[Hub]/) : Traits : Worry (Nagel 2018) : ← →

chr11:46,578,400-48,559,571

Best TWAS P=9.58e-14 · Best GWAS P=3.33e-11 conditioned to 0.949

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	RP11-750H9.5	0.17	0.25	lasso	6	0.21	3.5e-06	5.5	-5.5	4.3e-08	-0.70	0.24	0.47	FALSE
2	GTEx	Brain Cortex	MTCH2	0.21	0.19	lasso	6	0.16	4.0e-05	-5.4	-5.2	1.6e-07	-0.28	0.32	0.27	FALSE
3	GTEx	Breast Mammary Tissue (Female)	MADD	0.13	0.04	lasso	3	0.05	1.3e-02	-4.9	-5.4	8.4e-08	-0.40	0.06	0.19	FALSE
4	GTEx	Esophagus Gastroesophageal Junction	NUP160	0.18	0.02	enet	18	0.11	7.1e-05	3.6	-5.9	4.6e-09	-0.60	0.08	0.72	FALSE
5	GTEx	Esophagus Muscularis	MTCH2	0.09	0.04	lasso	6	0.02	1.8e-02	-5.7	-6.5	7.9e-11	-0.57	0.24	0.58	FALSE
6	GTEx	Esophagus Muscularis	MADD	0.13	0.07	enet	8	0.11	2.0e-07	4.4	-5.7	9.6e-09	-0.80	0.00	1.00	FALSE
7	GTEx	Liver	C1QTNF4	0.25	0.14	enet	16	0.20	2.3e-06	-3.9	6.1	1.2e-09	0.58	0.28	0.51	FALSE
8	GTEx	Pituitary	MADD	0.42	0.32	lasso	6	0.39	8.9e-11	6.6	-7.4	9.6e-14	-0.89	0.00	1.00	TRUE
9	GTEx	Skin Sun Exposed Lower leg	C1QTNF4	0.25	0.22	lasso	12	0.23	4.2e-19	-3.9	5.1	2.7e-07	0.47	0.63	0.37	FALSE
10	GTEx	Spleen	C1QTNF4	0.31	0.28	enet	29	0.34	1.8e-09	-5.4	5.4	7.7e-08	0.46	0.47	0.50	FALSE
11	GTEx	Whole Blood	C1QTNF4	0.09	0.05	lasso	3	0.03	1.4e-03	-5.4	5.4	5.7e-08	0.35	0.36	0.44	FALSE
12	METSIM	Adipose	C1QTNF4	0.24	0.31	lasso	7	0.31	1.2e-46	-5.7	5.7	1.5e-08	0.34	0.26	0.74	FALSE
13	METSIM	Adipose	NR1H3	0.03	0.03	lasso	6	0.04	4.7e-06	5.4	-5.4	5.6e-08	-0.85	0.02	0.98	FALSE
14	NTR	Blood	MTCH2	0.02	0.04	lasso	1	0.04	1.3e-11	-5.7	5.7	1.5e-08	0.37	0.34	0.66	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	MTCH2	0.35	0.40	enet	9	0.40	4.7e-56	-5.7	-5.5	3.2e-08	-0.37	0.28	0.72	FALSE
16	YFS	Blood	FNBP4	0.02	0.01	bslmm	301	0.01	8.9e-05	5.5	-5.1	2.7e-07	-0.52	0.44	0.31	FALSE
17	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1QTNF4	0.06	0.07	lasso	2	0.06	4.9e-06	-5.7	5.3	9.8e-08	0.36	0.00	0.99	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	MADD	0.11	0.03	enet	14	0.06	1.4e-11	4.4	-5.6	2.3e-08	-0.50	0.26	0.72	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	MYBPC3	0.02	0.01	blup	43	0.01	3.4e-03	-4.9	5.5	3.9e-08	0.46	0.09	0.58	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1QTNF4	0.06	0.08	lasso	3	0.08	7.5e-09	-5.7	5.7	1.2e-08	0.36	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FNBP4	0.10	0.03	blup	45	0.05	7.7e-06	-5.4	-6.0	2.2e-09	-0.36	0.02	0.96	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NUP160	0.08	0.03	blup	42	0.04	6.7e-05	-5.1	-5.7	1.1e-08	-0.35	0.01	0.96	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1QTNF4	0.12	0.14	enet	4	0.16	6.5e-18	-5.7	5.2	2.2e-07	0.35	0.00	1.00	FALSE
24	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1QTNF4	0.13	0.16	lasso	1	0.16	3.1e-09	-5.7	5.7	1.4e-08	0.37	0.00	1.00	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTCH2	0.11	0.11	lasso	2	0.10	6.4e-12	-5.7	-5.7	1.1e-08	-0.37	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1QTNF4	0.19	0.19	lasso	3	0.19	3.2e-09	-5.7	5.7	1.1e-08	0.37	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUP160	0.03	0.02	enet	7	0.02	6.3e-03	-5.4	-6.1	1.1e-09	-0.51	0.01	0.88	FALSE
28	The Cancer Genome Atlas	Stomach Adenocarcinoma	C1QTNF4	0.06	0.04	lasso	4	0.03	4.3e-03	-5.6	5.3	1.2e-07	0.35	0.00	0.91	FALSE