2.0	-2.3
Peak expiratory flow (PEF)	3.1	7.2	15.4	-3.4	-3.2	-1.3	-3.5	-3.3	-3.8	-3.5	2.5	-3.9	-3.1	0.4	1.1	-1.5	-1.8	-3.2	-3.0	-0.1	-1.5	1.7
Severe depression (siblings)	3.0	3.4	7.7	-1.4	-0.7	-1.8	-0.8	-1.7	-1.5	-1.5	-1.3	-1.6	-1.5	-2.5	-1.7	-2.3	-2.5	-1.7	-2.0	-2.4	-1.9	-2.8
Average weekly champagne plus white wine intake	3.0	4.1	7.2	-2.5	-2.4	-2.7	-0.9	-2.3	-2.0	-2.6	-1.3	-1.8	-1.9	-1.1	-1.9	-2.1	-2.3	-2.2	-1.8	-2.0	-2.2	-1.0
Fractured/broken bones in last 5 years	3.0	3.8	6.8	-1.9	-1.6	-0.9	-0.4	-2.2	-1.8	-2.2	-1.3	-2.5	-2.2	-1.3	-1.9	-2.6	-1.7	-2.4	-2.6	-1.9	-2.2	-2.1
Chronic bronchitis/emphysema (father)	2.9	3.4	6.4	2.1	2.1	2.5	0.8	2.0	1.7	2.0	0.8	2.1	1.8	0.9	1.2	2.0	2.1	2.0	1.9	2.2	2.2	1.5
Intelligence (Savage-Jansen 2018)	2.8	8.6	17.3	-3.9	-4.2	-3.3	-1.6	-3.5	-3.7	-3.8	-0.2	-3.3	-3.7	-1.2	-1.2	-2.4	-2.6	-3.5	-3.3	-2.0	-3.3	-0.6
Long-standing illness, disability or infirmity	2.7	4.2	7.8	-2.3	-2.1	-2.0	-2.2	-2.2	-2.7	-2.6	-0.1	-2.2	-2.8	-0.2	-1.5	-2.0	-1.4	-2.3	-2.6	-1.6	-2.3	-1.2
Lupus	2.6	3.9	8.0	-2.2	-2.2	-2.8	-1.2	-2.1	-2.2	-2.6	0.4	-1.9	-2.8	-1.3	-0.9	-2.3	-1.4	-2.2	-2.3	-1.7	-1.8	-1.0
Leg fat-free mass (right)	2.6	14.0	25.9	-3.7	-2.3	-3.9	-4.2	-4.3	-4.6	-4.4	0.6	-4.6	-4.2	-3.3	-1.7	-3.8	-3.8	-4.2	-5.1	-3.0	-3.6	-2.8
Leg predicted mass (right)	2.6	14.0	25.7	-3.8	-2.4	-3.9	-4.2	-4.3	-4.5	-4.4	0.5	-4.7	-4.2	-3.4	-1.8	-3.8	-3.7	-4.2	-5.1	-3.0	-3.6	-2.8
Type 2 Diabetes (T2D) (2018)	2.5	4.7	10.5	-2.5	-2.3	-2.4	-2.6	-2.5	-3.2	-2.7	1.1	-2.6	-2.8	-1.1	0.3	-1.7	-2.3	-2.5	-2.4	-1.4	-1.7	0.2
Mouth/teeth dental problems: Loose teeth	2.5	3.0	7.0	-1.2	-0.6	-2.6	-0.3	-1.6	-1.1	-1.3	-1.8	-1.0	-1.6	-2.1	-2.2	-1.9	-1.3	-1.6	-2.1	-2.1	-2.1	-2.4
Qualifications: A levels/AS levels or equivalent	2.4	5.2	7.8	-2.8	-2.6	-1.8	-1.7	-2.8	-2.2	-2.6	-1.6	-2.6	-2.7	-1.4	-1.8	-2.5	-1.9	-2.8	-2.5	-2.3	-2.7	-1.3
Financial situation satisfaction	2.4	2.9	6.8	1.8	1.1	2.1	2.6	2.0	2.0	1.9	-0.0	2.0	1.8	1.7	0.3	1.3	1.9	1.9	2.1	1.3	1.7	0.6
Supplements: Glucosamine	2.3	3.0	6.5	-1.7	-1.1	-2.3	-1.2	-2.0	-2.3	-1.9	-0.0	-2.2	-2.2	-1.0	-0.4	-1.5	-1.5	-2.0	-2.6	-1.1	-2.0	-1.2
Leg predicted mass (left)	2.3	12.2	22.1	-3.5	-2.2	-3.7	-4.1	-4.0	-4.4	-4.1	0.9	-4.5	-3.9	-3.0	-1.4	-3.4	-3.5	-3.9	-4.7	-2.6	-3.3	-2.4
Hair/balding pattern: Pattern 2	2.3	2.9	5.6	2.1	1.7	2.2	1.4	2.2	2.4	2.3	0.5	1.8	1.7	-0.1	1.2	1.2	1.6	2.1	2.0	1.3	1.5	0.7
Medication: Simvastatin	2.3	3.3	7.5	-2.1	-1.2	-2.0	-1.2	-2.5	-2.1	-2.3	-0.8	-1.9	-2.5	-0.2	-1.3	-1.9	-0.6	-2.4	-2.7	-1.2	-1.9	-1.4
Time employed in main current job	2.3	2.6	8.0	-1.1	-1.1	-2.8	-0.0	-1.2	-0.8	-1.1	-2.0	-0.9	-1.5	-1.8	-2.2	-1.8	-1.7	-1.2	-1.5	-2.1	-1.7	-2.2
Leg fat-free mass (left)	2.2	11.7	21.4	-3.4	-2.1	-3.7	-4.0	-3.9	-4.3	-4.0	0.9	-4.4	-3.8	-2.9	-1.4	-3.3	-3.4	-3.8	-4.6	-2.5	-3.2	-2.3
Hearing difficulty/problems with background noise	2.2	3.5	7.0	-1.8	-1.6	-1.8	-0.3	-1.9	-1.2	-1.9	-2.1	-1.3	-2.2	-0.7	-2.1	-2.4	-1.1	-2.0	-1.9	-2.6	-2.4	-2.3
Neck or shoulder pain in last month	2.2	3.2	4.6	-2.1	-1.9	-0.9	-1.8	-2.1	-2.1	-1.8	-0.6	-1.8	-1.8	-1.5	-1.4	-1.9	-2.1	-2.1	-1.9	-1.8	-2.0	-1.0
Had major operations	2.2	2.6	4.6	-1.6	-1.0	-0.7	-1.1	-2.0	-1.9	-1.8	-0.0	-1.4	-2.1	-1.9	-1.2	-2.1	-2.1	-2.0	-2.1	-1.2	-1.3	-1.4
Illnesses of father: Heart disease	2.2	3.1	7.7	1.6	1.5	1.7	0.3	1.6	0.8	1.5	2.8	1.1	1.3	2.0	2.4	1.8	0.8	1.5	1.3	2.6	2.2	2.5
Medication: Levothyroxine sodium	2.1	3.6	8.4	-2.4	-2.1	-1.6	-1.8	-2.4	-1.8	-2.9	-1.0	-1.9	-2.2	-1.0	-1.8	-2.0	-1.4	-2.5	-1.8	-1.8	-1.6	0.5
Alcohol usually taken with meals	2.1	3.4	5.6	-2.3	-1.6	-2.3	-1.3	-2.4	-1.8	-2.3	-1.0	-1.7	-2.0	-1.1	-1.6	-1.8	-2.0	-2.2	-1.9	-1.4	-2.2	-0.7
Suffer from ‘nerves’	2.1	3.3	10.2	2.1	1.8	0.9	3.2	2.0	3.1	2.0	-2.1	2.4	1.5	-0.0	-1.3	0.3	1.1	1.9	2.1	-0.1	1.0	-1.0
Whole body water mass	2.1	11.8	22.9	-3.5	-2.3	-3.2	-4.0	-4.0	-4.4	-4.1	1.2	-4.7	-4.0	-3.1	-1.2	-3.4	-3.2	-3.9	-4.8	-2.3	-3.1	-2.0
Neuroticism (2016)	2.0	2.8	6.6	-2.1	-2.4	-0.7	-1.0	-2.0	-1.9	-2.1	-0.9	-1.9	-2.6	-1.0	-1.2	-1.9	-0.8	-2.2	-2.0	-0.8	-1.8	-0.5
Qualifications: None of the above	2.0	4.2	7.8	2.6	2.0	1.4	0.2	2.8	2.1	2.6	1.0	1.6	2.3	2.1	1.5	2.5	2.6	2.7	2.0	1.9	1.9	0.9
Number of full brothers	2.0	2.5	5.9	2.1	2.4	0.5	1.9	1.8	2.2	1.7	-0.3	1.8	2.0	1.1	-0.1	1.3	1.9	1.8	1.5	1.3	1.2	0.2
Commuting to job workplace: Car/motor vehicle	2.0	2.3	7.6	1.9	1.7	2.8	1.9	1.8	1.8	1.8	0.2	0.9	1.6	0.2	0.5	1.2	0.9	1.8	1.4	1.5	1.7	-0.1
Illness, injury, bereavement, stress in last 2 years	2.0	2.5	4.6	-1.7	-1.7	-1.4	-0.5	-1.6	-1.2	-1.7	-1.2	-1.8	-1.3	-1.8	-1.7	-2.0	-1.8	-1.5	-1.1	-2.2	-1.3	-1.8
Whole body fat-free mass	2.0	11.4	21.8	-3.4	-2.3	-3.2	-3.9	-3.9	-4.3	-4.0	1.2	-4.6	-3.9	-2.9	-1.2	-3.3	-3.1	-3.9	-4.7	-2.2	-3.1	-1.9
Other serious medical condition/disability diagnosed by doctor	1.9	2.4	5.4	-1.9	-1.8	-0.0	-1.4	-2.0	-2.3	-2.1	1.4	-2.2	-2.0	-0.3	0.2	-1.6	-0.5	-2.2	-2.2	-0.2	-0.7	0.6
Worrier / anxious feelings	1.9	3.6	6.0	-2.1	-2.5	-1.7	-0.7	-1.9	-1.7	-1.9	-1.6	-1.8	-2.2	-1.5	-2.3	-2.2	-1.4	-2.0	-1.9	-1.8	-2.3	-1.6
Standing height	1.9	18.5	32.8	-5.4	-5.3	-3.5	-4.4	-5.2	-5.4	-5.7	0.9	-5.7	-5.4	-2.7	-1.2	-4.1	-2.9	-5.2	-5.1	-2.8	-4.0	0.2
Reason for reducing amount of alcohol drunk: Health precaution	1.9	2.2	5.2	-1.9	-2.3	-2.0	-1.2	-1.6	-1.0	-1.6	-1.4	-0.9	-1.7	-0.8	-1.5	-1.9	-0.8	-1.6	-1.2	-1.1	-1.9	-0.9
Migraine (self-reported)	1.9	2.4	4.8	-1.9	-2.0	-1.3	-0.6	-1.7	-1.9	-1.6	-0.1	-1.4	-1.8	-2.2	-0.8	-1.3	-2.2	-1.8	-1.4	-1.4	-1.6	-0.2
Medication for cholesterol	1.9	2.8	5.1	2.0	2.2	1.3	1.2	1.9	1.5	2.1	1.2	1.7	2.3	0.8	1.9	1.9	0.7	1.8	1.8	1.6	2.0	0.7
Number of self-reported non-cancer illnesses	1.9	3.3	6.4	-2.2	-1.8	-0.8	-1.7	-2.3	-2.4	-2.4	-0.3	-2.2	-2.5	-1.0	-1.2	-1.8	-1.4	-2.4	-2.2	-1.2	-1.6	-0.4
Basal metabolic rate	1.9	10.8	20.7	-3.3	-2.0	-3.2	-3.8	-3.8	-4.2	-3.9	1.2	-4.4	-3.8	-2.9	-1.3	-3.2	-3.2	-3.7	-4.5	-2.2	-3.0	-2.1
Trunk fat-free mass	1.8	10.2	20.9	-3.3	-2.4	-2.8	-3.6	-3.7	-4.2	-3.9	1.6	-4.6	-3.8	-2.7	-0.8	-3.1	-2.8	-3.7	-4.5	-1.8	-2.8	-1.3
Trunk predicted mass	1.8	10.1	20.2	-3.3	-2.4	-2.8	-3.5	-3.7	-4.2	-3.9	1.5	-4.5	-3.8	-2.7	-0.8	-3.1	-2.8	-3.7	-4.5	-1.9	-2.8	-1.2
Arm predicted mass (right)	1.8	9.1	17.6	-3.0	-2.1	-2.5	-3.7	-3.4	-3.9	-3.5	1.5	-4.2	-3.6	-2.5	-1.0	-3.0	-2.8	-3.4	-4.2	-1.9	-2.7	-1.6
Commuting to job workplace: Public transport	1.8	2.1	4.4	-1.5	-0.9	-2.1	-1.1	-1.7	-1.6	-1.6	-0.7	-0.9	-1.4	-1.0	-1.5	-1.7	-1.6	-1.7	-1.6	-2.1	-1.4	-1.0
Alzheimer’s Disease (in father)	1.7	1.8	5.3	-1.6	-1.6	-0.7	-1.2	-1.6	-1.9	-1.7	0.3	-2.3	-1.9	-0.8	-0.5	-1.1	-0.6	-1.6	-1.6	-0.8	-1.3	-0.1
Rheumatoid Arthritis	1.7	2.3	5.5	1.9	1.9	-0.1	1.8	1.8	2.3	1.9	-1.1	2.4	1.8	0.7	-0.2	1.1	1.7	1.7	1.7	0.6	0.9	0.0
Townsend deprivation index at recruitment	1.7	2.3	4.9	1.8	1.9	-0.5	0.1	1.8	1.1	1.9	1.2	1.6	2.1	0.1	2.2	2.0	0.3	1.7	1.7	0.7	2.0	1.1
Fluid intelligence score	1.7	3.5	7.7	-2.3	-2.0	-1.0	-1.5	-2.4	-2.8	-2.3	-0.1	-2.3	-2.4	-1.1	-0.9	-1.8	-1.1	-2.5	-2.6	-0.9	-1.9	-0.4
Arm fat-free mass (right)	1.7	8.5	17.4	-2.8	-1.8	-2.5	-3.7	-3.3	-3.8	-3.4	1.6	-4.1	-3.5	-2.4	-0.8	-2.8	-2.7	-3.2	-4.2	-1.8	-2.6	-1.7
Handedness (chirality/laterality): Left-handed	1.7	2.1	10.4	1.0	1.3	0.1	3.1	0.8	1.3	1.1	-3.2	1.1	0.9	1.1	-1.8	0.4	0.1	0.8	0.9	-0.7	-0.5	-2.1
Alcohol drinker status: Never	1.7	2.0	4.2	-1.6	-1.9	-0.2	-0.2	-1.5	-0.6	-1.8	-1.0	-1.5	-1.8	-1.3	-2.1	-2.0	0.4	-1.7	-1.5	-0.6	-1.6	-1.1
Height	1.6	31.1	51.8	-6.7	-6.5	-5.1	-6.6	-6.5	-7.2	-7.1	0.5	-7.1	-6.5	-3.7	-1.7	-5.0	-4.2	-6.4	-6.7	-4.5	-5.6	-0.5
Number of treatments/medications taken	1.6	2.9	6.0	-1.9	-1.8	-0.9	-2.4	-1.9	-2.4	-2.0	0.3	-2.4	-2.2	-1.0	-1.0	-1.4	-1.3	-1.9	-1.9	-1.0	-1.6	-0.0
Hand grip strength (right)	1.6	4.5	11.8	-2.4	-2.2	-1.5	-2.1	-2.4	-3.0	-2.5	2.2	-3.4	-2.0	-1.7	1.4	-1.6	-2.2	-2.4	-2.5	-0.7	-1.1	0.2
Nervous feelings	1.6	3.0	8.7	1.8	1.2	1.1	3.0	1.9	2.8	1.9	-2.6	2.4	1.6	0.3	-1.1	0.4	1.6	1.8	2.0	-0.6	0.7	-1.0
Number of operations (self-reported)	1.6	2.4	4.9	-2.0	-1.8	-0.4	-0.7	-2.1	-2.1	-2.2	0.7	-1.6	-2.1	-0.7	0.2	-1.9	-1.4	-2.1	-1.9	-1.1	-0.9	0.5
Pack years of smoking	1.6	2.3	6.5	-0.9	-0.3	-2.5	-0.5	-1.1	-1.3	-1.2	-0.7	-1.5	-1.4	-1.0	-0.8	-1.5	-1.7	-1.2	-2.0	-2.3	-2.0	-2.4
Verbal and Numeric Reasoning (VNR)	1.5	3.5	8.2	-2.2	-2.0	-1.9	-1.6	-2.3	-2.9	-2.3	1.1	-2.7	-2.5	-0.2	0.2	-1.0	-1.3	-2.2	-2.6	-0.3	-1.7	0.6
Average weekly spirits intake	1.5	1.8	5.0	1.6	2.2	0.8	-1.0	1.2	0.5	1.3	1.9	0.9	0.9	1.1	2.0	1.6	0.9	1.2	0.1	2.1	1.3	0.4
Impedance of leg (right)	1.5	7.2	13.9	2.0	0.6	3.7	2.7	2.8	2.7	2.7	0.4	2.2	2.5	3.0	1.7	2.8	3.0	2.7	3.7	2.8	2.7	3.5
Birth weight	1.5	3.3	16.6	-1.7	-1.3	-1.9	-4.1	-1.7	-2.9	-1.7	2.0	-1.9	-1.4	-0.7	1.0	-0.5	-1.6	-1.6	-2.1	0.0	-1.5	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.2	8.2	1.3	1.0	0.9	0.7	1.5	0.8	1.4	2.1	1.0	1.6	1.6	2.9	2.7	1.8	1.5	1.7	2.3	1.8	2.9
Coronary Artery Disease (CAD)	1.4	1.7	4.0	-1.3	-0.9	-1.8	-1.8	-1.4	-2.0	-1.1	1.7	-1.9	-1.2	0.2	1.1	-0.4	-1.2	-1.1	-1.3	-0.6	-0.7	0.6
Weight	1.4	6.9	14.1	-2.4	-1.1	-2.5	-3.4	-3.0	-3.2	-3.0	0.7	-3.3	-2.9	-2.0	-1.4	-2.5	-2.7	-2.9	-3.8	-1.8	-2.4	-2.3
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	5.4	-1.9	-1.9	-1.6	-1.2	-1.9	-1.6	-2.3	-0.8	-1.7	-2.1	-1.3	-1.1	-1.9	-1.3	-2.0	-1.8	-1.8	-1.6	0.1
Eye problems/disorders: Cataract	1.4	1.7	5.3	0.7	-0.2	2.3	0.5	1.1	1.5	1.0	-0.5	1.3	0.5	1.6	-0.1	1.5	1.7	1.1	1.5	2.2	0.6	1.6
Arm fat-free mass (left)	1.4	7.0	15.0	-2.5	-1.4	-2.2	-3.3	-3.0	-3.5	-3.0	1.3	-3.8	-3.1	-2.4	-1.0	-2.6	-2.2	-2.9	-3.9	-1.6	-2.4	-1.8
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.9	-1.5	-1.7	-1.4	-0.5	-1.4	-1.8	-1.6	0.3	-1.4	-2.0	-0.1	-0.3	-1.2	-0.7	-1.3	-1.4	-0.8	-1.1	0.1
Sitting height	1.3	9.1	17.3	-3.4	-3.3	-4.2	-3.1	-3.3	-3.7	-3.5	0.1	-3.5	-3.3	-2.6	-0.9	-2.5	-2.4	-3.3	-3.5	-2.9	-3.4	-0.8
Relative age of first facial hair	1.2	2.5	5.2	1.6	1.0	1.8	2.2	1.8	2.2	1.8	0.1	1.4	1.8	1.2	1.1	1.5	1.2	1.8	2.3	1.3	1.8	0.6
Medication: Metformin	1.2	1.7	3.2	-1.3	-1.0	-1.5	-1.7	-1.3	-1.8	-1.4	0.2	-1.8	-1.7	-0.2	-0.5	-1.0	-1.3	-1.3	-1.6	-1.1	-1.5	-0.4
Pack years adult smoking proportion	1.2	1.8	5.1	-0.6	-0.0	-2.2	-0.2	-0.9	-1.2	-0.9	-0.3	-1.5	-1.3	-0.9	-0.5	-1.2	-1.6	-1.0	-1.9	-1.9	-1.8	-2.3
Diabetes (self-reported)	1.2	1.9	3.8	-1.4	-0.9	-1.6	-1.9	-1.5	-1.9	-1.6	0.6	-1.6	-1.6	-1.0	0.2	-1.1	-1.6	-1.5	-1.6	-1.3	-1.2	-0.2
Hair/balding pattern: Pattern 4	1.2	3.0	7.3	-2.3	-2.1	-2.7	-0.6	-2.3	-1.9	-2.3	-1.4	-1.3	-1.9	0.6	-1.1	-1.3	-0.5	-2.2	-2.0	-1.5	-1.8	-0.4
Hypertension (Self-reported)	1.2	3.2	4.7	-2.1	-2.0	-2.0	-1.1	-2.0	-1.7	-2.1	-0.7	-1.9	-2.2	-1.4	-2.0	-2.1	-0.6	-2.0	-1.9	-1.9	-1.8	-0.9
Medication: Paracetamol	1.2	1.8	3.7	-1.4	-0.9	-1.4	-1.2	-1.5	-1.1	-1.4	-1.1	-0.7	-1.3	-1.2	-1.6	-1.4	-1.5	-1.4	-1.3	-1.9	-1.5	-1.1
Cholesterol lowering medication	1.2	1.7	3.9	-1.4	-1.0	-1.6	-0.6	-1.6	-1.0	-1.6	-0.9	-1.0	-2.0	0.4	-1.4	-1.5	-0.9	-1.5	-1.6	-1.5	-1.2	-1.0
Arm predicted mass (left)	1.2	6.0	13.0	-2.2	-1.1	-2.0	-3.2	-2.8	-3.2	-2.8	1.4	-3.6	-2.8	-2.3	-0.7	-2.4	-2.2	-2.7	-3.6	-1.4	-2.0	-1.5
Schizophrenia vs Biploar Disorder	1.1	1.5	3.0	1.3	0.8	1.1	0.6	1.4	0.9	1.5	0.9	0.9	1.4	-0.1	1.4	1.2	1.1	1.2	1.3	1.7	1.5	1.7
BMI	1.1	6.1	12.5	-2.1	-0.7	-2.4	-3.0	-2.7	-3.1	-2.4	0.9	-2.9	-2.4	-2.0	-1.2	-2.2	-3.5	-2.6	-3.5	-1.7	-2.3	-2.7
Impedance of leg (left)	1.1	5.4	11.1	1.9	0.5	3.3	2.4	2.5	2.5	2.4	-0.1	2.2	2.3	2.4	1.3	2.4	2.5	2.4	3.3	2.1	2.2	2.8
Happiness	1.1	1.4	6.5	-0.2	-1.4	-0.4	2.5	0.5	1.3	0.2	-2.5	1.3	0.3	0.8	-1.5	-0.5	0.3	0.4	1.3	-1.1	-0.7	-0.0
Lung cancer (father)	1.1	1.3	3.9	-1.2	-1.2	-1.2	-0.6	-1.3	-1.7	-1.0	0.3	-2.0	-1.8	-0.8	-0.0	-0.5	-0.2	-1.3	-1.6	-0.1	-1.4	-0.5
Pulse wave peak to peak time	1.1	1.2	3.3	-1.0	-1.4	-1.7	-0.7	-0.7	-0.6	-0.7	-1.6	-0.1	-0.6	-1.8	-1.1	-0.6	-1.0	-0.6	-0.4	-1.7	-1.4	-1.3
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.4	4.5	1.3	1.5	0.2	0.7	1.2	0.5	1.4	1.7	1.1	1.0	1.0	2.1	1.7	-0.3	1.2	0.8	1.1	0.9	0.8
Back pain experienced in last month	1.1	1.7	4.4	-1.6	-1.3	-0.3	-1.0	-1.6	-0.9	-1.7	-1.2	-1.1	-1.6	-0.4	-2.1	-1.5	-0.8	-1.6	-1.3	-0.7	-1.5	-0.6
Ever had prostate specific antigen (PSA) test	1.1	1.2	4.3	-1.6	-2.1	-1.9	-1.1	-1.2	-0.8	-1.4	-0.8	-0.5	-1.2	0.3	-0.5	-1.0	-0.4	-1.2	-0.7	-1.0	-1.0	0.2
Basal cell carcinoma (self-reported)	1.1	1.4	3.6	-1.5	-1.5	-1.1	-1.2	-1.3	-1.9	-1.4	0.8	-1.1	-1.7	-0.5	0.0	-0.6	-1.0	-1.2	-1.2	-0.1	-1.1	0.6
Bipolar Disorder (2011)	1.0	1.0	4.9	-0.2	0.5	-0.3	-1.9	-0.3	-0.9	-0.3	2.2	-0.4	0.3	1.2	2.0	1.0	-0.7	-0.0	-0.3	0.8	0.2	0.8
Ulcerative Colitis	1.0	1.5	4.5	-1.5	-2.0	-2.1	-0.7	-1.2	-1.5	-1.4	0.5	-1.3	-1.6	-0.5	-0.4	-0.6	-1.5	-1.1	-0.9	-0.5	-1.1	0.3
Blood Eosinophil Count	1.0	7.5	19.3	-2.3	-1.8	-2.5	-0.4	-2.6	-1.8	-2.6	-2.8	-2.0	-2.8	-2.3	-4.4	-3.6	-2.1	-2.6	-2.7	-3.2	-3.4	-3.6
Sensitivity / hurt feelings	1.0	1.7	5.9	-0.4	-0.3	-0.3	0.7	-0.6	-0.1	-0.4	-2.3	-0.3	-1.0	-2.2	-2.1	-1.7	-0.5	-0.9	-1.0	-1.5	-1.6	-2.4
Forced expiratory volume in 1-second (FEV1)	1.0	3.2	7.1	-2.0	-2.0	-0.9	-2.4	-1.9	-2.4	-2.2	2.4	-2.7	-1.7	0.5	1.6	-0.3	-0.8	-1.8	-1.7	0.4	-0.8	2.3
Medication: Cholesterol lowering	1.0	1.6	4.6	-1.5	-1.1	-2.1	-1.6	-1.6	-1.8	-1.6	-0.0	-1.6	-1.5	0.5	-0.5	-1.0	-0.3	-1.4	-1.3	-0.5	-1.1	0.0
Loud music exposure frequency	1.0	1.1	6.2	-1.6	-2.5	-0.1	-0.6	-1.1	-0.8	-1.2	-0.7	-1.2	-1.2	-0.1	-0.6	-1.1	-0.3	-1.1	-0.2	-0.9	-0.7	0.5
Chronic bronchitis/emphysema (mother)	1.0	1.2	3.7	-0.9	-1.0	-1.8	-1.5	-0.9	-1.3	-0.9	0.4	-1.1	-0.8	-0.3	0.3	-0.8	-1.9	-1.0	-1.2	-1.2	-1.1	-0.3
Diabetes diagnosed by doctor	1.0	1.7	3.3	-1.2	-0.5	-1.8	-1.5	-1.4	-1.8	-1.5	0.6	-1.5	-1.6	-0.7	0.1	-1.0	-1.7	-1.4	-1.8	-1.1	-1.1	-0.5
Qualifications: nursing, teaching	1.0	1.5	3.1	-1.8	-1.7	-0.6	-0.4	-1.7	-1.5	-1.7	-0.1	-1.1	-1.7	-0.5	-0.7	-1.1	-1.0	-1.7	-0.9	-1.0	-0.8	1.0
Alcohol drinker status: Previous	1.0	1.1	3.3	0.8	0.1	1.2	-0.1	1.0	0.9	0.8	0.7	0.6	1.2	1.1	1.3	0.8	1.7	1.0	1.1	0.9	1.2	1.8
Medication for hormone replacement therapy	0.9	1.0	2.6	-1.3	-1.6	-0.8	-1.0	-1.1	-1.0	-1.3	-0.5	-1.3	-1.0	-0.3	-0.5	-1.1	-1.3	-1.1	-0.7	-0.9	-1.1	-0.0
Pain all over the body in last month	0.9	0.9	2.0	1.3	1.3	-0.7	0.4	1.2	0.3	1.1	1.4	1.1	1.0	0.1	1.4	1.1	0.2	1.3	0.8	0.4	1.1	0.1
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.8	-0.9	-0.5	-1.6	-0.1	-0.9	-0.2	-1.0	-1.1	-0.4	-0.7	-0.3	-1.7	-1.2	-1.6	-0.8	-0.7	-1.2	-1.2	-1.9
Comparative height size at age 10	0.9	5.1	10.8	-2.6	-2.2	-2.7	-3.3	-2.7	-3.0	-2.9	1.2	-2.9	-2.4	-0.2	0.1	-1.8	-2.0	-2.5	-3.0	-1.3	-1.8	0.1
Age at last live birth	0.9	1.3	4.6	-1.0	-0.5	-1.5	-1.1	-1.3	-1.4	-0.9	0.4	-0.9	-0.7	-2.2	-0.7	-1.0	-1.6	-1.2	-1.3	-0.9	-0.9	-1.1
Tinnitus: Yes, now most or all of the time	0.9	1.0	3.3	-1.5	-1.8	-1.2	0.1	-1.1	-0.6	-1.2	-1.2	-0.2	-1.1	0.5	-0.3	-0.7	-0.6	-1.0	-0.3	-1.8	-1.2	-0.1
Worry (Nagel 2018)	0.8	1.6	5.9	1.4	0.8	0.4	2.4	1.5	2.0	1.5	-1.3	1.8	0.8	-0.2	-0.5	0.3	1.4	1.5	1.5	0.0	0.6	-0.6
Primary Biliary Cirrhosis	0.8	1.2	2.0	-1.1	-0.9	-0.6	-1.0	-1.2	-1.2	-1.3	-0.2	-0.9	-1.1	-0.9	-0.9	-1.3	-1.2	-1.2	-1.4	-0.8	-1.4	-1.0
Heel T-Score	0.8	6.0	18.7	3.0	2.8	1.3	2.6	3.0	2.8	3.4	-0.4	4.3	3.6	-0.9	1.3	2.2	0.6	2.9	3.0	0.4	2.1	-0.3
Cardiovascular Disease	0.8	2.8	5.0	-2.1	-2.1	-1.1	-1.7	-2.0	-2.0	-2.0	1.1	-2.2	-1.9	-0.8	-1.0	-2.0	-1.1	-2.1	-1.9	-1.1	-1.2	-0.4
Trunk fat mass	0.8	3.5	9.2	-1.7	-0.6	-1.9	-3.0	-2.1	-2.3	-2.0	0.2	-2.2	-2.0	-0.9	-1.1	-1.6	-2.1	-2.0	-2.6	-1.5	-1.7	-1.9
Hip circumference	0.8	3.5	7.0	-1.4	-0.2	-2.0	-1.8	-2.0	-1.9	-1.9	-0.3	-2.0	-2.0	-1.5	-1.9	-1.8	-1.9	-1.9	-2.6	-1.8	-1.9	-2.6
Medication: Lansoprazole	0.8	0.9	3.2	-1.1	-1.2	-1.0	-1.4	-0.9	-0.9	-1.1	-0.6	-0.8	-0.6	1.8	0.1	0.1	-0.2	-1.0	-0.8	-0.4	-1.3	0.5
Prospective memory result	0.8	1.0	3.5	0.5	-0.1	0.7	0.6	0.9	1.4	0.6	0.1	0.8	1.0	0.7	0.9	1.2	0.7	1.0	1.9	1.1	1.4	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	7.5	-1.6	-1.7	-0.5	-2.3	-1.4	-2.2	-1.6	2.7	-2.4	-1.2	0.6	1.8	0.2	-0.7	-1.4	-1.2	0.8	-0.2	2.7
Commuting to job workplace: Walk	0.8	0.8	3.8	-0.6	-1.2	-0.2	-1.1	-0.3	-0.7	-0.8	1.7	-0.4	-0.8	1.1	1.0	0.1	1.1	-0.2	-0.2	0.6	-0.1	2.0
Illnesses of father: None of the above (group 1)	0.8	1.0	5.2	-0.1	0.1	-0.9	1.4	-0.2	0.7	-0.1	-2.3	0.0	0.2	-1.0	-1.6	-0.7	0.0	-0.1	0.2	-1.5	-0.5	-1.9
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	4.7	0.2	-0.4	2.2	0.4	0.5	0.4	0.2	0.7	0.2	0.3	1.2	0.5	0.8	1.6	0.5	1.1	1.4	1.2	1.8
Bipolar Disorder or Schizophrenia	0.7	1.6	2.7	-1.2	-0.7	-0.8	-1.0	-1.4	-1.6	-1.2	-0.7	-1.6	-1.0	-1.2	-1.5	-1.3	-1.3	-1.4	-1.6	-1.1	-1.4	-1.4
Prostate Cancer	0.7	1.0	2.9	-1.4	-1.5	-1.7	0.0	-1.1	-1.0	-1.2	-0.5	-1.0	-0.7	-0.5	-0.7	-0.7	-1.0	-1.1	-0.6	-1.0	-0.7	-0.2
Taking other prescription medications	0.7	1.1	2.6	-1.3	-1.6	-0.5	-1.5	-1.1	-1.3	-1.3	-0.1	-1.3	-1.4	-0.4	-0.8	-0.7	-0.6	-1.2	-0.9	-0.2	-1.2	0.1
High blood pressure	0.7	1.9	2.9	-1.6	-1.6	-1.6	-1.1	-1.5	-1.4	-1.7	-0.2	-1.6	-1.7	-0.8	-1.4	-1.5	-0.3	-1.6	-1.5	-1.5	-1.4	-0.5
Multivitamins +/- minerals	0.7	0.9	3.3	0.4	-0.1	0.5	0.1	0.8	0.5	0.5	1.4	0.7	0.7	1.3	1.5	1.0	-0.7	0.8	1.3	1.0	1.0	1.8
Breastfed as a baby	0.7	0.9	6.6	0.6	0.2	1.3	0.4	0.7	0.7	0.5	-0.0	0.7	0.4	0.9	0.6	0.8	2.6	0.8	0.8	0.7	0.9	1.6
Tense / ‘highly strung’	0.7	1.2	5.6	1.3	1.3	-0.1	2.4	1.1	1.5	1.3	-1.2	1.5	0.8	0.8	-0.1	0.4	0.8	1.1	0.9	0.2	0.4	-0.9
Gout (self-reported)	0.7	1.0	3.4	-1.1	-0.9	-0.1	-1.9	-1.2	-1.2	-1.1	-0.1	-1.4	-1.1	0.1	-0.5	-0.9	-0.6	-1.3	-1.1	-0.9	-0.7	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.9	-0.7	-1.2	1.0	-1.5	-0.4	-0.7	-0.8	1.7	-0.6	-0.6	0.9	0.9	0.2	-0.1	-0.4	-0.1	1.2	0.2	1.1
Mood swings	0.7	1.3	7.2	0.7	0.1	-0.5	2.7	0.9	1.4	0.8	-2.0	1.6	0.4	-0.7	-1.8	-0.4	0.0	0.7	0.8	-0.9	-0.0	-1.1
Vascular/heart problems diagnosed by doctor	0.7	1.9	4.0	1.6	1.4	2.0	1.3	1.6	1.6	1.6	0.1	1.6	1.8	0.7	1.2	1.4	0.2	1.6	1.6	1.3	1.4	0.5
Bipolar Disorder (2018)	0.6	1.0	3.2	-0.8	-0.1	-1.1	-0.7	-0.9	-0.8	-0.7	-0.7	-1.2	-0.8	-0.4	-1.0	-0.8	-1.3	-0.8	-1.0	-1.3	-1.2	-1.8
Depression (Nagel 2018)	0.6	0.8	4.7	0.9	1.1	1.4	2.2	0.6	1.1	0.7	0.0	1.3	0.7	0.1	-0.2	-0.3	0.7	0.6	0.7	0.4	1.3	-0.1
Crohns Disease (2012)	0.6	0.9	5.5	-0.5	-0.4	0.2	-1.0	-0.5	-1.2	-0.7	2.3	-1.4	-0.9	0.3	1.1	-0.5	-1.8	-0.5	-0.8	0.7	-0.1	0.2
Fasting Glucose	0.6	0.7	1.4	-0.9	-0.4	-0.8	-0.0	-1.1	-1.0	-1.2	-0.8	-0.7	-1.2	-0.9	-1.0	-0.5	-0.4	-0.9	-1.2	-0.3	-0.6	-0.6
Diabetes (mother)	0.6	0.7	1.7	-0.8	-0.3	-0.4	-0.5	-1.2	-1.1	-0.9	0.3	-1.2	-0.8	-1.3	-0.6	-0.9	-1.2	-1.1	-1.2	-0.1	-0.2	-0.2
Waist circumference	0.6	2.1	5.5	-0.8	0.5	-1.8	-2.0	-1.4	-1.7	-1.2	0.4	-1.5	-1.4	-1.1	-0.8	-1.0	-1.9	-1.3	-2.3	-0.9	-1.3	-2.3
Forced vital capacity (FVC)	0.6	2.5	5.1	-1.8	-1.8	-1.0	-2.0	-1.6	-2.2	-1.9	2.2	-2.1	-1.3	-0.1	1.6	-0.2	-1.1	-1.6	-1.5	0.3	-0.8	2.0
Financial difficulties in last 2 years	0.6	0.9	2.7	1.0	1.2	0.3	-0.2	0.9	0.1	1.3	1.6	0.6	1.0	0.5	1.6	1.2	0.1	0.9	0.2	1.1	0.8	0.5
Pulse wave Arterial Stiffness index	0.6	0.7	2.2	0.7	1.0	1.3	0.4	0.3	0.3	0.3	1.4	-0.2	0.2	1.5	0.9	0.3	0.8	0.3	-0.0	1.3	1.1	1.2
Arm fat mass (right)	0.6	2.3	5.6	-0.9	0.3	-1.8	-2.2	-1.5	-1.8	-1.3	0.5	-1.7	-1.4	-0.9	-1.0	-1.3	-2.0	-1.4	-2.4	-1.0	-1.3	-2.4
Pulse wave reflection index	0.6	0.7	3.3	0.5	0.2	1.8	0.7	0.5	0.7	0.4	0.5	-0.1	0.4	0.7	0.4	0.3	1.2	0.4	0.7	1.5	0.9	1.5
Number of children fathered	0.6	0.7	2.9	0.5	0.7	1.1	0.6	0.6	0.4	0.5	0.8	0.5	0.6	1.7	0.5	1.1	0.1	0.6	0.8	1.2	0.8	1.2
Arm fat mass (left)	0.6	2.4	5.7	-0.9	0.3	-1.9	-2.1	-1.5	-1.8	-1.4	0.5	-1.6	-1.5	-1.0	-1.0	-1.3	-1.9	-1.4	-2.3	-1.1	-1.3	-2.4
Medication: Blood pressure	0.6	1.1	3.2	-1.2	-1.8	-0.5	-1.6	-0.9	-1.0	-1.2	0.4	-0.9	-1.8	-0.6	-1.1	-1.1	0.6	-0.9	-1.1	-0.5	-1.0	0.5
Supplements: Fish oil (including cod liver oil)	0.6	0.7	2.2	0.8	0.6	0.7	-0.2	0.9	0.1	0.8	1.4	0.0	0.1	0.9	1.2	0.9	0.6	0.8	0.7	0.9	1.1	1.5
Ovarian Cancer	0.5	0.7	2.0	0.7	0.5	0.7	0.6	0.8	0.3	0.9	1.0	0.7	0.9	1.4	1.0	1.1	0.1	0.9	1.0	1.1	0.9	0.8
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.6	-0.5	-0.2	-1.0	-1.0	-0.7	-0.9	-0.7	-0.1	-0.6	-1.0	0.9	-0.3	-0.4	-0.5	-0.7	-1.2	-0.7	-1.1	-0.5
Relative age voice broke	0.5	0.8	2.4	0.5	0.2	-1.1	1.5	0.8	1.5	0.7	-1.5	1.3	0.8	0.2	0.1	0.2	0.1	0.8	1.0	-0.9	-0.1	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.0	3.9	1.2	0.8	0.3	0.5	1.3	0.7	1.6	0.2	2.0	1.6	-0.3	0.6	1.3	0.4	1.2	1.0	0.3	0.8	-0.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	3.2	-0.2	-0.4	-0.8	1.0	-0.2	0.4	-0.3	-1.8	0.2	-0.1	0.5	-1.5	-0.9	-0.1	-0.3	0.0	-1.2	-0.4	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	3.5	1.5	1.1	-0.0	0.4	1.5	0.8	1.9	0.3	1.7	1.8	-0.8	0.6	1.4	0.3	1.3	1.0	0.0	0.9	-0.8
Mouth/teeth dental problems	0.5	0.8	3.3	1.0	1.2	0.7	1.8	0.9	1.0	1.0	0.0	0.5	1.3	-0.5	0.4	1.0	0.0	1.0	1.1	0.4	1.0	-0.1
Father’s age at death	0.5	0.7	2.6	1.2	1.6	-0.0	-0.1	0.9	0.7	1.0	0.4	0.6	1.0	-0.9	0.8	1.0	1.3	1.0	0.6	0.2	0.5	0.4
Depression (self-reported)	0.5	0.6	1.8	1.2	1.4	0.3	1.2	1.0	0.9	0.9	-0.4	0.6	0.5	0.6	-0.0	0.3	0.6	0.9	0.1	0.2	0.1	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	4.8	1.0	1.1	0.1	2.2	0.8	0.9	0.8	0.1	0.8	0.4	-0.8	0.1	-0.0	0.4	0.9	0.6	0.3	0.8	-0.6
Birth weight of first child	0.5	0.9	2.7	-1.2	-1.6	-0.3	-1.2	-1.0	-1.2	-0.9	0.2	-1.4	-0.9	-1.1	0.5	-0.6	-0.6	-1.1	-0.8	-0.4	-0.8	0.8
Headache pain in last month	0.5	0.9	2.7	-1.2	-1.6	-0.2	0.1	-0.9	-0.5	-1.0	-1.1	-0.3	-0.8	-1.2	-1.5	-1.1	-1.3	-0.9	-0.2	-1.1	-0.8	-0.3
Forced vital capacity (FVC), Best measure	0.5	1.9	4.6	-1.6	-1.7	-0.8	-1.6	-1.4	-2.0	-1.6	2.1	-2.1	-1.1	0.1	1.3	-0.2	-1.0	-1.3	-1.1	0.4	-0.4	2.0
Worry too long after embarrassment	0.5	0.9	4.4	-0.3	-0.4	-0.1	1.1	-0.3	0.4	-0.2	-2.1	0.4	-0.4	-0.8	-1.6	-1.1	-0.3	-0.5	-0.6	-1.3	-1.1	-1.8
Medication: Blood pressure	0.5	0.8	1.5	-1.0	-0.6	-0.8	-1.1	-1.1	-1.0	-1.0	-0.4	-1.2	-0.9	-0.6	-1.1	-0.7	-0.5	-1.0	-1.1	-0.6	-1.1	-0.8
Medication: Allopurinol	0.5	0.6	2.7	-0.9	-0.7	-0.0	-1.6	-0.9	-0.8	-0.8	-0.2	-1.1	-0.8	1.4	-0.3	-0.4	0.1	-0.9	-0.6	-0.5	-0.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.0	-0.7	-0.7	-0.5	0.4	-0.6	-0.3	-0.7	-1.4	-0.3	-0.3	-0.8	-1.0	-0.8	-0.5	-0.7	-0.4	-1.4	-1.0	-0.6
Whole body fat mass	0.5	2.0	5.0	-1.0	0.0	-1.4	-2.2	-1.5	-1.7	-1.4	0.2	-1.6	-1.4	-0.8	-1.0	-1.2	-1.6	-1.4	-2.1	-1.1	-1.2	-2.0
Pulse rate, automated reading	0.5	1.5	4.2	-1.2	-1.4	-1.2	0.1	-1.0	-0.5	-1.2	-1.9	-0.1	-1.1	-0.5	-2.1	-1.4	-0.8	-1.0	-0.8	-1.4	-1.5	-1.7
Chest pain or discomfort	0.5	0.7	3.6	-0.3	0.3	-1.9	-0.2	-0.6	-0.9	-0.3	0.3	-0.1	-0.3	-0.6	0.1	-0.9	-1.9	-0.7	-0.9	-1.1	-0.7	-1.1
Knee pain experienced in last month	0.5	0.8	4.0	-1.0	-1.5	-0.1	-2.0	-0.7	-1.0	-0.9	0.0	-1.2	-1.0	0.1	-0.8	-0.5	-0.1	-0.9	-0.5	0.3	-0.9	0.4
Illnesses of siblings: Diabetes	0.5	0.6	2.9	-0.3	-0.5	0.4	-1.0	-0.3	-0.8	-0.4	1.7	-0.9	-0.7	0.5	0.5	-0.1	1.2	-0.4	-0.5	0.9	0.5	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	2.5	-1.3	-1.6	-0.2	-1.2	-1.1	-1.3	-1.3	1.1	-1.3	-1.3	-0.3	0.1	-0.8	-1.0	-1.1	-0.6	-0.4	-0.4	0.7
Ever had bowel cancer screening	0.5	0.6	2.3	-0.7	-0.9	-0.3	0.8	-0.4	0.4	-0.7	-1.5	0.5	-0.7	-0.7	-1.1	-1.0	-0.3	-0.4	0.1	-1.3	-0.6	-0.5
Friendships satisfaction	0.5	0.6	1.6	0.7	0.3	-1.3	1.1	1.0	0.9	0.9	-0.8	1.1	0.7	0.8	0.6	0.9	0.2	1.0	0.8	-0.5	-0.3	0.1
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.8	-1.2	-1.2	-0.4	-1.3	-1.1	-1.2	-1.1	0.5	-0.4	-1.0	1.2	0.5	-0.3	-0.0	-1.2	-0.7	0.1	-0.6	0.9
Wears glasses or contact lenses	0.5	0.6	1.7	0.3	-0.3	1.1	0.4	0.7	1.3	0.3	-0.8	1.3	0.1	0.5	-0.7	0.2	1.2	0.7	1.2	0.4	0.5	0.5
High cholesterol (Self-reported)	0.5	0.9	2.0	-1.2	-1.4	-0.3	-1.2	-1.1	-1.1	-1.1	-0.1	-1.4	-1.4	0.1	-0.7	-0.7	0.5	-1.1	-1.0	-0.3	-0.6	0.1
Illnesses of father: High blood pressure	0.5	0.6	2.5	-0.5	-0.5	0.7	0.5	-0.5	-0.2	-0.6	-1.0	-0.4	-0.7	-0.8	-1.6	-1.4	-0.2	-0.6	-0.6	-0.7	-0.7	-0.7
Average weekly beer plus cider intake	0.5	0.7	2.8	0.4	0.6	1.7	-0.7	0.3	-0.3	0.2	1.2	-0.6	0.2	0.2	1.4	0.8	1.2	0.2	0.2	1.0	0.9	1.4
Irritability	0.5	0.8	3.4	-0.6	-0.5	-1.8	0.0	-0.7	-0.7	-0.8	-0.4	-0.2	-1.5	-0.3	-0.6	-0.8	-0.5	-0.8	-1.3	-0.7	-1.5	-1.1
Schizophrenia (2018)	0.4	0.8	2.1	-0.9	-0.7	0.0	-0.5	-1.1	-1.4	-0.9	-0.3	-1.1	-0.8	-1.2	-1.1	-1.0	-0.7	-1.1	-1.1	-0.3	-0.9	-0.3
Major Depression (MDD)	0.4	0.5	1.5	-0.4	-0.1	0.3	1.0	-0.6	0.2	-0.6	-0.9	-0.3	-0.7	-0.7	-1.1	-1.2	-0.2	-0.5	-0.6	-0.2	-0.1	-1.0
Reaction Time	0.4	0.8	2.1	0.8	1.0	-0.7	0.3	0.9	1.2	0.8	-1.3	1.4	1.2	1.3	0.1	1.2	0.4	1.0	1.1	-0.2	-0.3	-0.1
Hand grip strength (left)	0.4	1.0	3.2	-0.8	-0.3	-0.9	0.0	-1.1	-1.2	-0.9	1.3	-1.8	-0.8	-1.1	1.1	-0.6	-1.4	-1.0	-1.4	0.0	-0.1	-0.5
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.6	-0.2	-0.3	-0.2	-1.6	-0.2	-0.8	-0.4	1.5	-0.8	-0.4	0.9	1.1	-0.0	-0.8	-0.1	-0.5	0.0	-0.2	0.4
Ever had hysterectomy (womb removed)	0.4	0.5	3.0	0.1	-0.0	-0.0	0.5	0.3	0.3	-0.1	0.4	0.4	-0.0	1.4	0.3	0.4	1.5	0.3	0.5	0.7	0.6	1.7
Trunk fat percentage	0.4	1.4	4.3	-0.9	-0.0	-1.3	-2.1	-1.2	-1.3	-1.1	-0.4	-1.1	-1.0	-0.2	-1.1	-0.9	-1.5	-1.1	-1.5	-1.0	-1.2	-1.8
Maternal smoking around birth	0.4	0.6	2.8	-0.0	0.8	-0.0	0.5	-0.6	-0.2	-0.1	-1.0	-0.3	-0.1	-0.9	-0.7	-0.9	-1.1	-0.5	-0.9	-1.1	-0.7	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.1	0.8	0.8	1.0	0.9	0.8	1.1	0.7	-0.0	1.1	0.9	0.3	-0.1	-0.2	0.7	0.7	0.8	-0.0	0.8	-0.0
Serious illness, injury or assault to yourself	0.4	0.5	2.8	0.8	1.1	-0.3	0.8	0.6	0.3	0.8	0.6	0.4	0.7	1.7	0.8	0.6	-0.3	0.4	0.1	0.1	0.3	-0.1
Had menopause	0.4	0.4	1.3	-0.3	0.3	0.7	-0.8	-0.8	-0.3	-0.8	0.3	-1.0	-1.1	-0.1	-0.7	-1.0	0.4	-0.8	-1.1	-0.1	0.1	-0.4
Allergy	0.4	0.8	2.1	0.8	0.5	1.4	0.1	0.9	0.8	0.8	0.9	0.1	0.7	1.3	0.9	0.9	1.0	0.9	0.9	0.7	1.1	1.4
Neuroticism score	0.4	0.8	3.5	0.7	0.1	0.4	1.9	0.8	1.2	0.8	-1.4	1.4	0.3	-0.4	-1.0	-0.5	0.0	0.6	0.6	-0.6	-0.1	-1.0
Length of working week for main job	0.4	0.4	1.7	-0.7	-0.4	0.7	0.9	-0.7	-0.0	-0.7	-0.4	-0.1	-0.6	-1.3	-1.0	-0.9	-0.6	-0.8	-0.4	-0.3	-0.4	-0.3
Medication: Amlodipine	0.4	0.6	2.2	-0.6	-0.8	-0.6	-0.3	-0.5	-0.3	-0.8	-0.5	-0.6	-0.8	-1.3	-1.5	-1.1	-0.1	-0.5	-0.3	-1.0	-0.6	-0.7
High blood pressure (siblings)	0.4	0.5	3.8	-0.1	-0.6	1.9	-0.1	0.1	0.2	0.1	0.4	0.3	0.2	1.0	-0.1	0.0	0.8	0.1	0.6	0.9	0.8	1.4
Leg fat percentage (right)	0.4	1.6	5.9	1.8	2.4	0.9	-0.0	1.5	1.1	1.6	0.8	1.0	1.4	1.4	0.4	1.5	0.5	1.5	0.9	1.1	1.2	-0.7
Comparative body size at age 10	0.4	1.1	4.0	-0.9	-0.9	-1.1	-1.1	-1.0	-0.8	-1.0	-0.5	-0.1	-1.1	-2.0	-1.2	-1.4	-0.9	-1.0	-1.1	-0.9	-1.1	-1.0
Age at first live birth	0.4	0.7	1.9	-0.8	-0.9	-0.3	-1.3	-0.8	-1.2	-0.6	1.3	-0.7	-0.5	-1.3	0.6	-0.6	-1.4	-0.8	-0.7	-0.4	-0.1	0.3
Eye problems/disorders: None of the above	0.4	0.5	1.7	0.7	1.2	-0.9	-0.1	0.4	0.3	0.5	0.8	0.4	1.3	-0.5	1.1	0.3	-0.4	0.5	0.3	-0.4	1.2	-0.4
Family relationship satisfaction	0.4	0.5	2.4	0.6	0.0	0.1	1.6	0.9	0.9	0.8	-0.7	1.0	0.5	0.2	0.1	0.4	0.7	0.7	0.8	-0.5	0.0	-0.1
Medication: Aspirin	0.4	0.5	1.0	-0.8	-0.9	-1.0	-0.8	-0.7	-1.0	-0.5	-0.1	-0.9	-0.9	0.3	-0.5	-0.5	-0.8	-0.6	-0.4	-0.6	-0.6	-0.5
Loneliness, isolation	0.4	0.5	2.5	-0.7	-0.8	0.9	0.5	-0.7	-0.3	-0.6	-0.1	-0.3	-0.7	-0.5	-0.8	-1.6	-0.7	-0.8	-0.7	-0.6	-0.5	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.0	-0.3	-0.2	-1.1	0.4	-0.3	0.3	-0.2	-1.4	0.0	-0.1	-0.7	-0.6	-0.4	0.1	-0.2	-0.1	-1.2	-0.4	-1.0
Osteoporosis (self-reported)	0.4	0.5	1.7	-0.7	-0.9	-0.5	-1.0	-0.5	-0.9	-0.5	1.3	-1.0	-0.6	-0.7	0.8	-0.1	-0.4	-0.6	-0.3	0.4	0.2	1.2
Miserableness	0.4	0.6	2.2	-0.2	0.0	-0.5	1.3	-0.4	0.2	-0.3	-1.4	0.4	-0.5	-0.1	-1.3	-0.9	-0.4	-0.4	-0.7	-1.1	-0.9	-1.5
Ever taken oral contraceptive pill	0.4	0.5	1.3	-0.7	-1.0	-1.1	-0.2	-0.4	-0.6	-0.4	0.1	-0.5	-0.4	-0.9	-0.6	-1.0	-0.9	-0.5	-0.3	-1.0	-0.3	-0.7
Age started oral contraceptive pill	0.4	0.4	1.3	-0.6	-1.1	0.5	0.2	-0.5	-0.3	-0.6	-0.8	-0.4	-1.2	0.5	-1.0	-0.5	1.1	-0.6	-0.5	0.0	-0.6	0.0
Ever depressed for a whole week	0.4	0.5	1.9	-0.0	-0.1	-0.1	1.0	0.0	0.6	-0.0	-1.4	0.8	-0.2	-1.1	-1.4	-0.8	-0.7	0.1	0.3	-0.7	-0.5	-0.8
Impedance of whole body	0.4	1.9	5.3	0.5	-0.7	1.8	1.6	1.1	1.4	1.1	-0.8	1.4	1.2	1.9	0.6	1.3	1.6	1.1	2.3	0.9	1.1	2.3
Neuroticism (Nagel 2018)	0.3	0.6	3.1	0.2	-0.2	-0.1	1.7	0.2	0.7	0.2	-1.5	0.8	-0.5	-0.8	-1.1	-0.9	0.4	0.1	0.1	-0.6	-0.6	-1.2
Breast Cancer	0.3	0.8	1.9	0.9	0.8	-0.7	-0.1	1.1	0.5	1.0	0.5	1.0	1.3	0.8	1.3	1.4	-0.1	1.2	1.1	0.5	0.6	0.6
Mean Putamen Volume	0.3	0.4	1.5	0.6	0.9	-1.0	-0.0	0.4	0.2	0.6	0.0	0.6	0.5	-0.3	0.3	0.5	-0.8	0.4	-0.1	-0.6	-0.4	-1.2
HDL Cholesterol	0.3	0.6	1.6	0.5	-0.0	1.2	1.3	0.8	1.1	0.7	-0.4	0.8	0.7	0.7	-0.2	0.7	0.3	0.8	1.1	0.4	0.7	0.2
Blood White Count	0.3	2.2	23.4	0.7	0.6	4.8	1.0	0.8	0.6	0.7	0.9	-1.7	-0.1	1.9	1.2	1.0	0.4	0.8	0.9	1.6	0.8	1.0
Waist Hip Ratio (WHR)	0.3	1.3	5.0	1.1	1.0	0.5	-0.4	1.0	-0.0	1.1	2.0	0.4	0.9	0.7	2.2	1.6	0.8	1.0	0.4	1.9	1.2	1.0
Frequency of depressed mood in last 2 weeks	0.3	0.4	3.5	0.1	0.3	0.5	1.9	0.0	0.5	-0.0	-1.0	0.7	0.0	-0.3	-0.9	-0.7	-0.7	-0.1	0.3	-0.5	0.2	-0.6
Hearing difficulty/problems: Yes	0.3	0.4	1.6	0.5	0.1	1.0	0.4	0.7	0.9	0.6	-0.5	0.8	0.1	1.2	-0.0	0.2	1.3	0.5	0.7	0.3	0.1	0.4
Angina	0.3	0.3	2.7	0.2	0.1	-0.5	-1.1	0.4	-0.5	0.2	1.0	-0.1	-0.1	1.6	0.5	0.3	0.5	0.5	0.2	0.1	-0.2	0.4
Vitamin and mineral supplements	0.3	0.3	1.9	0.7	1.4	0.5	0.0	0.3	0.5	0.5	-0.7	0.2	0.5	0.1	-0.4	0.4	0.7	0.4	-0.1	0.1	-0.0	-1.3
Medication: Co-codamol	0.3	0.3	1.0	0.5	0.6	1.0	-0.4	0.5	0.7	0.4	-0.1	0.2	0.8	0.8	-0.1	0.5	0.5	0.6	0.9	0.2	0.7	0.3
Average weekly fortified wine intake	0.3	0.3	3.0	0.3	0.2	-0.5	1.7	0.2	0.6	0.0	-0.7	0.4	-0.4	1.1	-0.3	0.0	0.5	0.2	0.0	-0.2	0.0	0.0
Stomach or abdominal pain in last month	0.3	0.3	1.7	0.1	-0.7	1.2	0.5	0.3	0.5	0.1	0.6	-0.2	0.1	0.5	0.1	-0.2	1.3	0.2	0.5	0.6	0.6	0.8
Body mass index (BMI)	0.3	1.3	6.6	-0.1	1.2	-1.1	-1.6	-0.8	-1.0	-0.6	0.3	-1.0	-0.7	-0.8	-0.9	-0.7	-1.5	-0.7	-1.7	-0.6	-0.8	-2.6
Had other major operations	0.3	0.4	1.5	-0.5	-0.6	0.4	-0.6	-0.5	-0.6	-0.6	1.2	-1.1	-0.7	0.3	0.6	-0.7	-0.2	-0.5	-0.6	0.2	0.2	0.8
Number of live births	0.3	0.5	2.3	0.7	0.8	1.5	0.4	0.4	1.0	0.6	-0.1	0.4	1.0	0.5	-0.6	-0.2	0.2	0.4	0.4	0.6	1.1	-0.7
Mouth/teeth dental problems: Dentures	0.3	0.6	2.7	0.0	0.1	-1.1	0.0	0.0	0.5	-0.0	-1.7	1.1	-0.3	-0.2	-1.2	-0.4	-0.0	0.1	-0.2	-0.9	-0.9	-1.3
Blood clot in the leg (DVT)	0.3	0.4	2.7	0.5	1.1	1.6	-0.6	0.2	0.4	0.5	-0.0	0.4	0.4	0.6	0.5	0.6	0.1	0.3	0.1	1.2	0.3	0.0
Health satisfaction	0.3	0.4	1.1	0.3	-0.6	0.4	0.8	0.8	0.4	0.4	0.5	0.6	0.1	0.6	0.5	0.6	0.5	0.6	0.9	0.6	0.4	1.1
Shortness of breath walking on level ground	0.3	0.3	0.8	-0.3	-0.6	-0.1	-0.8	-0.2	-0.6	-0.4	0.9	-0.4	-0.8	0.8	0.6	-0.1	0.2	-0.3	-0.4	0.6	0.2	0.8
Emphysema/chronic bronchitis	0.3	0.4	2.2	-0.2	-0.0	-1.2	-1.5	-0.4	-0.8	-0.5	0.2	-0.3	-0.6	-0.4	-0.0	-0.2	-0.9	-0.3	-0.6	-0.2	-0.3	-0.1
Medication: Omeprazole	0.3	0.4	2.2	-0.0	-0.3	1.5	0.1	0.2	-0.1	-0.2	0.9	-0.0	-0.0	0.6	0.5	0.3	0.9	0.2	0.6	1.1	0.8	1.1
Medication: Seretide 50 evohaler	0.3	0.4	1.5	1.0	1.1	-0.0	0.8	0.7	0.8	0.5	-0.2	0.6	-0.0	-0.0	-0.4	-0.2	0.7	0.5	-0.2	-0.5	-0.2	-1.2
Number of full sisters	0.3	0.4	1.4	0.7	1.0	-0.5	1.2	0.5	0.5	0.7	-0.7	0.3	0.7	0.5	-0.3	0.3	0.0	0.5	0.2	-0.4	0.3	-0.8
Supplements: Vitamin C	0.3	0.3	1.2	0.3	-0.0	0.3	-0.6	0.4	0.1	0.4	0.9	0.1	0.6	0.1	1.1	0.4	0.9	0.4	0.4	0.9	0.6	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.6	0.3	0.2	-0.9	0.0	0.4	-0.1	0.3	0.6	-0.3	-0.3	0.1	0.9	1.0	0.6	0.4	0.1	0.9	-0.2	1.3
Medication: Aspirin	0.3	0.4	1.2	-0.7	-0.8	-1.1	-1.0	-0.6	-0.8	-0.5	-0.0	-0.8	-0.7	0.4	-0.3	-0.4	-0.6	-0.5	-0.4	-0.4	-0.6	-0.4
Mother’s age at death	0.3	0.3	1.0	-0.6	-0.6	0.8	-0.8	-0.5	-0.1	-0.7	-0.0	-0.3	-0.5	0.3	-0.4	0.1	0.7	-0.6	-0.4	0.9	-0.2	1.0
Leg fat percentage (left)	0.3	1.2	5.5	1.7	2.4	0.6	-0.1	1.3	1.0	1.4	0.3	1.0	1.2	0.9	-0.0	1.1	0.2	1.3	0.5	0.5	0.9	-1.3
Risk taking	0.3	0.4	1.5	0.2	1.0	0.1	-0.5	-0.2	-0.6	-0.1	1.0	-0.7	-0.0	1.1	0.7	0.5	-0.1	-0.2	-0.8	1.2	-0.1	0.3
Diastolic blood pressure, automated reading	0.3	1.0	2.7	1.2	0.9	1.6	0.3	1.3	1.1	1.2	0.5	0.5	1.1	0.4	0.4	1.0	1.4	1.2	1.1	0.4	1.4	0.6
Supplements: Calcium	0.3	0.4	2.3	0.1	0.0	-1.2	1.2	0.1	0.5	-0.0	-1.5	0.3	0.2	-0.4	-0.9	-0.4	0.1	-0.1	-0.1	-0.3	-0.1	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.0	0.6	1.3	1.4	-0.2	0.3	0.5	0.5	-0.2	0.5	0.5	0.7	0.4	0.6	-0.1	0.4	0.3	1.0	0.3	-0.3
Alzheimer’s Disease (in mother)	0.2	0.3	0.9	0.3	0.7	-0.2	-0.9	-0.1	-0.5	0.3	0.1	-0.6	0.2	0.7	-0.2	0.5	-0.1	-0.1	-0.6	0.5	-0.3	-1.0
Crohns Disease (2017)	0.2	0.4	1.5	-0.5	-0.1	0.2	-1.1	-0.6	-0.5	-0.6	0.6	-1.1	-0.7	-0.7	-0.2	-0.8	-1.2	-0.5	-0.6	-0.1	-0.2	-0.8
Irritable Bowel Disease (IBD)	0.2	0.5	1.3	-0.8	-1.0	-0.0	-0.8	-0.7	-0.5	-0.9	0.1	-1.1	-1.1	-0.8	-0.6	-0.6	-0.9	-0.6	-0.3	-0.2	-0.3	0.2
Ulcerative Colitis (UC)	0.2	0.4	2.2	-0.8	-1.5	0.1	-0.7	-0.3	-0.4	-0.6	0.2	-0.8	-1.0	-0.6	-0.3	0.1	0.1	-0.2	0.2	0.4	-0.1	1.4
HbA1C	0.2	0.2	1.3	0.3	-0.1	0.7	0.3	0.5	0.4	0.7	0.0	0.2	0.4	0.1	0.4	0.6	0.7	0.4	0.4	0.2	0.1	1.1
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.7	-0.2	0.2	-1.2	-0.3	-0.3	-0.1	-0.2	0.3	0.2	-0.1	-0.2	0.7	-0.3	-1.3	-0.1	-0.5	-0.5	-0.5	-0.5
Blood Platelet Count	0.2	1.8	8.4	1.0	1.2	-0.3	2.4	0.6	1.5	0.0	-1.9	1.1	0.0	0.7	-2.9	-1.2	1.6	0.5	-0.2	-0.2	-0.3	-2.1
Systolic Blood Pressure	0.2	0.9	5.5	0.1	-0.6	1.6	-0.6	0.5	0.0	-0.0	1.8	-0.7	0.2	0.6	1.0	0.5	1.3	0.4	0.6	0.6	0.9	2.3
Lung FEV1/FVC ratio	0.2	1.0	3.3	-0.9	-0.8	-1.3	-1.7	-0.9	-1.7	-0.5	0.8	-1.8	-1.1	0.5	0.4	0.4	-0.4	-0.9	-1.0	0.1	-0.8	0.7
Lung FVC	0.2	1.3	5.6	0.3	0.0	0.5	0.0	0.5	0.0	0.3	2.2	0.2	0.5	0.8	2.1	1.2	0.7	0.5	0.7	1.7	1.3	2.4
Chronotype (morning person)	0.2	0.5	2.6	-0.4	-0.4	0.2	-1.0	-0.5	-0.1	-0.5	-1.1	-0.2	0.1	-0.5	-1.6	-1.0	0.1	-0.6	-0.3	-1.2	-0.5	-0.9
Supplements: Zinc	0.2	0.2	1.1	0.3	0.1	-0.1	0.1	0.5	0.5	0.2	0.1	1.0	0.7	0.5	0.2	0.2	0.5	0.4	0.6	0.1	0.3	0.3
Diabetes (father)	0.2	0.2	1.2	-0.5	-0.5	-0.1	-0.4	-0.4	-0.4	-0.5	0.8	-0.2	-0.1	0.1	0.3	-0.1	-0.9	-0.4	0.1	-0.1	0.0	1.1
Current tobacco smoking	0.2	0.3	0.8	0.3	0.1	-0.9	0.4	0.3	-0.2	0.2	0.6	-0.6	-0.7	-0.5	0.8	-0.3	-0.5	0.2	-0.5	-0.1	-0.5	-0.8
Fed-up feelings	0.2	0.3	0.9	-0.3	-0.8	-0.1	0.5	-0.2	-0.4	-0.1	-0.0	0.1	-0.8	-0.7	-0.4	-0.9	-0.7	-0.4	-0.5	-0.7	-0.8	-0.8
High blood pressure (mother)	0.2	0.2	0.8	0.6	0.6	0.8	0.1	0.6	0.9	0.4	0.1	0.3	0.5	-0.4	0.2	-0.0	0.3	0.7	0.7	0.3	0.3	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.0	0.4	0.3	0.3	0.6	0.5	0.8	0.4	0.1	0.8	0.4	1.0	0.1	0.1	0.7	0.5	0.6	0.5	0.3	0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.8	0.2	0.1	-0.2	0.8	0.2	0.2	0.4	-0.4	0.5	0.2	-1.4	0.1	-0.3	-0.5	0.2	0.2	-0.4	0.0	-0.7
Heart attack	0.2	0.3	1.0	-0.0	-0.5	-1.0	0.9	0.2	0.0	0.1	-0.7	-0.5	-0.4	0.1	-0.5	-0.5	0.3	0.1	-0.2	-0.7	-0.6	-0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.2	-0.7	-1.1	0.1	0.1	-0.2	0.0	-0.4	-0.7	0.7	-0.2	-0.6	-0.3	0.2	-0.1	-0.1	0.9	-0.2	-0.1	0.9
Medication: Ramipril	0.2	0.2	1.4	0.4	0.5	0.1	0.3	0.4	0.5	0.3	0.0	0.4	0.2	1.2	0.2	0.7	-0.0	0.5	0.5	0.6	0.1	0.7
Illnesses of siblings	0.2	0.3	2.1	0.4	0.7	-1.4	0.5	0.3	0.1	0.3	0.2	0.1	0.4	-0.3	0.7	0.4	-0.9	0.3	-0.1	-0.3	-0.2	-0.8
Impedance of arm (right)	0.2	0.8	2.2	0.0	-0.7	0.5	1.3	0.5	0.9	0.5	-1.2	1.0	0.8	1.4	0.2	0.8	1.1	0.5	1.5	0.5	0.4	1.4
Arm fat percentage (right)	0.2	0.7	4.4	0.2	1.3	-1.1	-1.1	-0.4	-0.6	-0.1	-0.0	-0.3	-0.1	0.1	-0.6	-0.1	-1.1	-0.3	-1.0	-0.4	-0.4	-2.1
Alcohol intake versus 10 years previously	0.2	0.3	1.2	0.2	-0.2	0.6	0.8	0.3	0.5	0.4	-0.7	1.1	0.6	-0.2	-0.9	-0.3	0.7	0.2	0.5	-0.4	0.2	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.4	-0.1	-0.2	-1.1	1.2	0.2	0.4	-0.2	-0.9	0.7	0.2	0.8	-0.5	-0.4	-0.3	0.2	0.3	-0.9	-0.3	-0.3
Pulse rate	0.2	0.3	0.6	0.5	0.8	-0.5	-0.0	0.5	0.2	0.4	0.7	0.6	0.6	0.6	0.8	0.6	-0.8	0.6	0.2	0.2	0.3	-0.4
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.5	-0.3	-0.1	-1.2	-0.1	-0.2	0.2	-0.3	-1.2	-0.0	-0.3	-0.6	-0.1	-0.1	-0.5	-0.2	-0.1	-0.8	-0.7	-0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.1	-0.1	-0.4	0.4	-0.1	-0.2	0.0	-0.2	-0.2	-0.4	-0.6	-0.5	-0.7	-1.0	-0.5	-0.3	-0.5	-0.4	-0.4	-0.7
Medication: Paracetamol	0.2	0.4	1.3	-0.5	-0.1	-0.1	-0.1	-0.6	-0.1	-0.5	-0.5	0.2	-0.3	-1.0	-1.1	-0.8	-0.8	-0.6	-0.2	-1.1	-0.0	-0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.6	0.7	0.2	0.9	1.3	0.8	0.9	0.8	-0.2	0.6	0.5	-0.1	0.1	0.4	0.4	0.6	0.5	0.0	0.5	0.3
Glaucoma (self-reported)	0.2	0.2	1.0	-0.0	-0.2	0.3	0.4	0.2	0.4	-0.0	-0.5	0.5	0.0	1.0	-0.3	0.4	0.6	0.2	0.7	0.6	0.2	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	2.3	0.3	0.2	-1.5	0.6	0.3	0.1	0.3	-0.2	0.3	-0.0	-0.6	0.1	-0.3	-0.5	0.3	-0.2	-0.1	-0.3	-0.7
Wheeze or whistling in the chest in last year	0.2	0.4	1.7	0.0	0.3	-1.1	0.3	-0.2	-0.3	-0.2	-0.3	-0.1	-0.3	-0.1	-0.5	-0.6	-0.7	-0.1	-0.6	-1.1	-0.8	-1.3
Angina (self-reported)	0.2	0.3	2.2	0.4	0.1	-0.3	-0.8	0.6	-0.3	0.4	1.0	0.0	0.0	1.5	0.5	0.4	0.6	0.6	0.4	0.3	-0.1	0.4
Medication: Ibuprofen	0.2	0.2	1.4	-0.1	0.0	0.1	-1.2	-0.1	-0.4	-0.2	0.7	-0.1	-0.0	0.4	0.3	0.5	-0.5	-0.0	-0.2	0.3	0.2	0.5
Mean time to correctly identify matches	0.2	0.4	1.4	0.3	0.5	-0.5	-0.4	0.4	0.6	0.3	-1.0	0.9	0.6	1.2	0.1	0.9	0.1	0.6	0.7	-0.2	-0.5	0.1
Heart disease (mother)	0.2	0.2	0.9	-0.5	-0.9	0.6	0.3	-0.3	-0.1	-0.2	-0.7	-0.2	-0.5	0.0	-1.0	-0.3	0.4	-0.3	0.2	-0.2	-0.3	-0.2
Leg fat mass (right)	0.2	0.7	3.0	-0.0	0.9	-0.6	-1.7	-0.5	-0.8	-0.4	0.9	-1.0	-0.6	-0.1	-0.4	-0.3	-0.9	-0.4	-1.2	-0.2	-0.3	-1.6
Overall health rating	0.2	0.5	2.1	-0.3	-0.0	-0.6	-0.2	-0.4	-0.7	-0.5	-0.2	-0.7	-0.8	-0.5	-1.1	-0.9	-0.9	-0.5	-0.8	-0.7	-0.8	-1.4
Leg pain on walking	0.2	0.2	1.5	0.0	-0.2	1.1	-0.0	0.3	0.1	-0.0	0.4	-0.0	-0.2	-0.1	-0.2	0.2	-0.2	0.2	0.6	0.8	0.5	1.2
Arm fat percentage (left)	0.2	0.8	4.5	-0.0	1.1	-1.3	-1.4	-0.6	-0.8	-0.4	0.1	-0.5	-0.4	-0.2	-0.7	-0.4	-1.4	-0.5	-1.2	-0.6	-0.5	-2.1
Average weekly red wine intake	0.2	0.3	1.2	-0.4	0.1	-0.2	0.6	-0.8	0.2	-0.5	-1.1	-0.2	-0.7	0.2	-1.1	-0.6	0.2	-0.8	-0.8	0.3	-0.4	-0.4
Guilty feelings	0.2	0.3	1.2	0.3	-0.2	-0.2	1.1	0.4	0.8	0.2	-1.1	0.3	0.1	-0.4	-0.6	-0.5	0.1	0.2	0.2	-0.7	-0.1	-0.5
Hearing aid user	0.2	0.2	1.0	0.2	0.3	0.1	0.6	0.1	0.4	0.1	-0.9	0.5	-0.1	1.0	-0.7	-0.3	-0.2	0.0	0.1	-0.6	-0.1	-0.7
Eye problems/disorders: Glaucoma	0.2	0.2	0.5	-0.5	-0.7	-0.1	0.5	-0.3	-0.0	-0.6	-0.7	0.1	-0.6	0.6	-0.7	-0.4	0.0	-0.3	-0.0	0.1	-0.4	-0.3
Medication: Atorvastatin	0.2	0.3	0.9	-0.7	-0.9	-0.2	-0.4	-0.4	-0.6	-0.6	-0.1	-0.3	-0.6	0.4	-0.3	-0.2	-0.4	-0.4	0.4	-0.4	-0.1	0.9
Unable to work because of sickness or disability	0.2	0.2	0.7	0.5	0.8	-0.6	0.2	0.5	0.3	0.6	0.2	0.8	0.4	0.6	0.5	0.5	0.4	0.4	0.2	-0.2	0.4	-0.0
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.0	-0.0	-0.5	-1.0	1.0	0.2	-0.0	0.0	-0.6	-0.4	-0.4	0.2	-0.5	-0.5	0.1	0.1	-0.1	-0.6	-0.6	-0.6
Leg fat mass (left)	0.2	0.9	3.7	-0.2	0.8	-0.9	-1.8	-0.6	-1.0	-0.6	0.7	-1.0	-0.8	-0.3	-0.6	-0.6	-1.1	-0.6	-1.5	-0.5	-0.6	-1.9
Depressed Affect (Nagel 2018)	0.1	0.2	1.9	0.2	-0.3	0.7	1.4	0.2	0.4	0.2	-0.3	0.8	-0.4	-0.3	-0.6	-0.7	0.4	0.1	0.1	-0.1	0.0	-0.2
Alzheimer’s Disease (including proxy)	0.1	0.2	0.7	0.2	0.3	0.5	-0.8	0.1	-0.5	0.2	0.5	-0.8	0.2	0.5	0.0	0.5	0.2	-0.0	-0.4	0.8	-0.2	-0.3
Age at First Birth	0.1	0.2	1.0	-0.1	-0.2	0.6	0.7	-0.2	-0.1	0.3	-0.6	0.1	0.2	-1.0	0.2	0.4	-0.6	-0.1	0.1	0.1	-0.4	-0.3
LDL Cholesterol	0.1	0.2	1.3	0.6	1.1	0.7	-0.0	0.1	0.1	0.2	0.2	-0.6	-0.3	0.7	-0.0	-0.0	0.2	0.1	-0.6	0.3	0.2	0.0
Schizophrenia (2014)	0.1	0.1	0.6	0.1	0.2	0.8	0.2	-0.0	-0.5	0.2	0.1	-0.1	0.6	-0.3	-0.0	0.2	0.1	-0.0	0.1	0.5	0.4	0.6
Triglycerides	0.1	0.2	1.0	0.2	0.8	0.2	-0.6	-0.2	-0.4	0.1	0.5	-0.5	-0.0	-1.0	0.1	-0.2	-0.6	-0.0	-0.5	0.1	0.1	-0.5
Blood Red Count	0.1	1.4	5.3	0.9	0.8	-1.1	-1.1	0.8	-0.4	1.1	2.3	0.3	0.5	1.5	2.2	1.8	-1.1	0.8	0.1	1.1	0.8	1.0
Smoking Status	0.1	0.3	1.5	0.6	0.4	-0.1	0.1	0.6	0.1	0.8	0.8	-0.3	0.1	-0.1	1.2	0.4	-0.4	0.6	0.3	0.3	0.3	-0.0
Allergy or Eczema	0.1	0.2	0.7	0.3	0.4	-0.4	0.1	0.3	0.0	0.3	0.5	0.5	0.3	-0.3	0.5	0.7	0.5	0.2	0.2	0.9	0.5	0.3
Neuroticism	0.1	0.3	2.0	0.4	-0.2	0.6	1.4	0.6	0.6	0.5	0.1	1.1	-0.1	-0.0	0.1	-0.1	0.5	0.5	0.6	0.3	0.3	0.5
Tanning	0.1	0.8	3.8	0.5	0.9	-0.4	1.8	0.3	1.1	0.4	-2.0	0.7	0.4	-1.0	-1.2	-0.1	0.8	0.4	0.6	-0.2	0.1	-0.8
Systolic blood pressure, automated reading	0.1	0.4	2.1	-0.1	-0.2	1.4	-0.7	0.0	0.0	-0.3	0.5	-0.7	-0.2	0.1	-0.3	0.1	1.3	0.0	0.2	0.1	0.5	1.2
Age when periods started (menarche)	0.1	0.3	1.8	-0.3	-0.5	0.6	0.6	-0.2	0.3	-0.3	-1.3	0.3	-0.1	-0.2	-0.7	-0.9	-0.1	-0.1	0.3	-0.5	-0.4	-0.4
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	-0.1	-0.5	0.4	0.2	0.1	-0.1	-0.0	0.5	0.4	0.2	-0.3	0.3	0.4	0.8	0.1	0.5	0.9	0.4	0.7
Medication: Atenolol	0.1	0.1	0.9	0.0	-0.1	-0.3	0.1	0.1	0.1	0.2	-0.2	0.1	0.2	-0.8	-0.9	-0.2	0.0	0.1	0.1	-0.3	-0.1	-0.3
Falls in the last year	0.1	0.1	0.5	0.1	0.1	0.4	0.0	0.1	0.1	0.1	-0.3	-0.2	-0.6	0.5	-0.5	-0.4	0.1	-0.2	-0.5	-0.1	-0.6	-0.7
Hair/balding pattern: Pattern 3	0.1	0.2	0.8	-0.3	-0.2	-0.7	0.9	-0.3	0.1	-0.3	-0.3	0.6	0.0	0.6	-0.2	-0.5	-0.7	-0.2	-0.0	-0.6	-0.0	-0.1
Noisy workplace	0.1	0.2	1.1	0.1	0.1	0.9	-0.2	0.1	0.2	0.3	-1.0	0.2	-0.1	0.0	-0.0	0.5	0.5	0.1	0.4	-0.1	0.1	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	0.2	0.7	0.1	0.1	-0.2	-0.0	0.1	0.7	0.4	-0.1	-0.4	0.2	-0.2	0.2	-0.2	-0.3	0.3	0.6	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.5	-0.2	-0.1	0.5	-0.7	-0.2	-0.3	-0.3	0.7	-0.2	-0.1	0.3	-0.1	0.2	-0.4	-0.2	-0.0	0.4	0.4	0.5
Illnesses of mother	0.1	0.1	0.6	-0.3	-0.2	0.1	0.3	-0.2	-0.2	-0.3	0.1	0.1	-0.3	-0.1	0.5	0.1	0.0	-0.2	-0.1	-0.1	0.2	0.8
Impedance of arm (left)	0.1	0.5	2.3	-0.7	-1.5	0.1	0.7	-0.2	0.2	-0.2	-1.1	0.6	0.1	0.9	-0.1	0.2	0.5	-0.1	1.0	-0.0	0.0	1.5
Exposure to tobacco smoke at home	0.1	0.1	1.1	0.1	-0.1	0.5	0.4	0.1	0.2	0.0	-0.6	-0.2	-0.0	0.1	-1.0	-0.0	0.5	0.1	0.3	-0.5	-0.1	-0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.0	0.2	0.2	0.3	0.2	0.2	0.6	0.3	0.2	0.4	0.4	0.9	0.4	0.2	1.0	0.2	0.5	0.3	0.6	0.8
Body fat percentage	0.1	0.5	3.2	0.1	0.9	-0.6	-1.3	-0.3	-0.4	-0.1	-0.3	-0.3	-0.2	0.2	-0.8	-0.2	-0.8	-0.2	-0.8	-0.6	-0.4	-1.8
Medication for pain relief, constipation, heartburn	0.1	0.1	0.7	0.5	0.4	0.1	0.8	0.3	0.4	0.2	-0.0	0.1	0.3	-0.2	0.4	-0.1	0.7	0.2	-0.3	0.4	-0.2	-0.3
Alcohol intake frequency.	0.1	0.2	1.1	0.4	0.1	0.1	-0.1	0.4	0.5	0.3	-0.2	0.5	0.5	0.2	-0.2	-0.3	1.0	0.3	0.1	-0.4	0.0	-0.4
Mineral and other dietary supplements	0.1	0.2	0.8	0.3	0.2	0.4	0.2	0.4	0.7	0.5	-0.4	0.6	0.9	0.1	0.0	0.5	0.2	0.5	0.7	-0.0	0.1	-0.3
Osteoarthritis (self-reported)	0.1	0.1	0.7	-0.2	-0.2	-0.3	0.0	-0.1	0.2	-0.3	-0.8	-0.0	0.1	0.7	-0.4	0.3	0.3	-0.1	0.2	-0.6	0.1	0.6
Smoking status: Current	0.1	0.2	0.8	0.3	0.2	-0.8	0.4	0.3	-0.1	0.2	0.4	-0.6	-0.6	-0.5	0.7	-0.3	-0.2	0.2	-0.6	-0.0	-0.6	-0.9
Medication: Bendroflumethiazide	0.1	0.1	0.7	-0.2	-0.2	-0.5	0.4	-0.2	-0.1	-0.4	-0.1	-0.3	-0.5	-0.8	-0.8	-0.4	-0.1	-0.1	-0.3	-0.0	-0.4	-0.2
Commuting to job workplace: Cycle	0.1	0.1	0.6	-0.3	-0.5	-0.8	-0.5	-0.1	-0.3	-0.1	-0.2	0.4	-0.3	-0.4	0.1	0.2	-0.0	-0.2	-0.0	0.2	-0.8	0.0
Myopia	0.1	0.2	0.7	0.2	0.5	-0.2	-0.7	0.2	-0.0	0.0	0.1	0.8	0.6	-0.5	0.2	-0.4	-0.7	0.2	0.4	-0.7	0.1	-0.5
Heart disease (siblings)	0.1	0.2	0.5	-0.3	-0.5	0.2	-0.6	-0.3	-0.3	-0.4	-0.3	-0.6	-0.4	0.5	-0.4	-0.4	0.7	-0.4	-0.4	-0.1	-0.5	0.4
Hair Pigment	0.0	0.8	2.8	-0.3	0.1	1.6	-1.0	-0.5	-0.4	-0.1	1.7	-1.2	0.2	1.2	1.2	0.6	-0.5	-0.4	-0.1	0.9	0.3	1.6
Past tobacco smoking	0.0	0.1	0.3	-0.2	-0.4	-0.5	0.4	-0.1	0.2	-0.4	-0.2	-0.0	0.2	-0.2	-0.2	-0.1	-0.1	-0.1	0.1	-0.4	-0.2	0.1
Smoking status: Previous	0.0	0.1	0.3	-0.1	-0.2	0.4	-0.5	-0.0	-0.3	0.2	0.3	-0.0	-0.1	0.4	-0.0	0.1	0.2	-0.0	0.2	0.5	0.3	0.3
Ever smoked	0.0	0.0	0.2	0.2	0.4	-0.3	0.1	0.0	-0.2	0.3	0.2	-0.1	-0.3	-0.2	0.1	-0.1	-0.1	-0.0	-0.3	0.2	0.1	-0.4

Hub : Genes

TBCE

Models

Trait associations