TWAS hub - FAM100B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0424	0.0201	1.8e-08	0.012	0.042	0.038	NA	0.034	1.0e-03	5.2e-09	2.2e-08	NA	1.1e-07
2	TCGA	Glioblastoma Multiforme	0.1640	0.0850	3.5e-04	0.162	0.086	0.071	NA	0.124	1.3e-05	1.4e-03	3.5e-03	NA	1.3e-04
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.0370	0.0184	7.8e-05	0.045	0.030	0.032	NA	0.035	8.0e-06	2.5e-04	1.4e-04	NA	7.2e-05
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0493	0.0278	1.6e-05	0.065	0.054	0.057	NA	0.059	7.4e-08	9.5e-07	5.5e-07	NA	3.5e-07
5	TCGA	Brain Lower Grade Glioma	0.0691	0.0306	1.2e-08	0.073	0.084	0.073	NA	0.068	1.0e-08	9.5e-10	1.2e-08	NA	3.4e-08
6	TCGA	Lung Adenocarcinoma	0.0208	0.0125	3.9e-03	0.003	0.011	0.007	NA	0.013	1.1e-01	1.7e-02	4.1e-02	NA	9.6e-03
7	TCGA	Prostate Adenocarcinoma	0.0879	0.0383	8.1e-09	0.023	0.073	0.062	NA	0.053	1.8e-03	4.5e-08	4.8e-07	NA	2.9e-06
8	TCGA	Soft Tissue Sarcoma	0.0450	0.0270	3.7e-03	0.033	0.027	0.016	NA	0.029	4.6e-03	9.7e-03	3.7e-02	NA	7.4e-03
9	TCGA	Thyroid Carcinoma	0.2520	0.0980	6.8e-14	0.106	0.159	0.167	NA	0.146	1.9e-10	2.8e-15	5.1e-16	NA	4.1e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Depression (self-reported)	4.3	5.1	5.9	-2.2	-2.2	-2.4	-2.4	-2.1	-2.1	-2.2	-2.4	-2.4
Other serious medical condition/disability diagnosed by doctor	4.2	5.4	7.8	-2.4	-1.8	-2.3	-2.3	-2.0	-2.2	-2.6	-2.3	-2.8
Medication: Seretide 50 evohaler	4.1	4.8	7.8	-2.1	-1.6	-2.8	-2.5	-1.2	-2.4	-1.9	-2.5	-2.3
Pulse rate, automated reading	4.0	12.9	20.2	4.5	3.7	2.8	3.2	3.7	3.4	4.1	3.2	3.6
Seen doctor (GP) for nerves, anxiety, tension or depression	3.8	5.8	8.3	-2.2	-1.8	-2.9	-2.4	-2.9	-1.8	-2.5	-2.6	-2.3
Pack years adult smoking proportion	3.4	5.2	8.5	2.9	2.0	1.9	2.1	1.8	2.2	2.8	2.1	2.4
Osteoporosis (self-reported)	3.4	4.2	6.2	-2.2	-1.3	-1.8	-1.9	-2.5	-1.7	-2.4	-2.0	-2.2
Alcohol drinker status: Previous	3.4	3.9	5.4	2.1	2.0	2.2	2.3	0.8	2.3	1.6	2.3	1.7
Number of treatments/medications taken	3.2	5.8	9.6	-2.5	-1.9	-2.3	-2.4	-3.1	-2.3	-2.6	-2.3	-2.1
Exposure to tobacco smoke outside home	3.2	4.2	8.0	2.1	0.9	2.0	1.9	1.6	2.3	2.4	1.8	2.8
Waist Hip Ratio (WHR)	3.1	13.8	38.4	6.2	3.4	0.7	0.9	4.1	1.3	5.5	0.9	4.9
Eye problems/disorders: Diabetes related eye disease	2.9	3.2	5.5	-1.2	-0.9	-2.2	-2.2	-1.4	-2.4	-1.4	-2.1	-1.6
Medication: Allopurinol	2.9	3.9	5.7	2.0	1.5	2.2	2.4	1.1	2.4	1.3	2.4	1.9
Medication: Lisinopril	2.8	3.6	4.8	2.1	2.2	1.8	1.9	1.6	1.7	2.0	1.9	2.0
Pack years of smoking	2.8	4.1	7.3	2.7	1.9	1.6	1.7	1.5	1.8	2.5	1.9	2.2
Ulcerative Colitis (UC)	2.7	5.1	6.7	2.6	2.6	2.5	2.3	1.7	1.9	1.8	2.6	2.1
Ever had bowel cancer screening	2.7	3.2	5.1	-1.0	-0.7	-2.2	-2.2	-1.9	-1.8	-1.8	-2.2	-1.6
Respiratory disease	2.6	5.7	8.3	-1.6	-1.1	-2.9	-2.7	-2.5	-2.1	-2.7	-2.7	-2.5
Taking other prescription medications	2.5	3.8	4.7	-2.1	-1.3	-2.0	-1.9	-2.2	-1.9	-2.1	-1.9	-2.1
Medication: Atorvastatin	2.5	3.1	3.7	-1.8	-1.8	-1.7	-1.7	-1.7	-1.8	-1.9	-1.7	-1.8
Supplements: Calcium	2.5	2.7	8.6	-1.9	-1.6	-1.3	-1.0	-2.9	-0.6	-2.0	-1.0	-1.3
Vitamin and mineral supplements	2.4	3.3	7.0	1.9	0.4	1.6	1.4	2.5	1.0	2.6	1.5	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.1	6.1	-2.0	-1.6	-1.3	-1.3	-2.5	-1.0	-2.1	-1.5	-2.1
Mineral and other dietary supplements	2.4	3.3	8.4	1.9	1.2	1.0	1.2	2.9	0.7	2.5	1.4	2.3
Commuting to job workplace: Public transport	2.4	2.9	6.2	1.4	1.1	1.6	2.1	0.5	2.5	1.6	1.8	1.9
Bilateral oophorectomy (both ovaries removed)	2.3	2.7	3.8	1.5	1.8	1.1	1.5	1.9	1.5	1.9	1.6	1.9
Irritability	2.3	3.8	7.0	-2.6	-2.6	-1.9	-1.9	-1.6	-1.5	-1.5	-2.0	-1.5
Irritable Bowel Disease (IBD)	2.2	5.2	9.0	1.9	2.4	3.0	2.8	1.4	2.2	1.4	3.0	1.8
Medication: Ibuprofen	2.2	2.7	3.2	-1.6	-1.3	-1.4	-1.7	-1.8	-1.8	-1.8	-1.6	-1.6
Bipolar Disorder (2011)	2.1	2.1	3.8	1.7	0.4	1.5	1.2	1.2	1.4	2.0	1.1	1.8
High blood pressure (mother)	2.1	2.9	3.8	1.6	1.7	2.0	1.9	1.1	1.9	1.4	1.8	1.9
Pulse wave Arterial Stiffness index	2.1	2.4	5.5	2.3	2.2	0.7	0.9	1.7	1.2	1.7	0.9	1.3
Angina	2.0	2.6	4.2	-2.0	-1.9	-1.8	-1.5	-1.3	-1.4	-1.4	-1.5	-1.5
Blood White Count	1.9	14.3	26.3	-3.2	-1.9	-3.5	-4.1	-2.9	-3.9	-4.4	-4.0	-5.1
Cardiovascular Disease	1.9	6.2	8.9	3.0	2.3	2.1	2.1	2.6	2.2	3.0	2.1	2.8
Falls in the last year	1.9	2.6	4.4	-1.0	-0.8	-2.1	-2.1	-1.1	-1.8	-1.2	-2.1	-1.6
Pulse wave peak to peak time	1.9	2.3	5.4	-2.3	-2.2	-0.6	-0.9	-1.7	-1.0	-1.6	-0.9	-1.2
Angina (self-reported)	1.8	2.4	4.2	-2.0	-1.9	-1.7	-1.4	-1.3	-1.3	-1.3	-1.4	-1.4
Basal cell carcinoma (self-reported)	1.8	2.1	3.6	-1.8	-1.9	-1.2	-1.2	-1.4	-1.1	-1.9	-1.2	-1.0
Average weekly spirits intake	1.7	2.1	2.9	-1.3	-0.8	-1.6	-1.7	-1.4	-1.3	-1.6	-1.7	-1.5
Hearing difficulty/problems: Yes	1.7	2.6	5.6	-1.0	-0.7	-2.4	-2.0	-1.0	-1.4	-1.6	-2.1	-1.5
Asthma	1.7	3.3	5.9	-1.3	-0.4	-2.1	-1.7	-2.0	-1.6	-2.4	-1.6	-2.4
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	4.6	-1.2	-2.1	-1.9	-1.7	-0.4	-1.5	-0.5	-1.8	-1.2
Diabetes (father)	1.6	2.0	4.3	-0.8	-0.6	-2.0	-2.0	0.3	-2.1	-0.6	-1.8	-1.2
Pulse rate	1.6	2.7	4.6	2.1	1.6	1.0	1.4	1.6	1.5	2.1	1.4	1.9
Had major operations	1.6	1.8	4.2	1.5	1.2	1.4	0.9	2.0	0.4	1.8	1.1	0.8
Asthma (self-reported)	1.6	3.3	6.5	-1.4	-0.4	-2.0	-1.5	-2.3	-1.4	-2.5	-1.5	-2.3
Hearing difficulty/problems with background noise	1.5	2.4	4.1	-1.4	-0.9	-2.0	-1.8	-1.1	-1.6	-1.4	-1.8	-1.5
Gout (self-reported)	1.5	2.0	3.1	1.6	1.6	1.4	1.6	0.7	1.5	0.8	1.8	1.4
Number of full brothers	1.5	1.9	2.9	-1.1	-1.0	-1.0	-1.6	-1.3	-1.7	-1.7	-1.6	-1.4
Illnesses of father: None of the above (group 1)	1.5	1.8	5.2	-2.0	-0.7	0.3	-0.0	-2.1	-0.7	-2.3	0.3	-1.4
Rheumatoid Arthritis	1.4	1.9	3.6	-1.4	-1.3	-1.9	-1.5	-0.7	-1.3	-1.2	-1.6	-1.2
Hand grip strength (right)	1.4	3.8	10.0	2.5	1.6	1.2	1.2	3.2	1.0	2.5	1.3	1.9
Had menopause	1.4	1.7	3.4	1.5	1.7	0.7	1.1	0.8	1.7	1.0	0.9	1.9
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	2.7	-1.0	-1.0	-1.4	-1.6	-1.1	-1.6	-1.4	-1.5	-1.2
Medication: Ventolin 100micrograms inhaler	1.4	1.8	3.1	-1.8	-1.3	-0.5	-0.9	-1.7	-1.1	-1.8	-0.8	-1.6
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.6	5.6	1.6	2.4	1.3	1.0	0.7	1.1	0.3	1.1	0.8
Qualifications: nursing, teaching	1.4	2.2	5.4	-0.3	-0.5	-2.3	-2.1	0.1	-1.8	-0.4	-2.2	-1.1
Major Depression (MDD)	1.3	1.6	3.9	-2.0	-1.5	-0.8	-0.4	-1.5	-0.3	-1.7	-0.6	-1.4
Medication: Metformin	1.3	1.8	2.8	-1.0	-0.6	-1.2	-1.6	-1.5	-1.7	-1.3	-1.6	-1.4
Qualifications: None of the above	1.3	2.9	8.0	-2.6	-2.8	-0.5	-0.9	-1.7	-1.0	-1.5	-1.0	-1.7
Average weekly champagne plus white wine intake	1.3	1.8	2.9	1.7	1.5	1.1	1.3	1.4	1.5	1.2	1.2	1.2
Hearing aid user	1.3	1.5	4.0	-0.5	0.4	-2.0	-1.5	-1.0	-1.2	-1.1	-1.5	-0.8
Schizophrenia (2018)	1.2	2.5	4.6	2.1	1.7	1.7	1.5	1.0	1.7	1.3	1.4	1.7
Crohns Disease (2017)	1.2	2.6	5.2	1.1	1.5	2.3	2.0	1.1	1.5	1.1	2.2	1.2
Neuroticism (2016)	1.2	1.7	5.1	-1.9	-1.2	-1.1	-0.5	-2.2	-0.4	-1.7	-0.6	-0.8
Lung FVC	1.2	5.9	9.8	-1.9	-0.8	-3.1	-3.0	-1.7	-3.0	-1.9	-2.9	-2.4
Neuroticism	1.2	2.8	5.5	-1.6	-0.9	-2.4	-1.7	-2.3	-0.8	-1.7	-2.0	-1.0
Hand grip strength (left)	1.2	3.1	8.5	2.4	1.4	0.8	0.8	2.9	0.4	2.4	0.9	2.0
Wheeze or whistling in the chest in last year	1.2	2.2	2.7	-1.1	-1.3	-1.6	-1.6	-1.6	-1.6	-1.4	-1.6	-1.6
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	3.1	1.3	1.0	1.2	0.6	1.6	0.6	1.8	0.6	1.3
Supplements: Vitamin C	1.2	1.4	2.4	-0.4	-0.0	-1.5	-1.4	-1.3	-0.9	-1.2	-1.5	-1.2
Illnesses of siblings: Diabetes	1.2	1.5	2.7	1.7	1.3	1.3	1.1	0.7	1.3	0.8	1.1	1.4
Commuting to job workplace: Walk	1.2	1.2	3.0	0.2	0.2	-1.4	-1.6	-0.2	-1.7	-0.8	-1.3	-1.1
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	2.8	-1.7	-1.3	-1.3	-0.9	-1.5	-0.4	-0.9	-1.2	-0.9
Eye problems/disorders: Cataract	1.1	1.2	3.2	0.3	1.2	-1.8	-1.4	-0.1	-1.5	-0.3	-1.2	-0.8
Medication: Paracetamol	1.1	1.7	3.4	-1.8	-1.8	-0.8	-0.7	-1.8	-0.3	-1.3	-1.0	-1.3
Schizophrenia (2014)	1.0	2.1	3.6	1.9	1.5	1.7	1.4	0.6	1.5	1.1	1.4	1.6
Ulcerative Colitis	1.0	1.5	2.6	1.4	1.4	1.5	1.4	0.9	0.9	0.4	1.6	0.8
Hypothyroidism (self reported)	1.0	2.3	4.8	-2.0	-1.9	-0.7	-0.7	-2.0	-0.5	-2.2	-0.9	-1.5
Relative age voice broke	1.0	1.6	5.3	-1.2	-0.1	-0.4	-0.7	-1.7	-0.8	-2.3	-0.5	-1.8
Age when periods started (menarche)	1.0	2.5	3.3	-1.8	-1.7	-1.1	-1.6	-1.2	-1.6	-1.8	-1.6	-1.8
Nervous feelings	1.0	1.9	3.3	-1.8	-1.2	-1.3	-0.9	-1.6	-0.6	-1.8	-1.1	-1.6
Fluid intelligence score	1.0	2.1	4.2	-0.5	0.0	-1.9	-1.8	-0.8	-2.1	-1.4	-1.6	-1.4
Father’s age at death	1.0	1.3	3.2	0.8	1.8	1.3	1.4	0.1	1.4	0.2	1.4	0.7
Suffer from ‘nerves’	1.0	1.5	3.2	-1.4	-1.8	-1.4	-1.3	-0.8	-0.9	-0.9	-1.6	-0.6
Breast cancer (self-reported)	1.0	1.2	2.9	0.6	1.1	0.8	1.5	0.1	1.7	0.8	1.4	1.0
Osteoarthritis (self-reported)	1.0	1.3	2.2	1.5	0.9	1.2	0.9	1.3	0.6	1.1	1.0	1.4
Medication: Gliclazide	1.0	1.2	2.0	-0.8	-0.4	-1.3	-1.2	-1.0	-0.8	-0.9	-1.4	-1.4
Ever taken oral contraceptive pill	1.0	1.2	2.0	-0.4	0.1	-1.3	-1.4	-0.3	-1.4	-1.1	-1.3	-1.4
Financial situation satisfaction	1.0	1.3	2.1	-1.4	-1.2	-1.1	-1.1	-0.8	-1.0	-1.2	-1.1	-1.1
Eye problems/disorders: Glaucoma	1.0	1.2	4.4	1.7	1.5	0.3	0.2	2.1	0.1	1.1	0.4	0.2
Worry (Nagel 2018)	0.9	2.0	3.4	-1.7	-1.4	-1.8	-1.1	-1.9	-0.3	-1.4	-1.4	-0.9
Chronic bronchitis/emphysema (father)	0.9	1.1	2.0	-0.9	-0.6	-1.0	-1.0	-1.3	-0.4	-1.3	-1.1	-1.4
Number of live births	0.9	1.2	3.0	1.5	1.7	0.7	0.8	1.0	0.7	1.1	0.9	1.0
Birth weight	0.9	1.9	3.1	1.5	1.0	1.8	1.4	0.9	1.1	1.5	1.5	1.4
Comparative body size at age 10	0.9	2.4	5.2	2.1	0.8	1.2	0.9	1.8	0.6	2.3	1.1	2.1
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.6	-0.7	-0.6	-1.9	-1.1	-0.9	-0.5	-0.8	-1.3	-0.9
Age at last live birth	0.9	1.3	2.3	-1.3	-1.0	-1.5	-1.1	-0.9	-1.1	-0.8	-1.1	-1.1
Diabetes diagnosed by doctor	0.9	1.4	3.2	-0.6	-0.8	-1.4	-1.7	-1.0	-1.5	-0.4	-1.8	-0.8
Number of self-reported non-cancer illnesses	0.9	1.6	3.7	-1.1	-0.9	-1.4	-1.2	-1.9	-1.1	-1.3	-1.2	-1.1
Cholesterol lowering medication	0.9	1.4	2.0	-1.2	-1.4	-0.3	-1.3	-1.1	-1.3	-1.0	-1.2	-1.2
Depressed Affect (Nagel 2018)	0.8	1.7	4.2	-0.5	-0.6	-1.7	-2.0	-0.4	-1.5	-0.5	-2.1	-0.9
Schizophrenia vs Biploar Disorder	0.8	1.1	2.7	-1.5	-0.7	-0.5	-0.6	-1.6	-0.6	-1.5	-0.7	-0.8
Prostate Cancer	0.8	1.1	2.8	1.2	1.0	1.1	0.7	1.7	0.5	1.1	1.0	0.7
Coronary Artery Disease (CAD)	0.8	0.9	1.9	1.4	0.9	0.3	0.6	1.2	0.7	1.0	0.5	1.4
HDL Cholesterol	0.8	1.4	2.9	-1.0	-0.6	1.3	1.7	-0.9	1.7	-0.5	1.5	0.2
Alcohol intake versus 10 years previously	0.8	1.2	2.0	0.4	-0.9	1.4	1.4	0.3	1.4	0.8	1.2	1.2
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	5.0	-1.6	-0.7	-0.4	-0.3	-2.0	-0.1	-2.2	-0.4	-1.5
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.3	-0.7	-1.1	-0.9	-1.1	-0.7	-1.0	-0.9	-1.1	-1.0
Eye problems/disorders: None of the above	0.8	0.9	1.9	0.2	-0.4	1.2	1.1	0.2	1.4	0.9	0.9	1.4
Medication: Aspirin	0.8	1.0	1.6	0.6	0.9	1.1	1.2	0.5	1.3	0.9	1.2	1.1
Loneliness, isolation	0.8	1.1	2.4	-0.6	-1.5	-1.1	-1.4	-0.5	-1.2	0.2	-1.4	-0.5
Risk taking	0.8	1.2	2.5	-1.0	-1.6	-0.8	-1.2	-0.0	-1.4	-0.9	-1.1	-1.3
Neuroticism (Nagel 2018)	0.7	1.7	3.4	-1.0	-1.0	-1.8	-1.6	-1.2	-0.9	-1.0	-1.8	-0.8
Alzheimer’s Disease (in mother)	0.7	0.8	3.3	0.2	-0.6	-1.8	-1.2	0.4	-0.6	0.4	-1.3	0.0
Ovarian Cancer	0.7	0.9	3.3	-1.4	-0.3	-0.7	0.1	-1.8	0.0	-1.4	0.0	-0.6
Crohns Disease (2012)	0.7	1.2	2.6	0.6	1.1	1.4	1.3	1.0	0.5	0.9	1.6	0.9
Primary Biliary Cirrhosis	0.7	1.1	2.7	1.1	1.0	0.7	0.6	1.7	0.6	1.2	0.7	1.2
Supplements: Zinc	0.7	0.8	3.1	-1.1	-0.6	-0.8	-0.2	-1.8	-0.0	-1.1	-0.3	-0.5
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.5	-0.5	0.3	-1.3	-1.0	-1.6	-1.2	-1.1	-0.9	-0.0
Neuroticism score	0.7	1.4	2.4	-1.1	-0.9	-1.6	-1.3	-1.4	-0.7	-1.1	-1.5	-0.5
Hip circumference	0.7	2.9	8.6	-2.9	-2.4	0.6	0.3	-2.3	0.5	-2.0	0.1	-1.1
Happiness	0.7	0.8	2.0	1.0	0.5	0.8	0.6	1.4	0.6	1.1	0.6	1.1
Medication: Paracetamol	0.7	1.2	2.7	-1.2	-1.6	-0.9	-0.9	-1.1	-0.6	-0.7	-1.1	-1.2
Qualifications: College or University degree	0.7	2.3	3.2	1.6	1.5	0.9	1.7	1.0	1.6	1.4	1.8	1.7
Comparative height size at age 10	0.7	3.9	6.6	1.6	0.8	2.2	2.3	1.1	2.6	2.1	2.1	2.4
Leg pain on walking	0.7	0.9	2.1	0.3	0.6	1.3	1.4	0.3	1.3	0.0	1.5	0.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.7	-0.4	-1.1	-0.3	-0.9	-0.1	-1.1	-0.8	-0.9	-1.3
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.0	-0.9	0.0	-1.0	-0.8	-0.9	-0.6	-1.1	-0.8	-1.4
Diastolic blood pressure, automated reading	0.7	2.1	4.7	2.2	1.3	1.1	0.6	1.9	1.0	1.8	0.5	1.7
Alzheimer’s Disease (including proxy)	0.6	0.9	2.1	0.8	-0.6	-1.1	-0.4	0.7	0.5	1.4	-0.7	1.5
Mean Putamen Volume	0.6	0.7	1.4	-1.2	-1.2	-0.6	-0.8	-0.6	-0.7	-0.7	-0.9	-0.5
Lupus	0.6	0.9	2.4	-0.3	-0.1	-1.0	-1.4	-0.6	-1.5	-0.9	-1.1	-0.8
Severe depression (siblings)	0.6	0.6	1.7	-0.2	0.2	-0.8	-0.6	-1.1	-0.6	-1.3	-0.5	-0.9
Illnesses of siblings	0.6	0.8	1.4	-1.0	-0.8	-1.2	-0.8	-0.7	-0.9	-0.6	-0.8	-1.1
Noisy workplace	0.6	0.7	2.0	1.3	1.3	-0.0	-0.4	1.4	-0.4	0.7	-0.4	0.4
Lung cancer (father)	0.6	0.7	2.2	-0.9	-0.9	-0.8	-0.6	-1.5	-0.3	-1.0	-0.6	-0.1
Breastfed as a baby	0.6	0.8	4.1	-0.9	-1.1	0.0	-0.0	-2.0	0.3	-0.8	-0.2	-0.5
Shortness of breath walking on level ground	0.6	0.7	2.5	-0.8	0.3	0.1	-0.4	-1.5	-0.3	-1.6	-0.4	-0.8
Medication for pain relief, constipation, heartburn	0.6	1.1	2.0	1.3	1.4	1.2	0.9	1.2	0.6	1.0	1.0	0.4
Mood swings	0.6	1.1	2.6	-0.3	-0.5	-1.3	-1.6	-0.4	-1.4	-0.4	-1.6	-0.5
Miserableness	0.6	1.0	2.3	-0.3	0.2	-1.1	-1.4	-1.0	-0.9	-0.7	-1.5	-0.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.0	-0.6	0.3	-0.5	-0.3	-1.4	0.0	-1.4	-0.5	-1.4
Ever depressed for a whole week	0.6	0.7	3.6	-0.6	-0.6	-1.9	-0.8	-0.3	-0.5	0.1	-1.1	-0.5
Bipolar Disorder or Schizophrenia	0.5	1.3	2.8	1.7	1.0	0.9	0.9	0.9	1.3	1.2	0.8	1.2
HbA1C	0.5	0.6	2.5	0.8	1.6	0.8	0.5	0.9	0.3	0.2	0.6	0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.9	1.4	1.3	0.2	0.0	1.1	0.1	0.9	0.1	0.3
Chronotype (morning person)	0.5	1.1	5.8	0.9	-0.1	-0.1	-0.4	2.4	-0.8	1.6	-0.3	-0.1
Relative age of first facial hair	0.5	1.1	3.8	-1.4	-0.4	-0.5	-0.5	-0.9	-0.9	-1.9	-0.3	-1.5
Average weekly fortified wine intake	0.5	0.6	1.8	0.6	1.3	-0.9	-1.0	0.3	-0.8	-0.2	-0.9	0.1
Number of incorrect matches in round	0.5	0.8	2.8	-0.9	-0.9	-0.8	-0.7	-0.2	-0.7	-0.4	-0.7	-1.7
Allergy	0.5	1.2	2.6	1.0	-0.3	1.4	0.8	1.2	0.8	1.6	0.7	1.4
Worrier / anxious feelings	0.5	1.0	3.2	-0.7	-0.3	-1.0	-0.9	-1.8	0.0	-1.2	-1.2	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.7	-1.1	-1.6	-0.3	0.3	-0.7	0.3	-0.7	0.3	-0.3
Prospective memory result	0.5	0.6	2.3	-0.7	-1.5	1.1	0.5	-0.5	0.4	-0.3	0.5	-0.5
Neck or shoulder pain in last month	0.5	0.7	2.2	-0.4	-0.6	1.2	1.4	0.0	0.8	-0.1	1.5	-0.1
Migraine (self-reported)	0.5	0.6	2.0	0.6	0.8	0.3	0.8	-0.9	1.4	-0.2	0.6	0.9
Heart disease (mother)	0.5	0.7	1.7	0.9	0.1	0.5	0.7	0.3	1.2	0.9	0.4	1.3
Alcohol intake frequency.	0.5	1.0	2.8	-0.0	0.2	1.2	1.2	-1.7	1.3	-0.8	1.2	0.1
Hypertension (Self-reported)	0.5	1.3	2.7	1.6	1.2	0.8	0.4	1.7	0.6	1.5	0.4	1.3
Illnesses of father: Heart disease	0.5	0.8	1.5	-0.5	-0.9	-0.9	-1.2	-0.1	-1.1	-0.4	-1.2	-0.7
Average weekly red wine intake	0.5	0.7	1.5	0.7	1.2	0.3	0.8	0.9	0.6	0.8	0.8	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.9	-0.4	-1.4	-0.7	-0.8	-0.7	-0.6	0.0	-0.9	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	5.7	-0.2	-2.4	0.4	-0.1	0.7	-0.2	0.5	-0.3	-0.4
Tinnitus: Yes, now most or all of the time	0.5	0.6	0.8	0.7	0.7	0.7	0.9	0.6	0.9	0.5	0.9	0.9
Allergy or Eczema	0.4	1.1	2.2	-1.2	-0.2	-1.1	-0.7	-1.2	-0.9	-1.5	-0.6	-1.3
Diabetes (mother)	0.4	0.5	1.0	0.8	-0.8	-0.3	-0.8	-0.2	-0.3	0.8	-1.0	0.3
Leg fat-free mass (left)	0.4	2.2	3.8	1.4	0.6	2.0	1.5	1.2	1.5	1.7	1.5	1.6
Maternal smoking around birth	0.4	0.5	1.9	-1.0	-1.4	-0.3	-0.5	-0.4	-0.6	-0.5	-0.6	-0.7
Serious illness, injury or assault to yourself	0.4	0.5	1.3	-0.0	0.8	-0.6	-0.4	-0.6	-0.7	-1.0	-0.1	-1.1
High blood pressure	0.4	1.0	2.1	1.5	1.1	0.8	0.3	1.4	0.4	1.2	0.3	1.2
Hayfever, allergic rhinitis or eczema	0.4	0.9	1.6	-1.0	0.2	-1.3	-0.7	-1.0	-0.8	-1.3	-0.5	-1.1
Multivitamins +/- minerals	0.4	0.5	1.4	-0.8	0.1	-0.6	-0.5	-0.9	-0.4	-1.2	-0.4	-0.9
Sitting height	0.4	2.5	6.8	-2.6	-2.0	-0.8	-0.8	-1.6	-0.8	-1.9	-1.1	-1.8
Leg predicted mass (left)	0.4	2.3	4.0	1.4	0.6	2.0	1.6	1.2	1.5	1.7	1.5	1.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.3	0.5	0.1	1.1	1.0	0.3	1.5	0.5	0.8	0.5
Mouth/teeth dental problems	0.4	0.6	1.4	0.1	1.2	0.7	1.0	-0.4	1.1	-0.1	1.0	0.6
Diabetes (self-reported)	0.4	0.6	1.4	-0.1	-0.5	-0.7	-1.2	-0.6	-1.1	0.1	-1.2	-0.1
Trunk fat-free mass	0.4	2.1	4.0	1.5	0.7	1.6	1.5	0.8	1.4	1.7	1.5	2.0
Hair/balding pattern: Pattern 3	0.4	0.6	2.4	-0.7	-0.1	-0.2	-0.1	-1.5	0.3	-1.4	-0.4	-0.5
Trunk predicted mass	0.4	2.4	4.4	1.5	0.7	1.7	1.6	0.9	1.6	1.8	1.6	2.1
Exposure to tobacco smoke at home	0.4	0.4	1.3	0.9	-0.0	0.5	0.3	1.1	0.5	0.9	0.1	0.7
Tense / ‘highly strung’	0.4	0.6	1.4	-1.1	-1.2	-0.7	-0.5	-1.0	-0.1	-0.6	-0.7	-0.6
Medication: Amlodipine	0.4	0.5	2.3	0.7	0.1	0.6	-0.0	1.1	-0.0	1.5	0.0	0.4
Age at first live birth	0.4	0.8	1.4	-1.0	-0.6	-1.0	-0.9	-0.5	-0.7	-0.8	-1.1	-1.2
Mean time to correctly identify matches	0.4	0.9	1.4	-0.2	-0.8	-1.2	-1.2	-0.9	-1.2	-0.5	-1.2	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.2	0.2	0.9	0.8	0.6	1.1	0.2	0.2	0.8	-0.3
Number of full sisters	0.4	0.4	1.2	-0.4	0.0	-1.1	-0.9	0.3	-1.0	-0.2	-0.8	-0.2
Smoking status: Previous	0.4	0.6	1.2	-1.0	-0.5	-0.3	-0.8	-0.7	-1.1	-1.0	-0.7	-0.4
Whole body fat-free mass	0.4	2.1	3.5	1.5	0.6	1.7	1.4	1.0	1.4	1.7	1.4	1.9
Leg fat-free mass (right)	0.4	2.0	3.5	1.5	0.6	1.9	1.4	1.2	1.3	1.7	1.3	1.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.8	0.6	0.8	0.7	0.7	0.1	0.7	0.6	0.8	0.9
Friendships satisfaction	0.4	0.5	0.9	0.8	0.4	-0.9	-0.8	0.7	-0.2	0.6	-0.9	0.5
Medication: Aspirin	0.4	0.6	1.0	0.3	0.4	1.0	1.0	0.2	1.0	0.5	0.9	0.9
Leg predicted mass (right)	0.4	1.9	3.4	1.4	0.6	1.8	1.3	1.1	1.2	1.7	1.3	1.6
Ever smoked	0.4	0.8	1.7	0.9	1.0	0.2	0.4	1.3	0.5	1.2	0.3	1.2
Depression (Nagel 2018)	0.3	0.4	1.1	-0.2	-0.2	-0.9	-1.0	0.3	-0.9	0.1	-0.9	-0.3
Reaction Time	0.3	0.5	1.0	0.1	-1.0	-0.7	-0.9	-0.3	-1.0	0.3	-0.9	-0.0
Age at First Birth	0.3	0.5	1.3	-0.9	-0.5	-1.1	-0.6	-0.0	-0.2	-0.3	-0.9	-0.6
Triglycerides	0.3	0.5	1.7	1.3	0.7	-0.1	-0.2	0.7	0.1	0.9	-0.4	1.1
Height	0.3	6.4	10.0	1.4	0.8	2.8	3.2	1.8	2.8	2.7	3.1	3.0
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.2	1.1	0.2	0.1	-0.2	0.9	-0.3	1.5	-0.2	1.0
Ever had hysterectomy (womb removed)	0.3	0.3	1.3	0.7	1.1	-0.5	-0.2	-0.4	-0.1	-0.2	-0.0	0.8
Medication for hormone replacement therapy	0.3	0.3	0.9	-0.0	-0.9	0.3	0.6	-0.0	0.9	0.5	0.4	0.3
Townsend deprivation index at recruitment	0.3	0.4	1.9	-0.2	-0.5	0.4	0.4	-1.4	0.8	-0.6	0.2	0.3
Fed-up feelings	0.3	0.5	1.3	1.0	0.9	0.6	-0.1	1.1	0.2	0.7	-0.2	0.8
Qualifications: CSEs or equivalent	0.3	0.4	1.5	-0.8	0.1	0.0	-0.1	-0.9	-0.2	-1.2	-0.1	-0.9
Impedance of leg (left)	0.3	1.2	2.0	-1.4	-0.9	-1.4	-0.9	-1.1	-0.5	-1.3	-1.1	-1.0
Pain all over the body in last month	0.3	0.3	1.1	-1.0	-1.0	0.1	0.1	-0.7	0.1	-0.4	0.1	-0.2
Medication: Simvastatin	0.3	0.4	1.1	0.8	0.9	0.6	0.2	0.2	0.3	0.5	0.2	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.2	0.3	0.6	-0.2	0.5	0.6	1.0	1.1	0.4	0.8
Length of working week for main job	0.3	0.4	0.6	0.6	0.6	-0.7	-0.7	0.7	-0.6	-0.2	-0.6	-0.6
Headache pain in last month	0.3	0.5	1.0	-0.5	-1.0	-0.9	-0.7	-0.6	-0.3	-0.4	-1.0	-0.4
Glaucoma (self-reported)	0.3	0.4	1.6	1.0	0.8	0.2	0.2	1.3	0.0	0.5	0.3	-0.1
Arm fat-free mass (right)	0.3	1.6	2.9	1.5	0.5	1.4	1.2	0.9	1.2	1.5	1.1	1.7
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.9	-0.5	0.4	-0.6	-0.7	-0.8	-0.9	-0.7	-0.5	-0.1
Health satisfaction	0.3	0.4	1.7	-0.9	-0.1	0.3	0.2	-1.3	0.2	-0.9	0.3	0.3
Chest pain or discomfort	0.3	0.4	1.1	-0.5	-0.5	-1.0	-0.6	-0.5	-0.7	-0.4	-0.6	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.3	-0.9	-0.1	-0.6	-0.2	-1.2	-0.0	-0.8	-0.3	0.1
Back pain experienced in last month	0.3	0.4	1.0	-0.2	-0.7	0.6	0.4	-1.0	0.7	-0.7	0.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.4	-1.0	-0.8	-0.4	-0.7	-1.2	-0.5	-0.7	-0.8	-0.5
Whole body water mass	0.3	1.9	3.2	1.4	0.5	1.7	1.4	1.0	1.3	1.7	1.3	1.8
Mother’s age at death	0.3	0.4	1.0	0.4	1.0	-0.1	0.2	1.0	-0.0	0.8	0.4	0.7
Medication: Blood pressure	0.3	0.6	1.4	0.2	0.2	1.2	0.8	1.1	0.2	0.5	1.1	0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.4	2.3	0.9	1.5	-0.0	-0.2	0.7	-0.0	-0.0	-0.0	0.1
Medication: Bendroflumethiazide	0.3	0.5	1.2	-0.0	-0.4	1.1	0.9	-0.2	1.1	0.2	0.9	0.4
Alcohol drinker status: Never	0.3	0.3	0.8	-0.5	-0.9	-0.7	-0.4	-0.8	-0.5	-0.3	-0.3	-0.1
Basal metabolic rate	0.3	1.8	3.3	1.2	0.4	1.8	1.4	0.9	1.4	1.5	1.4	1.7
Arm fat-free mass (left)	0.3	1.7	2.9	1.4	0.5	1.6	1.2	0.9	1.2	1.5	1.1	1.7
Average weekly beer plus cider intake	0.3	0.4	1.5	0.0	-1.2	-0.6	-0.7	-0.5	-0.5	-0.2	-0.9	-0.1
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.0	-1.4	-1.1	-0.5	0.1	-1.2	-0.2	-1.0	0.0	-1.1
Arm predicted mass (left)	0.3	1.7	2.9	1.5	0.5	1.7	1.2	1.0	1.1	1.4	1.2	1.6
Alzheimer’s Disease (in father)	0.2	0.2	0.6	-0.1	-0.3	-0.5	0.2	-0.3	0.8	0.4	-0.1	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.6	-0.2	0.1	-1.0	-0.8	-0.4	-1.3	-0.8	-0.6	-0.6
Body Mass Index (BMI) (2010)	0.2	0.2	0.4	-0.0	0.2	-0.7	-0.6	0.3	-0.5	-0.4	-0.6	-0.6
Fasting Glucose	0.2	0.2	0.4	0.4	0.6	0.6	0.5	0.3	0.6	0.1	0.5	0.2
Blood Eosinophil Count	0.2	1.6	5.7	2.4	2.2	1.0	0.4	1.3	0.2	0.5	0.6	-0.1
Lung FEV1/FVC ratio	0.2	0.9	2.1	0.2	0.4	1.5	1.3	0.2	1.2	0.3	1.3	0.8
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.7	-0.6	0.0	-0.3	-0.5	-0.9	-0.5	-0.8	-0.4	-0.3
Medication: Co-codamol	0.2	0.2	0.8	-0.3	0.8	-0.0	0.2	-0.2	0.4	-0.9	0.2	-0.5
Trunk fat percentage	0.2	0.8	2.1	-1.4	-1.4	0.5	0.2	-1.1	0.5	-1.2	-0.1	-0.5
Current tobacco smoking	0.2	0.3	1.0	0.7	0.0	0.4	0.2	0.8	0.3	1.0	0.3	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.8	0.1	-0.4	-0.0	-0.7	1.3	-1.1	0.6	-0.5	-0.3
Medication: Levothyroxine sodium	0.2	0.3	1.0	-0.5	-0.4	-0.3	-0.1	-1.0	0.2	-0.7	-0.2	-0.5
Waist circumference	0.2	0.6	2.1	0.9	-0.1	0.7	0.4	0.1	0.9	0.9	0.2	1.5
Hair/balding pattern: Pattern 2	0.2	0.2	0.5	0.1	-0.6	-0.7	-0.1	0.6	0.0	0.7	-0.1	-0.1
Had other major operations	0.2	0.2	0.9	-0.5	-1.0	-0.6	-0.1	-0.1	0.0	-0.2	-0.3	-0.2
Financial difficulties in last 2 years	0.2	0.3	1.1	-0.3	0.2	-0.2	0.0	-1.0	-0.2	-1.0	0.1	-0.5
Weight	0.2	0.9	2.6	0.2	-0.3	1.6	1.2	-0.0	1.3	0.4	1.1	1.0
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.1	1.0	0.3	0.2	0.3	0.8	0.3	1.0	0.3	0.9
Medication: Lansoprazole	0.2	0.3	1.0	-0.4	0.2	-0.4	-0.5	-1.0	-0.5	-0.5	-0.3	-0.3
Illnesses of mother	0.2	0.2	0.8	-0.4	0.3	-0.2	-0.5	0.7	-0.9	0.2	-0.3	-0.6
Arm fat mass (right)	0.2	0.6	2.0	-0.2	-0.6	1.4	0.9	-0.1	1.1	0.1	0.8	0.8
Standing height	0.2	1.7	2.8	0.7	0.2	1.2	1.6	0.7	1.7	1.5	1.5	1.6
Peak expiratory flow (PEF)	0.2	0.4	0.6	-0.7	-0.3	-0.8	-0.6	-0.3	-0.7	-0.4	-0.6	-0.7
Pulse wave reflection index	0.2	0.2	0.6	-0.1	-0.3	-0.2	-0.4	0.4	-0.7	-0.1	-0.3	-0.7
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.0	-0.7	-0.2	-1.0	-0.5	-0.2	-0.4	-0.1	-0.4	-0.0
Loud music exposure frequency	0.2	0.2	1.2	-0.4	-0.4	0.3	-0.2	0.6	-1.1	0.3	0.1	-0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.8	-0.3	0.0	0.9	0.8	-0.2	0.6	-0.5	0.8	-0.3
Body fat percentage	0.2	0.7	2.0	-1.3	-1.4	0.5	0.1	-0.9	0.5	-1.0	-0.1	-0.4
Leg fat percentage (right)	0.2	0.6	1.2	-1.1	-0.9	0.5	0.3	-1.1	0.7	-0.9	0.1	-0.0
Worry too long after embarrassment	0.2	0.3	0.8	0.5	0.5	-0.9	-0.4	-0.1	0.0	0.4	-0.6	0.8
Number of children fathered	0.2	0.2	0.7	-0.1	0.1	0.8	0.1	0.7	-0.6	-0.1	0.4	-0.1
Medication: Blood pressure	0.2	0.4	0.8	0.8	0.4	-0.3	-0.6	0.7	-0.4	0.9	-0.5	0.5
Arm predicted mass (right)	0.2	1.2	2.2	1.3	0.4	1.3	1.0	0.7	1.0	1.3	0.9	1.5
Family relationship satisfaction	0.2	0.2	0.4	-0.0	-0.3	-0.6	-0.6	0.5	-0.4	-0.0	-0.7	0.1
Arm fat percentage (left)	0.2	0.6	1.5	-0.9	-1.2	1.1	0.7	-0.6	1.0	-0.5	0.5	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.9	-0.8	-0.3	-0.0	0.0	-0.9	0.2	-0.8	-0.1	-0.4
Smoking status: Current	0.2	0.4	1.2	0.8	0.2	0.4	0.3	1.0	0.3	1.1	0.4	0.2
Arm fat mass (left)	0.2	0.7	2.0	-0.3	-0.9	1.4	0.9	-0.4	1.1	-0.0	0.7	0.7
Wears glasses or contact lenses	0.2	0.3	0.9	-0.4	-0.1	-0.4	-0.5	0.0	-0.6	-0.6	-0.4	-0.9
Illnesses of father: High blood pressure	0.2	0.2	0.7	0.3	-0.2	-0.6	-0.2	0.5	0.3	0.8	-0.4	0.3
Myopia	0.2	0.2	0.7	0.5	0.3	0.1	0.5	-0.6	0.8	-0.3	0.3	0.4
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.5	-0.5	-0.7	-0.7	-0.2	-0.4	-0.3	-0.3	-0.2	-0.0
Impedance of whole body	0.2	1.0	2.9	-1.7	-1.1	-1.0	-0.4	-0.9	-0.1	-1.1	-0.6	-1.0
Bipolar Disorder (2018)	0.1	0.1	0.4	-0.0	-0.5	-0.6	-0.3	0.2	-0.0	0.3	-0.5	-0.2
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.6	0.4	0.8	0.1	-0.1	-0.1	-0.7	-0.7	0.3	0.2
Breast Cancer	0.1	0.2	0.6	0.2	-0.1	0.3	0.3	0.6	-0.0	0.6	0.4	0.8
LDL Cholesterol	0.1	0.1	0.3	-0.1	-0.4	0.4	0.3	0.1	0.6	-0.1	0.3	-0.1
Blood Platelet Count	0.1	0.9	2.8	-1.4	-0.8	-0.6	-0.4	-1.7	0.2	-1.0	-0.6	-0.9
Blood Red Count	0.1	1.0	4.4	2.1	1.6	0.3	0.3	0.3	1.1	0.3	0.1	0.5
BMI	0.1	0.8	2.1	0.3	-0.2	1.3	1.1	-0.4	1.4	0.1	0.9	1.0
Systolic Blood Pressure	0.1	0.4	1.5	0.6	0.3	0.1	-0.5	1.2	-0.7	0.7	-0.2	0.0
Smoking Status	0.1	0.3	0.7	-0.1	-0.5	-0.1	-0.7	0.9	-0.7	0.7	-0.6	-0.1
Tanning	0.1	1.0	3.2	1.2	0.7	1.0	0.4	1.8	0.4	1.5	0.3	0.7
Sensitivity / hurt feelings	0.1	0.2	0.8	-0.2	0.6	-0.5	0.0	-0.9	0.2	-0.4	-0.1	0.5
Systolic blood pressure, automated reading	0.1	0.3	1.0	0.5	1.0	0.2	-0.5	0.3	-0.5	-0.4	-0.4	-0.2
Impedance of leg (right)	0.1	0.7	1.6	-1.2	-0.8	-1.2	-0.4	-0.7	-0.2	-0.9	-0.6	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	0.3	0.0	0.0	-0.2	0.5	-0.1	0.6	-0.1	0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	0.5	0.4	-0.1	-0.2	-0.2	-0.6	0.1	-0.0	0.2
Stomach or abdominal pain in last month	0.1	0.2	0.6	-0.3	-0.1	0.8	0.2	0.3	-0.2	0.1	0.5	-0.5
Supplements: Glucosamine	0.1	0.1	0.3	-0.2	-0.4	-0.1	-0.2	-0.6	0.0	-0.3	-0.3	-0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	1.0	-0.2	-1.0	0.1	0.2	0.3	0.1	0.5	0.2	0.3
Medication: Atenolol	0.1	0.2	0.5	-0.1	-0.3	-0.7	-0.5	0.2	-0.3	-0.2	-0.6	-0.1
Body mass index (BMI)	0.1	0.4	1.4	-0.1	-0.3	1.2	0.6	-0.3	0.8	-0.2	0.6	0.5
Trunk fat mass	0.1	0.6	1.4	-0.9	-1.2	0.9	0.5	-0.7	0.8	-0.6	0.3	0.0
Past tobacco smoking	0.1	0.2	0.4	0.6	0.2	0.5	0.5	0.0	0.7	0.2	0.5	0.1
Alcohol usually taken with meals	0.1	0.2	0.5	-0.7	-0.7	-0.5	-0.1	-0.3	0.2	-0.1	-0.3	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.7	-0.1	-0.6	0.2	-0.3	0.8	-0.5	0.5	-0.2	0.0
Medication: Ramipril	0.1	0.1	0.3	-0.3	-0.3	-0.1	0.0	-0.5	-0.5	-0.2	0.2	0.0
Impedance of arm (right)	0.1	0.6	2.8	-1.7	-0.8	-0.5	-0.0	-0.6	0.1	-0.7	-0.1	-0.8
Arm fat percentage (right)	0.1	0.5	1.2	-0.8	-1.0	1.1	0.6	-0.5	0.8	-0.4	0.4	0.3
Time employed in main current job	0.1	0.1	0.4	0.2	-0.1	0.4	-0.0	0.6	0.1	0.4	-0.1	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.7	-0.8	-0.5	-0.3	-0.2	-0.7	-0.3	-0.3	-0.2	-0.3
Mouth/teeth dental problems: Dentures	0.1	0.2	0.7	-0.1	0.9	0.0	-0.3	-0.5	-0.5	-0.8	-0.2	-0.4
Medication: Cholesterol lowering	0.1	0.2	0.5	-0.1	-0.4	-0.7	-0.6	-0.6	-0.3	-0.2	-0.7	0.1
Impedance of arm (left)	0.1	0.6	2.5	-1.6	-1.0	-0.4	0.2	-0.5	0.5	-0.7	0.1	-0.7
Hair/balding pattern: Pattern 4	0.1	0.3	1.0	0.5	1.0	1.0	0.2	-0.2	-0.1	-0.7	0.3	-0.2
Birth weight of first child	0.1	0.2	0.6	0.3	-0.1	0.6	0.6	0.2	0.8	0.1	0.4	0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.8	0.7	0.9	-0.4	-0.2	0.2	-0.0	0.1	-0.2	-0.2
Forced vital capacity (FVC), Best measure	0.1	0.4	0.7	-0.9	-0.2	-0.9	-0.5	-0.7	-0.4	-0.7	-0.6	-0.6
Emphysema/chronic bronchitis	0.1	0.1	0.5	-0.2	-0.7	0.1	-0.0	-0.5	-0.1	-0.3	-0.1	-0.6
Medication: Omeprazole	0.1	0.1	0.4	-0.1	-0.4	-0.3	0.1	0.3	0.1	0.4	-0.0	0.6
Whole body fat mass	0.1	0.6	1.7	-0.4	-0.9	1.3	0.9	-0.2	1.1	-0.0	0.7	0.6
Leg fat mass (right)	0.1	0.5	1.3	-0.3	-0.5	1.2	0.8	-0.3	1.1	-0.1	0.6	0.6
Overall health rating	0.1	0.2	0.7	-0.3	-0.2	0.2	0.5	-0.6	0.9	-0.4	0.4	0.6
Knee pain experienced in last month	0.1	0.2	0.7	-0.8	0.2	0.2	-0.0	-0.2	-0.2	-0.9	0.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.9	-0.3	-1.0	-0.1	0.1	-0.2	0.3	0.0	-0.1	0.4
Long-standing illness, disability or infirmity	0.1	0.2	0.6	-0.1	0.2	0.0	-0.2	-0.6	-0.0	-0.7	-0.1	-0.6
Medication for cholesterol	0.1	0.1	0.5	0.6	0.7	-0.5	-0.2	0.2	-0.1	-0.0	-0.2	-0.1
Guilty feelings	0.1	0.2	1.1	-0.0	-0.5	0.4	0.3	0.1	0.2	0.5	0.2	1.1
High cholesterol (Self-reported)	0.1	0.1	0.4	-0.3	-0.7	0.3	-0.0	-0.6	0.1	-0.0	-0.1	0.0
Leg fat percentage (left)	0.1	0.5	1.4	-1.0	-0.8	0.5	0.2	-1.2	0.7	-0.9	-0.0	-0.1
Number of operations (self-reported)	0.1	0.2	0.9	0.4	0.3	0.3	0.1	1.0	-0.4	0.4	0.4	-0.0
Fractured/broken bones in last 5 years	0.1	0.2	0.8	-0.4	-0.5	-0.1	-0.2	-0.9	-0.5	-0.3	-0.1	-0.4
Age started oral contraceptive pill	0.1	0.2	0.5	0.4	0.4	-0.3	0.0	0.4	0.3	0.5	-0.1	0.7
Unable to work because of sickness or disability	0.1	0.2	0.6	0.3	0.0	-0.8	-0.6	-0.2	-0.2	0.0	-0.7	-0.0
Commuting to job workplace: Cycle	0.1	0.1	0.8	-0.1	-0.0	0.3	0.4	-0.0	0.1	0.1	0.4	0.9
Pain experienced in last month	0.1	0.2	0.3	0.3	0.5	-0.4	-0.4	0.4	-0.4	0.5	-0.3	0.5
Heart disease (siblings)	0.1	0.2	0.9	-0.3	0.2	-0.0	0.1	-0.5	0.3	-0.9	0.1	0.5
Leg fat mass (left)	0.1	0.4	1.1	-0.3	-0.5	1.0	0.6	-0.4	1.0	-0.2	0.4	0.5
Heel T-Score	0.0	0.3	1.6	-0.7	-1.2	0.1	0.3	0.4	0.4	-0.0	0.2	0.1
Hair Pigment	0.0	0.6	1.2	-1.0	-0.2	-0.6	-0.5	-0.9	-0.4	-1.1	-0.6	-1.1
Frequency of depressed mood in last 2 weeks	0.0	0.1	0.2	-0.3	-0.3	-0.4	-0.1	-0.2	0.1	0.1	-0.1	0.4
Forced vital capacity (FVC)	0.0	0.1	0.5	-0.7	-0.1	-0.4	-0.2	-0.4	-0.2	-0.3	-0.2	-0.3
Heart attack	0.0	0.0	0.1	-0.1	0.3	-0.2	-0.3	-0.0	-0.2	-0.3	-0.2	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.2	0.4	-0.7	-0.5	-0.3	-0.2	-0.6	-0.1	-0.3	-0.3	-0.2
Blood clot in the leg (DVT)	0.0	0.0	0.1	0.1	0.1	-0.1	-0.3	-0.1	-0.3	-0.3	-0.3	-0.1
High blood pressure (siblings)	0.0	0.0	0.1	0.2	0.2	0.2	-0.0	0.1	-0.3	-0.1	0.1	0.2
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.2	0.0	0.4	-0.2	-0.2	-0.2	-0.1	-0.3	-0.2	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.2	0.4	0.3	0.0	-0.1	0.1	-0.1	0.0	-0.1	0.0

Hub : Genes

FAM100B

Models

Trait associations