[Hub]/) : Traits : Blood Platelet Count :

chr14:64,156,218-66,906,467

Best TWAS P=4.57e-31 · Best GWAS P=8.49e-37 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FUT8 0.06 0.02 blup 516 0.03 1.2e-04 -4.45 8.1 8.4e-16 0.27 0.48 0.02 FALSE
2 CommonMind Brain Pre-frontal Cortex MAX 0.15 0.16 lasso 2 0.16 1.2e-18 11.31 -11.6 4.6e-31 -0.55 1.00 0.00 TRUE
3 CommonMind Brain Pre-frontal Cortex SPTB 0.06 0.05 bslmm 528 0.05 9.5e-07 2.86 -5.7 1.3e-08 -0.30 0.83 0.08 FALSE
4 GTEx Adipose Subcutaneous RAB15 0.48 0.07 enet 82 0.18 5.7e-15 0.59 5.6 2.5e-08 0.35 1.00 0.00 TRUE
5 GTEx Artery Aorta FUT8 0.13 0.01 enet 24 0.00 2.5e-01 -4.45 6.9 6.9e-12 0.22 0.26 0.04 FALSE
6 GTEx Artery Aorta SPTB 0.13 0.00 enet 11 0.01 9.0e-02 4.99 5.8 7.6e-09 0.23 0.08 0.05 FALSE
7 GTEx Brain Cerebellum ZBTB25 0.23 0.12 lasso 4 0.14 5.7e-05 -7.17 6.9 4.5e-12 0.07 0.24 0.05 FALSE
8 GTEx Breast Mammary Tissue (Female) RP11-840I19.5 0.06 -0.01 lasso 1 0.08 2.8e-03 -7.39 7.4 1.5e-13 0.15 0.04 0.06 TRUE
9 GTEx Cells Transformed fibroblasts RAB15 0.64 0.08 enet 41 0.33 1.3e-25 6.35 7.6 2.8e-14 0.46 1.00 0.00 FALSE
10 GTEx Colon Transverse MTHFD1 0.20 0.01 enet 49 0.02 6.2e-02 1.63 -7.0 3.0e-12 -0.20 0.14 0.37 TRUE
11 GTEx Esophagus Muscularis RAB15 0.35 0.06 enet 23 0.17 1.2e-10 6.35 6.1 1.0e-09 0.56 0.81 0.19 TRUE
12 GTEx Liver CHURC1 0.27 0.19 enet 31 0.17 2.1e-05 1.80 -5.8 7.9e-09 -0.36 0.57 0.04 FALSE
13 GTEx Muscle Skeletal FNTB 0.05 0.02 lasso 6 0.01 5.8e-02 9.78 -9.6 9.2e-22 -0.53 0.26 0.43 FALSE
14 GTEx Nerve Tibial RAB15 0.35 0.15 enet 68 0.18 4.7e-13 8.34 10.1 5.1e-24 0.43 1.00 0.00 FALSE
15 GTEx Pituitary RAB15 0.32 0.03 enet 16 0.10 1.9e-03 10.53 9.6 8.7e-22 0.63 0.16 0.44 TRUE
16 GTEx Spleen FUT8 0.17 0.03 lasso 3 0.02 9.9e-02 4.40 5.3 1.4e-07 0.02 0.16 0.05 FALSE
17 GTEx Testis RAB15 0.23 0.16 lasso 5 0.13 2.8e-06 6.35 6.8 1.5e-11 0.59 0.16 0.78 FALSE
18 GTEx Testis PPP1R36 0.29 0.25 enet 17 0.28 1.1e-12 -3.98 6.9 5.6e-12 0.36 1.00 0.00 TRUE
19 GTEx Thyroid RAB15 0.26 0.04 enet 52 0.08 1.5e-06 6.35 7.7 1.8e-14 0.41 0.90 0.08 TRUE
20 METSIM Adipose RAB15 0.10 0.04 enet 22 0.08 3.8e-12 8.49 6.8 7.1e-12 0.56 1.00 0.00 FALSE
21 YFS Blood FNTB 0.43 0.40 enet 18 0.42 1.1e-151 -7.12 -8.6 1.3e-17 0.16 1.00 0.00 TRUE
22 YFS Blood MAX 0.04 0.02 lasso 4 0.02 2.8e-06 7.64 -8.3 8.3e-17 -0.66 0.69 0.26 FALSE
23 The Cancer Genome Atlas Bladder Urothelial Carcinoma FNTB 0.10 0.03 blup 107 0.07 7.9e-07 1.86 -7.4 1.4e-13 -0.36 0.85 0.02 FALSE
24 The Cancer Genome Atlas Breast Invasive Carcinoma RAB15 0.02 0.01 blup 49 0.02 6.7e-05 2.64 6.6 3.8e-11 0.57 0.38 0.34 FALSE
25 The Cancer Genome Atlas Esophageal Carcinoma FNTB 0.09 0.05 lasso 3 0.04 2.6e-02 9.04 -7.8 6.3e-15 -0.61 0.06 0.22 FALSE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FNTB 0.06 0.02 blup 106 0.04 3.7e-05 2.22 -9.4 6.6e-21 -0.51 0.16 0.38 FALSE
27 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RAB15 0.03 0.00 blup 49 0.01 1.8e-02 8.20 6.2 5.9e-10 0.59 0.05 0.64 FALSE
28 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RAB15 0.14 0.07 enet 15 0.09 5.5e-10 8.34 8.7 2.9e-18 0.56 0.65 0.35 FALSE
29 The Cancer Genome Atlas Brain Lower Grade Glioma FUT8 0.04 0.02 lasso 4 0.02 3.6e-03 -5.81 5.7 1.6e-08 0.03 0.13 0.55 TRUE
30 The Cancer Genome Atlas Brain Lower Grade Glioma RAB15 0.04 0.05 blup 49 0.06 2.5e-07 2.64 7.0 2.2e-12 0.62 0.49 0.48 FALSE
31 The Cancer Genome Atlas Lung Adenocarcinoma RAB15 0.04 0.01 enet 5 0.03 1.9e-04 11.94 10.9 8.9e-28 0.82 0.00 0.97 TRUE
32 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RAB15 0.11 0.01 enet 12 0.06 1.1e-04 2.85 5.7 1.0e-08 0.51 0.02 0.85 FALSE
33 The Cancer Genome Atlas Prostate Adenocarcinoma RAB15 0.04 0.00 blup 49 0.01 6.9e-02 8.34 7.4 1.8e-13 0.51 0.11 0.11 TRUE
34 The Cancer Genome Atlas Soft Tissue Sarcoma FNTB 0.05 0.04 blup 107 0.03 6.5e-03 1.75 -5.3 9.1e-08 -0.51 0.22 0.17 FALSE