[Hub]/) : Traits : Blood White Count :

chr15:63,687,200-66,011,630

Best TWAS P=3.79e-24 · Best GWAS P=4.6e-27 conditioned to 0.00372

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TRIP4 0.07 0.06 bslmm 316 0.06 2.2e-07 -6.69 -6.7 2.5e-11 0.27 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous TRIP4 0.12 0.08 lasso 2 0.06 5.6e-06 -7.19 -6.8 8.8e-12 0.39 0.99 0.00 FALSE
3 GTEx Adipose Visceral Omentum TRIP4 0.13 0.09 lasso 2 0.06 5.9e-04 -7.19 -7.2 8.1e-13 0.43 0.53 0.09 FALSE
4 GTEx Adrenal Gland TRIP4 0.09 0.02 lasso 6 0.00 2.9e-01 -6.08 -8.9 5.6e-19 0.72 0.10 0.23 FALSE
5 GTEx Brain Caudate basal ganglia TRIP4 0.18 0.05 lasso 5 0.07 3.7e-03 -7.19 -5.6 1.8e-08 0.26 0.31 0.11 FALSE
6 GTEx Brain Nucleus accumbens basal ganglia TRIP4 0.22 0.09 lasso 3 0.06 8.4e-03 -7.19 -7.0 1.8e-12 0.42 0.11 0.23 FALSE
7 GTEx Breast Mammary Tissue TRIP4 0.14 0.05 enet 6 0.03 6.9e-03 -7.23 -6.5 8.3e-11 0.32 0.88 0.02 FALSE
8 GTEx Breast Mammary Tissue (Female) SNX1 0.04 -0.01 lasso 3 0.04 3.0e-02 -10.04 -10.0 1.1e-23 0.65 0.03 0.09 FALSE
9 GTEx Cells EBV-transformed lymphocytes SNX1 0.26 0.24 enet 8 0.23 4.6e-08 -4.22 -5.4 7.0e-08 0.14 0.77 0.04 TRUE
10 GTEx Cells EBV-transformed lymphocytes TRIP4 0.17 0.21 lasso 3 0.16 4.7e-06 -7.19 -7.1 1.7e-12 0.39 0.58 0.11 FALSE
11 GTEx Cells Transformed fibroblasts TRIP4 0.47 0.36 lasso 3 0.47 1.7e-39 -7.19 -5.2 2.2e-07 0.20 1.00 0.00 FALSE
12 GTEx Cells Transformed fibroblasts RBPMS2 0.07 0.01 lasso 7 0.01 4.3e-02 -6.08 -7.0 2.7e-12 0.63 0.30 0.10 FALSE
13 GTEx Cells Transformed fibroblasts CSNK1G1 0.17 0.17 lasso 1 0.15 1.3e-11 -10.14 -10.1 3.8e-24 0.65 0.49 0.51 TRUE
14 GTEx Colon Transverse TRIP4 0.12 0.10 lasso 2 0.08 9.8e-05 -7.19 -6.4 1.4e-10 0.33 0.90 0.01 FALSE
15 GTEx Esophagus Gastroesophageal Junction TRIP4 0.17 0.14 lasso 6 0.15 3.4e-06 -7.14 -5.7 9.2e-09 0.24 0.76 0.02 FALSE
16 GTEx Esophagus Mucosa TRIP4 0.15 0.08 lasso 6 0.12 1.6e-08 -7.23 -5.8 7.4e-09 0.28 1.00 0.00 FALSE
17 GTEx Esophagus Muscularis TRIP4 0.17 0.18 lasso 10 0.16 7.3e-10 -7.19 -7.3 2.0e-13 0.45 1.00 0.00 FALSE
18 GTEx Heart Atrial Appendage TRIP4 0.13 0.01 lasso 5 0.04 4.9e-03 -7.26 -8.0 1.0e-15 0.54 0.21 0.15 FALSE
19 GTEx Heart Left Ventricle TRIP4 0.09 0.00 enet 8 0.02 1.9e-02 -7.22 -7.7 1.3e-14 0.60 0.21 0.17 FALSE
20 GTEx Lung TRIP4 0.15 0.05 enet 26 0.14 1.2e-10 -7.23 -7.8 6.5e-15 0.50 0.86 0.13 FALSE
21 GTEx Muscle Skeletal TRIP4 0.03 0.01 enet 3 0.01 1.5e-02 -7.19 -7.1 1.2e-12 0.32 0.44 0.12 FALSE
22 GTEx Nerve Tibial TRIP4 0.09 0.08 lasso 2 0.07 8.9e-06 -7.19 -7.0 3.6e-12 0.40 0.98 0.00 FALSE
23 GTEx Skin Not Sun Exposed Suprapubic TRIP4 0.11 0.04 lasso 2 0.04 2.5e-03 -7.19 -6.7 1.9e-11 0.36 0.21 0.10 FALSE
24 GTEx Skin Sun Exposed Lower leg TRIP4 0.11 0.06 lasso 5 0.05 2.4e-05 -7.19 -6.5 7.0e-11 0.32 0.69 0.25 FALSE
25 GTEx Testis TRIP4 0.12 0.06 lasso 5 0.06 1.6e-03 -7.14 -6.0 1.5e-09 0.29 0.16 0.06 FALSE
26 GTEx Whole Blood SNX1 0.09 0.02 lasso 2 0.02 1.3e-02 -4.01 -5.8 8.6e-09 0.34 0.11 0.03 FALSE
27 GTEx Whole Blood RBPMS2 0.32 0.25 lasso 12 0.24 5.9e-22 -7.40 -7.6 2.4e-14 0.74 1.00 0.00 FALSE
28 METSIM Adipose MTFMT 0.03 0.01 bslmm 305 0.01 2.6e-02 -1.73 -5.4 6.9e-08 0.16 0.15 0.20 FALSE
29 METSIM Adipose SNX1 0.04 0.03 enet 27 0.03 1.3e-05 -7.24 -7.5 5.1e-14 0.41 0.98 0.02 FALSE
30 METSIM Adipose TRIP4 0.10 0.18 lasso 12 0.18 9.0e-26 -7.24 -7.1 9.7e-13 0.39 1.00 0.00 FALSE
31 NTR Blood RBPMS2 0.09 0.18 bslmm 276 0.18 1.2e-56 -7.50 -7.4 1.3e-13 0.76 1.00 0.00 FALSE
32 NTR Blood SNX1 0.03 0.02 lasso 1 0.02 6.7e-07 -6.40 -6.4 1.6e-10 0.40 0.98 0.01 FALSE
33 YFS Blood CSNK1G1 0.01 0.00 bslmm 330 0.00 3.0e-02 -8.91 -7.1 1.2e-12 0.47 0.08 0.06 FALSE
34 YFS Blood RBPMS2 0.16 0.29 bslmm 268 0.29 1.1e-96 -7.52 -7.4 1.3e-13 0.76 1.00 0.00 FALSE
35 YFS Blood TRIP4 0.08 0.08 blup 301 0.08 2.0e-24 -7.26 -5.6 2.6e-08 0.26 1.00 0.00 FALSE
36 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIP4 0.08 0.06 enet 5 0.06 1.0e-05 -7.16 -6.2 6.8e-10 0.29 0.91 0.04 FALSE
37 The Cancer Genome Atlas Breast Invasive Carcinoma TRIP4 0.10 0.05 enet 10 0.06 3.4e-12 -7.23 -6.0 2.7e-09 0.21 1.00 0.00 FALSE
38 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TRIP4 0.05 0.01 blup 41 0.03 1.2e-02 -10.10 -9.9 3.7e-23 0.67 0.03 0.33 FALSE
39 The Cancer Genome Atlas Colon Adenocarcinoma TRIP4 0.08 0.03 blup 41 0.04 1.3e-03 -2.47 -7.2 8.6e-13 0.40 0.12 0.11 FALSE
40 The Cancer Genome Atlas Glioblastoma Multiforme SNX1 0.17 0.04 blup 34 0.04 2.0e-02 -6.00 -9.0 2.5e-19 0.59 0.02 0.24 FALSE
41 The Cancer Genome Atlas Glioblastoma Multiforme TRIP4 0.37 0.21 enet 9 0.26 1.8e-08 -7.24 -5.8 8.7e-09 0.24 0.97 0.01 FALSE
42 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RBPMS2 0.05 0.03 lasso 7 0.04 1.6e-05 -7.65 -6.8 8.8e-12 0.69 0.01 0.99 FALSE
43 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TRIP4 0.08 0.05 enet 10 0.07 3.3e-08 -10.10 -9.3 1.4e-20 0.65 0.50 0.49 FALSE
44 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SNX1 0.11 0.05 blup 34 0.05 1.7e-06 -5.59 -5.2 1.7e-07 0.29 0.70 0.26 FALSE
45 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIP4 0.16 0.08 lasso 5 0.08 2.3e-09 -7.23 -6.0 1.9e-09 0.26 1.00 0.00 FALSE
46 The Cancer Genome Atlas Brain Lower Grade Glioma RBPMS2 0.04 0.00 blup 33 0.02 5.0e-03 -7.24 -7.2 6.0e-13 0.45 0.02 0.21 FALSE
47 The Cancer Genome Atlas Brain Lower Grade Glioma TRIP4 0.04 0.02 lasso 4 0.01 1.7e-02 -7.24 -7.2 4.7e-13 0.40 0.29 0.03 FALSE
48 The Cancer Genome Atlas Liver Hepatocellular Carcinoma TRIP4 0.08 0.00 enet 9 0.05 3.3e-03 -10.10 -5.8 5.3e-09 0.47 0.02 0.15 FALSE
49 The Cancer Genome Atlas Lung Adenocarcinoma TRIP4 0.10 0.07 enet 7 0.10 2.1e-11 -2.47 -6.7 2.6e-11 0.31 0.79 0.21 FALSE
50 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PPIB 0.06 0.04 lasso 5 0.03 9.8e-05 -9.36 9.2 2.7e-20 -0.55 0.08 0.69 FALSE
51 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SNX22 0.04 0.03 blup 26 0.03 2.0e-04 -9.36 7.8 7.2e-15 -0.48 0.04 0.40 FALSE
52 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TRIP4 0.04 0.06 lasso 2 0.05 7.9e-07 -7.24 -7.2 4.5e-13 0.40 0.92 0.05 FALSE
53 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TRIP4 0.06 0.04 enet 7 0.06 8.2e-05 -7.24 -7.2 5.1e-13 0.41 0.67 0.02 FALSE
54 The Cancer Genome Atlas Pancreatic Adenocarcinoma TRIP4 0.16 0.04 blup 41 0.10 4.7e-05 -10.07 -6.4 1.3e-10 0.21 0.18 0.17 FALSE
55 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TRIP4 0.21 0.15 lasso 9 0.12 1.2e-05 -7.24 -7.5 8.4e-14 0.43 0.64 0.07 FALSE
56 The Cancer Genome Atlas Prostate Adenocarcinoma TRIP4 0.13 0.07 enet 10 0.08 1.5e-08 -7.24 -6.6 3.8e-11 0.30 0.99 0.01 FALSE
57 The Cancer Genome Atlas Rectum Adenocarcinoma SNX1 0.11 0.12 blup 34 0.13 7.2e-04 -5.59 -7.0 2.9e-12 0.52 0.05 0.26 FALSE
58 The Cancer Genome Atlas Soft Tissue Sarcoma PIF1 0.16 0.02 blup 33 0.10 1.1e-06 0.17 -5.2 1.6e-07 0.22 0.36 0.08 FALSE
59 The Cancer Genome Atlas Stomach Adenocarcinoma SNX1 0.04 0.05 enet 8 0.04 1.1e-03 -5.59 -6.3 3.4e-10 0.37 0.08 0.07 FALSE
60 The Cancer Genome Atlas Stomach Adenocarcinoma TRIP4 0.05 0.00 enet 6 0.03 1.9e-03 -7.16 -7.3 2.7e-13 0.45 0.04 0.13 FALSE
61 The Cancer Genome Atlas Thyroid Carcinoma SNX1 0.09 0.13 lasso 5 0.12 5.8e-12 -4.53 -5.2 1.9e-07 0.40 1.00 0.00 FALSE
62 The Cancer Genome Atlas Thyroid Carcinoma SNX22 0.05 0.07 blup 26 0.06 1.3e-06 -4.53 -6.9 4.1e-12 0.57 0.96 0.02 FALSE