TWAS hub - DCHS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0810	0.0350	6.2e-03	0.084	0.030	0.062	0.088	0.079	1.9e-10	1.2e-04	4.4e-08	7.8e-11	7.2e-10
2	GTEx	Artery Aorta	0.1790	0.0580	2.5e-04	0.045	NA	0.020	NA	0.047	1.6e-03	NA	2.6e-02	NA	1.3e-03
3	GTEx	Esophagus Muscularis	0.4350	0.0740	8.9e-07	0.080	NA	0.181	NA	0.219	1.3e-05	NA	3.6e-11	NA	1.9e-13
4	GTEx	Nerve Tibial	0.1327	0.0513	3.0e-03	0.027	NA	0.002	NA	0.010	4.7e-03	NA	2.4e-01	NA	6.4e-02
5	METSIM	Adipose	0.0599	0.0244	3.8e-03	0.043	0.012	0.034	0.033	0.045	4.9e-07	5.7e-03	5.9e-06	7.6e-06	2.0e-07
6	ROSMAP	Brain Pre-frontal Cortex	0.2418	0.0510	1.6e-11	0.184	0.103	0.204	0.199	0.211	4.3e-23	4.1e-13	1.1e-25	5.0e-25	1.2e-26
7	YFS	Blood	0.0714	0.0180	9.6e-10	0.062	0.033	0.065	0.063	0.063	2.0e-19	4.0e-11	1.6e-20	1.1e-19	1.1e-19
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0491	0.0225	1.9e-03	0.016	0.026	0.033	NA	0.018	5.5e-03	5.6e-04	1.2e-04	NA	4.0e-03
9	TCGA	Brain Lower Grade Glioma	0.0476	0.0225	1.6e-03	0.050	0.032	0.025	NA	0.044	2.1e-06	1.4e-04	6.1e-04	NA	8.9e-06
10	TCGA	Thyroid Carcinoma	0.0980	0.0370	3.7e-06	0.038	0.073	0.070	NA	0.073	1.3e-04	1.4e-07	2.2e-07	NA	1.3e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Average weekly beer plus cider intake	5.3	7.7	12.1	-2.3	-3.0	-2.8	-2.8	-1.6	-2.7	-3.1	-3.4	-2.1	-3.5
Age started oral contraceptive pill	5.0	6.3	9.1	2.7	2.7	3.0	2.5	2.0	2.6	3.0	1.0	2.6	2.4
Wears glasses or contact lenses	4.4	5.1	9.4	2.1	2.7	2.3	3.1	1.5	2.0	2.4	1.4	2.1	2.5
Schizophrenia vs Biploar Disorder	4.2	5.5	11.6	-2.3	-1.4	-1.7	-1.8	-1.1	-2.7	-3.2	-3.4	-2.0	-2.6
Commuting to job workplace: Public transport	4.2	5.1	7.7	2.1	2.5	2.2	1.0	2.7	2.2	2.4	1.6	2.3	2.8
Exposure to tobacco smoke outside home	4.1	5.4	12.6	-2.2	-2.0	-2.5	-2.4	-0.9	-2.4	-2.7	-3.5	-1.8	-1.9
Impedance of arm (left)	3.9	18.1	32.1	3.9	3.7	5.7	4.7	3.5	4.2	4.1	4.3	3.5	4.5
Alcohol usually taken with meals	3.8	6.2	10.1	2.2	2.8	3.0	2.5	1.9	2.3	2.7	1.9	2.1	3.2
Handedness (chirality/laterality): Left-handed	3.6	4.3	7.6	-2.4	-2.7	-2.0	-1.1	-2.3	-1.8	-2.1	0.1	-2.4	-2.5
Qualifications: None of the above	3.4	7.2	13.1	-3.6	-1.3	-2.9	-1.6	-2.8	-3.1	-3.6	-1.1	-3.1	-2.4
Schizophrenia (2018)	3.2	6.6	11.1	-2.8	-1.4	-3.1	-2.2	-1.5	-3.0	-3.3	-2.5	-2.7	-2.3
Had menopause	3.2	3.9	8.2	2.2	2.9	2.0	1.2	1.7	2.3	1.9	0.3	2.5	1.7
Qualifications: CSEs or equivalent	3.0	4.0	7.1	-2.7	-2.1	-1.2	-1.4	-1.8	-2.5	-2.4	-0.8	-2.4	-1.8
Father’s age at death	3.0	4.1	7.2	2.5	1.9	1.6	-0.4	2.5	2.4	2.2	0.1	2.7	2.0
Stomach or abdominal pain in last month	2.9	3.6	7.9	-2.2	-2.5	-0.7	0.4	-1.9	-2.5	-2.3	0.2	-2.8	-1.1
Average weekly red wine intake	2.9	4.3	7.3	2.4	1.9	1.8	1.5	2.2	2.2	2.7	0.2	2.5	2.2
Ever had stillbirth, spontaneous miscarriage or termination	2.8	3.0	5.0	1.8	2.2	0.9	1.8	1.1	1.6	2.2	2.1	1.2	2.0
Impedance of arm (right)	2.7	12.4	22.9	3.1	2.8	4.8	4.0	2.7	3.4	3.4	4.2	2.6	3.5
Supplements: Vitamin C	2.7	3.2	12.6	-1.5	-3.5	-1.0	-0.7	-1.2	-1.8	-1.6	-0.3	-1.7	-2.4
Ever used hormone-replacement therapy (HRT)	2.6	3.3	5.4	1.8	2.1	1.3	2.3	1.9	2.0	1.1	1.2	2.0	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	2.6	3.4	5.6	-2.0	-1.6	-1.4	-1.2	-1.7	-2.1	-2.2	-2.4	-1.8	-1.7
Number of children fathered	2.5	2.8	8.4	1.2	1.2	1.4	2.3	-0.1	1.8	2.1	2.9	1.0	1.2
Tinnitus: Yes, now most or all of the time	2.4	2.9	5.3	1.4	1.3	1.5	2.2	1.6	1.9	2.3	1.3	1.6	1.3
Pack years of smoking	2.4	3.5	5.3	-1.5	-2.2	-2.0	-2.3	-2.0	-1.9	-1.7	-1.6	-1.8	-1.4
Pack years adult smoking proportion	2.3	3.5	5.9	-1.6	-2.4	-2.0	-2.2	-2.1	-1.9	-1.6	-1.2	-1.9	-1.6
Qualifications: O levels/GCSEs or equivalent	2.2	3.6	6.7	1.8	0.8	2.4	1.5	1.5	2.3	2.6	2.4	1.6	1.0
Blood Platelet Count	2.1	24.8	36.0	4.9	4.6	6.0	4.8	4.4	5.4	5.0	4.4	4.6	5.3
Qualifications: nursing, teaching	2.1	3.2	5.9	1.9	1.0	2.1	1.7	2.1	1.8	2.4	1.0	1.9	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.1	4.4	6.4	2.5	2.5	2.2	0.9	1.5	2.2	2.3	1.1	2.4	2.4
Medication: Atorvastatin	2.1	2.6	4.6	-1.8	-1.8	-1.7	-1.4	-1.8	-1.4	-1.2	0.1	-2.0	-2.2
Qualifications: A levels/AS levels or equivalent	2.0	4.4	7.0	2.1	0.8	2.5	2.3	1.6	2.3	2.6	2.6	2.0	1.3
Verbal and Numeric Reasoning (VNR)	1.9	4.5	11.9	2.1	1.2	3.4	3.2	1.2	2.4	1.8	1.0	2.2	0.8
Schizophrenia (2014)	1.9	4.3	7.3	-2.2	-0.8	-2.7	-1.7	-0.6	-2.5	-2.7	-2.0	-2.1	-2.1
Smoking Status	1.9	4.5	8.8	-3.0	-2.1	-1.7	-1.4	-2.0	-2.3	-1.9	0.7	-2.7	-2.5
Qualifications: College or University degree	1.9	5.9	10.6	2.6	2.9	2.0	1.4	2.4	2.3	3.3	1.9	2.3	2.8
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	5.2	-1.1	-1.8	-1.2	-2.3	-1.3	-1.5	-1.5	-1.8	-1.0	-1.3
Breast cancer (self-reported)	1.9	2.2	6.8	1.2	1.1	0.7	1.9	0.4	1.4	1.8	2.6	0.9	1.7
Bipolar Disorder or Schizophrenia	1.8	4.4	7.4	-2.6	-1.3	-2.7	-1.4	-1.2	-2.5	-2.6	-1.0	-2.4	-2.2
HbA1C	1.8	2.0	4.0	0.7	1.5	1.9	1.9	0.8	1.3	0.9	1.6	0.7	2.0
Tinnitus: Yes, but not now, but have in the past	1.8	2.0	3.0	-1.3	-1.7	-1.3	-1.2	-1.6	-1.6	-1.7	-0.1	-1.4	-1.3
Mineral and other dietary supplements	1.8	2.4	5.4	1.9	0.8	1.6	0.9	1.2	1.8	2.3	0.5	1.9	1.7
Medication: Allopurinol	1.7	2.3	3.7	-1.7	-1.0	-1.4	-1.3	-1.0	-1.9	-1.7	-1.9	-1.4	-1.3
Heart disease (mother)	1.7	2.0	4.7	1.1	2.2	1.0	0.8	1.0	1.6	1.6	1.8	1.3	1.4
Smoking status: Current	1.7	2.8	6.2	-2.0	-2.2	-1.4	-0.7	-1.0	-1.4	-1.6	0.8	-2.0	-2.5
Ever taken oral contraceptive pill	1.7	1.8	4.4	1.4	0.3	2.1	1.2	1.2	1.7	1.8	0.1	1.6	0.7
Financial difficulties in last 2 years	1.6	2.1	4.0	-1.6	-1.6	-1.1	-1.6	-1.2	-1.6	-1.0	-0.4	-1.8	-2.0
Angina (self-reported)	1.6	2.1	4.1	-1.9	-0.9	-1.7	-0.4	-1.3	-2.0	-1.8	-0.6	-1.9	-0.3
Migraine (self-reported)	1.6	2.0	4.6	2.0	0.9	1.3	0.5	0.7	1.7	1.8	0.4	2.1	1.0
Angina	1.5	2.0	3.9	-1.9	-0.8	-1.7	-0.3	-1.4	-2.0	-1.7	-0.7	-1.8	-0.3
Loud music exposure frequency	1.5	1.7	4.1	-1.3	-2.0	-1.5	-1.1	-0.5	-0.8	-1.2	0.5	-1.1	-2.0
Gout (self-reported)	1.5	2.0	3.0	-1.5	-1.1	-1.4	-1.4	-1.0	-1.7	-1.5	-1.3	-1.5	-1.5
Had major operations	1.5	1.7	3.6	1.4	0.8	1.7	1.9	0.3	1.5	1.7	0.9	1.2	0.6
Trunk fat percentage	1.4	5.6	13.9	2.2	3.7	2.6	2.5	2.1	2.2	1.3	0.6	2.4	2.8
Fluid intelligence score	1.4	3.0	5.6	1.9	1.1	2.4	2.1	1.3	2.1	1.9	0.4	2.2	0.7
Ever highly irritable/argumentative for 2 days	1.4	1.6	3.0	-1.7	-1.7	-0.5	-0.3	-1.4	-1.4	-1.3	0.1	-1.3	-1.7
Comparative height size at age 10	1.4	7.5	12.1	2.9	1.4	3.1	3.5	2.5	3.1	3.0	3.0	2.4	1.7
Mother’s age at death	1.4	1.8	3.7	1.2	1.3	1.4	0.8	1.1	1.5	1.0	1.5	1.2	1.9
Current tobacco smoking	1.3	2.2	4.6	-1.8	-1.8	-1.2	-0.5	-0.8	-1.3	-1.5	0.8	-1.9	-2.1
Triglycerides	1.2	2.0	4.5	-1.7	-0.7	-1.1	-2.1	-1.0	-1.9	-1.5	-1.2	-1.5	-0.9
Type 2 Diabetes (T2D) (2012)	1.2	1.4	2.6	-0.9	-0.9	-0.6	-1.4	-1.2	-1.5	-1.6	-1.6	-1.0	-0.6
Systolic Blood Pressure	1.2	5.9	14.2	-1.9	-3.6	-2.7	-2.7	-0.7	-2.1	-1.9	-1.0	-1.9	-3.8
Medication: Co-codamol	1.2	1.3	3.9	-0.7	-1.0	-1.5	-1.0	-2.0	-1.1	-0.9	0.5	-1.2	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.5	-1.5	-1.6	-0.9	1.0	-1.2	-1.1	-1.4	-0.4	-1.4	-1.0
Arm fat percentage (left)	1.2	5.0	11.7	2.1	3.4	2.6	2.2	1.9	2.1	1.1	0.1	2.4	2.7
Financial situation satisfaction	1.2	1.5	3.5	-1.4	-1.5	-0.3	-0.9	-0.7	-1.3	-1.6	-0.8	-1.1	-1.9
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	2.7	-1.4	-0.6	-1.1	-0.5	-1.1	-1.3	-1.6	-0.8	-1.1	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	3.7	-1.3	-1.5	-1.5	-1.1	-1.9	-1.8	-1.9	-1.4	-1.4	-1.3
Birth weight of first child	1.1	2.0	5.6	1.3	1.0	2.4	1.6	0.7	1.1	1.3	0.8	1.3	1.8
Alcohol drinker status: Never	1.1	1.4	4.5	0.8	0.9	0.9	0.2	1.2	1.0	1.2	2.1	1.0	1.3
Number of operations (self-reported)	1.1	1.6	9.9	0.6	0.7	1.4	3.1	0.1	1.1	0.8	0.8	0.7	0.9
Unable to work because of sickness or disability	1.1	1.5	2.3	-1.3	-0.9	-0.6	-1.5	-1.4	-1.3	-1.0	-1.5	-1.0	-1.3
Cholesterol lowering medication	1.1	1.7	3.2	-1.6	-0.6	-0.7	0.5	-1.3	-1.1	-1.8	1.6	-1.7	-1.2
Alzheimer’s Disease (in father)	1.0	1.0	2.1	0.9	1.5	0.8	0.9	1.4	1.1	0.3	1.1	1.0	0.8
Diabetes (father)	1.0	1.2	3.2	-1.1	-0.9	-0.5	-1.6	-0.5	-1.4	-1.8	-0.9	-1.0	-0.9
Past tobacco smoking	1.0	1.8	3.9	2.0	0.9	1.0	0.7	1.9	1.4	1.0	-0.2	1.6	1.7
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	5.0	-1.0	-2.2	-0.2	0.1	-0.6	-1.1	-1.2	-0.6	-1.0	-1.4
Length of working week for main job	1.0	1.1	5.2	0.7	0.4	1.1	2.3	0.1	0.6	0.8	1.4	0.4	0.6
Number of full brothers	1.0	1.3	3.2	-1.8	-0.9	-0.0	0.9	-1.4	-1.3	-1.2	-0.1	-1.5	-0.4
Ever smoked	1.0	1.8	3.5	-1.9	-0.9	-1.2	-1.1	-1.3	-1.6	-1.0	0.1	-1.8	-1.6
Heart disease (siblings)	1.0	1.2	4.7	-0.4	-0.2	-1.0	-1.7	-0.0	-0.8	-1.2	-2.2	-0.2	-0.8
Impedance of whole body	1.0	5.0	9.5	1.8	2.0	2.6	2.3	1.9	2.0	2.3	3.1	1.4	2.5
Coronary Artery Disease (CAD)	0.9	1.1	2.5	-1.1	-1.1	-1.0	-1.0	-0.5	-1.0	-1.1	0.3	-1.3	-1.6
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	2.2	-1.1	-0.9	-1.2	-0.8	-1.1	-1.5	-1.0	-0.9	-1.2	-0.6
Trunk fat mass	0.9	3.7	8.9	1.9	3.0	2.0	2.0	1.8	1.9	1.0	0.3	2.1	2.1
Illnesses of siblings	0.9	1.3	3.6	1.5	0.2	0.3	0.8	0.2	1.3	1.7	1.9	0.9	0.8
Arm fat percentage (right)	0.9	3.5	8.0	1.7	2.8	2.3	2.0	1.6	1.7	0.8	-0.0	1.9	2.1
Asthma	0.9	1.7	5.2	0.9	1.1	1.7	2.3	0.8	1.2	1.2	1.6	0.5	0.9
High blood pressure (siblings)	0.9	1.4	4.9	-1.5	-0.1	-0.2	-0.4	-0.7	-1.5	-1.3	-2.2	-1.1	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	4.3	0.3	1.1	1.4	2.1	1.0	0.8	0.9	0.4	0.7	-0.2
Medication: Omeprazole	0.9	1.1	2.7	-1.3	0.4	-1.0	-0.4	-1.7	-1.3	-1.1	-0.7	-1.1	0.7
Loneliness, isolation	0.9	1.2	2.3	-0.9	-1.0	-1.4	-1.4	-0.6	-1.5	-1.0	-0.9	-1.0	-1.0
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.2	-1.3	-0.6	-1.3	-1.1	-0.5	-1.1	-1.5	-0.4	-1.0	-1.5
Myopia	0.9	1.3	3.3	-1.2	-1.7	-0.3	0.1	-1.3	-0.9	-1.0	-0.9	-0.8	-1.8
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.1	-1.3	-1.4	0.1	0.5	-1.0	-1.3	-1.3	0.2	-1.4	-0.6
Average weekly fortified wine intake	0.8	1.0	1.6	1.2	-0.2	0.9	0.5	1.2	1.0	1.3	1.2	1.1	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.0	-1.1	-1.3	-0.0	-0.7	-0.8	-1.3	-1.4	-0.5	-1.3	-0.9
Lung cancer (father)	0.8	0.9	2.1	-0.7	-1.3	-1.3	-1.4	-0.4	-0.6	-0.5	-0.2	-0.6	-1.4
Tense / ‘highly strung’	0.8	1.4	2.8	-1.3	-1.7	-0.5	0.7	-1.0	-1.2	-1.6	-1.0	-1.2	-1.0
Body fat percentage	0.8	3.1	10.8	1.6	3.3	1.6	1.4	1.6	1.5	0.6	-0.3	1.8	2.2
Illnesses of father: Heart disease	0.8	1.1	2.3	-1.3	-1.0	-1.4	-0.7	-0.7	-0.9	-1.5	0.2	-1.2	-0.6
Miserableness	0.8	1.4	2.3	-1.2	-1.2	-1.5	-0.0	-1.3	-0.8	-1.2	0.7	-1.4	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	2.9	-1.0	-1.4	-0.1	-0.1	-0.9	-0.7	-1.4	-1.7	-0.7	-1.1
Fasting Glucose	0.7	0.8	2.5	-0.9	-0.3	-0.3	-0.8	-0.8	-1.4	-1.0	-1.6	-0.8	-0.3
Systolic blood pressure, automated reading	0.7	2.0	6.3	-0.8	-0.9	-1.7	-2.5	-0.8	-1.2	-1.3	-1.5	-0.6	-1.9
Serious illness, injury or assault to yourself	0.7	0.9	2.9	0.7	-0.5	0.4	1.7	-0.0	0.6	1.1	1.7	0.3	0.7
Medication: Atenolol	0.7	0.9	3.1	0.7	1.5	0.4	0.7	1.2	0.5	0.4	-0.5	0.8	1.8
Hair/balding pattern: Pattern 2	0.7	0.9	1.5	-1.1	-0.1	-1.2	-0.9	-0.8	-1.2	-1.2	-0.9	-1.2	-0.5
Hip circumference	0.7	3.0	7.6	1.8	2.8	1.4	1.7	2.0	1.5	0.9	-0.5	2.1	1.8
Blood clot in the leg (DVT)	0.7	1.0	2.8	-0.7	-1.4	-0.0	0.0	-0.7	-0.5	-1.4	-1.7	-0.5	-1.2
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	2.7	-1.0	-1.0	-1.4	-0.6	-1.1	-1.1	-1.6	0.4	-1.1	-1.1
Forced vital capacity (FVC), Best measure	0.7	2.5	4.3	2.0	0.3	2.1	1.0	1.7	1.8	2.0	1.3	1.8	0.7
Worry too long after embarrassment	0.7	1.2	4.0	0.5	1.7	0.9	1.7	0.4	0.3	0.5	0.8	0.2	2.0
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.8	-1.0	-1.3	-0.6	-0.4	-1.4	-0.6	-0.3	1.1	-1.0	-0.9
Medication: Blood pressure	0.7	1.2	3.5	1.2	0.6	1.3	0.6	1.1	1.2	1.9	0.2	1.0	0.7
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	1.8	1.1	1.2	1.2	-0.1	1.3	0.9	1.1	-0.2	1.1	1.0
Medication: Gliclazide	0.7	0.8	1.4	-0.8	-1.1	-0.7	1.0	-0.6	-0.4	-0.8	1.2	-1.0	-0.8
Medication: Blood pressure	0.7	1.4	4.7	-1.2	-0.1	-1.6	-0.0	-1.3	-1.1	-2.2	0.3	-1.2	-0.9
High cholesterol (Self-reported)	0.7	1.3	3.5	-1.6	-0.4	-0.6	-0.3	-0.9	-1.5	-1.3	1.0	-1.9	-0.8
Ever depressed for a whole week	0.7	0.9	1.7	-0.9	-1.0	-0.1	1.2	-1.2	-0.8	-0.9	0.9	-1.3	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	3.0	-0.7	1.4	-0.3	0.1	-0.8	-0.8	-0.7	-0.8	-0.5	1.7
LDL Cholesterol	0.6	1.0	2.2	0.7	1.4	1.2	-0.0	1.2	0.8	1.1	0.4	0.8	1.5
Respiratory disease	0.6	1.3	4.3	1.1	1.0	1.1	2.1	0.9	1.4	0.9	0.6	0.8	0.8
Average weekly spirits intake	0.6	0.8	2.5	0.6	0.9	0.5	-0.8	1.0	0.8	1.1	0.1	0.5	1.6
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.6	-0.6	-1.4	-0.6	-0.1	-0.3	-0.4	-1.0	-0.7	-0.3	-1.6
Vitamin and mineral supplements	0.6	0.9	2.4	0.9	1.6	-0.1	-0.4	0.9	0.9	1.0	-0.5	1.2	0.9
Townsend deprivation index at recruitment	0.6	0.9	1.8	-1.3	-0.7	-1.1	-1.2	-0.6	-0.9	-1.0	-0.1	-1.1	-0.8
Age when periods started (menarche)	0.6	1.3	2.7	-1.5	0.1	-1.4	-1.2	-0.9	-1.3	-1.1	0.5	-1.6	-1.0
Noisy workplace	0.6	0.7	2.1	-1.1	-1.0	-1.4	-0.4	-1.0	-0.5	-0.1	-0.1	-0.9	-0.8
Depression (self-reported)	0.6	0.7	2.7	0.3	1.3	0.5	0.5	0.3	-0.1	0.1	-1.1	0.5	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	2.9	1.7	0.0	1.7	0.9	1.2	1.5	1.7	1.6	1.4	0.6
Pulse wave Arterial Stiffness index	0.6	0.6	1.9	0.6	0.8	1.1	1.4	0.3	0.8	0.9	0.3	0.8	0.4
Exposure to tobacco smoke at home	0.6	0.7	4.2	-0.3	0.1	-1.0	-0.4	-0.2	-0.6	-1.0	-2.1	-0.2	-0.2
Glaucoma (self-reported)	0.6	0.8	1.8	1.0	1.4	-0.1	-0.4	1.1	1.0	0.9	0.5	0.7	0.8
Neck or shoulder pain in last month	0.6	0.8	3.5	-0.4	-1.9	-0.5	-0.6	-0.0	-0.3	-0.7	-0.5	-0.3	-1.8
Overall health rating	0.6	1.3	2.8	-1.4	-0.9	-0.5	-0.5	-1.2	-1.6	-1.4	-0.9	-1.7	-0.3
Knee pain experienced in last month	0.6	0.9	3.8	-1.2	-0.2	-0.0	-0.9	-0.2	-1.2	-0.7	-2.0	-0.9	0.5
Illnesses of siblings: Diabetes	0.6	0.8	2.8	-1.2	0.1	-0.6	-1.0	-0.0	-0.9	-1.7	-0.8	-0.8	-0.4
Smoking status: Previous	0.6	1.0	2.8	-1.4	-0.3	-0.9	-0.9	-1.7	-1.0	-0.7	-0.2	-0.9	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	2.6	0.3	-1.6	1.0	1.6	1.0	0.8	0.5	1.6	0.3	-1.6
Medication for cholesterol	0.6	0.8	2.9	0.3	0.5	0.5	-1.7	0.5	0.0	1.0	-1.7	0.7	0.5
Asthma (self-reported)	0.6	1.2	3.2	0.7	0.9	1.4	1.8	0.7	1.0	1.0	1.4	0.3	0.8
Intelligence (Savage-Jansen 2018)	0.5	1.5	4.4	1.1	-0.0	1.6	2.1	0.9	1.6	0.9	0.8	1.3	-0.0
Reaction Time	0.5	1.0	1.8	-1.2	-0.3	-1.1	-0.9	-1.1	-1.2	-1.3	-0.5	-1.2	-0.5
Body Mass Index (BMI) (2010)	0.5	0.6	1.4	-1.2	-0.7	-0.2	0.6	-0.6	-1.1	-1.1	-0.4	-1.1	-0.2
Lupus	0.5	0.7	2.1	1.1	-0.2	0.5	0.2	1.1	1.3	0.7	-0.5	1.5	-0.1
Blood Red Count	0.5	5.0	17.1	-1.3	-0.6	-3.2	-4.1	-1.0	-1.7	-2.4	-2.6	-1.0	-1.7
Relative age of first facial hair	0.5	1.1	4.6	-0.5	-2.1	0.6	1.1	-1.1	-0.7	-1.0	0.4	-1.0	-0.8
Diabetes (mother)	0.5	0.7	2.1	0.9	-0.2	0.8	0.1	1.0	0.6	0.2	-1.4	0.9	-0.8
Alcohol intake versus 10 years previously	0.5	0.8	1.8	-1.0	-0.4	-0.9	-0.6	-0.7	-1.2	-0.7	-1.3	-0.9	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.8	-0.1	0.2	1.4	1.7	0.2	0.3	0.4	1.5	-0.2	0.8
Prospective memory result	0.5	0.6	3.7	-0.1	-0.3	-0.4	-1.9	-0.1	-0.6	-0.2	-1.0	-0.1	-0.5
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.0	-0.5	-0.7	0.9	1.2	0.5	-0.2	-0.2	1.4	-0.8	-0.4
Birth weight	0.5	1.2	3.1	1.2	0.3	0.4	0.9	0.9	1.4	0.9	1.8	0.8	1.3
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.3	0.1	1.1	1.1	1.1	0.4	0.4	0.4	0.4	0.3	1.1
Age at first live birth	0.5	0.9	2.1	1.4	-0.2	-0.2	-0.8	0.6	1.0	1.1	-1.2	1.4	-0.7
Eye problems/disorders: None of the above	0.5	0.5	1.3	0.6	0.2	1.2	1.0	0.3	0.7	0.5	-0.0	0.9	0.9
Whole body fat mass	0.5	2.2	6.9	1.4	2.6	1.4	1.3	1.5	1.4	0.5	-0.7	1.7	1.4
Pulse rate, automated reading	0.5	1.5	2.6	-1.4	-0.4	-1.4	-1.6	-1.2	-1.3	-0.7	0.3	-1.6	-1.4
Suffer from ‘nerves’	0.5	0.8	3.7	-0.1	0.7	0.4	1.9	0.2	0.5	-0.0	1.1	0.2	1.4
Age at last live birth	0.5	0.7	2.0	-0.1	-1.1	-0.5	-1.2	-0.6	-0.5	-0.3	-1.4	-0.3	-1.3
Commuting to job workplace: Car/motor vehicle	0.5	0.5	1.9	-0.0	-0.5	0.9	1.2	-0.8	-0.1	-0.0	1.4	-0.5	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.5	-1.2	-0.7	-0.4	0.6	-0.5	-0.9	-1.1	-0.4	-1.1	-0.5
Commuting to job workplace: Walk	0.5	0.5	2.9	-0.3	-1.7	-0.8	-0.7	-0.1	-0.5	-0.4	-0.5	-0.4	-0.3
Medication: Paracetamol	0.5	0.8	2.3	-0.8	-1.3	-0.5	-0.1	-0.8	-0.4	-0.5	1.5	-1.0	-0.9
Medication: Lisinopril	0.5	0.7	1.5	1.2	0.5	0.6	1.2	0.2	1.2	0.6	0.5	0.8	0.5
Worry (Nagel 2018)	0.4	0.8	3.6	-1.1	-0.5	-0.6	0.7	-0.6	-0.9	-1.9	-0.3	-1.0	-0.1
Alzheimer’s Disease (in mother)	0.4	0.4	1.3	0.8	-0.1	0.5	0.2	1.2	0.8	0.4	-0.1	0.8	0.6
Alzheimer’s Disease (including proxy)	0.4	0.6	2.8	0.9	0.3	0.4	0.5	1.7	1.1	0.3	0.2	1.0	0.4
Crohns Disease (2017)	0.4	0.9	3.5	-0.5	0.7	-1.2	-1.1	0.5	-0.9	-0.7	-1.9	-0.7	0.2
Major Depression (MDD)	0.4	0.4	2.4	0.5	0.2	0.9	0.8	-0.1	0.2	0.4	-0.2	-0.0	1.6
Prostate Cancer	0.4	0.6	2.1	-0.0	0.1	-1.0	-1.4	-0.2	-0.7	-1.0	-0.8	-0.2	0.4
Crohns Disease (2012)	0.4	0.7	3.0	0.2	1.7	-0.3	0.2	1.0	0.0	-0.1	-1.1	-0.0	1.1
Rheumatoid Arthritis	0.4	0.5	1.5	-0.1	0.3	1.2	1.2	0.0	0.3	0.5	1.2	-0.1	0.6
Blood White Count	0.4	3.3	5.9	-2.3	-0.7	-1.2	-1.7	-2.3	-2.4	-2.0	-0.4	-2.4	-1.6
Heel T-Score	0.4	3.2	7.5	-2.0	-2.7	-1.1	-0.3	-1.9	-1.3	-1.9	-0.1	-1.7	-2.7
Height	0.4	7.9	13.7	2.9	1.3	2.8	3.6	2.3	3.1	3.2	3.7	2.4	1.7
Ever had hysterectomy (womb removed)	0.4	0.4	2.7	-0.5	0.0	0.0	1.6	-0.3	-0.6	-0.6	0.3	-0.7	0.3
Medication for hormone replacement therapy	0.4	0.4	1.9	0.4	-1.1	0.1	1.4	0.0	0.3	0.1	0.4	-0.0	-0.6
Severe depression (siblings)	0.4	0.4	1.1	-0.7	-1.1	0.0	0.7	-0.8	-0.3	-0.5	0.1	-0.6	-0.8
Relative age voice broke	0.4	0.6	1.3	-1.0	-0.3	-0.3	-0.3	-1.1	-1.0	-1.0	-0.6	-1.1	-0.3
Taking other prescription medications	0.4	0.6	1.4	-0.8	0.0	0.3	1.0	-0.6	-0.5	-1.2	1.0	-0.9	0.2
Sitting height	0.4	2.8	5.0	1.9	0.5	1.8	1.9	2.0	1.8	2.2	1.6	1.6	0.6
High blood pressure (mother)	0.4	0.6	1.2	-0.5	-1.0	-0.4	-0.9	-0.3	-0.7	-1.0	-1.1	-0.5	-1.0
Time employed in main current job	0.4	0.4	0.9	0.3	0.9	0.4	0.5	0.9	0.5	0.8	1.0	0.5	0.1
Medication: Cholesterol lowering	0.4	0.6	1.9	-0.6	-1.0	-0.6	-0.7	-0.2	-0.8	-0.3	-1.4	-0.8	-0.7
Medication: Lansoprazole	0.4	0.4	3.0	-0.0	0.9	0.0	0.0	-0.4	-0.3	-0.1	0.2	-0.3	1.7
Arm fat mass (right)	0.4	1.6	4.9	1.1	2.2	1.5	1.2	1.1	1.1	0.2	-0.4	1.4	1.1
Standing height	0.4	3.9	6.7	2.0	0.3	2.4	2.5	2.0	2.1	2.2	2.6	1.7	0.4
Breastfed as a baby	0.4	0.5	2.3	0.5	0.3	0.6	1.5	-0.5	0.5	0.3	1.1	-0.1	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	2.6	0.1	0.9	1.0	1.6	1.1	0.5	0.5	0.1	0.4	0.6
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.6	-1.2	-1.2	-0.6	-0.4	-0.4	-1.3	-0.9	-0.1	-1.1	-0.8
Pulse wave peak to peak time	0.4	0.5	1.4	-0.5	-0.8	-0.8	-1.2	-0.1	-0.7	-0.7	-0.2	-0.7	-0.3
Health satisfaction	0.4	0.5	2.4	-0.1	-0.2	0.9	0.7	0.9	0.4	0.3	1.6	-0.2	0.2
Medication for pain relief, constipation, heartburn	0.4	0.7	1.4	1.0	0.5	0.6	0.2	1.2	0.9	0.8	-0.3	1.2	1.0
Medication: Seretide 50 evohaler	0.4	0.4	2.6	-0.1	-1.1	0.0	-0.2	0.4	0.1	-0.2	-0.1	-0.1	-1.6
Mood swings	0.4	0.6	1.7	-0.7	-1.1	-0.2	1.0	-0.3	-0.4	-0.9	0.6	-0.6	-1.3
Friendships satisfaction	0.4	0.4	1.0	-0.1	-0.9	-0.2	-0.4	0.5	-0.6	-1.0	-1.0	-0.2	-0.8
Back pain experienced in last month	0.4	0.6	2.9	-0.0	1.7	0.4	0.4	0.1	-0.3	-0.7	-0.1	-0.2	1.5
Osteoarthritis (self-reported)	0.4	0.5	3.5	0.0	0.3	-0.7	-1.9	0.2	-0.3	-0.3	-0.4	0.1	-0.4
Arm fat mass (left)	0.4	1.8	4.8	1.3	2.2	1.5	1.3	1.2	1.3	0.4	-0.3	1.6	1.2
Average weekly champagne plus white wine intake	0.4	0.6	1.5	1.0	-0.2	-0.3	-1.2	0.9	0.9	0.4	-0.1	1.1	-0.5
Pain type(s) experienced in last month: Hip pain	0.4	0.6	2.4	0.5	1.6	0.4	0.1	0.8	0.6	0.3	-0.9	0.8	0.5
Alcohol drinker status: Previous	0.4	0.4	2.6	0.2	0.7	-0.1	-0.1	-0.1	-0.0	-0.2	-1.6	0.5	0.8
Bipolar Disorder (2018)	0.3	0.4	2.4	-0.6	-0.3	-0.5	0.6	-0.1	-0.2	0.1	1.6	-0.6	-0.5
Irritable Bowel Disease (IBD)	0.3	0.8	2.7	-0.5	1.0	-1.0	-0.7	0.8	-0.8	-0.8	-1.6	-0.5	0.3
Hearing difficulty/problems: Yes	0.3	0.5	2.1	0.3	0.2	0.7	1.5	0.3	0.8	-0.2	0.8	0.3	0.4
Medication: Metformin	0.3	0.4	1.7	0.8	0.6	0.4	0.4	1.3	0.8	0.6	0.3	0.7	0.0
Maternal smoking around birth	0.3	0.4	1.7	0.1	0.7	0.2	0.5	0.4	-0.5	-0.3	-1.3	0.1	0.9
Fed-up feelings	0.3	0.5	1.1	0.5	-0.5	0.8	0.8	0.3	0.9	0.3	0.6	0.6	-1.1
Hayfever, allergic rhinitis or eczema	0.3	0.8	2.3	-0.8	-0.0	-0.8	-1.2	0.5	-1.0	-0.5	-1.5	-0.7	-0.7
Multivitamins +/- minerals	0.3	0.4	0.7	-0.8	-0.8	0.3	0.0	-0.5	-0.6	-0.7	0.0	-0.8	-0.8
Supplements: Glucosamine	0.3	0.3	0.9	-0.6	-0.6	-0.7	-0.4	-0.3	-0.6	-0.4	0.3	-0.8	-0.9
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.1	0.2	0.2	0.1	1.0	0.8	0.3	0.4	0.1	0.2	1.1
Medication: Levothyroxine sodium	0.3	0.5	1.2	-0.5	-1.0	-0.1	0.4	0.1	-0.7	-0.9	-1.0	-0.4	-1.1
Number of incorrect matches in round	0.3	0.5	1.7	0.3	0.9	1.3	0.5	1.0	0.3	0.9	-0.4	0.4	0.5
Hearing difficulty/problems with background noise	0.3	0.5	1.3	-0.4	-0.9	0.6	1.1	0.1	-0.3	-0.8	-0.9	-0.3	-0.9
Had other major operations	0.3	0.3	0.8	0.5	0.5	0.7	0.9	0.0	0.8	0.3	-0.4	0.7	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.6	-0.9	-0.8	-0.7	-0.6	-1.3	-1.1	-1.2	-0.5	-1.0	-0.5
Medication: Ramipril	0.3	0.4	1.5	-0.3	0.1	0.5	1.2	-0.6	0.1	0.5	1.0	-0.3	-0.6
Neuroticism score	0.3	0.7	2.1	-1.1	-0.5	-0.6	0.4	-0.8	-0.9	-1.4	-0.6	-0.9	-0.9
Pulse rate	0.3	0.5	1.6	0.8	0.7	0.6	1.3	0.3	0.9	0.7	0.6	0.5	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.8	-0.5	0.4	-0.7	-0.4	-0.8	-0.6	-0.3	0.1	-0.6	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	2.0	0.1	-0.4	-0.5	-0.5	0.1	-0.1	0.8	-0.3	-0.1	-1.4
Pulse wave reflection index	0.3	0.3	0.8	-0.9	-0.8	-0.6	-0.2	-0.6	-0.6	-0.5	0.1	-0.7	-0.2
Medication: Paracetamol	0.3	0.6	2.6	-0.5	-0.9	-0.1	0.4	-0.6	-0.2	-0.2	1.6	-0.8	-0.8
Headache pain in last month	0.3	0.6	1.1	-0.7	-0.9	1.1	1.0	-0.6	-0.8	-0.8	0.0	-0.9	-0.1
Medication: Ibuprofen	0.3	0.4	2.1	-0.0	-0.8	-0.5	-0.6	-0.1	-0.1	0.8	0.1	-0.3	-1.4
Family relationship satisfaction	0.3	0.3	1.5	-0.2	-0.8	0.4	0.8	-0.1	0.0	-0.5	0.3	-0.0	-1.2
Medication: Aspirin	0.3	0.4	1.1	-0.8	-0.0	0.0	0.2	-0.6	-1.1	-1.1	-0.3	-0.7	-0.3
Ever had bowel cancer screening	0.3	0.4	1.3	-0.3	0.4	-0.8	-0.6	-1.0	-0.5	-0.0	-1.1	-0.1	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.9	0.4	1.2	0.3	0.3	-0.1	0.5	-0.0	-0.2	0.5	1.4
Osteoporosis (self-reported)	0.3	0.4	2.0	0.0	0.5	0.7	1.4	0.2	0.4	0.3	0.4	-0.0	0.7
Medication: Aspirin	0.3	0.4	0.9	-0.9	-0.1	0.3	0.4	-0.6	-1.0	-0.8	-0.1	-0.8	-0.5
Eye problems/disorders: Glaucoma	0.3	0.4	1.2	0.6	0.7	-0.7	-1.1	0.8	0.5	0.4	-0.1	0.4	0.2
Medication: Bendroflumethiazide	0.3	0.5	1.4	-0.5	-0.7	-0.5	0.2	-1.2	-0.7	-1.0	0.3	-0.6	-0.8
Illnesses of father: High blood pressure	0.3	0.3	1.8	0.3	-0.3	-1.0	-1.3	0.3	0.1	0.0	-0.3	0.4	-0.3
Leg fat percentage (left)	0.3	0.9	4.0	0.3	2.0	-0.8	-0.7	0.3	-0.2	-0.7	-1.6	0.4	0.7
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.7	0.3	0.9	0.1	-0.7	-0.4	-0.0	-0.0	-1.3	0.3	0.8
Pain experienced in last month	0.3	0.4	1.5	0.7	0.2	-0.2	0.9	-0.2	0.7	0.8	1.2	0.5	-0.0
Arm predicted mass (left)	0.3	1.6	4.2	-1.0	-1.1	-1.6	-1.2	-0.6	-1.1	-1.4	-1.4	-0.7	-2.1
Ulcerative Colitis (UC)	0.2	0.4	0.8	-0.5	0.8	-0.9	-0.4	0.3	-0.7	-0.5	-0.8	-0.5	0.2
Ovarian Cancer	0.2	0.2	0.7	-0.5	0.5	0.1	-0.1	-0.2	0.4	0.6	0.8	-0.2	-0.6
Age at First Birth	0.2	0.3	2.3	-0.4	0.4	-0.5	-1.5	0.0	-0.4	0.3	-0.4	-0.2	0.3
Mean Putamen Volume	0.2	0.2	0.8	-0.4	-0.3	-0.6	-0.9	-0.0	-0.4	-0.3	-0.2	-0.3	-0.3
HDL Cholesterol	0.2	0.3	0.8	-0.5	0.2	-0.8	-0.2	-0.9	-0.5	-0.5	0.3	-0.4	-0.5
Ulcerative Colitis	0.2	0.3	0.7	-0.6	0.8	-0.7	0.1	0.6	-0.4	-0.5	-0.2	-0.6	0.1
Waist Hip Ratio (WHR)	0.2	0.9	3.2	-0.6	-1.8	0.2	0.7	-0.6	-0.4	-0.5	1.3	-1.0	-1.4
Neuroticism	0.2	0.4	0.9	-0.6	-0.8	0.2	0.5	-0.3	-0.5	-1.0	-0.7	-0.4	-0.8
Hand grip strength (left)	0.2	0.5	2.2	0.2	-1.1	-0.3	0.0	-0.4	0.4	0.7	1.5	0.1	-0.8
Sensitivity / hurt feelings	0.2	0.3	0.8	-0.2	0.8	-0.2	0.4	-0.2	-0.7	-0.9	-0.7	-0.2	0.1
Supplements: Zinc	0.2	0.2	0.5	0.3	-0.1	0.3	0.7	0.5	0.3	0.4	-0.5	0.4	0.6
Chronic bronchitis/emphysema (father)	0.2	0.3	1.2	-0.4	-1.1	-0.2	0.7	-0.3	-0.2	-0.5	0.1	-0.5	-0.5
Nervous feelings	0.2	0.4	1.8	-0.7	-0.1	0.5	1.3	-0.2	-0.5	-1.0	-0.0	-0.5	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	2.1	-0.2	0.5	0.7	1.4	0.0	-0.4	-0.4	0.3	-0.4	0.4
Heart attack	0.2	0.2	0.5	-0.6	-0.3	-0.2	0.6	-0.2	-0.5	-0.2	-0.7	-0.4	-0.5
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.7	-0.1	-0.1	-0.2	-0.6	0.9	0.0	-0.3	0.7	-0.0	-0.6
Medication: Simvastatin	0.2	0.3	1.1	-0.3	0.7	0.9	1.0	0.4	-0.2	-0.4	0.2	-0.1	0.5
Worrier / anxious feelings	0.2	0.4	1.3	0.3	0.5	1.1	1.1	0.5	0.5	0.0	0.9	0.4	0.5
Hair/balding pattern: Pattern 3	0.2	0.3	1.2	-0.1	0.6	-0.4	-1.1	-0.4	-0.1	0.0	-0.8	0.2	-0.2
Mouth/teeth dental problems: Dentures	0.2	0.4	0.9	-0.6	0.4	-0.7	-0.7	-0.9	-0.5	-0.8	-0.2	-0.4	0.1
Illnesses of mother	0.2	0.2	0.4	-0.2	-0.6	-0.5	-0.6	-0.5	-0.4	0.2	-0.3	-0.3	-0.6
Peak expiratory flow (PEF)	0.2	0.5	1.9	-0.2	-1.4	0.4	0.7	-0.7	-0.2	0.3	0.9	-0.5	-0.9
Leg fat percentage (right)	0.2	0.7	2.9	0.1	1.7	-0.6	-0.9	0.2	-0.2	-0.7	-1.5	0.3	0.6
Arm fat-free mass (right)	0.2	0.9	2.2	-0.4	-0.7	-1.3	-1.0	-0.3	-0.7	-0.9	-1.3	-0.3	-1.5
Emphysema/chronic bronchitis	0.2	0.2	0.7	0.5	-0.4	0.2	0.4	0.8	0.5	0.5	-0.4	0.4	-0.4
Mean time to correctly identify matches	0.2	0.4	1.7	0.1	1.3	0.1	-0.4	-0.2	-0.0	-0.6	-0.5	0.3	1.1
Arm predicted mass (right)	0.2	1.0	2.5	-0.5	-0.8	-1.5	-1.0	-0.3	-0.7	-1.0	-1.3	-0.3	-1.6
Alcohol intake frequency.	0.2	0.5	2.0	0.8	1.4	-0.0	0.1	0.0	0.4	0.3	-0.6	0.8	1.1
Number of full sisters	0.2	0.2	0.4	-0.5	-0.2	0.1	0.4	-0.3	-0.4	-0.5	0.7	-0.6	-0.1
Chest pain or discomfort	0.2	0.2	0.8	0.5	0.5	0.1	0.3	0.6	0.4	-0.1	-0.9	0.5	0.5
Leg pain on walking	0.2	0.3	1.2	0.4	0.3	-0.1	-0.8	0.3	0.5	1.1	0.4	0.6	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.4	0.3	-0.1	-0.0	-0.4	-0.1	0.3	0.3	-0.5	0.4	-1.2
Illnesses of father: None of the above (group 1)	0.2	0.3	1.0	0.3	0.9	0.2	-0.1	-0.2	-0.0	1.0	-0.3	0.2	0.8
Number of self-reported non-cancer illnesses	0.2	0.3	1.0	-0.5	0.8	0.0	1.0	0.8	-0.3	-0.4	0.3	-0.5	0.0
Arm fat-free mass (left)	0.2	1.2	3.6	-0.8	-1.0	-1.4	-0.9	-0.5	-0.9	-1.1	-1.3	-0.6	-1.9
Irritability	0.2	0.4	1.3	-0.2	-1.0	0.2	0.7	-0.9	-0.1	-0.5	-0.0	-0.2	-1.2
Fractured/broken bones in last 5 years	0.2	0.2	0.9	0.8	-0.2	0.4	-0.3	0.0	0.3	0.5	-0.3	0.6	-0.9
Commuting to job workplace: Cycle	0.2	0.2	0.9	-0.2	-0.4	-0.6	-0.3	-0.0	-0.2	0.2	0.3	-0.3	-1.0
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.9	-0.6	-0.9	-0.8	-1.4	-0.7	-0.7	-0.6	-0.3	-0.5	-0.5
Basal cell carcinoma (self-reported)	0.2	0.2	0.6	0.0	0.4	0.8	0.1	0.6	0.4	0.4	0.4	0.2	-0.2
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.5	-0.5	-0.5	-0.1	0.7	-0.2	-0.4	-0.1	-0.6	-0.4	-0.6
Leg fat mass (left)	0.2	0.6	2.7	0.1	1.4	-0.5	-0.3	0.3	-0.1	-0.8	-1.6	0.3	-0.0
Depressed Affect (Nagel 2018)	0.1	0.1	0.7	0.2	-0.5	-0.2	0.0	0.2	-0.0	-0.4	-0.2	0.1	-0.8
Depression (Nagel 2018)	0.1	0.1	0.4	0.1	-0.3	0.6	0.2	0.1	-0.2	-0.3	-0.7	-0.1	0.2
Neuroticism (Nagel 2018)	0.1	0.2	1.0	0.0	-0.2	-0.0	0.6	0.5	-0.2	-1.0	-0.2	-0.0	-0.0
Breast Cancer	0.1	0.2	0.6	-0.5	0.3	0.2	-0.0	-0.7	-0.5	-0.3	-0.0	-0.2	-0.8
Neuroticism (2016)	0.1	0.1	0.4	0.6	-0.1	0.2	0.4	0.3	0.3	0.6	0.2	0.6	-0.1
Primary Biliary Cirrhosis	0.1	0.2	1.3	-0.5	0.1	-0.2	0.2	0.2	-0.3	-0.0	-1.1	-0.4	-0.2
Blood Eosinophil Count	0.1	0.8	2.1	-1.4	-0.7	0.1	-0.3	-0.6	-1.2	-1.0	-1.0	-1.2	-0.3
BMI	0.1	0.7	2.4	0.9	0.7	0.9	0.2	0.9	0.6	-0.1	-1.6	1.2	0.3
Allergy or Eczema	0.1	0.2	0.8	-0.4	0.6	-0.4	-0.9	0.4	-0.4	0.0	-0.5	-0.4	-0.3
Cardiovascular Disease	0.1	0.2	0.8	-0.5	0.0	-0.3	-0.1	0.4	-0.1	-0.4	0.3	-0.5	-0.9
Hypothyroidism (self reported)	0.1	0.3	0.6	-0.5	-0.8	-0.1	-0.6	0.4	-0.7	-0.3	-0.4	-0.4	-0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.6	0.3	-0.1	0.4	1.3	0.0	0.1	-0.1	0.2	0.0	-0.1
Lung FEV1/FVC ratio	0.1	0.3	1.3	0.5	-0.0	-0.8	-0.3	0.6	0.4	-0.3	1.1	0.3	0.4
Lung FVC	0.1	0.7	3.3	0.5	1.4	0.9	0.3	-0.2	0.3	0.5	0.2	0.7	1.8
Chronotype (morning person)	0.1	0.3	1.4	-0.3	-0.6	-0.0	-0.2	-0.3	-0.2	-0.8	-0.7	-0.2	-1.2
Tanning	0.1	0.9	1.6	-1.1	-0.7	-1.3	-0.3	-1.0	-1.1	-1.1	-0.8	-1.0	-0.5
Number of treatments/medications taken	0.1	0.2	0.7	-0.7	0.5	0.0	0.5	-0.3	-0.3	-0.3	0.8	-0.7	-0.2
Impedance of leg (right)	0.1	0.4	2.1	-0.4	-0.1	-0.6	-0.7	0.2	-0.4	0.4	1.4	-0.8	0.1
Leg fat-free mass (left)	0.1	0.7	1.6	0.8	0.2	1.2	1.3	0.7	0.8	0.1	-0.4	1.1	-0.4
Hand grip strength (right)	0.1	0.4	1.3	0.5	-0.1	-0.1	-0.1	0.3	0.8	1.0	1.1	0.7	-0.3
High blood pressure	0.1	0.3	0.9	0.4	0.8	0.2	0.9	0.5	0.7	0.3	0.4	0.4	0.2
Body mass index (BMI)	0.1	0.6	3.2	-0.0	1.0	-0.3	-0.1	-0.0	-0.2	-1.1	-1.8	0.4	0.0
Impedance of leg (left)	0.1	0.5	1.4	-0.4	0.1	-1.0	-0.8	0.1	-0.6	0.1	1.2	-1.0	0.1
Leg predicted mass (left)	0.1	0.7	1.8	0.8	0.2	1.3	1.3	0.7	0.8	0.1	-0.3	1.0	-0.3
Waist circumference	0.1	0.5	1.1	0.3	1.0	0.7	1.0	1.0	0.3	-0.5	-0.7	0.6	0.3
Forced vital capacity (FVC)	0.1	0.5	0.9	0.9	-0.8	0.9	0.3	0.6	0.5	0.9	-0.0	0.7	-0.7
Mouth/teeth dental problems	0.1	0.2	0.7	0.4	-0.8	-0.3	0.3	-0.2	0.1	-0.1	-0.8	0.3	-0.5
Allergy	0.1	0.1	0.3	0.4	0.2	-0.0	-0.3	-0.4	0.5	0.2	0.5	0.5	0.1
Pain all over the body in last month	0.1	0.1	0.4	-0.3	-0.1	0.4	0.0	0.3	-0.0	0.6	-0.6	0.1	-0.4
Diabetes (self-reported)	0.1	0.2	0.6	0.7	-0.0	0.4	0.5	0.5	0.5	0.2	0.1	0.6	-0.1
Weight	0.1	0.6	1.3	0.8	1.1	0.8	0.9	0.8	0.7	-0.1	-0.6	1.1	0.2
Trunk fat-free mass	0.1	0.5	2.3	-0.2	-1.3	-0.6	-0.4	-0.1	-0.4	-0.5	-0.5	-0.2	-1.5
Falls in the last year	0.1	0.2	0.6	0.3	-0.6	-0.2	0.6	0.1	0.4	0.1	0.8	0.2	0.0
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.8	0.5	-0.9	0.4	0.1	0.2	0.2	0.5	0.4	0.3	-0.6
Happiness	0.1	0.2	0.4	-0.5	-0.4	0.2	0.2	0.6	-0.1	-0.3	0.6	-0.2	-0.5
Trunk predicted mass	0.1	0.5	2.4	-0.3	-1.3	-0.7	-0.4	-0.1	-0.4	-0.5	-0.5	-0.3	-1.6
Medication: Amlodipine	0.1	0.1	0.4	-0.1	-0.4	-0.1	-0.6	-0.2	-0.5	-0.1	-0.6	-0.2	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.6	-0.1	0.8	0.5	-0.1	0.1	-0.1	-0.4	0.1	-0.3	0.1
Comparative body size at age 10	0.1	0.2	0.7	-0.7	0.4	-0.1	-0.8	-0.4	-0.2	0.3	0.0	-0.2	-0.4
Wheeze or whistling in the chest in last year	0.1	0.2	1.1	0.2	1.1	-0.1	0.4	0.8	0.1	0.3	-0.1	0.1	-0.0
Shortness of breath walking on level ground	0.1	0.1	0.3	-0.0	-0.1	-0.1	0.2	0.5	-0.2	0.1	-0.6	-0.1	0.1
Leg fat mass (right)	0.1	0.5	2.5	0.1	1.4	-0.3	-0.3	0.3	0.0	-0.7	-1.6	0.4	0.0
Hypertension (Self-reported)	0.1	0.2	1.0	0.3	1.0	-0.0	0.5	0.4	0.4	0.3	0.2	0.2	0.4
Leg fat-free mass (right)	0.1	0.6	1.8	0.8	0.1	1.2	1.4	0.7	0.8	0.1	-0.4	1.0	-0.4
Long-standing illness, disability or infirmity	0.1	0.2	0.6	-0.7	0.5	-0.5	0.8	-0.2	-0.5	-0.0	0.1	-0.5	0.3
Diabetes diagnosed by doctor	0.1	0.1	0.4	0.2	-0.5	-0.2	0.5	0.0	0.3	-0.2	0.3	0.0	-0.6
Leg predicted mass (right)	0.1	0.6	1.8	0.8	0.1	1.2	1.4	0.7	0.8	0.0	-0.4	1.1	-0.4
Guilty feelings	0.1	0.2	0.9	-0.4	-0.2	-0.2	0.4	0.6	-0.4	-1.0	-0.5	-0.3	-0.2
Hearing aid user	0.1	0.1	0.3	-0.2	0.2	0.5	0.2	-0.4	0.1	-0.2	0.2	0.1	0.5
Risk taking	0.1	0.1	0.6	-0.1	0.2	0.3	-0.0	-0.1	0.1	0.8	0.5	0.0	0.5
Diastolic blood pressure, automated reading	0.1	0.2	1.4	-0.5	-0.3	-0.4	-0.4	-0.3	-0.4	-0.3	-0.1	-0.3	-1.2
Supplements: Calcium	0.1	0.1	0.3	-0.1	-0.2	0.6	0.5	0.5	0.2	-0.1	-0.2	0.1	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.2	-0.3	-0.4	0.0	0.1	0.0	-0.3	-0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.4	1.9	0.6	0.3	0.9	0.1	1.4	0.5	0.5	-0.5	0.8	-0.2
Number of live births	0.0	0.0	0.1	0.1	0.3	-0.1	-0.1	0.2	-0.0	-0.1	-0.1	-0.0	0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.4	0.4	-0.6	-0.4	-0.0	-0.0	0.0	-0.3	-0.2	0.2	-0.0
Whole body fat-free mass	0.0	0.2	1.2	0.1	-0.7	-0.1	0.2	0.1	-0.0	-0.4	-0.6	0.2	-1.1
Eye problems/disorders: Cataract	0.0	0.0	0.1	-0.1	0.0	-0.1	-0.4	0.1	-0.0	0.3	0.3	-0.2	0.2
Whole body water mass	0.0	0.2	1.3	0.2	-0.7	-0.1	0.1	0.1	0.0	-0.3	-0.6	0.3	-1.1
Basal metabolic rate	0.0	0.2	0.6	0.3	-0.2	0.2	0.4	0.4	0.2	-0.3	-0.6	0.5	-0.8

Hub : Genes

DCHS1

Models

Trait associations