[Hub]/) : Traits : Alzheimer’s Disease (in father) : ←

chr19:44,190,626-46,680,895

Best TWAS P=2.68e-30 · Best GWAS P=8.26e-193 conditioned to 2.42e-22

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	ZNF285	0.17	0.05	enet	20	0.07	1.3e-04	-0.39	-7.7	1.1e-14	-0.17	0.39	0.15	TRUE
2	GTEx	Nerve Tibial	ERCC1	0.21	0.09	enet	47	0.10	2.1e-07	1.33	-6.8	9.4e-12	-0.15	0.61	0.08	TRUE
3	GTEx	Skin Not Sun Exposed Suprapubic	ZNF229	0.28	0.09	enet	58	0.08	2.2e-05	-1.50	-9.6	1.3e-21	-0.27	0.10	0.47	FALSE
4	GTEx	Thyroid	CEACAM19	0.34	0.28	enet	26	0.30	9.9e-24	4.82	6.8	1.4e-11	0.09	1.00	0.00	TRUE
5	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	APOC1P1	0.05	0.03	blup	37	0.03	5.2e-04	-7.28	9.7	2.1e-22	0.22	0.14	0.20	TRUE
6	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TOMM40	0.04	0.03	lasso	2	0.02	1.4e-03	-11.48	11.4	2.7e-30	0.22	0.12	0.09	TRUE
7	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	APOC1	0.05	0.00	blup	47	0.01	4.3e-02	-1.36	-10.4	4.0e-25	-0.32	0.01	0.06	TRUE
8	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	APOE	0.06	0.00	blup	49	0.01	4.5e-02	-1.36	-8.6	9.6e-18	-0.29	0.02	0.06	TRUE
9	The Cancer Genome Atlas	Prostate Adenocarcinoma	TOMM40	0.08	0.07	enet	13	0.07	2.2e-07	-11.48	6.8	1.4e-11	0.14	1.00	0.00	TRUE
10	The Cancer Genome Atlas	Testicular Germ Cell Tumors	APOC1P1	0.14	0.01	blup	36	0.06	3.8e-03	-0.47	6.6	3.9e-11	0.20	0.01	0.07	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	PVRL2	0.09	0.05	blup	55	0.03	4.6e-04	-0.85	-6.4	1.6e-10	-0.05	0.48	0.05	TRUE
12	The Cancer Genome Atlas	Thyroid Carcinoma	TOMM40	0.05	0.07	lasso	3	0.06	1.1e-06	-9.67	9.2	2.8e-20	0.19	0.89	0.01	TRUE
13	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	APOC2	0.20	0.14	enet	10	0.14	7.9e-05	1.75	-5.5	4.1e-08	-0.08	0.15	0.05	TRUE