[Hub]/) : Traits : Tanning : ← →

chr11:77,027,574-78,828,001

Best TWAS P=1.57e-10 · Best GWAS P=3.12e-11 conditioned to 0.0293

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum ALG8 0.11 0.01 enet 8 0.02 3.7e-02 5.6 5.2 2.1e-07 0.73 0.14 0.39 FALSE
2 GTEx Artery Tibial GAB2 0.06 0.00 lasso 2 0.01 2.4e-02 6.2 -6.2 6.0e-10 -0.90 0.05 0.80 FALSE
3 GTEx Brain Cerebellar Hemisphere USP35 0.19 0.07 enet 13 0.09 2.5e-03 5.6 6.4 1.6e-10 0.87 0.07 0.72 TRUE
4 GTEx Esophagus Muscularis GAB2 0.05 0.04 lasso 7 0.04 1.8e-03 5.5 -6.0 1.6e-09 -0.89 0.15 0.76 FALSE
5 GTEx Liver GAB2 0.17 -0.01 enet 20 -0.01 5.6e-01 6.0 5.5 3.1e-08 0.74 0.05 0.47 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic RP11-7I15.3 0.07 0.01 lasso 3 0.02 3.5e-02 6.3 6.1 1.4e-09 0.79 0.06 0.78 FALSE
7 GTEx Testis USP35 0.07 0.06 lasso 2 0.07 6.4e-04 6.3 6.4 2.0e-10 0.89 0.06 0.89 FALSE
8 METSIM Adipose USP35 0.05 0.05 lasso 11 0.04 3.0e-06 6.2 6.2 7.5e-10 0.89 0.05 0.95 FALSE
9 ROSMAP Brain Pre-frontal Cortex GAB2 0.05 0.00 blup 435 0.02 8.0e-04 4.4 -5.4 5.9e-08 -0.81 0.16 0.77 FALSE
10 The Cancer Genome Atlas Glioblastoma Multiforme GAB2 0.10 0.07 blup 100 0.09 8.8e-04 5.9 -6.2 8.0e-10 -0.93 0.05 0.64 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma GAB2 0.06 0.06 blup 100 0.07 7.8e-08 6.2 -6.4 1.8e-10 -0.94 0.06 0.94 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma GAB2 0.04 0.04 blup 100 0.04 1.4e-03 5.6 -6.3 3.5e-10 -0.91 0.04 0.90 FALSE