[Hub]/) : Traits : Blood Platelet Count :

chr11:4,838,968-7,371,849

Best TWAS P=6.64e-18 · Best GWAS P=2.66e-28 conditioned to 1.02e-16

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TRIM5 0.06 0.03 enet 25 0.05 3.1e-06 -5.8 8.6 9.3e-18 -0.22 0.64 0.13 FALSE
2 GTEx Esophagus Mucosa TRIM5 0.19 0.04 enet 29 0.05 1.5e-04 -7.4 8.0 1.1e-15 -0.06 0.86 0.01 TRUE
3 GTEx Esophagus Muscularis DCHS1 0.44 0.08 lasso 8 0.22 1.9e-13 4.6 6.0 2.0e-09 -0.04 0.04 0.94 TRUE
4 GTEx Esophagus Muscularis RP11-732A19.5 0.40 0.17 lasso 6 0.17 1.7e-10 4.6 5.9 3.6e-09 -0.03 0.04 0.93 FALSE
5 GTEx Muscle Skeletal TRIM5 0.13 0.07 enet 3 0.05 1.4e-05 -5.8 5.8 7.9e-09 -0.25 1.00 0.00 FALSE
6 GTEx Nerve Tibial RP11-732A19.8 0.12 0.10 lasso 5 0.08 1.7e-06 4.7 5.5 4.1e-08 -0.02 0.01 0.98 FALSE
7 GTEx Nerve Tibial RP11-732A19.2 0.35 0.18 lasso 6 0.19 1.6e-13 4.7 5.3 1.0e-07 -0.01 0.02 0.97 FALSE
8 METSIM Adipose ILK 0.09 0.06 lasso 3 0.05 1.5e-08 4.9 5.2 1.5e-07 -0.04 0.01 0.98 FALSE
9 ROSMAP Brain Pre-frontal Cortex DCHS1 0.24 0.18 lasso 5 0.21 1.2e-26 4.6 5.4 6.1e-08 0.01 0.03 0.94 FALSE
10 ROSMAP Brain Pre-frontal Cortex UBQLNL 0.09 0.00 blup 839 0.02 9.8e-04 4.4 6.5 1.1e-10 -0.18 0.17 0.05 TRUE
11 YFS Blood TRIM5 0.02 0.01 enet 24 0.02 6.7e-07 -3.0 7.4 1.9e-13 0.05 0.99 0.00 TRUE
12 The Cancer Genome Atlas Breast Invasive Carcinoma TRIM5 0.06 0.04 lasso 4 0.04 2.0e-08 -7.4 7.3 2.5e-13 0.02 1.00 0.00 FALSE
13 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TRIM5 0.20 0.00 enet 30 0.08 1.0e-04 -1.7 7.6 3.6e-14 -0.15 0.04 0.04 FALSE
14 The Cancer Genome Atlas Colon Adenocarcinoma TRIM5 0.14 0.03 lasso 6 0.07 9.1e-05 -6.9 6.7 1.7e-11 0.01 0.30 0.06 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TRIM5 0.11 0.10 lasso 1 0.09 1.7e-10 -7.4 7.4 1.3e-13 0.02 1.00 0.00 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIM5 0.07 0.06 lasso 4 0.05 1.1e-06 -7.4 7.4 1.2e-13 0.02 0.98 0.00 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma TRIM5 0.08 0.07 enet 4 0.06 1.2e-07 10.1 8.6 6.6e-18 -0.26 0.95 0.03 TRUE
18 The Cancer Genome Atlas Lung Adenocarcinoma TRIM5 0.08 0.05 lasso 2 0.05 5.6e-07 -7.4 7.4 1.4e-13 0.05 0.97 0.00 FALSE
19 The Cancer Genome Atlas Lung Adenocarcinoma TRIM6 0.04 0.01 blup 113 0.01 6.3e-03 -6.8 7.0 2.2e-12 -0.31 0.04 0.42 FALSE
20 The Cancer Genome Atlas Pancreatic Adenocarcinoma OR52N2 0.12 0.06 lasso 3 0.07 6.1e-04 6.3 -6.9 6.4e-12 -0.03 0.06 0.24 TRUE
21 The Cancer Genome Atlas Thyroid Carcinoma DCHS1 0.10 0.04 lasso 5 0.07 1.3e-07 4.6 5.3 9.5e-08 0.03 0.03 0.86 FALSE