[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr20:32,594,714-34,795,372

Best TWAS P=3.68e-19 · Best GWAS P=4.08e-22 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EDEM2 0.09 0.09 enet 12 0.09 5.8e-11 -6.90 7.1 1.8e-12 -0.32 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex UQCC 0.07 0.04 lasso 2 0.05 1.4e-06 -8.00 8.9 3.7e-19 -0.88 0.15 0.85 TRUE
3 GTEx Adipose Subcutaneous EDEM2 0.10 0.07 lasso 9 0.07 2.1e-06 -7.00 7.0 3.3e-12 -0.31 0.99 0.00 FALSE
4 GTEx Adipose Subcutaneous TRPC4AP 0.06 0.01 lasso 6 0.01 3.8e-02 4.21 5.2 2.2e-07 -0.37 0.24 0.03 FALSE
5 GTEx Adipose Subcutaneous PROCR 0.13 0.05 enet 4 0.05 8.2e-05 -7.00 7.3 2.2e-13 -0.32 0.93 0.00 TRUE
6 GTEx Adipose Subcutaneous UQCC1 0.09 0.12 lasso 2 0.11 4.5e-09 -7.71 7.9 3.6e-15 -0.90 0.96 0.04 FALSE
7 GTEx Adipose Visceral Omentum UQCC1 0.15 0.08 lasso 7 0.07 1.6e-04 -7.71 7.4 1.7e-13 -0.87 0.48 0.37 FALSE
8 GTEx Adrenal Gland MMP24-AS1 0.18 0.04 enet 10 0.13 2.2e-05 -6.45 6.0 1.5e-09 -0.74 0.22 0.21 FALSE
9 GTEx Artery Aorta EDEM2 0.13 0.08 enet 10 0.07 6.3e-05 -4.41 6.6 3.9e-11 -0.37 0.84 0.06 FALSE
10 GTEx Artery Tibial EDEM2 0.14 0.10 lasso 6 0.08 1.1e-06 -7.00 6.2 6.4e-10 -0.23 1.00 0.00 FALSE
11 GTEx Brain Cerebellar Hemisphere MYH7B 0.18 0.10 lasso 5 0.08 3.7e-03 -4.26 -5.4 7.8e-08 0.26 0.47 0.07 FALSE
12 GTEx Brain Cerebellum GSS 0.19 0.12 enet 15 0.19 2.9e-06 -4.32 -5.5 4.9e-08 0.33 0.28 0.16 FALSE
13 GTEx Brain Frontal Cortex BA9 UQCC1 0.16 0.07 lasso 3 0.08 3.7e-03 -8.00 6.2 5.6e-10 -0.80 0.08 0.38 FALSE
14 GTEx Breast Mammary Tissue UQCC1 0.10 0.06 lasso 8 0.08 5.3e-05 1.40 6.0 2.1e-09 -0.66 0.45 0.30 FALSE
15 GTEx Breast Mammary Tissue (Male) UQCC1 0.06 0.04 lasso 1 0.02 1.4e-01 -7.77 7.8 7.8e-15 -0.90 0.04 0.13 FALSE
16 GTEx Cells EBV-transformed lymphocytes EDEM2 0.15 0.17 lasso 4 0.15 1.3e-05 -6.90 6.9 5.4e-12 -0.27 0.48 0.03 FALSE
17 GTEx Cells EBV-transformed lymphocytes PROCR 0.19 0.05 enet 25 0.09 7.3e-04 -0.76 -5.2 2.4e-07 0.58 0.09 0.23 FALSE
18 GTEx Cells EBV-transformed lymphocytes NCOA6 0.11 0.06 enet 15 0.06 3.9e-03 -4.10 5.4 5.9e-08 -0.31 0.17 0.35 FALSE
19 GTEx Cells Transformed fibroblasts EDEM2 0.08 0.02 lasso 5 0.03 1.8e-03 -4.26 7.8 6.3e-15 -0.67 0.41 0.16 FALSE
20 GTEx Cells Transformed fibroblasts UQCC1 0.23 0.24 lasso 8 0.25 9.4e-19 -7.74 7.6 3.5e-14 -0.88 1.00 0.00 TRUE
21 GTEx Colon Transverse UQCC1 0.11 0.01 lasso 4 0.01 1.0e-01 -8.19 7.5 9.1e-14 -0.48 0.08 0.09 FALSE
22 GTEx Esophagus Mucosa UQCC1 0.13 0.10 enet 10 0.07 1.1e-05 -7.77 8.2 2.8e-16 -0.89 0.45 0.54 FALSE
23 GTEx Esophagus Mucosa CEP250 0.29 0.00 lasso 9 0.00 5.3e-01 -0.61 -5.9 4.7e-09 0.61 0.06 0.27 FALSE
24 GTEx Heart Left Ventricle PROCR 0.10 0.04 enet 8 0.05 1.6e-03 -7.00 6.3 3.5e-10 -0.24 0.26 0.07 FALSE
25 GTEx Lung UQCC1 0.13 0.08 lasso 5 0.06 1.0e-05 -7.71 7.9 2.7e-15 -0.90 0.46 0.54 FALSE
26 GTEx Muscle Skeletal UQCC1 0.10 0.04 enet 19 0.05 1.3e-05 -6.78 7.1 1.0e-12 -0.79 0.64 0.34 FALSE
27 GTEx Muscle Skeletal CEP250 0.09 0.04 lasso 9 0.07 3.6e-07 -3.56 5.3 9.8e-08 -0.79 0.98 0.01 FALSE
28 GTEx Muscle Skeletal ACSS2 0.04 0.04 enet 12 0.04 3.1e-05 -3.46 -5.1 3.1e-07 0.29 0.82 0.02 FALSE
29 GTEx Nerve Tibial MYH7B 0.21 0.12 lasso 8 0.12 9.7e-09 -4.26 -6.2 6.2e-10 0.33 1.00 0.00 FALSE
30 GTEx Nerve Tibial EDEM2 0.21 0.19 enet 29 0.17 4.9e-12 -7.34 6.4 1.9e-10 -0.29 1.00 0.00 FALSE
31 GTEx Nerve Tibial UQCC1 0.07 0.04 enet 6 0.03 2.7e-03 -7.73 7.7 1.6e-14 -0.88 0.23 0.73 FALSE
32 GTEx Nerve Tibial MMP24-AS1 0.32 0.02 enet 49 0.13 1.3e-09 -0.54 -5.4 8.3e-08 0.38 0.04 0.07 FALSE
33 GTEx Pancreas MYH7B 0.24 0.00 enet 17 0.04 1.0e-02 -2.19 -6.4 1.6e-10 0.44 0.08 0.09 FALSE
34 GTEx Pancreas EDEM2 0.20 0.23 lasso 8 0.23 3.5e-10 -7.00 -7.0 3.6e-12 0.36 1.00 0.00 FALSE
35 GTEx Pancreas PROCR 0.40 0.13 lasso 13 0.18 5.4e-08 -6.60 -6.4 1.7e-10 0.32 0.98 0.00 FALSE
36 GTEx Skin Sun Exposed Lower leg UQCC1 0.19 0.13 enet 16 0.10 8.1e-09 -7.73 7.8 8.0e-15 -0.84 1.00 0.00 FALSE
37 GTEx Spleen PROCR 0.35 0.31 lasso 6 0.29 4.8e-08 -7.00 -6.8 7.5e-12 0.30 0.74 0.02 FALSE
38 GTEx Stomach UQCC1 0.09 0.14 lasso 2 0.15 1.9e-07 -7.71 7.5 4.8e-14 -0.86 0.46 0.39 FALSE
39 GTEx Thyroid MYH7B 0.06 0.03 enet 15 0.06 3.6e-05 -3.78 -6.7 2.2e-11 0.40 0.85 0.02 FALSE
40 GTEx Thyroid RP4-614O4.12 0.08 0.08 lasso 5 0.07 6.8e-06 4.27 6.0 2.5e-09 -0.44 0.97 0.00 FALSE
41 METSIM Adipose EDEM2 0.04 0.05 lasso 2 0.04 3.9e-07 -7.00 7.0 2.6e-12 -0.30 1.00 0.00 FALSE
42 METSIM Adipose UQCC1 0.09 0.04 enet 18 0.05 1.5e-07 -7.72 7.8 9.2e-15 -0.90 0.14 0.86 FALSE
43 NTR Blood UQCC 0.01 0.01 enet 6 0.00 1.6e-02 -7.72 7.9 2.9e-15 -0.89 0.08 0.78 FALSE
44 ROSMAP Brain Pre-frontal Cortex EDEM2 0.10 0.08 lasso 5 0.07 2.0e-09 -6.90 6.9 7.1e-12 -0.31 1.00 0.00 FALSE
45 ROSMAP Brain Pre-frontal Cortex UQCC1 0.05 0.05 lasso 5 0.06 1.7e-08 -7.78 7.3 3.0e-13 -0.84 0.21 0.79 FALSE
46 ROSMAP Brain Pre-frontal Cortex GDF5 0.10 0.13 lasso 2 0.12 2.9e-15 -7.74 -7.7 1.0e-14 0.90 0.83 0.17 FALSE
47 YFS Blood EDEM2 0.08 0.09 lasso 4 0.10 1.2e-29 -6.90 7.3 3.5e-13 -0.45 1.00 0.00 FALSE
48 YFS Blood PROCR 0.01 0.00 blup 348 0.01 3.3e-03 -7.65 7.0 1.9e-12 -0.70 0.08 0.75 FALSE
49 YFS Blood UQCC 0.21 0.19 lasso 26 0.20 6.4e-64 -7.71 7.7 1.9e-14 -0.88 1.00 0.00 FALSE
50 The Cancer Genome Atlas Bladder Urothelial Carcinoma UQCC 0.03 0.04 blup 67 0.03 2.6e-03 -7.74 8.2 3.6e-16 -0.91 0.02 0.91 FALSE
51 The Cancer Genome Atlas Breast Invasive Carcinoma EDEM2 0.09 0.03 enet 10 0.05 1.7e-10 -7.34 5.6 2.7e-08 -0.27 0.98 0.02 TRUE
52 The Cancer Genome Atlas Breast Invasive Carcinoma UQCC 0.08 0.11 blup 67 0.12 1.1e-22 -7.77 8.3 1.3e-16 -0.89 1.00 0.00 FALSE
53 The Cancer Genome Atlas Glioblastoma Multiforme UQCC 0.15 0.02 blup 67 0.04 2.0e-02 -2.78 7.0 2.2e-12 -0.74 0.02 0.64 FALSE
54 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CEP250 0.02 0.01 blup 43 0.02 8.0e-04 -3.65 -5.8 6.8e-09 0.79 0.03 0.83 FALSE
55 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma UQCC 0.05 0.06 blup 66 0.06 3.6e-07 -6.47 7.4 1.7e-13 -0.87 0.13 0.87 FALSE
56 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CEP250 0.03 0.01 blup 43 0.03 2.6e-04 -9.67 -5.3 9.2e-08 0.77 0.01 0.89 FALSE
57 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma UQCC 0.09 0.10 blup 67 0.10 7.2e-11 -7.55 8.1 7.7e-16 -0.88 0.97 0.03 FALSE
58 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma UQCC 0.08 0.01 lasso 3 0.01 9.0e-02 -6.78 7.1 1.7e-12 -0.72 0.04 0.85 FALSE
59 The Cancer Genome Atlas Brain Lower Grade Glioma EDEM2 0.07 0.02 blup 102 0.04 2.1e-05 -7.34 7.6 2.7e-14 -0.37 0.42 0.47 TRUE
60 The Cancer Genome Atlas Brain Lower Grade Glioma GDF5 0.09 0.11 blup 76 0.12 1.0e-13 -7.59 -8.2 2.9e-16 0.83 0.14 0.86 TRUE
61 The Cancer Genome Atlas Brain Lower Grade Glioma UQCC 0.04 0.06 lasso 6 0.05 2.3e-06 -7.73 7.7 1.1e-14 -0.90 0.66 0.34 FALSE
62 The Cancer Genome Atlas Lung Adenocarcinoma UQCC 0.10 0.07 enet 10 0.07 1.5e-08 -7.78 7.3 2.3e-13 -0.89 0.09 0.91 FALSE
63 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MMP24 0.04 0.04 blup 62 0.02 7.4e-04 -3.48 5.3 1.4e-07 -0.55 0.48 0.37 FALSE
64 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UQCC 0.07 0.08 blup 67 0.07 1.1e-08 -7.55 6.4 2.0e-10 -0.82 0.05 0.95 FALSE
65 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GDF5 0.05 0.02 blup 76 0.04 1.4e-03 -7.74 -8.4 3.0e-17 0.89 0.03 0.91 FALSE
66 The Cancer Genome Atlas Pancreatic Adenocarcinoma UQCC 0.12 0.03 blup 67 0.09 1.7e-04 -7.55 8.1 5.2e-16 -0.83 0.02 0.89 FALSE
67 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma UQCC 0.22 0.21 lasso 7 0.18 1.9e-07 -7.55 7.9 3.2e-15 -0.84 0.32 0.68 FALSE
68 The Cancer Genome Atlas Prostate Adenocarcinoma FAM83C 0.16 0.10 lasso 4 0.11 2.1e-11 -8.35 7.9 4.1e-15 -0.58 0.00 1.00 FALSE
69 The Cancer Genome Atlas Prostate Adenocarcinoma GDF5 0.05 0.05 lasso 5 0.04 7.2e-05 -9.67 -8.6 8.8e-18 0.95 0.00 1.00 FALSE
70 The Cancer Genome Atlas Prostate Adenocarcinoma UQCC 0.07 0.10 lasso 8 0.11 1.3e-11 -7.58 8.2 3.0e-16 -0.90 0.37 0.63 FALSE
71 The Cancer Genome Atlas Soft Tissue Sarcoma UQCC 0.07 0.06 blup 66 0.07 5.2e-05 -7.73 7.5 5.5e-14 -0.89 0.02 0.97 FALSE
72 The Cancer Genome Atlas Stomach Adenocarcinoma GDF5 0.09 0.04 enet 13 0.05 2.4e-04 -9.67 -7.1 9.1e-13 0.85 0.00 0.99 FALSE
73 The Cancer Genome Atlas Stomach Adenocarcinoma UQCC 0.07 0.06 lasso 10 0.06 2.8e-05 -8.00 7.9 2.0e-15 -0.88 0.04 0.95 FALSE
74 The Cancer Genome Atlas Testicular Germ Cell Tumors PROCR 0.18 0.00 blup 44 0.14 1.7e-05 -6.63 6.4 1.3e-10 -0.38 0.01 0.87 FALSE
75 The Cancer Genome Atlas Thyroid Carcinoma CEP250 0.05 0.03 blup 43 0.04 5.8e-05 -3.66 -5.7 1.3e-08 0.78 0.12 0.83 TRUE
76 The Cancer Genome Atlas Thyroid Carcinoma GDF5 0.02 0.00 blup 76 0.00 1.9e-01 -7.77 -7.6 3.8e-14 0.90 0.02 0.88 FALSE
77 The Cancer Genome Atlas Thyroid Carcinoma UQCC 0.15 0.21 blup 67 0.22 1.2e-20 -7.77 8.2 2.2e-16 -0.88 0.51 0.49 FALSE
78 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma UQCC 0.13 0.15 lasso 1 0.11 7.1e-04 -6.67 6.7 2.5e-11 -0.74 0.04 0.65 FALSE