[Hub]/) : Traits : Blood White Count :

chr1:7,715,776-11,205,058

Best TWAS P=6.21e-15 · Best GWAS P=4.19e-19 conditioned to 1.29e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PIK3CD 0.23 0.19 enet 7 0.18 1.3e-21 -4.1 -5.4 7.4e-08 -0.04 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous RERE 0.20 0.23 lasso 2 0.24 1.7e-19 -6.0 -6.2 6.3e-10 0.22 1.00 0.00 FALSE
3 GTEx Breast Mammary Tissue RP5-1115A15.1 0.10 0.07 lasso 2 0.03 7.0e-03 -6.0 -6.0 1.9e-09 0.27 0.63 0.03 FALSE
4 GTEx Breast Mammary Tissue (Male) RP5-1115A15.1 0.18 0.07 lasso 3 0.06 1.7e-02 3.6 -5.7 1.4e-08 0.28 0.06 0.07 FALSE
5 GTEx Cells Transformed fibroblasts RERE 0.12 0.08 lasso 4 0.05 6.0e-05 -6.2 -5.9 3.1e-09 0.23 0.94 0.00 FALSE
6 GTEx Esophagus Mucosa RERE 0.13 0.16 lasso 3 0.16 7.2e-11 5.5 -5.5 3.0e-08 0.01 1.00 0.00 FALSE
7 GTEx Esophagus Mucosa RP5-1115A15.1 0.06 0.06 lasso 4 0.05 3.0e-04 5.5 -7.1 1.6e-12 0.16 0.14 0.66 TRUE
8 GTEx Lung RERE 0.07 0.05 lasso 4 0.05 2.0e-04 5.0 -5.2 1.8e-07 0.09 0.87 0.03 FALSE
9 GTEx Lung RP5-1115A15.1 0.05 0.08 lasso 1 0.07 1.0e-05 5.2 -5.2 2.5e-07 0.00 0.59 0.04 FALSE
10 GTEx Nerve Tibial RERE 0.12 0.09 enet 16 0.11 5.6e-08 -6.5 -5.2 2.3e-07 0.16 0.99 0.00 FALSE
11 GTEx Pancreas RERE 0.11 0.12 lasso 4 0.07 5.9e-04 -6.3 -7.2 7.1e-13 0.37 0.30 0.15 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic RP5-1115A15.1 0.08 0.04 enet 8 0.04 3.0e-03 5.5 -5.5 3.6e-08 0.06 0.40 0.06 TRUE
13 GTEx Skin Sun Exposed Lower leg RP5-1115A15.1 0.07 0.03 enet 13 0.03 1.5e-03 5.5 -5.1 2.9e-07 0.13 0.38 0.38 FALSE
14 GTEx Thyroid RP5-1115A15.1 0.09 0.12 lasso 2 0.09 1.5e-07 5.2 -5.4 6.8e-08 0.02 0.98 0.01 FALSE
15 GTEx Whole Blood RERE 0.19 0.15 lasso 4 0.13 2.7e-12 5.5 -5.7 1.1e-08 0.03 1.00 0.00 FALSE
16 METSIM Adipose APITD1 0.04 0.05 lasso 3 0.03 5.1e-06 -5.4 -5.5 2.9e-08 0.02 0.04 0.96 FALSE
17 METSIM Adipose RERE 0.08 0.12 lasso 17 0.13 1.8e-19 -5.9 -7.1 1.4e-12 0.29 1.00 0.00 FALSE
18 NTR Blood RBP7 0.02 0.02 lasso 2 0.02 4.7e-07 -5.3 5.2 2.2e-07 0.00 0.96 0.01 FALSE
19 ROSMAP Brain Pre-frontal Cortex RERE 0.15 0.15 lasso 7 0.15 1.5e-18 -6.0 -5.4 8.0e-08 0.18 1.00 0.00 FALSE
20 YFS Blood ENO1 0.07 0.06 lasso 7 0.06 5.1e-19 -7.4 7.8 6.2e-15 -0.64 1.00 0.00 TRUE
21 YFS Blood RBP7 0.08 0.09 lasso 8 0.09 5.0e-27 -5.5 5.7 1.5e-08 0.02 0.99 0.01 FALSE
22 YFS Blood RERE 0.09 0.15 lasso 4 0.16 5.7e-49 5.3 -5.4 7.0e-08 0.02 1.00 0.00 FALSE
23 YFS Blood UBE4B 0.03 0.01 bslmm 373 0.02 3.1e-06 -6.1 6.1 1.4e-09 0.00 0.93 0.06 TRUE
24 The Cancer Genome Atlas Bladder Urothelial Carcinoma CORT 0.04 0.05 lasso 6 0.04 1.7e-04 -5.6 5.6 1.7e-08 -0.05 0.01 0.98 FALSE
25 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma C1orf200 0.13 0.00 blup 30 0.00 1.8e-01 -6.9 5.2 2.1e-07 0.05 0.00 0.43 FALSE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma APITD1 0.05 0.02 blup 51 0.05 3.1e-06 -5.7 -6.0 2.4e-09 0.00 0.01 0.98 FALSE
27 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PIK3CD 0.06 0.00 enet 5 0.02 2.4e-02 -5.9 -6.5 6.0e-11 -0.03 0.01 0.52 TRUE
28 The Cancer Genome Atlas Brain Lower Grade Glioma APITD1 0.04 0.03 lasso 3 0.02 1.4e-03 -5.4 -5.5 3.6e-08 0.02 0.01 0.95 FALSE
29 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CORT 0.12 0.07 lasso 6 0.06 9.3e-05 -5.6 5.7 1.5e-08 -0.04 0.01 0.99 FALSE
30 The Cancer Genome Atlas Pancreatic Adenocarcinoma RERE 0.22 0.04 lasso 10 0.08 4.1e-04 5.5 -5.1 3.0e-07 0.05 0.34 0.04 FALSE
31 The Cancer Genome Atlas Stomach Adenocarcinoma CORT 0.06 0.03 enet 5 0.04 7.1e-04 -5.7 6.6 4.7e-11 -0.01 0.01 0.96 TRUE
32 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RERE 0.12 0.01 enet 10 0.03 4.6e-02 4.6 -5.4 7.8e-08 0.07 0.07 0.13 FALSE