[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr4:69,713-2,058,475

Best TWAS P=9.76e-23 · Best GWAS P=3.48e-19 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	IDUA	0.05	0.03	lasso	4	0.04	3.7e-05	3.46	-6.8	9.9e-12	0.69	0.02	0.97	FALSE
2	GTEx	Adipose Subcutaneous	IDUA	0.09	0.09	lasso	4	0.07	1.5e-06	-8.95	-8.6	5.4e-18	0.96	0.00	1.00	FALSE
3	GTEx	Adipose Subcutaneous	DGKQ	0.32	0.23	enet	18	0.26	2.3e-21	-8.36	-9.6	9.1e-22	0.92	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	UVSSA	0.30	0.14	enet	44	0.28	1.4e-22	4.72	-6.1	8.5e-10	0.36	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	MAEA	0.14	0.01	enet	19	0.04	5.2e-03	-0.77	5.3	1.2e-07	-0.17	0.23	0.06	FALSE
6	GTEx	Adipose Visceral Omentum	IDUA	0.26	0.08	lasso	8	0.05	8.1e-04	-8.36	-8.1	5.7e-16	0.85	0.05	0.85	FALSE
7	GTEx	Adipose Visceral Omentum	DGKQ	0.29	0.20	enet	18	0.22	1.3e-11	-8.95	-7.1	1.0e-12	0.85	0.00	1.00	FALSE
8	GTEx	Artery Aorta	IDUA	0.22	0.04	enet	17	0.06	5.2e-04	-8.17	-7.1	9.3e-13	0.55	0.02	0.88	FALSE
9	GTEx	Artery Aorta	DGKQ	0.23	0.09	enet	9	0.13	8.9e-08	8.20	-9.4	8.8e-21	0.76	0.00	0.99	FALSE
10	GTEx	Artery Aorta	CTBP1	0.10	0.02	enet	12	0.02	3.0e-02	4.05	6.8	1.0e-11	-0.56	0.25	0.12	FALSE
11	GTEx	Artery Coronary	IDUA	0.29	0.05	enet	17	0.08	1.5e-03	-8.38	-7.2	5.1e-13	0.71	0.03	0.72	TRUE
12	GTEx	Artery Coronary	SLC26A1	0.39	0.20	enet	13	0.23	2.4e-08	8.20	7.7	1.6e-14	-0.85	0.00	0.99	FALSE
13	GTEx	Artery Tibial	MAEA	0.16	0.11	enet	19	0.11	7.9e-09	4.94	6.0	2.0e-09	-0.26	1.00	0.00	FALSE
14	GTEx	Artery Tibial	IDUA	0.15	0.05	enet	24	0.05	7.5e-05	4.52	-8.0	1.0e-15	0.69	0.04	0.95	FALSE
15	GTEx	Artery Tibial	DGKQ	0.17	0.13	enet	16	0.16	8.2e-13	-6.33	-7.9	1.9e-15	0.81	0.08	0.92	TRUE
16	GTEx	Artery Tibial	UVSSA	0.27	0.01	enet	40	0.14	1.9e-11	1.99	-5.2	2.5e-07	0.22	0.87	0.03	FALSE
17	GTEx	Brain Cerebellar Hemisphere	SLC26A1	0.33	0.14	lasso	8	0.15	1.0e-04	4.52	6.9	7.1e-12	-0.77	0.04	0.87	FALSE
18	GTEx	Brain Cerebellum	SLC26A1	0.61	0.41	enet	22	0.46	2.1e-15	4.56	6.0	1.5e-09	-0.69	0.87	0.13	FALSE
19	GTEx	Breast Mammary Tissue	MAEA	0.35	0.07	enet	58	0.24	1.1e-12	4.95	5.4	6.6e-08	-0.18	0.98	0.00	FALSE
20	GTEx	Breast Mammary Tissue	DGKQ	0.32	0.16	lasso	9	0.22	1.3e-11	-8.95	-9.8	9.8e-23	0.92	0.00	1.00	TRUE
21	GTEx	Breast Mammary Tissue	UVSSA	0.23	0.07	enet	30	0.24	1.5e-12	-4.68	-5.5	4.8e-08	0.23	0.87	0.01	FALSE
22	GTEx	Breast Mammary Tissue	CTBP1-AS2	0.19	0.09	lasso	6	0.15	6.1e-08	-5.60	5.3	1.4e-07	-0.19	0.98	0.00	FALSE
23	GTEx	Breast Mammary Tissue (Male)	DGKQ	0.09	0.03	enet	18	0.02	9.5e-02	-8.38	-7.1	9.8e-13	0.73	0.01	0.76	FALSE
24	GTEx	Breast Mammary Tissue (Male)	CRIPAK	0.21	-0.01	enet	17	0.03	7.1e-02	-0.87	-5.1	2.6e-07	0.38	0.07	0.22	FALSE
25	GTEx	Breast Mammary Tissue (Female)	DGKQ	0.36	0.02	enet	31	0.08	2.0e-03	-8.36	-8.8	9.6e-19	0.82	0.00	0.96	FALSE
26	GTEx	Cells EBV-transformed lymphocytes	DGKQ	0.67	0.57	lasso	7	0.57	2.2e-22	-8.38	-8.3	1.0e-16	0.93	0.11	0.89	FALSE
27	GTEx	Cells EBV-transformed lymphocytes	UVSSA	0.28	0.20	lasso	5	0.19	9.4e-07	-4.68	-5.9	3.4e-09	0.22	0.54	0.03	FALSE
28	GTEx	Cells Transformed fibroblasts	IDUA	0.16	0.05	enet	19	0.05	1.2e-04	3.47	-5.8	7.7e-09	0.52	0.24	0.33	FALSE
29	GTEx	Cells Transformed fibroblasts	UVSSA	0.28	0.13	enet	43	0.20	4.8e-15	4.71	-7.1	1.1e-12	0.39	1.00	0.00	FALSE
30	GTEx	Colon Sigmoid	MAEA	0.17	0.10	lasso	5	0.12	4.3e-05	4.83	5.4	6.7e-08	-0.14	0.40	0.03	FALSE
31	GTEx	Colon Sigmoid	UVSSA	0.45	0.00	enet	19	0.22	2.7e-08	0.36	-6.5	8.4e-11	0.35	0.20	0.08	FALSE
32	GTEx	Colon Transverse	MAEA	0.21	0.16	enet	21	0.14	3.5e-07	4.17	8.0	1.0e-15	-0.45	0.74	0.25	FALSE
33	GTEx	Colon Transverse	UVSSA	0.29	0.17	enet	28	0.23	2.1e-11	-4.68	-5.8	7.9e-09	0.21	0.86	0.07	FALSE
34	GTEx	Esophagus Gastroesophageal Junction	MAEA	0.27	0.08	enet	23	0.22	1.5e-08	4.78	6.9	4.6e-12	-0.16	0.38	0.04	TRUE
35	GTEx	Esophagus Gastroesophageal Junction	DGKQ	0.16	0.08	lasso	2	0.10	1.9e-04	6.18	-8.4	3.5e-17	0.53	0.12	0.29	FALSE
36	GTEx	Esophagus Mucosa	DGKQ	0.34	0.11	lasso	14	0.17	1.6e-11	-8.38	-7.4	1.1e-13	0.83	0.01	0.99	FALSE
37	GTEx	Esophagus Mucosa	SLC26A1	0.45	0.39	enet	15	0.40	2.5e-28	4.56	5.3	1.4e-07	-0.67	1.00	0.00	FALSE
38	GTEx	Esophagus Mucosa	UVSSA	0.33	0.23	enet	21	0.28	4.9e-19	-4.68	-5.8	6.7e-09	0.26	1.00	0.00	FALSE
39	GTEx	Esophagus Muscularis	IDUA	0.18	0.10	lasso	4	0.15	2.0e-09	3.52	-6.9	4.6e-12	0.61	0.09	0.91	FALSE
40	GTEx	Esophagus Muscularis	DGKQ	0.15	0.17	lasso	3	0.15	3.6e-09	-8.95	-9.2	3.0e-20	0.99	0.00	1.00	FALSE
41	GTEx	Esophagus Muscularis	UVSSA	0.35	0.03	enet	33	0.16	3.5e-10	-1.58	-5.1	3.0e-07	0.29	0.93	0.01	FALSE
42	GTEx	Heart Left Ventricle	SLC26A1	0.22	0.13	enet	10	0.17	1.4e-09	4.56	5.4	6.0e-08	-0.67	0.15	0.85	FALSE
43	GTEx	Heart Left Ventricle	UVSSA	0.09	0.01	enet	13	0.01	1.0e-01	4.72	-6.9	7.3e-12	0.37	0.10	0.06	FALSE
44	GTEx	Lung	MAEA	0.25	0.18	enet	34	0.21	7.4e-16	4.95	5.5	4.8e-08	-0.23	1.00	0.00	FALSE
45	GTEx	Lung	IDUA	0.14	0.02	lasso	5	0.04	8.9e-04	3.52	-6.1	9.4e-10	0.54	0.11	0.82	FALSE
46	GTEx	Lung	DGKQ	0.36	0.29	lasso	5	0.32	5.6e-25	-8.36	-9.0	2.7e-19	0.96	0.00	1.00	FALSE
47	GTEx	Lung	SLC26A1	0.51	0.41	lasso	9	0.42	1.2e-34	4.52	5.6	2.7e-08	-0.68	1.00	0.00	FALSE
48	GTEx	Lung	UVSSA	0.42	0.12	lasso	15	0.26	3.2e-20	-4.68	-5.5	4.9e-08	0.27	1.00	0.00	FALSE
49	GTEx	Lung	MYL5	0.11	0.00	enet	19	0.00	1.7e-01	-6.33	5.5	3.9e-08	-0.54	0.05	0.12	FALSE
50	GTEx	Muscle Skeletal	DGKQ	0.15	0.07	enet	15	0.09	6.6e-09	4.52	5.2	2.1e-07	-0.60	0.98	0.01	FALSE
51	GTEx	Nerve Tibial	IDUA	0.25	0.12	lasso	5	0.18	9.8e-13	-8.38	-8.3	9.0e-17	0.89	0.02	0.98	FALSE
52	GTEx	Nerve Tibial	DGKQ	0.30	0.17	lasso	4	0.14	3.8e-10	-8.95	-9.6	1.1e-21	0.97	0.00	1.00	FALSE
53	GTEx	Nerve Tibial	UVSSA	0.32	0.14	enet	21	0.30	3.7e-21	-4.68	-5.5	4.1e-08	0.21	1.00	0.00	FALSE
54	GTEx	Ovary	DGKQ	0.32	0.18	lasso	3	0.15	1.8e-04	6.16	-5.5	3.4e-08	0.21	0.16	0.08	FALSE
55	GTEx	Pancreas	IDUA	0.19	0.03	enet	18	0.04	1.1e-02	-8.36	-9.4	5.5e-21	0.81	0.01	0.98	FALSE
56	GTEx	Pancreas	SLC26A1	0.38	0.26	lasso	9	0.28	3.0e-12	4.52	7.0	3.0e-12	-0.71	0.54	0.46	FALSE
57	GTEx	Pituitary	SLC26A1	0.37	0.38	enet	14	0.33	3.9e-09	4.52	6.0	2.0e-09	-0.74	0.11	0.88	FALSE
58	GTEx	Pituitary	UVSSA	0.43	0.07	lasso	7	0.24	9.3e-07	-4.68	-5.5	4.8e-08	0.16	0.64	0.02	FALSE
59	GTEx	Skin Sun Exposed Lower leg	MAEA	0.20	0.04	enet	31	0.09	3.8e-08	4.39	5.9	4.6e-09	-0.20	0.91	0.01	FALSE
60	GTEx	Skin Sun Exposed Lower leg	UVSSA	0.41	0.30	lasso	11	0.38	1.3e-33	-4.68	-5.2	1.9e-07	0.17	1.00	0.00	FALSE
61	GTEx	Skin Sun Exposed Lower leg	CTBP1-AS2	0.16	0.03	lasso	10	0.05	8.8e-05	-3.93	5.2	2.3e-07	-0.17	0.70	0.01	FALSE
62	GTEx	Small Intestine Terminal Ileum	MAEA	0.31	0.02	enet	30	0.08	7.7e-03	4.96	8.1	4.8e-16	-0.41	0.09	0.09	FALSE
63	GTEx	Spleen	MAEA	0.39	0.16	lasso	8	0.24	6.8e-07	4.78	5.3	1.2e-07	-0.14	0.22	0.06	FALSE
64	GTEx	Spleen	DGKQ	0.45	0.33	lasso	4	0.35	8.9e-10	-8.36	-8.9	4.9e-19	0.91	0.00	1.00	FALSE
65	GTEx	Spleen	UVSSA	0.17	0.20	lasso	2	0.16	8.9e-05	-4.85	-5.2	2.5e-07	0.11	0.09	0.42	FALSE
66	GTEx	Stomach	IDUA	0.36	0.17	lasso	5	0.16	5.5e-08	-7.68	-8.2	1.7e-16	0.78	0.01	0.98	FALSE
67	GTEx	Stomach	FGFRL1	0.12	0.01	lasso	7	0.01	6.7e-02	-7.06	-7.7	1.7e-14	0.73	0.07	0.67	FALSE
68	GTEx	Stomach	DGKQ	0.35	0.19	enet	7	0.23	2.6e-11	-8.38	-8.9	4.7e-19	0.88	0.10	0.90	FALSE
69	GTEx	Stomach	SLC26A1	0.26	0.17	enet	14	0.16	4.0e-08	4.56	5.8	8.1e-09	-0.72	0.04	0.96	TRUE
70	GTEx	Stomach	UVSSA	0.38	0.20	enet	48	0.26	5.2e-13	-5.60	-7.5	8.1e-14	0.35	0.99	0.01	FALSE
71	GTEx	Testis	MAEA	0.24	0.19	lasso	2	0.18	3.3e-08	4.94	5.2	1.8e-07	-0.20	0.97	0.00	FALSE
72	GTEx	Thyroid	IDUA	0.15	0.00	enet	14	0.04	8.6e-04	3.43	-5.2	2.2e-07	0.58	0.02	0.88	FALSE
73	GTEx	Thyroid	FGFRL1	0.39	0.05	enet	47	0.14	6.9e-11	-4.02	-6.2	6.8e-10	0.23	0.94	0.04	FALSE
74	GTEx	Thyroid	TMEM175	0.13	0.04	lasso	4	0.05	4.9e-05	3.52	-6.5	8.4e-11	0.62	0.28	0.30	FALSE
75	GTEx	Thyroid	DGKQ	0.43	0.23	lasso	7	0.28	9.9e-22	-8.38	-9.0	1.5e-19	0.91	0.00	1.00	FALSE
76	GTEx	Thyroid	UVSSA	0.51	0.34	enet	38	0.40	3.5e-32	-4.68	-6.0	1.6e-09	0.26	1.00	0.00	FALSE
77	GTEx	Thyroid	CRIPAK	0.51	0.14	enet	44	0.34	6.1e-27	4.39	-6.0	1.6e-09	0.27	1.00	0.00	FALSE
78	GTEx	Vagina	UVSSA	0.33	0.12	lasso	9	0.27	7.8e-07	-2.31	-5.5	4.0e-08	0.38	0.03	0.82	FALSE
79	GTEx	Vagina	CRIPAK	0.42	0.04	enet	36	0.29	1.9e-07	-8.95	-6.8	1.2e-11	0.50	0.02	0.87	FALSE
80	GTEx	Whole Blood	DGKQ	0.37	0.27	enet	18	0.29	5.4e-27	-8.38	-8.7	3.2e-18	0.94	0.08	0.92	FALSE
81	GTEx	Whole Blood	SLC26A1	0.07	0.05	enet	13	0.07	3.0e-07	-8.95	8.1	4.0e-16	-0.91	0.00	1.00	FALSE
82	GTEx	Whole Blood	UVSSA	0.14	0.05	lasso	9	0.07	5.0e-07	-4.68	-5.8	8.3e-09	0.17	0.92	0.01	FALSE
83	GTEx	Whole Blood	PCGF3	0.26	0.12	enet	18	0.23	6.5e-21	-4.21	5.5	3.1e-08	-0.20	1.00	0.00	FALSE
84	GTEx	Whole Blood	RP11-440L14.1	0.17	0.05	lasso	6	0.14	2.6e-13	2.30	5.1	2.9e-07	-0.17	0.99	0.00	FALSE
85	METSIM	Adipose	DGKQ	0.22	0.20	enet	24	0.22	1.5e-31	-8.95	-8.4	4.4e-17	0.94	0.00	1.00	FALSE
86	METSIM	Adipose	IDUA	0.12	0.05	blup	399	0.07	8.5e-11	-7.43	-9.0	2.8e-19	0.56	0.68	0.32	FALSE
87	METSIM	Adipose	SLC26A1	0.16	0.13	enet	10	0.13	2.1e-18	4.56	5.9	3.2e-09	-0.71	1.00	0.00	FALSE
88	NTR	Blood	CTBP1	0.05	0.04	blup	411	0.04	6.6e-14	4.34	6.3	3.3e-10	-0.16	1.00	0.00	FALSE
89	NTR	Blood	DGKQ	0.02	0.01	enet	5	0.01	1.4e-03	-8.36	-8.1	4.4e-16	0.94	0.00	1.00	FALSE
90	ROSMAP	Brain Pre-frontal Cortex	MAEA	0.12	0.10	blup	375	0.10	2.0e-13	4.96	7.0	2.9e-12	-0.36	1.00	0.00	FALSE
91	ROSMAP	Brain Pre-frontal Cortex	DGKQ	0.37	0.36	lasso	6	0.38	1.9e-51	4.56	6.4	1.9e-10	-0.81	1.00	0.00	FALSE
92	ROSMAP	Brain Pre-frontal Cortex	CTBP1	0.06	0.04	bslmm	395	0.03	6.7e-05	4.46	6.4	1.6e-10	-0.37	0.87	0.05	TRUE
93	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DGKQ	0.06	0.02	blup	49	0.05	2.7e-05	-8.36	-7.4	1.4e-13	0.64	0.02	0.84	FALSE
94	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SLC26A1	0.05	0.01	blup	53	0.02	1.2e-02	8.20	6.7	2.1e-11	-0.70	0.07	0.35	FALSE
95	The Cancer Genome Atlas	Breast Invasive Carcinoma	DGKQ	0.03	0.01	blup	49	0.01	6.3e-04	4.82	-6.5	6.6e-11	0.64	0.01	0.72	FALSE
96	The Cancer Genome Atlas	Breast Invasive Carcinoma	IDUA	0.05	0.02	enet	12	0.05	7.7e-11	4.56	-6.5	6.4e-11	0.76	0.03	0.97	FALSE
97	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DGKQ	0.11	0.03	blup	49	0.08	1.4e-04	-7.06	-6.3	2.4e-10	0.80	0.01	0.83	FALSE
98	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	IDUA	0.10	0.09	lasso	4	0.11	3.5e-06	-8.95	-8.4	4.1e-17	0.94	0.00	1.00	FALSE
99	The Cancer Genome Atlas	Colon Adenocarcinoma	IDUA	0.09	0.07	blup	50	0.07	4.4e-05	-8.95	-5.3	1.0e-07	0.71	0.00	1.00	FALSE
100	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DGKQ	0.08	0.05	blup	50	0.07	6.9e-08	-7.92	-7.7	1.9e-14	0.71	0.09	0.87	FALSE
101	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IDUA	0.06	0.08	lasso	4	0.07	6.5e-08	-7.92	-8.3	9.4e-17	0.80	0.14	0.86	FALSE
102	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CPLX1	0.10	0.04	lasso	3	0.04	1.1e-05	-4.14	5.8	6.8e-09	-0.14	0.16	0.05	FALSE
103	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DGKQ	0.09	0.05	lasso	4	0.09	8.8e-11	6.28	-9.3	9.6e-21	0.74	0.02	0.98	FALSE
104	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IDUA	0.05	0.02	blup	50	0.01	1.6e-02	4.52	-7.6	2.7e-14	0.83	0.01	0.99	FALSE
105	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DGKQ	0.06	0.01	enet	5	0.02	4.4e-02	6.16	-8.4	3.4e-17	0.62	0.02	0.72	FALSE
106	The Cancer Genome Atlas	Brain Lower Grade Glioma	MAEA	0.03	0.00	blup	61	0.01	1.4e-02	4.96	5.5	4.5e-08	-0.25	0.04	0.67	FALSE
107	The Cancer Genome Atlas	Brain Lower Grade Glioma	SLC26A1	0.11	0.11	blup	53	0.11	1.8e-12	8.20	6.9	4.5e-12	-0.75	0.20	0.80	FALSE
108	The Cancer Genome Atlas	Lung Adenocarcinoma	IDUA	0.06	0.01	enet	10	0.03	2.5e-04	4.56	-5.6	2.8e-08	0.64	0.16	0.56	FALSE
109	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IDUA	0.05	0.01	enet	18	0.02	4.6e-03	-8.17	-6.1	1.3e-09	0.47	0.01	0.59	FALSE
110	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DGKQ	0.11	0.05	blup	49	0.04	7.3e-03	-6.33	-7.2	8.3e-13	0.82	0.01	0.82	FALSE
111	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IDUA	0.08	0.08	lasso	2	0.06	1.4e-03	-8.95	-9.0	2.1e-19	1.00	0.00	0.92	FALSE
112	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SLC26A1	0.24	0.04	blup	53	0.06	2.3e-03	-8.38	5.7	1.0e-08	-0.69	0.00	0.93	FALSE
113	The Cancer Genome Atlas	Stomach Adenocarcinoma	IDUA	0.06	0.02	lasso	2	0.02	1.6e-02	-8.95	-9.0	1.8e-19	0.97	0.00	0.99	FALSE
114	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DGKQ	0.30	0.01	lasso	7	0.07	1.5e-03	-8.38	-7.2	7.9e-13	0.75	0.00	0.75	FALSE
115	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC26A1	0.15	0.11	lasso	4	0.08	8.5e-04	-7.03	7.5	6.5e-14	-0.58	0.03	0.12	TRUE
116	The Cancer Genome Atlas	Thyroid Carcinoma	DGKQ	0.23	0.24	lasso	3	0.32	1.1e-31	-8.36	-8.3	1.3e-16	0.76	0.09	0.91	FALSE
117	The Cancer Genome Atlas	Thyroid Carcinoma	FGFRL1	0.34	0.05	enet	32	0.17	1.2e-16	-4.02	-6.4	1.2e-10	0.31	0.38	0.11	FALSE
118	The Cancer Genome Atlas	Thyroid Carcinoma	SLC26A1	0.09	0.04	blup	53	0.08	8.0e-08	8.20	5.5	4.9e-08	-0.71	0.46	0.54	FALSE