[Hub]/) : Traits : Hair Pigment :

chr1:6,149,122-11,326,788

Best TWAS P=7.79e-19 · Best GWAS P=4.94e-50 conditioned to 3.89e-39

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CAMTA1 0.10 0.07 lasso 3 0.07 1.9e-08 8.9 -8.9 7.8e-19 0.00 0.99 0.00 TRUE
2 CommonMind Brain Pre-frontal Cortex PARK7 0.05 0.00 bslmm 423 0.01 1.2e-02 -2.1 6.2 4.2e-10 -0.04 0.16 0.13 TRUE
3 GTEx Adipose Visceral Omentum RERE 0.22 0.17 lasso 5 0.17 5.2e-09 -4.9 5.6 2.5e-08 -0.03 0.96 0.02 FALSE
4 GTEx Brain Caudate basal ganglia KIF1B 0.25 0.00 lasso 5 0.02 1.1e-01 5.6 5.9 3.7e-09 -0.02 0.06 0.05 FALSE
5 GTEx Lung SLC45A1 0.09 0.00 enet 13 0.04 9.7e-04 -4.7 -5.5 2.8e-08 0.03 0.45 0.02 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic RERE 0.12 0.05 lasso 4 0.05 1.3e-03 -5.6 6.2 5.0e-10 0.00 0.58 0.02 FALSE
7 GTEx Skin Sun Exposed Lower leg RP3-467L1.6 0.12 0.01 lasso 3 0.02 1.5e-02 4.8 5.3 1.4e-07 0.00 0.14 0.04 FALSE
8 METSIM Adipose APITD1 0.04 0.05 lasso 3 0.03 5.1e-06 6.4 6.5 8.8e-11 0.01 0.98 0.01 FALSE
9 The Cancer Genome Atlas Bladder Urothelial Carcinoma CORT 0.04 0.05 lasso 6 0.04 1.7e-04 6.0 -6.0 1.5e-09 0.00 0.01 0.96 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma RERE 0.02 0.03 lasso 2 0.03 4.7e-07 -4.8 5.5 4.2e-08 -0.06 0.93 0.01 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma APITD1 0.05 0.02 blup 51 0.05 3.1e-06 6.1 6.4 1.6e-10 0.04 0.11 0.87 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma APITD1 0.04 0.03 lasso 3 0.02 1.4e-03 6.4 6.3 2.5e-10 0.01 0.00 0.98 FALSE
13 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MASP2 0.05 0.03 blup 30 0.04 6.0e-03 5.9 -8.4 3.9e-17 -0.49 0.03 0.28 TRUE
14 The Cancer Genome Atlas Lung Adenocarcinoma APITD1 0.02 0.02 blup 51 0.02 2.1e-03 3.2 5.4 7.0e-08 0.05 0.32 0.20 FALSE
15 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CORT 0.12 0.07 lasso 6 0.06 9.3e-05 6.0 -6.1 1.1e-09 -0.01 0.04 0.95 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma RERE 0.04 0.01 blup 154 0.01 3.1e-02 -4.4 7.2 8.9e-13 -0.06 0.06 0.03 TRUE
17 The Cancer Genome Atlas Stomach Adenocarcinoma CORT 0.06 0.03 enet 5 0.04 7.1e-04 6.2 -7.1 1.1e-12 0.00 0.04 0.84 TRUE