TWAS hub - OR52N2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Lung Adenocarcinoma	0.108	0.0467	4.2e-08	0.031	0.051	0.033	NA	0.049	0.00014	1.1e-06	8.1e-05	NA	2.1e-06
2	TCGA	Pancreatic Adenocarcinoma	0.117	0.0750	2.4e-03	0.064	0.059	0.045	NA	0.072	0.00120	1.8e-03	5.7e-03	NA	6.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Mineral and other dietary supplements	4.1	5.6	8.2	-1.7	-2.9
Rheumatoid Arthritis	3.8	5.2	8.4	1.4	2.9
Neck or shoulder pain in last month	3.4	4.9	5.0	2.2	2.2
Hearing aid user	3.4	3.8	5.1	-1.6	-2.3
Mouth/teeth dental problems: Mouth ulcers	3.3	5.3	6.0	2.5	2.1
Pain experienced in last month	3.3	5.4	7.1	-2.7	-1.9
Fasting Glucose	3.2	3.8	4.9	-2.2	-1.7
Medication: Atenolol	3.1	3.8	5.4	-2.3	-1.5
Knee pain experienced in last month	3.1	4.8	8.0	2.8	1.3
Medication: Cholesterol lowering	3.0	4.7	6.3	-1.7	-2.5
Number of full sisters	3.0	3.7	3.8	1.9	1.9
Supplements: Fish oil (including cod liver oil)	3.0	3.9	6.0	1.4	2.5
Hypothyroidism (self reported)	2.8	6.4	7.4	2.7	2.3
Medication: Levothyroxine sodium	2.8	4.8	5.2	2.1	2.3
Hypothyroidism/myxoedema (self-reported)	2.8	5.4	6.3	2.1	2.5
Average weekly spirits intake	2.7	3.4	3.6	1.9	1.8
Medication: Simvastatin	2.6	3.8	4.9	-1.7	-2.2
Had major operations	2.6	3.0	4.4	-1.3	-2.1
Irritability	2.6	4.4	4.8	2.0	2.2
HbA1C	2.5	2.8	5.2	2.3	0.7
Angina	2.5	3.3	4.9	-2.2	-1.3
Blood Platelet Count	2.4	28.0	47.2	-3.0	-6.9
Qualifications: CSEs or equivalent	2.3	3.1	4.0	2.0	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.3	3.0	5.6	0.7	2.4
Mother’s age at death	2.2	2.7	3.1	1.5	1.8
HDL Cholesterol	2.1	3.4	4.3	2.1	1.6
Major Depression (MDD)	2.0	2.4	4.2	-2.1	-0.7
Coronary Artery Disease (CAD)	2.0	2.4	4.4	2.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.1	6.9	-1.2	-2.6
Miserableness	2.0	3.4	4.2	1.6	2.0
Angina (self-reported)	1.9	2.5	4.0	-2.0	-1.0
Neuroticism (2016)	1.8	2.6	4.7	0.7	2.2
Stomach or abdominal pain in last month	1.8	2.2	2.3	1.4	1.5
Long-standing illness, disability or infirmity	1.8	2.7	4.5	0.9	2.1
Medication: Ibuprofen	1.7	2.1	3.5	0.8	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	2.2	-1.3	-1.5
Ovarian Cancer	1.6	2.1	2.6	1.3	1.6
Had other major operations	1.6	2.0	2.2	1.5	1.3
Loneliness, isolation	1.6	2.2	2.7	1.3	1.7
Medication: Gliclazide	1.6	1.8	2.5	-1.0	-1.6
Vitamin and mineral supplements	1.5	2.0	3.1	-1.0	-1.8
Allergy	1.5	3.5	4.0	-2.0	-1.7
Mouth/teeth dental problems: Dentures	1.5	2.6	3.7	-1.9	-1.2
Lung cancer (father)	1.5	1.8	2.4	1.6	1.1
High blood pressure (siblings)	1.5	2.2	4.1	0.6	2.0
Alcohol intake frequency.	1.5	3.5	5.3	-1.3	-2.3
Chest pain or discomfort	1.5	2.1	2.2	1.4	1.5
Smoking status: Previous	1.5	2.3	3.1	1.8	1.2
High cholesterol (Self-reported)	1.5	2.7	4.4	-1.1	-2.1
Alcohol drinker status: Never	1.5	1.8	2.2	-1.5	-1.2
Number of children fathered	1.4	1.6	3.1	0.4	1.8
Diabetes diagnosed by doctor	1.4	2.3	4.4	-0.3	-2.1
Average weekly fortified wine intake	1.3	1.6	2.6	-0.7	-1.6
Past tobacco smoking	1.3	2.3	3.1	-1.7	-1.3
Medication: Seretide 50 evohaler	1.3	1.5	2.9	0.2	1.7
Suffer from ‘nerves’	1.3	2.0	2.7	1.1	1.6
Commuting to job workplace: Car/motor vehicle	1.3	1.5	2.0	-1.0	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	2.6	-1.6	-0.6
Average weekly red wine intake	1.3	1.9	2.4	1.1	1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	1.7	1.3	1.1
Ever used hormone-replacement therapy (HRT)	1.2	1.5	2.6	-1.6	-0.6
Asthma	1.2	2.4	2.9	1.7	1.4
Length of working week for main job	1.2	1.4	2.4	1.5	0.6
Age at last live birth	1.2	1.7	2.5	1.0	1.6
Commuting to job workplace: Walk	1.2	1.3	1.7	1.0	1.3
Alcohol drinker status: Previous	1.2	1.4	2.2	-0.7	-1.5
Smoking Status	1.1	2.6	3.8	2.0	1.2
High blood pressure (mother)	1.1	1.6	1.9	1.1	1.4
Impedance of arm (left)	1.1	4.9	6.5	2.5	1.8
Migraine (self-reported)	1.1	1.4	1.8	1.3	1.0
Medication: Atorvastatin	1.1	1.3	2.4	-0.6	-1.5
Allergy or Eczema	1.0	2.5	3.3	1.3	1.8
Respiratory disease	1.0	2.2	2.6	1.6	1.3
Medication for hormone replacement therapy	1.0	1.1	1.4	-0.9	-1.2
Medication: Metformin	1.0	1.4	2.8	0.3	-1.7
Diabetes (self-reported)	1.0	1.6	3.1	0.0	-1.8
Neuroticism score	1.0	2.2	3.3	1.0	1.8
Illnesses of mother	1.0	1.2	2.3	-0.4	-1.5
Asthma (self-reported)	1.0	2.1	2.1	1.4	1.4
Illnesses of father: High blood pressure	1.0	1.2	1.3	1.1	1.1
Schizophrenia (2018)	0.9	1.9	2.1	-1.2	-1.5
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	1.5	-1.2	-1.0
Noisy workplace	0.9	1.1	1.7	-1.3	-0.7
Tense / ‘highly strung’	0.9	1.6	1.9	1.4	1.1
Mood swings	0.9	1.6	3.2	0.3	1.8
Medication: Aspirin	0.9	1.2	1.5	-1.0	-1.2
Commuting to job workplace: Public transport	0.9	1.1	1.5	0.8	1.2
Medication: Lisinopril	0.9	1.2	1.9	-1.4	-0.7
Ever depressed for a whole week	0.9	1.1	2.2	0.0	1.5
Heart attack/myocardial infarction (self-reported)	0.9	1.2	1.3	-1.0	-1.1
Crohns Disease (2017)	0.8	1.7	3.3	0.3	1.8
Body Mass Index (BMI) (2010)	0.8	1.1	1.6	1.3	0.7
Crohns Disease (2012)	0.8	1.4	2.4	0.6	1.5
Supplements: Glucosamine	0.8	1.0	1.5	0.7	1.2
Chronic bronchitis/emphysema (father)	0.8	1.0	1.4	1.2	0.7
Pain all over the body in last month	0.8	0.8	1.4	-1.2	0.5
Pulse wave Arterial Stiffness index	0.8	1.0	1.4	-0.7	-1.2
Wheeze or whistling in the chest in last year	0.8	1.4	1.4	1.2	1.2
Pulse wave peak to peak time	0.8	1.0	1.3	0.8	1.1
Emphysema/chronic bronchitis	0.8	0.9	1.7	0.2	1.3
Medication for cholesterol	0.8	1.2	1.8	0.7	1.3
Back pain experienced in last month	0.8	1.1	1.2	1.0	1.1
Wears glasses or contact lenses	0.8	0.9	1.6	0.5	1.3
Impedance of whole body	0.8	4.1	4.4	2.0	2.1
Depressed Affect (Nagel 2018)	0.7	1.4	2.6	0.5	1.6
Schizophrenia (2014)	0.7	1.5	2.2	-1.5	-1.0
Type 2 Diabetes (T2D) (2018)	0.7	1.4	2.7	-0.0	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.6	0.5	1.2
Hayfever, allergic rhinitis or eczema	0.7	1.6	1.7	1.2	1.3
Multivitamins +/- minerals	0.7	0.9	1.7	-0.1	1.3
Heart attack	0.7	0.9	0.9	-0.9	-0.9
Illnesses of siblings	0.7	1.0	1.9	0.1	-1.4
Impedance of arm (right)	0.7	3.2	4.2	2.1	1.5
Prospective memory result	0.7	0.8	1.3	-0.6	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	2.2	-1.5	-1.5
Medication: Ventolin 100micrograms inhaler	0.7	0.9	0.9	1.0	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	1.2	-1.1	-0.7
Medication: Aspirin	0.7	0.9	1.1	-0.9	-1.1
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.6	-1.3	-0.1
Cholesterol lowering medication	0.7	1.1	1.5	-0.8	-1.2
Bipolar Disorder or Schizophrenia	0.6	1.5	1.5	-1.2	-1.2
Alzheimer’s Disease (in mother)	0.6	0.7	1.0	-1.0	0.7
Age at First Birth	0.6	0.8	0.9	1.0	0.8
Mean Putamen Volume	0.6	0.7	0.8	0.9	0.8
Primary Biliary Cirrhosis	0.6	0.9	1.6	-1.3	-0.3
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.3	1.1	-0.2
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.1	-0.6	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	1.9	0.1	1.4
Medication: Ramipril	0.6	0.8	1.6	0.1	-1.3
Time employed in main current job	0.6	0.7	1.3	1.1	-0.3
Father’s age at death	0.6	0.8	1.2	0.7	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.4	0.5	1.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.2	-0.5	1.1
Loud music exposure frequency	0.6	0.7	0.8	-0.9	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.3	1.2	0.3
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	0.8	-0.9	-0.8
Ever had bowel cancer screening	0.6	0.8	1.4	-1.2	-0.4
Number of self-reported non-cancer illnesses	0.6	1.0	1.4	0.8	1.2
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.4	1.2	0.4
Neuroticism (Nagel 2018)	0.5	1.1	2.1	0.2	1.4
Alzheimer’s Disease (in father)	0.5	0.5	0.7	0.8	0.6
Lupus	0.5	0.7	1.4	1.2	-0.0
Relative age of first facial hair	0.5	1.1	2.1	0.3	-1.4
Diabetes (mother)	0.5	0.6	0.7	0.8	0.8
Relative age voice broke	0.5	0.8	0.9	0.9	-0.8
Taking other prescription medications	0.5	0.8	1.0	0.8	1.0
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	1.1	0.2	1.0
Depression (self-reported)	0.5	0.6	0.8	0.9	0.7
Medication: Lansoprazole	0.5	0.5	1.1	0.1	1.0
Pulse wave reflection index	0.5	0.6	0.7	-0.7	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	0.6	-0.8	-0.8
Osteoporosis (self-reported)	0.5	0.6	0.6	-0.8	0.7
LDL Cholesterol	0.4	0.6	0.9	-0.9	0.6
Heel T-Score	0.4	3.0	3.5	1.6	1.9
Sensitivity / hurt feelings	0.4	0.7	1.1	0.4	1.1
Diabetes (father)	0.4	0.4	0.7	-0.8	-0.4
Impedance of leg (left)	0.4	2.1	3.6	0.8	1.9
Nervous feelings	0.4	0.7	1.2	-0.3	1.1
Hair/balding pattern: Pattern 2	0.4	0.5	0.9	-0.0	1.0
Fluid intelligence score	0.4	0.8	1.4	1.2	0.4
Exposure to tobacco smoke at home	0.4	0.5	0.5	-0.7	0.7
Birth weight of first child	0.4	0.8	0.8	0.9	-0.9
Comparative body size at age 10	0.4	1.0	1.7	-0.5	-1.3
Number of full brothers	0.4	0.5	1.0	0.1	1.0
Shortness of breath walking on level ground	0.4	0.5	0.9	1.0	0.0
Mouth/teeth dental problems: Loose teeth	0.4	0.4	0.7	0.4	0.8
Heart disease (mother)	0.4	0.5	0.9	0.1	1.0
Leg pain on walking	0.4	0.6	0.7	0.6	-0.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.7	-0.6	-0.8
Qualifications: nursing, teaching	0.4	0.6	1.2	0.1	-1.1
Breast cancer (self-reported)	0.4	0.5	0.6	-0.8	-0.7
Smoking status: Current	0.4	0.6	1.1	1.0	0.4
Guilty feelings	0.4	0.6	1.0	-0.5	1.0
Ever taken oral contraceptive pill	0.4	0.5	0.5	0.6	0.7
Age started oral contraceptive pill	0.4	0.5	0.9	-0.5	-0.9
Schizophrenia vs Biploar Disorder	0.3	0.4	0.6	-0.5	-0.8
Irritable Bowel Disease (IBD)	0.3	0.7	1.2	0.5	1.1
Breast Cancer	0.3	0.6	1.3	-0.2	-1.1
Triglycerides	0.3	0.4	0.6	-0.7	-0.6
Systolic Blood Pressure	0.3	1.5	2.4	0.7	1.6
Neuroticism	0.3	0.7	1.2	0.4	1.1
Chronotype (morning person)	0.3	0.7	1.4	1.2	0.2
Frequency of depressed mood in last 2 weeks	0.3	0.5	0.8	-0.9	0.3
Impedance of leg (right)	0.3	1.7	2.6	0.9	1.6
Current tobacco smoking	0.3	0.5	0.8	0.9	0.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.7	-0.2	-0.8
Waist circumference	0.3	1.1	2.2	-0.2	-1.5
Mouth/teeth dental problems	0.3	0.4	0.6	0.5	-0.8
Number of live births	0.3	0.4	0.5	0.5	0.7
Breastfed as a baby	0.3	0.3	0.5	0.4	-0.7
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.7	0.5	0.9
Forced vital capacity (FVC), Best measure	0.3	1.1	1.5	-0.8	-1.2
Medication: Omeprazole	0.3	0.3	0.5	-0.4	0.7
Mean time to correctly identify matches	0.3	0.6	1.0	1.0	-0.5
Overall health rating	0.3	0.7	0.8	0.8	0.9
Family relationship satisfaction	0.3	0.4	0.4	0.6	-0.6
Osteoarthritis (self-reported)	0.3	0.4	0.6	-0.5	0.8
Arm fat-free mass (left)	0.3	1.5	2.3	-0.8	-1.5
Ever had prostate specific antigen (PSA) test	0.3	0.4	0.6	-0.4	-0.8
Supplements: Calcium	0.3	0.4	0.7	-0.8	0.2
Basal cell carcinoma (self-reported)	0.3	0.4	0.4	0.6	0.6
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.5	-0.5	-0.7
Heart disease (siblings)	0.3	0.3	0.6	0.8	-0.1
Worry (Nagel 2018)	0.2	0.5	0.9	-0.1	1.0
Alzheimer’s Disease (including proxy)	0.2	0.3	0.4	-0.7	0.4
Ulcerative Colitis (UC)	0.2	0.3	0.3	0.6	0.6
Reaction Time	0.2	0.4	0.7	0.9	-0.3
BMI	0.2	1.3	2.5	-0.3	-1.6
Waist Hip Ratio (WHR)	0.2	1.1	2.2	1.5	0.0
Tanning	0.2	2.9	4.7	1.1	2.2
Number of treatments/medications taken	0.2	0.4	0.6	0.5	0.8
Hearing difficulty/problems: Yes	0.2	0.3	0.7	-0.0	-0.8
Pack years adult smoking proportion	0.2	0.3	0.6	0.8	0.2
Leg fat-free mass (left)	0.2	0.8	1.6	-0.0	-1.3
Trunk fat percentage	0.2	0.9	1.7	1.3	-0.2
Body mass index (BMI)	0.2	0.9	1.8	-0.3	-1.3
Leg predicted mass (left)	0.2	0.8	1.6	-0.0	-1.3
Alcohol usually taken with meals	0.2	0.3	0.4	-0.6	-0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.2	-0.4	0.5
Trunk fat-free mass	0.2	0.9	1.6	-0.5	-1.3
Falls in the last year	0.2	0.3	0.6	0.0	-0.8
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.0	-1.0	-0.5
Pulse rate	0.2	0.4	0.8	-0.0	0.9
Trunk predicted mass	0.2	0.9	1.6	-0.5	-1.3
Standing height	0.2	1.5	2.4	1.6	0.8
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	0.4	0.6	0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.5	0.2	0.7
Medication: Amlodipine	0.2	0.2	0.5	-0.0	-0.7
Exposure to tobacco smoke outside home	0.2	0.3	0.4	0.6	-0.4
Age at first live birth	0.2	0.4	0.4	0.5	0.7
Eye problems/disorders: None of the above	0.2	0.3	0.3	-0.5	0.5
Illnesses of siblings: Diabetes	0.2	0.2	0.2	0.5	0.4
Friendships satisfaction	0.2	0.2	0.3	0.5	-0.3
Eye problems/disorders: Cataract	0.2	0.3	0.5	0.2	0.7
Whole body water mass	0.2	0.9	1.7	-0.4	-1.3
Average weekly champagne plus white wine intake	0.2	0.2	0.3	0.5	-0.4
Financial situation satisfaction	0.2	0.3	0.5	-0.7	-0.2
Eye problems/disorders: Glaucoma	0.2	0.2	0.4	0.0	-0.6
Medication: Blood pressure	0.2	0.3	0.4	-0.6	-0.5
Medication: Bendroflumethiazide	0.2	0.3	0.4	0.6	-0.5
Fractured/broken bones in last 5 years	0.2	0.3	0.4	-0.7	-0.3
Commuting to job workplace: Cycle	0.2	0.3	0.3	0.6	0.5
Pack years of smoking	0.2	0.3	0.6	0.8	0.2
Arm predicted mass (left)	0.2	1.1	1.6	-0.8	-1.3
Bipolar Disorder (2018)	0.1	0.1	0.1	-0.4	-0.2
Depression (Nagel 2018)	0.1	0.2	0.2	-0.3	0.4
Prostate Cancer	0.1	0.1	0.2	0.0	-0.5
Ulcerative Colitis	0.1	0.1	0.1	0.3	-0.3
Blood Eosinophil Count	0.1	0.9	1.1	-0.8	-1.1
Lung FEV1/FVC ratio	0.1	0.6	0.7	-0.8	-0.7
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	0.2	0.4
Medication: Co-codamol	0.1	0.1	0.2	0.3	0.4
Severe depression (siblings)	0.1	0.1	0.2	0.4	0.0
Hand grip strength (right)	0.1	0.4	0.8	-0.0	0.9
Townsend deprivation index at recruitment	0.1	0.1	0.2	-0.1	0.5
Maternal smoking around birth	0.1	0.1	0.2	-0.1	0.5
Fed-up feelings	0.1	0.3	0.5	0.1	0.7
Age when periods started (menarche)	0.1	0.3	0.6	-0.3	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.2	-0.4	-0.5
Serious illness, injury or assault to yourself	0.1	0.1	0.1	0.2	-0.3
Sitting height	0.1	0.7	0.8	0.9	0.8
Trunk fat mass	0.1	0.6	0.9	0.9	-0.6
Number of incorrect matches in round	0.1	0.1	0.2	0.3	-0.4
Hearing difficulty/problems with background noise	0.1	0.1	0.3	0.0	0.5
Forced vital capacity (FVC)	0.1	0.3	0.5	-0.7	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.2	-0.2	-0.4
Qualifications: None of the above	0.1	0.3	0.5	-0.7	0.1
Financial difficulties in last 2 years	0.1	0.1	0.1	0.2	0.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	-0.3	0.2
Weight	0.1	0.7	1.4	0.2	-1.2
Arm fat percentage (right)	0.1	0.5	0.7	0.6	-0.8
Alcohol intake versus 10 years previously	0.1	0.1	0.2	-0.3	-0.4
Worrier / anxious feelings	0.1	0.3	0.4	-0.3	0.7
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.3	0.5	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.1	-0.4	-0.1
Arm fat mass (right)	0.1	0.4	0.8	0.3	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.3	0.4
Peak expiratory flow (PEF)	0.1	0.3	0.4	0.4	0.6
Blood clot in the leg (DVT)	0.1	0.1	0.1	-0.3	-0.4
Gout (self-reported)	0.1	0.2	0.4	-0.1	-0.6
Birth weight	0.1	0.3	0.5	0.7	-0.4
Body fat percentage	0.1	0.4	0.5	0.7	-0.5
Leg fat percentage (right)	0.1	0.2	0.2	0.4	-0.5
Arm fat-free mass (right)	0.1	0.6	1.1	-0.3	-1.0
Worry too long after embarrassment	0.1	0.2	0.3	-0.0	-0.6
Health satisfaction	0.1	0.1	0.1	0.1	0.4
Medication for pain relief, constipation, heartburn	0.1	0.3	0.4	0.6	0.4
Medication: Allopurinol	0.1	0.1	0.2	0.1	-0.5
Whole body fat mass	0.1	0.4	0.4	0.7	-0.6
Leg fat mass (right)	0.1	0.2	0.4	0.2	-0.7
Arm predicted mass (right)	0.1	0.7	1.1	-0.5	-1.0
Pulse rate, automated reading	0.1	0.2	0.3	0.6	0.3
Supplements: Vitamin C	0.1	0.1	0.1	0.4	0.2
Hypertension (Self-reported)	0.1	0.3	0.4	0.7	0.3
Illnesses of father: Heart disease	0.1	0.1	0.1	-0.2	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.5	-0.2	-0.7
Whole body fat-free mass	0.1	0.8	1.5	-0.4	-1.2
Leg fat-free mass (right)	0.1	0.4	0.8	0.0	-0.9
Arm fat percentage (left)	0.1	0.5	0.5	0.7	-0.7
Leg predicted mass (right)	0.1	0.4	0.8	-0.1	-0.9
Arm fat mass (left)	0.1	0.6	1.0	0.4	-1.0
Medication: Paracetamol	0.1	0.2	0.4	-0.6	-0.1
Ever smoked	0.1	0.1	0.2	0.4	0.2
Basal metabolic rate	0.1	0.7	1.4	-0.2	-1.2
Number of operations (self-reported)	0.1	0.1	0.1	-0.4	0.1
Average weekly beer plus cider intake	0.1	0.1	0.2	0.3	-0.4
Risk taking	0.1	0.2	0.3	-0.2	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.3	-0.2	0.5
Leg fat mass (left)	0.1	0.3	0.5	0.0	-0.7
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.1	0.3	0.1
Verbal and Numeric Reasoning (VNR)	0.0	0.0	0.0	0.1	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	-0.0	0.2
Blood Red Count	0.0	0.0	0.0	0.2	-0.1
Blood White Count	0.0	0.3	0.5	0.3	-0.7
Height	0.0	0.4	0.6	0.8	-0.4
Cardiovascular Disease	0.0	0.2	0.2	-0.4	-0.4
Lung FVC	0.0	0.2	0.5	-0.7	-0.1
Hair Pigment	0.0	0.9	1.1	-0.9	-1.1
Hand grip strength (left)	0.0	0.1	0.2	0.2	0.5
Systolic blood pressure, automated reading	0.0	0.1	0.1	-0.3	0.2
Supplements: Zinc	0.0	0.0	0.0	-0.1	0.1
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.0	-0.2	0.2
High blood pressure	0.0	0.0	0.0	0.2	-0.2
Had menopause	0.0	0.0	0.1	0.0	-0.3
Hip circumference	0.0	0.2	0.4	-0.1	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.0	-0.1	0.1
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	-0.1	-0.1
Happiness	0.0	0.0	0.0	0.0	0.2
Hair/balding pattern: Pattern 4	0.0	0.0	0.0	-0.2	-0.1
Medication: Paracetamol	0.0	0.1	0.1	-0.2	0.2
Headache pain in last month	0.0	0.1	0.1	0.4	-0.0
Glaucoma (self-reported)	0.0	0.0	0.1	0.2	-0.0
Chronic bronchitis/emphysema (mother)	0.0	0.1	0.1	-0.2	-0.3
Qualifications: College or University degree	0.0	0.1	0.2	0.3	0.4
Medication: Blood pressure	0.0	0.0	0.1	-0.3	-0.1
Comparative height size at age 10	0.0	0.0	0.0	0.1	0.1
Illnesses of father: None of the above (group 1)	0.0	0.1	0.1	0.3	-0.1
Leg fat percentage (left)	0.0	0.1	0.2	0.3	-0.4
Diastolic blood pressure, automated reading	0.0	0.1	0.2	-0.4	-0.1
Unable to work because of sickness or disability	0.0	0.1	0.1	-0.2	-0.3
Myopia	0.0	0.0	0.0	-0.1	-0.1
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.2	0.4	0.2

Hub : Genes

OR52N2

Models

Trait associations