[Hub]/) : Traits : Blood White Count : →

chr1:7,715,776-11,205,058

Best TWAS P=6.21e-15 · Best GWAS P=4.19e-19 conditioned to 1.29e-05

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	YFS	Blood	ENO1	0.07	0.06	lasso	7	0.06	5.1e-19	-7.4	7.8	6.2e-15	-0.64	1.00	0.00	TRUE
7	GTEx	Esophagus Mucosa	RP5-1115A15.1	0.06	0.06	lasso	4	0.05	3.0e-04	5.5	-7.1	1.6e-12	0.16	0.14	0.66	TRUE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	CORT	0.06	0.03	enet	5	0.04	7.1e-04	-5.7	6.6	4.7e-11	-0.01	0.01	0.96	TRUE
27	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PIK3CD	0.06	0.00	enet	5	0.02	2.4e-02	-5.9	-6.5	6.0e-11	-0.03	0.01	0.52	TRUE
23	YFS	Blood	UBE4B	0.03	0.01	bslmm	373	0.02	3.1e-06	-6.1	6.1	1.4e-09	0.00	0.93	0.06	TRUE
12	GTEx	Skin Not Sun Exposed Suprapubic	RP5-1115A15.1	0.08	0.04	enet	8	0.04	3.0e-03	5.5	-5.5	3.6e-08	0.06	0.40	0.06	TRUE
11	GTEx	Pancreas	RERE	0.11	0.12	lasso	4	0.07	5.9e-04	-6.3	-7.2	7.1e-13	0.37	0.30	0.15	FALSE
17	METSIM	Adipose	RERE	0.08	0.12	lasso	17	0.13	1.8e-19	-5.9	-7.1	1.4e-12	0.29	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	RERE	0.20	0.23	lasso	2	0.24	1.7e-19	-6.0	-6.2	6.3e-10	0.22	1.00	0.00	FALSE
3	GTEx	Breast Mammary Tissue	RP5-1115A15.1	0.10	0.07	lasso	2	0.03	7.0e-03	-6.0	-6.0	1.9e-09	0.27	0.63	0.03	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	APITD1	0.05	0.02	blup	51	0.05	3.1e-06	-5.7	-6.0	2.4e-09	0.00	0.01	0.98	FALSE
5	GTEx	Cells Transformed fibroblasts	RERE	0.12	0.08	lasso	4	0.05	6.0e-05	-6.2	-5.9	3.1e-09	0.23	0.94	0.00	FALSE
15	GTEx	Whole Blood	RERE	0.19	0.15	lasso	4	0.13	2.7e-12	5.5	-5.7	1.1e-08	0.03	1.00	0.00	FALSE
4	GTEx	Breast Mammary Tissue (Male)	RP5-1115A15.1	0.18	0.07	lasso	3	0.06	1.7e-02	3.6	-5.7	1.4e-08	0.28	0.06	0.07	FALSE
21	YFS	Blood	RBP7	0.08	0.09	lasso	8	0.09	5.0e-27	-5.5	5.7	1.5e-08	0.02	0.99	0.01	FALSE
29	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CORT	0.12	0.07	lasso	6	0.06	9.3e-05	-5.6	5.7	1.5e-08	-0.04	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CORT	0.04	0.05	lasso	6	0.04	1.7e-04	-5.6	5.6	1.7e-08	-0.05	0.01	0.98	FALSE
16	METSIM	Adipose	APITD1	0.04	0.05	lasso	3	0.03	5.1e-06	-5.4	-5.5	2.9e-08	0.02	0.04	0.96	FALSE
6	GTEx	Esophagus Mucosa	RERE	0.13	0.16	lasso	3	0.16	7.2e-11	5.5	-5.5	3.0e-08	0.01	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	APITD1	0.04	0.03	lasso	3	0.02	1.4e-03	-5.4	-5.5	3.6e-08	0.02	0.01	0.95	FALSE
14	GTEx	Thyroid	RP5-1115A15.1	0.09	0.12	lasso	2	0.09	1.5e-07	5.2	-5.4	6.8e-08	0.02	0.98	0.01	FALSE
22	YFS	Blood	RERE	0.09	0.15	lasso	4	0.16	5.7e-49	5.3	-5.4	7.0e-08	0.02	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PIK3CD	0.23	0.19	enet	7	0.18	1.3e-21	-4.1	-5.4	7.4e-08	-0.04	1.00	0.00	FALSE
32	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RERE	0.12	0.01	enet	10	0.03	4.6e-02	4.6	-5.4	7.8e-08	0.07	0.07	0.13	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	RERE	0.15	0.15	lasso	7	0.15	1.5e-18	-6.0	-5.4	8.0e-08	0.18	1.00	0.00	FALSE
8	GTEx	Lung	RERE	0.07	0.05	lasso	4	0.05	2.0e-04	5.0	-5.2	1.8e-07	0.09	0.87	0.03	FALSE
25	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C1orf200	0.13	0.00	blup	30	0.00	1.8e-01	-6.9	5.2	2.1e-07	0.05	0.00	0.43	FALSE
18	NTR	Blood	RBP7	0.02	0.02	lasso	2	0.02	4.7e-07	-5.3	5.2	2.2e-07	0.00	0.96	0.01	FALSE
10	GTEx	Nerve Tibial	RERE	0.12	0.09	enet	16	0.11	5.6e-08	-6.5	-5.2	2.3e-07	0.16	0.99	0.00	FALSE
9	GTEx	Lung	RP5-1115A15.1	0.05	0.08	lasso	1	0.07	1.0e-05	5.2	-5.2	2.5e-07	0.00	0.59	0.04	FALSE
13	GTEx	Skin Sun Exposed Lower leg	RP5-1115A15.1	0.07	0.03	enet	13	0.03	1.5e-03	5.5	-5.1	2.9e-07	0.13	0.38	0.38	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RERE	0.22	0.04	lasso	10	0.08	4.1e-04	5.5	-5.1	3.0e-07	0.05	0.34	0.04	FALSE