[Hub]/) : Traits : Blood White Count :

chr1:113,541,801-115,222,434

Best TWAS P=3.46e-20 · Best GWAS P=2.91e-49 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts OLFML3 0.12 0.00 enet 23 0.00 3.0e-01 -2.0 9.2 3.5e-20 -0.39 0.04 0.49 TRUE
2 GTEx Cells Transformed fibroblasts PHTF1 0.22 0.09 lasso 5 0.19 2.2e-14 -8.8 8.5 1.3e-17 -0.47 1.00 0.00 TRUE
3 GTEx Esophagus Gastroesophageal Junction AP4B1 0.13 0.00 lasso 4 0.01 2.0e-01 7.1 8.0 1.6e-15 -0.47 0.10 0.19 FALSE
4 METSIM Adipose PHTF1 0.10 0.03 blup 517 0.04 1.1e-06 4.2 8.2 3.0e-16 -0.36 0.83 0.09 FALSE
5 ROSMAP Brain Pre-frontal Cortex DCLRE1B 0.08 0.04 enet 14 0.05 2.6e-07 -7.9 6.6 4.6e-11 -0.50 0.97 0.03 FALSE
6 ROSMAP Brain Pre-frontal Cortex RP4-730K3.3 0.08 0.01 blup 477 0.04 8.4e-06 4.7 -5.4 8.2e-08 0.18 0.43 0.02 FALSE
7 YFS Blood PTPN22 0.17 0.02 bslmm 497 0.10 3.8e-30 -1.2 -5.3 1.3e-07 0.25 1.00 0.00 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma DCLRE1B 0.02 0.00 blup 39 0.01 5.2e-03 -4.6 5.7 1.3e-08 -0.47 0.01 0.13 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma PHTF1 0.05 0.02 enet 7 0.03 3.1e-07 -8.8 9.2 3.5e-20 -0.48 0.22 0.63 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma PTPN22 0.02 0.01 blup 67 0.01 9.6e-03 -8.3 -8.8 1.6e-18 0.57 0.11 0.37 TRUE
11 The Cancer Genome Atlas Esophageal Carcinoma DCLRE1B 0.13 0.02 blup 39 0.08 1.8e-03 4.7 7.0 2.9e-12 -0.46 0.01 0.36 FALSE
12 The Cancer Genome Atlas Glioblastoma Multiforme DCLRE1B 0.20 -0.01 blup 39 0.04 3.0e-02 -7.9 7.3 2.9e-13 -0.54 0.00 0.37 TRUE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PHTF1 0.36 0.09 lasso 8 0.12 3.5e-13 4.3 7.5 6.0e-14 -0.35 1.00 0.00 TRUE
14 The Cancer Genome Atlas Prostate Adenocarcinoma PHTF1 0.08 0.03 blup 62 0.05 2.1e-06 -7.6 7.2 6.1e-13 -0.39 0.75 0.01 TRUE
15 The Cancer Genome Atlas Thyroid Carcinoma DCLRE1B 0.06 0.04 enet 11 0.04 4.3e-05 -8.3 7.8 8.2e-15 -0.58 0.04 0.92 TRUE