[Hub]/) : Traits : Hair Pigment :

chr2:233,047,291-234,434,621

Best TWAS P=5.17e-10 · Best GWAS P=1.68e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C2orf82 0.14 0.22 lasso 6 0.23 3.8e-27 -5.9 5.9 3.6e-09 -1.00 0.01 0.99 FALSE
2 GTEx Brain Caudate basal ganglia C2orf82 0.27 0.26 lasso 1 0.24 1.2e-07 -6.0 6.0 1.7e-09 -1.00 0.01 0.99 FALSE
3 GTEx Brain Cerebellum C2orf82 0.15 0.18 lasso 2 0.13 1.1e-04 -6.0 6.0 2.2e-09 -1.00 0.01 0.97 FALSE
4 GTEx Brain Cortex C2orf82 0.17 0.18 lasso 1 0.08 2.8e-03 -6.0 6.0 1.7e-09 -1.00 0.02 0.95 FALSE
5 GTEx Brain Frontal Cortex BA9 C2orf82 0.24 0.16 lasso 10 0.12 3.9e-04 -5.9 6.2 5.2e-10 -0.97 0.02 0.97 TRUE
6 GTEx Brain Nucleus accumbens basal ganglia C2orf82 0.19 0.18 lasso 5 0.14 1.1e-04 -6.0 5.8 9.0e-09 -0.96 0.01 0.97 FALSE
7 GTEx Brain Putamen basal ganglia C2orf82 0.28 0.22 lasso 3 0.18 5.3e-05 -6.0 6.2 6.1e-10 -0.98 0.02 0.91 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic C2orf82 0.19 0.19 lasso 5 0.20 5.5e-11 -6.0 5.9 3.9e-09 -0.99 0.00 1.00 FALSE
9 GTEx Skin Sun Exposed Lower leg C2orf82 0.16 0.14 lasso 4 0.15 1.3e-12 -6.0 6.0 1.5e-09 -0.98 0.00 1.00 FALSE
10 ROSMAP Brain Pre-frontal Cortex C2orf82 0.31 0.50 enet 24 0.50 1.3e-73 -5.9 6.1 8.2e-10 -0.99 0.01 0.99 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme C2orf82 0.20 0.24 lasso 8 0.20 9.1e-07 -5.9 5.9 3.3e-09 -0.99 0.01 0.99 FALSE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EFHD1 0.11 0.01 blup 70 0.03 1.0e-02 2.0 5.2 2.7e-07 -0.39 0.01 0.53 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma C2orf82 0.14 0.20 enet 6 0.19 3.1e-21 -5.9 5.9 3.1e-09 -0.98 0.01 0.99 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma NGEF 0.03 0.01 blup 130 0.01 2.0e-02 -5.2 5.4 5.3e-08 -0.91 0.01 0.92 FALSE
15 The Cancer Genome Atlas Pancreatic Adenocarcinoma KCNJ13 0.07 0.07 blup 36 0.06 2.4e-03 -5.2 5.5 3.8e-08 -0.78 0.01 0.87 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma GIGYF2 0.04 0.00 blup 103 0.02 2.1e-03 -5.9 -6.2 5.8e-10 0.83 0.02 0.90 FALSE